locus-tag	class	description
AXW83_RS00010	COG0437	4 iron, 4 sulfur cluster binding
AXW83_RS00020	COG1763	Mo-molybdopterin cofactor biosynthetic process
AXW83_RS00025	COG0303	'Molybdopterin
AXW83_RS00035	COG0730	response to heat
AXW83_RS00050	COG1960	acyl-CoA dehydrogenase activity
AXW83_RS00055	COG0183	Belongs to the thiolase family
AXW83_RS00060	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXW83_RS00060	COG1024	Enoyl-CoA hydratase
AXW83_RS00065	COG0242	peptide deformylase activity
AXW83_RS00070	COG2161	toxin-antitoxin pair type II binding
AXW83_RS00075	COG4115	mRNA cleavage
AXW83_RS00085	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AXW83_RS00105	COG0745	RESPONSE REGULATOR receiver
AXW83_RS00110	COG2030	dehydratase
AXW83_RS00115	COG0196	riboflavin kinase activity
AXW83_RS00120	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AXW83_RS00125	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AXW83_RS00135	COG0612	Peptidase, M16
AXW83_RS00140	COG0612	Peptidase, M16
AXW83_RS00145	COG0166	Belongs to the GPI family
AXW83_RS00150	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AXW83_RS00165	COG0742	ribosomal rna small subunit methyltransferase
AXW83_RS00170	COG1187	pseudouridine synthase activity
AXW83_RS00175	COG0590	tRNA wobble adenosine to inosine editing
AXW83_RS00200	COG0596	Alpha beta hydrolase
AXW83_RS00210	COG0151	Belongs to the GarS family
AXW83_RS00215	COG1570	exodeoxyribonuclease VII activity
AXW83_RS00230	COG1663	tetraacyldisaccharide 4'-kinase activity
AXW83_RS00235	COG1519	Transferase
AXW83_RS00250	COG0483	inositol monophosphate 1-phosphatase activity
AXW83_RS00260	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AXW83_RS00275	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AXW83_RS00305	COG0583	DNA-binding transcription factor activity
AXW83_RS00325	COG0475	glutathione-regulated potassium exporter activity
AXW83_RS00325	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AXW83_RS00330	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AXW83_RS00335	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AXW83_RS00340	COG0328	RNA-DNA hybrid ribonuclease activity
AXW83_RS00355	COG0678	peroxiredoxin activity
AXW83_RS00355	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AXW83_RS00365	COG1678	Uncharacterized ACR, COG1678
AXW83_RS00380	COG0612	Peptidase, M16
AXW83_RS00390	COG3346	SURF1 family
AXW83_RS00405	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AXW83_RS00410	COG0109	protoheme IX farnesyltransferase activity
AXW83_RS00415	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AXW83_RS00420	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AXW83_RS00435	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AXW83_RS00440	COG0509	glycine decarboxylation via glycine cleavage system
AXW83_RS00445	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AXW83_RS00450	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AXW83_RS00470	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AXW83_RS00475	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AXW83_RS00485	COG0356	it plays a direct role in the translocation of protons across the membrane
AXW83_RS00495	COG1196	nuclear chromosome segregation
AXW83_RS00515	COG1194	a g-specific adenine glycosylase
AXW83_RS00520	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AXW83_RS00525	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AXW83_RS00540	COG2321	neutral zinc metallopeptidase
AXW83_RS00545	COG3077	Addiction module antitoxin, RelB DinJ family
AXW83_RS00550	COG3668	Plasmid stabilization system
AXW83_RS00555	COG1294	oxidase, subunit
AXW83_RS00560	COG1271	oxidase subunit
AXW83_RS00565	COG1573	uracil-dna glycosylase
AXW83_RS00585	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AXW83_RS00595	COG0142	geranyltranstransferase activity
AXW83_RS00610	COG0752	glycyl-tRNA synthetase alpha subunit
AXW83_RS00625	COG0138	bifunctional purine biosynthesis protein purh
AXW83_RS00640	COG3181	Tripartite tricarboxylate transporter family receptor
AXW83_RS00665	COG0625	glutathione transferase activity
AXW83_RS00675	COG0583	DNA-binding transcription factor activity
AXW83_RS00680	COG2205	protein histidine kinase activity
AXW83_RS00750	COG4974	Belongs to the 'phage' integrase family
AXW83_RS00775	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AXW83_RS00780	COG0235	Class ii aldolase
AXW83_RS00790	COG1301	dicarboxylic acid transport
AXW83_RS00795	COG2186	Transcriptional regulator
AXW83_RS00800	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AXW83_RS00805	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AXW83_RS00810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AXW83_RS00815	COG1611	Belongs to the LOG family
AXW83_RS00835	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AXW83_RS00845	COG0072	phenylalanine-tRNA ligase activity
AXW83_RS00845	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXW83_RS00855	COG0596	Alpha beta hydrolase
AXW83_RS00860	COG0473	3-isopropylmalate dehydrogenase activity
AXW83_RS00865	COG0861	Integral membrane protein TerC family
AXW83_RS00885	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AXW83_RS00890	COG0728	peptidoglycan biosynthetic process
AXW83_RS00895	COG0463	Glycosyl transferase, family 2
AXW83_RS00900	COG3394	polysaccharide catabolic process
AXW83_RS00910	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AXW83_RS00925	COG4957	zinc ion binding
AXW83_RS00940	COG2166	iron-sulfur cluster assembly
AXW83_RS00950	COG2205	protein histidine kinase activity
AXW83_RS00990	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AXW83_RS00995	COG2983	Belongs to the UPF0260 family
AXW83_RS01005	COG0574	Belongs to the PEP-utilizing enzyme family
AXW83_RS01005	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AXW83_RS01030	COG1278	Cold shock
AXW83_RS01035	COG0513	Belongs to the DEAD box helicase family
AXW83_RS01040	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AXW83_RS01065	COG3773	Cell wall hydrolase
AXW83_RS01065	COG3409	Peptidoglycan-binding domain 1 protein
AXW83_RS01075	COG0604	alcohol dehydrogenase
AXW83_RS01090	COG0583	DNA-binding transcription factor activity
AXW83_RS01095	COG0009	L-threonylcarbamoyladenylate synthase
AXW83_RS01100	COG1960	acyl-CoA dehydrogenase activity
AXW83_RS01105	COG2226	methyltransferase
AXW83_RS01110	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS01115	COG0247	lactate metabolic process
AXW83_RS01120	COG0277	FAD linked oxidase domain protein
AXW83_RS01125	COG0277	FAD linked oxidase domain protein
AXW83_RS01130	COG4178	(ABC) transporter
AXW83_RS01140	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AXW83_RS01145	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AXW83_RS01150	COG0124	histidyl-tRNA synthetase
AXW83_RS01165	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AXW83_RS01170	COG0277	FAD linked oxidase domain protein
AXW83_RS01175	COG2195	Cleaves the N-terminal amino acid of tripeptides
AXW83_RS01195	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AXW83_RS01205	COG0747	negative chemotaxis
AXW83_RS01210	COG0154	amidase activity
AXW83_RS01220	COG1741	Belongs to the pirin family
AXW83_RS01230	COG1722	exodeoxyribonuclease VII activity
AXW83_RS01235	COG1522	sequence-specific DNA binding
AXW83_RS01250	COG2205	protein histidine kinase activity
AXW83_RS01250	COG0784	Response regulator, receiver
AXW83_RS01255	COG1970	mechanosensitive ion channel activity
AXW83_RS01270	COG4166	transmembrane transport
AXW83_RS01285	COG0583	DNA-binding transcription factor activity
AXW83_RS01290	COG0459	protein refolding
AXW83_RS01295	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AXW83_RS01335	COG1376	ErfK ybiS ycfS ynhG family protein
AXW83_RS01345	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AXW83_RS01350	COG1388	LysM domain
AXW83_RS01350	COG1376	ErfK ybiS ycfS ynhG family protein
AXW83_RS01355	COG0840	transmembrane signaling receptor activity
AXW83_RS01365	COG0534	Mate efflux family protein
AXW83_RS01375	COG0747	negative chemotaxis
AXW83_RS01380	COG0601	transmembrane transport
AXW83_RS01385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW83_RS01410	COG3964	amidohydrolase
AXW83_RS01440	COG1396	sequence-specific DNA binding
AXW83_RS01455	COG0666	response to abiotic stimulus
AXW83_RS01465	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AXW83_RS01470	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AXW83_RS01475	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AXW83_RS01485	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AXW83_RS01505	COG0189	ligase activity
AXW83_RS01510	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AXW83_RS01515	COG1744	ABC transporter substrate-binding protein PnrA-like
AXW83_RS01520	COG3845	ABC transporter
AXW83_RS01525	COG1079	Belongs to the binding-protein-dependent transport system permease family
AXW83_RS01530	COG1079	Belongs to the binding-protein-dependent transport system permease family
AXW83_RS01555	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXW83_RS01570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW83_RS01580	COG0747	negative chemotaxis
AXW83_RS01585	COG3395	kinase activity
AXW83_RS01595	COG0318	PFAM AMP-dependent synthetase and ligase
AXW83_RS01615	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AXW83_RS01620	COG1127	ABC transporter
AXW83_RS01630	COG3218	ABC-type transport auxiliary lipoprotein component
AXW83_RS01630	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AXW83_RS01635	COG0789	Transcriptional regulator
AXW83_RS01655	COG0633	Ferredoxin
AXW83_RS01685	COG0776	regulation of translation
AXW83_RS01725	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXW83_RS01740	COG1079	Belongs to the binding-protein-dependent transport system permease family
AXW83_RS01745	COG4603	Belongs to the binding-protein-dependent transport system permease family
AXW83_RS01750	COG3845	ABC transporter
AXW83_RS01755	COG3608	succinylglutamate desuccinylase aspartoacylase
AXW83_RS01755	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AXW83_RS01760	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AXW83_RS01760	COG2080	2 iron, 2 sulfur cluster binding
AXW83_RS01770	COG0402	S-adenosylhomocysteine deaminase activity
AXW83_RS01775	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AXW83_RS01785	COG0280	phosphate acetyltransferase
AXW83_RS01785	COG0281	malic enzyme
AXW83_RS01810	COG2337	Toxic component of a toxin-antitoxin (TA) module
AXW83_RS01825	COG1703	isobutyryl-CoA mutase activity
AXW83_RS01850	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AXW83_RS01855	COG3842	ATPase activity
AXW83_RS01860	COG1176	ABC-type spermidine putrescine transport system, permease component I
AXW83_RS01865	COG1177	transmembrane transport
AXW83_RS01885	COG0351	phosphomethylpyrimidine kinase
AXW83_RS01895	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
AXW83_RS01910	COG0433	COG0433 Predicted ATPase
AXW83_RS01940	COG4695	Portal protein
AXW83_RS02030	COG4235	cytochrome complex assembly
AXW83_RS02035	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AXW83_RS02040	COG1138	Cytochrome C-type biogenesis protein
AXW83_RS02045	COG3088	subunit of a heme lyase
AXW83_RS02050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXW83_RS02055	COG0745	RESPONSE REGULATOR receiver
AXW83_RS02065	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AXW83_RS02070	COG2205	protein histidine kinase activity
AXW83_RS02070	COG2202	Pas domain
AXW83_RS02075	COG0308	aminopeptidase N
AXW83_RS02090	COG2017	converts alpha-aldose to the beta-anomer
AXW83_RS02095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXW83_RS02100	COG0829	nickel cation binding
AXW83_RS02110	COG0831	urea catabolic process
AXW83_RS02110	COG0832	Belongs to the urease beta subunit family
AXW83_RS02125	COG0804	urea catabolic process
AXW83_RS02135	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AXW83_RS02140	COG1733	regulation of RNA biosynthetic process
AXW83_RS02155	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AXW83_RS02160	COG0830	nickel cation binding
AXW83_RS02165	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AXW83_RS02175	COG3707	response regulator
AXW83_RS02180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXW83_RS02180	COG1116	anion transmembrane transporter activity
AXW83_RS02185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXW83_RS02190	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AXW83_RS02195	COG0243	molybdopterin cofactor binding
AXW83_RS02200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW83_RS02205	COG1116	anion transmembrane transporter activity
AXW83_RS02210	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AXW83_RS02215	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AXW83_RS02225	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AXW83_RS02250	COG5507	3-demethylubiquinone-9 3-methyltransferase
AXW83_RS02260	COG0730	response to heat
AXW83_RS02275	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AXW83_RS02280	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AXW83_RS02295	COG2202	Pas domain
AXW83_RS02295	COG2205	protein histidine kinase activity
AXW83_RS02320	COG1573	uracil-dna glycosylase
AXW83_RS02330	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AXW83_RS02335	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AXW83_RS02355	COG2814	Major facilitator Superfamily
AXW83_RS02365	COG4215	(ABC) transporter
AXW83_RS02375	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AXW83_RS02385	COG2084	Dehydrogenase
AXW83_RS02390	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXW83_RS02400	COG2814	Major facilitator Superfamily
AXW83_RS02415	COG0840	transmembrane signaling receptor activity
AXW83_RS02435	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AXW83_RS02450	COG1376	ErfK ybiS ycfS ynhG family protein
AXW83_RS02470	COG0546	phosphoglycolate phosphatase activity
AXW83_RS02485	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AXW83_RS02495	COG0531	amino acid
AXW83_RS02520	COG2226	methyltransferase
AXW83_RS02535	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AXW83_RS02550	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AXW83_RS02555	COG0477	Major facilitator Superfamily
AXW83_RS02570	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AXW83_RS02590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXW83_RS02595	COG3045	CreA protein
AXW83_RS02605	COG0215	cysteine-tRNA ligase activity
AXW83_RS02615	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AXW83_RS02625	COG5265	(ABC) transporter
AXW83_RS02635	COG4106	trans-aconitate 2-methyltransferase activity
AXW83_RS02640	COG0688	phosphatidylethanolamine metabolic process
AXW83_RS02645	COG1183	phosphatidylcholine synthase activity
AXW83_RS02655	COG0424	maF-like protein
AXW83_RS02670	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AXW83_RS02755	COG4957	zinc ion binding
AXW83_RS02870	COG0784	Response regulator, receiver
AXW83_RS02870	COG4191	Histidine kinase
AXW83_RS02925	COG0582	viral genome integration into host DNA
AXW83_RS02950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXW83_RS02965	COG0583	DNA-binding transcription factor activity
AXW83_RS02970	COG0583	DNA-binding transcription factor activity
AXW83_RS02980	COG3842	ATPase activity
AXW83_RS03000	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS03015	COG0405	Gamma-glutamyltransferase
AXW83_RS03040	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AXW83_RS03065	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AXW83_RS03070	COG2223	nitrite transmembrane transporter activity
AXW83_RS03075	COG0629	single-stranded DNA binding
AXW83_RS03080	COG0747	negative chemotaxis
AXW83_RS03095	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXW83_RS03100	COG2095	MarC family integral membrane protein
AXW83_RS03110	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AXW83_RS03130	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AXW83_RS03135	COG1840	ABC-type Fe3 transport system, periplasmic component
AXW83_RS03150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXW83_RS03170	COG0477	Major facilitator Superfamily
AXW83_RS03185	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AXW83_RS03195	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AXW83_RS03220	COG3550	peptidyl-serine autophosphorylation
