CFK41_RS02365 459f9672200c96f930222996dee592b6 322 Pfam PF13377 Periplasmic binding protein-like domain 157 318 1.6E-34 T 28-03-2018 CFK41_RS02365 459f9672200c96f930222996dee592b6 322 Gene3D G3DSA:3.40.50.2300 162 299 3.7E-37 T 28-03-2018 CFK41_RS02365 459f9672200c96f930222996dee592b6 322 Gene3D G3DSA:1.10.260.40 1 41 3.8E-12 T 28-03-2018 CFK41_RS02365 459f9672200c96f930222996dee592b6 322 SMART SM00354 1 57 7.2E-8 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS02365 459f9672200c96f930222996dee592b6 322 Gene3D G3DSA:3.40.50.2300 42 161 5.2E-23 T 28-03-2018 CFK41_RS02365 459f9672200c96f930222996dee592b6 322 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 34 5.9E-8 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS02365 459f9672200c96f930222996dee592b6 322 SUPERFAMILY SSF53822 48 320 2.17E-48 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS02365 459f9672200c96f930222996dee592b6 322 SUPERFAMILY SSF47413 1 45 7.31E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS05495 0d58a255808b1d465478abf26951846b 318 SUPERFAMILY SSF53613 1 311 1.42E-54 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS05495 0d58a255808b1d465478abf26951846b 318 Pfam PF00294 pfkB family carbohydrate kinase 24 305 1.4E-32 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CFK41_RS05495 0d58a255808b1d465478abf26951846b 318 Gene3D G3DSA:2.20.150.10 9 42 1.8E-12 T 28-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain CFK41_RS05495 0d58a255808b1d465478abf26951846b 318 PIRSF PIRSF000535 1 314 2.4E-57 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CFK41_RS05495 0d58a255808b1d465478abf26951846b 318 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 310 6.8E-78 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CFK41_RS05495 0d58a255808b1d465478abf26951846b 318 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 258 271 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CFK41_RS05495 0d58a255808b1d465478abf26951846b 318 Gene3D G3DSA:3.40.1190.20 43 316 2.7E-37 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS05495 0d58a255808b1d465478abf26951846b 318 PRINTS PR00990 Ribokinase signature 32 51 9.4E-5 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CFK41_RS05495 0d58a255808b1d465478abf26951846b 318 PRINTS PR00990 Ribokinase signature 229 240 9.4E-5 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CFK41_RS11515 d06889a04d04d8df3286a96ed402bd9c 529 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 27 512 30.081 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CFK41_RS11515 d06889a04d04d8df3286a96ed402bd9c 529 Pfam PF02875 Mur ligase family, glutamate ligase domain 358 442 1.2E-21 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CFK41_RS11515 d06889a04d04d8df3286a96ed402bd9c 529 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 42 512 5.2E-130 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CFK41_RS11515 d06889a04d04d8df3286a96ed402bd9c 529 Gene3D G3DSA:3.40.1390.10 20 121 2.5E-20 T 28-03-2018 CFK41_RS11515 d06889a04d04d8df3286a96ed402bd9c 529 Pfam PF08245 Mur ligase middle domain 132 334 3.6E-42 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CFK41_RS11515 d06889a04d04d8df3286a96ed402bd9c 529 Gene3D G3DSA:3.40.1190.10 123 362 9.8E-53 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CFK41_RS11515 d06889a04d04d8df3286a96ed402bd9c 529 SUPERFAMILY SSF63418 28 122 8.24E-18 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CFK41_RS11515 d06889a04d04d8df3286a96ed402bd9c 529 Gene3D G3DSA:3.90.190.20 365 528 3.3E-40 T 28-03-2018 CFK41_RS11515 d06889a04d04d8df3286a96ed402bd9c 529 SUPERFAMILY SSF53623 123 353 3.21E-62 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CFK41_RS11515 d06889a04d04d8df3286a96ed402bd9c 529 SUPERFAMILY SSF53244 358 513 6.11E-40 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CFK41_RS11515 d06889a04d04d8df3286a96ed402bd9c 529 Pfam PF01225 Mur ligase family, catalytic domain 44 117 1.5E-10 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CFK41_RS15975 e7450e71d463867c030add175242f557 339 Gene3D G3DSA:3.40.50.2300 181 337 4.4E-35 T 28-03-2018 CFK41_RS15975 e7450e71d463867c030add175242f557 339 SUPERFAMILY SSF47413 11 70 6.96E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS15975 e7450e71d463867c030add175242f557 339 SMART SM00354 11 81 3.5E-27 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS15975 e7450e71d463867c030add175242f557 339 SUPERFAMILY SSF53822 72 337 5.3E-43 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS15975 e7450e71d463867c030add175242f557 339 Gene3D G3DSA:3.40.50.2300 64 180 5.0E-14 T 28-03-2018 CFK41_RS15975 e7450e71d463867c030add175242f557 339 Gene3D G3DSA:1.10.10.10 6 25 0.0073 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS15975 e7450e71d463867c030add175242f557 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 13 58 1.3E-16 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS15975 e7450e71d463867c030add175242f557 339 Pfam PF13377 Periplasmic binding protein-like domain 175 334 8.9E-33 T 28-03-2018 CFK41_RS15975 e7450e71d463867c030add175242f557 339 Gene3D G3DSA:1.10.260.40 26 63 2.6E-23 T 28-03-2018 CFK41_RS07055 64c8df9c5fcaca1d612ec1cf7eacf03d 541 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 383 506 4.1E-43 T 28-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07055 64c8df9c5fcaca1d612ec1cf7eacf03d 541 SUPERFAMILY SSF47917 384 511 8.11E-42 T 28-03-2018 CFK41_RS07055 64c8df9c5fcaca1d612ec1cf7eacf03d 541 SUPERFAMILY SSF52540 100 382 3.36E-94 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS07055 64c8df9c5fcaca1d612ec1cf7eacf03d 541 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 30 96 3.9E-15 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CFK41_RS07055 64c8df9c5fcaca1d612ec1cf7eacf03d 541 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 153 376 7.1E-68 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CFK41_RS07055 64c8df9c5fcaca1d612ec1cf7eacf03d 541 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 6 512 3.0E-235 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07055 64c8df9c5fcaca1d612ec1cf7eacf03d 541 SUPERFAMILY SSF50615 27 98 1.1E-22 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CFK41_RS07055 64c8df9c5fcaca1d612ec1cf7eacf03d 541 Gene3D G3DSA:3.40.50.300 87 376 2.9E-107 T 28-03-2018 CFK41_RS07055 64c8df9c5fcaca1d612ec1cf7eacf03d 541 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 367 376 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CFK41_RS07055 64c8df9c5fcaca1d612ec1cf7eacf03d 541 Gene3D G3DSA:2.40.30.20 6 86 1.7E-29 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07055 64c8df9c5fcaca1d612ec1cf7eacf03d 541 Gene3D G3DSA:1.20.150.20 385 511 9.1E-46 T 28-03-2018 CFK41_RS07055 64c8df9c5fcaca1d612ec1cf7eacf03d 541 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 4 512 47.463 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS11665 86b17a2f1426a5e7c0ce8b2c4e1758da 564 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 371 407 4.0E-7 T 28-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CFK41_RS11665 86b17a2f1426a5e7c0ce8b2c4e1758da 564 PIRSF PIRSF004803 15 564 6.8E-205 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CFK41_RS11665 86b17a2f1426a5e7c0ce8b2c4e1758da 564 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 21 561 1.8E-146 T 28-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 CFK41_RS11665 86b17a2f1426a5e7c0ce8b2c4e1758da 564 SUPERFAMILY SSF56281 20 434 4.19E-90 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS11665 86b17a2f1426a5e7c0ce8b2c4e1758da 564 Gene3D G3DSA:3.60.15.10 12 458 2.4E-61 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS11665 86b17a2f1426a5e7c0ce8b2c4e1758da 564 Hamap MF_01491 Ribonuclease J [rnj]. 15 564 39.828 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CFK41_RS11665 86b17a2f1426a5e7c0ce8b2c4e1758da 564 SMART SM00849 32 226 4.0E-21 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS11665 86b17a2f1426a5e7c0ce8b2c4e1758da 564 Pfam PF00753 Metallo-beta-lactamase superfamily 29 175 3.9E-14 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS15760 dfda5e32f04f2b2c7d312c4201bb6b55 228 SUPERFAMILY SSF46894 126 224 4.25E-24 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CFK41_RS15760 dfda5e32f04f2b2c7d312c4201bb6b55 228 Pfam PF00072 Response regulator receiver domain 3 113 1.9E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS15760 dfda5e32f04f2b2c7d312c4201bb6b55 228 Gene3D G3DSA:3.40.50.2300 1 124 7.8E-35 T 28-03-2018 CFK41_RS15760 dfda5e32f04f2b2c7d312c4201bb6b55 228 SMART SM00448 1 112 5.1E-37 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS15760 dfda5e32f04f2b2c7d312c4201bb6b55 228 SMART SM00862 152 223 4.1E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CFK41_RS15760 dfda5e32f04f2b2c7d312c4201bb6b55 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 223 8.1E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CFK41_RS15760 dfda5e32f04f2b2c7d312c4201bb6b55 228 SUPERFAMILY SSF52172 1 117 8.54E-36 T 28-03-2018 IPR011006 CheY-like superfamily CFK41_RS15760 dfda5e32f04f2b2c7d312c4201bb6b55 228 Gene3D G3DSA:1.10.10.10 125 228 4.1E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS06070 28a12fccbc2e2599b05973293dc80fa2 221 SMART SM01133 8 215 3.7E-86 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CFK41_RS06070 28a12fccbc2e2599b05973293dc80fa2 221 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 9 212 2.1E-66 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CFK41_RS06070 28a12fccbc2e2599b05973293dc80fa2 221 Pfam PF01791 DeoC/LacD family aldolase 13 213 2.4E-15 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CFK41_RS06070 28a12fccbc2e2599b05973293dc80fa2 221 PIRSF PIRSF001357 2 220 1.9E-69 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CFK41_RS06070 28a12fccbc2e2599b05973293dc80fa2 221 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 7 217 32.295 T 28-03-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 CFK41_RS06070 28a12fccbc2e2599b05973293dc80fa2 221 Gene3D G3DSA:3.20.20.70 2 217 1.9E-87 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS06070 28a12fccbc2e2599b05973293dc80fa2 221 SUPERFAMILY SSF51569 8 215 8.58E-71 T 28-03-2018 CFK41_RS07035 f9e88e42b2b5be1bbb3eaf5d9265e52e 247 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 11 241 1.1E-37 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07035 f9e88e42b2b5be1bbb3eaf5d9265e52e 247 SUPERFAMILY SSF81336 75 240 1.19E-32 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07035 f9e88e42b2b5be1bbb3eaf5d9265e52e 247 Pfam PF00119 ATP synthase A chain 26 240 1.5E-48 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07035 f9e88e42b2b5be1bbb3eaf5d9265e52e 247 PRINTS PR00123 ATP synthase A subunit signature 81 97 1.8E-17 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07035 f9e88e42b2b5be1bbb3eaf5d9265e52e 247 PRINTS PR00123 ATP synthase A subunit signature 226 241 1.8E-17 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07035 f9e88e42b2b5be1bbb3eaf5d9265e52e 247 PRINTS PR00123 ATP synthase A subunit signature 166 188 1.8E-17 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07035 f9e88e42b2b5be1bbb3eaf5d9265e52e 247 Hamap MF_01393 ATP synthase subunit a [atpB]. 21 246 14.071 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07035 f9e88e42b2b5be1bbb3eaf5d9265e52e 247 Gene3D G3DSA:1.20.120.220 25 247 1.0E-32 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS06825 6bf3bf7467e60429ec96e0979145861b 307 SUPERFAMILY SSF81624 2 149 1.31E-19 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CFK41_RS06825 6bf3bf7467e60429ec96e0979145861b 307 Gene3D G3DSA:1.10.8.50 135 284 6.3E-41 T 28-03-2018 CFK41_RS06825 6bf3bf7467e60429ec96e0979145861b 307 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 140 201 4.6E-10 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CFK41_RS06825 6bf3bf7467e60429ec96e0979145861b 307 SMART SM01232 140 231 4.0E-23 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CFK41_RS06825 6bf3bf7467e60429ec96e0979145861b 307 SMART SM00898 2 119 1.2E-14 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CFK41_RS06825 6bf3bf7467e60429ec96e0979145861b 307 SUPERFAMILY SSF57716 238 283 1.8E-7 T 28-03-2018 CFK41_RS06825 6bf3bf7467e60429ec96e0979145861b 307 Gene3D G3DSA:3.20.190.10 1 134 4.0E-22 T 28-03-2018 CFK41_RS06825 6bf3bf7467e60429ec96e0979145861b 307 SUPERFAMILY SSF46946 139 218 1.68E-15 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CFK41_RS06825 6bf3bf7467e60429ec96e0979145861b 307 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 113 2.0E-10 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CFK41_RS06300 8e4b8ac55b63c201f13fff9156408c1f 284 SUPERFAMILY SSF56112 14 255 2.92E-15 T 28-03-2018 IPR011009 Protein kinase-like domain CFK41_RS06300 8e4b8ac55b63c201f13fff9156408c1f 284 Gene3D G3DSA:1.10.510.10 54 276 7.1E-12 T 28-03-2018 CFK41_RS06300 8e4b8ac55b63c201f13fff9156408c1f 284 Pfam PF01636 Phosphotransferase enzyme family 48 241 2.2E-12 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CFK41_RS12735 263829d742e8dbc61dd396b7e98a7d0b 230 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 60 219 4.1E-52 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CFK41_RS12735 263829d742e8dbc61dd396b7e98a7d0b 230 SUPERFAMILY SSF55068 51 228 3.66E-63 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CFK41_RS12735 263829d742e8dbc61dd396b7e98a7d0b 230 Gene3D G3DSA:3.30.1060.10 47 230 7.4E-66 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CFK41_RS12735 263829d742e8dbc61dd396b7e98a7d0b 230 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 59 225 34.552 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CFK41_RS12735 263829d742e8dbc61dd396b7e98a7d0b 230 Pfam PF01625 Peptide methionine sulfoxide reductase 61 220 2.6E-58 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CFK41_RS15200 a4261656f455ac155ad9485326bd39a1 403 Gene3D G3DSA:3.30.390.10 13 142 5.0E-20 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS15200 a4261656f455ac155ad9485326bd39a1 403 SUPERFAMILY SSF51604 128 370 2.36E-61 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS15200 a4261656f455ac155ad9485326bd39a1 403 Gene3D G3DSA:3.20.20.120 143 369 1.5E-61 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS15200 a4261656f455ac155ad9485326bd39a1 403 SMART SM00922 158 255 2.0E-20 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CFK41_RS15200 a4261656f455ac155ad9485326bd39a1 403 Pfam PF13378 Enolase C-terminal domain-like 161 371 2.9E-45 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS15200 a4261656f455ac155ad9485326bd39a1 403 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 29 140 8.3E-13 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CFK41_RS15200 a4261656f455ac155ad9485326bd39a1 403 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 115 140 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CFK41_RS15200 a4261656f455ac155ad9485326bd39a1 403 SUPERFAMILY SSF54826 20 141 8.2E-21 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS01935 dd1ae7b22b1ae30e77907c021f36c768 546 Pfam PF00209 Sodium:neurotransmitter symporter family 155 501 3.6E-76 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CFK41_RS01935 dd1ae7b22b1ae30e77907c021f36c768 546 Pfam PF00209 Sodium:neurotransmitter symporter family 17 131 1.5E-39 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CFK41_RS01935 dd1ae7b22b1ae30e77907c021f36c768 546 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 271 291 2.3E-30 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CFK41_RS01935 dd1ae7b22b1ae30e77907c021f36c768 546 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 25 46 2.3E-30 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CFK41_RS01935 dd1ae7b22b1ae30e77907c021f36c768 546 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 325 344 2.3E-30 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CFK41_RS01935 dd1ae7b22b1ae30e77907c021f36c768 546 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 444 464 2.3E-30 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CFK41_RS01935 dd1ae7b22b1ae30e77907c021f36c768 546 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 54 73 2.3E-30 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CFK41_RS01935 dd1ae7b22b1ae30e77907c021f36c768 546 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 98 124 2.3E-30 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CFK41_RS01935 dd1ae7b22b1ae30e77907c021f36c768 546 SUPERFAMILY SSF161070 17 504 1.14E-131 T 28-03-2018 CFK41_RS02595 754e778417e3ffa563a9fd155e2f8828 599 Gene3D G3DSA:2.60.120.260 4 188 4.3E-46 T 28-03-2018 IPR008979 Galactose-binding domain-like CFK41_RS02595 754e778417e3ffa563a9fd155e2f8828 599 SUPERFAMILY SSF51445 294 468 1.9E-58 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS02595 754e778417e3ffa563a9fd155e2f8828 599 SUPERFAMILY SSF51445 506 592 1.9E-58 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS02595 754e778417e3ffa563a9fd155e2f8828 599 SUPERFAMILY SSF49303 197 296 2.88E-8 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CFK41_RS02595 754e778417e3ffa563a9fd155e2f8828 599 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 369 464 1.6E-6 T 28-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 CFK41_RS02595 754e778417e3ffa563a9fd155e2f8828 599 Pfam PF00703 Glycosyl hydrolases family 2 191 296 9.2E-7 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CFK41_RS02595 754e778417e3ffa563a9fd155e2f8828 599 SUPERFAMILY SSF49785 11 188 2.55E-48 T 28-03-2018 IPR008979 Galactose-binding domain-like CFK41_RS02595 754e778417e3ffa563a9fd155e2f8828 599 Gene3D G3DSA:3.20.20.80 299 593 1.5E-43 T 28-03-2018 CFK41_RS02595 754e778417e3ffa563a9fd155e2f8828 599 Gene3D G3DSA:2.60.40.10 190 297 5.0E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS02595 754e778417e3ffa563a9fd155e2f8828 599 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 23 188 2.1E-13 T 28-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CFK41_RS01840 32f86e85fde1246a24de9e53a03d1b5f 278 SUPERFAMILY SSF51658 4 267 3.67E-58 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS01840 32f86e85fde1246a24de9e53a03d1b5f 278 Pfam PF01261 Xylose isomerase-like TIM barrel 27 213 8.1E-28 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS01840 32f86e85fde1246a24de9e53a03d1b5f 278 Gene3D G3DSA:3.20.20.150 1 274 6.0E-51 T 28-03-2018 CFK41_RS07505 fe90cc861957f1107e1d6fa83e540d12 357 PIRSF PIRSF000267 2 342 6.6E-100 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CFK41_RS07505 fe90cc861957f1107e1d6fa83e540d12 357 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 7 326 4.6E-97 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CFK41_RS07505 fe90cc861957f1107e1d6fa83e540d12 357 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 4 219 2.0E-56 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CFK41_RS00045 13767f9bf26fffa5730d2d3d1ccc15ff 283 Pfam PF03618 Kinase/pyrophosphorylase 17 273 1.7E-69 T 28-03-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 CFK41_RS00045 13767f9bf26fffa5730d2d3d1ccc15ff 283 Hamap MF_01062 Phosphoenolpyruvate synthase regulatory protein [ppsR]. 14 282 61.734 T 28-03-2018 IPR026530 Phosphoenolpyruvate synthase regulatory protein CFK41_RS17460 40ce264a2cdb492bc9049629b88aaff4 262 Pfam PF05258 Protein of unknown function (DUF721) 149 234 3.5E-24 T 28-03-2018 IPR007922 Protein of unknown function DUF721/UPF0232 CFK41_RS15625 1653032cb7371cd57dc74676df4cd22e 252 SUPERFAMILY SSF81606 7 250 3.66E-8 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CFK41_RS15625 1653032cb7371cd57dc74676df4cd22e 252 Pfam PF13672 Protein phosphatase 2C 13 201 1.1E-9 T 28-03-2018 CFK41_RS15625 1653032cb7371cd57dc74676df4cd22e 252 Gene3D G3DSA:3.60.40.10 1 251 4.4E-9 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CFK41_RS16770 022b5463b6fbbab881eb9a06f55c0437 266 SUPERFAMILY SSF51735 3 261 2.13E-65 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS16770 022b5463b6fbbab881eb9a06f55c0437 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.7E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS16770 022b5463b6fbbab881eb9a06f55c0437 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.7E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS16770 022b5463b6fbbab881eb9a06f55c0437 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.7E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS16770 022b5463b6fbbab881eb9a06f55c0437 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.1E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS16770 022b5463b6fbbab881eb9a06f55c0437 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 1.1E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS16770 022b5463b6fbbab881eb9a06f55c0437 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.1E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS16770 022b5463b6fbbab881eb9a06f55c0437 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.1E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS16770 022b5463b6fbbab881eb9a06f55c0437 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.1E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS16770 022b5463b6fbbab881eb9a06f55c0437 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.1E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS16770 022b5463b6fbbab881eb9a06f55c0437 266 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 261 2.4E-46 T 28-03-2018 CFK41_RS16770 022b5463b6fbbab881eb9a06f55c0437 266 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CFK41_RS16770 022b5463b6fbbab881eb9a06f55c0437 266 Gene3D G3DSA:3.40.50.720 2 265 3.5E-59 T 28-03-2018 CFK41_RS10750 32622708ddbdc39476c4e77faa0649d0 377 Hamap MF_00259 Aminomethyltransferase [gcvT]. 