locus-tag	class	description
CFK39_RS00010	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CFK39_RS00015	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CFK39_RS00020	COG0710	3-dehydroquinate dehydratase activity
CFK39_RS00025	COG2860	membrane
CFK39_RS00030	COG0237	dephospho-CoA kinase activity
CFK39_RS00035	COG0556	nucleotide-excision repair
CFK39_RS00045	COG0765	amino acid transport
CFK39_RS00050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFK39_RS00065	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFK39_RS00065	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFK39_RS00080	COG0322	excinuclease ABC activity
CFK39_RS00085	COG1660	Displays ATPase and GTPase activities
CFK39_RS00095	COG1481	regulation of sporulation
CFK39_RS00100	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CFK39_RS00105	COG0126	phosphoglycerate kinase activity
CFK39_RS00110	COG0149	triose-phosphate isomerase activity
CFK39_RS00115	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CFK39_RS00120	COG0363	glucosamine-6-phosphate deaminase activity
CFK39_RS00130	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CFK39_RS00140	COG0109	protoheme IX farnesyltransferase activity
CFK39_RS00165	COG1160	GTP binding
CFK39_RS00195	COG2409	Drug exporters of the RND superfamily
CFK39_RS00200	COG1846	Transcriptional regulator
CFK39_RS00205	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CFK39_RS00210	COG0006	proline dipeptidase activity
CFK39_RS00215	COG1012	belongs to the aldehyde dehydrogenase family
CFK39_RS00240	COG1053	succinate dehydrogenase
CFK39_RS00245	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CFK39_RS00255	COG1140	nitrate reductase beta subunit
CFK39_RS00325	COG0673	inositol 2-dehydrogenase activity
CFK39_RS00355	COG2814	Major facilitator Superfamily
CFK39_RS00370	COG1309	transcriptional regulator
CFK39_RS00375	COG2409	Drug exporters of the RND superfamily
CFK39_RS00385	COG0587	DNA-directed DNA polymerase activity
CFK39_RS00415	COG1063	alcohol dehydrogenase
CFK39_RS00430	COG1119	ATPase activity
CFK39_RS00435	COG0557	exoribonuclease II activity
CFK39_RS00445	COG0297	glycogen (starch) synthase activity
CFK39_RS00455	COG3830	Belongs to the UPF0237 family
CFK39_RS00455	COG0560	Phosphoserine phosphatase
CFK39_RS00485	COG0584	glycerophosphoryl diester phosphodiesterase
CFK39_RS00500	COG1216	Glycosyl transferase, family 2
CFK39_RS00515	COG4581	dead DEAH box helicase
CFK39_RS00520	COG1597	lipid kinase activity
CFK39_RS00525	COG0805	protein transport
CFK39_RS00530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CFK39_RS00550	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CFK39_RS00555	COG0140	phosphoribosyl-ATP diphosphatase activity
CFK39_RS00565	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CFK39_RS00575	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CFK39_RS00580	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CFK39_RS00595	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CFK39_RS00610	COG1222	aaa ATPase
CFK39_RS00635	COG1968	undecaprenyl-diphosphatase activity
CFK39_RS00660	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CFK39_RS00680	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFK39_RS00685	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CFK39_RS00690	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CFK39_RS00695	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CFK39_RS00700	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CFK39_RS00730	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CFK39_RS00735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFK39_RS00740	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFK39_RS00750	COG0321	lipoyl(octanoyl) transferase activity
CFK39_RS00755	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CFK39_RS00770	COG0174	glutamine synthetase
CFK39_RS00775	COG0402	S-adenosylhomocysteine deaminase activity
CFK39_RS00790	COG3559	Exporter of polyketide antibiotics
CFK39_RS00795	COG1131	(ABC) transporter
CFK39_RS00800	COG1309	transcriptional regulator
CFK39_RS00810	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CFK39_RS00825	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CFK39_RS00850	COG3022	response to hydroperoxide
CFK39_RS00855	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CFK39_RS00860	COG0822	iron-sulfur transferase activity
CFK39_RS00885	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CFK39_RS00895	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFK39_RS00900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFK39_RS00955	COG0358	DNA primase activity
CFK39_RS00960	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CFK39_RS00975	COG0423	glycine-tRNA ligase activity
CFK39_RS00985	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CFK39_RS00990	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFK39_RS01005	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CFK39_RS01010	COG1381	Involved in DNA repair and RecF pathway recombination
CFK39_RS01040	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFK39_RS01065	COG0537	adenosine 5'-monophosphoramidase activity
CFK39_RS01085	COG1420	regulation of RNA biosynthetic process
CFK39_RS01105	COG2258	MOSC domain
CFK39_RS01110	COG0481	GTPase activity
CFK39_RS01130	COG0268	Binds directly to 16S ribosomal RNA
CFK39_RS01145	COG1555	photosystem II stabilization
CFK39_RS01155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFK39_RS01160	COG0318	PFAM AMP-dependent synthetase and ligase
CFK39_RS01165	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFK39_RS01170	COG1082	Xylose isomerase domain protein TIM barrel
CFK39_RS01180	COG1435	thymidine kinase activity
CFK39_RS01195	COG3594	Acyltransferase
CFK39_RS01205	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFK39_RS01215	COG0477	Major facilitator Superfamily
CFK39_RS01220	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CFK39_RS01225	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CFK39_RS01230	COG2873	o-acetylhomoserine
CFK39_RS01235	COG2818	Glycosylase
CFK39_RS01250	COG3104	oligopeptide transport
CFK39_RS01265	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CFK39_RS01275	COG1120	ATPase activity
CFK39_RS01300	COG4868	Belongs to the UPF0371 family
CFK39_RS01340	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CFK39_RS01395	COG0514	ATP-dependent DNA helicase (RecQ)
CFK39_RS01405	COG0494	nUDIX hydrolase
CFK39_RS01410	COG4172	Belongs to the ABC transporter superfamily
CFK39_RS01415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFK39_RS01435	COG3135	benzoate transporter
CFK39_RS01515	COG0799	negative regulation of ribosome biogenesis
CFK39_RS01525	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CFK39_RS01540	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CFK39_RS01545	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CFK39_RS01550	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CFK39_RS01555	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CFK39_RS01560	COG1530	ribonuclease E activity
CFK39_RS01565	COG1271	oxidase subunit
CFK39_RS01570	COG1294	oxidase, subunit
CFK39_RS01580	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CFK39_RS01595	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CFK39_RS01600	COG0571	ribonuclease III activity
CFK39_RS01610	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CFK39_RS01625	COG1403	HNH endonuclease
CFK39_RS01630	COG0742	ribosomal rna small subunit methyltransferase
CFK39_RS01640	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CFK39_RS01645	COG3340	Belongs to the peptidase S51 family
CFK39_RS01650	COG0456	acetyltransferase
CFK39_RS01650	COG0454	-acetyltransferase
CFK39_RS01655	COG1064	alcohol dehydrogenase
CFK39_RS01670	COG1181	Belongs to the D-alanine--D-alanine ligase family
CFK39_RS01690	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CFK39_RS01695	COG0066	3-isopropylmalate dehydratase activity
CFK39_RS01700	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CFK39_RS01705	COG1414	Transcriptional regulator
CFK39_RS01730	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFK39_RS01735	COG0179	Fumarylacetoacetate (FAA) hydrolase
CFK39_RS01775	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CFK39_RS01780	COG1140	nitrate reductase beta subunit
CFK39_RS01805	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CFK39_RS01810	COG0473	3-isopropylmalate dehydrogenase activity
CFK39_RS01820	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CFK39_RS01825	COG0440	acetolactate synthase activity
CFK39_RS01835	COG0129	dihydroxy-acid dehydratase activity
CFK39_RS01845	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFK39_RS01850	COG0154	amidase activity