AXW83_RS03230	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AXW83_RS03235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXW83_RS03255	COG1024	Enoyl-CoA hydratase
AXW83_RS03265	COG3842	ATPase activity
AXW83_RS03270	COG1176	ABC-type spermidine putrescine transport system, permease component I
AXW83_RS03275	COG0318	PFAM AMP-dependent synthetase and ligase
AXW83_RS03285	COG0747	negative chemotaxis
AXW83_RS03295	COG0318	PFAM AMP-dependent synthetase and ligase
AXW83_RS03300	COG1024	Enoyl-CoA hydratase
AXW83_RS03305	COG0318	PFAM AMP-dependent synthetase and ligase
AXW83_RS03310	COG0601	transmembrane transport
AXW83_RS03315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW83_RS03320	COG2706	6-phosphogluconolactonase activity
AXW83_RS03325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXW83_RS03330	COG0583	DNA-binding transcription factor activity
AXW83_RS03360	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AXW83_RS03365	COG1902	pentaerythritol trinitrate reductase activity
AXW83_RS03380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXW83_RS03410	COG0527	aspartate kinase activity
AXW83_RS03415	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AXW83_RS03425	COG0604	alcohol dehydrogenase
AXW83_RS03455	COG1360	Flagellar Motor Protein
AXW83_RS03460	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AXW83_RS03470	COG0737	Belongs to the 5'-nucleotidase family
AXW83_RS03490	COG0729	surface antigen
AXW83_RS03505	COG2885	chlorophyll binding
AXW83_RS03505	COG3047	cAMP biosynthetic process
AXW83_RS03510	COG0052	Belongs to the universal ribosomal protein uS2 family
AXW83_RS03525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXW83_RS03535	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AXW83_RS03540	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AXW83_RS03550	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AXW83_RS03560	COG0583	DNA-binding transcription factor activity
AXW83_RS03565	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AXW83_RS03570	COG0571	ribonuclease III activity
AXW83_RS03575	COG0681	Belongs to the peptidase S26 family
AXW83_RS03585	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AXW83_RS03590	COG0736	holo-[acyl-carrier-protein] synthase activity
AXW83_RS03605	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AXW83_RS03615	COG1758	RNA polymerase activity
AXW83_RS03625	COG1381	Involved in DNA repair and RecF pathway recombination
AXW83_RS03635	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AXW83_RS03655	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AXW83_RS03655	COG0473	3-isopropylmalate dehydrogenase activity
AXW83_RS03660	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AXW83_RS03670	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AXW83_RS03680	COG0113	porphobilinogen synthase activity
AXW83_RS03700	COG2989	Protein conserved in bacteria
AXW83_RS03725	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AXW83_RS03730	COG2814	Major facilitator Superfamily
AXW83_RS03735	COG0789	Transcriptional regulator
AXW83_RS03740	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AXW83_RS03755	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AXW83_RS03760	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AXW83_RS03760	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AXW83_RS03770	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AXW83_RS03780	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AXW83_RS03785	COG2814	Major facilitator Superfamily
AXW83_RS03790	COG3257	ureidoglycine aminohydrolase activity
AXW83_RS03795	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AXW83_RS03800	COG0697	spore germination
AXW83_RS03820	COG0416	fatty acid biosynthetic process
AXW83_RS03825	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AXW83_RS03830	COG0776	regulation of translation
AXW83_RS03845	COG3685	Protein conserved in bacteria
AXW83_RS03905	COG0726	polysaccharide deacetylase
AXW83_RS03915	COG1612	heme a metabolic process
AXW83_RS03935	COG1832	CoA-binding protein
AXW83_RS03940	COG1024	Enoyl-CoA hydratase
AXW83_RS03950	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AXW83_RS03955	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AXW83_RS03960	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS03980	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXW83_RS04000	COG0436	Aminotransferase
AXW83_RS04010	COG2226	methyltransferase
AXW83_RS04025	COG0667	Aldo Keto reductase
AXW83_RS04030	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AXW83_RS04050	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AXW83_RS04065	COG2925	Exonuclease
AXW83_RS04090	COG0785	Cytochrome C biogenesis protein
AXW83_RS04115	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AXW83_RS04140	COG0583	DNA-binding transcription factor activity
AXW83_RS04150	COG4948	Mandelate Racemase Muconate Lactonizing
AXW83_RS04155	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXW83_RS04165	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXW83_RS04165	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AXW83_RS04170	COG1414	Transcriptional regulator
AXW83_RS04175	COG1024	Enoyl-CoA hydratase
AXW83_RS04180	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AXW83_RS04185	COG2030	dehydratase
AXW83_RS04185	COG1012	belongs to the aldehyde dehydrogenase family
AXW83_RS04190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXW83_RS04195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW83_RS04200	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AXW83_RS04210	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS04220	COG1609	Transcriptional regulator
AXW83_RS04235	COG4974	Belongs to the 'phage' integrase family
AXW83_RS04240	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AXW83_RS04245	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AXW83_RS04265	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AXW83_RS04290	COG0625	glutathione transferase activity
AXW83_RS04295	COG0625	glutathione transferase activity
AXW83_RS04305	COG1309	transcriptional regulator
AXW83_RS04320	COG4941	Belongs to the sigma-70 factor family
AXW83_RS04325	COG3795	YCII-related domain
AXW83_RS04330	COG0583	DNA-binding transcription factor activity
AXW83_RS04355	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS04405	COG2169	Transcriptional regulator
AXW83_RS04405	COG1917	Cupin 2, conserved barrel domain protein
AXW83_RS04415	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AXW83_RS04470	COG0459	protein refolding
AXW83_RS04475	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AXW83_RS04515	COG0443	Heat shock 70 kDa protein
AXW83_RS04535	COG4716	Myosin-crossreactive antigen
AXW83_RS04540	COG2823	Periplasmic or secreted lipoprotein
AXW83_RS04560	COG1127	ABC transporter
AXW83_RS04575	COG0667	Aldo Keto reductase
AXW83_RS04585	COG1012	belongs to the aldehyde dehydrogenase family
AXW83_RS04605	COG1136	(ABC) transporter
AXW83_RS04610	COG4591	ABC-type transport system involved in lipoprotein release permease component
AXW83_RS04615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXW83_RS04630	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AXW83_RS04640	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AXW83_RS04640	COG0574	Belongs to the PEP-utilizing enzyme family
AXW83_RS04650	COG0674	pyruvate-flavodoxin oxidoreductase activity
AXW83_RS04650	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AXW83_RS04650	COG1013	pyruvate-flavodoxin oxidoreductase activity
AXW83_RS04650	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AXW83_RS04670	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AXW83_RS04685	COG1294	oxidase, subunit
AXW83_RS04690	COG1271	oxidase subunit
AXW83_RS04695	COG0589	response to stress
AXW83_RS04705	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AXW83_RS04720	COG3038	cytochrome b561
AXW83_RS04735	COG4456	Virulence-associated protein
AXW83_RS04750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXW83_RS04755	COG3618	amidohydrolase
AXW83_RS04800	COG2268	Band 7 protein
AXW83_RS04800	COG2268	Band 7 protein
AXW83_RS04805	COG5564	TIM-barrel signal transduction protein
AXW83_RS04810	COG5441	Belongs to the UPF0261 family
AXW83_RS04845	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AXW83_RS04845	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXW83_RS04855	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXW83_RS04865	COG0473	3-isopropylmalate dehydrogenase activity
AXW83_RS04885	COG0765	amino acid transport
AXW83_RS04890	COG1126	abc transporter atp-binding protein
AXW83_RS04915	COG3842	ATPase activity
AXW83_RS04920	COG0165	Argininosuccinate lyase
AXW83_RS04925	COG0395	ABC-type sugar transport system, permease component
AXW83_RS04930	COG1175	transmembrane transport
AXW83_RS04940	COG1609	Transcriptional regulator
AXW83_RS04945	COG1414	Transcriptional regulator
AXW83_RS04950	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS04960	COG0747	negative chemotaxis
AXW83_RS04970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW83_RS04980	COG0444	Belongs to the ABC transporter superfamily
AXW83_RS04985	COG4608	Belongs to the ABC transporter superfamily
AXW83_RS04995	COG1132	(ABC) transporter
AXW83_RS05035	COG0747	negative chemotaxis
AXW83_RS05040	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AXW83_RS05045	COG0765	amino acid transport
AXW83_RS05050	COG4597	amino acid ABC transporter
AXW83_RS05055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW83_RS05065	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AXW83_RS05075	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AXW83_RS05085	COG4456	Virulence-associated protein
AXW83_RS05095	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXW83_RS05100	COG1116	anion transmembrane transporter activity
AXW83_RS05105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW83_RS05110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXW83_RS05115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXW83_RS05130	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AXW83_RS05140	COG0633	Ferredoxin
AXW83_RS05160	COG0175	sulfate reduction
AXW83_RS05170	COG1136	(ABC) transporter
AXW83_RS05180	COG1785	Belongs to the alkaline phosphatase family
AXW83_RS05185	COG1982	Orn Lys Arg decarboxylase major
AXW83_RS05190	COG1247	-acetyltransferase
AXW83_RS05195	COG2326	polyphosphate kinase activity
AXW83_RS05215	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS05220	COG4689	acetoacetate decarboxylase
AXW83_RS05235	COG1609	Transcriptional regulator
AXW83_RS05245	COG1175	transmembrane transport
AXW83_RS05250	COG0395	ABC-type sugar transport system, permease component
AXW83_RS05285	COG0366	Alpha amylase catalytic
AXW83_RS05290	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AXW83_RS05300	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AXW83_RS05310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW83_RS05320	COG0747	negative chemotaxis
AXW83_RS05330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXW83_RS05335	COG0747	negative chemotaxis
AXW83_RS05355	COG4172	Belongs to the ABC transporter superfamily
AXW83_RS05360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW83_RS05370	COG0747	negative chemotaxis
AXW83_RS05380	COG2072	flavoprotein involved in K transport
AXW83_RS05395	COG0848	biopolymer transport protein
AXW83_RS05405	COG0129	dihydroxy-acid dehydratase activity
AXW83_RS05440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW83_RS05445	COG4608	Belongs to the ABC transporter superfamily
AXW83_RS05450	COG0444	Belongs to the ABC transporter superfamily
AXW83_RS05475	COG1024	Enoyl-CoA hydratase
AXW83_RS05485	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS05500	COG0346	lactoylglutathione lyase activity
AXW83_RS05505	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AXW83_RS05520	COG0540	Belongs to the ATCase OTCase family
AXW83_RS05525	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AXW83_RS05530	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AXW83_RS05535	COG0758	DNA mediated transformation
AXW83_RS05555	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AXW83_RS05580	COG2855	membrane
AXW83_RS05585	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXW83_RS05590	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AXW83_RS05595	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AXW83_RS05600	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AXW83_RS05610	COG0154	amidase activity
AXW83_RS05630	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AXW83_RS05650	COG0625	glutathione transferase activity
AXW83_RS05670	COG0105	UTP biosynthetic process
AXW83_RS05680	COG0243	molybdopterin cofactor binding
AXW83_RS05700	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AXW83_RS05705	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AXW83_RS05710	COG0628	permease
AXW83_RS05725	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AXW83_RS05730	COG0248	Ppx GppA phosphatase
AXW83_RS05735	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AXW83_RS05740	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AXW83_RS05760	COG0110	maltose O-acetyltransferase activity
AXW83_RS05800	COG0463	Glycosyl transferase, family 2
AXW83_RS05810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW83_RS05815	COG0626	cystathionine gamma-synthase activity
AXW83_RS05820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW83_RS05825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW83_RS05830	COG4597	amino acid ABC transporter
AXW83_RS05835	COG0765	amino acid transport
AXW83_RS05840	COG1126	abc transporter atp-binding protein
AXW83_RS05850	COG0584	glycerophosphoryl diester phosphodiesterase
AXW83_RS05860	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AXW83_RS05860	COG0519	Catalyzes the synthesis of GMP from XMP
AXW83_RS05865	COG2226	methyltransferase
AXW83_RS05875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXW83_RS05885	COG1393	Belongs to the ArsC family
AXW83_RS05895	COG0343	queuine tRNA-ribosyltransferase activity
AXW83_RS05915	COG0148	phosphopyruvate hydratase activity
AXW83_RS05925	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AXW83_RS05930	COG2814	Major facilitator Superfamily
AXW83_RS05935	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AXW83_RS05940	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AXW83_RS05965	COG0537	adenosine 5'-monophosphoramidase activity
AXW83_RS05990	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AXW83_RS06000	COG0784	Response regulator, receiver
AXW83_RS06030	COG0557	exoribonuclease II activity
AXW83_RS06060	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AXW83_RS06065	COG3265	gluconokinase activity
AXW83_RS06075	COG2132	Multicopper oxidase
AXW83_RS06085	COG0544	peptidyl-prolyl cis-trans isomerase activity
AXW83_RS06090	COG0740	serine-type endopeptidase activity
AXW83_RS06095	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AXW83_RS06100	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AXW83_RS06150	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AXW83_RS06160	COG2925	Exonuclease
AXW83_RS06180	COG0129	dihydroxy-acid dehydratase activity
AXW83_RS06185	COG0583	DNA-binding transcription factor activity
AXW83_RS06190	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AXW83_RS06205	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AXW83_RS06220	COG0747	negative chemotaxis
AXW83_RS06230	COG0583	DNA-binding transcription factor activity
AXW83_RS06255	COG0601	transmembrane transport
AXW83_RS06280	COG1012	belongs to the aldehyde dehydrogenase family
AXW83_RS06285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXW83_RS06290	COG2267	carboxylic ester hydrolase activity
AXW83_RS06305	COG4176	ABC-type proline glycine betaine transport system permease component
AXW83_RS06315	COG0583	DNA-binding transcription factor activity
AXW83_RS06420	COG1335	isochorismatase
AXW83_RS06435	COG4566	intracellular signal transduction
AXW83_RS06440	COG4566	intracellular signal transduction
AXW83_RS06445	COG4191	Histidine kinase
AXW83_RS06465	COG3321	synthase
AXW83_RS06465	COG0604	alcohol dehydrogenase
AXW83_RS06465	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS06470	COG0625	glutathione transferase activity