5 376 39.595 T 28-03-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CFK41_RS10750 32622708ddbdc39476c4e77faa0649d0 377 Pfam PF01571 Aminomethyltransferase folate-binding domain 11 271 4.9E-87 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal CFK41_RS10750 32622708ddbdc39476c4e77faa0649d0 377 Gene3D G3DSA:3.30.1360.120 6 137 2.2E-31 T 28-03-2018 CFK41_RS10750 32622708ddbdc39476c4e77faa0649d0 377 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 279 371 8.2E-19 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CFK41_RS10750 32622708ddbdc39476c4e77faa0649d0 377 Gene3D G3DSA:3.30.1360.120 138 249 1.2E-25 T 28-03-2018 CFK41_RS10750 32622708ddbdc39476c4e77faa0649d0 377 SUPERFAMILY SSF101790 294 375 3.27E-22 T 28-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain CFK41_RS10750 32622708ddbdc39476c4e77faa0649d0 377 Gene3D G3DSA:2.40.30.110 294 377 6.3E-23 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CFK41_RS10750 32622708ddbdc39476c4e77faa0649d0 377 SUPERFAMILY SSF103025 5 287 1.73E-84 T 28-03-2018 CFK41_RS10750 32622708ddbdc39476c4e77faa0649d0 377 PIRSF PIRSF006487 1 377 5.2E-86 T 28-03-2018 CFK41_RS10750 32622708ddbdc39476c4e77faa0649d0 377 Gene3D G3DSA:4.10.1250.10 250 290 5.7E-10 T 28-03-2018 CFK41_RS10750 32622708ddbdc39476c4e77faa0649d0 377 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 7 375 5.7E-101 T 28-03-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 CFK41_RS07420 c45c26f6edb8c893800f958f8d58a78a 737 Gene3D G3DSA:3.40.50.300 477 667 8.9E-29 T 28-03-2018 CFK41_RS07420 c45c26f6edb8c893800f958f8d58a78a 737 Pfam PF17191 RecG wedge domain 21 182 2.8E-6 T 28-03-2018 IPR033454 RecG, wedge domain CFK41_RS07420 c45c26f6edb8c893800f958f8d58a78a 737 Pfam PF00271 Helicase conserved C-terminal domain 551 625 8.0E-18 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS07420 c45c26f6edb8c893800f958f8d58a78a 737 SUPERFAMILY SSF52540 403 509 1.55E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS07420 c45c26f6edb8c893800f958f8d58a78a 737 SUPERFAMILY SSF52540 541 633 1.55E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS07420 c45c26f6edb8c893800f958f8d58a78a 737 Gene3D G3DSA:3.40.50.300 256 470 4.8E-33 T 28-03-2018 CFK41_RS07420 c45c26f6edb8c893800f958f8d58a78a 737 SMART SM00487 269 475 8.6E-29 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CFK41_RS07420 c45c26f6edb8c893800f958f8d58a78a 737 Pfam PF00270 DEAD/DEAH box helicase 294 445 6.5E-16 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CFK41_RS07420 c45c26f6edb8c893800f958f8d58a78a 737 SUPERFAMILY SSF52540 192 466 1.38E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS07420 c45c26f6edb8c893800f958f8d58a78a 737 Gene3D G3DSA:2.40.50.140 49 154 5.1E-18 T 28-03-2018 CFK41_RS07420 c45c26f6edb8c893800f958f8d58a78a 737 SMART SM00490 544 626 1.2E-19 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS07420 c45c26f6edb8c893800f958f8d58a78a 737 SUPERFAMILY SSF50249 23 183 7.2E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS03445 880d1d6cff9a567f7a37b0da48dddf63 284 Gene3D G3DSA:1.10.3720.10 2 271 4.0E-37 T 28-03-2018 CFK41_RS03445 880d1d6cff9a567f7a37b0da48dddf63 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 278 1.4E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS03445 880d1d6cff9a567f7a37b0da48dddf63 284 SUPERFAMILY SSF161098 6 284 2.24E-64 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS13035 18254abe41ec3a4c6bcdfdd55e4c83db 545 SUPERFAMILY SSF53850 60 540 2.71E-91 T 28-03-2018 CFK41_RS13035 18254abe41ec3a4c6bcdfdd55e4c83db 545 PIRSF PIRSF002741 11 539 1.1E-61 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CFK41_RS13035 18254abe41ec3a4c6bcdfdd55e4c83db 545 Gene3D G3DSA:3.40.190.10 166 308 3.3E-26 T 28-03-2018 CFK41_RS13035 18254abe41ec3a4c6bcdfdd55e4c83db 545 Gene3D G3DSA:3.90.76.10 58 165 4.0E-25 T 28-03-2018 CFK41_RS13035 18254abe41ec3a4c6bcdfdd55e4c83db 545 Gene3D G3DSA:3.10.105.10 309 511 1.4E-38 T 28-03-2018 CFK41_RS13035 18254abe41ec3a4c6bcdfdd55e4c83db 545 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 85 434 1.5E-65 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CFK41_RS08810 e8986b83c922d83ff33f140d0b7c7f44 413 Gene3D G3DSA:3.90.550.10 6 291 4.0E-58 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS08810 e8986b83c922d83ff33f140d0b7c7f44 413 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 197 207 - T 28-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CFK41_RS08810 e8986b83c922d83ff33f140d0b7c7f44 413 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 97 105 - T 28-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CFK41_RS08810 e8986b83c922d83ff33f140d0b7c7f44 413 Gene3D G3DSA:2.160.10.10 292 413 7.1E-11 T 28-03-2018 CFK41_RS08810 e8986b83c922d83ff33f140d0b7c7f44 413 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 3 411 45.02 T 28-03-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CFK41_RS08810 e8986b83c922d83ff33f140d0b7c7f44 413 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 6 384 4.2E-133 T 28-03-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CFK41_RS08810 e8986b83c922d83ff33f140d0b7c7f44 413 SUPERFAMILY SSF53448 3 281 3.83E-66 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS08810 e8986b83c922d83ff33f140d0b7c7f44 413 SUPERFAMILY SSF53448 348 364 3.83E-66 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS08810 e8986b83c922d83ff33f140d0b7c7f44 413 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 12 31 - T 28-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CFK41_RS08810 e8986b83c922d83ff33f140d0b7c7f44 413 Pfam PF00483 Nucleotidyl transferase 8 277 3.3E-65 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CFK41_RS08810 e8986b83c922d83ff33f140d0b7c7f44 413 SUPERFAMILY SSF51161 299 411 6.38E-17 T 28-03-2018 IPR011004 Trimeric LpxA-like CFK41_RS01520 5638754e8fcc5813ce4761f78f133a0e 119 Gene3D G3DSA:3.30.70.100 3 102 4.0E-24 T 28-03-2018 CFK41_RS01520 5638754e8fcc5813ce4761f78f133a0e 119 SUPERFAMILY SSF54909 7 100 2.63E-21 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CFK41_RS01520 5638754e8fcc5813ce4761f78f133a0e 119 Pfam PF07045 Domain of unknown function (DUF1330) 7 100 4.0E-25 T 28-03-2018 IPR010753 Domain of unknown function DUF1330 CFK41_RS12105 b21b91e2610e36439157b9487f27e88e 339 Gene3D G3DSA:3.30.1330.10 7 173 4.4E-34 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CFK41_RS12105 b21b91e2610e36439157b9487f27e88e 339 Pfam PF02769 AIR synthase related protein, C-terminal domain 180 337 8.7E-14 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CFK41_RS12105 b21b91e2610e36439157b9487f27e88e 339 Pfam PF00586 AIR synthase related protein, N-terminal domain 57 166 7.8E-18 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CFK41_RS12105 b21b91e2610e36439157b9487f27e88e 339 Gene3D G3DSA:3.90.650.10 174 321 1.1E-29 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CFK41_RS12105 b21b91e2610e36439157b9487f27e88e 339 TIGRFAM TIGR00476 selD: selenide, water dikinase 15 318 7.1E-111 T 28-03-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 CFK41_RS12105 b21b91e2610e36439157b9487f27e88e 339 Hamap MF_00625 Selenide, water dikinase [selD]. 13 339 35.128 T 28-03-2018 IPR023061 Selenophosphate synthetase, class I GO:0004756|GO:0005524|GO:0016260 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 CFK41_RS12105 b21b91e2610e36439157b9487f27e88e 339 SUPERFAMILY SSF55326 16 171 4.84E-37 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CFK41_RS12105 b21b91e2610e36439157b9487f27e88e 339 PIRSF PIRSF036407 9 320 1.3E-93 T 28-03-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 CFK41_RS12105 b21b91e2610e36439157b9487f27e88e 339 SUPERFAMILY SSF56042 173 337 1.5E-35 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CFK41_RS11025 9ae3bc6977ad27e05345b2d7b70f1fe4 238 SUPERFAMILY SSF56219 5 238 1.96E-26 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS11025 9ae3bc6977ad27e05345b2d7b70f1fe4 238 Gene3D G3DSA:3.60.10.10 2 238 1.4E-25 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS11025 9ae3bc6977ad27e05345b2d7b70f1fe4 238 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 11 229 9.9E-9 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS07475 c8e0d72cc1af4b3135622f37d779285a 327 SMART SM00898 2 140 2.3E-36 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CFK41_RS07475 c8e0d72cc1af4b3135622f37d779285a 327 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 138 3.6E-27 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CFK41_RS07475 c8e0d72cc1af4b3135622f37d779285a 327 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 170 256 1.2E-17 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CFK41_RS07475 c8e0d72cc1af4b3135622f37d779285a 327 ProSitePatterns PS01242 Zinc finger FPG-type signature. 285 309 - T 28-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 CFK41_RS07475 c8e0d72cc1af4b3135622f37d779285a 327 Pfam PF06827 Zinc finger found in FPG and IleRS 282 309 6.3E-13 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CFK41_RS07475 c8e0d72cc1af4b3135622f37d779285a 327 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 309 3.8E-69 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CFK41_RS07475 c8e0d72cc1af4b3135622f37d779285a 327 Gene3D G3DSA:1.10.8.50 171 319 1.6E-41 T 28-03-2018 CFK41_RS07475 c8e0d72cc1af4b3135622f37d779285a 327 Gene3D G3DSA:3.20.190.10 2 150 1.2E-34 T 28-03-2018 CFK41_RS07475 c8e0d72cc1af4b3135622f37d779285a 327 SUPERFAMILY SSF46946 169 258 1.09E-19 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CFK41_RS07475 c8e0d72cc1af4b3135622f37d779285a 327 SMART SM01232 169 261 1.8E-30 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CFK41_RS07475 c8e0d72cc1af4b3135622f37d779285a 327 SUPERFAMILY SSF57716 261 310 3.56E-17 T 28-03-2018 CFK41_RS07475 c8e0d72cc1af4b3135622f37d779285a 327 SUPERFAMILY SSF81624 2 141 4.06E-26 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CFK41_RS11275 ce08b3cf2d0b49e651971dd3c783bda5 207 Pfam PF06210 Protein of unknown function (DUF1003) 39 143 4.0E-35 T 28-03-2018 IPR010406 Protein of unknown function DUF1003 CFK41_RS13725 a4d5ed667d6cd4eb6581e3559405171c 211 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 205 3.5E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS13725 a4d5ed667d6cd4eb6581e3559405171c 211 SUPERFAMILY SSF46894 140 211 2.31E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CFK41_RS13725 a4d5ed667d6cd4eb6581e3559405171c 211 ProSitePatterns PS00622 LuxR-type HTH domain signature. 165 192 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS13725 a4d5ed667d6cd4eb6581e3559405171c 211 Gene3D G3DSA:1.10.10.10 135 211 1.1E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS13725 a4d5ed667d6cd4eb6581e3559405171c 211 SUPERFAMILY SSF52172 1 140 1.71E-27 T 28-03-2018 IPR011006 CheY-like superfamily CFK41_RS13725 a4d5ed667d6cd4eb6581e3559405171c 211 SMART SM00421 148 205 1.1E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS13725 a4d5ed667d6cd4eb6581e3559405171c 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 1.2E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS13725 a4d5ed667d6cd4eb6581e3559405171c 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 1.2E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS13725 a4d5ed667d6cd4eb6581e3559405171c 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 1.2E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS13725 a4d5ed667d6cd4eb6581e3559405171c 211 SMART SM00448 2 125 3.3E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS13725 a4d5ed667d6cd4eb6581e3559405171c 211 Pfam PF00072 Response regulator receiver domain 5 126 3.4E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS13725 a4d5ed667d6cd4eb6581e3559405171c 211 Gene3D G3DSA:3.40.50.2300 1 134 1.6E-31 T 28-03-2018 CFK41_RS09605 51d9b67927426d554c5b26221a0178b0 349 Pfam PF13409 Glutathione S-transferase, N-terminal domain 52 146 2.2E-10 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CFK41_RS09605 51d9b67927426d554c5b26221a0178b0 349 SUPERFAMILY SSF47616 155 290 4.04E-30 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CFK41_RS09605 51d9b67927426d554c5b26221a0178b0 349 Pfam PF13410 Glutathione S-transferase, C-terminal domain 195 262 3.4E-13 T 28-03-2018 CFK41_RS09605 51d9b67927426d554c5b26221a0178b0 349 Gene3D G3DSA:3.40.30.10 23 176 9.6E-24 T 28-03-2018 CFK41_RS09605 51d9b67927426d554c5b26221a0178b0 349 PIRSF PIRSF015753 2 313 1.2E-104 T 28-03-2018 IPR016639 Glutathione S-transferase (GST) KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 CFK41_RS09605 51d9b67927426d554c5b26221a0178b0 349 Gene3D G3DSA:1.20.1050.10 177 317 3.0E-40 T 28-03-2018 CFK41_RS17290 fdb952574917f99daedc4161155482ec 248 Gene3D G3DSA:3.40.50.300 16 248 4.8E-64 T 28-03-2018 CFK41_RS17290 fdb952574917f99daedc4161155482ec 248 SUPERFAMILY SSF52540 20 246 1.86E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS17290 fdb952574917f99daedc4161155482ec 248 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS17290 fdb952574917f99daedc4161155482ec 248 Pfam PF00005 ABC transporter 47 197 1.5E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS17290 fdb952574917f99daedc4161155482ec 248 SMART SM00382 54 245 1.3E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS13065 5ea949eaa0dee528224ed5d1ea7935e8 334 SUPERFAMILY SSF51679 7 330 2.22E-67 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CFK41_RS13065 5ea949eaa0dee528224ed5d1ea7935e8 334 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 8 331 2.4E-108 T 28-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 CFK41_RS13065 5ea949eaa0dee528224ed5d1ea7935e8 334 Pfam PF00296 Luciferase-like monooxygenase 21 307 1.6E-28 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CFK41_RS13065 5ea949eaa0dee528224ed5d1ea7935e8 334 Gene3D G3DSA:3.20.20.30 4 333 1.7E-64 T 28-03-2018 CFK41_RS10935 be00c76f65efa9c7dcda5a0f33a1a701 386 Gene3D G3DSA:1.10.580.10 17 278 1.3E-79 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CFK41_RS10935 be00c76f65efa9c7dcda5a0f33a1a701 386 SUPERFAMILY SSF48256 8 382 9.55E-118 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CFK41_RS10935 be00c76f65efa9c7dcda5a0f33a1a701 386 PIRSF PIRSF001369 3 385 8.0E-108 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type CFK41_RS10935 be00c76f65efa9c7dcda5a0f33a1a701 386 Gene3D G3DSA:1.10.580.10 315 369 2.0E-10 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CFK41_RS10935 be00c76f65efa9c7dcda5a0f33a1a701 386 Pfam PF00285 Citrate synthase, C-terminal domain 11 371 1.8E-110 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CFK41_RS10935 be00c76f65efa9c7dcda5a0f33a1a701 386 PRINTS PR00143 Citrate synthase signature 265 285 9.5E-36 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CFK41_RS10935 be00c76f65efa9c7dcda5a0f33a1a701 386 PRINTS PR00143 Citrate synthase signature 129 142 9.5E-36 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CFK41_RS10935 be00c76f65efa9c7dcda5a0f33a1a701 386 PRINTS PR00143 Citrate synthase signature 203 231 9.5E-36 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CFK41_RS10935 be00c76f65efa9c7dcda5a0f33a1a701 386 PRINTS PR00143 Citrate synthase signature 322 338 9.5E-36 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CFK41_RS10935 be00c76f65efa9c7dcda5a0f33a1a701 386 PRINTS PR00143 Citrate synthase signature 181 196 9.5E-36 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CFK41_RS10935 be00c76f65efa9c7dcda5a0f33a1a701 386 PRINTS PR00143 Citrate synthase signature 342 356 9.5E-36 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CFK41_RS10935 be00c76f65efa9c7dcda5a0f33a1a701 386 ProSitePatterns PS00480 Citrate synthase signature. 272 284 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CFK41_RS16825 c33c231136eba23290d94f0b54ffab02 218 SUPERFAMILY SSF46689 6 77 1.15E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS16825 c33c231136eba23290d94f0b54ffab02 218 Gene3D G3DSA:1.10.10.60 12 49 4.5E-13 T 28-03-2018 CFK41_RS16825 c33c231136eba23290d94f0b54ffab02 218 Gene3D G3DSA:1.10.10.60 50 69 4.6E-10 T 28-03-2018 CFK41_RS16825 c33c231136eba23290d94f0b54ffab02 218 Pfam PF13305 WHG domain 97 194 1.9E-14 T 28-03-2018 IPR025996 WHG domain CFK41_RS16825 c33c231136eba23290d94f0b54ffab02 218 SUPERFAMILY SSF48498 91 217 2.18E-13 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CFK41_RS16825 c33c231136eba23290d94f0b54ffab02 218 Gene3D G3DSA:1.10.357.10 70 218 4.7E-24 T 28-03-2018 CFK41_RS16825 c33c231136eba23290d94f0b54ffab02 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 2.1E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS02035 a01037b6427f6a8f467e2ea61fc74c32 587 Pfam PF00005 ABC transporter 353 508 3.4E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS02035 a01037b6427f6a8f467e2ea61fc74c32 587 SUPERFAMILY SSF52540 334 580 1.92E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS02035 a01037b6427f6a8f467e2ea61fc74c32 587 Gene3D G3DSA:1.20.1560.10 2 317 2.5E-68 T 28-03-2018 CFK41_RS02035 a01037b6427f6a8f467e2ea61fc74c32 587 ProSitePatterns PS00211 ABC transporters family signature. 482 496 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS02035 a01037b6427f6a8f467e2ea61fc74c32 587 Gene3D G3DSA:3.40.50.300 326 586 1.4E-62 T 28-03-2018 CFK41_RS02035 a01037b6427f6a8f467e2ea61fc74c32 587 SUPERFAMILY SSF90123 7 321 8.11E-69 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS02035 a01037b6427f6a8f467e2ea61fc74c32 587 SMART SM00382 362 556 3.8E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS02035 a01037b6427f6a8f467e2ea61fc74c32 587 Pfam PF00664 ABC transporter transmembrane region 20 288 6.7E-40 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS03660 03310e2b14fc323c4152d28f33c41ecf 442 Pfam PF07690 Major Facilitator Superfamily 26 369 1.5E-32 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS03660 03310e2b14fc323c4152d28f33c41ecf 442 Gene3D G3DSA:1.20.1250.20 10 208 4.1E-23 T 28-03-2018 CFK41_RS03660 03310e2b14fc323c4152d28f33c41ecf 442 SUPERFAMILY SSF103473 7 419 5.62E-50 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS03660 03310e2b14fc323c4152d28f33c41ecf 442 Gene3D G3DSA:1.20.1250.20 210 418 3.2E-16 T 28-03-2018 CFK41_RS15420 34370306d2d09bdaebd79f40415aa00a 222 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 5.8E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS15420 34370306d2d09bdaebd79f40415aa00a 222 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 5.8E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS15420 34370306d2d09bdaebd79f40415aa00a 222 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 5.8E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS15420 34370306d2d09bdaebd79f40415aa00a 222 Pfam PF13411 MerR HTH family regulatory protein 1 67 1.6E-12 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS15420 34370306d2d09bdaebd79f40415aa00a 222 SUPERFAMILY SSF46955 1 85 5.95E-12 T 28-03-2018 IPR009061 Putative DNA-binding domain CFK41_RS15420 34370306d2d09bdaebd79f40415aa00a 222 Gene3D G3DSA:1.10.1660.10 1 193 1.3E-13 T 28-03-2018 CFK41_RS15420 34370306d2d09bdaebd79f40415aa00a 222 SMART SM00422 1 71 3.2E-4 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS12645 e0590a96aff5aaa6474382f43454150b 167 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 2 156 34.73 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CFK41_RS12645 e0590a96aff5aaa6474382f43454150b 167 Pfam PF01967 MoaC family 15 148 2.7E-51 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CFK41_RS12645 e0590a96aff5aaa6474382f43454150b 167 SUPERFAMILY SSF55040 11 153 6.28E-55 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CFK41_RS12645 e0590a96aff5aaa6474382f43454150b 167 Gene3D G3DSA:3.30.70.640 2 156 1.7E-62 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CFK41_RS12645 e0590a96aff5aaa6474382f43454150b 167 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 150 5.0E-62 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CFK41_RS08040 fdb09f7a497a4b96da9708d2ba50609c 343 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 258 343 4.9E-15 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CFK41_RS08040 fdb09f7a497a4b96da9708d2ba50609c 343 Gene3D G3DSA:3.40.47.10 9 194 9.5E-26 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CFK41_RS08040 fdb09f7a497a4b96da9708d2ba50609c 343 Gene3D G3DSA:3.40.47.10 195 343 6.3E-20 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CFK41_RS08040 fdb09f7a497a4b96da9708d2ba50609c 343 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 125 216 1.4E-12 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CFK41_RS08040 fdb09f7a497a4b96da9708d2ba50609c 343 SUPERFAMILY SSF53901 54 343 3.05E-33 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CFK41_RS01135 e1036223bb4a8d745863bcb22f7b8dc8 580 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 35 52 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CFK41_RS01135 e1036223bb4a8d745863bcb22f7b8dc8 580 Pfam PF01266 FAD dependent oxidoreductase 31 358 2.2E-44 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CFK41_RS01135 e1036223bb4a8d745863bcb22f7b8dc8 580 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 30 42 9.1E-30 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CFK41_RS01135 e1036223bb4a8d745863bcb22f7b8dc8 580 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 59 71 9.1E-30 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CFK41_RS01135 e1036223bb4a8d745863bcb22f7b8dc8 580 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 43 53 9.1E-30 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CFK41_RS01135 e1036223bb4a8d745863bcb22f7b8dc8 580 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 383 395 9.1E-30 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CFK41_RS01135 e1036223bb4a8d745863bcb22f7b8dc8 580 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 105 117 9.1E-30 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CFK41_RS01135 e1036223bb4a8d745863bcb22f7b8dc8 580 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 349 355 9.1E-30 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CFK41_RS01135 e1036223bb4a8d745863bcb22f7b8dc8 580 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 416 540 5.0E-30 T 28-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CFK41_RS01135 e1036223bb4a8d745863bcb22f7b8dc8 580 Gene3D G3DSA:3.50.50.60 5 97 5.4E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS01135 e1036223bb4a8d745863bcb22f7b8dc8 580 Gene3D G3DSA:3.30.9.10 217 356 3.9E-35 T 28-03-2018 CFK41_RS01135 e1036223bb4a8d745863bcb22f7b8dc8 580 Gene3D G3DSA:3.30.9.10 109 216 2.6E-13 T 28-03-2018 CFK41_RS01135 e1036223bb4a8d745863bcb22f7b8dc8 580 SUPERFAMILY SSF51905 31 259 2.07E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS01135 e1036223bb4a8d745863bcb22f7b8dc8 580 SUPERFAMILY SSF51905 298 357 2.07E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS01135 e1036223bb4a8d745863bcb22f7b8dc8 580 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 388 398 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CFK41_RS01390 0548c75d2bfdaf6a5dc5867e4c8ac2ae 392 ProDom PD042532 ISOMERASE L-RHAMNOSE METAL-BINDING METABOLISM RHAMNOSE MANGANESE ENZYME KINASE 3D-STRUCTURE RHAA/RHAB 40 236 7.0E-4 T 28-03-2018 CFK41_RS01390 0548c75d2bfdaf6a5dc5867e4c8ac2ae 392 Pfam PF06134 L-rhamnose isomerase (RhaA) 83 362 1.6E-6 T 28-03-2018 IPR009308 Rhamnose isomerase GO:0008740|GO:0019299|GO:0030145 KEGG: 00051+5.3.1.14 CFK41_RS01390 0548c75d2bfdaf6a5dc5867e4c8ac2ae 392 SUPERFAMILY SSF51658 29 363 2.09E-84 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS01390 0548c75d2bfdaf6a5dc5867e4c8ac2ae 392 Gene3D G3DSA:3.20.20.150 6 383 6.1E-100 T 28-03-2018 CFK41_RS01390 0548c75d2bfdaf6a5dc5867e4c8ac2ae 392 TIGRFAM TIGR02635 RhaI_grampos: L-rhamnose isomerase 10 382 3.5E-181 T 28-03-2018 IPR013457 Rhamnose isomerase-related CFK41_RS08795 5dfa6b9d62f5268faa82bd081b8e3ed5 241 SUPERFAMILY SSF51735 9 237 7.43E-78 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS08795 5dfa6b9d62f5268faa82bd081b8e3ed5 241 Gene3D G3DSA:3.40.50.720 47 241 6.5E-66 T 28-03-2018 CFK41_RS08795 5dfa6b9d62f5268faa82bd081b8e3ed5 241 Gene3D G3DSA:3.40.50.720 1 46 3.0E-8 T 28-03-2018 CFK41_RS08795 5dfa6b9d62f5268faa82bd081b8e3ed5 241 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 183 1.5E-8 T 28-03-2018 CFK41_RS08795 5dfa6b9d62f5268faa82bd081b8e3ed5 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 1.2E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS08795 5dfa6b9d62f5268faa82bd081b8e3ed5 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.2E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS08795 5dfa6b9d62f5268faa82bd081b8e3ed5 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 1.2E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS08795 5dfa6b9d62f5268faa82bd081b8e3ed5 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 1.2E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS08795 5dfa6b9d62f5268faa82bd081b8e3ed5 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 1.2E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS08795 5dfa6b9d62f5268faa82bd081b8e3ed5 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 1.2E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS08795 5dfa6b9d62f5268faa82bd081b8e3ed5 241 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 237 2.4E-58 T 28-03-2018 CFK41_RS08795 5dfa6b9d62f5268faa82bd081b8e3ed5 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 6.8E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS08795 5dfa6b9d62f5268faa82bd081b8e3ed5 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 6.8E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS08795 5dfa6b9d62f5268faa82bd081b8e3ed5 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 6.8E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS12365 0b37a96c503916c6d72489cb6400c19c 239 Gene3D G3DSA:1.10.10.10 3 74 3.1E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS12365 0b37a96c503916c6d72489cb6400c19c 239 SUPERFAMILY SSF47979 66 135 4.32E-20 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CFK41_RS12365 0b37a96c503916c6d72489cb6400c19c 239 Gene3D G3DSA:2.30.30.90 131 235 6.8E-13 T 28-03-2018 CFK41_RS12365 0b37a96c503916c6d72489cb6400c19c 239 SMART SM00529 27 126 1.3E-29 T 28-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 CFK41_RS12365 0b37a96c503916c6d72489cb6400c19c 239 Gene3D G3DSA:1.10.60.10 76 130 3.8E-19 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CFK41_RS12365 0b37a96c503916c6d72489cb6400c19c 239 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 66 134 3.8E-22 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CFK41_RS12365 0b37a96c503916c6d72489cb6400c19c 239 SUPERFAMILY SSF46785 6 64 4.75E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS12365 0b37a96c503916c6d72489cb6400c19c 239 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 4 59 5.3E-15 T 28-03-2018 IPR022687 DTXR-type HTH domain GO:0003677 CFK41_RS12365 0b37a96c503916c6d72489cb6400c19c 239 SUPERFAMILY SSF50037 131 235 1.24E-12 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal CFK41_RS01690 6bbac7e1d43fd44513e8ed28049dd9bc 169 SUPERFAMILY SSF55961 16 163 1.19E-35 T 28-03-2018 CFK41_RS01690 6bbac7e1d43fd44513e8ed28049dd9bc 169 Gene3D G3DSA:3.30.530.20 4 168 2.6E-24 T 28-03-2018 IPR023393 START-like domain CFK41_RS01690 6bbac7e1d43fd44513e8ed28049dd9bc 169 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 29 160 2.2E-17 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CFK41_RS10490 a0785f50eca0fd9cd62067904226fc2e 305 SUPERFAMILY SSF55083 140 286 2.75E-41 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CFK41_RS10490 a0785f50eca0fd9cd62067904226fc2e 305 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 141 268 6.0E-30 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CFK41_RS10490 a0785f50eca0fd9cd62067904226fc2e 305 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 225 236 - T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CFK41_RS10490 a0785f50eca0fd9cd62067904226fc2e 305 Gene3D G3DSA:3.30.1130.10 5 138 1.4E-29 T 28-03-2018 CFK41_RS10490 a0785f50eca0fd9cd62067904226fc2e 305 Gene3D G3DSA:3.30.70.560 139 294 9.8E-46 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CFK41_RS10490 a0785f50eca0fd9cd62067904226fc2e 305 Pfam PF02152 Dihydroneopterin aldolase 18 132 5.4E-29 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CFK41_RS10490 a0785f50eca0fd9cd62067904226fc2e 305 SUPERFAMILY SSF55620 16 133 7.23E-29 T 28-03-2018 CFK41_RS10490 a0785f50eca0fd9cd62067904226fc2e 305 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 140 267 4.0E-34 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CFK41_RS10490 a0785f50eca0fd9cd62067904226fc2e 305 SMART SM00905 18 133 1.5E-39 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CFK41_RS10490 a0785f50eca0fd9cd62067904226fc2e 305 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 16 133 3.7E-30 T 28-03-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CFK41_RS10490 a0785f50eca0fd9cd62067904226fc2e 305 TIGRFAM TIGR00526 folB_dom: FolB domain 16 134 4.4E-22 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CFK41_RS11165 0acf57476fb25edb76be5944cf8532fc 854 PIRSF PIRSF000460 1 803 1.5E-248 T 28-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CFK41_RS11165 0acf57476fb25edb76be5944cf8532fc 854 SUPERFAMILY SSF53756 9 749 3.49E-184 T 28-03-2018 CFK41_RS11165 0acf57476fb25edb76be5944cf8532fc 854 Pfam PF00343 Carbohydrate phosphorylase 129 175 3.1E-5 T 28-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CFK41_RS11165 0acf57476fb25edb76be5944cf8532fc 854 Pfam PF00343 Carbohydrate phosphorylase 280 635 1.1E-19 T 28-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CFK41_RS11165 0acf57476fb25edb76be5944cf8532fc 854 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 112 717 4.3E-237 T 28-03-2018 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CFK41_RS11165 0acf57476fb25edb76be5944cf8532fc 854 Pfam PF11897 Protein of unknown function (DUF3417) 13 125 2.3E-32 T 28-03-2018 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CFK41_RS11165 0acf57476fb25edb76be5944cf8532fc 854 Gene3D G3DSA:3.40.50.2000 430 751 1.5E-72 T 28-03-2018 CFK41_RS11165 0acf57476fb25edb76be5944cf8532fc 854 Gene3D G3DSA:3.40.50.2000 115 429 7.5E-75 T 28-03-2018 CFK41_RS11165 0acf57476fb25edb76be5944cf8532fc 854 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 607 619 - T 28-03-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CFK41_RS14530 edd50e243b0407ec4aa3f72dff935a09 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 95 106 2.