locus-tag	class	description
CFK41_RS00010	COG0693	protein deglycase activity
CFK41_RS00030	COG1253	flavin adenine dinucleotide binding
CFK41_RS00040	COG0738	Major facilitator superfamily
CFK41_RS00045	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CFK41_RS00060	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CFK41_RS00070	COG0402	S-adenosylhomocysteine deaminase activity
CFK41_RS00100	COG2217	Heavy metal translocating P-type atpase
CFK41_RS00120	COG4941	Belongs to the sigma-70 factor family
CFK41_RS00125	COG3795	YCII-related domain
CFK41_RS00145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CFK41_RS00150	COG0667	Aldo Keto reductase
CFK41_RS00165	COG4335	DNA alkylation repair
CFK41_RS00245	COG1113	amino acid transport
CFK41_RS00280	COG0477	Major facilitator Superfamily
CFK41_RS00345	COG0803	Belongs to the bacterial solute-binding protein 9 family
CFK41_RS00350	COG1121	(ABC) transporter
CFK41_RS00360	COG1321	iron dependent repressor
CFK41_RS00400	COG1606	tRNA processing
CFK41_RS00405	COG1691	(AIR) carboxylase
CFK41_RS00410	COG3654	unkown
CFK41_RS00425	COG1609	Transcriptional regulator
CFK41_RS00430	COG1904	glucuronate isomerase
CFK41_RS00435	COG0246	Mannitol dehydrogenase
CFK41_RS00445	COG2197	response regulator
CFK41_RS00470	COG2847	Copper chaperone PCu(A)C
CFK41_RS00495	COG0583	DNA-binding transcription factor activity
CFK41_RS00515	COG4946	Tricorn protease homolog
CFK41_RS00515	COG0793	Belongs to the peptidase S41A family
CFK41_RS00540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFK41_RS00545	COG1064	alcohol dehydrogenase
CFK41_RS00550	COG1309	transcriptional regulator
CFK41_RS00555	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CFK41_RS00560	COG1528	Iron-storage protein
CFK41_RS00565	COG1609	Transcriptional regulator
CFK41_RS00570	COG1175	transmembrane transport
CFK41_RS00590	COG0584	glycerophosphoryl diester phosphodiesterase
CFK41_RS00600	COG1476	TRANSCRIPTIONal
CFK41_RS00605	COG3291	Pkd domain containing protein
CFK41_RS00605	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CFK41_RS00610	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CFK41_RS00635	COG2318	DinB family
CFK41_RS00650	COG0010	Belongs to the arginase family
CFK41_RS00675	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CFK41_RS00680	COG1228	amidohydrolase
CFK41_RS00685	COG3314	Sporulation integral membrane protein YlbJ
CFK41_RS00690	COG2986	histidine ammonia-lyase
CFK41_RS00725	COG1028	Short-chain dehydrogenase reductase Sdr
CFK41_RS00775	COG0586	Pfam SNARE associated Golgi protein
CFK41_RS00810	COG0531	amino acid
CFK41_RS00815	COG0589	response to stress
CFK41_RS00825	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CFK41_RS00835	COG0477	Major facilitator Superfamily
CFK41_RS00840	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CFK41_RS00840	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CFK41_RS00850	COG0384	phenazine biosynthesis protein PhzF
CFK41_RS00860	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CFK41_RS00865	COG0386	Belongs to the glutathione peroxidase family
CFK41_RS00910	COG0259	pyridoxamine-phosphate oxidase activity
CFK41_RS00925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFK41_RS00925	COG1263	PTS System
CFK41_RS00925	COG2190	(PTS) system
CFK41_RS00940	COG0183	Belongs to the thiolase family
CFK41_RS01020	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFK41_RS01020	COG1024	Enoyl-CoA hydratase
CFK41_RS01045	COG0351	phosphomethylpyrimidine kinase
CFK41_RS01050	COG1126	abc transporter atp-binding protein
CFK41_RS01055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFK41_RS01060	COG0765	amino acid transport
CFK41_RS01065	COG0765	amino acid transport
CFK41_RS01075	COG0517	IMP dehydrogenase activity
CFK41_RS01075	COG1125	glycine betaine transport
CFK41_RS01080	COG1174	glycine betaine transport
CFK41_RS01095	COG0702	epimerase
CFK41_RS01110	COG0640	Transcriptional regulator
CFK41_RS01120	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CFK41_RS01135	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CFK41_RS01140	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CFK41_RS01145	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CFK41_RS01150	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CFK41_RS01180	COG1069	ribulokinase activity
CFK41_RS01190	COG1063	alcohol dehydrogenase
CFK41_RS01195	COG2814	Major facilitator Superfamily
CFK41_RS01205	COG0477	Major facilitator Superfamily
CFK41_RS01215	COG1984	allophanate hydrolase subunit 2
CFK41_RS01220	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CFK41_RS01235	COG0601	transmembrane transport
CFK41_RS01240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFK41_RS01265	COG0586	Pfam SNARE associated Golgi protein
CFK41_RS01295	COG1175	transmembrane transport
CFK41_RS01300	COG0395	ABC-type sugar transport system, permease component
CFK41_RS01305	COG0673	inositol 2-dehydrogenase activity
CFK41_RS01325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFK41_RS01335	COG4608	Belongs to the ABC transporter superfamily
CFK41_RS01355	COG3250	beta-galactosidase activity
CFK41_RS01365	COG1175	transmembrane transport
CFK41_RS01375	COG1609	Transcriptional regulator
CFK41_RS01380	COG1070	Carbohydrate kinase
CFK41_RS01385	COG3347	Dehydrogenase
CFK41_RS01385	COG1028	Short-chain dehydrogenase reductase Sdr
CFK41_RS01400	COG0673	inositol 2-dehydrogenase activity
CFK41_RS01415	COG0395	ABC-type sugar transport system, permease component
CFK41_RS01420	COG4209	transmembrane transport
CFK41_RS01425	COG1609	Transcriptional regulator
CFK41_RS01430	COG1609	Transcriptional regulator
CFK41_RS01440	COG5578	integral membrane protein
CFK41_RS01445	COG1653	transport
CFK41_RS01450	COG4209	transmembrane transport
CFK41_RS01455	COG0395	ABC-type sugar transport system, permease component
CFK41_RS01460	COG3401	FG-GAP repeat protein
CFK41_RS01475	COG0657	acetylesterase activity
CFK41_RS01490	COG4209	transmembrane transport
CFK41_RS01495	COG0395	ABC-type sugar transport system, permease component
CFK41_RS01515	COG1940	carbohydrate kinase activity
CFK41_RS01530	COG0395	ABC-type sugar transport system, permease component
CFK41_RS01535	COG1175	transmembrane transport
CFK41_RS01560	COG0277	FAD linked oxidase domain protein
CFK41_RS01565	COG2160	L-arabinose isomerase activity
CFK41_RS01575	COG1069	ribulokinase activity
CFK41_RS01580	COG1609	Transcriptional regulator
CFK41_RS01585	COG4213	ABC transporter substrate-binding protein
CFK41_RS01595	COG4214	carbohydrate transport
CFK41_RS01605	COG1175	transmembrane transport
CFK41_RS01610	COG0395	ABC-type sugar transport system, permease component
CFK41_RS01615	COG2182	Extracellular solute-binding protein
CFK41_RS01625	COG0395	ABC-type sugar transport system, permease component
CFK41_RS01640	COG1175	transmembrane transport
CFK41_RS01645	COG0395	ABC-type sugar transport system, permease component
CFK41_RS01650	COG3507	Belongs to the glycosyl hydrolase 43 family
CFK41_RS01660	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CFK41_RS01675	COG3534	alpha-L-arabinofuranosidase
CFK41_RS01705	COG2755	lipolytic protein G-D-S-L family
CFK41_RS01710	COG1609	Transcriptional regulator
CFK41_RS01720	COG4209	transmembrane transport
CFK41_RS01750	COG0395	ABC-type sugar transport system, permease component
CFK41_RS01755	COG4677	pectinesterase activity
CFK41_RS01780	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CFK41_RS01805	COG0563	adenylate kinase activity
CFK41_RS01810	COG1902	pentaerythritol trinitrate reductase activity
CFK41_RS01815	COG0640	Transcriptional regulator
CFK41_RS01830	COG0673	inositol 2-dehydrogenase activity
CFK41_RS01850	COG1609	Transcriptional regulator
CFK41_RS01865	COG2814	Major facilitator Superfamily
CFK41_RS01875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFK41_RS01900	COG0823	Involved in the tonB-independent uptake of proteins
CFK41_RS01900	COG1506	peptidase
CFK41_RS01925	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CFK41_RS01935	COG0733	neurotransmitter:sodium symporter activity
CFK41_RS01955	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CFK41_RS01965	COG0519	Catalyzes the synthesis of GMP from XMP
CFK41_RS01970	COG1380	Effector of murein hydrolase LrgA
CFK41_RS01975	COG1346	cytolysis
CFK41_RS01990	COG0798	PFAM Bile acid sodium symporter
CFK41_RS01995	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CFK41_RS02015	COG2814	Major facilitator Superfamily
CFK41_RS02020	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CFK41_RS02025	COG0569	domain protein
CFK41_RS02055	COG4585	Histidine kinase
CFK41_RS02060	COG2197	response regulator
CFK41_RS02080	COG1309	transcriptional regulator
CFK41_RS02100	COG0667	Aldo Keto reductase
CFK41_RS02105	COG1115	amino acid carrier protein
CFK41_RS02130	COG1823	symporter activity
CFK41_RS02170	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CFK41_RS02185	COG4555	ABC transporter
CFK41_RS02190	COG1653	transport
CFK41_RS02195	COG0395	ABC-type sugar transport system, permease component
CFK41_RS02200	COG1175	transmembrane transport
CFK41_RS02210	COG4221	oxidoreductase activity
CFK41_RS02235	COG1309	transcriptional regulator
CFK41_RS02250	COG3158	transport of potassium into the cell
CFK41_RS02255	COG1940	carbohydrate kinase activity
CFK41_RS02260	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFK41_RS02275	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CFK41_RS02305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFK41_RS02330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFK41_RS02335	COG1937	Protein conserved in bacteria
CFK41_RS02365	COG1609	Transcriptional regulator
CFK41_RS02375	COG4209	transmembrane transport
CFK41_RS02380	COG0395	ABC-type sugar transport system, permease component
CFK41_RS02405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFK41_RS02410	COG4521	taurine ABC transporter
CFK41_RS02415	COG1116	anion transmembrane transporter activity
CFK41_RS02420	COG0438	transferase activity, transferring glycosyl groups
CFK41_RS02435	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CFK41_RS02465	COG2081	HI0933 family
CFK41_RS02495	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CFK41_RS02515	COG0745	RESPONSE REGULATOR receiver
CFK41_RS02525	COG2205	protein histidine kinase activity
CFK41_RS02525	COG2202	Pas domain
CFK41_RS02615	COG1752	Esterase of the alpha-beta hydrolase superfamily
CFK41_RS02650	COG1028	Short-chain dehydrogenase reductase Sdr
CFK41_RS02670	COG0673	inositol 2-dehydrogenase activity
CFK41_RS02685	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CFK41_RS02700	COG0714	Associated with various cellular activities
CFK41_RS02730	COG0395	ABC-type sugar transport system, permease component