CFK39_RS01855	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFK39_RS01875	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CFK39_RS01885	COG0482	sulfurtransferase activity
CFK39_RS01925	COG0714	Associated with various cellular activities
CFK39_RS01930	COG1523	belongs to the glycosyl hydrolase 13 family
CFK39_RS01935	COG0366	Alpha amylase catalytic
CFK39_RS01940	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CFK39_RS01960	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CFK39_RS01965	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CFK39_RS01975	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CFK39_RS01980	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CFK39_RS01985	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CFK39_RS01990	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CFK39_RS01995	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CFK39_RS02000	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CFK39_RS02005	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CFK39_RS02010	COG0356	it plays a direct role in the translocation of protons across the membrane
CFK39_RS02020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CFK39_RS02040	COG0254	rRNA binding
CFK39_RS02060	COG0083	homoserine kinase activity
CFK39_RS02065	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CFK39_RS02070	COG0460	homoserine dehydrogenase
CFK39_RS02090	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CFK39_RS02095	COG1196	nuclear chromosome segregation
CFK39_RS02095	COG0739	heme binding
CFK39_RS02095	COG0741	lytic transglycosylase activity
CFK39_RS02105	COG2205	protein histidine kinase activity
CFK39_RS02125	COG1595	DNA-templated transcription, initiation
CFK39_RS02135	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CFK39_RS02140	COG1162	GTPase activity
CFK39_RS02145	COG0483	inositol monophosphate 1-phosphatase activity
CFK39_RS02175	COG1615	UPF0182 protein
CFK39_RS02185	COG0629	single-stranded DNA binding
CFK39_RS02190	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CFK39_RS02200	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CFK39_RS02250	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFK39_RS02260	COG2357	RelA SpoT domain protein
CFK39_RS02265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFK39_RS02290	COG1937	Protein conserved in bacteria
CFK39_RS02300	COG1028	Short-chain dehydrogenase reductase Sdr
CFK39_RS02340	COG0277	FAD linked oxidase domain protein
CFK39_RS02340	COG0247	lactate metabolic process
CFK39_RS02365	COG2226	methyltransferase
CFK39_RS02375	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFK39_RS02385	COG3012	SEC-C Motif Domain Protein
CFK39_RS02395	COG1028	Short-chain dehydrogenase reductase Sdr
CFK39_RS02420	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CFK39_RS02425	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CFK39_RS02430	COG1234	tRNA 3'-trailer cleavage
CFK39_RS02435	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CFK39_RS02445	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CFK39_RS02480	COG1643	Atp-dependent helicase
CFK39_RS02500	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CFK39_RS02505	COG0741	lytic transglycosylase activity
CFK39_RS02505	COG0739	heme binding
CFK39_RS02505	COG1196	nuclear chromosome segregation
CFK39_RS02510	COG2177	Part of the ABC transporter FtsEX involved in
CFK39_RS02515	COG2884	Cell division ATP-binding protein ftsE
CFK39_RS02520	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CFK39_RS02580	COG2197	response regulator
CFK39_RS02585	COG1136	(ABC) transporter
CFK39_RS02585	COG0577	efflux transmembrane transporter activity
CFK39_RS02590	COG4591	ABC-type transport system involved in lipoprotein release permease component
CFK39_RS02650	COG0653	protein targeting
CFK39_RS02655	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CFK39_RS02665	COG5401	PFAM Sporulation and spore germination
CFK39_RS02670	COG5002	protein histidine kinase activity
CFK39_RS02675	COG0745	RESPONSE REGULATOR receiver
CFK39_RS02725	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFK39_RS02745	COG4981	capsule polysaccharide biosynthetic process
CFK39_RS02755	COG0778	Nitroreductase
CFK39_RS02755	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CFK39_RS02775	COG1216	Glycosyl transferase, family 2
CFK39_RS02805	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CFK39_RS02840	COG0438	transferase activity, transferring glycosyl groups
CFK39_RS02860	COG1132	(ABC) transporter
CFK39_RS02870	COG0673	inositol 2-dehydrogenase activity
CFK39_RS02875	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CFK39_RS02880	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CFK39_RS02895	COG2205	protein histidine kinase activity
CFK39_RS02900	COG0745	RESPONSE REGULATOR receiver
CFK39_RS02915	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CFK39_RS02930	COG0424	maF-like protein
CFK39_RS02935	COG4770	biotin carboxylase activity
CFK39_RS02950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFK39_RS02955	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CFK39_RS02970	COG2186	Transcriptional regulator
CFK39_RS02980	COG0494	nUDIX hydrolase
CFK39_RS03015	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CFK39_RS03015	COG1473	amidohydrolase
CFK39_RS03020	COG0662	Cupin 2, conserved barrel domain protein
CFK39_RS03020	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CFK39_RS03025	COG2009	succinate dehydrogenase
CFK39_RS03040	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CFK39_RS03055	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CFK39_RS03060	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CFK39_RS03065	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CFK39_RS03075	COG2030	dehydratase
CFK39_RS03080	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CFK39_RS03100	COG1666	GTP binding
CFK39_RS03135	COG1674	ftsk spoiiie
CFK39_RS03175	COG0714	Associated with various cellular activities
CFK39_RS03205	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CFK39_RS03210	COG0165	Argininosuccinate lyase
CFK39_RS03215	COG0137	argininosuccinate synthase activity
CFK39_RS03220	COG1438	arginine binding
CFK39_RS03225	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CFK39_RS03240	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CFK39_RS03245	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CFK39_RS03250	COG0601	transmembrane transport
CFK39_RS03255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFK39_RS03270	COG4166	transmembrane transport
CFK39_RS03285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFK39_RS03285	COG0072	phenylalanine-tRNA ligase activity
CFK39_RS03290	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CFK39_RS03310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFK39_RS03315	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CFK39_RS03320	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CFK39_RS03325	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CFK39_RS03345	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CFK39_RS03365	COG0131	Imidazoleglycerol-phosphate dehydratase
CFK39_RS03395	COG0395	ABC-type sugar transport system, permease component
CFK39_RS03415	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CFK39_RS03445	COG3189	MarR family transcriptional regulator
CFK39_RS03455	COG2326	polyphosphate kinase activity
CFK39_RS03470	COG1254	Belongs to the acylphosphatase family
CFK39_RS03485	COG2354	Protein conserved in bacteria
CFK39_RS03495	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CFK39_RS03500	COG1349	DNA-binding transcription factor activity
CFK39_RS03510	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CFK39_RS03510	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFK39_RS03510	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFK39_RS03515	COG5522	Integral membrane protein (intg_mem_TP0381)
CFK39_RS03530	COG1435	thymidine kinase activity
CFK39_RS03535	COG3663	DNA glycosylase
CFK39_RS03575	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CFK39_RS03610	COG2814	Major facilitator Superfamily
CFK39_RS03615	COG2207	Transcriptional regulator
CFK39_RS03615	COG0662	Cupin 2, conserved barrel domain protein
CFK39_RS03630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFK39_RS03635	COG1012	belongs to the aldehyde dehydrogenase family
CFK39_RS03655	COG2837	iron assimilation
CFK39_RS03690	COG2154	pterin-4-alpha-carbinolamine dehydratase
CFK39_RS03695	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CFK39_RS03790	COG4115	mRNA cleavage
CFK39_RS03795	COG2161	toxin-antitoxin pair type II binding
CFK39_RS03805	COG1487	ribonuclease activity
CFK39_RS03835	COG2910	NAD(P)H-binding