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS14530 edd50e243b0407ec4aa3f72dff935a09 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 2.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS14530 edd50e243b0407ec4aa3f72dff935a09 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 2.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS14530 edd50e243b0407ec4aa3f72dff935a09 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 27 257 5.1E-55 T 28-03-2018 CFK41_RS14530 edd50e243b0407ec4aa3f72dff935a09 259 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 19 199 1.6E-4 T 28-03-2018 CFK41_RS14530 edd50e243b0407ec4aa3f72dff935a09 259 Gene3D G3DSA:3.40.50.720 1 259 1.5E-67 T 28-03-2018 CFK41_RS14530 edd50e243b0407ec4aa3f72dff935a09 259 SUPERFAMILY SSF51735 19 257 1.22E-73 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS14530 edd50e243b0407ec4aa3f72dff935a09 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 1.7E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS14530 edd50e243b0407ec4aa3f72dff935a09 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 1.7E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS14530 edd50e243b0407ec4aa3f72dff935a09 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 20 37 1.7E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS14530 edd50e243b0407ec4aa3f72dff935a09 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 1.7E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS14530 edd50e243b0407ec4aa3f72dff935a09 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 95 106 1.7E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS07760 a68665fb52acf2c6ee01bc72d32cc354 294 SUPERFAMILY SSF56219 29 289 4.19E-35 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS07760 a68665fb52acf2c6ee01bc72d32cc354 294 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 34 284 6.6E-10 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS07760 a68665fb52acf2c6ee01bc72d32cc354 294 Gene3D G3DSA:3.60.10.10 25 294 5.0E-34 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS04900 90b33ffedefca40ba856e9d05cfad04e 448 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 445 42.007 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS04900 90b33ffedefca40ba856e9d05cfad04e 448 SUPERFAMILY SSF53738 258 365 3.34E-28 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS04900 90b33ffedefca40ba856e9d05cfad04e 448 Gene3D G3DSA:3.40.120.10 157 269 1.1E-30 T 28-03-2018 CFK41_RS04900 90b33ffedefca40ba856e9d05cfad04e 448 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 137 1.8E-37 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS04900 90b33ffedefca40ba856e9d05cfad04e 448 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 374 439 1.5E-15 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS04900 90b33ffedefca40ba856e9d05cfad04e 448 SUPERFAMILY SSF53738 157 256 4.71E-25 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS04900 90b33ffedefca40ba856e9d05cfad04e 448 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 98 107 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS04900 90b33ffedefca40ba856e9d05cfad04e 448 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 258 368 3.5E-31 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS04900 90b33ffedefca40ba856e9d05cfad04e 448 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 158 254 4.1E-18 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS04900 90b33ffedefca40ba856e9d05cfad04e 448 SUPERFAMILY SSF55957 361 446 8.89E-22 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS04900 90b33ffedefca40ba856e9d05cfad04e 448 Gene3D G3DSA:3.40.120.10 270 374 2.5E-30 T 28-03-2018 CFK41_RS04900 90b33ffedefca40ba856e9d05cfad04e 448 Gene3D G3DSA:3.40.120.10 2 148 2.6E-43 T 28-03-2018 CFK41_RS04900 90b33ffedefca40ba856e9d05cfad04e 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 174 193 7.4E-12 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS04900 90b33ffedefca40ba856e9d05cfad04e 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 234 249 7.4E-12 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS04900 90b33ffedefca40ba856e9d05cfad04e 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 97 111 7.4E-12 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS04900 90b33ffedefca40ba856e9d05cfad04e 448 SUPERFAMILY SSF53738 4 181 4.32E-43 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS04900 90b33ffedefca40ba856e9d05cfad04e 448 Gene3D G3DSA:3.30.310.50 375 447 7.5E-20 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS04900 90b33ffedefca40ba856e9d05cfad04e 448 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 443 2.8E-159 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS06545 2dadb6bf7c1aedbdffe7bf46c84964df 485 SMART SM00919 238 460 4.3E-108 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CFK41_RS06545 2dadb6bf7c1aedbdffe7bf46c84964df 485 Pfam PF03949 Malic enzyme, NAD binding domain 240 459 2.5E-25 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CFK41_RS06545 2dadb6bf7c1aedbdffe7bf46c84964df 485 Gene3D G3DSA:3.30.70.260 3 92 3.6E-6 T 28-03-2018 CFK41_RS06545 2dadb6bf7c1aedbdffe7bf46c84964df 485 Gene3D G3DSA:3.40.50.10380 93 235 2.9E-39 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CFK41_RS06545 2dadb6bf7c1aedbdffe7bf46c84964df 485 SUPERFAMILY SSF53223 87 236 2.09E-56 T 28-03-2018 CFK41_RS06545 2dadb6bf7c1aedbdffe7bf46c84964df 485 Pfam PF00390 Malic enzyme, N-terminal domain 104 226 1.1E-29 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CFK41_RS06545 2dadb6bf7c1aedbdffe7bf46c84964df 485 PIRSF PIRSF000106 67 478 8.3E-83 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CFK41_RS06545 2dadb6bf7c1aedbdffe7bf46c84964df 485 Gene3D G3DSA:3.40.50.720 236 480 5.4E-70 T 28-03-2018 CFK41_RS06545 2dadb6bf7c1aedbdffe7bf46c84964df 485 SMART SM01274 93 226 4.2E-82 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CFK41_RS06545 2dadb6bf7c1aedbdffe7bf46c84964df 485 SUPERFAMILY SSF51735 238 463 2.8E-68 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS07270 d5b7e91b765c211e0d1798917c6620f5 179 Gene3D G3DSA:3.30.70.260 5 86 4.9E-14 T 28-03-2018 CFK41_RS07270 d5b7e91b765c211e0d1798917c6620f5 179 SUPERFAMILY SSF55021 94 174 7.08E-8 T 28-03-2018 CFK41_RS07270 d5b7e91b765c211e0d1798917c6620f5 179 SUPERFAMILY SSF55021 8 80 2.91E-13 T 28-03-2018 CFK41_RS07270 d5b7e91b765c211e0d1798917c6620f5 179 Gene3D G3DSA:3.30.70.260 90 178 3.4E-15 T 28-03-2018 CFK41_RS07270 d5b7e91b765c211e0d1798917c6620f5 179 Pfam PF13740 ACT domain 11 81 5.6E-16 T 28-03-2018 CFK41_RS07270 d5b7e91b765c211e0d1798917c6620f5 179 PIRSF PIRSF028103 7 179 1.1E-37 T 28-03-2018 IPR016867 Glycine cleavage system transcriptional repressor GO:0006355 CFK41_RS15675 e8fa52522489c754e8f5fe560eb43dc9 528 Pfam PF00474 Sodium:solute symporter family 37 446 1.5E-90 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CFK41_RS11545 fd23388e2a8e3c936f12d7233b426d6e 135 Gene3D G3DSA:1.20.1250.20 23 95 5.9E-4 T 28-03-2018 CFK41_RS11545 fd23388e2a8e3c936f12d7233b426d6e 135 Pfam PF11239 Protein of unknown function (DUF3040) 1 80 1.0E-24 T 28-03-2018 IPR021401 Protein of unknown function DUF3040 CFK41_RS15315 ef819efb0fc82824ab74458cecd7219d 159 SMART SM00422 41 112 1.6E-19 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS15315 ef819efb0fc82824ab74458cecd7219d 159 Pfam PF00376 MerR family regulatory protein 42 81 1.2E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS15315 ef819efb0fc82824ab74458cecd7219d 159 Gene3D G3DSA:1.10.1660.10 50 99 1.8E-19 T 28-03-2018 CFK41_RS15315 ef819efb0fc82824ab74458cecd7219d 159 Pfam PF09278 MerR, DNA binding 86 147 2.3E-9 T 28-03-2018 IPR015358 Transcription regulator MerR, DNA binding CFK41_RS15315 ef819efb0fc82824ab74458cecd7219d 159 Gene3D G3DSA:1.10.10.10 8 49 0.0043 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS15315 ef819efb0fc82824ab74458cecd7219d 159 ProSitePatterns PS00552 MerR-type HTH domain signature. 44 66 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS15315 ef819efb0fc82824ab74458cecd7219d 159 Gene3D G3DSA:1.10.1660.10 100 159 2.6E-8 T 28-03-2018 CFK41_RS15315 ef819efb0fc82824ab74458cecd7219d 159 SUPERFAMILY SSF46955 41 152 8.06E-25 T 28-03-2018 IPR009061 Putative DNA-binding domain CFK41_RS11010 e6c72c672f09e5f55d8a822ae8cbf68d 199 SUPERFAMILY SSF53335 10 194 9.11E-24 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS11010 e6c72c672f09e5f55d8a822ae8cbf68d 199 Pfam PF13649 Methyltransferase domain 41 133 4.4E-9 T 28-03-2018 CFK41_RS11010 e6c72c672f09e5f55d8a822ae8cbf68d 199 Gene3D G3DSA:3.40.50.150 3 199 9.4E-24 T 28-03-2018 CFK41_RS15130 eb4bcd2c0bee734220fc9482a201bc1d 445 Gene3D G3DSA:3.30.497.10 52 241 5.4E-33 T 28-03-2018 CFK41_RS15130 eb4bcd2c0bee734220fc9482a201bc1d 445 Pfam PF00079 Serpin (serine protease inhibitor) 69 441 4.8E-69 T 28-03-2018 IPR023796 Serpin domain CFK41_RS15130 eb4bcd2c0bee734220fc9482a201bc1d 445 SUPERFAMILY SSF56574 66 441 1.57E-69 T 28-03-2018 IPR023796 Serpin domain CFK41_RS15130 eb4bcd2c0bee734220fc9482a201bc1d 445 Gene3D G3DSA:2.30.39.10 242 443 4.6E-38 T 28-03-2018 CFK41_RS15130 eb4bcd2c0bee734220fc9482a201bc1d 445 SMART SM00093 71 441 1.9E-50 T 28-03-2018 IPR023796 Serpin domain CFK41_RS02260 8a53e816ca8d2c460d49db7034086332 472 SUPERFAMILY SSF53738 2 187 2.16E-38 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS02260 8a53e816ca8d2c460d49db7034086332 472 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 136 9.2E-32 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS02260 8a53e816ca8d2c460d49db7034086332 472 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 9.6E-13 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS02260 8a53e816ca8d2c460d49db7034086332 472 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 180 199 9.6E-13 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS02260 8a53e816ca8d2c460d49db7034086332 472 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 214 227 9.6E-13 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS02260 8a53e816ca8d2c460d49db7034086332 472 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 242 257 9.6E-13 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS02260 8a53e816ca8d2c460d49db7034086332 472 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 95 104 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS02260 8a53e816ca8d2c460d49db7034086332 472 Gene3D G3DSA:3.40.120.10 1 165 3.4E-36 T 28-03-2018 CFK41_RS02260 8a53e816ca8d2c460d49db7034086332 472 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 267 377 1.7E-29 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS02260 8a53e816ca8d2c460d49db7034086332 472 SUPERFAMILY SSF55957 394 465 4.32E-13 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS02260 8a53e816ca8d2c460d49db7034086332 472 Gene3D G3DSA:3.40.120.10 166 271 1.8E-27 T 28-03-2018 CFK41_RS02260 8a53e816ca8d2c460d49db7034086332 472 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 163 261 6.5E-24 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS02260 8a53e816ca8d2c460d49db7034086332 472 SUPERFAMILY SSF53738 250 381 1.67E-31 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS02260 8a53e816ca8d2c460d49db7034086332 472 Gene3D G3DSA:3.30.310.50 374 469 4.3E-13 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS02260 8a53e816ca8d2c460d49db7034086332 472 Gene3D G3DSA:3.40.120.10 272 373 6.0E-32 T 28-03-2018 CFK41_RS02260 8a53e816ca8d2c460d49db7034086332 472 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 421 465 8.9E-8 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS07165 127c9405eade7d2fb750eea79d02d301 854 Hamap MF_01588 DNA ligase [ligA]. 17 828 47.723 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CFK41_RS07165 127c9405eade7d2fb750eea79d02d301 854 SUPERFAMILY SSF56091 233 373 1.67E-31 T 28-03-2018 CFK41_RS07165 127c9405eade7d2fb750eea79d02d301 854 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 18 207 4.2E-63 T 28-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 CFK41_RS07165 127c9405eade7d2fb750eea79d02d301 854 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 237 373 3.5E-32 T 28-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 CFK41_RS07165 127c9405eade7d2fb750eea79d02d301 854 SUPERFAMILY SSF47781 653 745 4.82E-25 T 28-03-2018 IPR010994 RuvA domain 2-like CFK41_RS07165 127c9405eade7d2fb750eea79d02d301 854 SUPERFAMILY SSF47781 588 611 4.82E-25 T 28-03-2018 IPR010994 RuvA domain 2-like CFK41_RS07165 127c9405eade7d2fb750eea79d02d301 854 SUPERFAMILY SSF47781 458 524 5.11E-12 T 28-03-2018 IPR010994 RuvA domain 2-like CFK41_RS07165 127c9405eade7d2fb750eea79d02d301 854 SUPERFAMILY SSF56091 17 213 1.84E-62 T 28-03-2018 CFK41_RS07165 127c9405eade7d2fb750eea79d02d301 854 Gene3D G3DSA:1.10.150.20 488 667 1.8E-19 T 28-03-2018 CFK41_RS07165 127c9405eade7d2fb750eea79d02d301 854 Gene3D G3DSA:1.10.150.20 668 734 2.3E-25 T 28-03-2018 CFK41_RS07165 127c9405eade7d2fb750eea79d02d301 854 SMART SM00532 18 504 1.3E-203 T 28-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 CFK41_RS07165 127c9405eade7d2fb750eea79d02d301 854 Pfam PF12826 Helix-hairpin-helix motif 672 735 6.0E-21 T 28-03-2018 CFK41_RS07165 127c9405eade7d2fb750eea79d02d301 854 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 756 827 4.6E-10 T 28-03-2018 IPR001357 BRCT domain CFK41_RS07165 127c9405eade7d2fb750eea79d02d301 854 Gene3D G3DSA:3.30.470.30 132 292 8.9E-42 T 28-03-2018 CFK41_RS07165 127c9405eade7d2fb750eea79d02d301 854 Gene3D G3DSA:3.30.1490.70 293 376 4.7E-27 T 28-03-2018 CFK41_RS07165 127c9405eade7d2fb750eea79d02d301 854 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 376 453 7.3E-30 T 28-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 CFK41_RS07165 127c9405eade7d2fb750eea79d02d301 854 Gene3D G3DSA:1.10.287.610 10 82 1.6E-24 T 28-03-2018 CFK41_RS07165 127c9405eade7d2fb750eea79d02d301 854 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 128 157 - T 28-03-2018 IPR018239 NAD-dependent DNA ligase, active site CFK41_RS07165 127c9405eade7d2fb750eea79d02d301 854 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 463 490 4.3E-7 T 28-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 CFK41_RS07165 127c9405eade7d2fb750eea79d02d301 854 Gene3D G3DSA:3.40.50.10190 735 830 1.3E-16 T 28-03-2018 IPR001357 BRCT domain CFK41_RS07165 127c9405eade7d2fb750eea79d02d301 854 SUPERFAMILY SSF50249 372 456 2.23E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS07165 127c9405eade7d2fb750eea79d02d301 854 SUPERFAMILY SSF52113 754 829 3.92E-16 T 28-03-2018 IPR001357 BRCT domain CFK41_RS07165 127c9405eade7d2fb750eea79d02d301 854 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 386 401 - T 28-03-2018 IPR033136 NAD-dependent DNA ligase, conserved site CFK41_RS07165 127c9405eade7d2fb750eea79d02d301 854 Gene3D G3DSA:2.40.50.140 377 444 2.6E-27 T 28-03-2018 CFK41_RS07165 127c9405eade7d2fb750eea79d02d301 854 SMART SM00292 754 831 4.6E-11 T 28-03-2018 IPR001357 BRCT domain CFK41_RS12565 faaeb60678f064ff672fd93db1cb087c 369 Gene3D G3DSA:3.20.20.70 15 367 1.6E-47 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS12565 faaeb60678f064ff672fd93db1cb087c 369 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 16 297 9.0E-40 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CFK41_RS12565 faaeb60678f064ff672fd93db1cb087c 369 SMART SM01240 14 366 8.4E-20 T 28-03-2018 CFK41_RS12565 faaeb60678f064ff672fd93db1cb087c 369 TIGRFAM TIGR01304 IMP_DH_rel_2: IMP dehydrogenase family protein 4 366 5.7E-169 T 28-03-2018 IPR005992 IMP dehydrogenase-related 2 GO:0016491|GO:0055114 CFK41_RS12565 faaeb60678f064ff672fd93db1cb087c 369 SUPERFAMILY SSF51412 12 77 2.22E-66 T 28-03-2018 CFK41_RS12565 faaeb60678f064ff672fd93db1cb087c 369 SUPERFAMILY SSF51412 113 366 2.22E-66 T 28-03-2018 CFK41_RS09245 962c5504e885dd0b6a4684746fc9d317 653 SMART SM00278 562 581 120.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CFK41_RS09245 962c5504e885dd0b6a4684746fc9d317 653 SMART SM00278 594 613 0.14 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CFK41_RS09245 962c5504e885dd0b6a4684746fc9d317 653 Gene3D G3DSA:4.10.860.10 187 248 1.2E-12 T 28-03-2018 IPR001943 UVR domain GO:0005515 CFK41_RS09245 962c5504e885dd0b6a4684746fc9d317 653 SUPERFAMILY SSF46600 195 246 6.02E-11 T 28-03-2018 IPR001943 UVR domain GO:0005515 CFK41_RS09245 962c5504e885dd0b6a4684746fc9d317 653 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 13 595 8.1E-150 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CFK41_RS09245 962c5504e885dd0b6a4684746fc9d317 653 Pfam PF02151 UvrB/uvrC motif 209 242 1.2E-7 T 28-03-2018 IPR001943 UVR domain GO:0005515 CFK41_RS09245 962c5504e885dd0b6a4684746fc9d317 653 SUPERFAMILY SSF47781 505 615 1.72E-22 T 28-03-2018 IPR010994 RuvA domain 2-like CFK41_RS09245 962c5504e885dd0b6a4684746fc9d317 653 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 386 548 3.8E-49 T 28-03-2018 IPR001162 UvrC family homology region CFK41_RS09245 962c5504e885dd0b6a4684746fc9d317 653 Gene3D G3DSA:1.10.150.20 547 625 1.7E-14 T 28-03-2018 CFK41_RS09245 962c5504e885dd0b6a4684746fc9d317 653 Gene3D G3DSA:3.40.1440.10 5 102 2.1E-22 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CFK41_RS09245 962c5504e885dd0b6a4684746fc9d317 653 Pfam PF01541 GIY-YIG catalytic domain 19 92 1.3E-10 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CFK41_RS09245 962c5504e885dd0b6a4684746fc9d317 653 Pfam PF14520 Helix-hairpin-helix domain 564 615 2.0E-9 T 28-03-2018 CFK41_RS09245 962c5504e885dd0b6a4684746fc9d317 653 SMART SM00465 17 99 9.8E-20 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CFK41_RS09245 962c5504e885dd0b6a4684746fc9d317 653 SUPERFAMILY SSF82771 17 101 3.92E-23 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CFK41_RS09245 962c5504e885dd0b6a4684746fc9d317 653 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 613 28.31 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CFK41_RS16820 0966f47ac3f40fc8cb657803b288e0a3 406 Pfam PF07687 Peptidase dimerisation domain 194 292 7.8E-14 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CFK41_RS16820 0966f47ac3f40fc8cb657803b288e0a3 406 Gene3D G3DSA:3.40.630.10 2 292 7.3E-59 T 28-03-2018 CFK41_RS16820 0966f47ac3f40fc8cb657803b288e0a3 406 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 20 384 2.2E-77 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CFK41_RS16820 0966f47ac3f40fc8cb657803b288e0a3 406 Pfam PF01546 Peptidase family M20/M25/M40 72 392 7.0E-25 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CFK41_RS16820 0966f47ac3f40fc8cb657803b288e0a3 406 SUPERFAMILY SSF55031 194 302 7.72E-28 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CFK41_RS16820 0966f47ac3f40fc8cb657803b288e0a3 406 SUPERFAMILY SSF53187 7 208 9.43E-70 T 28-03-2018 CFK41_RS16820 0966f47ac3f40fc8cb657803b288e0a3 406 SUPERFAMILY SSF53187 311 402 9.43E-70 T 28-03-2018 CFK41_RS16820 0966f47ac3f40fc8cb657803b288e0a3 406 PIRSF PIRSF005962 2 406 1.5E-100 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CFK41_RS16820 0966f47ac3f40fc8cb657803b288e0a3 406 Gene3D G3DSA:3.30.70.360 293 338 0.35 T 28-03-2018 CFK41_RS02990 3defae1b90ed58465faaae9bb3e0a463 741 SMART SM00740 599 665 1.1E-16 T 28-03-2018 IPR005543 PASTA domain CFK41_RS02990 3defae1b90ed58465faaae9bb3e0a463 741 SMART SM00740 464 531 1.4E-5 T 28-03-2018 IPR005543 PASTA domain CFK41_RS02990 3defae1b90ed58465faaae9bb3e0a463 741 SMART SM00740 532 598 2.1E-8 T 28-03-2018 IPR005543 PASTA domain CFK41_RS02990 3defae1b90ed58465faaae9bb3e0a463 741 SMART SM00740 397 463 1.0E-19 T 28-03-2018 IPR005543 PASTA domain CFK41_RS02990 3defae1b90ed58465faaae9bb3e0a463 741 Pfam PF00069 Protein kinase domain 12 268 4.0E-51 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CFK41_RS02990 3defae1b90ed58465faaae9bb3e0a463 741 Pfam PF03793 PASTA domain 603 664 1.5E-17 T 28-03-2018 IPR005543 PASTA domain CFK41_RS02990 3defae1b90ed58465faaae9bb3e0a463 741 Pfam PF03793 PASTA domain 401 463 1.2E-14 T 28-03-2018 IPR005543 PASTA domain CFK41_RS02990 3defae1b90ed58465faaae9bb3e0a463 741 Pfam PF03793 PASTA domain 534 596 1.4E-12 T 28-03-2018 IPR005543 PASTA domain CFK41_RS02990 3defae1b90ed58465faaae9bb3e0a463 741 Pfam PF03793 PASTA domain 469 529 9.4E-12 T 28-03-2018 IPR005543 PASTA domain CFK41_RS02990 3defae1b90ed58465faaae9bb3e0a463 741 Gene3D G3DSA:3.30.200.20 2 104 2.5E-22 T 28-03-2018 CFK41_RS02990 3defae1b90ed58465faaae9bb3e0a463 741 SUPERFAMILY SSF56112 9 286 7.15E-76 T 28-03-2018 IPR011009 Protein kinase-like domain CFK41_RS02990 3defae1b90ed58465faaae9bb3e0a463 741 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 41 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CFK41_RS02990 3defae1b90ed58465faaae9bb3e0a463 741 Gene3D G3DSA:1.10.510.10 105 286 9.2E-50 T 28-03-2018 CFK41_RS02990 3defae1b90ed58465faaae9bb3e0a463 741 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 140 152 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CFK41_RS02990 3defae1b90ed58465faaae9bb3e0a463 741 SMART SM00220 12 280 3.6E-65 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CFK41_RS13575 191c6732905c9c18f9bf553b8da18aed 685 Gene3D G3DSA:1.10.3470.10 360 685 6.1E-65 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CFK41_RS13575 191c6732905c9c18f9bf553b8da18aed 685 Gene3D G3DSA:1.10.3470.10 11 350 7.8E-49 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CFK41_RS13575 191c6732905c9c18f9bf553b8da18aed 685 SUPERFAMILY SSF81345 15 342 5.1E-53 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CFK41_RS13575 191c6732905c9c18f9bf553b8da18aed 685 SUPERFAMILY SSF81345 359 682 2.09E-71 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CFK41_RS13575 191c6732905c9c18f9bf553b8da18aed 685 Pfam PF01032 FecCD transport family 375 682 8.2E-78 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CFK41_RS13575 191c6732905c9c18f9bf553b8da18aed 685 Pfam PF01032 FecCD transport family 24 342 3.4E-63 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CFK41_RS04860 bbb5b313b01370d7205b360e77bbd3e2 828 SUPERFAMILY SSF52540 317 527 1.68E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS04860 bbb5b313b01370d7205b360e77bbd3e2 828 ProSitePatterns PS00211 ABC transporters family signature. 