locus-tag	class	description
P613_RS00005	COG1472	Belongs to the glycosyl hydrolase 3 family
P613_RS00015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
P613_RS00045	COG0736	holo-[acyl-carrier-protein] synthase activity
P613_RS00055	COG0101	tRNA pseudouridine synthase activity
P613_RS00080	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
P613_RS00100	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
P613_RS00110	COG0632	four-way junction helicase activity
P613_RS00125	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
P613_RS00150	COG0681	Belongs to the peptidase S26 family
P613_RS00215	COG1196	nuclear chromosome segregation
P613_RS00235	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
P613_RS00265	COG0126	phosphoglycerate kinase activity
P613_RS00305	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
P613_RS00325	COG0561	phosphatase activity
P613_RS00330	COG2309	aminopeptidase activity
P613_RS00335	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
P613_RS00365	COG0552	protein localization to endoplasmic reticulum
P613_RS00375	COG4591	ABC-type transport system involved in lipoprotein release permease component
P613_RS00380	COG1136	(ABC) transporter
P613_RS00410	COG0606	chelatase, subunit chli
P613_RS00415	COG0039	L-malate dehydrogenase activity
P613_RS00460	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
P613_RS00475	COG1162	GTPase activity
P613_RS00500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
P613_RS00515	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
P613_RS00535	COG0305	Participates in initiation and elongation during chromosome replication
P613_RS00545	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
P613_RS00560	COG1263	PTS System
P613_RS00560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
P613_RS00560	COG2190	(PTS) system
P613_RS00575	COG4589	Belongs to the CDS family
P613_RS00590	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
P613_RS00595	COG0052	Belongs to the universal ribosomal protein uS2 family
P613_RS00615	COG0539	negative regulation of cytoplasmic translation
P613_RS00620	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
P613_RS00635	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
P613_RS00660	COG0768	penicillin binding
P613_RS00665	COG1022	Amp-dependent synthetase and ligase
P613_RS00690	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
P613_RS00700	COG4176	ABC-type proline glycine betaine transport system permease component
P613_RS00705	COG3448	diguanylate cyclase activity
P613_RS00705	COG4175	Glycine betaine
P613_RS00720	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
P613_RS00790	COG1640	4-alpha-glucanotransferase
P613_RS00840	COG0714	Associated with various cellular activities
P613_RS00845	COG0357	Ribosomal RNA small subunit methyltransferase G
P613_RS00850	COG0445	tRNA wobble uridine modification
P613_RS00870	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
P613_RS00875	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
P613_RS00880	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
P613_RS00900	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
P613_RS00905	COG0291	Belongs to the bacterial ribosomal protein bL35 family
P613_RS00910	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
P613_RS00925	COG0084	hydrolase, TatD family'
P613_RS00935	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
P613_RS00960	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
P613_RS00970	COG4536	flavin adenine dinucleotide binding
P613_RS01000	COG0742	ribosomal rna small subunit methyltransferase
P613_RS01025	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
P613_RS01045	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
P613_RS01055	COG0573	inorganic phosphate transmembrane transporter activity
P613_RS01060	COG0581	inorganic phosphate transmembrane transporter activity
P613_RS01065	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
P613_RS01075	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
P613_RS01080	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
P613_RS01100	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
P613_RS01105	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
P613_RS01150	COG0012	GTP binding
P613_RS01170	COG1428	Deoxynucleoside kinase
P613_RS01180	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
P613_RS01185	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
P613_RS01195	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
P613_RS01210	COG0739	heme binding
P613_RS01215	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
P613_RS01240	COG0495	leucyl-tRNA aminoacylation
P613_RS01255	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
P613_RS01260	COG0739	heme binding
P613_RS01300	COG0681	Belongs to the peptidase S26 family
P613_RS01305	COG0443	Heat shock 70 kDa protein
P613_RS01385	COG1360	Flagellar Motor Protein
P613_RS01395	COG1582	Flagellar protein (FlbD)
P613_RS01405	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
P613_RS01515	COG0275	rRNA processing
P613_RS01540	COG0835	chemotaxis
P613_RS01625	COG0601	transmembrane transport
P613_RS01630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
P613_RS01635	COG0444	Belongs to the ABC transporter superfamily
P613_RS01640	COG4608	Belongs to the ABC transporter superfamily
P613_RS01650	COG0148	phosphopyruvate hydratase activity
P613_RS01655	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
P613_RS01660	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
P613_RS01670	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
P613_RS01675	COG0154	amidase activity