CFK41_RS02735	COG4209	transmembrane transport
CFK41_RS02740	COG0673	inositol 2-dehydrogenase activity
CFK41_RS02745	COG1252	NADH dehydrogenase
CFK41_RS02750	COG4085	toxin activity
CFK41_RS02750	COG1525	nuclease
CFK41_RS02750	COG0737	Belongs to the 5'-nucleotidase family
CFK41_RS02800	COG0352	thiamine-phosphate diphosphorylase activity
CFK41_RS02805	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CFK41_RS02815	COG0351	phosphomethylpyrimidine kinase
CFK41_RS02815	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CFK41_RS02815	COG0352	thiamine-phosphate diphosphorylase activity
CFK41_RS02825	COG0420	3'-5' exonuclease activity
CFK41_RS02830	COG0419	ATPase involved in DNA repair
CFK41_RS02835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFK41_RS02850	COG1132	(ABC) transporter
CFK41_RS02855	COG1132	(ABC) transporter
CFK41_RS02885	COG0765	amino acid transport
CFK41_RS02935	COG0673	inositol 2-dehydrogenase activity
CFK41_RS02950	COG0640	Transcriptional regulator
CFK41_RS02975	COG3764	Sortase (surface protein transpeptidase)
CFK41_RS02990	COG0515	serine threonine protein kinase
CFK41_RS02995	COG0515	serine threonine protein kinase
CFK41_RS03000	COG0768	penicillin binding
CFK41_RS03015	COG1716	ATPase activity
CFK41_RS03030	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CFK41_RS03050	COG0438	transferase activity, transferring glycosyl groups
CFK41_RS03060	COG0791	NLP P60 protein
CFK41_RS03060	COG3103	Sh3 type 3 domain protein
CFK41_RS03060	COG1388	LysM domain
CFK41_RS03065	COG1116	anion transmembrane transporter activity
CFK41_RS03075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFK41_RS03080	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFK41_RS03095	COG1832	CoA-binding protein
CFK41_RS03135	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CFK41_RS03140	COG0113	porphobilinogen synthase activity
CFK41_RS03150	COG0181	hydroxymethylbilane synthase activity
CFK41_RS03155	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CFK41_RS03160	COG3253	May function as heme-dependent peroxidase
CFK41_RS03170	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CFK41_RS03175	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CFK41_RS03190	COG2755	lipolytic protein G-D-S-L family
CFK41_RS03190	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CFK41_RS03195	COG1362	aminopeptidase activity
CFK41_RS03205	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CFK41_RS03215	COG0343	queuine tRNA-ribosyltransferase activity
CFK41_RS03240	COG0477	Major facilitator Superfamily
CFK41_RS03270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFK41_RS03275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFK41_RS03280	COG1120	ATPase activity
CFK41_RS03290	COG1215	transferase activity, transferring glycosyl groups
CFK41_RS03300	COG1215	transferase activity, transferring glycosyl groups
CFK41_RS03315	COG1134	teichoic acid transport
CFK41_RS03320	COG0300	oxidoreductase activity
CFK41_RS03325	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CFK41_RS03335	COG1216	Glycosyl transferase, family 2
CFK41_RS03360	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CFK41_RS03375	COG1408	metallophosphoesterase
CFK41_RS03420	COG1278	Cold shock
CFK41_RS03430	COG0470	DNA polymerase III
CFK41_RS03445	COG0395	ABC-type sugar transport system, permease component
CFK41_RS03450	COG1175	transmembrane transport
CFK41_RS03455	COG1653	transport
CFK41_RS03460	COG1754	DNA topoisomerase type I activity
CFK41_RS03460	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CFK41_RS03470	COG2890	protein-(glutamine-N5) methyltransferase activity
CFK41_RS03475	COG1205	dead DEAH box helicase
CFK41_RS03475	COG1111	helicase
CFK41_RS03510	COG0708	Exodeoxyribonuclease III
CFK41_RS03515	COG0300	oxidoreductase activity
CFK41_RS03520	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CFK41_RS03530	COG0586	Pfam SNARE associated Golgi protein
CFK41_RS03550	COG4129	membrane
CFK41_RS03560	COG0354	folic acid binding
CFK41_RS03580	COG0456	acetyltransferase
CFK41_RS03610	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CFK41_RS03615	COG1136	(ABC) transporter
CFK41_RS03640	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CFK41_RS03645	COG1950	PFAM Membrane protein of
CFK41_RS03655	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CFK41_RS03675	COG5002	protein histidine kinase activity
CFK41_RS03690	COG0745	RESPONSE REGULATOR receiver
CFK41_RS03695	COG1472	Belongs to the glycosyl hydrolase 3 family
CFK41_RS03700	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CFK41_RS03710	COG0022	dehydrogenase e1 component
CFK41_RS03715	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFK41_RS03720	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CFK41_RS03725	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CFK41_RS03735	COG2072	flavoprotein involved in K transport
CFK41_RS03745	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CFK41_RS03750	COG0488	(ABC) transporter
CFK41_RS03760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFK41_RS03765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFK41_RS03780	COG1309	transcriptional regulator
CFK41_RS03790	COG0717	Belongs to the dCTP deaminase family
CFK41_RS03805	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CFK41_RS03805	COG2111	Na H antiporter
CFK41_RS03810	COG1006	Multisubunit Na H antiporter MnhC subunit
CFK41_RS03815	COG0651	ATP synthesis coupled electron transport
CFK41_RS03835	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CFK41_RS03845	COG4941	Belongs to the sigma-70 factor family
CFK41_RS03850	COG3795	YCII-related domain
CFK41_RS03860	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CFK41_RS03880	COG2197	response regulator
CFK41_RS03885	COG4585	Histidine kinase
CFK41_RS03910	COG4221	oxidoreductase activity
CFK41_RS03915	COG1028	Short-chain dehydrogenase reductase Sdr
CFK41_RS03945	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CFK41_RS03950	COG1780	Probably involved in ribonucleotide reductase function
CFK41_RS03955	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFK41_RS03995	COG0477	Major facilitator Superfamily
CFK41_RS04000	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFK41_RS04025	COG1739	Uncharacterized protein family UPF0029
CFK41_RS04035	COG1917	Cupin 2, conserved barrel domain protein
CFK41_RS04045	COG0456	acetyltransferase
CFK41_RS04050	COG1115	amino acid carrier protein
CFK41_RS04120	COG0477	Major facilitator Superfamily
CFK41_RS04130	COG2814	Major facilitator Superfamily
CFK41_RS04165	COG2197	response regulator
CFK41_RS04170	COG4585	Histidine kinase
CFK41_RS04175	COG0395	ABC-type sugar transport system, permease component
CFK41_RS04180	COG1175	transmembrane transport
CFK41_RS04190	COG1940	carbohydrate kinase activity
CFK41_RS04190	COG1846	Transcriptional regulator
CFK41_RS04195	COG0673	inositol 2-dehydrogenase activity
CFK41_RS04205	COG4176	ABC-type proline glycine betaine transport system permease component
CFK41_RS04215	COG0412	Dienelactone hydrolase
CFK41_RS04220	COG0387	Pfam Sodium calcium exchanger
CFK41_RS04230	COG0659	secondary active sulfate transmembrane transporter activity
CFK41_RS04240	COG1506	peptidase
CFK41_RS04240	COG0823	Involved in the tonB-independent uptake of proteins
CFK41_RS04255	COG2372	response to copper ion
CFK41_RS04265	COG1349	DNA-binding transcription factor activity
CFK41_RS04285	COG0569	domain protein
CFK41_RS04290	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CFK41_RS04295	COG0123	including yeast histone deacetylase and acetoin utilization protein
CFK41_RS04310	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CFK41_RS04325	COG2353	YceI-like domain
CFK41_RS04335	COG0406	alpha-ribazole phosphatase activity
CFK41_RS04355	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CFK41_RS04380	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CFK41_RS04395	COG4948	Mandelate Racemase Muconate Lactonizing
CFK41_RS04400	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CFK41_RS04405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFK41_RS04410	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CFK41_RS04435	COG2326	polyphosphate kinase activity
CFK41_RS04440	COG1027	Aspartate ammonia-lyase
CFK41_RS04460	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CFK41_RS04465	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CFK41_RS04470	COG0436	Aminotransferase
CFK41_RS04480	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CFK41_RS04485	COG0250	Participates in transcription elongation, termination and antitermination
CFK41_RS04490	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CFK41_RS04495	COG0081	regulation of translation
CFK41_RS04505	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CFK41_RS04515	COG0085	RNA polymerase activity
CFK41_RS04520	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CFK41_RS04525	COG3583	domain protein
CFK41_RS04530	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CFK41_RS04535	COG0049	tRNA binding
CFK41_RS04540	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CFK41_RS04545	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFK41_RS04555	COG1653	transport
CFK41_RS04560	COG1175	transmembrane transport
CFK41_RS04565	COG0395	ABC-type sugar transport system, permease component
CFK41_RS04570	COG0051	transcription antitermination factor activity, RNA binding
CFK41_RS04575	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CFK41_RS04580	COG0088	Forms part of the polypeptide exit tunnel
CFK41_RS04585	COG0089	rRNA binding
CFK41_RS04590	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CFK41_RS04595	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CFK41_RS04600	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CFK41_RS04605	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CFK41_RS04610	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CFK41_RS04615	COG0255	Belongs to the universal ribosomal protein uL29 family
CFK41_RS04620	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CFK41_RS04625	COG0477	Major facilitator Superfamily
CFK41_RS04635	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CFK41_RS04640	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CFK41_RS04645	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CFK41_RS04650	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CFK41_RS04655	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CFK41_RS04660	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CFK41_RS04665	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CFK41_RS04670	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CFK41_RS04675	COG1841	ribosomal large subunit assembly
CFK41_RS04680	COG0200	Binds to the 23S rRNA