437 451 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS04860 bbb5b313b01370d7205b360e77bbd3e2 828 Pfam PF00005 ABC transporter 53 199 5.7E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS04860 bbb5b313b01370d7205b360e77bbd3e2 828 Pfam PF00005 ABC transporter 341 463 4.2E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS04860 bbb5b313b01370d7205b360e77bbd3e2 828 Pfam PF02361 Cobalt transport protein 593 792 7.7E-13 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CFK41_RS04860 bbb5b313b01370d7205b360e77bbd3e2 828 SMART SM00382 350 512 8.1E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS04860 bbb5b313b01370d7205b360e77bbd3e2 828 SMART SM00382 57 254 2.1E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS04860 bbb5b313b01370d7205b360e77bbd3e2 828 Gene3D G3DSA:3.40.50.300 15 275 1.2E-36 T 28-03-2018 CFK41_RS04860 bbb5b313b01370d7205b360e77bbd3e2 828 Gene3D G3DSA:3.40.50.300 323 578 2.6E-43 T 28-03-2018 CFK41_RS04860 bbb5b313b01370d7205b360e77bbd3e2 828 ProSitePatterns PS00211 ABC transporters family signature. 171 185 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS04860 bbb5b313b01370d7205b360e77bbd3e2 828 SUPERFAMILY SSF52540 15 269 1.25E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS06935 9c1783480c3c7d35dc6d9d89530a495e 352 SUPERFAMILY SSF53067 106 319 1.07E-38 T 28-03-2018 CFK41_RS06935 9c1783480c3c7d35dc6d9d89530a495e 352 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 9 322 2.1E-118 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CFK41_RS06935 9c1783480c3c7d35dc6d9d89530a495e 352 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 81 101 3.3E-47 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CFK41_RS06935 9c1783480c3c7d35dc6d9d89530a495e 352 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 136 148 3.3E-47 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CFK41_RS06935 9c1783480c3c7d35dc6d9d89530a495e 352 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 10 23 3.3E-47 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CFK41_RS06935 9c1783480c3c7d35dc6d9d89530a495e 352 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 274 283 3.3E-47 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CFK41_RS06935 9c1783480c3c7d35dc6d9d89530a495e 352 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 102 121 3.3E-47 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CFK41_RS06935 9c1783480c3c7d35dc6d9d89530a495e 352 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 161 182 3.3E-47 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CFK41_RS06935 9c1783480c3c7d35dc6d9d89530a495e 352 SUPERFAMILY SSF53067 9 127 4.27E-27 T 28-03-2018 CFK41_RS06935 9c1783480c3c7d35dc6d9d89530a495e 352 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 10 317 1.7E-94 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CFK41_RS06935 9c1783480c3c7d35dc6d9d89530a495e 352 Pfam PF00814 Glycoprotease family 32 317 4.0E-91 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CFK41_RS06935 9c1783480c3c7d35dc6d9d89530a495e 352 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 7 343 57.067 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CFK41_RS06935 9c1783480c3c7d35dc6d9d89530a495e 352 Gene3D G3DSA:3.30.420.40 7 147 2.6E-32 T 28-03-2018 CFK41_RS06935 9c1783480c3c7d35dc6d9d89530a495e 352 Gene3D G3DSA:3.30.420.40 148 300 2.1E-19 T 28-03-2018 CFK41_RS06935 9c1783480c3c7d35dc6d9d89530a495e 352 ProSitePatterns PS01016 Glycoprotease family signature. 101 121 - T 28-03-2018 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 CFK41_RS11065 6033e0a526b39d824903337305f03bc4 175 Pfam PF13673 Acetyltransferase (GNAT) domain 70 156 2.7E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS11065 6033e0a526b39d824903337305f03bc4 175 SUPERFAMILY SSF55729 12 157 1.67E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS11065 6033e0a526b39d824903337305f03bc4 175 Gene3D G3DSA:3.40.630.30 1 175 1.3E-25 T 28-03-2018 CFK41_RS16015 ca62ead9d0574c32c38d50d011cdac3b 283 SUPERFAMILY SSF54427 167 275 9.71E-10 T 28-03-2018 IPR032710 NTF2-like domain CFK41_RS16015 ca62ead9d0574c32c38d50d011cdac3b 283 Pfam PF08281 Sigma-70, region 4 104 154 7.6E-8 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS16015 ca62ead9d0574c32c38d50d011cdac3b 283 SUPERFAMILY SSF88659 98 155 4.49E-8 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS16015 ca62ead9d0574c32c38d50d011cdac3b 283 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 156 3.0E-16 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS16015 ca62ead9d0574c32c38d50d011cdac3b 283 Gene3D G3DSA:1.10.1740.10 1 104 4.8E-14 T 28-03-2018 CFK41_RS16015 ca62ead9d0574c32c38d50d011cdac3b 283 Pfam PF04542 Sigma-70 region 2 13 74 2.0E-14 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS16015 ca62ead9d0574c32c38d50d011cdac3b 283 Gene3D G3DSA:3.10.450.50 149 279 6.2E-11 T 28-03-2018 CFK41_RS16015 ca62ead9d0574c32c38d50d011cdac3b 283 Gene3D G3DSA:1.10.10.10 105 148 1.8E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS16015 ca62ead9d0574c32c38d50d011cdac3b 283 SUPERFAMILY SSF88946 6 91 4.71E-14 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS00660 01f09c69bac5ff9ff73c675dccb5b9c9 265 Gene3D G3DSA:1.10.10.10 2 76 3.3E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS00660 01f09c69bac5ff9ff73c675dccb5b9c9 265 Gene3D G3DSA:3.30.450.40 77 264 6.8E-46 T 28-03-2018 IPR029016 GAF domain-like CFK41_RS00660 01f09c69bac5ff9ff73c675dccb5b9c9 265 Pfam PF01614 Bacterial transcriptional regulator 124 250 2.1E-22 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CFK41_RS00660 01f09c69bac5ff9ff73c675dccb5b9c9 265 SUPERFAMILY SSF55781 72 254 4.38E-37 T 28-03-2018 IPR029016 GAF domain-like CFK41_RS00660 01f09c69bac5ff9ff73c675dccb5b9c9 265 Pfam PF09339 IclR helix-turn-helix domain 12 55 6.2E-11 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CFK41_RS00660 01f09c69bac5ff9ff73c675dccb5b9c9 265 SMART SM00346 6 96 3.7E-6 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CFK41_RS00660 01f09c69bac5ff9ff73c675dccb5b9c9 265 SUPERFAMILY SSF46785 6 80 5.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS06410 ebd8387fdc43085b80c4e1c459996111 497 Gene3D G3DSA:3.30.565.10 284 492 9.6E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS06410 ebd8387fdc43085b80c4e1c459996111 497 Pfam PF07568 Histidine kinase 292 358 6.4E-22 T 28-03-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain CFK41_RS06410 ebd8387fdc43085b80c4e1c459996111 497 Pfam PF08448 PAS fold 173 278 4.4E-7 T 28-03-2018 IPR013656 PAS fold-4 CFK41_RS06410 ebd8387fdc43085b80c4e1c459996111 497 SUPERFAMILY SSF55874 398 488 1.7E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS06410 ebd8387fdc43085b80c4e1c459996111 497 SMART SM00911 292 376 0.0035 T 28-03-2018 IPR011102 Signal transduction histidine kinase, HWE region GO:0004673 CFK41_RS06410 ebd8387fdc43085b80c4e1c459996111 497 Gene3D G3DSA:3.30.450.20 170 283 6.0E-10 T 28-03-2018 CFK41_RS06410 ebd8387fdc43085b80c4e1c459996111 497 SMART SM00387 399 496 2.7E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS06410 ebd8387fdc43085b80c4e1c459996111 497 SUPERFAMILY SSF55785 175 283 1.51E-5 T 28-03-2018 IPR000014 PAS domain CFK41_RS06410 ebd8387fdc43085b80c4e1c459996111 497 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 402 488 9.6E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS06410 ebd8387fdc43085b80c4e1c459996111 497 Pfam PF12282 Signal transduction histidine kinase 4 140 2.0E-33 T 28-03-2018 IPR022066 Signal transduction histidine kinase CFK41_RS07470 4daad289312845300db3621b8e88cd04 250 Gene3D G3DSA:1.10.1520.10 23 168 2.1E-39 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CFK41_RS07470 4daad289312845300db3621b8e88cd04 250 Hamap MF_00104 Ribonuclease 3 [rnc]. 16 235 27.488 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CFK41_RS07470 4daad289312845300db3621b8e88cd04 250 Pfam PF14622 Ribonuclease-III-like 34 158 1.6E-35 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CFK41_RS07470 4daad289312845300db3621b8e88cd04 250 SMART SM00535 34 167 2.8E-52 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CFK41_RS07470 4daad289312845300db3621b8e88cd04 250 Pfam PF00035 Double-stranded RNA binding motif 175 236 2.2E-11 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain CFK41_RS07470 4daad289312845300db3621b8e88cd04 250 SUPERFAMILY SSF54768 128 238 1.08E-19 T 28-03-2018 CFK41_RS07470 4daad289312845300db3621b8e88cd04 250 Gene3D G3DSA:3.30.160.20 169 243 1.1E-18 T 28-03-2018 CFK41_RS07470 4daad289312845300db3621b8e88cd04 250 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 28 235 2.3E-65 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CFK41_RS07470 4daad289312845300db3621b8e88cd04 250 SMART SM00358 174 239 1.1E-17 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain CFK41_RS07470 4daad289312845300db3621b8e88cd04 250 SUPERFAMILY SSF69065 29 171 2.44E-44 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CFK41_RS07470 4daad289312845300db3621b8e88cd04 250 ProSitePatterns PS00517 Ribonuclease III family signature. 56 64 - T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CFK41_RS04660 c563070a797805ad3137f812d7e01920 180 Gene3D G3DSA:3.90.930.12 85 180 3.1E-39 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04660 c563070a797805ad3137f812d7e01920 180 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 178 36.981 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CFK41_RS04660 c563070a797805ad3137f812d7e01920 180 Gene3D G3DSA:3.90.930.12 2 84 3.3E-25 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04660 c563070a797805ad3137f812d7e01920 180 Pfam PF00347 Ribosomal protein L6 17 84 2.6E-15 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04660 c563070a797805ad3137f812d7e01920 180 Pfam PF00347 Ribosomal protein L6 92 166 7.2E-20 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04660 c563070a797805ad3137f812d7e01920 180 SUPERFAMILY SSF56053 1 84 3.12E-21 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04660 c563070a797805ad3137f812d7e01920 180 SUPERFAMILY SSF56053 85 178 5.1E-35 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04660 c563070a797805ad3137f812d7e01920 180 PIRSF PIRSF002162 1 179 2.4E-46 T 28-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04660 c563070a797805ad3137f812d7e01920 180 PRINTS PR00059 Ribosomal protein L6 signature 143 164 3.6E-33 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CFK41_RS04660 c563070a797805ad3137f812d7e01920 180 PRINTS PR00059 Ribosomal protein L6 signature 73 98 3.6E-33 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CFK41_RS04660 c563070a797805ad3137f812d7e01920 180 PRINTS PR00059 Ribosomal protein L6 signature 101 117 3.6E-33 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CFK41_RS04660 c563070a797805ad3137f812d7e01920 180 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 178 1.2E-69 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CFK41_RS04660 c563070a797805ad3137f812d7e01920 180 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 156 164 - T 28-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS02975 927c0873389d32c08a5a2a33cd7dbda1 269 Gene3D G3DSA:2.40.260.10 55 246 1.2E-44 T 28-03-2018 IPR023365 Sortase domain CFK41_RS02975 927c0873389d32c08a5a2a33cd7dbda1 269 SUPERFAMILY SSF63817 87 231 1.29E-33 T 28-03-2018 IPR023365 Sortase domain CFK41_RS02975 927c0873389d32c08a5a2a33cd7dbda1 269 TIGRFAM TIGR01076 sortase_fam: sortase 99 235 4.1E-20 T 28-03-2018 IPR005754 Sortase family CFK41_RS02975 927c0873389d32c08a5a2a33cd7dbda1 269 Pfam PF04203 Sortase family 99 229 6.4E-32 T 28-03-2018 IPR005754 Sortase family CFK41_RS17640 05793e358355d3dec22b3b5a0c10f59c 353 Gene3D G3DSA:3.30.360.10 136 353 3.8E-43 T 28-03-2018 CFK41_RS17640 05793e358355d3dec22b3b5a0c10f59c 353 SUPERFAMILY SSF55347 127 316 2.45E-29 T 28-03-2018 CFK41_RS17640 05793e358355d3dec22b3b5a0c10f59c 353 Gene3D G3DSA:3.40.50.720 1 135 3.4E-45 T 28-03-2018 CFK41_RS17640 05793e358355d3dec22b3b5a0c10f59c 353 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 123 1.3E-32 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS17640 05793e358355d3dec22b3b5a0c10f59c 353 SUPERFAMILY SSF51735 3 153 2.05E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS17640 05793e358355d3dec22b3b5a0c10f59c 353 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 135 206 5.4E-8 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CFK41_RS09665 98c7141fe6c9957a8c2e5a6fa87863f4 925 SUPERFAMILY SSF53732 5 414 1.31E-220 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS09665 98c7141fe6c9957a8c2e5a6fa87863f4 925 SUPERFAMILY SSF53732 442 656 1.31E-220 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS09665 98c7141fe6c9957a8c2e5a6fa87863f4 925 Gene3D G3DSA:3.30.499.10 27 235 4.0E-73 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS09665 98c7141fe6c9957a8c2e5a6fa87863f4 925 Gene3D G3DSA:3.20.19.10 682 924 7.6E-94 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CFK41_RS09665 98c7141fe6c9957a8c2e5a6fa87863f4 925 Pfam PF00694 Aconitase C-terminal domain 721 848 7.4E-46 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS09665 98c7141fe6c9957a8c2e5a6fa87863f4 925 Gene3D G3DSA:3.40.1060.10 236 367 5.5E-44 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS09665 98c7141fe6c9957a8c2e5a6fa87863f4 925 ProSitePatterns PS01244 Aconitase family signature 2. 522 535 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CFK41_RS09665 98c7141fe6c9957a8c2e5a6fa87863f4 925 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 23 922 0.0 T 28-03-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 CFK41_RS09665 98c7141fe6c9957a8c2e5a6fa87863f4 925 PRINTS PR00415 Aconitase family signature 213 228 1.1E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS09665 98c7141fe6c9957a8c2e5a6fa87863f4 925 PRINTS PR00415 Aconitase family signature 166 174 1.1E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS09665 98c7141fe6c9957a8c2e5a6fa87863f4 925 PRINTS PR00415 Aconitase family signature 142 155 1.1E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS09665 98c7141fe6c9957a8c2e5a6fa87863f4 925 PRINTS PR00415 Aconitase family signature 199 212 1.1E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS09665 98c7141fe6c9957a8c2e5a6fa87863f4 925 PRINTS PR00415 Aconitase family signature 522 535 1.1E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS09665 98c7141fe6c9957a8c2e5a6fa87863f4 925 PRINTS PR00415 Aconitase family signature 289 302 1.1E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS09665 98c7141fe6c9957a8c2e5a6fa87863f4 925 PRINTS PR00415 Aconitase family signature 460 471 1.1E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS09665 98c7141fe6c9957a8c2e5a6fa87863f4 925 PRINTS PR00415 Aconitase family signature 275 288 1.1E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS09665 98c7141fe6c9957a8c2e5a6fa87863f4 925 PRINTS PR00415 Aconitase family signature 368 382 1.1E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS09665 98c7141fe6c9957a8c2e5a6fa87863f4 925 Gene3D G3DSA:3.30.499.10 368 605 1.3E-65 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS09665 98c7141fe6c9957a8c2e5a6fa87863f4 925 Pfam PF00330 Aconitase family (aconitate hydratase) 74 591 1.0E-175 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS09665 98c7141fe6c9957a8c2e5a6fa87863f4 925 SUPERFAMILY SSF52016 660 922 7.65E-86 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CFK41_RS09665 98c7141fe6c9957a8c2e5a6fa87863f4 925 ProSitePatterns PS00450 Aconitase family signature 1. 456 472 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CFK41_RS13310 a34f8acc0dbec5196560e94c8b81811d 302 Gene3D G3DSA:3.40.190.10 153 230 2.9E-7 T 28-03-2018 CFK41_RS13310 a34f8acc0dbec5196560e94c8b81811d 302 SUPERFAMILY SSF53850 43 268 1.74E-36 T 28-03-2018 CFK41_RS13310 a34f8acc0dbec5196560e94c8b81811d 302 Gene3D G3DSA:3.40.190.10 42 152 7.6E-22 T 28-03-2018 CFK41_RS13310 a34f8acc0dbec5196560e94c8b81811d 302 SMART SM00062 52 273 3.4E-25 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CFK41_RS13310 a34f8acc0dbec5196560e94c8b81811d 302 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 53 267 7.5E-36 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CFK41_RS09030 2debe651f92559675bb9d61480b71b5b 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.7E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CFK41_RS09030 2debe651f92559675bb9d61480b71b5b 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.7E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CFK41_RS09030 2debe651f92559675bb9d61480b71b5b 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.7E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CFK41_RS09030 2debe651f92559675bb9d61480b71b5b 296 Pfam PF03466 LysR substrate binding domain 87 286 9.0E-41 T 28-03-2018 IPR005119 LysR, substrate-binding CFK41_RS09030 2debe651f92559675bb9d61480b71b5b 296 SUPERFAMILY SSF53850 88 286 1.36E-38 T 28-03-2018 CFK41_RS09030 2debe651f92559675bb9d61480b71b5b 296 Gene3D G3DSA:3.40.190.10 179 267 1.3E-19 T 28-03-2018 CFK41_RS09030 2debe651f92559675bb9d61480b71b5b 296 Gene3D G3DSA:3.40.190.10 87 178 2.1E-25 T 28-03-2018 CFK41_RS09030 2debe651f92559675bb9d61480b71b5b 296 SUPERFAMILY SSF46785 2 87 8.9E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS09030 2debe651f92559675bb9d61480b71b5b 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.5E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CFK41_RS09030 2debe651f92559675bb9d61480b71b5b 296 Gene3D G3DSA:1.10.10.10 1 83 3.7E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS02495 d6586e74c73061cd766f5c56b4987d50 417 Gene3D G3DSA:3.40.50.720 4 206 1.6E-41 T 28-03-2018 CFK41_RS02495 d6586e74c73061cd766f5c56b4987d50 417 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 208 295 2.0E-26 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CFK41_RS02495 d6586e74c73061cd766f5c56b4987d50 417 PIRSF PIRSF000124 8 415 1.5E-76 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CFK41_RS02495 d6586e74c73061cd766f5c56b4987d50 417 SMART SM00984 318 417 3.0E-19 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CFK41_RS02495 d6586e74c73061cd766f5c56b4987d50 417 Gene3D G3DSA:3.40.50.720 232 417 1.6E-51 T 28-03-2018 CFK41_RS02495 d6586e74c73061cd766f5c56b4987d50 417 SUPERFAMILY SSF48179 208 300 6.12E-28 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CFK41_RS02495 d6586e74c73061cd766f5c56b4987d50 417 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 9 413 2.0E-118 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CFK41_RS02495 d6586e74c73061cd766f5c56b4987d50 417 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 318 415 2.8E-18 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CFK41_RS02495 d6586e74c73061cd766f5c56b4987d50 417 Gene3D G3DSA:1.20.5.170 208 231 5.9E-14 T 28-03-2018 CFK41_RS02495 d6586e74c73061cd766f5c56b4987d50 417 SUPERFAMILY SSF51735 9 200 1.71E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS02495 d6586e74c73061cd766f5c56b4987d50 417 PIRSF PIRSF500136 2 417 2.5E-138 T 28-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 CFK41_RS02495 d6586e74c73061cd766f5c56b4987d50 417 SUPERFAMILY SSF52413 305 416 6.41E-23 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CFK41_RS02495 d6586e74c73061cd766f5c56b4987d50 417 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 9 187 2.6E-49 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CFK41_RS00755 c4d2deb5844600cd0cca43057797c0dc 276 Pfam PF08241 Methyltransferase domain 49 146 1.3E-21 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CFK41_RS00755 c4d2deb5844600cd0cca43057797c0dc 276 SUPERFAMILY SSF53335 16 216 6.44E-41 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS00755 c4d2deb5844600cd0cca43057797c0dc 276 Gene3D G3DSA:3.40.50.150 11 269 8.1E-38 T 28-03-2018 CFK41_RS01500 4813b8e60b6b3d53f96aa9afea5702ba 519 Gene3D G3DSA:3.40.190.10 163 514 3.8E-17 T 28-03-2018 CFK41_RS01500 4813b8e60b6b3d53f96aa9afea5702ba 519 SUPERFAMILY SSF53850 25 512 6.24E-42 T 28-03-2018 CFK41_RS01500 4813b8e60b6b3d53f96aa9afea5702ba 519 Pfam PF12010 Domain of unknown function (DUF3502) 380 514 5.9E-21 T 28-03-2018 IPR022627 Domain of unknown function DUF3502 CFK41_RS12265 80dfd8eb36c093c56ee558d8d0a14e27 226 Pfam PF01895 PhoU domain 16 102 1.7E-15 T 28-03-2018 IPR026022 PhoU domain CFK41_RS12265 80dfd8eb36c093c56ee558d8d0a14e27 226 Pfam PF01895 PhoU domain 121 205 1.0E-11 T 28-03-2018 IPR026022 PhoU domain CFK41_RS12265 80dfd8eb36c093c56ee558d8d0a14e27 226 Gene3D G3DSA:1.20.58.220 114 223 5.3E-19 T 28-03-2018 CFK41_RS12265 80dfd8eb36c093c56ee558d8d0a14e27 226 Gene3D G3DSA:1.20.58.220 1 111 1.2E-19 T 28-03-2018 CFK41_RS12265 80dfd8eb36c093c56ee558d8d0a14e27 226 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 212 2.1E-51 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CFK41_RS12265 80dfd8eb36c093c56ee558d8d0a14e27 226 SUPERFAMILY SSF109755 2 215 1.15E-50 T 28-03-2018 CFK41_RS12265 80dfd8eb36c093c56ee558d8d0a14e27 226 PIRSF PIRSF003107 1 217 1.9E-50 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CFK41_RS01810 1f057a44d592d5cd130918a651dd1909 363 SUPERFAMILY SSF51395 4 353 6.48E-114 T 28-03-2018 CFK41_RS01810 1f057a44d592d5cd130918a651dd1909 363 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 346 9.6E-76 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CFK41_RS01810 1f057a44d592d5cd130918a651dd1909 363 Gene3D G3DSA:3.20.20.70 1 361 1.6E-122 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS10040 3dc75dc651fb68dc7ff1fd2bbda5f36e 859 Gene3D G3DSA:3.20.20.80 33 763 1.1E-97 T 28-03-2018 CFK41_RS10040 3dc75dc651fb68dc7ff1fd2bbda5f36e 859 Pfam PF00128 Alpha amylase, catalytic domain 51 147 1.9E-15 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CFK41_RS10040 3dc75dc651fb68dc7ff1fd2bbda5f36e 859 SMART SM00642 36 494 2.0E-6 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CFK41_RS10040 3dc75dc651fb68dc7ff1fd2bbda5f36e 859 SUPERFAMILY SSF51445 28 417 1.23E-105 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS10040 3dc75dc651fb68dc7ff1fd2bbda5f36e 859 SUPERFAMILY SSF51445 479 763 1.23E-105 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS10040 3dc75dc651fb68dc7ff1fd2bbda5f36e 859 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 29 851 1.8E-247 T 28-03-2018 IPR012767 Maltooligosyl trehalose synthase KEGG: 00500+5.4.99.15|MetaCyc: PWY-2661 CFK41_RS10610 e535394d51d2b31886b1d3e0c4ab19ab 265 Pfam PF00106 short chain dehydrogenase 1 190 1.1E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS10610 e535394d51d2b31886b1d3e0c4ab19ab 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 8.0E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS10610 e535394d51d2b31886b1d3e0c4ab19ab 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 1 12 8.0E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS10610 e535394d51d2b31886b1d3e0c4ab19ab 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 8.0E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS10610 e535394d51d2b31886b1d3e0c4ab19ab 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 8.0E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS10610 e535394d51d2b31886b1d3e0c4ab19ab 265 Gene3D G3DSA:3.40.50.720 1 254 8.1E-52 T 28-03-2018 CFK41_RS10610 e535394d51d2b31886b1d3e0c4ab19ab 265 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CFK41_RS10610 e535394d51d2b31886b1d3e0c4ab19ab 265 SUPERFAMILY SSF51735 1 243 8.37E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS10505 b3d7ddff0199c3dc287898cf929d393c 702 SUPERFAMILY SSF52540 168 416 9.55E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS10505 b3d7ddff0199c3dc287898cf929d393c 702 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 557 575 4.3E-5 T 28-03-2018 CFK41_RS10505 b3d7ddff0199c3dc287898cf929d393c 702 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 507 526 4.3E-5 T 28-03-2018 CFK41_RS10505 b3d7ddff0199c3dc287898cf929d393c 702 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 217 236 4.3E-5 T 28-03-2018 CFK41_RS10505 b3d7ddff0199c3dc287898cf929d393c 702 Gene3D G3DSA:1.10.8.60 353 439 1.1E-19 T 28-03-2018 CFK41_RS10505 b3d7ddff0199c3dc287898cf929d393c 702 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 14 634 35.362 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CFK41_RS10505 b3d7ddff0199c3dc287898cf929d393c 702 ProSitePatterns PS00674 AAA-protein family signature. 