CFK39_RS03840	COG1733	regulation of RNA biosynthetic process
CFK39_RS03855	COG1570	exodeoxyribonuclease VII activity
CFK39_RS03860	COG1722	exodeoxyribonuclease VII activity
CFK39_RS03875	COG0114	fumarate hydratase activity
CFK39_RS03890	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CFK39_RS03910	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CFK39_RS03920	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CFK39_RS03945	COG1214	PFAM Peptidase M22, glycoprotease
CFK39_RS03950	COG0802	atpase or kinase
CFK39_RS03955	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CFK39_RS03965	COG0736	holo-[acyl-carrier-protein] synthase activity
CFK39_RS03970	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CFK39_RS03975	COG1072	(Pantothenic acid kinase))
CFK39_RS03985	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CFK39_RS03995	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFK39_RS04010	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CFK39_RS04015	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CFK39_RS04020	COG0101	tRNA pseudouridine synthase activity
CFK39_RS04025	COG0151	Belongs to the GarS family
CFK39_RS04030	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CFK39_RS04035	COG1122	ATPase activity
CFK39_RS04055	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFK39_RS04060	COG0047	phosphoribosylformylglycinamidine synthase activity
CFK39_RS04065	COG2813	Specifically methylates the guanine in position
CFK39_RS04070	COG1741	Belongs to the pirin family
CFK39_RS04075	COG0069	glutamate synthase activity
CFK39_RS04080	COG0028	Belongs to the TPP enzyme family
CFK39_RS04085	COG0789	Transcriptional regulator
CFK39_RS04100	COG1028	Short-chain dehydrogenase reductase Sdr
CFK39_RS04105	COG0183	Belongs to the thiolase family
CFK39_RS04150	COG0203	ribosomal protein L17
CFK39_RS04155	COG0202	RNA polymerase activity
CFK39_RS04160	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CFK39_RS04165	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CFK39_RS04170	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CFK39_RS04175	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CFK39_RS04185	COG0563	adenylate kinase activity
CFK39_RS04190	COG0201	protein transport
CFK39_RS04195	COG0200	Binds to the 23S rRNA
CFK39_RS04200	COG1841	ribosomal large subunit assembly
CFK39_RS04205	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CFK39_RS04210	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CFK39_RS04215	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CFK39_RS04220	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CFK39_RS04225	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CFK39_RS04230	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CFK39_RS04235	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CFK39_RS04240	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CFK39_RS04250	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CFK39_RS04255	COG0255	Belongs to the universal ribosomal protein uL29 family
CFK39_RS04260	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CFK39_RS04265	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CFK39_RS04270	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CFK39_RS04275	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CFK39_RS04280	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CFK39_RS04285	COG0089	rRNA binding
CFK39_RS04290	COG0088	Forms part of the polypeptide exit tunnel
CFK39_RS04295	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CFK39_RS04300	COG0051	transcription antitermination factor activity, RNA binding
CFK39_RS04305	COG0395	ABC-type sugar transport system, permease component
CFK39_RS04310	COG1175	transmembrane transport
CFK39_RS04315	COG1653	transport
CFK39_RS04330	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFK39_RS04335	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CFK39_RS04340	COG0049	tRNA binding
CFK39_RS04345	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CFK39_RS04350	COG3583	domain protein
CFK39_RS04355	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CFK39_RS04360	COG0085	RNA polymerase activity
CFK39_RS04365	COG0222	ribosome binding
CFK39_RS04370	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CFK39_RS04375	COG0081	regulation of translation
CFK39_RS04380	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CFK39_RS04390	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CFK39_RS04400	COG0436	Aminotransferase
CFK39_RS04405	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CFK39_RS04410	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CFK39_RS04430	COG1027	Aspartate ammonia-lyase
CFK39_RS04435	COG2326	polyphosphate kinase activity
CFK39_RS04465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFK39_RS04470	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CFK39_RS04475	COG4948	Mandelate Racemase Muconate Lactonizing
CFK39_RS04485	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CFK39_RS04520	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CFK39_RS04530	COG0785	Cytochrome C biogenesis protein
CFK39_RS04540	COG0406	alpha-ribazole phosphatase activity
CFK39_RS04550	COG2353	YceI-like domain
CFK39_RS04575	COG0123	including yeast histone deacetylase and acetoin utilization protein
CFK39_RS04580	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CFK39_RS04585	COG0569	domain protein
CFK39_RS04590	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CFK39_RS04615	COG2372	response to copper ion
CFK39_RS04630	COG1414	Transcriptional regulator
CFK39_RS04650	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CFK39_RS04665	COG0477	Major facilitator Superfamily
CFK39_RS04705	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFK39_RS04720	COG0604	alcohol dehydrogenase
CFK39_RS04725	COG1506	peptidase
CFK39_RS04725	COG0823	Involved in the tonB-independent uptake of proteins
CFK39_RS04745	COG0412	Dienelactone hydrolase
CFK39_RS04750	COG0517	IMP dehydrogenase activity
CFK39_RS04750	COG4175	Glycine betaine
CFK39_RS04755	COG4176	ABC-type proline glycine betaine transport system permease component
CFK39_RS04765	COG0673	inositol 2-dehydrogenase activity
CFK39_RS04770	COG1940	carbohydrate kinase activity
CFK39_RS04780	COG1175	transmembrane transport
CFK39_RS04785	COG0395	ABC-type sugar transport system, permease component
CFK39_RS04790	COG0366	Alpha amylase catalytic
CFK39_RS04810	COG1070	Carbohydrate kinase
CFK39_RS04815	COG1725	Transcriptional regulator
CFK39_RS04820	COG1131	(ABC) transporter
CFK39_RS04855	COG1122	ATPase activity
CFK39_RS04860	COG0183	Belongs to the thiolase family
CFK39_RS04870	COG1268	BioY protein
CFK39_RS04900	COG1725	Transcriptional regulator
CFK39_RS04930	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CFK39_RS04955	COG1115	amino acid carrier protein
CFK39_RS04960	COG0456	acetyltransferase
CFK39_RS04970	COG1917	Cupin 2, conserved barrel domain protein
CFK39_RS04980	COG1739	Uncharacterized protein family UPF0029
CFK39_RS05005	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFK39_RS05010	COG1780	Probably involved in ribonucleotide reductase function
CFK39_RS05050	COG0300	oxidoreductase activity
CFK39_RS05075	COG4585	Histidine kinase
CFK39_RS05080	COG2197	response regulator
CFK39_RS05110	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CFK39_RS05120	COG2212	antiporter activity
CFK39_RS05155	COG0717	Belongs to the dCTP deaminase family
CFK39_RS05185	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFK39_RS05190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFK39_RS05200	COG0488	(ABC) transporter
CFK39_RS05205	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CFK39_RS05225	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CFK39_RS05230	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CFK39_RS05240	COG0022	dehydrogenase e1 component
CFK39_RS05250	COG1737	Transcriptional regulator
CFK39_RS05265	COG0395	ABC-type sugar transport system, permease component
CFK39_RS05270	COG1175	transmembrane transport
CFK39_RS05280	COG0745	RESPONSE REGULATOR receiver
CFK39_RS05300	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CFK39_RS05305	COG1950	PFAM Membrane protein of
CFK39_RS05310	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CFK39_RS05315	COG0300	oxidoreductase activity
CFK39_RS05335	COG1136	(ABC) transporter
CFK39_RS05340	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CFK39_RS05370	COG0456	acetyltransferase
CFK39_RS05390	COG0354	folic acid binding
CFK39_RS05400	COG4129	membrane
CFK39_RS05420	COG0586	Pfam SNARE associated Golgi protein
CFK39_RS05430	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CFK39_RS05435	COG0300	oxidoreductase activity
CFK39_RS05440	COG0708	Exodeoxyribonuclease III