CFK41_RS04685	COG0201	protein transport
CFK41_RS04690	COG0563	adenylate kinase activity
CFK41_RS04700	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CFK41_RS04705	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CFK41_RS04710	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CFK41_RS04715	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CFK41_RS04720	COG0202	RNA polymerase activity
CFK41_RS04725	COG0203	ribosomal protein L17
CFK41_RS04755	COG0738	Major facilitator superfamily
CFK41_RS04760	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CFK41_RS04770	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFK41_RS04785	COG0183	Belongs to the thiolase family
CFK41_RS04790	COG1028	Short-chain dehydrogenase reductase Sdr
CFK41_RS04810	COG0789	Transcriptional regulator
CFK41_RS04820	COG1741	Belongs to the pirin family
CFK41_RS04825	COG2813	Specifically methylates the guanine in position
CFK41_RS04835	COG0047	phosphoribosylformylglycinamidine synthase activity
CFK41_RS04840	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFK41_RS04860	COG3845	ABC transporter
CFK41_RS04865	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CFK41_RS04870	COG0151	Belongs to the GarS family
CFK41_RS04875	COG0101	tRNA pseudouridine synthase activity
CFK41_RS04880	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CFK41_RS04885	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CFK41_RS04890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFK41_RS04895	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CFK41_RS04900	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFK41_RS04905	COG1072	(Pantothenic acid kinase))
CFK41_RS04910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CFK41_RS04915	COG0736	holo-[acyl-carrier-protein] synthase activity
CFK41_RS04925	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CFK41_RS04930	COG0802	atpase or kinase
CFK41_RS04935	COG1214	PFAM Peptidase M22, glycoprotease
CFK41_RS04960	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CFK41_RS04970	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CFK41_RS04985	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CFK41_RS04990	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CFK41_RS05000	COG0114	fumarate hydratase activity
CFK41_RS05015	COG0471	metal ion transport
CFK41_RS05020	COG1929	Belongs to the glycerate kinase type-1 family
CFK41_RS05025	COG1722	exodeoxyribonuclease VII activity
CFK41_RS05045	COG1322	Protein conserved in bacteria
CFK41_RS05050	COG1733	regulation of RNA biosynthetic process
CFK41_RS05055	COG2910	NAD(P)H-binding
CFK41_RS05100	COG1028	Short-chain dehydrogenase reductase Sdr
CFK41_RS05150	COG0789	Transcriptional regulator
CFK41_RS05155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFK41_RS05160	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFK41_RS05170	COG0454	-acetyltransferase
CFK41_RS05190	COG1054	Belongs to the UPF0176 family
CFK41_RS05195	COG3655	Transcriptional regulator
CFK41_RS05215	COG0456	acetyltransferase
CFK41_RS05225	COG0259	pyridoxamine-phosphate oxidase activity
CFK41_RS05280	COG1126	abc transporter atp-binding protein
CFK41_RS05285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFK41_RS05290	COG0765	amino acid transport
CFK41_RS05295	COG0765	amino acid transport
CFK41_RS05320	COG2154	pterin-4-alpha-carbinolamine dehydratase
CFK41_RS05325	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CFK41_RS05340	COG0488	(ABC) transporter
CFK41_RS05345	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFK41_RS05360	COG1012	belongs to the aldehyde dehydrogenase family
CFK41_RS05365	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CFK41_RS05370	COG2814	Major facilitator Superfamily
CFK41_RS05425	COG2211	Major facilitator Superfamily
CFK41_RS05435	COG3173	Aminoglycoside phosphotransferase
CFK41_RS05445	COG1120	ATPase activity
CFK41_RS05450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFK41_RS05455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFK41_RS05470	COG1435	thymidine kinase activity
CFK41_RS05490	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFK41_RS05490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFK41_RS05490	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFK41_RS05495	COG1105	Belongs to the carbohydrate kinase PfkB family
CFK41_RS05500	COG1349	DNA-binding transcription factor activity
CFK41_RS05525	COG1649	PFAM Uncharacterised BCR, COG1649
CFK41_RS05530	COG2354	Protein conserved in bacteria
CFK41_RS05545	COG1254	Belongs to the acylphosphatase family
CFK41_RS05550	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CFK41_RS05560	COG2326	polyphosphate kinase activity
CFK41_RS05565	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CFK41_RS05570	COG3189	MarR family transcriptional regulator
CFK41_RS05585	COG2838	Isocitrate dehydrogenase
CFK41_RS05595	COG0428	transporter
CFK41_RS05600	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CFK41_RS05605	COG1609	Transcriptional regulator
CFK41_RS05610	COG1653	transport
CFK41_RS05620	COG0395	ABC-type sugar transport system, permease component
CFK41_RS05640	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CFK41_RS05645	COG0131	Imidazoleglycerol-phosphate dehydratase
CFK41_RS05655	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CFK41_RS05665	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CFK41_RS05685	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CFK41_RS05690	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CFK41_RS05695	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CFK41_RS05700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFK41_RS05730	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CFK41_RS05735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFK41_RS05735	COG0072	phenylalanine-tRNA ligase activity
CFK41_RS05745	COG3064	Membrane
CFK41_RS05745	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CFK41_RS05745	COG3583	domain protein
CFK41_RS05755	COG0747	negative chemotaxis
CFK41_RS05760	COG4608	Belongs to the ABC transporter superfamily
CFK41_RS05765	COG0444	Belongs to the ABC transporter superfamily
CFK41_RS05770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFK41_RS05775	COG0601	transmembrane transport
CFK41_RS05785	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CFK41_RS05790	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CFK41_RS05795	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CFK41_RS05800	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CFK41_RS05810	COG1438	arginine binding
CFK41_RS05815	COG0137	argininosuccinate synthase activity
CFK41_RS05820	COG0165	Argininosuccinate lyase
CFK41_RS05825	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CFK41_RS05845	COG0142	geranyltranstransferase activity
CFK41_RS05855	COG0714	Associated with various cellular activities
CFK41_RS05875	COG0631	protein serine/threonine phosphatase activity
CFK41_RS05895	COG1674	ftsk spoiiie
CFK41_RS05930	COG1666	GTP binding
CFK41_RS05950	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CFK41_RS05955	COG2030	dehydratase
CFK41_RS05965	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CFK41_RS05970	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CFK41_RS05975	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CFK41_RS05985	COG0596	Alpha beta hydrolase
CFK41_RS05990	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CFK41_RS06005	COG2009	succinate dehydrogenase
CFK41_RS06015	COG1473	amidohydrolase
CFK41_RS06015	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CFK41_RS06020	COG1744	ABC transporter substrate-binding protein PnrA-like
CFK41_RS06025	COG3845	ABC transporter
CFK41_RS06030	COG4603	Belongs to the binding-protein-dependent transport system permease family
CFK41_RS06035	COG1079	Belongs to the binding-protein-dependent transport system permease family
CFK41_RS06055	COG1063	alcohol dehydrogenase
CFK41_RS06060	COG2186	Transcriptional regulator
CFK41_RS06070	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CFK41_RS06080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFK41_RS06095	COG4770	biotin carboxylase activity
CFK41_RS06100	COG0424	maF-like protein
CFK41_RS06115	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CFK41_RS06130	COG0745	RESPONSE REGULATOR receiver
CFK41_RS06135	COG0642	Histidine kinase
CFK41_RS06150	COG1134	teichoic acid transport
CFK41_RS06160	COG0463	Glycosyl transferase, family 2
CFK41_RS06175	COG2089	acid synthase
CFK41_RS06185	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
CFK41_RS06190	COG1086	Polysaccharide biosynthesis protein
CFK41_RS06195	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CFK41_RS06215	COG1316	TRANSCRIPTIONal
CFK41_RS06235	COG1216	Glycosyl transferase, family 2
CFK41_RS06255	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CFK41_RS06255	COG0778	Nitroreductase
CFK41_RS06285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFK41_RS06315	COG0714	Associated with various cellular activities
CFK41_RS06335	COG0745	RESPONSE REGULATOR receiver
CFK41_RS06340	COG5002	protein histidine kinase activity
CFK41_RS06345	COG5401	PFAM Sporulation and spore germination
CFK41_RS06355	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CFK41_RS06365	COG0653	protein targeting
CFK41_RS06425	COG0577	efflux transmembrane transporter activity
CFK41_RS06430	COG1136	(ABC) transporter
CFK41_RS06430	COG4591	ABC-type transport system involved in lipoprotein release permease component
CFK41_RS06435	COG2197	response regulator
CFK41_RS06440	COG4585	Histidine kinase
CFK41_RS06470	COG1204	response to ionizing radiation
CFK41_RS06485	COG1929	Belongs to the glycerate kinase type-1 family
CFK41_RS06490	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CFK41_RS06495	COG2884	Cell division ATP-binding protein ftsE
CFK41_RS06500	COG2177	Part of the ABC transporter FtsEX involved in
CFK41_RS06505	COG0739	heme binding
CFK41_RS06505	COG0741	lytic transglycosylase activity
CFK41_RS06505	COG1196	nuclear chromosome segregation
CFK41_RS06510	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CFK41_RS06535	COG1643	Atp-dependent helicase
CFK41_RS06550	COG3876	Protein conserved in bacteria
CFK41_RS06555	COG0456	acetyltransferase
CFK41_RS06560	COG0747	negative chemotaxis
CFK41_RS06565	COG0601	transmembrane transport
CFK41_RS06575	COG4172	Belongs to the ABC transporter superfamily
CFK41_RS06580	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CFK41_RS06585	COG1737	Transcriptional regulator
CFK41_RS06610	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CFK41_RS06620	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CFK41_RS06625	COG1234	tRNA 3'-trailer cleavage