316 334 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CFK41_RS10505 b3d7ddff0199c3dc287898cf929d393c 702 SMART SM00382 209 348 3.9E-24 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS10505 b3d7ddff0199c3dc287898cf929d393c 702 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 126 616 8.0E-219 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CFK41_RS10505 b3d7ddff0199c3dc287898cf929d393c 702 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 213 345 2.7E-46 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CFK41_RS10505 b3d7ddff0199c3dc287898cf929d393c 702 Pfam PF01434 Peptidase family M41 408 615 1.0E-70 T 28-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 CFK41_RS10505 b3d7ddff0199c3dc287898cf929d393c 702 Gene3D G3DSA:3.40.50.300 148 352 1.2E-61 T 28-03-2018 CFK41_RS10505 b3d7ddff0199c3dc287898cf929d393c 702 SUPERFAMILY SSF140990 427 627 1.83E-65 T 28-03-2018 CFK41_RS10400 c6e69ed8540f84caee7dd725fcea36f3 860 Gene3D G3DSA:1.10.1780.10 1 79 2.4E-28 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CFK41_RS10400 c6e69ed8540f84caee7dd725fcea36f3 860 Gene3D G3DSA:1.10.8.60 719 823 1.2E-23 T 28-03-2018 CFK41_RS10400 c6e69ed8540f84caee7dd725fcea36f3 860 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 209 330 2.2E-12 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CFK41_RS10400 c6e69ed8540f84caee7dd725fcea36f3 860 SMART SM00382 204 347 1.3E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS10400 c6e69ed8540f84caee7dd725fcea36f3 860 SMART SM00382 541 691 6.6E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS10400 c6e69ed8540f84caee7dd725fcea36f3 860 Pfam PF07724 AAA domain (Cdc48 subfamily) 541 712 2.4E-52 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CFK41_RS10400 c6e69ed8540f84caee7dd725fcea36f3 860 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 652 666 5.7E-40 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CFK41_RS10400 c6e69ed8540f84caee7dd725fcea36f3 860 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 619 637 5.7E-40 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CFK41_RS10400 c6e69ed8540f84caee7dd725fcea36f3 860 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 590 608 5.7E-40 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CFK41_RS10400 c6e69ed8540f84caee7dd725fcea36f3 860 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 545 563 5.7E-40 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CFK41_RS10400 c6e69ed8540f84caee7dd725fcea36f3 860 Gene3D G3DSA:1.10.1780.10 80 196 4.7E-28 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CFK41_RS10400 c6e69ed8540f84caee7dd725fcea36f3 860 Gene3D G3DSA:1.10.8.60 348 491 5.3E-40 T 28-03-2018 CFK41_RS10400 c6e69ed8540f84caee7dd725fcea36f3 860 SUPERFAMILY SSF81923 3 141 3.14E-30 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CFK41_RS10400 c6e69ed8540f84caee7dd725fcea36f3 860 SMART SM01086 719 812 1.4E-34 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CFK41_RS10400 c6e69ed8540f84caee7dd725fcea36f3 860 Gene3D G3DSA:3.40.50.300 496 718 2.0E-56 T 28-03-2018 CFK41_RS10400 c6e69ed8540f84caee7dd725fcea36f3 860 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 719 799 5.4E-26 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CFK41_RS10400 c6e69ed8540f84caee7dd725fcea36f3 860 SUPERFAMILY SSF52540 167 461 3.38E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS10400 c6e69ed8540f84caee7dd725fcea36f3 860 Pfam PF02151 UvrB/uvrC motif 422 455 2.7E-6 T 28-03-2018 IPR001943 UVR domain GO:0005515 CFK41_RS10400 c6e69ed8540f84caee7dd725fcea36f3 860 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 141 1.1E-15 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CFK41_RS10400 c6e69ed8540f84caee7dd725fcea36f3 860 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 68 1.6E-17 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CFK41_RS10400 c6e69ed8540f84caee7dd725fcea36f3 860 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 299 311 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CFK41_RS10400 c6e69ed8540f84caee7dd725fcea36f3 860 Gene3D G3DSA:3.40.50.300 197 346 9.2E-18 T 28-03-2018 CFK41_RS10400 c6e69ed8540f84caee7dd725fcea36f3 860 SUPERFAMILY SSF52540 490 801 6.04E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS06485 bdbf82438ca10c6b58a19a6b1d21d08d 381 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 5 364 3.7E-90 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CFK41_RS06485 bdbf82438ca10c6b58a19a6b1d21d08d 381 Pfam PF02595 Glycerate kinase family 5 364 6.5E-106 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CFK41_RS06485 bdbf82438ca10c6b58a19a6b1d21d08d 381 PIRSF PIRSF006078 3 363 3.9E-99 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CFK41_RS06485 bdbf82438ca10c6b58a19a6b1d21d08d 381 SUPERFAMILY SSF110738 5 365 1.57E-94 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CFK41_RS06485 bdbf82438ca10c6b58a19a6b1d21d08d 381 Gene3D G3DSA:3.90.1510.10 44 272 1.2E-66 T 28-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 CFK41_RS16595 2af6cb3ac9cda03245bee0f090747b46 425 Gene3D G3DSA:1.20.1250.20 216 413 2.5E-14 T 28-03-2018 CFK41_RS16595 2af6cb3ac9cda03245bee0f090747b46 425 Pfam PF07690 Major Facilitator Superfamily 32 222 7.5E-21 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS16595 2af6cb3ac9cda03245bee0f090747b46 425 Gene3D G3DSA:1.20.1250.20 3 215 2.7E-25 T 28-03-2018 CFK41_RS16595 2af6cb3ac9cda03245bee0f090747b46 425 SUPERFAMILY SSF103473 17 408 4.84E-48 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS00290 6a9a3d2aa46b9e2a25b7100635c4c9fa 224 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 79 5.2E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS00290 6a9a3d2aa46b9e2a25b7100635c4c9fa 224 SUPERFAMILY SSF46785 12 83 2.72E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS00290 6a9a3d2aa46b9e2a25b7100635c4c9fa 224 Gene3D G3DSA:1.10.10.10 6 81 1.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS00290 6a9a3d2aa46b9e2a25b7100635c4c9fa 224 SUPERFAMILY SSF48008 86 216 7.32E-20 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS00290 6a9a3d2aa46b9e2a25b7100635c4c9fa 224 Pfam PF07729 FCD domain 89 213 2.4E-19 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS00290 6a9a3d2aa46b9e2a25b7100635c4c9fa 224 SMART SM00345 21 79 5.7E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS00290 6a9a3d2aa46b9e2a25b7100635c4c9fa 224 SMART SM00895 89 214 8.2E-12 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS00290 6a9a3d2aa46b9e2a25b7100635c4c9fa 224 Gene3D G3DSA:1.20.120.530 82 224 7.1E-23 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS05105 aaff49731f528d57ab5fa03ade75fd14 109 SUPERFAMILY SSF54427 5 101 8.79E-13 T 28-03-2018 IPR032710 NTF2-like domain CFK41_RS05105 aaff49731f528d57ab5fa03ade75fd14 109 Gene3D G3DSA:3.10.450.50 3 107 1.5E-13 T 28-03-2018 CFK41_RS05105 aaff49731f528d57ab5fa03ade75fd14 109 Pfam PF12680 SnoaL-like domain 10 90 1.1E-6 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CFK41_RS01110 75b983dde582a5496e3e5b0bd7e06047 147 SUPERFAMILY SSF46785 13 117 3.35E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS01110 75b983dde582a5496e3e5b0bd7e06047 147 Pfam PF12840 Helix-turn-helix domain 16 74 8.1E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS01110 75b983dde582a5496e3e5b0bd7e06047 147 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 66 81 1.8E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS01110 75b983dde582a5496e3e5b0bd7e06047 147 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 51 66 1.8E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS01110 75b983dde582a5496e3e5b0bd7e06047 147 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 19 34 1.8E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS01110 75b983dde582a5496e3e5b0bd7e06047 147 Gene3D G3DSA:1.10.10.10 12 118 9.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS01110 75b983dde582a5496e3e5b0bd7e06047 147 SMART SM00418 17 98 7.5E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS12335 78ce1524eb560f4a68060777340bb4a3 475 SUPERFAMILY SSF51905 5 384 2.1E-34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS12335 78ce1524eb560f4a68060777340bb4a3 475 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 43 326 5.9E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS12335 78ce1524eb560f4a68060777340bb4a3 475 SUPERFAMILY SSF55424 360 473 1.03E-32 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CFK41_RS12335 78ce1524eb560f4a68060777340bb4a3 475 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 44 54 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CFK41_RS12335 78ce1524eb560f4a68060777340bb4a3 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 4.0E-13 T 28-03-2018 CFK41_RS12335 78ce1524eb560f4a68060777340bb4a3 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 4.0E-13 T 28-03-2018 CFK41_RS12335 78ce1524eb560f4a68060777340bb4a3 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 184 202 4.0E-13 T 28-03-2018 CFK41_RS12335 78ce1524eb560f4a68060777340bb4a3 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 270 286 4.0E-13 T 28-03-2018 CFK41_RS12335 78ce1524eb560f4a68060777340bb4a3 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 356 377 3.1E-46 T 28-03-2018 CFK41_RS12335 78ce1524eb560f4a68060777340bb4a3 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 148 157 3.1E-46 T 28-03-2018 CFK41_RS12335 78ce1524eb560f4a68060777340bb4a3 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 421 436 3.1E-46 T 28-03-2018 CFK41_RS12335 78ce1524eb560f4a68060777340bb4a3 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 184 209 3.1E-46 T 28-03-2018 CFK41_RS12335 78ce1524eb560f4a68060777340bb4a3 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 319 326 3.1E-46 T 28-03-2018 CFK41_RS12335 78ce1524eb560f4a68060777340bb4a3 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 271 285 3.1E-46 T 28-03-2018 CFK41_RS12335 78ce1524eb560f4a68060777340bb4a3 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 3.1E-46 T 28-03-2018 CFK41_RS12335 78ce1524eb560f4a68060777340bb4a3 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 43 58 3.1E-46 T 28-03-2018 CFK41_RS12335 78ce1524eb560f4a68060777340bb4a3 475 Gene3D G3DSA:3.40.50.720 173 349 3.3E-23 T 28-03-2018 CFK41_RS12335 78ce1524eb560f4a68060777340bb4a3 475 Gene3D G3DSA:3.30.390.30 359 475 6.2E-35 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CFK41_RS12335 78ce1524eb560f4a68060777340bb4a3 475 Gene3D G3DSA:3.50.50.60 4 172 3.3E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS12335 78ce1524eb560f4a68060777340bb4a3 475 PIRSF PIRSF000350 1 462 1.4E-76 T 28-03-2018 CFK41_RS12335 78ce1524eb560f4a68060777340bb4a3 475 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 360 469 9.3E-28 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CFK41_RS01180 b8022c6a898b1ab0b13047bc69e4e71d 495 Gene3D G3DSA:3.30.420.40 248 495 1.1E-60 T 28-03-2018 CFK41_RS01180 b8022c6a898b1ab0b13047bc69e4e71d 495 SUPERFAMILY SSF53067 8 253 2.68E-52 T 28-03-2018 CFK41_RS01180 b8022c6a898b1ab0b13047bc69e4e71d 495 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 8 245 1.2E-40 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CFK41_RS01180 b8022c6a898b1ab0b13047bc69e4e71d 495 PIRSF PIRSF000538 5 491 9.8E-122 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CFK41_RS01180 b8022c6a898b1ab0b13047bc69e4e71d 495 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 260 440 3.2E-37 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CFK41_RS01180 b8022c6a898b1ab0b13047bc69e4e71d 495 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 355 375 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CFK41_RS01180 b8022c6a898b1ab0b13047bc69e4e71d 495 Gene3D G3DSA:3.30.420.40 2 247 3.0E-58 T 28-03-2018 CFK41_RS01180 b8022c6a898b1ab0b13047bc69e4e71d 495 SUPERFAMILY SSF53067 252 485 9.06E-60 T 28-03-2018 CFK41_RS09340 cf27736622dff76e6be2e2ea224f0ef4 498 SUPERFAMILY SSF50249 205 288 3.36E-27 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS09340 cf27736622dff76e6be2e2ea224f0ef4 498 Gene3D G3DSA:2.40.50.140 200 281 1.2E-27 T 28-03-2018 CFK41_RS09340 cf27736622dff76e6be2e2ea224f0ef4 498 SMART SM00316 32 103 6.2E-17 T 28-03-2018 IPR022967 RNA-binding domain, S1 CFK41_RS09340 cf27736622dff76e6be2e2ea224f0ef4 498 SMART SM00316 119 186 2.1E-11 T 28-03-2018 IPR022967 RNA-binding domain, S1 CFK41_RS09340 cf27736622dff76e6be2e2ea224f0ef4 498 SMART SM00316 290 361 5.6E-24 T 28-03-2018 IPR022967 RNA-binding domain, S1 CFK41_RS09340 cf27736622dff76e6be2e2ea224f0ef4 498 SMART SM00316 205 275 1.1E-27 T 28-03-2018 IPR022967 RNA-binding domain, S1 CFK41_RS09340 cf27736622dff76e6be2e2ea224f0ef4 498 SUPERFAMILY SSF50249 27 128 2.16E-21 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS09340 cf27736622dff76e6be2e2ea224f0ef4 498 SUPERFAMILY SSF50249 275 363 1.04E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS09340 cf27736622dff76e6be2e2ea224f0ef4 498 Pfam PF00575 S1 RNA binding domain 204 275 1.0E-25 T 28-03-2018 IPR003029 S1 domain GO:0003676 CFK41_RS09340 cf27736622dff76e6be2e2ea224f0ef4 498 Pfam PF00575 S1 RNA binding domain 122 186 5.5E-15 T 28-03-2018 IPR003029 S1 domain GO:0003676 CFK41_RS09340 cf27736622dff76e6be2e2ea224f0ef4 498 Pfam PF00575 S1 RNA binding domain 289 361 2.8E-21 T 28-03-2018 IPR003029 S1 domain GO:0003676 CFK41_RS09340 cf27736622dff76e6be2e2ea224f0ef4 498 Pfam PF00575 S1 RNA binding domain 31 103 7.5E-15 T 28-03-2018 IPR003029 S1 domain GO:0003676 CFK41_RS09340 cf27736622dff76e6be2e2ea224f0ef4 498 Gene3D G3DSA:2.40.50.140 12 108 2.3E-17 T 28-03-2018 CFK41_RS09340 cf27736622dff76e6be2e2ea224f0ef4 498 Gene3D G3DSA:2.40.50.140 122 193 2.0E-13 T 28-03-2018 CFK41_RS09340 cf27736622dff76e6be2e2ea224f0ef4 498 Gene3D G3DSA:2.40.50.140 292 451 6.3E-24 T 28-03-2018 CFK41_RS09340 cf27736622dff76e6be2e2ea224f0ef4 498 SUPERFAMILY SSF50249 123 199 3.58E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS09340 cf27736622dff76e6be2e2ea224f0ef4 498 PRINTS PR00681 Ribosomal protein S1 signature 170 190 5.1E-86 T 28-03-2018 CFK41_RS09340 cf27736622dff76e6be2e2ea224f0ef4 498 PRINTS PR00681 Ribosomal protein S1 signature 344 362 5.1E-86 T 28-03-2018 CFK41_RS09340 cf27736622dff76e6be2e2ea224f0ef4 498 PRINTS PR00681 Ribosomal protein S1 signature 100 119 5.1E-86 T 28-03-2018 CFK41_RS09340 cf27736622dff76e6be2e2ea224f0ef4 498 PRINTS PR00681 Ribosomal protein S1 signature 124 140 5.1E-86 T 28-03-2018 CFK41_RS09340 cf27736622dff76e6be2e2ea224f0ef4 498 PRINTS PR00681 Ribosomal protein S1 signature 305 324 5.1E-86 T 28-03-2018 CFK41_RS09340 cf27736622dff76e6be2e2ea224f0ef4 498 PRINTS PR00681 Ribosomal protein S1 signature 227 248 5.1E-86 T 28-03-2018 CFK41_RS09340 cf27736622dff76e6be2e2ea224f0ef4 498 PRINTS PR00681 Ribosomal protein S1 signature 141 158 5.1E-86 T 28-03-2018 CFK41_RS09340 cf27736622dff76e6be2e2ea224f0ef4 498 PRINTS PR00681 Ribosomal protein S1 signature 52 66 5.1E-86 T 28-03-2018 CFK41_RS09340 cf27736622dff76e6be2e2ea224f0ef4 498 PRINTS PR00681 Ribosomal protein S1 signature 34 52 5.1E-86 T 28-03-2018 CFK41_RS14170 bf72d6f92c0bebe7f72e66d55cad34aa 318 SUPERFAMILY SSF161098 80 307 2.22E-57 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS14170 bf72d6f92c0bebe7f72e66d55cad34aa 318 Gene3D G3DSA:1.10.3720.10 87 316 2.7E-37 T 28-03-2018 CFK41_RS14170 bf72d6f92c0bebe7f72e66d55cad34aa 318 Gene3D G3DSA:1.20.58.370 28 69 9.8E-7 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CFK41_RS14170 bf72d6f92c0bebe7f72e66d55cad34aa 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 316 7.3E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS08555 c722972bd6f9655d1ee1bef67c934749 467 Gene3D G3DSA:1.20.272.10 275 360 2.3E-39 T 28-03-2018 CFK41_RS08555 c722972bd6f9655d1ee1bef67c934749 467 Gene3D G3DSA:3.40.50.300 17 171 3.2E-25 T 28-03-2018 CFK41_RS08555 c722972bd6f9655d1ee1bef67c934749 467 SMART SM00382 66 182 1.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS08555 c722972bd6f9655d1ee1bef67c934749 467 SUPERFAMILY SSF52540 24 250 2.61E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS08555 c722972bd6f9655d1ee1bef67c934749 467 Gene3D G3DSA:1.10.3710.10 363 455 1.5E-30 T 28-03-2018 CFK41_RS08555 c722972bd6f9655d1ee1bef67c934749 467 Pfam PF16193 AAA C-terminal domain 205 281 1.2E-25 T 28-03-2018 IPR032423 AAA C-terminal domain CFK41_RS08555 c722972bd6f9655d1ee1bef67c934749 467 Gene3D G3DSA:1.10.8.60 172 274 1.7E-17 T 28-03-2018 CFK41_RS08555 c722972bd6f9655d1ee1bef67c934749 467 SUPERFAMILY SSF48019 267 450 8.5E-75 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CFK41_RS08555 c722972bd6f9655d1ee1bef67c934749 467 Pfam PF12002 MgsA AAA+ ATPase C terminal 282 447 3.9E-70 T 28-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal CFK41_RS08555 c722972bd6f9655d1ee1bef67c934749 467 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 22 155 3.9E-15 T 28-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CFK41_RS00565 f8f64387028ae1ac59839aa10f891770 360 Gene3D G3DSA:1.10.260.40 21 59 1.8E-18 T 28-03-2018 CFK41_RS00565 f8f64387028ae1ac59839aa10f891770 360 Pfam PF13377 Periplasmic binding protein-like domain 174 318 6.0E-20 T 28-03-2018 CFK41_RS00565 f8f64387028ae1ac59839aa10f891770 360 SUPERFAMILY SSF53822 65 312 3.0E-29 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS00565 f8f64387028ae1ac59839aa10f891770 360 Gene3D G3DSA:3.40.50.2300 178 319 1.3E-22 T 28-03-2018 CFK41_RS00565 f8f64387028ae1ac59839aa10f891770 360 SUPERFAMILY SSF47413 4 61 6.57E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS00565 f8f64387028ae1ac59839aa10f891770 360 Gene3D G3DSA:3.40.50.2300 60 177 6.7E-20 T 28-03-2018 CFK41_RS00565 f8f64387028ae1ac59839aa10f891770 360 Gene3D G3DSA:1.10.10.60 5 20 4.5E-5 T 28-03-2018 CFK41_RS00565 f8f64387028ae1ac59839aa10f891770 360 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 52 1.1E-13 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS00565 f8f64387028ae1ac59839aa10f891770 360 SMART SM00354 4 75 6.8E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS07195 2173e1d4a0110aece5f44bc9d74817e3 273 SUPERFAMILY SSF55729 133 263 1.44E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS07195 2173e1d4a0110aece5f44bc9d74817e3 273 Gene3D G3DSA:3.40.630.30 29 272 7.6E-22 T 28-03-2018 CFK41_RS07195 2173e1d4a0110aece5f44bc9d74817e3 273 Pfam PF00583 Acetyltransferase (GNAT) family 188 255 9.8E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS05425 b5bdd295c0dccfcc70480f03d2d1d9d7 489 Gene3D G3DSA:1.20.1250.20 23 250 2.7E-13 T 28-03-2018 CFK41_RS05425 b5bdd295c0dccfcc70480f03d2d1d9d7 489 SUPERFAMILY SSF103473 34 471 4.71E-35 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS05425 b5bdd295c0dccfcc70480f03d2d1d9d7 489 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 33 478 1.1E-95 T 28-03-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 CFK41_RS05425 b5bdd295c0dccfcc70480f03d2d1d9d7 489 Pfam PF13347 MFS/sugar transport protein 35 465 1.8E-93 T 28-03-2018 CFK41_RS05425 b5bdd295c0dccfcc70480f03d2d1d9d7 489 Gene3D G3DSA:1.20.1250.20 252 474 2.8E-23 T 28-03-2018 CFK41_RS14165 2a88651bf5702873da1e5260698d7579 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 279 3.9E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS14165 2a88651bf5702873da1e5260698d7579 288 Gene3D G3DSA:1.10.3720.10 12 275 5.8E-43 T 28-03-2018 CFK41_RS14165 2a88651bf5702873da1e5260698d7579 288 SUPERFAMILY SSF161098 15 288 6.41E-64 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS13125 92f35f915932134d02a2cfaf9a8e6c0d 225 Gene3D G3DSA:3.40.470.10 2 224 7.6E-75 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CFK41_RS13125 92f35f915932134d02a2cfaf9a8e6c0d 225 SMART SM00986 52 211 6.5E-27 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CFK41_RS13125 92f35f915932134d02a2cfaf9a8e6c0d 225 SMART SM00987 52 211 6.5E-27 T 28-03-2018 CFK41_RS13125 92f35f915932134d02a2cfaf9a8e6c0d 225 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 10 222 32.808 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CFK41_RS13125 92f35f915932134d02a2cfaf9a8e6c0d 225 Pfam PF03167 Uracil DNA glycosylase superfamily 57 210 2.0E-17 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CFK41_RS13125 92f35f915932134d02a2cfaf9a8e6c0d 225 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 60 69 - T 28-03-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CFK41_RS13125 92f35f915932134d02a2cfaf9a8e6c0d 225 SUPERFAMILY SSF52141 8 222 1.06E-68 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CFK41_RS15965 ce6af102379353c96e916492b7bc759c 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 123 297 6.4E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS15965 ce6af102379353c96e916492b7bc759c 304 SUPERFAMILY SSF161098 25 304 1.4E-50 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS15965 ce6af102379353c96e916492b7bc759c 304 Gene3D G3DSA:1.10.3720.10 81 299 2.0E-30 T 28-03-2018 CFK41_RS07915 91eff23c0f01fe30465988aaef626cf9 517 Gene3D G3DSA:3.65.10.10 100 302 1.5E-25 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CFK41_RS07915 91eff23c0f01fe30465988aaef626cf9 517 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 86 501 8.8E-43 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CFK41_RS07915 91eff23c0f01fe30465988aaef626cf9 517 SUPERFAMILY SSF47413 10 73 8.16E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS07915 91eff23c0f01fe30465988aaef626cf9 517 Gene3D G3DSA:3.65.10.10 303 516 4.2E-34 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CFK41_RS07915 91eff23c0f01fe30465988aaef626cf9 517 SMART SM00530 20 75 1.2E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CFK41_RS07915 91eff23c0f01fe30465988aaef626cf9 517 Gene3D G3DSA:3.30.1190.10 41 91 7.4E-12 T 28-03-2018 CFK41_RS07915 91eff23c0f01fe30465988aaef626cf9 517 Pfam PF01381 Helix-turn-helix 21 72 3.5E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CFK41_RS07915 91eff23c0f01fe30465988aaef626cf9 517 SUPERFAMILY SSF55205 82 514 1.8E-93 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CFK41_RS07915 91eff23c0f01fe30465988aaef626cf9 517 Gene3D G3DSA:1.10.10.60 6 40 1.7E-7 T 28-03-2018 CFK41_RS03110 adfc7dcddd793d726716219fca63f01b 459 Pfam PF02447 GntP family permease 16 455 1.3E-122 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CFK41_RS03110 adfc7dcddd793d726716219fca63f01b 459 PIRSF PIRSF002746 10 459 2.7E-144 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CFK41_RS03110 adfc7dcddd793d726716219fca63f01b 459 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 16 457 1.6E-111 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CFK41_RS08905 b73618931c3b53d1237aae06218a3f12 222 Gene3D G3DSA:1.10.357.10 71 221 2.5E-11 T 28-03-2018 CFK41_RS08905 b73618931c3b53d1237aae06218a3f12 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 70 9.5E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS08905 b73618931c3b53d1237aae06218a3f12 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 2.0E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS08905 b73618931c3b53d1237aae06218a3f12 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 2.0E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS08905 b73618931c3b53d1237aae06218a3f12 222 Gene3D G3DSA:1.10.10.60 14 70 2.0E-19 T 28-03-2018 CFK41_RS08905 b73618931c3b53d1237aae06218a3f12 222 SUPERFAMILY SSF46689 14 83 2.46E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS01350 0b79313f3bb440829a9fc1900b764ce1 435 Gene3D G3DSA:3.40.190.10 294 379 3.1E-4 T 28-03-2018 CFK41_RS01350 0b79313f3bb440829a9fc1900b764ce1 435 SUPERFAMILY SSF53850 37 428 1.24E-46 T 28-03-2018 CFK41_RS01350 0b79313f3bb440829a9fc1900b764ce1 435 Pfam PF13416 Bacterial extracellular solute-binding protein 56 361 8.8E-28 T 28-03-2018 CFK41_RS01350 0b79313f3bb440829a9fc1900b764ce1 435 Gene3D G3DSA:3.40.190.10 27 219 1.1E-31 T 28-03-2018 CFK41_RS15770 acb28ba1dda4fbef1fa791cc5c1331e0 1125 Gene3D G3DSA:3.30.2090.10 736 821 1.0E-11 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CFK41_RS15770 acb28ba1dda4fbef1fa791cc5c1331e0 1125 Gene3D G3DSA:3.30.2090.10 178 287 7.1E-14 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CFK41_RS15770 acb28ba1dda4fbef1fa791cc5c1331e0 1125 SUPERFAMILY SSF82866 816 1039 1.83E-47 T 