CFK39_RS05475	COG1111	helicase
CFK39_RS05475	COG1205	dead DEAH box helicase
CFK39_RS05480	COG2890	protein-(glutamine-N5) methyltransferase activity
CFK39_RS05490	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CFK39_RS05490	COG1754	DNA topoisomerase type I activity
CFK39_RS05500	COG1175	transmembrane transport
CFK39_RS05505	COG0395	ABC-type sugar transport system, permease component
CFK39_RS05515	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CFK39_RS05520	COG0470	DNA polymerase III
CFK39_RS05530	COG1278	Cold shock
CFK39_RS05540	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CFK39_RS05550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFK39_RS05570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CFK39_RS05575	COG1408	metallophosphoesterase
CFK39_RS05635	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CFK39_RS05640	COG0300	oxidoreductase activity
CFK39_RS05645	COG1134	teichoic acid transport
CFK39_RS05660	COG1215	transferase activity, transferring glycosyl groups
CFK39_RS05675	COG1120	ATPase activity
CFK39_RS05680	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFK39_RS05685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFK39_RS05725	COG1175	transmembrane transport
CFK39_RS05730	COG3833	ABC-type maltose transport systems, permease component
CFK39_RS05755	COG0343	queuine tRNA-ribosyltransferase activity
CFK39_RS05775	COG1362	aminopeptidase activity
CFK39_RS05780	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CFK39_RS05780	COG2755	lipolytic protein G-D-S-L family
CFK39_RS05795	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CFK39_RS05820	COG0181	hydroxymethylbilane synthase activity
CFK39_RS05835	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CFK39_RS05855	COG1832	CoA-binding protein
CFK39_RS05870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFK39_RS05885	COG1285	pathogenesis
CFK39_RS05895	COG0438	transferase activity, transferring glycosyl groups
CFK39_RS05895	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CFK39_RS05915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CFK39_RS05925	COG1716	ATPase activity
CFK39_RS05940	COG0768	penicillin binding
CFK39_RS05945	COG0515	serine threonine protein kinase
CFK39_RS05950	COG0515	serine threonine protein kinase
CFK39_RS05965	COG3764	Sortase (surface protein transpeptidase)
CFK39_RS05990	COG0640	Transcriptional regulator
CFK39_RS06020	COG0277	FAD linked oxidase domain protein
CFK39_RS06030	COG1028	Short-chain dehydrogenase reductase Sdr
CFK39_RS06045	COG1126	abc transporter atp-binding protein
CFK39_RS06050	COG0765	amino acid transport
CFK39_RS06085	COG1132	(ABC) transporter
CFK39_RS06090	COG1132	(ABC) transporter
CFK39_RS06125	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFK39_RS06130	COG0419	ATPase involved in DNA repair
CFK39_RS06135	COG0420	3'-5' exonuclease activity
CFK39_RS06140	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CFK39_RS06140	COG0351	phosphomethylpyrimidine kinase
CFK39_RS06140	COG0352	thiamine-phosphate diphosphorylase activity
CFK39_RS06150	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CFK39_RS06155	COG0352	thiamine-phosphate diphosphorylase activity
CFK39_RS06175	COG3971	2-oxopent-4-enoate hydratase activity
CFK39_RS06185	COG1012	belongs to the aldehyde dehydrogenase family
CFK39_RS06200	COG0477	Major facilitator Superfamily
CFK39_RS06225	COG2226	methyltransferase
CFK39_RS06240	COG1252	NADH dehydrogenase
CFK39_RS06255	COG0714	Associated with various cellular activities
CFK39_RS06305	COG0183	Belongs to the thiolase family
CFK39_RS06310	COG1752	Esterase of the alpha-beta hydrolase superfamily
CFK39_RS06365	COG5002	protein histidine kinase activity
CFK39_RS06370	COG2205	protein histidine kinase activity
CFK39_RS06370	COG2202	Pas domain
CFK39_RS06375	COG0745	RESPONSE REGULATOR receiver
CFK39_RS06380	COG2755	lipolytic protein G-D-S-L family
CFK39_RS06380	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CFK39_RS06445	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CFK39_RS06460	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CFK39_RS06465	COG1388	LysM domain
CFK39_RS06465	COG1134	teichoic acid transport
CFK39_RS06490	COG0395	ABC-type sugar transport system, permease component
CFK39_RS06515	COG0583	DNA-binding transcription factor activity
CFK39_RS06520	COG2855	membrane
CFK39_RS06535	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CFK39_RS06570	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CFK39_RS06575	COG1937	Protein conserved in bacteria
CFK39_RS06580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFK39_RS06595	COG3639	organic phosphonate transmembrane transporter activity
CFK39_RS06605	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CFK39_RS06655	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CFK39_RS06660	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CFK39_RS06670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFK39_RS06675	COG1940	carbohydrate kinase activity
CFK39_RS06680	COG3158	transport of potassium into the cell
CFK39_RS06710	COG4209	transmembrane transport
CFK39_RS06715	COG0395	ABC-type sugar transport system, permease component
CFK39_RS06730	COG1175	transmembrane transport
CFK39_RS06735	COG0395	ABC-type sugar transport system, permease component
CFK39_RS06740	COG1653	transport
CFK39_RS06745	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CFK39_RS06760	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CFK39_RS06790	COG1301	dicarboxylic acid transport
CFK39_RS06800	COG1090	epimerase
CFK39_RS06810	COG1115	amino acid carrier protein
CFK39_RS06815	COG0667	Aldo Keto reductase
CFK39_RS06825	COG1012	belongs to the aldehyde dehydrogenase family
CFK39_RS06860	COG0569	domain protein
CFK39_RS06865	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CFK39_RS06870	COG0798	PFAM Bile acid sodium symporter
CFK39_RS06915	COG0733	neurotransmitter:sodium symporter activity
CFK39_RS06925	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CFK39_RS06955	COG2011	ABC-type metal ion transport system permease component
CFK39_RS06960	COG1464	Belongs to the NlpA lipoprotein family
CFK39_RS06965	COG1506	peptidase
CFK39_RS06965	COG0823	Involved in the tonB-independent uptake of proteins
CFK39_RS06970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFK39_RS06980	COG3408	Glycogen debranching enzyme
CFK39_RS06980	COG3119	arylsulfatase activity
CFK39_RS06990	COG2188	Transcriptional regulator
CFK39_RS07005	COG0395	ABC-type sugar transport system, permease component
CFK39_RS07010	COG3119	arylsulfatase activity
CFK39_RS07015	COG3408	Glycogen debranching enzyme
CFK39_RS07015	COG3119	arylsulfatase activity
CFK39_RS07020	COG3119	arylsulfatase activity
CFK39_RS07030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFK39_RS07035	COG1609	Transcriptional regulator
CFK39_RS07040	COG3547	Transposase (IS116 IS110 IS902 family)
CFK39_RS07055	COG0673	inositol 2-dehydrogenase activity
CFK39_RS07070	COG4948	Mandelate Racemase Muconate Lactonizing
CFK39_RS07105	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CFK39_RS07140	COG0395	ABC-type sugar transport system, permease component
CFK39_RS07145	COG1175	transmembrane transport
CFK39_RS07155	COG4214	carbohydrate transport
CFK39_RS07165	COG4213	ABC transporter substrate-binding protein
CFK39_RS07170	COG1609	Transcriptional regulator
CFK39_RS07185	COG2160	L-arabinose isomerase activity
CFK39_RS07225	COG3425	synthase
CFK39_RS07245	COG1984	allophanate hydrolase subunit 2
CFK39_RS07250	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CFK39_RS07255	COG0477	Major facilitator Superfamily
CFK39_RS07260	COG0698	ribose 5-phosphate isomerase
CFK39_RS07265	COG2376	Dihydroxyacetone kinase
CFK39_RS07275	COG2814	Major facilitator Superfamily
CFK39_RS07280	COG1063	alcohol dehydrogenase
CFK39_RS07310	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CFK39_RS07315	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CFK39_RS07320	COG2390	Transcriptional regulator
CFK39_RS07335	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CFK39_RS07365	COG1174	glycine betaine transport
CFK39_RS07370	COG0517	IMP dehydrogenase activity
CFK39_RS07370	COG1125	glycine betaine transport
CFK39_RS07380	COG0765	amino acid transport
CFK39_RS07390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFK39_RS07395	COG1126	abc transporter atp-binding protein
CFK39_RS07400	COG0351	phosphomethylpyrimidine kinase
CFK39_RS07420	COG1024	Enoyl-CoA hydratase
CFK39_RS07420	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFK39_RS07505	COG0183	Belongs to the thiolase family
CFK39_RS07515	COG3835	regulator
CFK39_RS07540	COG0259	pyridoxamine-phosphate oxidase activity
CFK39_RS07545	COG3757	hydrolase, family 25