AXW83_RS06475	COG0400	carboxylic ester hydrolase activity
AXW83_RS06485	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS06510	COG2207	Transcriptional regulator
AXW83_RS06525	COG3631	Ketosteroid isomerase-related protein
AXW83_RS06530	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS06540	COG1012	belongs to the aldehyde dehydrogenase family
AXW83_RS06555	COG4221	oxidoreductase activity
AXW83_RS06610	COG1012	belongs to the aldehyde dehydrogenase family
AXW83_RS06620	COG0583	DNA-binding transcription factor activity
AXW83_RS06625	COG0251	oxidation-reduction process
AXW83_RS06635	COG1505	serine-type exopeptidase activity
AXW83_RS06640	COG0024	Methionine aminopeptidase
AXW83_RS06655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXW83_RS06670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW83_RS06685	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS06690	COG0583	DNA-binding transcription factor activity
AXW83_RS06710	COG0395	ABC-type sugar transport system, permease component
AXW83_RS06730	COG1070	Carbohydrate kinase
AXW83_RS06740	COG0129	dihydroxy-acid dehydratase activity
AXW83_RS06755	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXW83_RS06760	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXW83_RS06765	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXW83_RS06770	COG0649	NAD binding
AXW83_RS06775	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AXW83_RS06780	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AXW83_RS06790	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AXW83_RS06800	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXW83_RS06810	COG0713	ATP synthesis coupled electron transport
AXW83_RS06825	COG1007	ATP synthesis coupled electron transport
AXW83_RS06840	COG0346	lactoylglutathione lyase activity
AXW83_RS06870	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AXW83_RS06880	COG1160	GTP binding
AXW83_RS06885	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS06890	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AXW83_RS06905	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AXW83_RS06910	COG0305	Participates in initiation and elongation during chromosome replication
AXW83_RS06920	COG1487	ribonuclease activity
AXW83_RS06925	COG0359	binds to the 23S rRNA
AXW83_RS06935	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AXW83_RS06940	COG0360	Binds together with S18 to 16S ribosomal RNA
AXW83_RS06945	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AXW83_RS06955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AXW83_RS06960	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AXW83_RS06965	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AXW83_RS06970	COG1561	YicC-like family, N-terminal region
AXW83_RS06975	COG0194	GDP metabolic process
AXW83_RS06980	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AXW83_RS06985	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AXW83_RS06990	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AXW83_RS07005	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AXW83_RS07020	COG0488	(ABC) transporter
AXW83_RS07025	COG0840	transmembrane signaling receptor activity
AXW83_RS07030	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AXW83_RS07035	COG0442	prolyl-tRNA aminoacylation
AXW83_RS07045	COG1136	(ABC) transporter
AXW83_RS07060	COG1335	isochorismatase
AXW83_RS07065	COG0154	amidase activity
AXW83_RS07070	COG0052	Belongs to the universal ribosomal protein uS2 family
AXW83_RS07075	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AXW83_RS07080	COG0528	UMP kinase activity
AXW83_RS07085	COG0233	cytoplasmic translational termination
AXW83_RS07090	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AXW83_RS07100	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AXW83_RS07105	COG0750	zinc metalloprotease
AXW83_RS07110	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AXW83_RS07115	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AXW83_RS07120	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AXW83_RS07125	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AXW83_RS07130	COG3494	Protein of unknown function (DUF1009)
AXW83_RS07135	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AXW83_RS07150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AXW83_RS07160	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AXW83_RS07165	COG0303	'Molybdopterin
AXW83_RS07170	COG0315	cyclic pyranopterin monophosphate synthase activity
AXW83_RS07180	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AXW83_RS07190	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AXW83_RS07195	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AXW83_RS07200	COG0149	triose-phosphate isomerase activity
AXW83_RS07210	COG0504	CTP synthase activity
AXW83_RS07235	COG0754	glutathionylspermidine amidase activity
AXW83_RS07245	COG2943	transferase activity, transferring hexosyl groups
AXW83_RS07250	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AXW83_RS07255	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AXW83_RS07260	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AXW83_RS07265	COG2832	Protein of unknown function (DUF454)
AXW83_RS07295	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AXW83_RS07305	COG4166	transmembrane transport
AXW83_RS07320	COG2301	Belongs to the HpcH HpaI aldolase family
AXW83_RS07325	COG0679	Auxin Efflux Carrier
AXW83_RS07330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXW83_RS07335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXW83_RS07355	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AXW83_RS07360	COG2897	thiosulfate sulfurtransferase activity
AXW83_RS07370	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AXW83_RS07375	COG4208	sulfate ABC transporter
AXW83_RS07380	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AXW83_RS07390	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AXW83_RS07390	COG1648	precorrin-2 dehydrogenase activity
AXW83_RS07400	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS07420	COG1686	Belongs to the peptidase S11 family
AXW83_RS07425	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AXW83_RS07435	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXW83_RS07440	COG0084	hydrolase, TatD family'
AXW83_RS07445	COG0321	lipoyl(octanoyl) transferase activity
AXW83_RS07445	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AXW83_RS07460	COG2137	regulation of response to DNA damage stimulus
AXW83_RS07470	COG3956	TIGRFAM MazG family protein
AXW83_RS07475	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AXW83_RS07480	COG1923	regulation of RNA biosynthetic process
AXW83_RS07485	COG2204	response regulator
AXW83_RS07490	COG5000	phosphorelay sensor kinase activity
AXW83_RS07495	COG2204	response regulator
AXW83_RS07510	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AXW83_RS07510	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AXW83_RS07515	COG1546	Belongs to the CinA family
AXW83_RS07515	COG1058	Belongs to the CinA family
AXW83_RS07525	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AXW83_RS07540	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AXW83_RS07545	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXW83_RS07555	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXW83_RS07560	COG0022	dehydrogenase e1 component
AXW83_RS07560	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXW83_RS07565	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AXW83_RS07570	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AXW83_RS07600	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AXW83_RS07600	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AXW83_RS07605	COG0347	Belongs to the P(II) protein family
AXW83_RS07610	COG0174	glutamine synthetase
AXW83_RS07625	COG0187	DNA topoisomerase II activity
AXW83_RS07640	COG0513	Belongs to the DEAD box helicase family
AXW83_RS07645	COG3706	GGDEF domain
AXW83_RS07645	COG5001	Diguanylate cyclase
AXW83_RS07645	COG4251	negative regulation of phosphorylation
AXW83_RS07645	COG2203	Gaf domain
AXW83_RS07660	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AXW83_RS07665	COG0525	valine-tRNA ligase activity
AXW83_RS07690	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AXW83_RS07720	COG0415	Belongs to the DNA photolyase family
AXW83_RS07725	COG4221	oxidoreductase activity
AXW83_RS07730	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AXW83_RS07735	COG2897	thiosulfate sulfurtransferase activity
AXW83_RS07745	COG1473	amidohydrolase
AXW83_RS07765	COG1846	Transcriptional regulator
AXW83_RS07795	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXW83_RS07800	COG0683	leucine binding
AXW83_RS07805	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AXW83_RS07815	COG3737	Protein of unknown function (DUF498/DUF598)
AXW83_RS07825	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AXW83_RS07830	COG1862	Preprotein translocase
AXW83_RS07845	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AXW83_RS07850	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AXW83_RS07855	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AXW83_RS07865	COG0805	protein transport
AXW83_RS07870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AXW83_RS07875	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AXW83_RS07880	COG3842	ATPase activity
AXW83_RS07885	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AXW83_RS07890	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AXW83_RS07900	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AXW83_RS07910	COG0018	arginyl-trna synthetase
AXW83_RS07915	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AXW83_RS07920	COG0316	Belongs to the HesB IscA family
AXW83_RS07925	COG1278	Cold shock
AXW83_RS07930	COG1280	lysine exporter protein (LysE YggA)
AXW83_RS07935	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AXW83_RS07940	COG0436	Aminotransferase
AXW83_RS07950	COG2721	sulfolactate sulfo-lyase activity
AXW83_RS07960	COG1686	Belongs to the peptidase S11 family
AXW83_RS07965	COG0484	heat shock protein binding
AXW83_RS07975	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AXW83_RS07985	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS08005	COG2151	metal-sulfur cluster biosynthetic enzyme
AXW83_RS08010	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AXW83_RS08015	COG0719	Fe-S assembly protein
AXW83_RS08020	COG0396	ATPase activity
AXW83_RS08025	COG0719	Fe-S assembly protein
AXW83_RS08035	COG2945	thiolester hydrolase activity
AXW83_RS08040	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AXW83_RS08050	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AXW83_RS08055	COG0739	heme binding
AXW83_RS08065	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AXW83_RS08070	COG0860	N-Acetylmuramoyl-L-alanine amidase
AXW83_RS08075	COG1530	ribonuclease E activity
AXW83_RS08085	COG0668	transmembrane transport
AXW83_RS08090	COG0436	Aminotransferase
AXW83_RS08095	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AXW83_RS08095	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AXW83_RS08100	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AXW83_RS08105	COG0511	ligase activity, forming carbon-carbon bonds
AXW83_RS08115	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AXW83_RS08140	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AXW83_RS08175	COG0297	glycogen (starch) synthase activity
AXW83_RS08185	COG1082	Xylose isomerase domain protein TIM barrel
AXW83_RS08185	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AXW83_RS08190	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AXW83_RS08200	COG1126	abc transporter atp-binding protein
AXW83_RS08205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW83_RS08210	COG0765	amino acid transport
AXW83_RS08225	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AXW83_RS08230	COG1802	Transcriptional regulator
AXW83_RS08235	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AXW83_RS08240	COG3485	protocatechuate 3,4-dioxygenase
AXW83_RS08245	COG3485	protocatechuate 3,4-dioxygenase
AXW83_RS08260	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AXW83_RS08265	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXW83_RS08270	COG0583	DNA-binding transcription factor activity
AXW83_RS08280	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AXW83_RS08305	COG0683	leucine binding
AXW83_RS08315	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AXW83_RS08335	COG0583	DNA-binding transcription factor activity
AXW83_RS08340	COG1162	GTPase activity
AXW83_RS08385	COG0129	dihydroxy-acid dehydratase activity
AXW83_RS08395	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS08405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AXW83_RS08410	COG0321	lipoyl(octanoyl) transferase activity
AXW83_RS08415	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AXW83_RS08425	COG2239	Acts as a magnesium transporter
AXW83_RS08435	COG0546	phosphoglycolate phosphatase activity
AXW83_RS08445	COG0564	pseudouridine synthase activity
AXW83_RS08450	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AXW83_RS08455	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AXW83_RS08460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXW83_RS08480	COG0203	ribosomal protein L17
AXW83_RS08485	COG0202	RNA polymerase activity
AXW83_RS08490	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AXW83_RS08495	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AXW83_RS08505	COG0563	adenylate kinase activity
AXW83_RS08510	COG0201	protein transport
AXW83_RS08515	COG0200	Binds to the 23S rRNA
AXW83_RS08520	COG1841	ribosomal large subunit assembly
AXW83_RS08525	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AXW83_RS08535	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AXW83_RS08540	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AXW83_RS08545	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AXW83_RS08550	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AXW83_RS08555	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AXW83_RS08560	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AXW83_RS08565	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AXW83_RS08570	COG0255	Belongs to the universal ribosomal protein uL29 family
AXW83_RS08575	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AXW83_RS08580	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AXW83_RS08585	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AXW83_RS08590	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AXW83_RS08595	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AXW83_RS08600	COG0089	rRNA binding
AXW83_RS08605	COG0088	Forms part of the polypeptide exit tunnel
AXW83_RS08610	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AXW83_RS08615	COG0051	transcription antitermination factor activity, RNA binding
AXW83_RS08620	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AXW83_RS08625	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AXW83_RS08630	COG0049	tRNA binding
AXW83_RS08635	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AXW83_RS08640	COG1132	(ABC) transporter
AXW83_RS08645	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AXW83_RS08650	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AXW83_RS08655	COG0085	RNA polymerase activity
AXW83_RS08665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AXW83_RS08670	COG0081	regulation of translation
AXW83_RS08675	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AXW83_RS08710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AXW83_RS08715	COG3093	addiction module antidote protein HigA
AXW83_RS08725	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AXW83_RS08730	COG0725	ABC transporter, periplasmic molybdate-binding protein
AXW83_RS08735	COG4149	molybdate abc transporter
AXW83_RS08740	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AXW83_RS08750	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AXW83_RS08750	COG2010	Cytochrome c
AXW83_RS08755	COG2080	2 iron, 2 sulfur cluster binding
AXW83_RS08765	COG4948	Mandelate Racemase Muconate Lactonizing
AXW83_RS08770	COG4948	Mandelate Racemase Muconate Lactonizing
AXW83_RS08775	COG4172	Belongs to the ABC transporter superfamily
AXW83_RS08780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW83_RS08785	COG0601	transmembrane transport