28-03-2018 CFK41_RS15770 acb28ba1dda4fbef1fa791cc5c1331e0 1125 Gene3D G3DSA:1.20.1640.10 301 521 9.8E-45 T 28-03-2018 CFK41_RS15770 acb28ba1dda4fbef1fa791cc5c1331e0 1125 Gene3D G3DSA:1.20.1640.10 830 1052 1.9E-41 T 28-03-2018 CFK41_RS15770 acb28ba1dda4fbef1fa791cc5c1331e0 1125 SUPERFAMILY SSF82866 313 512 1.96E-43 T 28-03-2018 CFK41_RS15770 acb28ba1dda4fbef1fa791cc5c1331e0 1125 SUPERFAMILY SSF82714 183 250 2.09E-8 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CFK41_RS15770 acb28ba1dda4fbef1fa791cc5c1331e0 1125 Gene3D G3DSA:3.30.70.1430 593 731 8.2E-10 T 28-03-2018 CFK41_RS15770 acb28ba1dda4fbef1fa791cc5c1331e0 1125 Gene3D G3DSA:3.30.70.1430 41 142 8.9E-23 T 28-03-2018 CFK41_RS15770 acb28ba1dda4fbef1fa791cc5c1331e0 1125 SUPERFAMILY SSF82693 41 130 5.06E-21 T 28-03-2018 CFK41_RS15770 acb28ba1dda4fbef1fa791cc5c1331e0 1125 PRINTS PR00702 Acriflavin resistance protein family signature 484 507 1.1E-38 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CFK41_RS15770 acb28ba1dda4fbef1fa791cc5c1331e0 1125 PRINTS PR00702 Acriflavin resistance protein family signature 378 399 1.1E-38 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CFK41_RS15770 acb28ba1dda4fbef1fa791cc5c1331e0 1125 PRINTS PR00702 Acriflavin resistance protein family signature 406 430 1.1E-38 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CFK41_RS15770 acb28ba1dda4fbef1fa791cc5c1331e0 1125 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 1.1E-38 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CFK41_RS15770 acb28ba1dda4fbef1fa791cc5c1331e0 1125 PRINTS PR00702 Acriflavin resistance protein family signature 351 374 1.1E-38 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CFK41_RS15770 acb28ba1dda4fbef1fa791cc5c1331e0 1125 PRINTS PR00702 Acriflavin resistance protein family signature 459 482 1.1E-38 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CFK41_RS15770 acb28ba1dda4fbef1fa791cc5c1331e0 1125 SUPERFAMILY SSF82693 289 344 1.26E-12 T 28-03-2018 CFK41_RS15770 acb28ba1dda4fbef1fa791cc5c1331e0 1125 SUPERFAMILY SSF82693 135 180 1.26E-12 T 28-03-2018 CFK41_RS15770 acb28ba1dda4fbef1fa791cc5c1331e0 1125 SUPERFAMILY SSF82714 738 817 1.7E-8 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CFK41_RS15770 acb28ba1dda4fbef1fa791cc5c1331e0 1125 Pfam PF00873 AcrB/AcrD/AcrF family 5 1038 5.1E-202 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CFK41_RS11020 f61fa9081942b5a472b6b66d9b463cf7 269 Pfam PF02585 GlcNAc-PI de-N-acetylase 26 189 2.1E-24 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CFK41_RS11020 f61fa9081942b5a472b6b66d9b463cf7 269 SUPERFAMILY SSF102588 23 240 8.89E-42 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CFK41_RS11020 f61fa9081942b5a472b6b66d9b463cf7 269 Gene3D G3DSA:3.40.50.10320 19 261 1.0E-45 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CFK41_RS11785 5ad96d20c7986eb3322a4720124e9fc9 278 Gene3D G3DSA:3.40.50.150 42 276 4.0E-29 T 28-03-2018 CFK41_RS11785 5ad96d20c7986eb3322a4720124e9fc9 278 SUPERFAMILY SSF53335 41 257 4.85E-31 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS11785 5ad96d20c7986eb3322a4720124e9fc9 278 Pfam PF13649 Methyltransferase domain 58 153 1.0E-12 T 28-03-2018 CFK41_RS02195 abd776fc12c21133fbe44bc2eaf484c1 297 Gene3D G3DSA:1.10.3720.10 19 285 5.3E-41 T 28-03-2018 CFK41_RS02195 abd776fc12c21133fbe44bc2eaf484c1 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 291 3.6E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS02195 abd776fc12c21133fbe44bc2eaf484c1 297 SUPERFAMILY SSF161098 22 290 4.32E-61 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS13995 cd972c3bc6ae94b8fcb744314774e51a 582 SUPERFAMILY SSF51445 36 418 4.42E-101 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS13995 cd972c3bc6ae94b8fcb744314774e51a 582 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 420 570 1.6E-9 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CFK41_RS13995 cd972c3bc6ae94b8fcb744314774e51a 582 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 303 320 - T 28-03-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 CFK41_RS13995 cd972c3bc6ae94b8fcb744314774e51a 582 PRINTS PR00133 Glycosyl hydrolase family 3 signature 303 321 1.6E-5 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS13995 cd972c3bc6ae94b8fcb744314774e51a 582 PRINTS PR00133 Glycosyl hydrolase family 3 signature 122 138 1.6E-5 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS13995 cd972c3bc6ae94b8fcb744314774e51a 582 PRINTS PR00133 Glycosyl hydrolase family 3 signature 226 242 1.6E-5 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS13995 cd972c3bc6ae94b8fcb744314774e51a 582 PRINTS PR00133 Glycosyl hydrolase family 3 signature 148 167 1.6E-5 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS13995 cd972c3bc6ae94b8fcb744314774e51a 582 SUPERFAMILY SSF52279 420 581 1.83E-10 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CFK41_RS13995 cd972c3bc6ae94b8fcb744314774e51a 582 Gene3D G3DSA:3.40.50.1700 457 580 3.7E-10 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CFK41_RS13995 cd972c3bc6ae94b8fcb744314774e51a 582 Gene3D G3DSA:3.40.50.1700 408 456 0.081 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CFK41_RS13995 cd972c3bc6ae94b8fcb744314774e51a 582 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 47 380 4.9E-105 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS13995 cd972c3bc6ae94b8fcb744314774e51a 582 Gene3D G3DSA:3.20.20.300 32 407 2.1E-104 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS05550 03b4d75812a647488283d02fe2a6185e 820 SUPERFAMILY SSF52518 389 605 7.65E-25 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CFK41_RS05550 03b4d75812a647488283d02fe2a6185e 820 SUPERFAMILY SSF52518 16 381 1.26E-60 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CFK41_RS05550 03b4d75812a647488283d02fe2a6185e 820 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 412 588 5.3E-91 T 28-03-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 CFK41_RS05550 03b4d75812a647488283d02fe2a6185e 820 Gene3D G3DSA:3.40.50.920 619 803 2.5E-77 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CFK41_RS05550 03b4d75812a647488283d02fe2a6185e 820 Hamap MF_01403 Probable phosphoketolase. 10 803 39.872 T 28-03-2018 IPR023962 Probable phosphoketolase CFK41_RS05550 03b4d75812a647488283d02fe2a6185e 820 ProSitePatterns PS60003 Phosphoketolase signature 2. 162 180 - T 28-03-2018 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 CFK41_RS05550 03b4d75812a647488283d02fe2a6185e 820 Pfam PF09363 XFP C-terminal domain 599 801 9.2E-87 T 28-03-2018 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 CFK41_RS05550 03b4d75812a647488283d02fe2a6185e 820 Gene3D G3DSA:3.40.50.970 7 391 1.4E-86 T 28-03-2018 CFK41_RS05550 03b4d75812a647488283d02fe2a6185e 820 ProSitePatterns PS60002 Phosphoketolase signature 1. 149 155 - T 28-03-2018 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 CFK41_RS05550 03b4d75812a647488283d02fe2a6185e 820 PIRSF PIRSF017245 7 803 0.0 T 28-03-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 CFK41_RS05550 03b4d75812a647488283d02fe2a6185e 820 Gene3D G3DSA:3.40.50.970 399 613 2.2E-36 T 28-03-2018 CFK41_RS05550 03b4d75812a647488283d02fe2a6185e 820 Pfam PF09364 XFP N-terminal domain 14 398 7.6E-182 T 28-03-2018 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal CFK41_RS05550 03b4d75812a647488283d02fe2a6185e 820 SUPERFAMILY SSF52922 619 754 1.15E-6 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CFK41_RS12650 4c11515943d903a24de89251c30601fd 417 Pfam PF03453 MoeA N-terminal region (domain I and II) 10 177 6.1E-38 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CFK41_RS12650 4c11515943d903a24de89251c30601fd 417 Gene3D G3DSA:2.40.340.10 343 413 1.8E-11 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CFK41_RS12650 4c11515943d903a24de89251c30601fd 417 SUPERFAMILY SSF63882 7 183 1.31E-36 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CFK41_RS12650 4c11515943d903a24de89251c30601fd 417 Gene3D G3DSA:3.40.980.10 160 342 1.9E-40 T 28-03-2018 IPR001453 MoaB/Mog domain CFK41_RS12650 4c11515943d903a24de89251c30601fd 417 SUPERFAMILY SSF63867 344 412 1.26E-8 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CFK41_RS12650 4c11515943d903a24de89251c30601fd 417 SMART SM00852 190 335 3.9E-28 T 28-03-2018 IPR001453 MoaB/Mog domain CFK41_RS12650 4c11515943d903a24de89251c30601fd 417 SUPERFAMILY SSF53218 188 335 7.46E-29 T 28-03-2018 IPR001453 MoaB/Mog domain CFK41_RS12650 4c11515943d903a24de89251c30601fd 417 Gene3D G3DSA:3.90.105.10 26 61 4.6E-7 T 28-03-2018 CFK41_RS12650 4c11515943d903a24de89251c30601fd 417 Gene3D G3DSA:2.170.190.11 62 151 1.0E-22 T 28-03-2018 CFK41_RS12650 4c11515943d903a24de89251c30601fd 417 Pfam PF00994 Probable molybdopterin binding domain 191 333 2.7E-20 T 28-03-2018 IPR001453 MoaB/Mog domain CFK41_RS12650 4c11515943d903a24de89251c30601fd 417 Pfam PF03454 MoeA C-terminal region (domain IV) 348 411 1.3E-5 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CFK41_RS13305 2971e2bea6157ea72d22659babf14369 259 Gene3D G3DSA:1.10.3720.10 19 230 5.3E-33 T 28-03-2018 CFK41_RS13305 2971e2bea6157ea72d22659babf14369 259 TIGRFAM TIGR03004 ectoine_ehuC: ectoine/hydroxyectoine ABC transporter, permease protein EhuC 21 226 9.7E-61 T 28-03-2018 IPR014342 Ectoine/hydroxyectoine ABC transporter, permease protein EhuC CFK41_RS13305 2971e2bea6157ea72d22659babf14369 259 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 22 123 3.2E-23 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CFK41_RS13305 2971e2bea6157ea72d22659babf14369 259 SUPERFAMILY SSF161098 23 214 1.01E-33 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS13305 2971e2bea6157ea72d22659babf14369 259 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 52 224 2.2E-11 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01715 c07e6c064b4aa31ab83e9ca063f7d052 524 SUPERFAMILY SSF75005 5 281 1.83E-73 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CFK41_RS01715 c07e6c064b4aa31ab83e9ca063f7d052 524 Pfam PF04616 Glycosyl hydrolases family 43 5 277 1.4E-64 T 28-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 CFK41_RS01715 c07e6c064b4aa31ab83e9ca063f7d052 524 SUPERFAMILY SSF49899 312 496 3.56E-14 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CFK41_RS01715 c07e6c064b4aa31ab83e9ca063f7d052 524 Gene3D G3DSA:2.115.10.20 2 287 5.3E-57 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CFK41_RS01715 c07e6c064b4aa31ab83e9ca063f7d052 524 Gene3D G3DSA:2.60.120.200 307 504 9.4E-25 T 28-03-2018 CFK41_RS13585 7c9a148ef231c053565e89e67b437f8f 278 SMART SM00382 35 228 1.5E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS13585 7c9a148ef231c053565e89e67b437f8f 278 SUPERFAMILY SSF52540 10 243 3.7E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS13585 7c9a148ef231c053565e89e67b437f8f 278 Pfam PF00005 ABC transporter 27 179 1.9E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS13585 7c9a148ef231c053565e89e67b437f8f 278 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS13585 7c9a148ef231c053565e89e67b437f8f 278 Gene3D G3DSA:3.40.50.300 2 249 9.3E-55 T 28-03-2018 CFK41_RS01925 60db146c5be837ba6e7a07f268b8e718 450 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 57 446 2.2E-79 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CFK41_RS01925 60db146c5be837ba6e7a07f268b8e718 450 Pfam PF00579 tRNA synthetases class I (W and Y) 79 359 1.2E-45 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS01925 60db146c5be837ba6e7a07f268b8e718 450 SUPERFAMILY SSF52374 53 366 9.25E-59 T 28-03-2018 CFK41_RS01925 60db146c5be837ba6e7a07f268b8e718 450 SUPERFAMILY SSF55174 372 445 3.66E-9 T 28-03-2018 CFK41_RS01925 60db146c5be837ba6e7a07f268b8e718 450 Gene3D G3DSA:1.10.240.10 271 360 4.0E-10 T 28-03-2018 CFK41_RS01925 60db146c5be837ba6e7a07f268b8e718 450 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 261 273 1.2E-13 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CFK41_RS01925 60db146c5be837ba6e7a07f268b8e718 450 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 94 116 1.2E-13 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CFK41_RS01925 60db146c5be837ba6e7a07f268b8e718 450 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 211 226 1.2E-13 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CFK41_RS01925 60db146c5be837ba6e7a07f268b8e718 450 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 228 250 1.2E-13 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CFK41_RS01925 60db146c5be837ba6e7a07f268b8e718 450 Gene3D G3DSA:3.10.290.10 361 449 8.0E-9 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CFK41_RS01925 60db146c5be837ba6e7a07f268b8e718 450 Gene3D G3DSA:3.40.50.620 50 267 5.2E-45 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS03395 c074cb6313092c823211c7fa68f45aff 166 SUPERFAMILY SSF55298 9 158 1.16E-54 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CFK41_RS03395 c074cb6313092c823211c7fa68f45aff 166 Gene3D G3DSA:3.30.1330.40 3 160 7.6E-32 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CFK41_RS03395 c074cb6313092c823211c7fa68f45aff 166 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 12 158 3.6E-35 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CFK41_RS06395 413e3e3a1d6684bd2d5162371c03a656 421 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 137 190 1.0E-8 T 28-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 CFK41_RS06395 413e3e3a1d6684bd2d5162371c03a656 421 Gene3D G3DSA:3.40.50.300 132 389 1.1E-33 T 28-03-2018 CFK41_RS06395 413e3e3a1d6684bd2d5162371c03a656 421 SUPERFAMILY SSF52540 135 387 6.27E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS17060 618c944537bc7ccde0acc3964bc0bd31 394 Pfam PF13378 Enolase C-terminal domain-like 179 385 3.0E-47 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS17060 618c944537bc7ccde0acc3964bc0bd31 394 SUPERFAMILY SSF51604 139 392 8.91E-64 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS17060 618c944537bc7ccde0acc3964bc0bd31 394 SMART SM00922 167 263 8.3E-8 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CFK41_RS17060 618c944537bc7ccde0acc3964bc0bd31 394 SUPERFAMILY SSF54826 49 156 1.18E-25 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS17060 618c944537bc7ccde0acc3964bc0bd31 394 Gene3D G3DSA:3.20.20.120 154 383 2.8E-52 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS17060 618c944537bc7ccde0acc3964bc0bd31 394 Hamap MF_01288 L-rhamnonate dehydratase [rhmD]. 3 394 75.628 T 28-03-2018 IPR023444 L-rhamnonate dehydratase GO:0050032 KEGG: 00051+4.2.1.90|MetaCyc: PWY-6713|MetaCyc: PWY-6714 CFK41_RS17060 618c944537bc7ccde0acc3964bc0bd31 394 Gene3D G3DSA:3.30.390.10 1 153 1.2E-51 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS17060 618c944537bc7ccde0acc3964bc0bd31 394 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 126 151 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CFK41_RS17060 618c944537bc7ccde0acc3964bc0bd31 394 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 62 151 5.2E-10 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CFK41_RS17275 ac0079878429b546fbf6107ac0038c0f 212 SUPERFAMILY SSF52172 1 140 1.71E-30 T 28-03-2018 IPR011006 CheY-like superfamily CFK41_RS17275 ac0079878429b546fbf6107ac0038c0f 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 205 1.1E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS17275 ac0079878429b546fbf6107ac0038c0f 212 ProSitePatterns PS00622 LuxR-type HTH domain signature. 165 192 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS17275 ac0079878429b546fbf6107ac0038c0f 212 SMART SM00421 148 205 3.2E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS17275 ac0079878429b546fbf6107ac0038c0f 212 Pfam PF00072 Response regulator receiver domain 5 123 2.0E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS17275 ac0079878429b546fbf6107ac0038c0f 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 6.8E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS17275 ac0079878429b546fbf6107ac0038c0f 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 6.8E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS17275 ac0079878429b546fbf6107ac0038c0f 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 6.8E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS17275 ac0079878429b546fbf6107ac0038c0f 212 SMART SM00448 3 122 2.1E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS17275 ac0079878429b546fbf6107ac0038c0f 212 Gene3D G3DSA:3.40.50.2300 2 133 3.6E-35 T 28-03-2018 CFK41_RS17275 ac0079878429b546fbf6107ac0038c0f 212 Gene3D G3DSA:1.10.10.10 134 212 1.6E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS17275 ac0079878429b546fbf6107ac0038c0f 212 SUPERFAMILY SSF46894 138 211 3.74E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CFK41_RS09085 d69e664feab612b8b726faffece65928 458 Gene3D G3DSA:3.40.605.10 1 244 5.9E-75 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CFK41_RS09085 d69e664feab612b8b726faffece65928 458 Gene3D G3DSA:3.40.309.10 245 437 4.7E-65 T 28-03-2018 CFK41_RS09085 d69e664feab612b8b726faffece65928 458 SUPERFAMILY SSF53720 3 454 4.84E-142 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CFK41_RS09085 d69e664feab612b8b726faffece65928 458 Pfam PF00171 Aldehyde dehydrogenase family 4 451 3.5E-140 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CFK41_RS17245 a6c6fc0b6699c454d8a73208fd5b4d9d 303 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 18 303 2.0E-142 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CFK41_RS17245 a6c6fc0b6699c454d8a73208fd5b4d9d 303 ProSitePatterns PS01235 PdxS/SNZ family signature. 214 232 - T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CFK41_RS17245 a6c6fc0b6699c454d8a73208fd5b4d9d 303 PIRSF PIRSF029271 4 303 4.5E-149 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CFK41_RS17245 a6c6fc0b6699c454d8a73208fd5b4d9d 303 SUPERFAMILY SSF51366 27 274 5.65E-60 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CFK41_RS17245 a6c6fc0b6699c454d8a73208fd5b4d9d 303 Pfam PF01680 SOR/SNZ family 17 221 5.7E-105 T 28-03-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CFK41_RS17245 a6c6fc0b6699c454d8a73208fd5b4d9d 303 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 13 303 51.994 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CFK41_RS17245 a6c6fc0b6699c454d8a73208fd5b4d9d 303 Gene3D G3DSA:3.20.20.70 27 280 9.1E-66 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS17455 b7a92d8961166f9229315433d67e8dcc 351 Pfam PF01872 RibD C-terminal domain 156 328 1.1E-39 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CFK41_RS17455 b7a92d8961166f9229315433d67e8dcc 351 Gene3D G3DSA:3.40.430.10 247 348 2.4E-22 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CFK41_RS17455 b7a92d8961166f9229315433d67e8dcc 351 SUPERFAMILY SSF53927 9 138 1.42E-35 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CFK41_RS17455 b7a92d8961166f9229315433d67e8dcc 351 Gene3D G3DSA:3.40.140.10 6 129 1.1E-25 T 28-03-2018 CFK41_RS17455 b7a92d8961166f9229315433d67e8dcc 351 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 26 106 4.3E-15 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CFK41_RS17455 b7a92d8961166f9229315433d67e8dcc 351 SUPERFAMILY SSF53597 154 333 1.54E-45 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CFK41_RS17455 b7a92d8961166f9229315433d67e8dcc 351 Gene3D G3DSA:3.40.430.10 130 246 1.1E-30 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CFK41_RS17455 b7a92d8961166f9229315433d67e8dcc 351 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 11 326 3.4E-82 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CFK41_RS17455 b7a92d8961166f9229315433d67e8dcc 351 PIRSF PIRSF006769 1 244 4.3E-82 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CFK41_RS17455 b7a92d8961166f9229315433d67e8dcc 351 PIRSF PIRSF006769 246 332 3.2E-13 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CFK41_RS17455 b7a92d8961166f9229315433d67e8dcc 351 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 54 95 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CFK41_RS11965 69e6a38e315fb90c43b43640c67b3487 509 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 226 508 57.338 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CFK41_RS11965 69e6a38e315fb90c43b43640c67b3487 509 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 227 507 3.0E-101 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CFK41_RS11965 69e6a38e315fb90c43b43640c67b3487 509 SMART SM00382 304 459 1.5E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS11965 69e6a38e315fb90c43b43640c67b3487 509 SUPERFAMILY SSF52540 303 508 7.69E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11965 69e6a38e315fb90c43b43640c67b3487 509 Gene3D G3DSA:1.20.120.140 228 307 1.3E-15 T 28-03-2018 CFK41_RS11965 69e6a38e315fb90c43b43640c67b3487 509 Pfam PF02881 SRP54-type protein, helical bundle domain 213 279 3.8E-12 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CFK41_RS11965 69e6a38e315fb90c43b43640c67b3487 509 SMART SM00962 305 508 3.8E-102 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CFK41_RS11965 69e6a38e315fb90c43b43640c67b3487 509 SUPERFAMILY SSF47364 210 285 4.97E-14 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CFK41_RS11965 69e6a38e315fb90c43b43640c67b3487 509 Pfam PF00448 SRP54-type protein, GTPase domain 305 507 2.1E-73 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CFK41_RS11965 69e6a38e315fb90c43b43640c67b3487 509 SMART SM00963 203 283 1.1E-18 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CFK41_RS11965 69e6a38e315fb90c43b43640c67b3487 509 Gene3D G3DSA:3.40.50.300 308 509 2.0E-37 T 28-03-2018 CFK41_RS01790 1a8eaed15b43e1492dbf85f1907c278e 279 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 259 275 1.2E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CFK41_RS01790 1a8eaed15b43e1492dbf85f1907c278e 279 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 244 259 1.2E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CFK41_RS01790 1a8eaed15b43e1492dbf85f1907c278e 279 Gene3D G3DSA:1.10.10.60 230 279 1.1E-15 T 28-03-2018 CFK41_RS01790 1a8eaed15b43e1492dbf85f1907c278e 279 SMART SM00342 192 275 7.5E-28 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CFK41_RS01790 1a8eaed15b43e1492dbf85f1907c278e 279 SUPERFAMILY SSF51215 34 144 1.44E-14 T 28-03-2018 CFK41_RS01790 1a8eaed15b43e1492dbf85f1907c278e 279 Pfam PF02311 AraC-like ligand binding domain 40 117 3.0E-12 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CFK41_RS01790 1a8eaed15b43e1492dbf85f1907c278e 279 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 229 271 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CFK41_RS01790 1a8eaed15b43e1492dbf85f1907c278e 279 Pfam PF12833 Helix-turn-helix domain 198 277 1.4E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CFK41_RS01790 1a8eaed15b43e1492dbf85f1907c278e 279 SUPERFAMILY SSF46689 175 225 3.49E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS01790 1a8eaed15b43e1492dbf85f1907c278e 279 SUPERFAMILY SSF46689 229 278 1.75E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS01790 1a8eaed15b43e1492dbf85f1907c278e 279 Gene3D G3DSA:1.10.10.60 176 229 5.9E-10 T 28-03-2018 CFK41_RS01790 1a8eaed15b43e1492dbf85f1907c278e 279 Gene3D G3DSA:2.60.120.10 1 175 1.8E-5 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CFK41_RS13440 5dd0814d2a4186845a5b3612dea97d9a 572 SUPERFAMILY SSF52009 124 239 8.89E-26 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CFK41_RS13440 5dd0814d2a4186845a5b3612dea97d9a 572 Gene3D G3DSA:1.10.274.10 30 142 7.7E-23 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CFK41_RS13440 5dd0814d2a4186845a5b3612dea97d9a 572 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 256 534 6.8E-76 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CFK41_RS13440 5dd0814d2a4186845a5b3612dea97d9a 572 SUPERFAMILY SSF51621 256 536 7.42E-79 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CFK41_RS13440 5dd0814d2a4186845a5b3612dea97d9a 572 Pfam PF05524 PEP-utilising enzyme, N-terminal 5 125 8.7E-21 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CFK41_RS13440 5dd0814d2a4186845a5b3612dea97d9a 572 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 48 558 9.5E-109 T 28-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 CFK41_RS13440 5dd0814d2a4186845a5b3612dea97d9a 572 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 287 306 2.0E-16 T 28-03-2018 CFK41_RS13440 5dd0814d2a4186845a5b3612dea97d9a 572 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 448 463 2.0E-16 T 28-03-2018 CFK41_RS13440 5dd0814d2a4186845a5b3612dea97d9a 572 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 431 446 2.0E-16 T 28-03-2018 CFK41_RS13440 5dd0814d2a4186845a5b3612dea97d9a 