CFK39_RS07545	COG3409	Peptidoglycan-binding domain 1 protein
CFK39_RS07560	COG0386	Belongs to the glutathione peroxidase family
CFK39_RS07590	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CFK39_RS07595	COG0589	response to stress
CFK39_RS07600	COG0531	amino acid
CFK39_RS07655	COG1289	transmembrane transporter activity
CFK39_RS07685	COG1028	Short-chain dehydrogenase reductase Sdr
CFK39_RS07700	COG2986	histidine ammonia-lyase
CFK39_RS07710	COG1228	amidohydrolase
CFK39_RS07720	COG0667	Aldo Keto reductase
CFK39_RS07770	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CFK39_RS07775	COG1476	TRANSCRIPTIONal
CFK39_RS07800	COG1528	Iron-storage protein
CFK39_RS07805	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CFK39_RS07810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFK39_RS07830	COG0793	Belongs to the peptidase S41A family
CFK39_RS07830	COG4946	Tricorn protease homolog
CFK39_RS07855	COG2847	Copper chaperone PCu(A)C
CFK39_RS07860	COG2837	iron assimilation
CFK39_RS07875	COG0246	Mannitol dehydrogenase
CFK39_RS07880	COG1904	glucuronate isomerase
CFK39_RS07885	COG1609	Transcriptional regulator
CFK39_RS07890	COG1691	(AIR) carboxylase
CFK39_RS07910	COG0789	Transcriptional regulator
CFK39_RS07915	COG0659	secondary active sulfate transmembrane transporter activity
CFK39_RS07935	COG0667	Aldo Keto reductase
CFK39_RS07945	COG2217	Heavy metal translocating P-type atpase
CFK39_RS07965	COG0302	gtp cyclohydrolase
CFK39_RS07995	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CFK39_RS08010	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CFK39_RS08020	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CFK39_RS08030	COG1253	flavin adenine dinucleotide binding
CFK39_RS08060	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CFK39_RS08065	COG1940	carbohydrate kinase activity
CFK39_RS08075	COG0673	inositol 2-dehydrogenase activity
CFK39_RS08080	COG1063	alcohol dehydrogenase
CFK39_RS08100	COG0598	Magnesium transport protein CorA
CFK39_RS08105	COG2267	carboxylic ester hydrolase activity
CFK39_RS08130	COG0359	binds to the 23S rRNA
CFK39_RS08135	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CFK39_RS08145	COG0360	Binds together with S18 to 16S ribosomal RNA
CFK39_RS08155	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CFK39_RS08170	COG0728	peptidoglycan biosynthetic process
CFK39_RS08200	COG1192	Involved in chromosome partitioning
CFK39_RS08205	COG0357	Ribosomal RNA small subunit methyltransferase G
CFK39_RS08225	COG0594	ribonuclease P activity
CFK39_RS08230	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CFK39_RS08235	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CFK39_RS08240	COG0592	DNA-directed DNA polymerase activity
CFK39_RS08250	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CFK39_RS08265	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFK39_RS08265	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFK39_RS08270	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CFK39_RS08275	COG0187	DNA topoisomerase II activity
CFK39_RS08290	COG0442	prolyl-tRNA aminoacylation
CFK39_RS08310	COG1595	DNA-templated transcription, initiation
CFK39_RS08370	COG4941	Belongs to the sigma-70 factor family
CFK39_RS08375	COG3795	YCII-related domain
CFK39_RS08390	COG0789	Transcriptional regulator
CFK39_RS08395	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CFK39_RS08400	COG2203	Gaf domain
CFK39_RS08400	COG4585	Histidine kinase
CFK39_RS08405	COG2197	response regulator
CFK39_RS08420	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CFK39_RS08425	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CFK39_RS08435	COG0110	maltose O-acetyltransferase activity
CFK39_RS08440	COG0673	inositol 2-dehydrogenase activity
CFK39_RS08450	COG1522	sequence-specific DNA binding
CFK39_RS08460	COG0022	dehydrogenase e1 component
CFK39_RS08465	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFK39_RS08470	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CFK39_RS08490	COG1960	acyl-CoA dehydrogenase activity
CFK39_RS08505	COG0149	triose-phosphate isomerase activity
CFK39_RS08510	COG0698	ribose 5-phosphate isomerase
CFK39_RS08525	COG1028	Short-chain dehydrogenase reductase Sdr
CFK39_RS08530	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFK39_RS08535	COG2610	gluconate transmembrane transporter activity
CFK39_RS08545	COG2084	Dehydrogenase
CFK39_RS08555	COG0179	Fumarylacetoacetate (FAA) hydrolase
CFK39_RS08560	COG4948	Mandelate Racemase Muconate Lactonizing
CFK39_RS08580	COG2186	Transcriptional regulator
CFK39_RS08600	COG1470	cell adhesion involved in biofilm formation
CFK39_RS08600	COG0366	Alpha amylase catalytic
CFK39_RS08610	COG1940	carbohydrate kinase activity
CFK39_RS08625	COG0656	L-ascorbic acid biosynthetic process
CFK39_RS08630	COG1486	melibiose metabolic process
CFK39_RS08635	COG1349	DNA-binding transcription factor activity
CFK39_RS08645	COG1175	transmembrane transport
CFK39_RS08650	COG0395	ABC-type sugar transport system, permease component
CFK39_RS08680	COG1780	Probably involved in ribonucleotide reductase function
CFK39_RS08690	COG1121	(ABC) transporter
CFK39_RS08695	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFK39_RS08700	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFK39_RS08700	COG1321	iron dependent repressor
CFK39_RS08790	COG0604	alcohol dehydrogenase
CFK39_RS08805	COG1501	Belongs to the glycosyl hydrolase 31 family
CFK39_RS08840	COG3119	arylsulfatase activity
CFK39_RS08845	COG0406	alpha-ribazole phosphatase activity
CFK39_RS08850	COG2376	Dihydroxyacetone kinase
CFK39_RS08880	COG2318	DinB family
CFK39_RS08900	COG4948	Mandelate Racemase Muconate Lactonizing
CFK39_RS08915	COG2814	Major facilitator Superfamily
CFK39_RS08920	COG1846	Transcriptional regulator
CFK39_RS08935	COG2239	Acts as a magnesium transporter
CFK39_RS08950	COG2985	domain, Protein
CFK39_RS08950	COG0569	domain protein
CFK39_RS08955	COG0673	inositol 2-dehydrogenase activity
CFK39_RS08975	COG1175	transmembrane transport
CFK39_RS08980	COG1653	transport
CFK39_RS09005	COG4209	transmembrane transport
CFK39_RS09010	COG0395	ABC-type sugar transport system, permease component
CFK39_RS09025	COG3458	cephalosporin-C deacetylase activity
CFK39_RS09030	COG1609	Transcriptional regulator
CFK39_RS09080	COG0673	inositol 2-dehydrogenase activity
CFK39_RS09100	COG4989	oxidoreductase activity
CFK39_RS09105	COG2814	Major facilitator Superfamily
CFK39_RS09135	COG1511	domain protein
CFK39_RS09195	COG1132	(ABC) transporter
CFK39_RS09200	COG1132	(ABC) transporter
CFK39_RS09245	COG0583	DNA-binding transcription factor activity
CFK39_RS09260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFK39_RS09265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFK39_RS09275	COG1126	abc transporter atp-binding protein
CFK39_RS09325	COG2197	response regulator
CFK39_RS09360	COG1136	(ABC) transporter
CFK39_RS09360	COG0577	efflux transmembrane transporter activity
CFK39_RS09375	COG1253	flavin adenine dinucleotide binding
CFK39_RS09380	COG0028	Belongs to the TPP enzyme family
CFK39_RS09390	COG1482	cell wall glycoprotein biosynthetic process
CFK39_RS09435	COG1652	LysM domain
CFK39_RS09460	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CFK39_RS09480	COG1063	alcohol dehydrogenase
CFK39_RS09485	COG0156	8-amino-7-oxononanoate synthase activity
CFK39_RS09495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFK39_RS09535	COG0489	protein tyrosine kinase activity
CFK39_RS09545	COG1132	(ABC) transporter
CFK39_RS09565	COG0438	transferase activity, transferring glycosyl groups
CFK39_RS09590	COG5000	phosphorelay sensor kinase activity
CFK39_RS09590	COG5002	protein histidine kinase activity
CFK39_RS09620	COG0076	glutamate decarboxylase activity
CFK39_RS09645	COG0305	Participates in initiation and elongation during chromosome replication
CFK39_RS09650	COG1403	HNH endonuclease
CFK39_RS09665	COG1764	response to oxidative stress
CFK39_RS09680	COG1597	lipid kinase activity
CFK39_RS09720	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CFK39_RS09735	COG0745	RESPONSE REGULATOR receiver
CFK39_RS09745	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CFK39_RS09750	COG0590	tRNA wobble adenosine to inosine editing
CFK39_RS09760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFK39_RS09770	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CFK39_RS09775	COG2011	ABC-type metal ion transport system permease component
CFK39_RS09780	COG1464	Belongs to the NlpA lipoprotein family
CFK39_RS09815	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFK39_RS09830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFK39_RS09850	COG0252	asparaginase activity
CFK39_RS09860	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CFK39_RS09900	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CFK39_RS09910	COG0385	Bile acid
