locus-tag	class	description
B1U23_RS00010	COG1472	Belongs to the glycosyl hydrolase 3 family
B1U23_RS00020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B1U23_RS00085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B1U23_RS00155	COG0681	Belongs to the peptidase S26 family
B1U23_RS00220	COG1196	nuclear chromosome segregation
B1U23_RS00245	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
B1U23_RS00335	COG0561	phosphatase activity
B1U23_RS00340	COG2309	aminopeptidase activity
B1U23_RS00345	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
B1U23_RS00375	COG0552	protein localization to endoplasmic reticulum
B1U23_RS00385	COG4591	ABC-type transport system involved in lipoprotein release permease component
B1U23_RS00390	COG1136	(ABC) transporter
B1U23_RS00420	COG0606	chelatase, subunit chli
B1U23_RS00510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B1U23_RS00545	COG0305	Participates in initiation and elongation during chromosome replication
B1U23_RS00570	COG1263	PTS System
B1U23_RS00570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B1U23_RS00570	COG2190	(PTS) system
B1U23_RS00585	COG4589	Belongs to the CDS family
B1U23_RS00625	COG0539	negative regulation of cytoplasmic translation
B1U23_RS00670	COG0768	penicillin binding
B1U23_RS00675	COG1022	Amp-dependent synthetase and ligase
B1U23_RS00715	COG4176	ABC-type proline glycine betaine transport system permease component
B1U23_RS00720	COG3448	diguanylate cyclase activity
B1U23_RS00720	COG4175	Glycine betaine
B1U23_RS00735	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B1U23_RS00860	COG0714	Associated with various cellular activities
B1U23_RS00905	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B1U23_RS00945	COG0084	hydrolase, TatD family'
B1U23_RS00990	COG4536	flavin adenine dinucleotide binding
B1U23_RS01020	COG0742	ribosomal rna small subunit methyltransferase
B1U23_RS01025	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B1U23_RS01075	COG0573	inorganic phosphate transmembrane transporter activity
B1U23_RS01080	COG0581	inorganic phosphate transmembrane transporter activity
B1U23_RS01100	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B1U23_RS01120	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B1U23_RS01170	COG0012	GTP binding
B1U23_RS01190	COG1428	Deoxynucleoside kinase
B1U23_RS01195	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B1U23_RS01210	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B1U23_RS01225	COG0739	heme binding
B1U23_RS01270	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B1U23_RS01275	COG0739	heme binding
B1U23_RS01315	COG0681	Belongs to the peptidase S26 family
B1U23_RS01320	COG0443	Heat shock 70 kDa protein
B1U23_RS01400	COG1360	Flagellar Motor Protein
B1U23_RS01410	COG1582	Flagellar protein (FlbD)
B1U23_RS01420	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
B1U23_RS01505	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B1U23_RS01555	COG0835	chemotaxis
B1U23_RS01650	COG0601	transmembrane transport
B1U23_RS01655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1U23_RS01660	COG0444	Belongs to the ABC transporter superfamily
B1U23_RS01665	COG4608	Belongs to the ABC transporter superfamily
B1U23_RS01710	COG0210	DNA helicase
B1U23_RS01780	COG0793	Belongs to the peptidase S41A family
B1U23_RS01790	COG0455	bacterial-type flagellum organization
B1U23_RS01825	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B1U23_RS01830	COG0542	response to heat
B1U23_RS01860	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B1U23_RS01885	COG2239	Acts as a magnesium transporter
B1U23_RS02035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B1U23_RS02035	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B1U23_RS02035	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B1U23_RS02115	COG0561	phosphatase activity
B1U23_RS02150	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
B1U23_RS02165	COG1739	Uncharacterized protein family UPF0029
B1U23_RS02170	COG1192	Involved in chromosome partitioning
B1U23_RS02265	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B1U23_RS02280	COG0668	transmembrane transport
B1U23_RS02345	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B1U23_RS02370	COG1137	ATPase activity
B1U23_RS02530	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B1U23_RS02560	COG1692	metallophosphoesterase
B1U23_RS02565	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
B1U23_RS02630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B1U23_RS02630	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
B1U23_RS02655	COG0667	Aldo Keto reductase
B1U23_RS02675	COG0321	lipoyl(octanoyl) transferase activity
B1U23_RS02675	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
B1U23_RS02680	COG0708	Exodeoxyribonuclease III
B1U23_RS02690	COG0612	Peptidase, M16
B1U23_RS02775	COG2201	protein-glutamate methylesterase activity
B1U23_RS02825	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
B1U23_RS02845	COG0835	chemotaxis
B1U23_RS02855	COG2198	Histidine kinase
B1U23_RS02855	COG0643	Histidine kinase
B1U23_RS02870	COG4566	intracellular signal transduction
B1U23_RS02880	COG0528	UMP kinase activity
B1U23_RS02885	COG1216	Glycosyl transferase, family 2
B1U23_RS02890	COG1121	(ABC) transporter
B1U23_RS02915	COG0840	transmembrane signaling receptor activity
B1U23_RS02915	COG3290	protein histidine kinase activity