AXW83_RS08790	COG0747	negative chemotaxis
AXW83_RS08805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXW83_RS08810	COG4948	Mandelate Racemase Muconate Lactonizing
AXW83_RS08820	COG0747	negative chemotaxis
AXW83_RS08825	COG0747	negative chemotaxis
AXW83_RS08835	COG4608	Belongs to the ABC transporter superfamily
AXW83_RS08840	COG0601	transmembrane transport
AXW83_RS08860	COG3181	Tripartite tricarboxylate transporter family receptor
AXW83_RS08865	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXW83_RS08870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXW83_RS08905	COG0028	Belongs to the TPP enzyme family
AXW83_RS08940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AXW83_RS08950	COG0477	Major facilitator Superfamily
AXW83_RS09000	COG2301	Belongs to the HpcH HpaI aldolase family
AXW83_RS09020	COG0778	Nitroreductase
AXW83_RS09050	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AXW83_RS09055	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AXW83_RS09070	COG1487	ribonuclease activity
AXW83_RS09080	COG0302	gtp cyclohydrolase
AXW83_RS09085	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AXW83_RS09090	COG1752	Esterase of the alpha-beta hydrolase superfamily
AXW83_RS09140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AXW83_RS09155	COG0583	DNA-binding transcription factor activity
AXW83_RS09200	COG1253	flavin adenine dinucleotide binding
AXW83_RS09230	COG0625	glutathione transferase activity
AXW83_RS09240	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AXW83_RS09245	COG1546	Belongs to the CinA family
AXW83_RS09245	COG1058	Belongs to the CinA family
AXW83_RS09255	COG1058	Belongs to the CinA family
AXW83_RS09255	COG1546	Belongs to the CinA family
AXW83_RS09260	COG0024	Methionine aminopeptidase
AXW83_RS09265	COG2003	Belongs to the UPF0758 family
AXW83_RS09270	COG2308	Evidence 4 Homologs of previously reported genes of
AXW83_RS09280	COG1305	Transglutaminase-like
AXW83_RS09300	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AXW83_RS09305	COG5425	PFAM Usg family protein
AXW83_RS09315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW83_RS09320	COG1376	ErfK ybiS ycfS ynhG family protein
AXW83_RS09330	COG2068	MobA-Related Protein
AXW83_RS09335	COG3608	succinylglutamate desuccinylase aspartoacylase
AXW83_RS09335	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AXW83_RS09385	COG0840	transmembrane signaling receptor activity
AXW83_RS09425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXW83_RS09430	COG3938	Belongs to the proline racemase family
AXW83_RS09435	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXW83_RS09460	COG0683	leucine binding
AXW83_RS09470	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AXW83_RS09480	COG0625	glutathione transferase activity
AXW83_RS09490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXW83_RS09500	COG0840	transmembrane signaling receptor activity
AXW83_RS09540	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AXW83_RS09570	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AXW83_RS09580	COG1696	Membrane protein involved in D-alanine export
AXW83_RS09610	COG4786	Flagellar basal body rod
AXW83_RS09615	COG4786	Flagellar basal body rod
AXW83_RS09645	COG1338	Plays a role in the flagellum-specific transport system
AXW83_RS09660	COG1558	bacterial-type flagellum-dependent cell motility
AXW83_RS09665	COG1677	Flagellar hook-basal body complex protein FliE
AXW83_RS09670	COG1987	bacterial-type flagellum assembly
AXW83_RS09675	COG1684	flagellar biosynthetic protein fliR
AXW83_RS09680	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AXW83_RS09690	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AXW83_RS09695	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AXW83_RS09705	COG3685	Protein conserved in bacteria
AXW83_RS09710	COG0538	isocitrate dehydrogenase activity
AXW83_RS09720	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS09735	COG1706	bacterial-type flagellum-dependent cell motility
AXW83_RS09740	COG3951	Flagellar rod assembly protein muramidase FlgJ
AXW83_RS09770	COG5443	negative regulation of bacterial-type flagellum assembly
AXW83_RS09795	COG3768	UPF0283 membrane protein
AXW83_RS09800	COG3106	COG3106 Predicted ATPase
AXW83_RS09810	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AXW83_RS09820	COG0438	transferase activity, transferring glycosyl groups
AXW83_RS09830	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS09840	COG1396	sequence-specific DNA binding
AXW83_RS09845	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AXW83_RS09845	COG2010	Cytochrome c
AXW83_RS09880	COG0492	ferredoxin-NADP+ reductase activity
AXW83_RS09895	COG2351	hydroxyisourate hydrolase activity
AXW83_RS09900	COG3195	allantoin biosynthetic process
AXW83_RS09900	COG3648	Uricase
AXW83_RS09905	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS09930	COG0058	SHG alpha-glucan phosphorylase activity
AXW83_RS09945	COG0297	glycogen (starch) synthase activity
AXW83_RS09960	COG1640	4-alpha-glucanotransferase
AXW83_RS09985	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AXW83_RS10000	COG0339	signal peptide processing
AXW83_RS10010	COG0384	phenazine biosynthesis protein PhzF
AXW83_RS10020	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AXW83_RS10025	COG0251	oxidation-reduction process
AXW83_RS10030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXW83_RS10035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW83_RS10065	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AXW83_RS10070	COG1309	transcriptional regulator
AXW83_RS10090	COG0625	glutathione transferase activity
AXW83_RS10095	COG1794	racemase activity, acting on amino acids and derivatives
AXW83_RS10100	COG0028	Belongs to the TPP enzyme family
AXW83_RS10105	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AXW83_RS10110	COG0560	Phosphoserine phosphatase
AXW83_RS10110	COG3830	Belongs to the UPF0237 family
AXW83_RS10130	COG0330	HflC and HflK could
AXW83_RS10135	COG0330	HflC and HflK could
AXW83_RS10175	COG0114	fumarate hydratase activity
AXW83_RS10195	COG0277	FAD linked oxidase domain protein
AXW83_RS10205	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AXW83_RS10220	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXW83_RS10225	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXW83_RS10240	COG1598	PFAM Uncharacterised protein family UPF0150
AXW83_RS10245	COG1733	regulation of RNA biosynthetic process
AXW83_RS10250	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
AXW83_RS10260	COG2264	protein methyltransferase activity
AXW83_RS10270	COG0006	proline dipeptidase activity
AXW83_RS10270	COG0006	proline dipeptidase activity
AXW83_RS10280	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AXW83_RS10285	COG1917	Cupin 2, conserved barrel domain protein
AXW83_RS10285	COG2207	Transcriptional regulator
AXW83_RS10295	COG2207	Transcriptional regulator
AXW83_RS10305	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AXW83_RS10320	COG0659	secondary active sulfate transmembrane transporter activity
AXW83_RS10325	COG0497	DNA recombination
AXW83_RS10330	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AXW83_RS10340	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AXW83_RS10345	COG0849	cell division
AXW83_RS10350	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AXW83_RS10355	COG1181	Belongs to the D-alanine--D-alanine ligase family
AXW83_RS10370	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AXW83_RS10375	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AXW83_RS10380	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AXW83_RS10395	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AXW83_RS10400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AXW83_RS10410	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AXW83_RS10430	COG2001	Belongs to the MraZ family
AXW83_RS10435	COG1846	Transcriptional regulator
AXW83_RS10440	COG1764	response to oxidative stress
AXW83_RS10455	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AXW83_RS10460	COG3023	N-Acetylmuramoyl-L-alanine amidase
AXW83_RS10475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXW83_RS10480	COG1136	(ABC) transporter
AXW83_RS10485	COG1136	(ABC) transporter
AXW83_RS10485	COG0577	efflux transmembrane transporter activity
AXW83_RS10490	COG5001	Diguanylate cyclase
AXW83_RS10490	COG3300	MHYT domain
AXW83_RS10500	COG1283	sodium-dependent phosphate transmembrane transporter activity
AXW83_RS10510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AXW83_RS10515	COG0456	acetyltransferase
AXW83_RS10520	COG2824	Alkylphosphonate utilization operon protein PhnA
AXW83_RS10545	COG0697	spore germination
AXW83_RS10555	COG1278	Cold shock
AXW83_RS10560	COG1472	Belongs to the glycosyl hydrolase 3 family
AXW83_RS10590	COG0583	DNA-binding transcription factor activity
AXW83_RS10605	COG0667	Aldo Keto reductase
AXW83_RS10615	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AXW83_RS10625	COG0521	Mo-molybdopterin cofactor biosynthetic process
AXW83_RS10630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXW83_RS10645	COG2201	protein-glutamate methylesterase activity
AXW83_RS10650	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AXW83_RS10655	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AXW83_RS10660	COG0840	transmembrane signaling receptor activity
AXW83_RS10665	COG0835	chemotaxis
AXW83_RS10670	COG2198	Histidine kinase
AXW83_RS10670	COG0643	Histidine kinase
AXW83_RS10695	COG0697	spore germination
AXW83_RS10710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW83_RS10725	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AXW83_RS10750	COG1335	isochorismatase
AXW83_RS10760	COG1802	Transcriptional regulator
AXW83_RS10770	COG4172	Belongs to the ABC transporter superfamily
AXW83_RS10775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW83_RS10780	COG0601	transmembrane transport
AXW83_RS10800	COG0747	negative chemotaxis
AXW83_RS10810	COG0840	transmembrane signaling receptor activity
AXW83_RS10825	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AXW83_RS10840	COG0432	Pfam Uncharacterised protein family UPF0047
AXW83_RS10845	COG1280	lysine exporter protein (LysE YggA)
AXW83_RS10860	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AXW83_RS10875	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
AXW83_RS10885	COG0505	Belongs to the CarA family
AXW83_RS10895	COG0488	(ABC) transporter
AXW83_RS10920	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AXW83_RS10940	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AXW83_RS10945	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AXW83_RS10950	COG2095	MarC family integral membrane protein
AXW83_RS10965	COG1522	sequence-specific DNA binding
AXW83_RS10980	COG0583	DNA-binding transcription factor activity
AXW83_RS10995	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AXW83_RS11000	COG0473	3-isopropylmalate dehydrogenase activity
AXW83_RS11005	COG2184	nucleotidyltransferase activity
AXW83_RS11015	COG0747	negative chemotaxis
AXW83_RS11030	COG2002	toxin-antitoxin pair type II binding
AXW83_RS11035	COG2951	lytic endotransglycosylase activity
AXW83_RS11060	COG2133	pyrroloquinoline quinone binding
AXW83_RS11075	COG1671	Belongs to the UPF0178 family
AXW83_RS11100	COG0436	Aminotransferase
AXW83_RS11105	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AXW83_RS11110	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AXW83_RS11125	COG1280	lysine exporter protein (LysE YggA)
AXW83_RS11145	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AXW83_RS11160	COG0228	four-way junction DNA binding
AXW83_RS11165	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AXW83_RS11175	COG0336	Belongs to the RNA methyltransferase TrmD family
AXW83_RS11180	COG3744	PilT protein domain protein
AXW83_RS11205	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS11210	COG0335	large ribosomal subunit rRNA binding
AXW83_RS11220	COG3668	Plasmid stabilization system
AXW83_RS11230	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AXW83_RS11245	COG1280	lysine exporter protein (LysE YggA)
AXW83_RS11260	COG0066	3-isopropylmalate dehydratase activity
AXW83_RS11295	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AXW83_RS11375	COG0640	Transcriptional regulator
AXW83_RS11380	COG0697	spore germination
AXW83_RS11395	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AXW83_RS11400	COG0625	glutathione transferase activity
AXW83_RS11405	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AXW83_RS11410	COG0463	Glycosyl transferase, family 2
AXW83_RS11415	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS11430	COG3609	addiction module antidote protein, CC2985 family
AXW83_RS11440	COG1496	oxidoreductase activity
AXW83_RS11450	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AXW83_RS11455	COG4691	Plasmid stability protein
AXW83_RS11470	COG0322	excinuclease ABC activity
AXW83_RS11475	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AXW83_RS11485	COG0314	molybdopterin synthase activity
AXW83_RS11500	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AXW83_RS11505	COG1846	Transcriptional regulator
AXW83_RS11510	COG0745	RESPONSE REGULATOR receiver
AXW83_RS11515	COG2205	protein histidine kinase activity
AXW83_RS11525	COG0625	glutathione transferase activity
AXW83_RS11535	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXW83_RS11565	COG0006	proline dipeptidase activity
AXW83_RS11575	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AXW83_RS11580	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AXW83_RS11590	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AXW83_RS11595	COG0193	aminoacyl-tRNA hydrolase activity
AXW83_RS11615	COG0012	GTP binding
AXW83_RS11630	COG0235	Class ii aldolase
AXW83_RS11635	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AXW83_RS11645	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AXW83_RS11655	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AXW83_RS11655	COG2857	Cytochrome c1
AXW83_RS11665	COG0723	plastoquinol--plastocyanin reductase activity
AXW83_RS11670	COG1132	(ABC) transporter
AXW83_RS11675	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AXW83_RS11680	COG0408	coproporphyrinogen oxidase activity
AXW83_RS11685	COG0617	tRNA 3'-terminal CCA addition
AXW83_RS11695	COG0494	nUDIX hydrolase
AXW83_RS11705	COG0714	Associated with various cellular activities
AXW83_RS11750	COG0488	(ABC) transporter
AXW83_RS11760	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AXW83_RS11765	COG0837	glucose binding
AXW83_RS11770	COG3622	Belongs to the hyi family
AXW83_RS11840	COG3437	response regulator, receiver
AXW83_RS11850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXW83_RS11880	COG2198	Histidine kinase
AXW83_RS11880	COG0643	Histidine kinase
AXW83_RS11880	COG0784	Response regulator, receiver
AXW83_RS11890	COG2201	protein-glutamate methylesterase activity
AXW83_RS11895	COG2201	protein-glutamate methylesterase activity
AXW83_RS11905	COG0745	RESPONSE REGULATOR receiver
AXW83_RS11940	COG0392	lysyltransferase activity
AXW83_RS11945	COG0697	spore germination
AXW83_RS11960	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AXW83_RS11970	COG2271	Major facilitator Superfamily
AXW83_RS11980	COG2204	response regulator
AXW83_RS11985	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AXW83_RS11995	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AXW83_RS12000	COG1766	The M ring may be actively involved in energy transduction
AXW83_RS12020	COG0482	sulfurtransferase activity
AXW83_RS12145	COG0784	Response regulator, receiver
AXW83_RS12145	COG4191	Histidine kinase
AXW83_RS12150	COG0784	Response regulator, receiver
AXW83_RS12240	COG4957	zinc ion binding
AXW83_RS12300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW83_RS12305	COG0765	amino acid transport
AXW83_RS12330	COG0583	DNA-binding transcription factor activity
AXW83_RS12335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AXW83_RS12340	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXW83_RS12350	COG1522	sequence-specific DNA binding
AXW83_RS12370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW83_RS12375	COG0601	transmembrane transport
AXW83_RS12380	COG4533	DNA binding