CFK39_RS09950	COG0656	L-ascorbic acid biosynthetic process
CFK39_RS09960	COG0673	inositol 2-dehydrogenase activity
CFK39_RS09970	COG0395	ABC-type sugar transport system, permease component
CFK39_RS09975	COG1175	transmembrane transport
CFK39_RS09980	COG1653	transport
CFK39_RS09985	COG1609	Transcriptional regulator
CFK39_RS10000	COG3842	ATPase activity
CFK39_RS10010	COG0395	ABC-type sugar transport system, permease component
CFK39_RS10015	COG1175	transmembrane transport
CFK39_RS10020	COG3387	PFAM Glycoside hydrolase 15-related
CFK39_RS10045	COG1175	transmembrane transport
CFK39_RS10050	COG0395	ABC-type sugar transport system, permease component
CFK39_RS10070	COG0395	ABC-type sugar transport system, permease component
CFK39_RS10075	COG4209	transmembrane transport
CFK39_RS10080	COG0673	inositol 2-dehydrogenase activity
CFK39_RS10095	COG0254	rRNA binding
CFK39_RS10105	COG0254	rRNA binding
CFK39_RS10145	COG0823	Involved in the tonB-independent uptake of proteins
CFK39_RS10150	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CFK39_RS10160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFK39_RS10175	COG0463	Glycosyl transferase, family 2
CFK39_RS10200	COG1233	COG1233 Phytoene dehydrogenase and related
CFK39_RS10215	COG0702	epimerase
CFK39_RS10225	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CFK39_RS10235	COG2264	protein methyltransferase activity
CFK39_RS10255	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFK39_RS10260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFK39_RS10270	COG3424	synthase
CFK39_RS10280	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CFK39_RS10295	COG1024	Enoyl-CoA hydratase
CFK39_RS10300	COG1028	Short-chain dehydrogenase reductase Sdr
CFK39_RS10305	COG1960	acyl-CoA dehydrogenase activity
CFK39_RS10310	COG1309	transcriptional regulator
CFK39_RS10320	COG2814	Major facilitator Superfamily
CFK39_RS10335	COG1609	Transcriptional regulator
CFK39_RS10345	COG3938	Belongs to the proline racemase family
CFK39_RS10360	COG0395	ABC-type sugar transport system, permease component
CFK39_RS10365	COG4209	transmembrane transport
CFK39_RS10370	COG2182	Extracellular solute-binding protein
CFK39_RS10390	COG0464	growth
CFK39_RS10405	COG2391	methyltransferase activity
CFK39_RS10410	COG0425	Belongs to the sulfur carrier protein TusA family
CFK39_RS10415	COG4166	transmembrane transport
CFK39_RS10440	COG3246	L-lysine catabolic process to acetate
CFK39_RS10445	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFK39_RS10460	COG0300	oxidoreductase activity
CFK39_RS10525	COG1175	transmembrane transport
CFK39_RS10530	COG1653	transport
CFK39_RS10535	COG1609	Transcriptional regulator
CFK39_RS10545	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CFK39_RS10555	COG2723	6-phospho-beta-galactosidase activity
CFK39_RS10590	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CFK39_RS10635	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CFK39_RS10640	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CFK39_RS10645	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CFK39_RS10690	COG1609	Transcriptional regulator
CFK39_RS10695	COG1129	ABC transporter
CFK39_RS10700	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFK39_RS10710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFK39_RS10715	COG1869	D-ribose catabolic process
CFK39_RS10720	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CFK39_RS10740	COG0477	Major facilitator Superfamily
CFK39_RS10750	COG1473	amidohydrolase
CFK39_RS10765	COG0395	ABC-type sugar transport system, permease component
CFK39_RS10770	COG4209	transmembrane transport
CFK39_RS10780	COG1940	carbohydrate kinase activity
CFK39_RS10785	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CFK39_RS10800	COG2807	transmembrane transport
CFK39_RS10810	COG1414	Transcriptional regulator
CFK39_RS10825	COG1024	Enoyl-CoA hydratase
CFK39_RS10830	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFK39_RS10840	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFK39_RS10845	COG4608	Belongs to the ABC transporter superfamily
CFK39_RS10850	COG0444	Belongs to the ABC transporter superfamily
CFK39_RS10855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFK39_RS10860	COG0601	transmembrane transport
CFK39_RS10880	COG0783	Belongs to the Dps family
CFK39_RS10905	COG0277	FAD linked oxidase domain protein
CFK39_RS10935	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CFK39_RS10940	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CFK39_RS10965	COG3119	arylsulfatase activity
CFK39_RS10970	COG2814	Major facilitator Superfamily
CFK39_RS10975	COG2197	response regulator
CFK39_RS10990	COG1609	Transcriptional regulator
CFK39_RS11000	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CFK39_RS11005	COG3876	Protein conserved in bacteria
CFK39_RS11010	COG1472	Belongs to the glycosyl hydrolase 3 family
CFK39_RS11035	COG0667	Aldo Keto reductase
CFK39_RS11050	COG1074	ATP-dependent DNA helicase activity
CFK39_RS11060	COG3119	arylsulfatase activity
CFK39_RS11065	COG0395	ABC-type sugar transport system, permease component
CFK39_RS11070	COG1175	transmembrane transport
CFK39_RS11080	COG1609	Transcriptional regulator
CFK39_RS11090	COG0386	Belongs to the glutathione peroxidase family
CFK39_RS11095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFK39_RS11105	COG1902	pentaerythritol trinitrate reductase activity
CFK39_RS11105	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFK39_RS11110	COG1335	isochorismatase
CFK39_RS11155	COG3642	lipopolysaccharide core region biosynthetic process
CFK39_RS11170	COG2814	Major facilitator Superfamily
CFK39_RS11190	COG0501	Belongs to the peptidase M48B family
CFK39_RS11210	COG1131	(ABC) transporter
CFK39_RS11220	COG4585	Histidine kinase
CFK39_RS11225	COG2197	response regulator
CFK39_RS11235	COG1132	(ABC) transporter
CFK39_RS11275	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CFK39_RS11285	COG0402	S-adenosylhomocysteine deaminase activity
CFK39_RS11290	COG2252	PERMEase
CFK39_RS11310	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFK39_RS11320	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CFK39_RS11325	COG0657	acetylesterase activity
CFK39_RS11335	COG0018	arginyl-trna synthetase
CFK39_RS11370	COG2233	PERMEase
CFK39_RS11380	COG1012	belongs to the aldehyde dehydrogenase family
CFK39_RS11425	COG2066	Belongs to the glutaminase family
CFK39_RS11465	COG0077	Prephenate dehydratase
CFK39_RS11485	COG1597	lipid kinase activity
CFK39_RS11490	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CFK39_RS11495	COG0561	phosphatase activity
CFK39_RS11500	COG0604	alcohol dehydrogenase
CFK39_RS11505	COG0604	alcohol dehydrogenase
CFK39_RS11515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFK39_RS11520	COG1131	(ABC) transporter
CFK39_RS11545	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CFK39_RS11550	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFK39_RS11560	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFK39_RS11560	COG2213	PTS system mannitol-specific
CFK39_RS11580	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CFK39_RS11590	COG1278	Cold shock
CFK39_RS11615	COG1609	Transcriptional regulator
CFK39_RS11625	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CFK39_RS11650	COG0765	amino acid transport
CFK39_RS11660	COG1126	abc transporter atp-binding protein
CFK39_RS11665	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CFK39_RS11685	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CFK39_RS11740	COG1940	carbohydrate kinase activity
CFK39_RS11740	COG1846	Transcriptional regulator
CFK39_RS11750	COG0395	ABC-type sugar transport system, permease component
CFK39_RS11755	COG4209	transmembrane transport
CFK39_RS11790	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFK39_RS11790	COG0515	serine threonine protein kinase
CFK39_RS11815	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CFK39_RS11830	COG0459	protein refolding
CFK39_RS11845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFK39_RS11850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFK39_RS11860	COG0277	FAD linked oxidase domain protein
CFK39_RS11865	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CFK39_RS11870	COG0640	Transcriptional regulator
CFK39_RS11875	COG0318	PFAM AMP-dependent synthetase and ligase
CFK39_RS11895	COG2188	Transcriptional regulator
CFK39_RS11910	COG1120	ATPase activity
CFK39_RS11930	COG0328	RNA-DNA hybrid ribonuclease activity
CFK39_RS11950	COG2205	protein histidine kinase activity
CFK39_RS11955	COG0745	RESPONSE REGULATOR receiver
CFK39_RS11960	COG5416	Lipopolysaccharide assembly protein A domain
CFK39_RS11965	COG1061	Type III restriction enzyme res subunit