CFK41_RS06630	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CFK41_RS06635	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CFK41_RS06645	COG0406	alpha-ribazole phosphatase activity
CFK41_RS06655	COG1028	Short-chain dehydrogenase reductase Sdr
CFK41_RS06665	COG3012	SEC-C Motif Domain Protein
CFK41_RS06690	COG0604	alcohol dehydrogenase
CFK41_RS06690	COG3321	synthase
CFK41_RS06700	COG1902	pentaerythritol trinitrate reductase activity
CFK41_RS06710	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CFK41_RS06715	COG1309	transcriptional regulator
CFK41_RS06720	COG1937	Protein conserved in bacteria
CFK41_RS06745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFK41_RS06750	COG2357	RelA SpoT domain protein
CFK41_RS06760	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFK41_RS06825	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CFK41_RS06830	COG1201	RNA secondary structure unwinding
CFK41_RS06835	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CFK41_RS06840	COG0629	single-stranded DNA binding
CFK41_RS06850	COG1615	UPF0182 protein
CFK41_RS06870	COG0205	6-phosphofructokinase activity
CFK41_RS06875	COG0483	inositol monophosphate 1-phosphatase activity
CFK41_RS06880	COG1162	GTPase activity
CFK41_RS06885	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CFK41_RS06895	COG1595	DNA-templated transcription, initiation
CFK41_RS06915	COG0567	Dehydrogenase, E1 component
CFK41_RS06915	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFK41_RS06920	COG2205	protein histidine kinase activity
CFK41_RS06925	COG0745	RESPONSE REGULATOR receiver
CFK41_RS06930	COG0741	lytic transglycosylase activity
CFK41_RS06930	COG0739	heme binding
CFK41_RS06930	COG1196	nuclear chromosome segregation
CFK41_RS06935	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CFK41_RS06955	COG0460	homoserine dehydrogenase
CFK41_RS06960	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CFK41_RS06965	COG0083	homoserine kinase activity
CFK41_RS06975	COG0395	ABC-type sugar transport system, permease component
CFK41_RS07005	COG0254	rRNA binding
CFK41_RS07010	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CFK41_RS07035	COG0356	it plays a direct role in the translocation of protons across the membrane
CFK41_RS07040	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CFK41_RS07045	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CFK41_RS07050	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CFK41_RS07055	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CFK41_RS07060	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CFK41_RS07065	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CFK41_RS07080	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CFK41_RS07085	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CFK41_RS07105	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CFK41_RS07110	COG0366	Alpha amylase catalytic
CFK41_RS07115	COG1523	belongs to the glycosyl hydrolase 13 family
CFK41_RS07120	COG0714	Associated with various cellular activities
CFK41_RS07155	COG0482	sulfurtransferase activity
CFK41_RS07165	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CFK41_RS07175	COG0514	ATP-dependent DNA helicase (RecQ)
CFK41_RS07200	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFK41_RS07205	COG0154	amidase activity
CFK41_RS07210	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFK41_RS07215	COG0076	glutamate decarboxylase activity
CFK41_RS07220	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CFK41_RS07230	COG0129	dihydroxy-acid dehydratase activity
CFK41_RS07240	COG0440	acetolactate synthase activity
CFK41_RS07245	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CFK41_RS07250	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFK41_RS07255	COG0473	3-isopropylmalate dehydrogenase activity
CFK41_RS07260	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CFK41_RS07265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFK41_RS07320	COG0179	Fumarylacetoacetate (FAA) hydrolase
CFK41_RS07325	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFK41_RS07350	COG1414	Transcriptional regulator
CFK41_RS07355	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CFK41_RS07360	COG0066	3-isopropylmalate dehydratase activity
CFK41_RS07365	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CFK41_RS07385	COG1181	Belongs to the D-alanine--D-alanine ligase family
CFK41_RS07395	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CFK41_RS07400	COG1064	alcohol dehydrogenase
CFK41_RS07410	COG3340	Belongs to the peptidase S51 family
CFK41_RS07415	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CFK41_RS07425	COG0742	ribosomal rna small subunit methyltransferase
CFK41_RS07460	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CFK41_RS07465	COG1399	metal-binding, possibly nucleic acid-binding protein
CFK41_RS07470	COG0571	ribonuclease III activity
CFK41_RS07475	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CFK41_RS07495	COG1132	(ABC) transporter
CFK41_RS07500	COG4988	ABC transporter
CFK41_RS07505	COG1294	oxidase, subunit
CFK41_RS07510	COG1271	oxidase subunit
CFK41_RS07515	COG1530	ribonuclease E activity
CFK41_RS07520	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CFK41_RS07525	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CFK41_RS07530	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CFK41_RS07535	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CFK41_RS07540	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CFK41_RS07550	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CFK41_RS07560	COG0799	negative regulation of ribosome biogenesis
CFK41_RS07595	COG0596	Alpha beta hydrolase
CFK41_RS07620	COG2855	membrane
CFK41_RS07645	COG3135	benzoate transporter
CFK41_RS07665	COG0601	transmembrane transport
CFK41_RS07670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFK41_RS07675	COG4172	Belongs to the ABC transporter superfamily
CFK41_RS07695	COG0514	ATP-dependent DNA helicase (RecQ)
CFK41_RS07710	COG1621	beta-fructofuranosidase activity
CFK41_RS07720	COG0395	ABC-type sugar transport system, permease component
CFK41_RS07725	COG4209	transmembrane transport
CFK41_RS07730	COG1609	Transcriptional regulator
CFK41_RS07735	COG2197	response regulator
CFK41_RS07740	COG4585	Histidine kinase
CFK41_RS07765	COG3214	Protein conserved in bacteria
CFK41_RS07785	COG4868	Belongs to the UPF0371 family
CFK41_RS07800	COG3833	ABC-type maltose transport systems, permease component
CFK41_RS07820	COG5578	integral membrane protein
CFK41_RS07825	COG0395	ABC-type sugar transport system, permease component
CFK41_RS07830	COG4209	transmembrane transport
CFK41_RS07835	COG1653	transport
CFK41_RS07845	COG1609	Transcriptional regulator
CFK41_RS07850	COG1609	Transcriptional regulator
CFK41_RS07865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFK41_RS07870	COG1120	ATPase activity
CFK41_RS07885	COG0601	transmembrane transport
CFK41_RS07895	COG0444	Belongs to the ABC transporter superfamily
CFK41_RS07915	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CFK41_RS07925	COG0025	NhaP-type Na H and K H
CFK41_RS07930	COG1263	PTS System
CFK41_RS07930	COG2190	(PTS) system
CFK41_RS07930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFK41_RS07950	COG3104	oligopeptide transport
CFK41_RS07965	COG0519	Catalyzes the synthesis of GMP from XMP
CFK41_RS07970	COG2873	o-acetylhomoserine
CFK41_RS07975	COG2072	flavoprotein involved in K transport
CFK41_RS07990	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFK41_RS08010	COG3594	Acyltransferase
CFK41_RS08025	COG1435	thymidine kinase activity
CFK41_RS08035	COG1082	Xylose isomerase domain protein TIM barrel
CFK41_RS08040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFK41_RS08045	COG0318	PFAM AMP-dependent synthetase and ligase
CFK41_RS08050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFK41_RS08060	COG1555	photosystem II stabilization
CFK41_RS08075	COG0268	Binds directly to 16S ribosomal RNA
CFK41_RS08105	COG2186	Transcriptional regulator
CFK41_RS08110	COG0481	GTPase activity
CFK41_RS08140	COG1420	regulation of RNA biosynthetic process
CFK41_RS08145	COG0484	heat shock protein binding
CFK41_RS08155	COG4555	ABC transporter
CFK41_RS08170	COG0431	NADPH-dependent FMN reductase
CFK41_RS08175	COG0537	adenosine 5'-monophosphoramidase activity
CFK41_RS08185	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CFK41_RS08195	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CFK41_RS08200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFK41_RS08220	COG4106	trans-aconitate 2-methyltransferase activity
CFK41_RS08230	COG1381	Involved in DNA repair and RecF pathway recombination
CFK41_RS08240	COG0477	Major facilitator Superfamily
CFK41_RS08250	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CFK41_RS08265	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFK41_RS08270	COG1121	(ABC) transporter
CFK41_RS08280	COG0423	glycine-tRNA ligase activity
CFK41_RS08295	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CFK41_RS08300	COG0358	DNA primase activity
CFK41_RS08310	COG4585	Histidine kinase
CFK41_RS08315	COG2197	response regulator
CFK41_RS08330	COG4585	Histidine kinase
CFK41_RS08335	COG2197	response regulator
CFK41_RS08380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFK41_RS08385	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFK41_RS08395	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CFK41_RS08425	COG0822	iron-sulfur transferase activity
CFK41_RS08430	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CFK41_RS08435	COG3022	response to hydroperoxide
CFK41_RS08460	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CFK41_RS08475	COG0174	glutamine synthetase
CFK41_RS08480	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CFK41_RS08495	COG0174	glutamine synthetase
CFK41_RS08510	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CFK41_RS08515	COG0321	lipoyl(octanoyl) transferase activity
CFK41_RS08525	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFK41_RS08530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFK41_RS08535	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CFK41_RS08550	COG0167	dihydroorotate dehydrogenase activity
CFK41_RS08560	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CFK41_RS08565	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CFK41_RS08570	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CFK41_RS08580	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFK41_RS08595	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CFK41_RS08620	COG1968	undecaprenyl-diphosphatase activity
CFK41_RS08625	COG0215	cysteine-tRNA ligase activity
CFK41_RS08645	COG1222	aaa ATPase
CFK41_RS08650	COG4122	O-methyltransferase activity