AXW83_RS12385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXW83_RS12390	COG2186	Transcriptional regulator
AXW83_RS12440	COG3842	ATPase activity
AXW83_RS12450	COG1175	transmembrane transport
AXW83_RS12460	COG0129	dihydroxy-acid dehydratase activity
AXW83_RS12480	COG0583	DNA-binding transcription factor activity
AXW83_RS12485	COG0346	lactoylglutathione lyase activity
AXW83_RS12500	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AXW83_RS12515	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AXW83_RS12515	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AXW83_RS12525	COG0783	Belongs to the Dps family
AXW83_RS12530	COG4191	Histidine kinase
AXW83_RS12535	COG4566	intracellular signal transduction
AXW83_RS12540	COG0745	RESPONSE REGULATOR receiver
AXW83_RS12565	COG0840	transmembrane signaling receptor activity
AXW83_RS12575	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AXW83_RS12585	COG1802	Transcriptional regulator
AXW83_RS12590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXW83_RS12600	COG0747	negative chemotaxis
AXW83_RS12645	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AXW83_RS12650	COG1091	dTDP-4-dehydrorhamnose reductase activity
AXW83_RS12655	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AXW83_RS12665	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AXW83_RS12670	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AXW83_RS12685	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AXW83_RS12685	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AXW83_RS12700	COG0123	including yeast histone deacetylase and acetoin utilization protein
AXW83_RS12705	COG1376	ErfK ybiS ycfS ynhG family protein
AXW83_RS12710	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AXW83_RS12725	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AXW83_RS12740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXW83_RS12745	COG1268	BioY protein
AXW83_RS12805	COG2202	Pas domain
AXW83_RS12805	COG3920	Histidine kinase
AXW83_RS12835	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AXW83_RS12860	COG3920	Histidine kinase
AXW83_RS12875	COG1295	ribonuclease BN
AXW83_RS12905	COG0628	permease
AXW83_RS12940	COG0598	Magnesium transport protein CorA
AXW83_RS12970	COG4191	Histidine kinase
AXW83_RS12970	COG0784	Response regulator, receiver
AXW83_RS13015	COG2186	Transcriptional regulator
AXW83_RS13020	COG2084	Dehydrogenase
AXW83_RS13025	COG0765	amino acid transport
AXW83_RS13030	COG0765	amino acid transport
AXW83_RS13045	COG0698	ribose 5-phosphate isomerase
AXW83_RS13050	COG5410	chromosome segregation
AXW83_RS13080	COG4608	Belongs to the ABC transporter superfamily
AXW83_RS13085	COG0444	Belongs to the ABC transporter superfamily
AXW83_RS13105	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AXW83_RS13120	COG0583	DNA-binding transcription factor activity
AXW83_RS13125	COG0702	epimerase
AXW83_RS13135	COG1902	pentaerythritol trinitrate reductase activity
AXW83_RS13170	COG0583	DNA-binding transcription factor activity
AXW83_RS13175	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AXW83_RS13195	COG1137	ATPase activity
AXW83_RS13225	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXW83_RS13230	COG1802	Transcriptional regulator
AXW83_RS13260	COG2267	carboxylic ester hydrolase activity
AXW83_RS13265	COG3842	ATPase activity
AXW83_RS13275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXW83_RS13285	COG5001	Diguanylate cyclase
AXW83_RS13285	COG3300	MHYT domain
AXW83_RS13310	COG0318	PFAM AMP-dependent synthetase and ligase
AXW83_RS13315	COG3181	Tripartite tricarboxylate transporter family receptor
AXW83_RS13320	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXW83_RS13350	COG1129	ABC transporter
AXW83_RS13355	COG4214	carbohydrate transport
AXW83_RS13360	COG1879	ABC-type sugar transport system periplasmic component
AXW83_RS13365	COG0673	inositol 2-dehydrogenase activity
AXW83_RS13380	COG1176	ABC-type spermidine putrescine transport system, permease component I
AXW83_RS13385	COG3833	ABC-type maltose transport systems, permease component
AXW83_RS13390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXW83_RS13395	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
AXW83_RS13400	COG0438	transferase activity, transferring glycosyl groups
AXW83_RS13450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXW83_RS13520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AXW83_RS13525	COG0406	alpha-ribazole phosphatase activity
AXW83_RS13530	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AXW83_RS13535	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AXW83_RS13540	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AXW83_RS13550	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AXW83_RS13560	COG0484	heat shock protein binding
AXW83_RS13570	COG0259	pyridoxamine-phosphate oxidase activity
AXW83_RS13575	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS13580	COG0494	nUDIX hydrolase
AXW83_RS13600	COG0583	DNA-binding transcription factor activity
AXW83_RS13610	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AXW83_RS13615	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AXW83_RS13625	COG2818	Glycosylase
AXW83_RS13630	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AXW83_RS13635	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AXW83_RS13645	COG2852	Protein conserved in bacteria
AXW83_RS13670	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AXW83_RS13680	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS13685	COG1063	alcohol dehydrogenase
AXW83_RS13695	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AXW83_RS13700	COG3920	Histidine kinase
AXW83_RS13700	COG2202	Pas domain
AXW83_RS13705	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AXW83_RS13710	COG0625	glutathione transferase activity
AXW83_RS13715	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AXW83_RS13725	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AXW83_RS13740	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AXW83_RS13745	COG0037	tRNA processing
AXW83_RS13755	COG2885	chlorophyll binding
AXW83_RS13770	COG0848	biopolymer transport protein
AXW83_RS13785	COG1309	transcriptional regulator
AXW83_RS13795	COG0824	Thioesterase
AXW83_RS13805	COG1598	PFAM Uncharacterised protein family UPF0150
AXW83_RS13810	COG2255	four-way junction helicase activity
AXW83_RS13820	COG0632	four-way junction helicase activity
AXW83_RS13825	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AXW83_RS13835	COG0217	transcriptional regulatory protein
AXW83_RS13840	COG1692	metallophosphoesterase
AXW83_RS13885	COG0126	phosphoglycerate kinase activity
AXW83_RS13900	COG3135	benzoate transporter
AXW83_RS13915	COG0483	inositol monophosphate 1-phosphatase activity
AXW83_RS13930	COG2863	cytochrome
AXW83_RS13935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXW83_RS13940	COG1132	(ABC) transporter
AXW83_RS13960	COG0604	alcohol dehydrogenase
AXW83_RS13980	COG0318	PFAM AMP-dependent synthetase and ligase
AXW83_RS14005	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AXW83_RS14010	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AXW83_RS14020	COG1073	alpha beta
AXW83_RS14050	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AXW83_RS14070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AXW83_RS14090	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AXW83_RS14090	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXW83_RS14095	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXW83_RS14120	COG1902	pentaerythritol trinitrate reductase activity
AXW83_RS14125	COG1040	competence protein
AXW83_RS14140	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AXW83_RS14140	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AXW83_RS14185	COG0523	cobalamin synthesis protein
AXW83_RS14190	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AXW83_RS14195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW83_RS14220	COG0494	nUDIX hydrolase
AXW83_RS14225	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AXW83_RS14230	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AXW83_RS14235	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AXW83_RS14240	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AXW83_RS14245	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AXW83_RS14250	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
AXW83_RS14265	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AXW83_RS14275	COG0154	amidase activity
AXW83_RS14290	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AXW83_RS14295	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS14300	COG1917	Cupin 2, conserved barrel domain protein
AXW83_RS14305	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXW83_RS14320	COG0246	Mannitol dehydrogenase
AXW83_RS14330	COG1473	amidohydrolase
AXW83_RS14335	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
AXW83_RS14345	COG2354	Protein conserved in bacteria
AXW83_RS14350	COG0183	Belongs to the thiolase family
AXW83_RS14355	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXW83_RS14355	COG1024	Enoyl-CoA hydratase
AXW83_RS14365	COG1024	Enoyl-CoA hydratase
AXW83_RS14395	COG4953	penicillin-binding protein 1C
AXW83_RS14400	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXW83_RS14410	COG1309	transcriptional regulator
AXW83_RS14415	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AXW83_RS14425	COG3639	organic phosphonate transmembrane transporter activity
AXW83_RS14435	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXW83_RS14450	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AXW83_RS14455	COG3626	phosphonate metabolism
AXW83_RS14460	COG3627	carbon phosphorus lyase activity
AXW83_RS14465	COG4107	phosphonate C-P lyase system protein PhnK
AXW83_RS14470	COG4778	phosphonate C-P lyase system protein PhnL
AXW83_RS14475	COG3454	Phosphonate metabolism
AXW83_RS14520	COG1022	Amp-dependent synthetase and ligase
AXW83_RS14555	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AXW83_RS14560	COG0737	Belongs to the 5'-nucleotidase family
AXW83_RS14565	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AXW83_RS14575	COG3034	peptidoglycan biosynthetic process
AXW83_RS14580	COG0825	malonyl-CoA metabolic process
AXW83_RS14590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXW83_RS14600	COG0456	acetyltransferase
AXW83_RS14605	COG3158	transport of potassium into the cell
AXW83_RS14610	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AXW83_RS14615	COG0735	belongs to the Fur family
AXW83_RS14620	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS14630	COG2264	protein methyltransferase activity
AXW83_RS14655	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXW83_RS14670	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AXW83_RS14675	COG1278	Cold shock
AXW83_RS14680	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AXW83_RS14685	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AXW83_RS14690	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AXW83_RS14695	COG0799	negative regulation of ribosome biogenesis
AXW83_RS14700	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AXW83_RS14710	COG0793	Belongs to the peptidase S41A family
AXW83_RS14720	COG0494	nUDIX hydrolase
AXW83_RS14725	COG0140	phosphoribosyl-ATP diphosphatase activity
AXW83_RS14775	COG2801	Transposase and inactivated derivatives
AXW83_RS14800	COG1126	abc transporter atp-binding protein
AXW83_RS14805	COG0765	amino acid transport
AXW83_RS14815	COG0277	FAD linked oxidase domain protein
AXW83_RS14820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXW83_RS14825	COG1396	sequence-specific DNA binding
AXW83_RS14840	COG1793	dna ligase
AXW83_RS14855	COG0784	Response regulator, receiver
AXW83_RS14855	COG4191	Histidine kinase
AXW83_RS14875	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AXW83_RS14960	COG3842	ATPase activity
AXW83_RS14965	COG3842	ATPase activity
AXW83_RS14975	COG0395	ABC-type sugar transport system, permease component
AXW83_RS15000	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AXW83_RS15005	COG5001	Diguanylate cyclase
AXW83_RS15010	COG1879	ABC-type sugar transport system periplasmic component
AXW83_RS15015	COG1129	ABC transporter
AXW83_RS15020	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXW83_RS15025	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXW83_RS15045	COG3386	PFAM SMP-30 Gluconolaconase
AXW83_RS15060	COG4214	carbohydrate transport
AXW83_RS15065	COG2094	Belongs to the DNA glycosylase MPG family
AXW83_RS15085	COG0512	Glutamine amidotransferase of anthranilate synthase
AXW83_RS15085	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AXW83_RS15090	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AXW83_RS15110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW83_RS15115	COG4597	amino acid ABC transporter
AXW83_RS15120	COG0765	amino acid transport
AXW83_RS15125	COG0583	DNA-binding transcription factor activity
AXW83_RS15155	COG0583	DNA-binding transcription factor activity
AXW83_RS15165	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXW83_RS15200	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AXW83_RS15205	COG4948	Mandelate Racemase Muconate Lactonizing
AXW83_RS15210	COG1802	Transcriptional regulator
AXW83_RS15230	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXW83_RS15240	COG0251	oxidation-reduction process
AXW83_RS15245	COG2188	Transcriptional regulator
AXW83_RS15265	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AXW83_RS15280	COG1960	acyl-CoA dehydrogenase activity
AXW83_RS15290	COG1960	acyl-CoA dehydrogenase activity
AXW83_RS15320	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS15335	COG1024	Enoyl-CoA hydratase
AXW83_RS15340	COG0183	Belongs to the thiolase family
AXW83_RS15345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW83_RS15350	COG0765	amino acid transport
AXW83_RS15355	COG0765	amino acid transport
AXW83_RS15370	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXW83_RS15375	COG4948	Mandelate Racemase Muconate Lactonizing
AXW83_RS15400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXW83_RS15430	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
AXW83_RS15450	COG1476	TRANSCRIPTIONal
AXW83_RS15455	COG4974	Belongs to the 'phage' integrase family
AXW83_RS15460	COG4191	Histidine kinase
AXW83_RS15460	COG0784	Response regulator, receiver
AXW83_RS15465	COG3920	Histidine kinase
AXW83_RS15465	COG2202	Pas domain
AXW83_RS15475	COG2159	amidohydrolase
AXW83_RS15485	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS15490	COG3395	kinase activity
AXW83_RS15495	COG2376	Dihydroxyacetone kinase
AXW83_RS15500	COG2376	Dihydroxyacetone kinase
AXW83_RS15525	COG1414	Transcriptional regulator
AXW83_RS15530	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXW83_RS15535	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXW83_RS15535	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AXW83_RS15540	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXW83_RS15545	COG2182	Extracellular solute-binding protein
AXW83_RS15575	COG0277	FAD linked oxidase domain protein
AXW83_RS15585	COG3833	ABC-type maltose transport systems, permease component
AXW83_RS15595	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS15600	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS15605	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXW83_RS15610	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXW83_RS15615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXW83_RS15630	COG1175	transmembrane transport
AXW83_RS15635	COG0395	ABC-type sugar transport system, permease component
AXW83_RS15655	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS15660	COG0673	inositol 2-dehydrogenase activity
AXW83_RS15675	COG2376	Dihydroxyacetone kinase
AXW83_RS15685	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS15700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW83_RS15730	COG0445	tRNA wobble uridine modification
AXW83_RS15740	COG1175	transmembrane transport
AXW83_RS15745	COG0395	ABC-type sugar transport system, permease component
AXW83_RS15750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXW83_RS15755	COG1609	Transcriptional regulator
AXW83_RS15765	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXW83_RS15780	COG0028	Belongs to the TPP enzyme family
AXW83_RS15790	COG0583	DNA-binding transcription factor activity