CFK39_RS11970	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CFK39_RS11990	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CFK39_RS11995	COG1940	carbohydrate kinase activity
CFK39_RS12000	COG2814	Major facilitator Superfamily
CFK39_RS12005	COG0626	cystathionine gamma-synthase activity
CFK39_RS12015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFK39_RS12030	COG0351	phosphomethylpyrimidine kinase
CFK39_RS12035	COG1472	Belongs to the glycosyl hydrolase 3 family
CFK39_RS12045	COG1505	serine-type exopeptidase activity
CFK39_RS12055	COG0596	Alpha beta hydrolase
CFK39_RS12070	COG1404	Belongs to the peptidase S8 family
CFK39_RS12085	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CFK39_RS12105	COG0444	Belongs to the ABC transporter superfamily
CFK39_RS12115	COG4166	transmembrane transport
CFK39_RS12130	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFK39_RS12135	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CFK39_RS12140	COG1929	Belongs to the glycerate kinase type-1 family
CFK39_RS12145	COG3960	tartronate-semialdehyde synthase activity
CFK39_RS12150	COG2084	Dehydrogenase
CFK39_RS12155	COG3622	Belongs to the hyi family
CFK39_RS12160	COG3257	ureidoglycine aminohydrolase activity
CFK39_RS12180	COG1414	Transcriptional regulator
CFK39_RS12185	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CFK39_RS12190	COG2233	PERMEase
CFK39_RS12230	COG0714	Associated with various cellular activities
CFK39_RS12250	COG0604	alcohol dehydrogenase
CFK39_RS12250	COG1028	Short-chain dehydrogenase reductase Sdr
CFK39_RS12250	COG3321	synthase
CFK39_RS12265	COG0747	negative chemotaxis
CFK39_RS12295	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CFK39_RS12305	COG0315	cyclic pyranopterin monophosphate synthase activity
CFK39_RS12310	COG0521	Mo-molybdopterin cofactor biosynthetic process
CFK39_RS12310	COG0315	cyclic pyranopterin monophosphate synthase activity
CFK39_RS12325	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CFK39_RS12330	COG0459	protein refolding
CFK39_RS12375	COG0516	GMP reductase activity
CFK39_RS12390	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CFK39_RS12405	COG1175	transmembrane transport
CFK39_RS12410	COG0395	ABC-type sugar transport system, permease component
CFK39_RS12430	COG2271	Major facilitator Superfamily
CFK39_RS12445	COG0477	Major facilitator Superfamily
CFK39_RS12460	COG0588	phosphoglycerate mutase activity
CFK39_RS12465	COG1490	D-aminoacyl-tRNA deacylase activity
CFK39_RS12480	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CFK39_RS12505	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CFK39_RS12545	COG0346	lactoylglutathione lyase activity
CFK39_RS12565	COG0045	succinate-CoA ligase (ADP-forming) activity
CFK39_RS12575	COG1321	iron dependent repressor
CFK39_RS12580	COG0791	NLP P60 protein
CFK39_RS12600	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CFK39_RS12610	COG1316	TRANSCRIPTIONal
CFK39_RS12620	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CFK39_RS12625	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CFK39_RS12630	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CFK39_RS12640	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CFK39_RS12640	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CFK39_RS12650	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CFK39_RS12665	COG0745	RESPONSE REGULATOR receiver
CFK39_RS12670	COG5002	protein histidine kinase activity
CFK39_RS12685	COG1316	TRANSCRIPTIONal
CFK39_RS12700	COG0242	peptide deformylase activity
CFK39_RS12735	COG1136	(ABC) transporter
CFK39_RS12770	COG0544	peptidyl-prolyl cis-trans isomerase activity
CFK39_RS12780	COG0791	NLP P60 protein
CFK39_RS12780	COG1388	LysM domain
CFK39_RS12780	COG3103	Sh3 type 3 domain protein
CFK39_RS12785	COG0740	serine-type endopeptidase activity
CFK39_RS12790	COG0740	serine-type endopeptidase activity
CFK39_RS12795	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CFK39_RS12800	COG0287	Prephenate dehydrogenase
CFK39_RS12800	COG1605	Chorismate mutase
CFK39_RS12805	COG0243	molybdopterin cofactor binding
CFK39_RS12805	COG3383	formate dehydrogenase (NAD+) activity
CFK39_RS12815	COG0437	4 iron, 4 sulfur cluster binding
CFK39_RS12855	COG0525	valine-tRNA ligase activity
CFK39_RS12865	COG0095	Lipoate-protein ligase
CFK39_RS12875	COG0640	Transcriptional regulator
CFK39_RS12890	COG1132	(ABC) transporter
CFK39_RS12910	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CFK39_RS12960	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CFK39_RS12980	COG0228	four-way junction DNA binding
CFK39_RS12985	COG1837	Belongs to the UPF0109 family
CFK39_RS12995	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CFK39_RS13000	COG0336	Belongs to the RNA methyltransferase TrmD family
CFK39_RS13005	COG0335	large ribosomal subunit rRNA binding
CFK39_RS13010	COG0681	Belongs to the peptidase S26 family
CFK39_RS13015	COG0681	Belongs to the peptidase S26 family
CFK39_RS13020	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CFK39_RS13030	COG0792	nuclease activity
CFK39_RS13045	COG4974	Belongs to the 'phage' integrase family
CFK39_RS13055	COG0052	Belongs to the universal ribosomal protein uS2 family
CFK39_RS13060	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CFK39_RS13065	COG0528	UMP kinase activity
CFK39_RS13070	COG0233	cytoplasmic translational termination
CFK39_RS13075	COG0575	Belongs to the CDS family
CFK39_RS13090	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CFK39_RS13100	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CFK39_RS13115	COG0442	prolyl-tRNA aminoacylation
CFK39_RS13125	COG0779	Required for maturation of 30S ribosomal subunits
CFK39_RS13140	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CFK39_RS13140	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CFK39_RS13145	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CFK39_RS13150	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CFK39_RS13165	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CFK39_RS13170	COG1185	polyribonucleotide nucleotidyltransferase activity
CFK39_RS13175	COG0612	Peptidase, M16
CFK39_RS13180	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CFK39_RS13210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFK39_RS13215	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CFK39_RS13220	COG1674	ftsk spoiiie
CFK39_RS13230	COG1058	Belongs to the CinA family
CFK39_RS13230	COG1546	Belongs to the CinA family
CFK39_RS13245	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CFK39_RS13250	COG2137	regulation of response to DNA damage stimulus
CFK39_RS13255	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CFK39_RS13265	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CFK39_RS13270	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CFK39_RS13280	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CFK39_RS13295	COG1388	LysM domain
CFK39_RS13300	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CFK39_RS13315	COG1278	Cold shock
CFK39_RS13330	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFK39_RS13340	COG2001	Belongs to the MraZ family
CFK39_RS13345	COG0275	rRNA processing
CFK39_RS13360	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CFK39_RS13370	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CFK39_RS13375	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CFK39_RS13385	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CFK39_RS13395	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CFK39_RS13400	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CFK39_RS13410	COG1799	cell septum assembly
CFK39_RS13450	COG1175	transmembrane transport
CFK39_RS13455	COG0395	ABC-type sugar transport system, permease component
CFK39_RS13480	COG1090	epimerase
CFK39_RS13485	COG0205	6-phosphofructokinase activity
CFK39_RS13490	COG0166	Belongs to the GPI family
CFK39_RS13500	COG0601	transmembrane transport
CFK39_RS13505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFK39_RS13555	COG2171	N-acyltransferase activity
CFK39_RS13575	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFK39_RS13580	COG1611	Belongs to the LOG family
CFK39_RS13600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CFK39_RS13615	COG2239	Acts as a magnesium transporter
CFK39_RS13620	COG0006	proline dipeptidase activity
CFK39_RS13630	COG0513	Belongs to the DEAD box helicase family
CFK39_RS13645	COG1309	transcriptional regulator
CFK39_RS13725	COG0058	SHG alpha-glucan phosphorylase activity
CFK39_RS13730	COG1653	transport
CFK39_RS13740	COG1946	Acyl-CoA thioesterase
CFK39_RS13755	COG0668	transmembrane transport
CFK39_RS13775	COG4585	Histidine kinase
CFK39_RS13780	COG2197	response regulator
CFK39_RS13785	COG0515	serine threonine protein kinase