P613_RS01755	COG0793	Belongs to the peptidase S41A family
P613_RS01760	COG0455	bacterial-type flagellum organization
P613_RS01765	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
P613_RS01775	COG1803	Methylglyoxal synthase
P613_RS01785	COG1362	aminopeptidase activity
P613_RS01795	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
P613_RS01800	COG0542	response to heat
P613_RS01805	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
P613_RS01830	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
P613_RS01835	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
P613_RS01840	COG1854	S-ribosylhomocysteine lyase activity
P613_RS01855	COG2239	Acts as a magnesium transporter
P613_RS01865	COG1744	ABC transporter substrate-binding protein PnrA-like
P613_RS01870	COG1744	ABC transporter substrate-binding protein PnrA-like
P613_RS01885	COG0049	tRNA binding
P613_RS01900	COG0085	RNA polymerase activity
P613_RS01910	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
P613_RS01920	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
P613_RS01975	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
P613_RS02005	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
P613_RS02005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
P613_RS02005	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
P613_RS02045	COG0563	adenylate kinase activity
P613_RS02085	COG0561	phosphatase activity
P613_RS02090	COG2094	Belongs to the DNA glycosylase MPG family
P613_RS02115	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
P613_RS02130	COG1739	Uncharacterized protein family UPF0029
P613_RS02135	COG1192	Involved in chromosome partitioning
P613_RS02160	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
P613_RS02175	COG0230	Belongs to the bacterial ribosomal protein bL34 family
P613_RS02180	COG0594	ribonuclease P activity
P613_RS02185	COG0706	membrane insertase activity
P613_RS02225	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
P613_RS02240	COG0668	transmembrane transport
P613_RS02260	COG0322	excinuclease ABC activity
P613_RS02305	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
P613_RS02330	COG1137	ATPase activity
P613_RS02345	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
P613_RS02385	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
P613_RS02390	COG0088	Forms part of the polypeptide exit tunnel
P613_RS02410	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
P613_RS02415	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
P613_RS02420	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
P613_RS02430	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
P613_RS02440	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
P613_RS02450	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
P613_RS02455	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
P613_RS02470	COG1841	ribosomal large subunit assembly
P613_RS02475	COG0200	Binds to the 23S rRNA
P613_RS02485	COG0257	Belongs to the bacterial ribosomal protein bL36 family
P613_RS02505	COG0203	ribosomal protein L17
P613_RS02515	COG1692	metallophosphoesterase
P613_RS02520	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
P613_RS02530	COG1160	GTP binding
P613_RS02555	COG0072	phenylalanine-tRNA ligase activity
P613_RS02575	COG0443	Heat shock 70 kDa protein
P613_RS02580	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
P613_RS02585	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
P613_RS02585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
P613_RS02605	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
P613_RS02610	COG0667	Aldo Keto reductase
P613_RS02630	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
P613_RS02630	COG0321	lipoyl(octanoyl) transferase activity
P613_RS02635	COG0708	Exodeoxyribonuclease III
P613_RS02645	COG0612	Peptidase, M16
P613_RS02675	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
P613_RS02730	COG2201	protein-glutamate methylesterase activity
P613_RS02780	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
P613_RS02810	COG2198	Histidine kinase
P613_RS02810	COG0643	Histidine kinase
P613_RS02825	COG0745	RESPONSE REGULATOR receiver
P613_RS02835	COG0528	UMP kinase activity
P613_RS02840	COG1216	Glycosyl transferase, family 2
P613_RS02845	COG4555	ABC transporter
P613_RS02855	COG0504	CTP synthase activity
P613_RS02870	COG0840	transmembrane signaling receptor activity
P613_RS02905	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
P613_RS02910	COG2348	transferase activity, transferring amino-acyl groups
P613_RS02915	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
P613_RS02915	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
P613_RS02920	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
P613_RS02930	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
P613_RS02945	COG1022	Amp-dependent synthetase and ligase
P613_RS02950	COG0018	arginyl-trna synthetase
P613_RS02960	COG0840	transmembrane signaling receptor activity
P613_RS02965	COG0840	transmembrane signaling receptor activity
P613_RS02965	COG5278	phosphoserine phosphatase activity
P613_RS02970	COG0812	UDP-N-acetylmuramate dehydrogenase activity
P613_RS02975	COG0215	cysteine-tRNA ligase activity
P613_RS02985	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
P613_RS02990	COG0484	heat shock protein binding
P613_RS03000	COG1620	l-lactate permease
P613_RS03005	COG1686	Belongs to the peptidase S11 family
P613_RS03010	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
P613_RS03015	COG0210	DNA helicase
P613_RS03020	COG2195	Cleaves the N-terminal amino acid of tripeptides
P613_RS03045	COG0544	peptidyl-prolyl cis-trans isomerase activity