572 Gene3D G3DSA:3.20.20.60 272 307 1.8E-13 T 28-03-2018 CFK41_RS13440 5dd0814d2a4186845a5b3612dea97d9a 572 Pfam PF00391 PEP-utilising enzyme, mobile domain 151 222 4.4E-17 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CFK41_RS13440 5dd0814d2a4186845a5b3612dea97d9a 572 SUPERFAMILY SSF47831 34 142 3.01E-20 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CFK41_RS13440 5dd0814d2a4186845a5b3612dea97d9a 572 Gene3D G3DSA:3.50.30.10 143 271 1.6E-19 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CFK41_RS13440 5dd0814d2a4186845a5b3612dea97d9a 572 PIRSF PIRSF000732 1 565 1.8E-145 T 28-03-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 CFK41_RS13440 5dd0814d2a4186845a5b3612dea97d9a 572 Gene3D G3DSA:3.20.20.60 308 538 1.2E-65 T 28-03-2018 CFK41_RS07445 5dfd3cb0eacd5daec2ab7128fbe23a5a 114 Gene3D G3DSA:3.10.180.10 1 111 1.7E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS07445 5dfd3cb0eacd5daec2ab7128fbe23a5a 114 SUPERFAMILY SSF54593 3 108 3.81E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS14260 ee2489c98e689353cbcf5104949640e2 281 PIRSF PIRSF006241 11 278 6.9E-60 T 28-03-2018 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 CFK41_RS14260 ee2489c98e689353cbcf5104949640e2 281 SUPERFAMILY SSF51658 13 271 2.09E-57 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS14260 ee2489c98e689353cbcf5104949640e2 281 Gene3D G3DSA:3.20.20.150 11 277 2.8E-50 T 28-03-2018 CFK41_RS14260 ee2489c98e689353cbcf5104949640e2 281 Pfam PF01261 Xylose isomerase-like TIM barrel 30 234 1.7E-23 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS12915 004c1487717966ec089f3f26d7f57eb8 486 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 258 285 2.3E-80 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CFK41_RS12915 004c1487717966ec089f3f26d7f57eb8 486 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 12 35 2.3E-80 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CFK41_RS12915 004c1487717966ec089f3f26d7f57eb8 486 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 366 388 2.3E-80 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CFK41_RS12915 004c1487717966ec089f3f26d7f57eb8 486 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 128 153 2.3E-80 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CFK41_RS12915 004c1487717966ec089f3f26d7f57eb8 486 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 176 204 2.3E-80 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CFK41_RS12915 004c1487717966ec089f3f26d7f57eb8 486 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 75 104 2.3E-80 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CFK41_RS12915 004c1487717966ec089f3f26d7f57eb8 486 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 13 478 3.1E-199 T 28-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CFK41_RS12915 004c1487717966ec089f3f26d7f57eb8 486 Gene3D G3DSA:1.20.5.320 445 486 3.8E-19 T 28-03-2018 CFK41_RS12915 004c1487717966ec089f3f26d7f57eb8 486 Gene3D G3DSA:3.40.50.720 9 188 8.8E-36 T 28-03-2018 CFK41_RS12915 004c1487717966ec089f3f26d7f57eb8 486 PIRSF PIRSF000109 7 485 1.6E-195 T 28-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CFK41_RS12915 004c1487717966ec089f3f26d7f57eb8 486 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 13 182 1.7E-48 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CFK41_RS12915 004c1487717966ec089f3f26d7f57eb8 486 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 262 274 - T 28-03-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CFK41_RS12915 004c1487717966ec089f3f26d7f57eb8 486 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 187 476 4.1E-124 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CFK41_RS12915 004c1487717966ec089f3f26d7f57eb8 486 SUPERFAMILY SSF48179 185 480 8.5E-119 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CFK41_RS12915 004c1487717966ec089f3f26d7f57eb8 486 SMART SM01350 187 477 6.3E-200 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CFK41_RS12915 004c1487717966ec089f3f26d7f57eb8 486 SUPERFAMILY SSF51735 12 184 3.03E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS12915 004c1487717966ec089f3f26d7f57eb8 486 Gene3D G3DSA:1.10.1040.10 189 444 1.4E-103 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CFK41_RS05420 e318f507377f5b014f9edad9712cc747 390 Gene3D G3DSA:3.30.360.10 144 372 2.8E-39 T 28-03-2018 CFK41_RS05420 e318f507377f5b014f9edad9712cc747 390 Gene3D G3DSA:3.40.50.720 1 143 1.6E-32 T 28-03-2018 CFK41_RS05420 e318f507377f5b014f9edad9712cc747 390 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 7 119 2.1E-13 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS05420 e318f507377f5b014f9edad9712cc747 390 SUPERFAMILY SSF55347 133 271 1.01E-27 T 28-03-2018 CFK41_RS05420 e318f507377f5b014f9edad9712cc747 390 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 140 242 4.4E-12 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CFK41_RS05420 e318f507377f5b014f9edad9712cc747 390 SUPERFAMILY SSF51735 4 158 2.03E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS07120 3007ef29397ef393cbf6fde7ced17954 378 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 95 225 1.5E-58 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CFK41_RS07120 3007ef29397ef393cbf6fde7ced17954 378 Gene3D G3DSA:3.40.50.300 76 242 2.2E-22 T 28-03-2018 CFK41_RS07120 3007ef29397ef393cbf6fde7ced17954 378 PIRSF PIRSF002849 47 378 1.0E-119 T 28-03-2018 CFK41_RS07120 3007ef29397ef393cbf6fde7ced17954 378 Gene3D G3DSA:1.10.8.300 258 375 2.3E-32 T 28-03-2018 CFK41_RS07120 3007ef29397ef393cbf6fde7ced17954 378 SUPERFAMILY SSF52540 71 350 1.94E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS00650 4c9a228079b132c89a549e57ac7ec554 331 Pfam PF00491 Arginase family 44 322 3.0E-52 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CFK41_RS00650 4c9a228079b132c89a549e57ac7ec554 331 Gene3D G3DSA:3.40.800.10 1 330 2.4E-73 T 28-03-2018 CFK41_RS00650 4c9a228079b132c89a549e57ac7ec554 331 Hamap MF_00737 Formimidoylglutamase [hutG]. 6 324 38.951 T 28-03-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 CFK41_RS00650 4c9a228079b132c89a549e57ac7ec554 331 ProSitePatterns PS01053 Arginase family signature. 253 274 - T 28-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 CFK41_RS00650 4c9a228079b132c89a549e57ac7ec554 331 TIGRFAM TIGR01227 hutG: formimidoylglutamase 13 323 6.0E-88 T 28-03-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 CFK41_RS00650 4c9a228079b132c89a549e57ac7ec554 331 SUPERFAMILY SSF52768 18 324 2.34E-68 T 28-03-2018 CFK41_RS00650 4c9a228079b132c89a549e57ac7ec554 331 PIRSF PIRSF036979 25 329 7.7E-22 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CFK41_RS07905 a124613c25c36f85841c9dc57e459cf2 206 SUPERFAMILY SSF48498 118 203 5.04E-16 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CFK41_RS07905 a124613c25c36f85841c9dc57e459cf2 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 77 7.0E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS07905 a124613c25c36f85841c9dc57e459cf2 206 SUPERFAMILY SSF46689 22 86 6.14E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS07905 a124613c25c36f85841c9dc57e459cf2 206 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 123 193 1.0E-7 T 28-03-2018 CFK41_RS07905 a124613c25c36f85841c9dc57e459cf2 206 Gene3D G3DSA:1.10.357.10 76 205 9.0E-16 T 28-03-2018 CFK41_RS07905 a124613c25c36f85841c9dc57e459cf2 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 44 2.8E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS07905 a124613c25c36f85841c9dc57e459cf2 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 52 75 2.8E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS07905 a124613c25c36f85841c9dc57e459cf2 206 Gene3D G3DSA:1.10.10.60 1 75 2.4E-18 T 28-03-2018 CFK41_RS06710 2998410c06281ef49ecab17fcd511a98 257 SMART SM00382 32 212 1.0E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS06710 2998410c06281ef49ecab17fcd511a98 257 SUPERFAMILY SSF52540 6 250 9.35E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS06710 2998410c06281ef49ecab17fcd511a98 257 Pfam PF00005 ABC transporter 23 173 8.2E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS06710 2998410c06281ef49ecab17fcd511a98 257 Gene3D G3DSA:3.40.50.300 3 257 3.8E-55 T 28-03-2018 CFK41_RS06760 c464e2f5fc4ea3a735d04a35177e3184 408 Pfam PF01571 Aminomethyltransferase folate-binding domain 35 267 2.0E-46 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal CFK41_RS06760 c464e2f5fc4ea3a735d04a35177e3184 408 Gene3D G3DSA:4.10.1250.10 247 291 1.1E-13 T 28-03-2018 CFK41_RS06760 c464e2f5fc4ea3a735d04a35177e3184 408 Gene3D G3DSA:3.30.1360.120 137 242 1.8E-15 T 28-03-2018 CFK41_RS06760 c464e2f5fc4ea3a735d04a35177e3184 408 PIRSF PIRSF006487 8 399 4.6E-74 T 28-03-2018 CFK41_RS06760 c464e2f5fc4ea3a735d04a35177e3184 408 Gene3D G3DSA:3.30.1360.120 15 136 3.0E-17 T 28-03-2018 CFK41_RS06760 c464e2f5fc4ea3a735d04a35177e3184 408 SUPERFAMILY SSF103025 15 294 3.77E-73 T 28-03-2018 CFK41_RS06760 c464e2f5fc4ea3a735d04a35177e3184 408 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 279 384 2.4E-20 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CFK41_RS06760 c464e2f5fc4ea3a735d04a35177e3184 408 SUPERFAMILY SSF101790 296 396 7.03E-17 T 28-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain CFK41_RS06760 c464e2f5fc4ea3a735d04a35177e3184 408 Gene3D G3DSA:2.40.30.110 294 402 2.3E-23 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CFK41_RS11080 f606e4ad1bc66ce0ebc283a9acb53f4f 156 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 147 1.9E-50 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CFK41_RS11080 f606e4ad1bc66ce0ebc283a9acb53f4f 156 Gene3D G3DSA:3.40.1400.10 1 155 1.3E-56 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CFK41_RS11080 f606e4ad1bc66ce0ebc283a9acb53f4f 156 SUPERFAMILY SSF89623 1 149 7.46E-51 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CFK41_RS11080 f606e4ad1bc66ce0ebc283a9acb53f4f 156 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 1 148 1.2E-60 T 28-03-2018 IPR011860 Ribose 5-phosphate isomerase GO:0004751 CFK41_RS11080 f606e4ad1bc66ce0ebc283a9acb53f4f 156 PIRSF PIRSF005384 1 149 1.9E-49 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CFK41_RS11080 f606e4ad1bc66ce0ebc283a9acb53f4f 156 Pfam PF02502 Ribose/Galactose Isomerase 3 140 7.6E-47 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CFK41_RS17470 8c01a4ea5a79e043c453d8c082492dc9 374 SUPERFAMILY SSF55979 248 374 9.71E-28 T 28-03-2018 CFK41_RS17470 8c01a4ea5a79e043c453d8c082492dc9 374 Pfam PF02767 DNA polymerase III beta subunit, central domain 128 245 2.2E-28 T 28-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CFK41_RS17470 8c01a4ea5a79e043c453d8c082492dc9 374 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 2 119 2.5E-31 T 28-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CFK41_RS17470 8c01a4ea5a79e043c453d8c082492dc9 374 SUPERFAMILY SSF55979 2 119 3.14E-21 T 28-03-2018 CFK41_RS17470 8c01a4ea5a79e043c453d8c082492dc9 374 Gene3D G3DSA:3.10.150.10 1 122 4.5E-29 T 28-03-2018 CFK41_RS17470 8c01a4ea5a79e043c453d8c082492dc9 374 SUPERFAMILY SSF55979 128 249 1.14E-20 T 28-03-2018 CFK41_RS17470 8c01a4ea5a79e043c453d8c082492dc9 374 PIRSF PIRSF000804 1 374 6.2E-94 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CFK41_RS17470 8c01a4ea5a79e043c453d8c082492dc9 374 Gene3D G3DSA:3.10.150.10 124 250 5.9E-32 T 28-03-2018 CFK41_RS17470 8c01a4ea5a79e043c453d8c082492dc9 374 SMART SM00480 17 370 2.9E-106 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CFK41_RS17470 8c01a4ea5a79e043c453d8c082492dc9 374 Gene3D G3DSA:3.10.150.10 251 374 6.1E-28 T 28-03-2018 CFK41_RS17470 8c01a4ea5a79e043c453d8c082492dc9 374 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 373 2.6E-84 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CFK41_RS17470 8c01a4ea5a79e043c453d8c082492dc9 374 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 248 373 1.1E-28 T 28-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CFK41_RS16815 860b744a092ba52c70e151697fd61f16 212 Gene3D G3DSA:1.10.10.60 32 71 9.2E-19 T 28-03-2018 CFK41_RS16815 860b744a092ba52c70e151697fd61f16 212 SUPERFAMILY SSF48498 95 202 2.22E-9 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CFK41_RS16815 860b744a092ba52c70e151697fd61f16 212 Gene3D G3DSA:1.10.260.40 8 31 0.46 T 28-03-2018 CFK41_RS16815 860b744a092ba52c70e151697fd61f16 212 SUPERFAMILY SSF46689 16 97 1.55E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS16815 860b744a092ba52c70e151697fd61f16 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 75 4.2E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS16815 860b744a092ba52c70e151697fd61f16 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 1.9E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS16815 860b744a092ba52c70e151697fd61f16 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 1.9E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS16815 860b744a092ba52c70e151697fd61f16 212 Gene3D G3DSA:1.10.357.10 72 201 1.2E-22 T 28-03-2018 CFK41_RS08525 3a3305fdd667a2a94a252dc033f69b4f 607 SUPERFAMILY SSF51230 154 245 1.7E-26 T 28-03-2018 IPR011053 Single hybrid motif CFK41_RS08525 3a3305fdd667a2a94a252dc033f69b4f 607 SUPERFAMILY SSF51230 3 92 2.88E-25 T 28-03-2018 IPR011053 Single hybrid motif CFK41_RS08525 3a3305fdd667a2a94a252dc033f69b4f 607 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CFK41_RS08525 3a3305fdd667a2a94a252dc033f69b4f 607 SUPERFAMILY SSF52777 372 598 2.0E-74 T 28-03-2018 CFK41_RS08525 3a3305fdd667a2a94a252dc033f69b4f 607 TIGRFAM TIGR02927 SucB_Actino: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase 1 607 3.6E-232 T 28-03-2018 IPR014276 2-oxoglutarate dehydrogenase, E2 component KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 CFK41_RS08525 3a3305fdd667a2a94a252dc033f69b4f 607 Pfam PF00364 Biotin-requiring enzyme 4 76 1.1E-21 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CFK41_RS08525 3a3305fdd667a2a94a252dc033f69b4f 607 Pfam PF00364 Biotin-requiring enzyme 154 225 6.1E-21 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CFK41_RS08525 3a3305fdd667a2a94a252dc033f69b4f 607 Gene3D G3DSA:3.90.1170.30 46 195 9.8E-34 T 28-03-2018 CFK41_RS08525 3a3305fdd667a2a94a252dc033f69b4f 607 Gene3D G3DSA:3.90.1170.30 1 45 3.8E-20 T 28-03-2018 CFK41_RS08525 3a3305fdd667a2a94a252dc033f69b4f 607 Gene3D G3DSA:3.90.1170.30 196 311 2.1E-10 T 28-03-2018 CFK41_RS08525 3a3305fdd667a2a94a252dc033f69b4f 607 Pfam PF02817 e3 binding domain 304 337 2.1E-13 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CFK41_RS08525 3a3305fdd667a2a94a252dc033f69b4f 607 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 177 206 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CFK41_RS08525 3a3305fdd667a2a94a252dc033f69b4f 607 Gene3D G3DSA:4.10.320.10 312 349 2.7E-18 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CFK41_RS08525 3a3305fdd667a2a94a252dc033f69b4f 607 SUPERFAMILY SSF47005 300 341 3.01E-11 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CFK41_RS08525 3a3305fdd667a2a94a252dc033f69b4f 607 Gene3D G3DSA:3.30.559.10 353 600 6.3E-74 T 28-03-2018 CFK41_RS08525 3a3305fdd667a2a94a252dc033f69b4f 607 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 372 598 7.2E-71 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CFK41_RS11655 f423ab06ad434d150978b2a712934bde 198 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 60 82 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CFK41_RS11655 f423ab06ad434d150978b2a712934bde 198 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 13 179 1.4E-38 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CFK41_RS11655 f423ab06ad434d150978b2a712934bde 198 Pfam PF01066 CDP-alcohol phosphatidyltransferase 13 82 7.4E-14 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CFK41_RS11655 f423ab06ad434d150978b2a712934bde 198 PIRSF PIRSF000847 10 194 1.2E-42 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CFK41_RS10995 4ef2210746a5c59590d7116f65306538 213 Gene3D G3DSA:3.40.50.2300 1 142 6.0E-30 T 28-03-2018 CFK41_RS10995 4ef2210746a5c59590d7116f65306538 213 SMART SM00421 147 204 5.9E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS10995 4ef2210746a5c59590d7116f65306538 213 Gene3D G3DSA:1.10.10.10 143 211 2.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS10995 4ef2210746a5c59590d7116f65306538 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 6.4E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS10995 4ef2210746a5c59590d7116f65306538 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 6.4E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS10995 4ef2210746a5c59590d7116f65306538 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 6.4E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS10995 4ef2210746a5c59590d7116f65306538 213 SUPERFAMILY SSF52172 2 131 1.99E-25 T 28-03-2018 IPR011006 CheY-like superfamily CFK41_RS10995 4ef2210746a5c59590d7116f65306538 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 199 8.3E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS10995 4ef2210746a5c59590d7116f65306538 213 Pfam PF00072 Response regulator receiver domain 3 108 2.0E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS10995 4ef2210746a5c59590d7116f65306538 213 SUPERFAMILY SSF46894 138 203 2.24E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CFK41_RS10995 4ef2210746a5c59590d7116f65306538 213 SMART SM00448 1 120 1.8E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS03835 0eabba0a726b476c08973c5185f06308 557 Pfam PF01268 Formate--tetrahydrofolate ligase 7 557 4.3E-248 T 28-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CFK41_RS03835 0eabba0a726b476c08973c5185f06308 557 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 329 340 - T 28-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CFK41_RS03835 0eabba0a726b476c08973c5185f06308 557 Gene3D G3DSA:3.40.50.300 234 443 3.3E-66 T 28-03-2018 CFK41_RS03835 0eabba0a726b476c08973c5185f06308 557 Gene3D G3DSA:3.40.50.300 15 233 1.9E-84 T 28-03-2018 CFK41_RS03835 0eabba0a726b476c08973c5185f06308 557 Gene3D G3DSA:3.10.410.10 445 533 1.1E-33 T 28-03-2018 CFK41_RS03835 0eabba0a726b476c08973c5185f06308 557 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 104 114 - T 28-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CFK41_RS03835 0eabba0a726b476c08973c5185f06308 557 SUPERFAMILY SSF52540 7 555 5.67E-226 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS03835 0eabba0a726b476c08973c5185f06308 557 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 4 557 46.468 T 28-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CFK41_RS17620 61db8505e8cb5c919883fc60d26e9c1f 274 Gene3D G3DSA:3.40.50.1820 4 274 3.1E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS17620 61db8505e8cb5c919883fc60d26e9c1f 274 Pfam PF12146 Serine aminopeptidase, S33 28 254 6.9E-58 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CFK41_RS17620 61db8505e8cb5c919883fc60d26e9c1f 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 57 72 1.2E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CFK41_RS17620 61db8505e8cb5c919883fc60d26e9c1f 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 1.2E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CFK41_RS17620 61db8505e8cb5c919883fc60d26e9c1f 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 209 223 1.2E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CFK41_RS17620 61db8505e8cb5c919883fc60d26e9c1f 274 SUPERFAMILY SSF53474 199 271 5.9E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS17620 61db8505e8cb5c919883fc60d26e9c1f 274 SUPERFAMILY SSF53474 8 141 5.9E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS00400 eee7784cca134b49fc50eb47058a6f80 318 Pfam PF00733 Asparagine synthase 46 120 1.6E-6 T 28-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CFK41_RS00400 eee7784cca134b49fc50eb47058a6f80 318 SUPERFAMILY SSF52402 60 250 1.68E-26 T 28-03-2018 CFK41_RS00400 eee7784cca134b49fc50eb47058a6f80 318 Gene3D G3DSA:3.40.50.620 58 265 1.3E-23 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS00400 eee7784cca134b49fc50eb47058a6f80 318 TIGRFAM TIGR00268 TIGR00268: TIGR00268 family protein 55 305 4.6E-52 T 28-03-2018 IPR005232 Lactate racemization operon protein LarE CFK41_RS00400 eee7784cca134b49fc50eb47058a6f80 318 PIRSF PIRSF006661 41 312 7.5E-84 T 28-03-2018 IPR005232 Lactate racemization operon protein LarE CFK41_RS11105 3ba5ccd506fa00e4dd307b307502183a 382 SUPERFAMILY SSF56112 6 271 4.45E-54 T 28-03-2018 IPR011009 Protein kinase-like domain CFK41_RS11105 3ba5ccd506fa00e4dd307b307502183a 382 SMART SM00220 9 269 1.2E-39 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CFK41_RS11105 3ba5ccd506fa00e4dd307b307502183a 382 Gene3D G3DSA:3.30.200.20 2 89 5.1E-12 T 28-03-2018 CFK41_RS11105 3ba5ccd506fa00e4dd307b307502183a 382 Gene3D G3DSA:1.10.510.10 90 280 3.4E-40 T 28-03-2018 CFK41_RS11105 3ba5ccd506fa00e4dd307b307502183a 382 Pfam PF00069 Protein kinase domain 12 261 1.2E-35 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CFK41_RS07485 8531d9eeff3aea85d831bb72d58f2f92 209 SMART SM00448 10 123 6.4E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS07485 8531d9eeff3aea85d831bb72d58f2f92 209 SUPERFAMILY SSF52172 9 134 3.56E-25 T 28-03-2018 IPR011006 CheY-like superfamily CFK41_RS07485 8531d9eeff3aea85d831bb72d58f2f92 209 SMART SM00421 141 198 9.4E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS07485 8531d9eeff3aea85d831bb72d58f2f92 209 Gene3D G3DSA:1.10.10.10 143 204 3.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS07485 8531d9eeff3aea85d831bb72d58f2f92 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 174 2.7E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS07485 8531d9eeff3aea85d831bb72d58f2f92 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 144 158 2.7E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS07485 8531d9eeff3aea85d831bb72d58f2f92 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 186 2.7E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS07485 8531d9eeff3aea85d831bb72d58f2f92 209 Pfam PF00072 Response regulator receiver domain 12 123 5.6E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS07485 8531d9eeff3aea85d831bb72d58f2f92 209 SUPERFAMILY SSF46894 137 199 3.06E-13 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CFK41_RS07485 8531d9eeff3aea85d831bb72d58f2f92 209 Gene3D G3DSA:3.40.50.2300 9 142 3.1E-25 T 28-03-2018 CFK41_RS07485 8531d9eeff3aea85d831bb72d58f2f92 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 144 198 1.3E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS09070 b08faf2e2568f3b3961d870eb55075a7 175 Pfam PF12840 Helix-turn-helix domain 7 65 4.2E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS09070 b08faf2e2568f3b3961d870eb55075a7 175 Gene3D G3DSA:1.10.10.10 2 83 7.6E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS09070 b08faf2e2568f3b3961d870eb55075a7 175 SUPERFAMILY SSF46785 7 106 2.9E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS04455 6b42c0638b9cbdc039b4b81f65af6b32 362 SUPERFAMILY SSF51004 39 358 2.88E-15 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain CFK41_RS04455 6b42c0638b9cbdc039b4b81f65af6b32 362 Gene3D G3DSA:2.130.10.10 142 361 1.9E-11 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CFK41_RS04455 6b42c0638b9cbdc039b4b81f65af6b32 362 Gene3D G3DSA:2.130.10.10 3 141 0.013 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CFK41_RS04455 6b42c0638b9cbdc039b4b81f65af6b32 362 Pfam PF10282 Lactonase, 7-bladed beta-propeller 9 358 2.9E-49 T 28-03-2018 IPR019405 Lactonase, 7-bladed beta propeller CFK41_RS10460 5bd999d9613bd59cbcd7fb67ed4e3411 502 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 19 501 35.786 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CFK41_RS10460 5bd999d9613bd59cbcd7fb67ed4e3411 502 Pfam PF00152 tRNA synthetases class II (D, K and N) 159 498 1.1E-68 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS10460 5bd999d9613bd59cbcd7fb67ed4e3411 502 Gene3D G3DSA:2.40.50.140 13 153 6.3E-36 T 28-03-2018 CFK41_RS10460 5bd999d9613bd59cbcd7fb67ed4e3411 502 Pfam PF01336 OB-fold nucleic acid binding domain 67 142 5.9E-10 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CFK41_RS10460 5bd999d9613bd59cbcd7fb67ed4e3411 502 Gene3D G3DSA:3.30.930.10 154 498 3.0E-84 T 28-03-2018 CFK41_RS10460 5bd999d9613bd59cbcd7fb67ed4e3411 502 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 13 501 8.3E-144 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CFK41_RS10460 5bd999d9613bd59cbcd7fb67ed4e3411 502 PRINTS PR00982 Lysyl-tRNA synthetase signature 196 206 6.6E-31 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CFK41_RS10460 5bd999d9613bd59cbcd7fb67ed4e3411 502 PRINTS PR00982 Lysyl-tRNA synthetase signature 241 254 6.6E-31 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CFK41_RS10460 5bd999d9613bd59cbcd7fb67ed4e3411 502 PRINTS PR00982 Lysyl-tRNA synthetase signature 259 276 6.6E-31 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CFK41_RS10460 5bd999d9613bd59cbcd7fb67ed4e3411 502 PRINTS PR00982 Lysyl-tRNA synthetase signature 212 228 6.6E-31 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CFK41_RS10460 5bd999d9613bd59cbcd7fb67ed4e3411 502 PRINTS PR00982 Lysyl-tRNA synthetase signature 384 400 6.6E-31 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CFK41_RS10460 5bd999d9613bd59cbcd7fb67ed4e3411 502 SUPERFAMILY SSF55681 159 499 6.22E-99 T 28-03-2018 CFK41_RS10460 5bd999d9613bd59cbcd7fb67ed4e3411 502 SUPERFAMILY SSF50249 12 152 4.16E-31 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS12075 54357ac45b505dceb16a402875373831 893 SUPERFAMILY SSF52374 392 644 1.02E-100 T 28-03-2018 CFK41_RS12075 54357ac45b505dceb16a402875373831 893 SUPERFAMILY SSF52374 11 227 1.02E-100 T 28-03-2018 CFK41_RS12075 54357ac45b505dceb16a402875373831 893 Gene3D G3DSA:3.40.50.620 10 638 3.6E-98 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS12075 54357ac45b505dceb16a402875373831 893 Gene3D G3DSA:1.10.730.10 639 827 1.5E-31 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS12075 54357ac45b505dceb16a402875373831 893 SUPERFAMILY SSF50677 233 383 5.49E-31 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CFK41_RS12075 54357ac45b505dceb16a402875373831 893 SUPERFAMILY SSF47323 653 872 4.11E-32 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS12075 54357ac45b505dceb16a402875373831 893 Pfam PF08264 Anticodon-binding domain of tRNA 687 832 1.3E-25 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CFK41_RS12075 54357ac45b505dceb16a402875373831 893 Hamap MF_02005 Valine--tRNA ligase [valS]. 