CFK39_RS13795	COG1132	(ABC) transporter
CFK39_RS13800	COG1132	(ABC) transporter
CFK39_RS13805	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CFK39_RS13810	COG0698	ribose 5-phosphate isomerase
CFK39_RS13820	COG2267	carboxylic ester hydrolase activity
CFK39_RS13825	COG0590	tRNA wobble adenosine to inosine editing
CFK39_RS13840	COG1122	ATPase activity
CFK39_RS13845	COG4721	ABC-type cobalt transport system, permease component
CFK39_RS13865	COG1397	ADP-ribosylglycohydrolase
CFK39_RS13875	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CFK39_RS13880	COG0438	transferase activity, transferring glycosyl groups
CFK39_RS13900	COG2197	response regulator
CFK39_RS13925	COG2318	DinB family
CFK39_RS13935	COG2186	Transcriptional regulator
CFK39_RS13950	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CFK39_RS14010	COG2814	Major facilitator Superfamily
CFK39_RS14025	COG0443	Heat shock 70 kDa protein
CFK39_RS14030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CFK39_RS14040	COG0789	Transcriptional regulator
CFK39_RS14050	COG0398	Pfam SNARE associated Golgi protein
CFK39_RS14055	COG0438	transferase activity, transferring glycosyl groups
CFK39_RS14060	COG1881	PFAM PEBP family protein
CFK39_RS14085	COG3833	ABC-type maltose transport systems, permease component
CFK39_RS14095	COG2182	Extracellular solute-binding protein
CFK39_RS14105	COG0180	Tryptophanyl-tRNA synthetase
CFK39_RS14115	COG1045	serine acetyltransferase
CFK39_RS14120	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CFK39_RS14130	COG2235	arginine
CFK39_RS14140	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFK39_RS14145	COG0509	glycine decarboxylation via glycine cleavage system
CFK39_RS14150	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CFK39_RS14150	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CFK39_RS14165	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CFK39_RS14175	COG0813	purine-nucleoside phosphorylase activity
CFK39_RS14185	COG0009	L-threonylcarbamoyladenylate synthase
CFK39_RS14205	COG0154	amidase activity
CFK39_RS14220	COG0542	response to heat
CFK39_RS14240	COG0495	leucyl-tRNA aminoacylation
CFK39_RS14250	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CFK39_RS14255	COG0513	Belongs to the DEAD box helicase family
CFK39_RS14260	COG1760	l-serine dehydratase
CFK39_RS14270	COG1902	pentaerythritol trinitrate reductase activity
CFK39_RS14275	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFK39_RS14285	COG2197	response regulator
CFK39_RS14290	COG4585	Histidine kinase
CFK39_RS14305	COG0215	cysteine-tRNA ligase activity
CFK39_RS14310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFK39_RS14315	COG2364	Membrane
CFK39_RS14325	COG3842	ATPase activity
CFK39_RS14330	COG0242	peptide deformylase activity
CFK39_RS14340	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CFK39_RS14345	COG2027	D-alanyl-D-alanine carboxypeptidase
CFK39_RS14350	COG0037	tRNA processing
CFK39_RS14365	COG0302	gtp cyclohydrolase
CFK39_RS14370	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CFK39_RS14405	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CFK39_RS14420	COG2017	converts alpha-aldose to the beta-anomer
CFK39_RS14425	COG1556	Lactate utilization protein
CFK39_RS14430	COG1139	Iron-sulfur cluster binding protein
CFK39_RS14435	COG0247	lactate metabolic process
CFK39_RS14465	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CFK39_RS14515	COG0483	inositol monophosphate 1-phosphatase activity
CFK39_RS14535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFK39_RS14545	COG1854	S-ribosylhomocysteine lyase activity
CFK39_RS14570	COG0084	hydrolase, TatD family'
CFK39_RS14575	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CFK39_RS14580	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CFK39_RS14590	COG0488	(ABC) transporter
CFK39_RS14600	COG1309	transcriptional regulator
CFK39_RS14610	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CFK39_RS14615	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CFK39_RS14620	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CFK39_RS14625	COG0193	aminoacyl-tRNA hydrolase activity
CFK39_RS14640	COG0148	phosphopyruvate hydratase activity
CFK39_RS14660	COG1252	NADH dehydrogenase
CFK39_RS14665	COG0363	glucosamine-6-phosphate deaminase activity
CFK39_RS14670	COG2252	PERMEase
CFK39_RS14680	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CFK39_RS14685	COG2226	methyltransferase
CFK39_RS14710	COG0647	UMP catabolic process
CFK39_RS14720	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CFK39_RS14725	COG0497	DNA recombination
CFK39_RS14755	COG0504	CTP synthase activity
CFK39_RS14765	COG1129	ABC transporter
CFK39_RS14770	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFK39_RS14790	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CFK39_RS14800	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFK39_RS14890	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CFK39_RS14905	COG0217	transcriptional regulatory protein
CFK39_RS14910	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CFK39_RS14920	COG2255	four-way junction helicase activity
CFK39_RS14935	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CFK39_RS14940	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CFK39_RS14955	COG1196	nuclear chromosome segregation
CFK39_RS14960	COG0124	histidyl-tRNA synthetase
CFK39_RS14965	COG3118	belongs to the thioredoxin family
CFK39_RS14975	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CFK39_RS14985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFK39_RS15000	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CFK39_RS15005	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFK39_RS15020	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CFK39_RS15030	COG2010	Cytochrome c
CFK39_RS15035	COG1845	cytochrome c oxidase, subunit III
CFK39_RS15040	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CFK39_RS15060	COG1940	carbohydrate kinase activity
CFK39_RS15080	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CFK39_RS15085	COG0515	serine threonine protein kinase
CFK39_RS15085	COG2815	serine threonine protein kinase
CFK39_RS15105	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CFK39_RS15115	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFK39_RS15130	COG0187	DNA topoisomerase II activity
CFK39_RS15135	COG0107	imidazoleglycerol-phosphate synthase activity
CFK39_RS15145	COG1136	(ABC) transporter
CFK39_RS15165	COG0676	glucose-6-phosphate 1-epimerase activity
CFK39_RS15175	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFK39_RS15210	COG0756	dUTP diphosphatase activity
CFK39_RS15225	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CFK39_RS15230	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CFK39_RS15235	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CFK39_RS15240	COG0024	Methionine aminopeptidase
CFK39_RS15260	COG0435	Glutathione S-transferase
CFK39_RS15285	COG0396	ATPase activity
CFK39_RS15290	COG2151	metal-sulfur cluster biosynthetic enzyme
CFK39_RS15295	COG0488	(ABC) transporter
CFK39_RS15305	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CFK39_RS15310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CFK39_RS15315	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CFK39_RS15325	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CFK39_RS15335	COG0505	Belongs to the CarA family
CFK39_RS15345	COG0284	orotidine-5'-phosphate decarboxylase activity
CFK39_RS15355	COG0194	GDP metabolic process
CFK39_RS15360	COG1758	RNA polymerase activity
CFK39_RS15370	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CFK39_RS15375	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CFK39_RS15400	COG0134	indole-3-glycerol-phosphate synthase activity
CFK39_RS15405	COG0133	tryptophan synthase activity
CFK39_RS15410	COG0159	tryptophan synthase activity
CFK39_RS15420	COG0069	glutamate synthase activity
CFK39_RS15420	COG0070	glutamate synthase
CFK39_RS15420	COG0067	glutamate synthase
CFK39_RS15430	COG0469	pyruvate kinase activity
CFK39_RS15435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFK39_RS15465	COG0539	negative regulation of cytoplasmic translation
CFK39_RS15475	COG0484	heat shock protein binding
CFK39_RS15670	COG1192	Involved in chromosome partitioning
CFK39_RS15890	COG1192	Involved in chromosome partitioning
CFK39_RS15920	COG1475	DNA binding
CFK39_RS15935	COG1525	nuclease
CFK39_RS15950	COG2186	Transcriptional regulator
CFK39_RS15970	COG2135	peptidase activity
CFK39_RS15980	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CFK39_RS15985	COG0629	single-stranded DNA binding
CFK39_RS16010	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFK39_RS16075	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system