B1U23_RS02940	COG0534	Mate efflux family protein
B1U23_RS02960	COG2348	transferase activity, transferring amino-acyl groups
B1U23_RS02970	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B1U23_RS02985	COG2333	competence protein COMEC
B1U23_RS02985	COG0658	competence protein
B1U23_RS02995	COG1022	Amp-dependent synthetase and ligase
B1U23_RS03010	COG0840	transmembrane signaling receptor activity
B1U23_RS03015	COG0840	transmembrane signaling receptor activity
B1U23_RS03015	COG5278	phosphoserine phosphatase activity
B1U23_RS03040	COG0484	heat shock protein binding
B1U23_RS03050	COG1620	l-lactate permease
B1U23_RS03055	COG1686	Belongs to the peptidase S11 family
B1U23_RS03065	COG0210	DNA helicase
B1U23_RS03070	COG2195	Cleaves the N-terminal amino acid of tripeptides
B1U23_RS03140	COG0295	cytidine deaminase activity
B1U23_RS03180	COG0791	NLP P60 protein
B1U23_RS03180	COG1388	LysM domain
B1U23_RS03180	COG3103	Sh3 type 3 domain protein
B1U23_RS03205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B1U23_RS03205	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B1U23_RS03205	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B1U23_RS03225	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B1U23_RS03240	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
B1U23_RS03255	COG1757	Na H antiporter
B1U23_RS03265	COG1177	transmembrane transport
B1U23_RS03270	COG1176	ABC-type spermidine putrescine transport system, permease component I
B1U23_RS03280	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
B1U23_RS03290	COG2190	(PTS) system
B1U23_RS03290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B1U23_RS03290	COG1263	PTS System
B1U23_RS03340	COG0484	heat shock protein binding
B1U23_RS03345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B1U23_RS03395	COG0860	N-Acetylmuramoyl-L-alanine amidase
B1U23_RS03415	COG0835	chemotaxis
B1U23_RS03425	COG2201	protein-glutamate methylesterase activity
B1U23_RS03450	COG3845	ABC transporter
B1U23_RS03455	COG4603	Belongs to the binding-protein-dependent transport system permease family
B1U23_RS03460	COG1079	Belongs to the binding-protein-dependent transport system permease family
B1U23_RS03465	COG0840	transmembrane signaling receptor activity
B1U23_RS03470	COG0840	transmembrane signaling receptor activity
B1U23_RS03480	COG3425	synthase
B1U23_RS03520	COG0783	Belongs to the Dps family
B1U23_RS03535	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B1U23_RS03590	COG0617	tRNA 3'-terminal CCA addition
B1U23_RS03615	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B1U23_RS03645	COG1077	Cell shape determining protein MreB Mrl
B1U23_RS03660	COG0768	penicillin binding
B1U23_RS03665	COG0772	Belongs to the SEDS family
B1U23_RS03675	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B1U23_RS03690	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B1U23_RS03700	COG0003	Pfam Anion-transporting ATPase
B1U23_RS03710	COG0446	pyridine nucleotide-disulphide oxidoreductase
B1U23_RS03725	COG1475	DNA binding
B1U23_RS03740	COG0009	L-threonylcarbamoyladenylate synthase
B1U23_RS03745	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B1U23_RS03765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B1U23_RS03765	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
B1U23_RS03775	COG0488	(ABC) transporter
B1U23_RS03800	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B1U23_RS03805	COG4239	(ABC) transporter, permease
B1U23_RS03810	COG4168	peptide transport system, permease
B1U23_RS03840	COG1131	(ABC) transporter
B1U23_RS03850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B1U23_RS03880	COG0739	heme binding
B1U23_RS03885	COG2204	response regulator
B1U23_RS03890	COG5002	protein histidine kinase activity
B1U23_RS03895	COG0470	DNA polymerase III
B1U23_RS03925	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B1U23_RS04045	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B1U23_RS04055	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B1U23_RS04070	COG1040	competence protein
B1U23_RS04145	COG4145	pantothenate transmembrane transporter activity
B1U23_RS04150	COG0564	pseudouridine synthase activity
B1U23_RS04165	COG1561	YicC-like family, N-terminal region
B1U23_RS04220	COG0419	ATPase involved in DNA repair
B1U23_RS04225	COG1940	carbohydrate kinase activity
B1U23_RS04245	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B1U23_RS04290	COG1288	antiporter activity
B1U23_RS04340	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B1U23_RS04345	COG1447	Phosphotransferase system cellobiose-specific component IIA
B1U23_RS04350	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B1U23_RS04420	COG2252	PERMEase
B1U23_RS04425	COG2252	PERMEase
B1U23_RS04455	COG2190	(PTS) system
B1U23_RS04455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B1U23_RS04455	COG1263	PTS System
B1U23_RS04615	COG1192	Involved in chromosome partitioning
B1U23_RS04840	COG1192	Involved in chromosome partitioning
B1U23_RS05050	COG1192	Involved in chromosome partitioning
B1U23_RS05260	COG1192	Involved in chromosome partitioning
B1U23_RS05700	COG1192	Involved in chromosome partitioning
B1U23_RS05905	COG1192	Involved in chromosome partitioning
B1U23_RS05945	COG1136	(ABC) transporter
B1U23_RS06115	COG1192	Involved in chromosome partitioning
B1U23_RS06160	COG4166	transmembrane transport