AXW83_RS15795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AXW83_RS15800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW83_RS15805	COG0765	amino acid transport
AXW83_RS15810	COG0765	amino acid transport
AXW83_RS15825	COG0583	DNA-binding transcription factor activity
AXW83_RS15830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXW83_RS15840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AXW83_RS15845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW83_RS15875	COG4608	Belongs to the ABC transporter superfamily
AXW83_RS15880	COG0444	Belongs to the ABC transporter superfamily
AXW83_RS15885	COG0601	transmembrane transport
AXW83_RS15890	COG0747	negative chemotaxis
AXW83_RS15945	COG0583	DNA-binding transcription factor activity
AXW83_RS15955	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXW83_RS15975	COG0840	transmembrane signaling receptor activity
AXW83_RS15975	COG3290	protein histidine kinase activity
AXW83_RS15980	COG0668	transmembrane transport
AXW83_RS15995	COG2925	Exonuclease
AXW83_RS16015	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AXW83_RS16070	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AXW83_RS16075	COG1309	transcriptional regulator
AXW83_RS16080	COG0039	L-malate dehydrogenase activity
AXW83_RS16085	COG0045	succinate-CoA ligase (ADP-forming) activity
AXW83_RS16090	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AXW83_RS16095	COG0567	Dehydrogenase, E1 component
AXW83_RS16100	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXW83_RS16120	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AXW83_RS16140	COG1278	Cold shock
AXW83_RS16145	COG0288	reversible hydration of carbon dioxide
AXW83_RS16150	COG1872	DUF167
AXW83_RS16170	COG0784	Response regulator, receiver
AXW83_RS16170	COG4191	Histidine kinase
AXW83_RS16195	COG1126	abc transporter atp-binding protein
AXW83_RS16220	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXW83_RS16245	COG0534	Mate efflux family protein
AXW83_RS16260	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AXW83_RS16275	COG0625	glutathione transferase activity
AXW83_RS16280	COG0142	geranyltranstransferase activity
AXW83_RS16285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AXW83_RS16290	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AXW83_RS16300	COG5001	Diguanylate cyclase
AXW83_RS16310	COG0183	Belongs to the thiolase family
AXW83_RS16325	COG0431	NADPH-dependent FMN reductase
AXW83_RS16345	COG2223	nitrite transmembrane transporter activity
AXW83_RS16360	COG0019	diaminopimelate decarboxylase activity
AXW83_RS16370	COG0165	Argininosuccinate lyase
AXW83_RS16375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXW83_RS16380	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXW83_RS16385	COG1585	Membrane protein implicated in regulation of membrane protease activity
AXW83_RS16390	COG0330	HflC and HflK could
AXW83_RS16395	COG2186	Transcriptional regulator
AXW83_RS16400	COG0287	Prephenate dehydrogenase
AXW83_RS16405	COG0653	protein targeting
AXW83_RS16410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AXW83_RS16425	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AXW83_RS16430	COG2192	nodulation
AXW83_RS16435	COG3813	Protein conserved in bacteria
AXW83_RS16440	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AXW83_RS16455	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AXW83_RS16460	COG0824	Thioesterase
AXW83_RS16470	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AXW83_RS16490	COG2951	lytic endotransglycosylase activity
AXW83_RS16505	COG0070	glutamate synthase
AXW83_RS16505	COG0069	glutamate synthase activity
AXW83_RS16505	COG0067	glutamate synthase
AXW83_RS16520	COG0071	Belongs to the small heat shock protein (HSP20) family
AXW83_RS16525	COG2267	carboxylic ester hydrolase activity
AXW83_RS16530	COG0483	inositol monophosphate 1-phosphatase activity
AXW83_RS16565	COG0789	Transcriptional regulator
AXW83_RS16590	COG4608	Belongs to the ABC transporter superfamily
AXW83_RS16595	COG0444	Belongs to the ABC transporter superfamily
AXW83_RS16600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW83_RS16605	COG0601	transmembrane transport
AXW83_RS16610	COG0747	negative chemotaxis
AXW83_RS16615	COG2217	Heavy metal translocating P-type atpase
AXW83_RS16625	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS16675	COG2986	histidine ammonia-lyase
AXW83_RS16695	COG0747	negative chemotaxis
AXW83_RS16700	COG0601	transmembrane transport
AXW83_RS16705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW83_RS16710	COG0444	Belongs to the ABC transporter superfamily
AXW83_RS16720	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AXW83_RS16725	COG4948	Mandelate Racemase Muconate Lactonizing
AXW83_RS16740	COG1234	tRNA 3'-trailer cleavage
AXW83_RS16745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AXW83_RS16750	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AXW83_RS16760	COG0596	Alpha beta hydrolase
AXW83_RS16775	COG0469	pyruvate kinase activity
AXW83_RS16795	COG3750	Belongs to the UPF0335 family
AXW83_RS16800	COG0598	Magnesium transport protein CorA
AXW83_RS16820	COG2204	response regulator
AXW83_RS16845	COG0494	nUDIX hydrolase
AXW83_RS16855	COG3214	Protein conserved in bacteria
AXW83_RS16875	COG0803	Belongs to the bacterial solute-binding protein 9 family
AXW83_RS16885	COG1121	(ABC) transporter
AXW83_RS16895	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AXW83_RS16910	COG0154	amidase activity
AXW83_RS16940	COG1132	(ABC) transporter
AXW83_RS16950	COG4589	Belongs to the CDS family
AXW83_RS16965	COG0671	phosphoesterase, PA-phosphatase related
AXW83_RS16965	COG2453	phosphatase
AXW83_RS16970	COG2267	carboxylic ester hydrolase activity
AXW83_RS16975	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AXW83_RS17005	COG1012	belongs to the aldehyde dehydrogenase family
AXW83_RS17015	COG0492	ferredoxin-NADP+ reductase activity
AXW83_RS17020	COG1454	alcohol dehydrogenase
AXW83_RS17045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXW83_RS17060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXW83_RS17065	COG4957	zinc ion binding
AXW83_RS17145	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXW83_RS17150	COG0411	ABC transporter
AXW83_RS17195	COG3842	ATPase activity
AXW83_RS17215	COG0683	leucine binding
AXW83_RS17240	COG2267	carboxylic ester hydrolase activity
AXW83_RS17265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXW83_RS17280	COG2309	aminopeptidase activity
AXW83_RS17300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AXW83_RS17320	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AXW83_RS17325	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AXW83_RS17330	COG0181	hydroxymethylbilane synthase activity
AXW83_RS17345	COG0564	pseudouridine synthase activity
AXW83_RS17350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AXW83_RS17385	COG2884	Cell division ATP-binding protein ftsE
AXW83_RS17395	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AXW83_RS17400	COG0745	RESPONSE REGULATOR receiver
AXW83_RS17405	COG1914	H( )-stimulated, divalent metal cation uptake system
AXW83_RS17410	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AXW83_RS17420	COG3179	chitinase
AXW83_RS17430	COG1522	sequence-specific DNA binding
AXW83_RS17450	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AXW83_RS17460	COG0842	Transport permease protein
AXW83_RS17465	COG1131	(ABC) transporter
AXW83_RS17480	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AXW83_RS17490	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AXW83_RS17495	COG5322	oxidoreductase activity
AXW83_RS17495	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AXW83_RS17510	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AXW83_RS17510	COG0546	phosphoglycolate phosphatase activity
AXW83_RS17550	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AXW83_RS17555	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AXW83_RS17575	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AXW83_RS17630	COG1132	(ABC) transporter
AXW83_RS17650	COG0601	transmembrane transport
AXW83_RS17655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW83_RS17660	COG0438	transferase activity, transferring glycosyl groups
AXW83_RS17675	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AXW83_RS17680	COG1177	transmembrane transport
AXW83_RS17685	COG3842	ATPase activity
AXW83_RS17695	COG1176	ABC-type spermidine putrescine transport system, permease component I
AXW83_RS17720	COG2086	electron transfer activity
AXW83_RS17725	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AXW83_RS17730	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXW83_RS17740	COG1473	amidohydrolase
AXW83_RS17745	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AXW83_RS17765	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AXW83_RS17770	COG1609	Transcriptional regulator
AXW83_RS17775	COG2084	Dehydrogenase
AXW83_RS17780	COG3833	ABC-type maltose transport systems, permease component
AXW83_RS17795	COG3842	ATPase activity
AXW83_RS17800	COG2186	Transcriptional regulator
AXW83_RS17805	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AXW83_RS17815	COG1301	dicarboxylic acid transport
AXW83_RS17825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXW83_RS17830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXW83_RS17835	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS17855	COG0129	dihydroxy-acid dehydratase activity
AXW83_RS17875	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AXW83_RS17880	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AXW83_RS17880	COG3743	rRNA binding
AXW83_RS17920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW83_RS17925	COG0601	transmembrane transport
AXW83_RS17930	COG0747	negative chemotaxis
AXW83_RS17935	COG2072	flavoprotein involved in K transport
AXW83_RS17940	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS17975	COG4974	Belongs to the 'phage' integrase family
AXW83_RS17985	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AXW83_RS17990	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AXW83_RS18000	COG4106	trans-aconitate 2-methyltransferase activity
AXW83_RS18005	COG2202	Pas domain
AXW83_RS18005	COG3920	Histidine kinase
AXW83_RS18010	COG4191	Histidine kinase
AXW83_RS18010	COG0784	Response regulator, receiver
AXW83_RS18015	COG1737	Transcriptional regulator
AXW83_RS18030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW83_RS18035	COG0747	negative chemotaxis
AXW83_RS18075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXW83_RS18090	COG0010	Belongs to the arginase family
AXW83_RS18100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXW83_RS18105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXW83_RS18115	COG3842	ATPase activity
AXW83_RS18120	COG1176	ABC-type spermidine putrescine transport system, permease component I
AXW83_RS18130	COG1414	Transcriptional regulator
AXW83_RS18135	COG0625	glutathione transferase activity
AXW83_RS18155	COG2200	EAL domain
AXW83_RS18160	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS18165	COG1309	transcriptional regulator
AXW83_RS18170	COG0582	viral genome integration into host DNA
AXW83_RS18325	COG3118	belongs to the thioredoxin family
AXW83_RS18340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXW83_RS18345	COG0519	Catalyzes the synthesis of GMP from XMP
AXW83_RS18345	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AXW83_RS18350	COG1309	transcriptional regulator
AXW83_RS18365	COG0667	Aldo Keto reductase
AXW83_RS18370	COG1309	transcriptional regulator
AXW83_RS18385	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AXW83_RS18420	COG0668	transmembrane transport
AXW83_RS18435	COG0840	transmembrane signaling receptor activity
AXW83_RS18445	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AXW83_RS18460	COG1595	DNA-templated transcription, initiation
AXW83_RS18485	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AXW83_RS18490	COG2080	2 iron, 2 sulfur cluster binding
AXW83_RS18495	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AXW83_RS18500	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AXW83_RS18525	COG0438	transferase activity, transferring glycosyl groups
AXW83_RS18555	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AXW83_RS18565	COG0138	bifunctional purine biosynthesis protein purh
AXW83_RS18580	COG0501	Belongs to the peptidase M48B family
AXW83_RS18600	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AXW83_RS18610	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AXW83_RS18615	COG1376	ErfK ybiS ycfS ynhG family protein
AXW83_RS18620	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AXW83_RS18625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXW83_RS18630	COG4558	Periplasmic binding protein
AXW83_RS18660	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AXW83_RS18670	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AXW83_RS18680	COG2030	dehydratase
AXW83_RS18690	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AXW83_RS18710	COG5310	Homospermidine synthase
AXW83_RS18715	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AXW83_RS18720	COG1653	transport
AXW83_RS18730	COG1175	transmembrane transport
AXW83_RS18760	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AXW83_RS18785	COG0387	Pfam Sodium calcium exchanger
AXW83_RS18800	COG1132	(ABC) transporter
AXW83_RS18805	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AXW83_RS18815	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AXW83_RS18820	COG3657	addiction module killer protein
AXW83_RS18830	COG3264	Mechanosensitive ion channel
AXW83_RS18830	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AXW83_RS18845	COG1228	amidohydrolase
AXW83_RS18860	COG0735	belongs to the Fur family
AXW83_RS18885	COG0697	spore germination
AXW83_RS18890	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AXW83_RS18905	COG2201	protein-glutamate methylesterase activity
AXW83_RS18950	COG0739	heme binding
AXW83_RS18960	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AXW83_RS18980	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AXW83_RS18990	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AXW83_RS18995	COG0047	phosphoribosylformylglycinamidine synthase activity
AXW83_RS19000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXW83_RS19005	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AXW83_RS19010	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AXW83_RS19015	COG4133	protoheme IX ABC transporter activity
AXW83_RS19020	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AXW83_RS19025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AXW83_RS19030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AXW83_RS19040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AXW83_RS19045	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS19050	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AXW83_RS19060	COG0604	alcohol dehydrogenase
AXW83_RS19060	COG3321	synthase
AXW83_RS19080	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AXW83_RS19085	COG1704	LemA family
AXW83_RS19090	COG0405	Gamma-glutamyltransferase
AXW83_RS19110	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AXW83_RS19140	COG2917	probably involved in intracellular septation
AXW83_RS19145	COG0552	protein localization to endoplasmic reticulum
AXW83_RS19150	COG0564	pseudouridine synthase activity
AXW83_RS19155	COG2154	pterin-4-alpha-carbinolamine dehydratase
AXW83_RS19165	COG0667	Aldo Keto reductase
AXW83_RS19175	COG4181	ATPase activity
AXW83_RS19185	COG0670	Belongs to the BI1 family
AXW83_RS19210	COG2902	Dehydrogenase
AXW83_RS19220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXW83_RS19225	COG1946	Acyl-CoA thioesterase
AXW83_RS19230	COG0347	Belongs to the P(II) protein family
AXW83_RS19235	COG0004	ammonium transporteR
AXW83_RS19260	COG0745	RESPONSE REGULATOR receiver
AXW83_RS19270	COG3706	GGDEF domain
AXW83_RS19275	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AXW83_RS19280	COG0495	leucyl-tRNA aminoacylation
AXW83_RS19305	COG0357	Ribosomal RNA small subunit methyltransferase G
AXW83_RS19310	COG0445	tRNA wobble uridine modification
AXW83_RS19315	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AXW83_RS19320	COG1331	Highly conserved protein containing a thioredoxin domain