CFK41_RS08660	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CFK41_RS08675	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CFK41_RS08680	COG0471	metal ion transport
CFK41_RS08685	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CFK41_RS08695	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CFK41_RS08705	COG0140	phosphoribosyl-ATP diphosphatase activity
CFK41_RS08710	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CFK41_RS08730	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CFK41_RS08735	COG0805	protein transport
CFK41_RS08745	COG4581	dead DEAH box helicase
CFK41_RS08760	COG1216	Glycosyl transferase, family 2
CFK41_RS08775	COG0584	glycerophosphoryl diester phosphodiesterase
CFK41_RS08805	COG3830	Belongs to the UPF0237 family
CFK41_RS08805	COG0560	Phosphoserine phosphatase
CFK41_RS08815	COG0297	glycogen (starch) synthase activity
CFK41_RS08830	COG1119	ATPase activity
CFK41_RS08865	COG1063	alcohol dehydrogenase
CFK41_RS08890	COG0587	DNA-directed DNA polymerase activity
CFK41_RS08900	COG2409	Drug exporters of the RND superfamily
CFK41_RS08905	COG1309	transcriptional regulator
CFK41_RS08920	COG2814	Major facilitator Superfamily
CFK41_RS08955	COG0673	inositol 2-dehydrogenase activity
CFK41_RS08990	COG1716	ATPase activity
CFK41_RS09015	COG0697	spore germination
CFK41_RS09020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFK41_RS09025	COG0697	spore germination
CFK41_RS09060	COG1131	(ABC) transporter
CFK41_RS09085	COG1012	belongs to the aldehyde dehydrogenase family
CFK41_RS09090	COG0006	proline dipeptidase activity
CFK41_RS09095	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CFK41_RS09105	COG2409	Drug exporters of the RND superfamily
CFK41_RS09115	COG2197	response regulator
CFK41_RS09130	COG1175	transmembrane transport
CFK41_RS09160	COG1160	GTP binding
CFK41_RS09185	COG0109	protoheme IX farnesyltransferase activity
CFK41_RS09195	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CFK41_RS09205	COG0363	glucosamine-6-phosphate deaminase activity
CFK41_RS09210	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CFK41_RS09215	COG0149	triose-phosphate isomerase activity
CFK41_RS09220	COG0126	phosphoglycerate kinase activity
CFK41_RS09225	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CFK41_RS09230	COG1481	regulation of sporulation
CFK41_RS09240	COG1660	Displays ATPase and GTPase activities
CFK41_RS09245	COG0322	excinuclease ABC activity
CFK41_RS09255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFK41_RS09290	COG0556	nucleotide-excision repair
CFK41_RS09295	COG0237	dephospho-CoA kinase activity
CFK41_RS09300	COG2860	membrane
CFK41_RS09310	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CFK41_RS09320	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CFK41_RS09340	COG0539	negative regulation of cytoplasmic translation
CFK41_RS09395	COG1028	Short-chain dehydrogenase reductase Sdr
CFK41_RS09410	COG1335	isochorismatase
CFK41_RS09420	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CFK41_RS09430	COG0469	pyruvate kinase activity
CFK41_RS09440	COG0067	glutamate synthase
CFK41_RS09440	COG0069	glutamate synthase activity
CFK41_RS09440	COG0070	glutamate synthase
CFK41_RS09445	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CFK41_RS09460	COG0134	indole-3-glycerol-phosphate synthase activity
CFK41_RS09485	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CFK41_RS09490	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CFK41_RS09500	COG1758	RNA polymerase activity
CFK41_RS09505	COG0194	GDP metabolic process
CFK41_RS09515	COG0284	orotidine-5'-phosphate decarboxylase activity
CFK41_RS09520	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CFK41_RS09525	COG0505	Belongs to the CarA family
CFK41_RS09535	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CFK41_RS09540	COG0540	Belongs to the ATCase OTCase family
CFK41_RS09545	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CFK41_RS09550	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CFK41_RS09555	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CFK41_RS09565	COG0488	(ABC) transporter
CFK41_RS09580	COG0396	ATPase activity
CFK41_RS09605	COG0435	Glutathione S-transferase
CFK41_RS09625	COG0024	Methionine aminopeptidase
CFK41_RS09630	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CFK41_RS09645	COG4585	Histidine kinase
CFK41_RS09650	COG2197	response regulator
CFK41_RS09660	COG2130	NADP-dependent
CFK41_RS09665	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CFK41_RS09670	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CFK41_RS09685	COG0756	dUTP diphosphatase activity
CFK41_RS09720	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFK41_RS09730	COG0676	glucose-6-phosphate 1-epimerase activity
CFK41_RS09740	COG1408	metallophosphoesterase
CFK41_RS09750	COG0187	DNA topoisomerase II activity
CFK41_RS09760	COG0456	acetyltransferase
CFK41_RS09765	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFK41_RS09775	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CFK41_RS09785	COG0142	geranyltranstransferase activity
CFK41_RS09795	COG2815	serine threonine protein kinase
CFK41_RS09795	COG0515	serine threonine protein kinase
CFK41_RS09800	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CFK41_RS09820	COG1940	carbohydrate kinase activity
CFK41_RS09840	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CFK41_RS09845	COG1845	cytochrome c oxidase, subunit III
CFK41_RS09850	COG2010	Cytochrome c
CFK41_RS09855	COG0723	plastoquinol--plastocyanin reductase activity
CFK41_RS09860	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CFK41_RS09875	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFK41_RS09880	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CFK41_RS09905	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CFK41_RS09915	COG3118	belongs to the thioredoxin family
CFK41_RS09920	COG0124	histidyl-tRNA synthetase
CFK41_RS09925	COG1196	nuclear chromosome segregation
CFK41_RS09935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CFK41_RS09940	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CFK41_RS09950	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CFK41_RS09960	COG2255	four-way junction helicase activity
CFK41_RS09965	COG0632	four-way junction helicase activity
CFK41_RS09970	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CFK41_RS09975	COG0217	transcriptional regulatory protein
CFK41_RS09990	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CFK41_RS09995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CFK41_RS10060	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFK41_RS10070	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CFK41_RS10075	COG0494	nUDIX hydrolase
CFK41_RS10080	COG0504	CTP synthase activity
CFK41_RS10110	COG0497	DNA recombination
CFK41_RS10115	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CFK41_RS10125	COG0647	UMP catabolic process
CFK41_RS10150	COG2226	methyltransferase
CFK41_RS10155	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CFK41_RS10165	COG2252	PERMEase
CFK41_RS10170	COG0363	glucosamine-6-phosphate deaminase activity
CFK41_RS10175	COG1252	NADH dehydrogenase
CFK41_RS10195	COG0148	phosphopyruvate hydratase activity
CFK41_RS10210	COG0193	aminoacyl-tRNA hydrolase activity
CFK41_RS10215	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CFK41_RS10220	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CFK41_RS10225	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CFK41_RS10235	COG1309	transcriptional regulator
CFK41_RS10245	COG0488	(ABC) transporter
CFK41_RS10255	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CFK41_RS10260	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CFK41_RS10265	COG0084	hydrolase, TatD family'
CFK41_RS10295	COG1854	S-ribosylhomocysteine lyase activity
CFK41_RS10325	COG0024	Methionine aminopeptidase
CFK41_RS10335	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CFK41_RS10345	COG0483	inositol monophosphate 1-phosphatase activity
CFK41_RS10365	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CFK41_RS10390	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CFK41_RS10405	COG0395	ABC-type sugar transport system, permease component
CFK41_RS10410	COG4209	transmembrane transport
CFK41_RS10425	COG0579	oxidoreductase
CFK41_RS10430	COG0247	lactate metabolic process
CFK41_RS10440	COG1556	Lactate utilization protein
CFK41_RS10445	COG2017	converts alpha-aldose to the beta-anomer
CFK41_RS10460	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CFK41_RS10465	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CFK41_RS10490	COG0302	gtp cyclohydrolase
CFK41_RS10490	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CFK41_RS10495	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CFK41_RS10500	COG0302	gtp cyclohydrolase
CFK41_RS10505	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFK41_RS10510	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CFK41_RS10515	COG0037	tRNA processing
CFK41_RS10520	COG2027	D-alanyl-D-alanine carboxypeptidase
CFK41_RS10525	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CFK41_RS10535	COG0242	peptide deformylase activity
CFK41_RS10540	COG3842	ATPase activity
CFK41_RS10550	COG2364	Membrane
CFK41_RS10555	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFK41_RS10560	COG0215	cysteine-tRNA ligase activity
CFK41_RS10580	COG2197	response regulator
CFK41_RS10590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFK41_RS10605	COG1902	pentaerythritol trinitrate reductase activity
CFK41_RS10610	COG4221	oxidoreductase activity
CFK41_RS10620	COG1760	l-serine dehydratase
CFK41_RS10625	COG0513	Belongs to the DEAD box helicase family
CFK41_RS10630	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CFK41_RS10640	COG1175	transmembrane transport
CFK41_RS10645	COG0395	ABC-type sugar transport system, permease component
CFK41_RS10660	COG0495	leucyl-tRNA aminoacylation
CFK41_RS10670	COG0542	response to heat
CFK41_RS10685	COG0154	amidase activity
CFK41_RS10705	COG0009	L-threonylcarbamoyladenylate synthase
CFK41_RS10715	COG0813	purine-nucleoside phosphorylase activity
CFK41_RS10725	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CFK41_RS10740	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CFK41_RS10740	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CFK41_RS10745	COG0509	glycine decarboxylation via glycine cleavage system
CFK41_RS10750	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFK41_RS10775	COG1045	serine acetyltransferase
CFK41_RS10790	COG0180	Tryptophanyl-tRNA synthetase
CFK41_RS10810	COG3833	ABC-type maltose transport systems, permease component
CFK41_RS10815	COG0366	Alpha amylase catalytic
CFK41_RS10830	COG1881	PFAM PEBP family protein