P613_RS03050	COG0740	serine-type endopeptidase activity
P613_RS03055	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
P613_RS03065	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
P613_RS03110	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
P613_RS03125	COG0860	N-Acetylmuramoyl-L-alanine amidase
P613_RS03150	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
P613_RS03150	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
P613_RS03150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
P613_RS03170	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
P613_RS03185	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
P613_RS03210	COG1177	transmembrane transport
P613_RS03215	COG1176	ABC-type spermidine putrescine transport system, permease component I
P613_RS03225	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
P613_RS03235	COG1263	PTS System
P613_RS03235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
P613_RS03235	COG2190	(PTS) system
P613_RS03255	COG0459	protein refolding
P613_RS03285	COG0484	heat shock protein binding
P613_RS03290	COG0635	Involved in the biosynthesis of porphyrin-containing compound
P613_RS03295	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
P613_RS03340	COG0860	N-Acetylmuramoyl-L-alanine amidase
P613_RS03360	COG0835	chemotaxis
P613_RS03370	COG2201	protein-glutamate methylesterase activity
P613_RS03395	COG3845	ABC transporter
P613_RS03400	COG4603	Belongs to the binding-protein-dependent transport system permease family
P613_RS03405	COG1079	Belongs to the binding-protein-dependent transport system permease family
P613_RS03415	COG0840	transmembrane signaling receptor activity
P613_RS03425	COG3425	synthase
P613_RS03465	COG0783	Belongs to the Dps family
P613_RS03480	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
P613_RS03485	COG0228	four-way junction DNA binding
P613_RS03495	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
P613_RS03500	COG0336	Belongs to the RNA methyltransferase TrmD family
P613_RS03515	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
P613_RS03525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
P613_RS03530	COG0571	ribonuclease III activity
P613_RS03535	COG0617	tRNA 3'-terminal CCA addition
P613_RS03560	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
P613_RS03585	COG1077	Cell shape determining protein MreB Mrl
P613_RS03600	COG0768	penicillin binding
P613_RS03605	COG0772	Belongs to the SEDS family
P613_RS03615	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
P613_RS03630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
P613_RS03640	COG0003	Pfam Anion-transporting ATPase
P613_RS03650	COG0446	pyridine nucleotide-disulphide oxidoreductase
P613_RS03660	COG0166	Belongs to the GPI family
P613_RS03665	COG1475	DNA binding
P613_RS03680	COG0009	L-threonylcarbamoyladenylate synthase
P613_RS03685	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
P613_RS03695	COG0525	valine-tRNA ligase activity
P613_RS03705	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
P613_RS03705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
P613_RS03710	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
P613_RS03715	COG0488	(ABC) transporter
P613_RS03740	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
P613_RS03745	COG4239	(ABC) transporter, permease
P613_RS03750	COG4168	peptide transport system, permease
P613_RS03780	COG1131	(ABC) transporter
P613_RS03785	COG1234	tRNA 3'-trailer cleavage
P613_RS03790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
P613_RS03820	COG0739	heme binding
P613_RS03825	COG2204	response regulator
P613_RS03830	COG5002	protein histidine kinase activity
P613_RS03835	COG0470	DNA polymerase III
P613_RS03845	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
P613_RS03865	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
P613_RS03890	COG4786	Flagellar basal body rod
P613_RS03900	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
P613_RS03925	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
P613_RS03940	COG2088	sporulation resulting in formation of a cellular spore
P613_RS03955	COG0193	aminoacyl-tRNA hydrolase activity
P613_RS03960	COG0037	tRNA processing
P613_RS03985	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
P613_RS03995	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
P613_RS04005	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
P613_RS04010	COG1040	competence protein
P613_RS04015	COG0779	Required for maturation of 30S ribosomal subunits
P613_RS04030	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
P613_RS04035	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
P613_RS04045	COG1185	polyribonucleotide nucleotidyltransferase activity
P613_RS04065	COG0343	queuine tRNA-ribosyltransferase activity
P613_RS04090	COG4145	pantothenate transmembrane transporter activity
P613_RS04095	COG0564	pseudouridine synthase activity
P613_RS04105	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
P613_RS04110	COG1561	YicC-like family, N-terminal region
P613_RS04115	COG1102	Psort location Cytoplasmic, score
P613_RS04165	COG0419	ATPase involved in DNA repair
P613_RS04170	COG1940	carbohydrate kinase activity
P613_RS04180	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
P613_RS04190	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
P613_RS04195	COG0556	nucleotide-excision repair
P613_RS04225	COG2235	arginine
P613_RS04235	COG1288	antiporter activity
P613_RS04250	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
P613_RS04460	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
P613_RS04535	COG0632	four-way junction helicase activity