AXW83_RS19325	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AXW83_RS19330	COG1981	membrane
AXW83_RS19335	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AXW83_RS19340	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AXW83_RS19345	COG0424	maF-like protein
AXW83_RS19355	COG0237	dephospho-CoA kinase activity
AXW83_RS19360	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AXW83_RS19365	COG1253	flavin adenine dinucleotide binding
AXW83_RS19370	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AXW83_RS19395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXW83_RS19405	COG1185	polyribonucleotide nucleotidyltransferase activity
AXW83_RS19410	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AXW83_RS19415	COG1733	regulation of RNA biosynthetic process
AXW83_RS19430	COG2207	Transcriptional regulator
AXW83_RS19435	COG0840	transmembrane signaling receptor activity
AXW83_RS19440	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AXW83_RS19445	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AXW83_RS19450	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AXW83_RS19465	COG0779	Required for maturation of 30S ribosomal subunits
AXW83_RS19475	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AXW83_RS19480	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AXW83_RS19485	COG1396	sequence-specific DNA binding
AXW83_RS19490	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AXW83_RS19495	COG1253	flavin adenine dinucleotide binding
AXW83_RS19500	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AXW83_RS19505	COG1702	phosphate starvation-inducible protein PhoH
AXW83_RS19510	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AXW83_RS19530	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AXW83_RS19540	COG0180	Tryptophanyl-tRNA synthetase
AXW83_RS19550	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AXW83_RS19555	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AXW83_RS19560	COG0131	Imidazoleglycerol-phosphate dehydratase
AXW83_RS19575	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AXW83_RS19590	COG0107	imidazoleglycerol-phosphate synthase activity
AXW83_RS19595	COG0140	phosphoribosyl-ATP diphosphatase activity
AXW83_RS19600	COG1072	(Pantothenic acid kinase))
AXW83_RS19605	COG1238	metal cluster binding
AXW83_RS19610	COG0251	oxidation-reduction process
AXW83_RS19630	COG2942	2-epimerase
AXW83_RS19635	COG0673	inositol 2-dehydrogenase activity
AXW83_RS19640	COG0673	inositol 2-dehydrogenase activity
AXW83_RS19650	COG4208	sulfate ABC transporter
AXW83_RS19660	COG3842	ATPase activity
AXW83_RS19670	COG1312	Catalyzes the dehydration of D-mannonate
AXW83_RS19680	COG1492	cobalamin metabolic process
AXW83_RS19690	COG1086	Polysaccharide biosynthesis protein
AXW83_RS19700	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AXW83_RS19720	COG2814	Major facilitator Superfamily
AXW83_RS19725	COG1278	Cold shock
AXW83_RS19760	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AXW83_RS19765	COG2011	ABC-type metal ion transport system permease component
AXW83_RS19770	COG1464	Belongs to the NlpA lipoprotein family
AXW83_RS19790	COG3237	CsbD-like
AXW83_RS19795	COG0484	heat shock protein binding
AXW83_RS19800	COG0443	Heat shock 70 kDa protein
AXW83_RS19810	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS19835	COG1402	creatininase
AXW83_RS19840	COG0601	transmembrane transport
AXW83_RS19850	COG4172	Belongs to the ABC transporter superfamily
AXW83_RS19875	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AXW83_RS19880	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AXW83_RS19885	COG0352	thiamine-phosphate diphosphorylase activity
AXW83_RS19890	COG1522	sequence-specific DNA binding
AXW83_RS19900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW83_RS19905	COG1116	anion transmembrane transporter activity
AXW83_RS19915	COG4232	protein-disulfide reductase activity
AXW83_RS19925	COG3842	ATPase activity
AXW83_RS19930	COG0395	ABC-type sugar transport system, permease component
AXW83_RS19945	COG1653	transport
AXW83_RS19975	COG2267	carboxylic ester hydrolase activity
AXW83_RS19985	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AXW83_RS20020	COG1999	signal sequence binding
AXW83_RS20025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXW83_RS20040	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AXW83_RS20075	COG0840	transmembrane signaling receptor activity
AXW83_RS20080	COG2020	methyltransferase activity
AXW83_RS20095	COG2197	response regulator
AXW83_RS20145	COG1476	TRANSCRIPTIONal
AXW83_RS20165	COG2967	ApaG domain
AXW83_RS20175	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AXW83_RS20180	COG0756	dUTP diphosphatase activity
AXW83_RS20185	COG1959	2 iron, 2 sulfur cluster binding
AXW83_RS20200	COG2514	catechol 2,3-dioxygenase activity
AXW83_RS20210	COG1295	ribonuclease BN
AXW83_RS20220	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AXW83_RS20225	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AXW83_RS20230	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AXW83_RS20240	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AXW83_RS20245	COG0594	ribonuclease P activity
AXW83_RS20250	COG0706	membrane insertase activity
AXW83_RS20255	COG0110	maltose O-acetyltransferase activity
AXW83_RS20260	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AXW83_RS20280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AXW83_RS20295	COG3734	2-keto-3-deoxy-galactonokinase
AXW83_RS20300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXW83_RS20305	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AXW83_RS20325	COG4964	Belongs to the GSP D family
AXW83_RS20385	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS20400	COG0156	8-amino-7-oxononanoate synthase activity
AXW83_RS20415	COG0656	L-ascorbic acid biosynthetic process
AXW83_RS20420	COG0285	dihydrofolate synthase activity
AXW83_RS20425	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AXW83_RS20430	COG0159	tryptophan synthase activity
AXW83_RS20455	COG0133	tryptophan synthase activity
AXW83_RS20460	COG0135	phosphoribosylanthranilate isomerase activity
AXW83_RS20480	COG1217	gtp-binding protein TYPA
AXW83_RS20485	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AXW83_RS20490	COG2226	methyltransferase
AXW83_RS20495	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AXW83_RS20505	COG1024	Enoyl-CoA hydratase
AXW83_RS20515	COG0268	Binds directly to 16S ribosomal RNA
AXW83_RS20520	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AXW83_RS20530	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AXW83_RS20540	COG0514	ATP-dependent DNA helicase (RecQ)
AXW83_RS20555	COG2066	Belongs to the glutaminase family
AXW83_RS20560	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AXW83_RS20565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AXW83_RS20570	COG4178	(ABC) transporter
AXW83_RS20590	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AXW83_RS20595	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AXW83_RS20605	COG0765	amino acid transport
AXW83_RS20610	COG4597	amino acid ABC transporter
AXW83_RS20615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW83_RS20620	COG3180	Ammonia monooxygenase
AXW83_RS20635	COG0583	DNA-binding transcription factor activity
AXW83_RS20640	COG2814	Major facilitator Superfamily
AXW83_RS20645	COG0667	Aldo Keto reductase
AXW83_RS20670	COG2814	Major facilitator Superfamily
AXW83_RS20675	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AXW83_RS20695	COG1074	ATP-dependent DNA helicase activity
AXW83_RS20700	COG2887	Belongs to the helicase family. UvrD subfamily
AXW83_RS20705	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AXW83_RS20710	COG3178	'Phosphotransferase
AXW83_RS20715	COG2205	protein histidine kinase activity
AXW83_RS20720	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AXW83_RS20735	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXW83_RS20740	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXW83_RS20750	COG0642	Histidine kinase
AXW83_RS20755	COG0745	RESPONSE REGULATOR receiver
AXW83_RS20765	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AXW83_RS20790	COG1643	Atp-dependent helicase
AXW83_RS20800	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AXW83_RS20805	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AXW83_RS20830	COG3842	ATPase activity
AXW83_RS20845	COG1177	transmembrane transport
AXW83_RS20855	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AXW83_RS20870	COG3609	addiction module antidote protein, CC2985 family
AXW83_RS20880	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AXW83_RS20885	COG0840	transmembrane signaling receptor activity
AXW83_RS20890	COG0281	malic enzyme
AXW83_RS20890	COG0280	phosphate acetyltransferase
AXW83_RS20905	COG0747	negative chemotaxis
AXW83_RS20920	COG0628	permease
AXW83_RS20925	COG0587	DNA-directed DNA polymerase activity
AXW83_RS20940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXW83_RS20945	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
AXW83_RS20950	COG2133	pyrroloquinoline quinone binding
AXW83_RS20960	COG1132	(ABC) transporter
AXW83_RS21025	COG1215	transferase activity, transferring glycosyl groups
AXW83_RS21030	COG1396	sequence-specific DNA binding
AXW83_RS21100	COG1335	isochorismatase
AXW83_RS21120	COG0402	S-adenosylhomocysteine deaminase activity
AXW83_RS21130	COG0765	amino acid transport
AXW83_RS21135	COG0765	amino acid transport
AXW83_RS21140	COG1126	abc transporter atp-binding protein
AXW83_RS21150	COG3608	succinylglutamate desuccinylase aspartoacylase
AXW83_RS21155	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AXW83_RS21175	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AXW83_RS21180	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AXW83_RS21185	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AXW83_RS21200	COG0326	Molecular chaperone. Has ATPase activity
AXW83_RS21205	COG0583	DNA-binding transcription factor activity
AXW83_RS21220	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXW83_RS21225	COG1802	Transcriptional regulator
AXW83_RS21235	COG1175	transmembrane transport
AXW83_RS21240	COG0395	ABC-type sugar transport system, permease component
AXW83_RS21245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXW83_RS21285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW83_RS21290	COG0601	transmembrane transport
AXW83_RS21330	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AXW83_RS21350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW83_RS21355	COG1126	abc transporter atp-binding protein
AXW83_RS21360	COG0765	amino acid transport
AXW83_RS21370	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS21375	COG3684	Belongs to the aldolase LacD family
AXW83_RS21380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXW83_RS21385	COG1414	Transcriptional regulator
AXW83_RS21390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXW83_RS21400	COG0556	nucleotide-excision repair
AXW83_RS21420	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
AXW83_RS21440	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AXW83_RS21455	COG0784	Response regulator, receiver
AXW83_RS21510	COG1596	polysaccharide export
AXW83_RS21525	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AXW83_RS21535	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AXW83_RS21540	COG0460	homoserine dehydrogenase
AXW83_RS21565	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AXW83_RS21565	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AXW83_RS21570	COG0667	Aldo Keto reductase
AXW83_RS21575	COG0745	RESPONSE REGULATOR receiver
AXW83_RS21580	COG0704	Plays a role in the regulation of phosphate uptake
AXW83_RS21585	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AXW83_RS21590	COG0581	inorganic phosphate transmembrane transporter activity
AXW83_RS21600	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AXW83_RS21605	COG5002	protein histidine kinase activity
AXW83_RS21610	COG2326	polyphosphate kinase activity
AXW83_RS21615	COG0392	lysyltransferase activity
AXW83_RS21650	COG1175	transmembrane transport
AXW83_RS21655	COG0395	ABC-type sugar transport system, permease component
AXW83_RS21670	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXW83_RS21680	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXW83_RS21690	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AXW83_RS21710	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AXW83_RS21730	COG0606	chelatase, subunit chli
AXW83_RS21735	COG2862	Uncharacterized protein family, UPF0114
AXW83_RS21740	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXW83_RS21780	COG5001	Diguanylate cyclase
AXW83_RS21780	COG4251	negative regulation of phosphorylation
AXW83_RS21780	COG3706	GGDEF domain
AXW83_RS21780	COG2203	Gaf domain
AXW83_RS21840	COG0596	Alpha beta hydrolase
AXW83_RS21850	COG0745	RESPONSE REGULATOR receiver
AXW83_RS21855	COG2205	protein histidine kinase activity
AXW83_RS21860	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AXW83_RS21865	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AXW83_RS21870	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AXW83_RS21875	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS21880	COG4948	Mandelate Racemase Muconate Lactonizing
AXW83_RS21890	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AXW83_RS21895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW83_RS21905	COG0765	amino acid transport
AXW83_RS21920	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS21925	COG1802	Transcriptional regulator
AXW83_RS21940	COG1129	ABC transporter
AXW83_RS21945	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXW83_RS21950	COG3246	L-lysine catabolic process to acetate
AXW83_RS21980	COG4214	carbohydrate transport
AXW83_RS21995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW83_RS22020	COG2171	N-acyltransferase activity
AXW83_RS22030	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AXW83_RS22035	COG0778	Nitroreductase
AXW83_RS22040	COG1797	cobyrinic acid a,c-diamide synthase activity
AXW83_RS22045	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
AXW83_RS22050	COG2875	Belongs to the precorrin methyltransferase family
AXW83_RS22065	COG2099	Precorrin-6x reductase
AXW83_RS22175	COG1360	Flagellar Motor Protein
AXW83_RS22200	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AXW83_RS22205	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AXW83_RS22210	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AXW83_RS22225	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AXW83_RS22235	COG4786	Flagellar basal body rod
AXW83_RS22240	COG1157	protein secretion by the type III secretion system
AXW83_RS22265	COG1684	flagellar biosynthetic protein fliR
AXW83_RS22270	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AXW83_RS22280	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AXW83_RS22285	COG5443	negative regulation of bacterial-type flagellum assembly
AXW83_RS22305	COG1749	Flagellar hook protein flgE
AXW83_RS22315	COG1815	bacterial-type flagellum-dependent cell motility
AXW83_RS22320	COG1558	bacterial-type flagellum-dependent cell motility
AXW83_RS22325	COG1677	Flagellar hook-basal body complex protein FliE
AXW83_RS22330	COG4786	Flagellar basal body rod
AXW83_RS22340	COG1706	bacterial-type flagellum-dependent cell motility
AXW83_RS22350	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AXW83_RS22360	COG1338	Plays a role in the flagellum-specific transport system
AXW83_RS22370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXW83_RS22390	COG4303	Ethanolamine ammonia lyase large subunit
AXW83_RS22395	COG4302	ethanolamine ammonia-lyase activity
AXW83_RS22420	COG5410	chromosome segregation
AXW83_RS22470	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AXW83_RS22475	COG1215	transferase activity, transferring glycosyl groups
AXW83_RS22480	COG0438	transferase activity, transferring glycosyl groups
AXW83_RS22495	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AXW83_RS22500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXW83_RS22515	COG1215	transferase activity, transferring glycosyl groups
AXW83_RS22550	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AXW83_RS22625	COG4964	Belongs to the GSP D family
AXW83_RS22660	COG2801	Transposase and inactivated derivatives