CFK41_RS10835	COG0438	transferase activity, transferring glycosyl groups
CFK41_RS10850	COG0789	Transcriptional regulator
CFK41_RS10855	COG0484	heat shock protein binding
CFK41_RS10860	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CFK41_RS10865	COG0443	Heat shock 70 kDa protein
CFK41_RS10870	COG2315	Protein conserved in bacteria
CFK41_RS10925	COG2079	MmgE PrpD family protein
CFK41_RS10930	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CFK41_RS10940	COG2186	Transcriptional regulator
CFK41_RS10950	COG0129	dihydroxy-acid dehydratase activity
CFK41_RS11015	COG0438	transferase activity, transferring glycosyl groups
CFK41_RS11020	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CFK41_RS11050	COG4721	ABC-type cobalt transport system, permease component
CFK41_RS11055	COG1122	ATPase activity
CFK41_RS11070	COG2267	carboxylic ester hydrolase activity
CFK41_RS11080	COG0698	ribose 5-phosphate isomerase
CFK41_RS11085	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CFK41_RS11095	COG1132	(ABC) transporter
CFK41_RS11105	COG0515	serine threonine protein kinase
CFK41_RS11110	COG2197	response regulator
CFK41_RS11115	COG4585	Histidine kinase
CFK41_RS11130	COG1132	(ABC) transporter
CFK41_RS11140	COG0668	transmembrane transport
CFK41_RS11155	COG1946	Acyl-CoA thioesterase
CFK41_RS11185	COG3480	Lon protease (S16) C-terminal proteolytic domain
CFK41_RS11240	COG1309	transcriptional regulator
CFK41_RS11255	COG0513	Belongs to the DEAD box helicase family
CFK41_RS11260	COG0613	PHP domain protein
CFK41_RS11265	COG0006	proline dipeptidase activity
CFK41_RS11270	COG2239	Acts as a magnesium transporter
CFK41_RS11305	COG1611	Belongs to the LOG family
CFK41_RS11310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFK41_RS11330	COG2171	N-acyltransferase activity
CFK41_RS11370	COG1217	gtp-binding protein TYPA
CFK41_RS11380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFK41_RS11395	COG0166	Belongs to the GPI family
CFK41_RS11400	COG0477	Major facilitator Superfamily
CFK41_RS11405	COG2268	Band 7 protein
CFK41_RS11425	COG0587	DNA-directed DNA polymerase activity
CFK41_RS11465	COG1799	cell septum assembly
CFK41_RS11475	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CFK41_RS11480	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CFK41_RS11485	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CFK41_RS11490	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CFK41_RS11500	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CFK41_RS11505	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CFK41_RS11515	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CFK41_RS11520	COG0768	penicillin binding
CFK41_RS11530	COG0275	rRNA processing
CFK41_RS11535	COG2001	Belongs to the MraZ family
CFK41_RS11565	COG1278	Cold shock
CFK41_RS11580	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CFK41_RS11585	COG1388	LysM domain
CFK41_RS11590	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CFK41_RS11600	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CFK41_RS11610	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CFK41_RS11615	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CFK41_RS11625	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CFK41_RS11635	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CFK41_RS11650	COG1058	Belongs to the CinA family
CFK41_RS11650	COG1546	Belongs to the CinA family
CFK41_RS11660	COG1674	ftsk spoiiie
CFK41_RS11665	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CFK41_RS11670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFK41_RS11675	COG0367	asparagine synthase
CFK41_RS11680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFK41_RS11700	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CFK41_RS11705	COG0612	Peptidase, M16
CFK41_RS11710	COG1185	polyribonucleotide nucleotidyltransferase activity
CFK41_RS11715	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CFK41_RS11725	COG1376	ErfK ybiS ycfS ynhG family protein
CFK41_RS11730	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CFK41_RS11735	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CFK41_RS11745	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CFK41_RS11745	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CFK41_RS11760	COG0779	Required for maturation of 30S ribosomal subunits
CFK41_RS11770	COG0442	prolyl-tRNA aminoacylation
CFK41_RS11785	COG2264	protein methyltransferase activity
CFK41_RS11795	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CFK41_RS11800	COG0750	zinc metalloprotease
CFK41_RS11805	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CFK41_RS11820	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CFK41_RS11825	COG0575	Belongs to the CDS family
CFK41_RS11830	COG0233	cytoplasmic translational termination
CFK41_RS11835	COG0528	UMP kinase activity
CFK41_RS11840	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CFK41_RS11845	COG0052	Belongs to the universal ribosomal protein uS2 family
CFK41_RS11855	COG4974	Belongs to the 'phage' integrase family
CFK41_RS11880	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CFK41_RS11885	COG0681	Belongs to the peptidase S26 family
CFK41_RS11890	COG0681	Belongs to the peptidase S26 family
CFK41_RS11895	COG0335	large ribosomal subunit rRNA binding
CFK41_RS11900	COG0336	Belongs to the RNA methyltransferase TrmD family
CFK41_RS11905	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CFK41_RS11915	COG1837	Belongs to the UPF0109 family
CFK41_RS11920	COG0228	four-way junction DNA binding
CFK41_RS11945	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CFK41_RS11970	COG0105	UTP biosynthetic process
CFK41_RS11980	COG0285	dihydrofolate synthase activity
CFK41_RS12000	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CFK41_RS12020	COG1132	(ABC) transporter
CFK41_RS12055	COG4555	ABC transporter
CFK41_RS12065	COG0095	Lipoate-protein ligase
CFK41_RS12075	COG0525	valine-tRNA ligase activity
CFK41_RS12095	COG1921	L-seryl-tRNASec selenium transferase activity
CFK41_RS12115	COG0437	4 iron, 4 sulfur cluster binding
CFK41_RS12120	COG3383	formate dehydrogenase (NAD+) activity
CFK41_RS12120	COG0243	molybdopterin cofactor binding
CFK41_RS12125	COG0243	molybdopterin cofactor binding
CFK41_RS12125	COG3383	formate dehydrogenase (NAD+) activity
CFK41_RS12135	COG1605	Chorismate mutase
CFK41_RS12135	COG0287	Prephenate dehydrogenase
CFK41_RS12140	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CFK41_RS12145	COG0740	serine-type endopeptidase activity
CFK41_RS12150	COG0740	serine-type endopeptidase activity
CFK41_RS12155	COG1388	LysM domain
CFK41_RS12155	COG0791	NLP P60 protein
CFK41_RS12155	COG3103	Sh3 type 3 domain protein
CFK41_RS12165	COG0544	peptidyl-prolyl cis-trans isomerase activity
CFK41_RS12185	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFK41_RS12190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFK41_RS12195	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CFK41_RS12205	COG1136	(ABC) transporter
CFK41_RS12250	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CFK41_RS12255	COG1316	TRANSCRIPTIONal
CFK41_RS12270	COG5002	protein histidine kinase activity
CFK41_RS12275	COG0745	RESPONSE REGULATOR receiver
CFK41_RS12290	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CFK41_RS12300	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CFK41_RS12300	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CFK41_RS12310	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CFK41_RS12315	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CFK41_RS12330	COG1316	TRANSCRIPTIONal
CFK41_RS12340	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CFK41_RS12345	COG2226	methyltransferase
CFK41_RS12350	COG0561	phosphatase activity
CFK41_RS12360	COG1388	LysM domain
CFK41_RS12360	COG0791	NLP P60 protein
CFK41_RS12375	COG0045	succinate-CoA ligase (ADP-forming) activity
CFK41_RS12430	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CFK41_RS12445	COG3142	Participates in the control of copper homeostasis
CFK41_RS12455	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CFK41_RS12470	COG1490	D-aminoacyl-tRNA deacylase activity
CFK41_RS12480	COG0588	phosphoglycerate mutase activity
CFK41_RS12490	COG0433	COG0433 Predicted ATPase
CFK41_RS12505	COG0477	Major facilitator Superfamily
CFK41_RS12515	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CFK41_RS12515	COG0519	Catalyzes the synthesis of GMP from XMP
CFK41_RS12535	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CFK41_RS12565	COG0516	GMP reductase activity
CFK41_RS12605	COG0564	pseudouridine synthase activity
CFK41_RS12615	COG0459	protein refolding
CFK41_RS12620	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CFK41_RS12640	COG0521	Mo-molybdopterin cofactor biosynthetic process
CFK41_RS12640	COG0315	cyclic pyranopterin monophosphate synthase activity
CFK41_RS12645	COG0315	cyclic pyranopterin monophosphate synthase activity
CFK41_RS12655	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CFK41_RS12700	COG0604	alcohol dehydrogenase
CFK41_RS12700	COG1028	Short-chain dehydrogenase reductase Sdr
CFK41_RS12700	COG3321	synthase
CFK41_RS12720	COG0714	Associated with various cellular activities
CFK41_RS12735	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFK41_RS12765	COG0747	negative chemotaxis
CFK41_RS12770	COG0601	transmembrane transport
CFK41_RS12775	COG0444	Belongs to the ABC transporter superfamily
CFK41_RS12785	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFK41_RS12790	COG1940	carbohydrate kinase activity
CFK41_RS12795	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CFK41_RS12815	COG1404	Belongs to the peptidase S8 family
CFK41_RS12835	COG0596	Alpha beta hydrolase
CFK41_RS12840	COG1505	serine-type exopeptidase activity
CFK41_RS12855	COG0351	phosphomethylpyrimidine kinase
CFK41_RS12870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFK41_RS12885	COG2814	Major facilitator Superfamily
CFK41_RS12895	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CFK41_RS12915	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CFK41_RS12925	COG1061	Type III restriction enzyme res subunit
CFK41_RS12930	COG5416	Lipopolysaccharide assembly protein A domain
CFK41_RS12935	COG0745	RESPONSE REGULATOR receiver
CFK41_RS12950	COG2311	Membrane
CFK41_RS12965	COG0328	RNA-DNA hybrid ribonuclease activity
CFK41_RS12985	COG3250	beta-galactosidase activity
CFK41_RS12995	COG0513	Belongs to the DEAD box helicase family
CFK41_RS13005	COG0318	PFAM AMP-dependent synthetase and ligase
CFK41_RS13010	COG0640	Transcriptional regulator
CFK41_RS13015	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CFK41_RS13025	COG0277	FAD linked oxidase domain protein
CFK41_RS13030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFK41_RS13035	COG4166	transmembrane transport
CFK41_RS13045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFK41_RS13060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFK41_RS13065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFK41_RS13080	COG4720	Psort location CytoplasmicMembrane, score
CFK41_RS13090	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CFK41_RS13110	COG0459	protein refolding
CFK41_RS13125	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CFK41_RS13145	COG0515	serine threonine protein kinase
CFK41_RS13145	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFK41_RS13175	COG1764	response to oxidative stress
CFK41_RS13200	COG4209	transmembrane transport
CFK41_RS13205	COG0395	ABC-type sugar transport system, permease component
CFK41_RS13215	COG1940	carbohydrate kinase activity
CFK41_RS13215	COG1846	Transcriptional regulator
CFK41_RS13265	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CFK41_RS13285	COG0667	Aldo Keto reductase
CFK41_RS13290	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CFK41_RS13295	COG1126	abc transporter atp-binding protein
CFK41_RS13300	COG0765	amino acid transport
CFK41_RS13305	COG0765	amino acid transport
CFK41_RS13335	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CFK41_RS13350	COG1063	alcohol dehydrogenase
CFK41_RS13370	COG1268	BioY protein
CFK41_RS13380	COG3408	Glycogen debranching enzyme
CFK41_RS13385	COG1278	Cold shock
CFK41_RS13410	COG1396	sequence-specific DNA binding
CFK41_RS13415	COG0740	serine-type endopeptidase activity
CFK41_RS13420	COG0740	serine-type endopeptidase activity
CFK41_RS13425	COG2213	PTS system mannitol-specific
CFK41_RS13425	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFK41_RS13430	COG0246	Mannitol dehydrogenase
CFK41_RS13440	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CFK41_RS13455	COG0604	alcohol dehydrogenase
CFK41_RS13460	COG0604	alcohol dehydrogenase
CFK41_RS13470	COG0561	phosphatase activity
CFK41_RS13480	COG1597	lipid kinase activity
CFK41_RS13490	COG0077	Prephenate dehydratase
CFK41_RS13535	COG0456	acetyltransferase
CFK41_RS13540	COG2066	Belongs to the glutaminase family
CFK41_RS13550	COG1988	membrane-bound metal-dependent
CFK41_RS13555	COG1051	belongs to the nudix hydrolase family
CFK41_RS13585	COG1120	ATPase activity
CFK41_RS13610	COG0657	acetylesterase activity
CFK41_RS13620	COG3304	Inner membrane component domain
CFK41_RS13625	COG0018	arginyl-trna synthetase
CFK41_RS13635	COG0657	acetylesterase activity
CFK41_RS13640	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CFK41_RS13650	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFK41_RS13670	COG2084	Dehydrogenase
CFK41_RS13715	COG1132	(ABC) transporter
CFK41_RS13725	COG2197	response regulator
CFK41_RS13730	COG4585	Histidine kinase
CFK41_RS13740	COG1131	(ABC) transporter
CFK41_RS13770	COG3642	lipopolysaccharide core region biosynthetic process
CFK41_RS13810	COG1335	isochorismatase
CFK41_RS13815	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFK41_RS13815	COG1902	pentaerythritol trinitrate reductase activity
CFK41_RS13830	COG0386	Belongs to the glutathione peroxidase family
CFK41_RS13855	COG1074	ATP-dependent DNA helicase activity
CFK41_RS13860	COG1072	(Pantothenic acid kinase))
CFK41_RS13870	COG0656	L-ascorbic acid biosynthetic process
CFK41_RS13880	COG2271	Major facilitator Superfamily
CFK41_RS13900	COG0829	nickel cation binding
CFK41_RS13905	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CFK41_RS13925	COG0831	urea catabolic process
CFK41_RS13965	COG0395	ABC-type sugar transport system, permease component
CFK41_RS14000	COG3876	Protein conserved in bacteria
CFK41_RS14020	COG1609	Transcriptional regulator
CFK41_RS14050	COG4585	Histidine kinase
CFK41_RS14060	COG2814	Major facilitator Superfamily
CFK41_RS14090	COG0598	Magnesium transport protein CorA
CFK41_RS14105	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CFK41_RS14110	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CFK41_RS14115	COG3237	CsbD-like
CFK41_RS14125	COG1028	Short-chain dehydrogenase reductase Sdr
CFK41_RS14135	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFK41_RS14145	COG0783	Belongs to the Dps family
CFK41_RS14155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFK41_RS14160	COG4948	Mandelate Racemase Muconate Lactonizing
CFK41_RS14165	COG0395	ABC-type sugar transport system, permease component
CFK41_RS14185	COG1802	Transcriptional regulator
CFK41_RS14200	COG1175	transmembrane transport
CFK41_RS14205	COG0395	ABC-type sugar transport system, permease component
CFK41_RS14225	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFK41_RS14230	COG0395	ABC-type sugar transport system, permease component
CFK41_RS14235	COG1175	transmembrane transport
CFK41_RS14250	COG2084	Dehydrogenase
CFK41_RS14260	COG3622	Belongs to the hyi family
CFK41_RS14275	COG1653	transport
CFK41_RS14290	COG1609	Transcriptional regulator
CFK41_RS14350	COG1609	Transcriptional regulator
CFK41_RS14355	COG4209	transmembrane transport
CFK41_RS14360	COG0395	ABC-type sugar transport system, permease component
CFK41_RS14380	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CFK41_RS14440	COG2814	Major facilitator Superfamily
CFK41_RS14455	COG3395	kinase activity
CFK41_RS14460	COG0235	Class ii aldolase
CFK41_RS14465	COG1349	DNA-binding transcription factor activity
CFK41_RS14500	COG0673	inositol 2-dehydrogenase activity
CFK41_RS14515	COG0395	ABC-type sugar transport system, permease component
CFK41_RS14520	COG3842	ATPase activity
CFK41_RS14530	COG1028	Short-chain dehydrogenase reductase Sdr
CFK41_RS14540	COG1802	Transcriptional regulator
CFK41_RS14545	COG2271	Major facilitator Superfamily
CFK41_RS14550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFK41_RS14555	COG4948	Mandelate Racemase Muconate Lactonizing
CFK41_RS14590	COG0251	oxidation-reduction process
CFK41_RS14595	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CFK41_RS14600	COG0477	Major facilitator Superfamily
CFK41_RS14610	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFK41_RS14625	COG2066	Belongs to the glutaminase family
CFK41_RS14655	COG3534	alpha-L-arabinofuranosidase
CFK41_RS14660	COG3119	arylsulfatase activity
CFK41_RS14670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFK41_RS14680	COG1653	transport
CFK41_RS14685	COG1175	transmembrane transport
CFK41_RS14690	COG0395	ABC-type sugar transport system, permease component
CFK41_RS14700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFK41_RS14705	COG1609	Transcriptional regulator
CFK41_RS14760	COG2272	Belongs to the type-B carboxylesterase lipase family
CFK41_RS14765	COG1486	melibiose metabolic process
CFK41_RS14775	COG3386	PFAM SMP-30 Gluconolaconase
CFK41_RS14790	COG0425	Belongs to the sulfur carrier protein TusA family
CFK41_RS14795	COG2391	methyltransferase activity
CFK41_RS14815	COG2814	Major facilitator Superfamily
CFK41_RS14830	COG0667	Aldo Keto reductase
CFK41_RS14835	COG4989	oxidoreductase activity
CFK41_RS14850	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CFK41_RS14880	COG2264	protein methyltransferase activity
CFK41_RS14885	COG2814	Major facilitator Superfamily
CFK41_RS14895	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CFK41_RS14905	COG0702	epimerase
CFK41_RS14945	COG1309	transcriptional regulator
CFK41_RS14955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFK41_RS14965	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CFK41_RS14970	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CFK41_RS14990	COG2249	NAD(P)H dehydrogenase (quinone) activity
CFK41_RS14995	COG0823	Involved in the tonB-independent uptake of proteins
CFK41_RS15045	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CFK41_RS15050	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CFK41_RS15055	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CFK41_RS15060	COG0254	rRNA binding
CFK41_RS15070	COG0254	rRNA binding
CFK41_RS15075	COG0254	rRNA binding
CFK41_RS15095	COG3119	arylsulfatase activity
CFK41_RS15105	COG4209	transmembrane transport
CFK41_RS15110	COG0395	ABC-type sugar transport system, permease component
CFK41_RS15125	COG1132	(ABC) transporter
CFK41_RS15135	COG0395	ABC-type sugar transport system, permease component
CFK41_RS15140	COG1175	transmembrane transport
CFK41_RS15165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFK41_RS15170	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CFK41_RS15175	COG3387	PFAM Glycoside hydrolase 15-related
CFK41_RS15185	COG1966	Carbon starvation protein
CFK41_RS15200	COG4948	Mandelate Racemase Muconate Lactonizing
CFK41_RS15215	COG1609	Transcriptional regulator
CFK41_RS15220	COG1653	transport
CFK41_RS15225	COG1175	transmembrane transport
CFK41_RS15230	COG0395	ABC-type sugar transport system, permease component
CFK41_RS15240	COG0673	inositol 2-dehydrogenase activity
CFK41_RS15255	COG3775	system Galactitol-specific IIC component
CFK41_RS15260	COG3414	Phosphotransferase system galactitol-specific IIB component
CFK41_RS15265	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFK41_RS15270	COG0022	dehydrogenase e1 component
CFK41_RS15270	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFK41_RS15275	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CFK41_RS15295	COG3732	PTS system glucitol sorbitol-specific
CFK41_RS15300	COG3730	PTS system glucitol sorbitol-specific
CFK41_RS15305	COG0656	L-ascorbic acid biosynthetic process
CFK41_RS15330	COG2390	Transcriptional regulator
CFK41_RS15350	COG1104	cysteine desulfurase activity
CFK41_RS15360	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CFK41_RS15365	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CFK41_RS15375	COG0477	Major facilitator Superfamily
CFK41_RS15380	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFK41_RS15385	COG3739	integral membrane protein
CFK41_RS15405	COG0385	Bile acid
CFK41_RS15420	COG0789	Transcriptional regulator
CFK41_RS15440	COG1643	Atp-dependent helicase
CFK41_RS15455	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CFK41_RS15470	COG0483	inositol monophosphate 1-phosphatase activity
CFK41_RS15500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFK41_RS15505	COG1309	transcriptional regulator
CFK41_RS15515	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFK41_RS15550	COG1028	Short-chain dehydrogenase reductase Sdr
CFK41_RS15555	COG1464	Belongs to the NlpA lipoprotein family
CFK41_RS15560	COG2011	ABC-type metal ion transport system permease component
CFK41_RS15565	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CFK41_RS15580	COG2197	response regulator
CFK41_RS15590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFK41_RS15595	COG1116	anion transmembrane transporter activity
CFK41_RS15600	COG0626	cystathionine gamma-synthase activity