AXW83_RS22680	COG0438	transferase activity, transferring glycosyl groups
AXW83_RS22680	COG1216	Glycosyl transferase, family 2
AXW83_RS22685	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AXW83_RS22690	COG1091	dTDP-4-dehydrorhamnose reductase activity
AXW83_RS22695	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AXW83_RS22730	COG1309	transcriptional regulator
AXW83_RS22750	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXW83_RS22770	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AXW83_RS22785	COG1177	transmembrane transport
AXW83_RS22790	COG1176	ABC-type spermidine putrescine transport system, permease component I
AXW83_RS22795	COG3842	ATPase activity
AXW83_RS22800	COG2182	Extracellular solute-binding protein
AXW83_RS22805	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AXW83_RS22820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXW83_RS22835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW83_RS22840	COG0601	transmembrane transport
AXW83_RS22845	COG0747	negative chemotaxis
AXW83_RS22860	COG1473	amidohydrolase
AXW83_RS22875	COG0601	transmembrane transport
AXW83_RS22880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW83_RS22885	COG4172	Belongs to the ABC transporter superfamily
AXW83_RS22890	COG0405	Gamma-glutamyltransferase
AXW83_RS22915	COG1278	Cold shock
AXW83_RS22970	COG0789	Transcriptional regulator
AXW83_RS22980	COG1063	alcohol dehydrogenase
AXW83_RS22985	COG1802	Transcriptional regulator
AXW83_RS22990	COG4948	Mandelate Racemase Muconate Lactonizing
AXW83_RS22995	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AXW83_RS23000	COG2894	cell division
AXW83_RS23005	COG0850	regulation of cytokinetic process
AXW83_RS23020	COG3546	catalase activity
AXW83_RS23040	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS23055	COG1376	ErfK ybiS ycfS ynhG family protein
AXW83_RS23055	COG1388	LysM domain
AXW83_RS23065	COG1012	belongs to the aldehyde dehydrogenase family
AXW83_RS23070	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS23075	COG0488	(ABC) transporter
AXW83_RS23085	COG1137	ATPase activity
AXW83_RS23095	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXW83_RS23115	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AXW83_RS23145	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AXW83_RS23145	COG4797	methyltransferase
AXW83_RS23160	COG2815	serine threonine protein kinase
AXW83_RS23160	COG0515	serine threonine protein kinase
AXW83_RS23275	COG0515	serine threonine protein kinase
AXW83_RS23275	COG2815	serine threonine protein kinase
AXW83_RS23340	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AXW83_RS23360	COG3258	Cytochrome c
AXW83_RS23370	COG0446	pyridine nucleotide-disulphide oxidoreductase
AXW83_RS23380	COG1126	abc transporter atp-binding protein
AXW83_RS23405	COG0154	amidase activity
AXW83_RS23430	COG0154	amidase activity
AXW83_RS23440	COG1335	isochorismatase
AXW83_RS23445	COG0747	negative chemotaxis
AXW83_RS23450	COG0601	transmembrane transport
AXW83_RS23455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW83_RS23460	COG4608	Belongs to the ABC transporter superfamily
AXW83_RS23470	COG1335	isochorismatase
AXW83_RS23475	COG0252	asparaginase activity
AXW83_RS23485	COG3180	Ammonia monooxygenase
AXW83_RS23495	COG0154	amidase activity
AXW83_RS23505	COG0697	spore germination
AXW83_RS23510	COG0154	amidase activity
AXW83_RS23520	COG0154	amidase activity
AXW83_RS23530	COG0154	amidase activity
AXW83_RS23550	COG1595	DNA-templated transcription, initiation
AXW83_RS23565	COG4948	Mandelate Racemase Muconate Lactonizing
AXW83_RS23580	COG3842	ATPase activity
AXW83_RS23590	COG1177	transmembrane transport
AXW83_RS23610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXW83_RS23630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXW83_RS23635	COG1802	Transcriptional regulator
AXW83_RS23645	COG0601	transmembrane transport
AXW83_RS23650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW83_RS23660	COG0402	S-adenosylhomocysteine deaminase activity
AXW83_RS23665	COG0444	Belongs to the ABC transporter superfamily
AXW83_RS23690	COG1733	regulation of RNA biosynthetic process
AXW83_RS23700	COG0583	DNA-binding transcription factor activity
AXW83_RS23715	COG0601	transmembrane transport
AXW83_RS23720	COG0444	Belongs to the ABC transporter superfamily
AXW83_RS23725	COG4608	Belongs to the ABC transporter superfamily
AXW83_RS23730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXW83_RS23735	COG3608	succinylglutamate desuccinylase aspartoacylase
AXW83_RS23760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXW83_RS23775	COG1175	transmembrane transport
AXW83_RS23780	COG0395	ABC-type sugar transport system, permease component
AXW83_RS23875	COG1957	nucleoside hydrolase
AXW83_RS23890	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXW83_RS23905	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AXW83_RS23910	COG2188	Transcriptional regulator
AXW83_RS23925	COG4948	Mandelate Racemase Muconate Lactonizing
AXW83_RS23930	COG0765	amino acid transport
AXW83_RS23935	COG0765	amino acid transport
AXW83_RS23940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW83_RS23945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXW83_RS24010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW83_RS24020	COG0747	negative chemotaxis
AXW83_RS24025	COG0583	DNA-binding transcription factor activity
AXW83_RS24035	COG0601	transmembrane transport
AXW83_RS24040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW83_RS24045	COG0444	Belongs to the ABC transporter superfamily
AXW83_RS24050	COG4608	Belongs to the ABC transporter superfamily
AXW83_RS24065	COG2267	carboxylic ester hydrolase activity
AXW83_RS24080	COG0411	ABC transporter
AXW83_RS24100	COG1802	Transcriptional regulator
AXW83_RS24105	COG1012	belongs to the aldehyde dehydrogenase family
AXW83_RS24115	COG3485	protocatechuate 3,4-dioxygenase
AXW83_RS24125	COG3246	L-lysine catabolic process to acetate
AXW83_RS24145	COG0402	S-adenosylhomocysteine deaminase activity
AXW83_RS24155	COG2080	2 iron, 2 sulfur cluster binding
AXW83_RS24160	COG2010	Cytochrome c
AXW83_RS24160	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AXW83_RS24165	COG4191	Histidine kinase
AXW83_RS24165	COG0784	Response regulator, receiver
AXW83_RS24170	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AXW83_RS24175	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AXW83_RS24180	COG2080	2 iron, 2 sulfur cluster binding
AXW83_RS24205	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AXW83_RS24210	COG2010	Cytochrome c
AXW83_RS24210	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AXW83_RS24240	COG0535	radical SAM domain protein
AXW83_RS24245	COG0535	radical SAM domain protein
AXW83_RS24250	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AXW83_RS24255	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AXW83_RS24280	COG2202	Pas domain
AXW83_RS24280	COG3920	Histidine kinase
AXW83_RS24310	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AXW83_RS24355	COG2323	membrane
AXW83_RS24370	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AXW83_RS24375	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS24465	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AXW83_RS24590	COG1793	dna ligase
AXW83_RS24640	COG0582	viral genome integration into host DNA
AXW83_RS24650	COG0840	transmembrane signaling receptor activity
AXW83_RS24675	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AXW83_RS24695	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
AXW83_RS24700	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AXW83_RS24715	COG0137	argininosuccinate synthase activity
AXW83_RS24730	COG0501	Belongs to the peptidase M48B family
AXW83_RS24735	COG1704	LemA family
AXW83_RS24745	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AXW83_RS24760	COG0539	negative regulation of cytoplasmic translation
AXW83_RS24765	COG0443	Heat shock 70 kDa protein
AXW83_RS24770	COG0616	signal peptide processing
AXW83_RS24775	COG0776	regulation of translation
AXW83_RS24790	COG3757	hydrolase, family 25
AXW83_RS24800	COG1960	acyl-CoA dehydrogenase activity
AXW83_RS24810	COG5265	(ABC) transporter
AXW83_RS24835	COG0625	glutathione transferase activity
AXW83_RS24840	COG4770	biotin carboxylase activity
AXW83_RS24850	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AXW83_RS24865	COG0154	amidase activity
AXW83_RS24880	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AXW83_RS24895	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AXW83_RS24900	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AXW83_RS24910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW83_RS24940	COG0242	peptide deformylase activity
AXW83_RS24945	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AXW83_RS24950	COG0101	tRNA pseudouridine synthase activity
AXW83_RS24960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AXW83_RS24970	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AXW83_RS24985	COG1137	ATPase activity
AXW83_RS24990	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AXW83_RS24995	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AXW83_RS25000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXW83_RS25005	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AXW83_RS25005	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AXW83_RS25015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXW83_RS25030	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AXW83_RS25045	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AXW83_RS25065	COG0284	orotidine-5'-phosphate decarboxylase activity
AXW83_RS25080	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AXW83_RS25090	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS25095	COG1960	acyl-CoA dehydrogenase activity
AXW83_RS25120	COG1840	ABC-type Fe3 transport system, periplasmic component
AXW83_RS25130	COG1175	transmembrane transport
AXW83_RS25135	COG0395	ABC-type sugar transport system, permease component
AXW83_RS25140	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AXW83_RS25145	COG0028	Belongs to the TPP enzyme family
AXW83_RS25150	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXW83_RS25155	COG1960	acyl-CoA dehydrogenase activity
AXW83_RS25160	COG1012	belongs to the aldehyde dehydrogenase family
AXW83_RS25165	COG0583	DNA-binding transcription factor activity
AXW83_RS25190	COG0583	DNA-binding transcription factor activity
AXW83_RS25195	COG0753	catalase activity
AXW83_RS25205	COG3387	PFAM Glycoside hydrolase 15-related
AXW83_RS25210	COG1877	trehalose-phosphatase activity
AXW83_RS25215	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AXW83_RS25225	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AXW83_RS25235	COG2890	protein-(glutamine-N5) methyltransferase activity
AXW83_RS25255	COG0542	response to heat
AXW83_RS25260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXW83_RS25260	COG2813	Specifically methylates the guanine in position
AXW83_RS25265	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXW83_RS25280	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AXW83_RS25285	COG0287	Prephenate dehydrogenase
AXW83_RS25295	COG0582	viral genome integration into host DNA
AXW83_RS25300	COG0210	DNA helicase
AXW83_RS25365	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXW83_RS25375	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXW83_RS25390	COG1850	ribulose-bisphosphate carboxylase activity
AXW83_RS25400	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXW83_RS25405	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXW83_RS25410	COG1609	Transcriptional regulator
AXW83_RS25415	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AXW83_RS25435	COG0395	ABC-type sugar transport system, permease component
AXW83_RS25440	COG1175	transmembrane transport
AXW83_RS25445	COG4948	Mandelate Racemase Muconate Lactonizing
AXW83_RS25450	COG2186	Transcriptional regulator
AXW83_RS25465	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS25475	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AXW83_RS25480	COG1960	acyl-CoA dehydrogenase activity
AXW83_RS25495	COG4134	Bacterial extracellular solute-binding protein
AXW83_RS25510	COG4135	transport system, permease component
AXW83_RS25515	COG4136	ATPase activity
AXW83_RS25525	COG1940	carbohydrate kinase activity
AXW83_RS25535	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AXW83_RS25545	COG0400	carboxylic ester hydrolase activity
AXW83_RS25550	COG0346	lactoylglutathione lyase activity
AXW83_RS25560	COG0583	DNA-binding transcription factor activity
AXW83_RS25565	COG3718	enzyme involved in inositol metabolism
AXW83_RS25575	COG3962	Belongs to the TPP enzyme family
AXW83_RS25580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXW83_RS25590	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS25595	COG0673	inositol 2-dehydrogenase activity
AXW83_RS25620	COG1116	anion transmembrane transporter activity
AXW83_RS25625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW83_RS25635	COG1028	Short-chain dehydrogenase reductase Sdr
AXW83_RS25640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXW83_RS25645	COG1414	Transcriptional regulator
AXW83_RS25650	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AXW83_RS25655	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AXW83_RS25690	COG0596	Alpha beta hydrolase
AXW83_RS25700	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AXW83_RS25700	COG4651	solute:proton antiporter activity
AXW83_RS25705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXW83_RS25735	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AXW83_RS25800	COG1201	RNA secondary structure unwinding
AXW83_RS25810	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AXW83_RS25820	COG2755	lipolytic protein G-D-S-L family
AXW83_RS25825	COG1793	dna ligase
AXW83_RS25860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXW83_RS25870	COG5001	Diguanylate cyclase
AXW83_RS25870	COG3300	MHYT domain
AXW83_RS25880	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AXW83_RS25890	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AXW83_RS25895	COG5328	Belongs to the UPF0262 family
AXW83_RS25910	COG4172	Belongs to the ABC transporter superfamily
AXW83_RS25925	COG4239	(ABC) transporter, permease
AXW83_RS25930	COG4174	ABC transporter (Permease)
AXW83_RS25935	COG4166	transmembrane transport
AXW83_RS25940	COG3474	cytochrome
AXW83_RS25945	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AXW83_RS25955	COG2816	NAD+ diphosphatase activity
AXW83_RS25965	COG0028	Belongs to the TPP enzyme family
AXW83_RS25975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW83_RS25990	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AXW83_RS26000	COG2986	histidine ammonia-lyase
AXW83_RS26005	COG1228	amidohydrolase
AXW83_RS26010	COG0402	S-adenosylhomocysteine deaminase activity
AXW83_RS26015	COG2188	Transcriptional regulator
AXW83_RS26035	COG1597	lipid kinase activity
AXW83_RS26040	COG0671	phosphoesterase, PA-phosphatase related
AXW83_RS26060	COG1012	belongs to the aldehyde dehydrogenase family
AXW83_RS26070	COG1733	regulation of RNA biosynthetic process
AXW83_RS26080	COG2307	Protein conserved in bacteria
AXW83_RS26080	COG2308	Evidence 4 Homologs of previously reported genes of
AXW83_RS26095	COG0601	transmembrane transport
AXW83_RS26100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW83_RS26110	COG4608	Belongs to the ABC transporter superfamily
AXW83_RS26115	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AXW83_RS26125	COG0800	Aldolase
AXW83_RS26135	COG0579	oxidoreductase
AXW83_RS26140	COG3041	Addiction module toxin RelE StbE family
AXW83_RS26150	COG1473	amidohydrolase
AXW83_RS26175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AXW83_RS26185	COG0601	transmembrane transport
AXW83_RS26190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW83_RS26200	COG4608	Belongs to the ABC transporter superfamily
AXW83_RS26210	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AXW83_RS26210	COG1618	nucleotide phosphatase activity, acting on free nucleotides
AXW83_RS26215	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AXW83_RS26220	COG0746	molybdenum cofactor guanylyltransferase activity
AXW83_RS26225	COG0489	protein tyrosine kinase activity
AXW83_RS26230	COG0425	Belongs to the sulfur carrier protein TusA family