CFK41_RS15605	COG0590	tRNA wobble adenosine to inosine editing
CFK41_RS15610	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CFK41_RS15615	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CFK41_RS15620	COG0745	RESPONSE REGULATOR receiver
CFK41_RS15635	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CFK41_RS15665	COG2807	transmembrane transport
CFK41_RS15670	COG2233	PERMEase
CFK41_RS15675	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CFK41_RS15695	COG0305	Participates in initiation and elongation during chromosome replication
CFK41_RS15720	COG0076	glutamate decarboxylase activity
CFK41_RS15745	COG1132	(ABC) transporter
CFK41_RS15765	COG5002	protein histidine kinase activity
CFK41_RS15770	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFK41_RS15785	COG1063	alcohol dehydrogenase
CFK41_RS15795	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CFK41_RS15865	COG0477	Major facilitator Superfamily
CFK41_RS15875	COG1652	LysM domain
CFK41_RS15895	COG0477	Major facilitator Superfamily
CFK41_RS15905	COG1012	belongs to the aldehyde dehydrogenase family
CFK41_RS15915	COG1482	cell wall glycoprotein biosynthetic process
CFK41_RS15925	COG0028	Belongs to the TPP enzyme family
CFK41_RS15930	COG1253	flavin adenine dinucleotide binding
CFK41_RS15945	COG0577	efflux transmembrane transporter activity
CFK41_RS15945	COG1136	(ABC) transporter
CFK41_RS15950	COG0577	efflux transmembrane transporter activity
CFK41_RS15965	COG0395	ABC-type sugar transport system, permease component
CFK41_RS15970	COG4209	transmembrane transport
CFK41_RS15975	COG1609	Transcriptional regulator
CFK41_RS16005	COG2197	response regulator
CFK41_RS16015	COG1595	DNA-templated transcription, initiation
CFK41_RS16030	COG0667	Aldo Keto reductase
CFK41_RS16055	COG0456	acetyltransferase
CFK41_RS16055	COG0454	-acetyltransferase
CFK41_RS16065	COG0659	secondary active sulfate transmembrane transporter activity
CFK41_RS16095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFK41_RS16100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFK41_RS16110	COG0583	DNA-binding transcription factor activity
CFK41_RS16140	COG1132	(ABC) transporter
CFK41_RS16145	COG1132	(ABC) transporter
CFK41_RS16190	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFK41_RS16195	COG1511	domain protein
CFK41_RS16205	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CFK41_RS16215	COG2514	catechol 2,3-dioxygenase activity
CFK41_RS16220	COG1473	amidohydrolase
CFK41_RS16235	COG0673	inositol 2-dehydrogenase activity
CFK41_RS16245	COG4989	oxidoreductase activity
CFK41_RS16260	COG0673	inositol 2-dehydrogenase activity
CFK41_RS16280	COG0395	ABC-type sugar transport system, permease component
CFK41_RS16285	COG4209	transmembrane transport
CFK41_RS16295	COG1472	Belongs to the glycosyl hydrolase 3 family
CFK41_RS16300	COG1501	Belongs to the glycosyl hydrolase 31 family
CFK41_RS16310	COG1472	Belongs to the glycosyl hydrolase 3 family
CFK41_RS16315	COG0395	ABC-type sugar transport system, permease component
CFK41_RS16320	COG4209	transmembrane transport
CFK41_RS16325	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CFK41_RS16350	COG1175	transmembrane transport
CFK41_RS16355	COG0395	ABC-type sugar transport system, permease component
CFK41_RS16370	COG1070	Carbohydrate kinase
CFK41_RS16375	COG2115	Belongs to the xylose isomerase family
CFK41_RS16390	COG1609	Transcriptional regulator
CFK41_RS16395	COG3458	cephalosporin-C deacetylase activity
CFK41_RS16410	COG0395	ABC-type sugar transport system, permease component
CFK41_RS16415	COG4209	transmembrane transport
CFK41_RS16425	COG0395	ABC-type sugar transport system, permease component
CFK41_RS16430	COG4209	transmembrane transport
CFK41_RS16450	COG1472	Belongs to the glycosyl hydrolase 3 family
CFK41_RS16460	COG1175	transmembrane transport
CFK41_RS16470	COG0673	inositol 2-dehydrogenase activity
CFK41_RS16480	COG0673	inositol 2-dehydrogenase activity
CFK41_RS16485	COG0673	inositol 2-dehydrogenase activity
CFK41_RS16490	COG2985	domain, Protein
CFK41_RS16490	COG0569	domain protein
CFK41_RS16505	COG3250	beta-galactosidase activity
CFK41_RS16515	COG1028	Short-chain dehydrogenase reductase Sdr
CFK41_RS16530	COG2239	Acts as a magnesium transporter
CFK41_RS16535	COG0246	Mannitol dehydrogenase
CFK41_RS16540	COG1063	alcohol dehydrogenase
CFK41_RS16555	COG1846	Transcriptional regulator
CFK41_RS16560	COG2814	Major facilitator Superfamily
CFK41_RS16565	COG0405	Gamma-glutamyltransferase
CFK41_RS16570	COG4948	Mandelate Racemase Muconate Lactonizing
CFK41_RS16575	COG0477	Major facilitator Superfamily
CFK41_RS16595	COG2814	Major facilitator Superfamily
CFK41_RS16600	COG2814	Major facilitator Superfamily
CFK41_RS16610	COG2318	DinB family
CFK41_RS16630	COG2376	Dihydroxyacetone kinase
CFK41_RS16640	COG0406	alpha-ribazole phosphatase activity
CFK41_RS16645	COG3119	arylsulfatase activity
CFK41_RS16650	COG0667	Aldo Keto reductase
CFK41_RS16675	COG1648	precorrin-2 dehydrogenase activity
CFK41_RS16675	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CFK41_RS16680	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFK41_RS16680	COG2146	nitrite reductase [NAD(P)H] activity
CFK41_RS16685	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFK41_RS16700	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CFK41_RS16710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFK41_RS16725	COG0326	Molecular chaperone. Has ATPase activity
CFK41_RS16770	COG1028	Short-chain dehydrogenase reductase Sdr
CFK41_RS16785	COG0789	Transcriptional regulator
CFK41_RS16845	COG3693	PFAM glycoside hydrolase, family 10
CFK41_RS16855	COG0395	ABC-type sugar transport system, permease component
CFK41_RS16860	COG1175	transmembrane transport
CFK41_RS16870	COG1349	DNA-binding transcription factor activity
CFK41_RS16875	COG1486	melibiose metabolic process
CFK41_RS16880	COG0656	L-ascorbic acid biosynthetic process
CFK41_RS16900	COG2188	Transcriptional regulator
CFK41_RS16905	COG0673	inositol 2-dehydrogenase activity
CFK41_RS16910	COG3718	enzyme involved in inositol metabolism
CFK41_RS16930	COG2814	Major facilitator Superfamily
CFK41_RS16935	COG3962	Belongs to the TPP enzyme family
CFK41_RS16945	COG1082	Xylose isomerase domain protein TIM barrel
CFK41_RS16950	COG1082	Xylose isomerase domain protein TIM barrel
CFK41_RS16955	COG0673	inositol 2-dehydrogenase activity
CFK41_RS16965	COG0747	negative chemotaxis
CFK41_RS16970	COG0601	transmembrane transport
CFK41_RS16990	COG2186	Transcriptional regulator
CFK41_RS17010	COG4948	Mandelate Racemase Muconate Lactonizing
CFK41_RS17015	COG0179	Fumarylacetoacetate (FAA) hydrolase
CFK41_RS17020	COG0738	Major facilitator superfamily
CFK41_RS17025	COG0129	dihydroxy-acid dehydratase activity
CFK41_RS17040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFK41_RS17055	COG0179	Fumarylacetoacetate (FAA) hydrolase
CFK41_RS17060	COG4948	Mandelate Racemase Muconate Lactonizing
CFK41_RS17070	COG2271	Major facilitator Superfamily
CFK41_RS17075	COG1028	Short-chain dehydrogenase reductase Sdr
CFK41_RS17085	COG2223	nitrite transmembrane transporter activity
CFK41_RS17090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFK41_RS17095	COG1304	FMN binding
CFK41_RS17100	COG2084	Dehydrogenase
CFK41_RS17110	COG2610	gluconate transmembrane transporter activity
CFK41_RS17115	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFK41_RS17120	COG1028	Short-chain dehydrogenase reductase Sdr
CFK41_RS17130	COG2186	Transcriptional regulator
CFK41_RS17135	COG1082	Xylose isomerase domain protein TIM barrel
CFK41_RS17140	COG2084	Dehydrogenase
CFK41_RS17145	COG2610	gluconate transmembrane transporter activity
CFK41_RS17150	COG2376	Dihydroxyacetone kinase
CFK41_RS17155	COG0698	ribose 5-phosphate isomerase
CFK41_RS17165	COG0149	triose-phosphate isomerase activity
CFK41_RS17185	COG0673	inositol 2-dehydrogenase activity
CFK41_RS17190	COG0673	inositol 2-dehydrogenase activity
CFK41_RS17200	COG3958	Transketolase
CFK41_RS17205	COG3959	Transketolase, thiamine diphosphate binding domain
CFK41_RS17215	COG1028	Short-chain dehydrogenase reductase Sdr
CFK41_RS17230	COG2084	Dehydrogenase
CFK41_RS17235	COG2211	Major facilitator Superfamily
CFK41_RS17245	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CFK41_RS17250	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CFK41_RS17275	COG2197	response regulator
CFK41_RS17280	COG2203	Gaf domain
CFK41_RS17280	COG4585	Histidine kinase
CFK41_RS17285	COG0577	efflux transmembrane transporter activity
CFK41_RS17290	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CFK41_RS17300	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CFK41_RS17305	COG0789	Transcriptional regulator
CFK41_RS17330	COG1522	sequence-specific DNA binding
CFK41_RS17390	COG1595	DNA-templated transcription, initiation
CFK41_RS17405	COG0415	Belongs to the DNA photolyase family
CFK41_RS17415	COG0456	acetyltransferase
CFK41_RS17415	COG0454	-acetyltransferase
CFK41_RS17420	COG0442	prolyl-tRNA aminoacylation
CFK41_RS17430	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFK41_RS17435	COG0187	DNA topoisomerase II activity
CFK41_RS17440	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CFK41_RS17445	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFK41_RS17445	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFK41_RS17450	COG0307	riboflavin synthase, alpha
CFK41_RS17460	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CFK41_RS17465	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CFK41_RS17470	COG0592	DNA-directed DNA polymerase activity
CFK41_RS17475	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CFK41_RS17480	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CFK41_RS17485	COG0594	ribonuclease P activity
CFK41_RS17495	COG0706	membrane insertase activity
CFK41_RS17505	COG0357	Ribosomal RNA small subunit methyltransferase G
CFK41_RS17510	COG1192	Involved in chromosome partitioning
CFK41_RS17525	COG0492	ferredoxin-NADP+ reductase activity
CFK41_RS17550	COG0617	tRNA 3'-terminal CCA addition
CFK41_RS17555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CFK41_RS17565	COG0360	Binds together with S18 to 16S ribosomal RNA
CFK41_RS17570	COG0629	single-stranded DNA binding
CFK41_RS17575	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CFK41_RS17580	COG0359	binds to the 23S rRNA
CFK41_RS17585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFK41_RS17595	COG0222	ribosome binding
CFK41_RS17620	COG2267	carboxylic ester hydrolase activity
CFK41_RS17635	COG1063	alcohol dehydrogenase
CFK41_RS17640	COG0673	inositol 2-dehydrogenase activity
CFK41_RS17650	COG1940	carbohydrate kinase activity
CFK41_RS17655	COG0397	Uncharacterized ACR, YdiU/UPF0061 family