12 866 26.998 T 28-03-2018 IPR022874 Valine-tRNA ligase, type 2 GO:0004832 KEGG: 00970+6.1.1.9 CFK41_RS12075 54357ac45b505dceb16a402875373831 893 PRINTS PR00986 Valyl-tRNA synthetase signature 47 58 9.0E-19 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CFK41_RS12075 54357ac45b505dceb16a402875373831 893 PRINTS PR00986 Valyl-tRNA synthetase signature 397 410 9.0E-19 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CFK41_RS12075 54357ac45b505dceb16a402875373831 893 PRINTS PR00986 Valyl-tRNA synthetase signature 520 541 9.0E-19 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CFK41_RS12075 54357ac45b505dceb16a402875373831 893 PRINTS PR00986 Valyl-tRNA synthetase signature 269 286 9.0E-19 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CFK41_RS12075 54357ac45b505dceb16a402875373831 893 PRINTS PR00986 Valyl-tRNA synthetase signature 553 571 9.0E-19 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CFK41_RS12075 54357ac45b505dceb16a402875373831 893 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 28 106 2.6E-16 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS12075 54357ac45b505dceb16a402875373831 893 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 135 639 7.5E-74 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS12075 54357ac45b505dceb16a402875373831 893 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 54 65 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS08395 d75747192b6a5c0939dacbc485a0f84f 914 SUPERFAMILY SSF52922 723 900 2.27E-49 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CFK41_RS08395 d75747192b6a5c0939dacbc485a0f84f 914 SUPERFAMILY SSF52518 69 487 2.26E-121 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CFK41_RS08395 d75747192b6a5c0939dacbc485a0f84f 914 SUPERFAMILY SSF52518 491 721 1.41E-82 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CFK41_RS08395 d75747192b6a5c0939dacbc485a0f84f 914 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 18 903 0.0 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CFK41_RS08395 d75747192b6a5c0939dacbc485a0f84f 914 Gene3D G3DSA:3.40.50.970 68 489 3.6E-77 T 28-03-2018 CFK41_RS08395 d75747192b6a5c0939dacbc485a0f84f 914 Gene3D G3DSA:3.40.50.970 490 726 5.0E-65 T 28-03-2018 CFK41_RS08395 d75747192b6a5c0939dacbc485a0f84f 914 PIRSF PIRSF000156 10 908 0.0 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CFK41_RS08395 d75747192b6a5c0939dacbc485a0f84f 914 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 147 306 8.8E-11 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CFK41_RS08395 d75747192b6a5c0939dacbc485a0f84f 914 Gene3D G3DSA:3.40.50.920 728 907 2.5E-36 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CFK41_RS09410 e4e972e0052f0b6e79cba9e04d57932f 188 SUPERFAMILY SSF52499 6 168 1.28E-34 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CFK41_RS09410 e4e972e0052f0b6e79cba9e04d57932f 188 Gene3D G3DSA:3.40.50.850 4 188 2.3E-32 T 28-03-2018 CFK41_RS09410 e4e972e0052f0b6e79cba9e04d57932f 188 Pfam PF00857 Isochorismatase family 8 168 2.0E-25 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CFK41_RS05885 0dc9970d2c0d5adf6c761236fe6d282e 558 Gene3D G3DSA:1.10.510.10 84 310 1.1E-35 T 28-03-2018 CFK41_RS05885 0dc9970d2c0d5adf6c761236fe6d282e 558 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CFK41_RS05885 0dc9970d2c0d5adf6c761236fe6d282e 558 SMART SM00220 15 276 8.7E-35 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CFK41_RS05885 0dc9970d2c0d5adf6c761236fe6d282e 558 SUPERFAMILY SSF56112 14 275 1.89E-54 T 28-03-2018 IPR011009 Protein kinase-like domain CFK41_RS05885 0dc9970d2c0d5adf6c761236fe6d282e 558 Pfam PF00069 Protein kinase domain 15 230 1.7E-37 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CFK41_RS05885 0dc9970d2c0d5adf6c761236fe6d282e 558 Gene3D G3DSA:3.30.200.20 6 83 1.7E-16 T 28-03-2018 CFK41_RS05885 0dc9970d2c0d5adf6c761236fe6d282e 558 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 44 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CFK41_RS06985 cd774483ab9b730d1aba4837ad4f91bc 417 SUPERFAMILY SSF53850 13 412 7.25E-48 T 28-03-2018 CFK41_RS06985 cd774483ab9b730d1aba4837ad4f91bc 417 Gene3D G3DSA:3.40.190.10 14 189 1.7E-23 T 28-03-2018 CFK41_RS06985 cd774483ab9b730d1aba4837ad4f91bc 417 Gene3D G3DSA:3.40.190.10 206 368 1.4E-9 T 28-03-2018 CFK41_RS06985 cd774483ab9b730d1aba4837ad4f91bc 417 Pfam PF13416 Bacterial extracellular solute-binding protein 67 338 6.5E-25 T 28-03-2018 CFK41_RS07005 a4f3035a4f73fd55ea9e61e80fb409ca 70 ProSitePatterns PS01143 Ribosomal protein L31 signature. 36 57 - T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS07005 a4f3035a4f73fd55ea9e61e80fb409ca 70 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 69 29.747 T 28-03-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS07005 a4f3035a4f73fd55ea9e61e80fb409ca 70 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 67 1.3E-33 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS07005 a4f3035a4f73fd55ea9e61e80fb409ca 70 Pfam PF01197 Ribosomal protein L31 1 66 3.1E-32 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS07005 a4f3035a4f73fd55ea9e61e80fb409ca 70 PRINTS PR01249 Ribosomal protein L31 signature 32 47 5.0E-21 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS07005 a4f3035a4f73fd55ea9e61e80fb409ca 70 PRINTS PR01249 Ribosomal protein L31 signature 47 65 5.0E-21 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS07005 a4f3035a4f73fd55ea9e61e80fb409ca 70 PRINTS PR01249 Ribosomal protein L31 signature 2 19 5.0E-21 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS07005 a4f3035a4f73fd55ea9e61e80fb409ca 70 SUPERFAMILY SSF143800 1 66 2.51E-25 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS07995 bf6fb5ef7c3b1d9c2142cd1d9ea64b27 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 116 129 5.2E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CFK41_RS07995 bf6fb5ef7c3b1d9c2142cd1d9ea64b27 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 17 28 5.2E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CFK41_RS07995 bf6fb5ef7c3b1d9c2142cd1d9ea64b27 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 150 166 5.2E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CFK41_RS07995 bf6fb5ef7c3b1d9c2142cd1d9ea64b27 216 Gene3D G3DSA:3.40.50.1000 6 215 8.9E-16 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS07995 bf6fb5ef7c3b1d9c2142cd1d9ea64b27 216 SUPERFAMILY SSF56784 18 214 5.27E-21 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS07995 bf6fb5ef7c3b1d9c2142cd1d9ea64b27 216 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 93 211 4.3E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CFK41_RS12285 32de408166735c3bfc766ad949c0764e 160 SMART SM01058 2 112 1.3E-30 T 28-03-2018 IPR003711 CarD-like/TRCF domain CFK41_RS12285 32de408166735c3bfc766ad949c0764e 160 Pfam PF02559 CarD-like/TRCF domain 3 111 1.4E-17 T 28-03-2018 IPR003711 CarD-like/TRCF domain CFK41_RS12285 32de408166735c3bfc766ad949c0764e 160 SUPERFAMILY SSF141259 2 66 7.72E-14 T 28-03-2018 IPR003711 CarD-like/TRCF domain CFK41_RS08190 80ddfe5b39a8fbef40844cbbf2cc11f2 444 Pfam PF00571 CBS domain 210 268 1.3E-10 T 28-03-2018 IPR000644 CBS domain CFK41_RS08190 80ddfe5b39a8fbef40844cbbf2cc11f2 444 Pfam PF00571 CBS domain 279 333 8.1E-5 T 28-03-2018 IPR000644 CBS domain CFK41_RS08190 80ddfe5b39a8fbef40844cbbf2cc11f2 444 Pfam PF01595 Domain of unknown function DUF21 10 166 7.7E-10 T 28-03-2018 IPR002550 Domain of unknown function DUF21 CFK41_RS08190 80ddfe5b39a8fbef40844cbbf2cc11f2 444 SMART SM00116 219 268 5.6E-5 T 28-03-2018 IPR000644 CBS domain CFK41_RS08190 80ddfe5b39a8fbef40844cbbf2cc11f2 444 SUPERFAMILY SSF54631 206 350 1.26E-35 T 28-03-2018 CFK41_RS08190 80ddfe5b39a8fbef40844cbbf2cc11f2 444 Gene3D G3DSA:3.30.465.10 342 430 3.5E-21 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CFK41_RS08190 80ddfe5b39a8fbef40844cbbf2cc11f2 444 Pfam PF03471 Transporter associated domain 350 425 8.3E-11 T 28-03-2018 IPR005170 Transporter-associated domain CFK41_RS08190 80ddfe5b39a8fbef40844cbbf2cc11f2 444 SUPERFAMILY SSF56176 346 435 1.01E-13 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CFK41_RS08190 80ddfe5b39a8fbef40844cbbf2cc11f2 444 SMART SM01091 348 428 7.7E-17 T 28-03-2018 IPR005170 Transporter-associated domain CFK41_RS08190 80ddfe5b39a8fbef40844cbbf2cc11f2 444 Gene3D G3DSA:3.10.580.10 190 341 4.0E-34 T 28-03-2018 CFK41_RS12010 84bb7659d8ffb3300acb7d7e92f287a6 90 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 42 50 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CFK41_RS12010 84bb7659d8ffb3300acb7d7e92f287a6 90 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 15 80 1.8E-15 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CFK41_RS12010 84bb7659d8ffb3300acb7d7e92f287a6 90 SUPERFAMILY SSF54292 7 90 2.23E-24 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CFK41_RS12010 84bb7659d8ffb3300acb7d7e92f287a6 90 Gene3D G3DSA:3.10.20.30 4 90 6.0E-21 T 28-03-2018 IPR012675 Beta-grasp domain CFK41_RS16540 e36690ad3b566a902cffac2024a8c18b 334 SUPERFAMILY SSF50129 1 175 4.72E-32 T 28-03-2018 IPR011032 GroES-like CFK41_RS16540 e36690ad3b566a902cffac2024a8c18b 334 SMART SM00829 7 332 0.0056 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CFK41_RS16540 e36690ad3b566a902cffac2024a8c18b 334 Pfam PF00107 Zinc-binding dehydrogenase 176 296 1.3E-16 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CFK41_RS16540 e36690ad3b566a902cffac2024a8c18b 334 Gene3D G3DSA:3.40.50.720 173 285 5.0E-20 T 28-03-2018 CFK41_RS16540 e36690ad3b566a902cffac2024a8c18b 334 Gene3D G3DSA:3.90.180.10 1 172 4.7E-32 T 28-03-2018 CFK41_RS16540 e36690ad3b566a902cffac2024a8c18b 334 SUPERFAMILY SSF51735 141 297 3.16E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS16540 e36690ad3b566a902cffac2024a8c18b 334 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 133 2.3E-10 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CFK41_RS04485 d7f32fbde8c691c96bc0d32e8f15eb98 317 SMART SM00738 130 238 5.4E-40 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CFK41_RS04485 d7f32fbde8c691c96bc0d32e8f15eb98 317 PRINTS PR00338 Transcription termination factor NUSG signature 275 290 1.2E-16 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CFK41_RS04485 d7f32fbde8c691c96bc0d32e8f15eb98 317 PRINTS PR00338 Transcription termination factor NUSG signature 185 197 1.2E-16 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CFK41_RS04485 d7f32fbde8c691c96bc0d32e8f15eb98 317 PRINTS PR00338 Transcription termination factor NUSG signature 293 309 1.2E-16 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CFK41_RS04485 d7f32fbde8c691c96bc0d32e8f15eb98 317 ProSitePatterns PS01014 Transcription termination factor nusG signature. 300 309 - T 28-03-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site CFK41_RS04485 d7f32fbde8c691c96bc0d32e8f15eb98 317 Gene3D G3DSA:2.30.30.30 258 317 2.9E-17 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CFK41_RS04485 d7f32fbde8c691c96bc0d32e8f15eb98 317 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 130 317 21.751 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CFK41_RS04485 d7f32fbde8c691c96bc0d32e8f15eb98 317 SUPERFAMILY SSF50104 263 317 3.01E-15 T 28-03-2018 IPR008991 Translation protein SH3-like domain CFK41_RS04485 d7f32fbde8c691c96bc0d32e8f15eb98 317 Gene3D G3DSA:3.30.70.940 131 239 8.4E-35 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CFK41_RS04485 d7f32fbde8c691c96bc0d32e8f15eb98 317 SUPERFAMILY SSF82679 132 235 2.62E-34 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CFK41_RS04485 d7f32fbde8c691c96bc0d32e8f15eb98 317 Pfam PF02357 Transcription termination factor nusG 132 234 2.3E-22 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CFK41_RS04485 d7f32fbde8c691c96bc0d32e8f15eb98 317 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 133 317 2.8E-56 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CFK41_RS15415 4b1bcdea333036fb0ee8d8d287a613f2 162 Pfam PF10067 Predicted membrane protein (DUF2306) 9 140 7.0E-12 T 28-03-2018 IPR018750 Protein of unknown function DUF2306, membrane CFK41_RS00070 e358a48f310d1f6e3197b0abbb25e80f 403 SUPERFAMILY SSF51556 60 366 1.87E-61 T 28-03-2018 IPR032466 Metal-dependent hydrolase CFK41_RS00070 e358a48f310d1f6e3197b0abbb25e80f 403 Gene3D G3DSA:2.30.40.10 6 67 3.9E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS00070 e358a48f310d1f6e3197b0abbb25e80f 403 SUPERFAMILY SSF51338 16 60 2.88E-10 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS00070 e358a48f310d1f6e3197b0abbb25e80f 403 SUPERFAMILY SSF51338 357 397 2.88E-10 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS00070 e358a48f310d1f6e3197b0abbb25e80f 403 Gene3D G3DSA:3.20.20.140 68 342 1.2E-28 T 28-03-2018 CFK41_RS00070 e358a48f310d1f6e3197b0abbb25e80f 403 Gene3D G3DSA:2.30.40.10 343 402 6.8E-6 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS00070 e358a48f310d1f6e3197b0abbb25e80f 403 Pfam PF07969 Amidohydrolase family 121 396 2.0E-19 T 28-03-2018 IPR013108 Amidohydrolase 3 CFK41_RS10670 8b487df1fdc5f2405e13310eb52da1a0 892 Gene3D G3DSA:1.10.8.60 346 555 1.4E-44 T 28-03-2018 CFK41_RS10670 8b487df1fdc5f2405e13310eb52da1a0 892 SMART SM00382 605 754 1.2E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS10670 8b487df1fdc5f2405e13310eb52da1a0 892 SMART SM00382 200 346 1.8E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS10670 8b487df1fdc5f2405e13310eb52da1a0 892 SUPERFAMILY SSF81923 4 146 4.45E-26 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CFK41_RS10670 8b487df1fdc5f2405e13310eb52da1a0 892 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 639 657 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 CFK41_RS10670 8b487df1fdc5f2405e13310eb52da1a0 892 Pfam PF07724 AAA domain (Cdc48 subfamily) 604 766 1.1E-53 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CFK41_RS10670 8b487df1fdc5f2405e13310eb52da1a0 892 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 205 338 1.1E-13 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CFK41_RS10670 8b487df1fdc5f2405e13310eb52da1a0 892 Gene3D G3DSA:3.40.50.300 159 345 5.5E-24 T 28-03-2018 CFK41_RS10670 8b487df1fdc5f2405e13310eb52da1a0 892 SMART SM01086 772 863 5.6E-34 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CFK41_RS10670 8b487df1fdc5f2405e13310eb52da1a0 892 Gene3D G3DSA:3.40.50.300 560 771 6.4E-48 T 28-03-2018 CFK41_RS10670 8b487df1fdc5f2405e13310eb52da1a0 892 SUPERFAMILY SSF52540 554 852 4.19E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS10670 8b487df1fdc5f2405e13310eb52da1a0 892 Gene3D G3DSA:1.10.8.60 772 874 1.9E-23 T 28-03-2018 CFK41_RS10670 8b487df1fdc5f2405e13310eb52da1a0 892 Gene3D G3DSA:1.10.1780.10 2 147 4.7E-29 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CFK41_RS10670 8b487df1fdc5f2405e13310eb52da1a0 892 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 772 852 6.3E-26 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CFK41_RS10670 8b487df1fdc5f2405e13310eb52da1a0 892 SUPERFAMILY SSF52540 160 553 1.67E-91 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS10670 8b487df1fdc5f2405e13310eb52da1a0 892 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 66 1.6E-9 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CFK41_RS10670 8b487df1fdc5f2405e13310eb52da1a0 892 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 92 141 1.1E-6 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CFK41_RS10670 8b487df1fdc5f2405e13310eb52da1a0 892 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 297 309 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CFK41_RS10670 8b487df1fdc5f2405e13310eb52da1a0 892 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 683 701 4.8E-40 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CFK41_RS10670 8b487df1fdc5f2405e13310eb52da1a0 892 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 716 730 4.8E-40 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CFK41_RS10670 8b487df1fdc5f2405e13310eb52da1a0 892 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 654 672 4.8E-40 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CFK41_RS10670 8b487df1fdc5f2405e13310eb52da1a0 892 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 609 627 4.8E-40 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CFK41_RS11680 dc21b1037af839bf33cbd789e7b2e9db 250 SUPERFAMILY SSF56784 31 234 4.77E-40 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS11680 dc21b1037af839bf33cbd789e7b2e9db 250 Gene3D G3DSA:3.40.50.1000 99 240 3.6E-20 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS11680 dc21b1037af839bf33cbd789e7b2e9db 250 Pfam PF13419 Haloacid dehalogenase-like hydrolase 33 211 4.1E-19 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS11680 dc21b1037af839bf33cbd789e7b2e9db 250 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 117 211 1.1E-12 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CFK41_RS11680 dc21b1037af839bf33cbd789e7b2e9db 250 Gene3D G3DSA:1.10.150.240 45 98 8.3E-7 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CFK41_RS10630 ceac138c554b81c398d720387ca89a13 141 PIRSF PIRSF006246 1 131 3.4E-53 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CFK41_RS10630 ceac138c554b81c398d720387ca89a13 141 Pfam PF02261 Aspartate decarboxylase 1 114 2.3E-51 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CFK41_RS10630 ceac138c554b81c398d720387ca89a13 141 Gene3D G3DSA:2.40.40.20 1 117 5.9E-53 T 28-03-2018 CFK41_RS10630 ceac138c554b81c398d720387ca89a13 141 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 114 3.0E-34 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CFK41_RS10630 ceac138c554b81c398d720387ca89a13 141 SUPERFAMILY SSF50692 1 115 5.78E-48 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CFK41_RS10630 ceac138c554b81c398d720387ca89a13 141 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 130 71.029 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CFK41_RS10630 ceac138c554b81c398d720387ca89a13 141 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 118 7.1E-49 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CFK41_RS12470 7c6714d6ab2be9d2e603a1a4b4334b11 141 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 141 30.996 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CFK41_RS12470 7c6714d6ab2be9d2e603a1a4b4334b11 141 SUPERFAMILY SSF69500 1 140 1.2E-47 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CFK41_RS12470 7c6714d6ab2be9d2e603a1a4b4334b11 141 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 140 2.4E-51 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CFK41_RS12470 7c6714d6ab2be9d2e603a1a4b4334b11 141 Gene3D G3DSA:3.50.80.10 1 141 1.6E-53 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CFK41_RS12470 7c6714d6ab2be9d2e603a1a4b4334b11 141 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 140 2.0E-42 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CFK41_RS10580 ebf519969169ad5ad80304472d4327f0 217 SUPERFAMILY SSF46894 132 195 7.82E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CFK41_RS10580 ebf519969169ad5ad80304472d4327f0 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 165 192 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS10580 ebf519969169ad5ad80304472d4327f0 217 SMART SM00421 148 211 2.5E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS10580 ebf519969169ad5ad80304472d4327f0 217 Pfam PF00072 Response regulator receiver domain 3 95 3.7E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS10580 ebf519969169ad5ad80304472d4327f0 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 194 9.4E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS10580 ebf519969169ad5ad80304472d4327f0 217 SMART SM00448 1 120 2.4E-6 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS10580 ebf519969169ad5ad80304472d4327f0 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 2.8E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS10580 ebf519969169ad5ad80304472d4327f0 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 2.8E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS10580 ebf519969169ad5ad80304472d4327f0 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 2.8E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS10580 ebf519969169ad5ad80304472d4327f0 217 Gene3D G3DSA:3.40.50.2300 1 143 9.8E-24 T 28-03-2018 CFK41_RS10580 ebf519969169ad5ad80304472d4327f0 217 Gene3D G3DSA:1.10.10.10 144 215 3.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS10580 ebf519969169ad5ad80304472d4327f0 217 SUPERFAMILY SSF52172 1 131 5.69E-16 T 28-03-2018 IPR011006 CheY-like superfamily CFK41_RS00410 11ddb2d70307710d86ab1e037e267d80 120 Gene3D G3DSA:1.10.3290.10 5 115 3.3E-4 T 28-03-2018 IPR003812 Fido domain CFK41_RS00410 11ddb2d70307710d86ab1e037e267d80 120 Pfam PF02661 Fic/DOC family 16 77 7.1E-6 T 28-03-2018 IPR003812 Fido domain CFK41_RS00410 11ddb2d70307710d86ab1e037e267d80 120 TIGRFAM TIGR01550 DOC_P1: death-on-curing family protein 47 114 1.9E-12 T 28-03-2018 IPR006440 Death on curing protein GO:0016301 CFK41_RS11075 f00a77405afb8af82a014f8dca5f0d4b 352 Pfam PF06827 Zinc finger found in FPG and IleRS 296 323 1.7E-6 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CFK41_RS11075 f00a77405afb8af82a014f8dca5f0d4b 352 SUPERFAMILY SSF46946 159 246 5.89E-21 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CFK41_RS11075 f00a77405afb8af82a014f8dca5f0d4b 352 SUPERFAMILY SSF57716 284 321 1.48E-10 T 28-03-2018 CFK41_RS11075 f00a77405afb8af82a014f8dca5f0d4b 352 ProSitePatterns PS01242 Zinc finger FPG-type signature. 297 321 - T 28-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 CFK41_RS11075 f00a77405afb8af82a014f8dca5f0d4b 352 SUPERFAMILY SSF81624 116 161 2.88E-14 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CFK41_RS11075 f00a77405afb8af82a014f8dca5f0d4b 352 SUPERFAMILY SSF81624 2 87 2.88E-14 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CFK41_RS11075 f00a77405afb8af82a014f8dca5f0d4b 352 Gene3D G3DSA:3.20.190.10 1 154 7.0E-23 T 28-03-2018 CFK41_RS11075 f00a77405afb8af82a014f8dca5f0d4b 352 SMART SM01232 160 255 7.8E-32 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CFK41_RS11075 f00a77405afb8af82a014f8dca5f0d4b 352 SMART SM00898 2 146 3.6E-9 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CFK41_RS11075 f00a77405afb8af82a014f8dca5f0d4b 352 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 160 245 4.9E-16 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CFK41_RS11075 f00a77405afb8af82a014f8dca5f0d4b 352 Gene3D G3DSA:1.10.8.50 155 322 1.4E-45 T 28-03-2018 CFK41_RS05795 7889471cff44e2942332f970f532486d 328 SUPERFAMILY SSF53633 34 326 4.19E-84 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CFK41_RS05795 7889471cff44e2942332f970f532486d 328 Pfam PF00696 Amino acid kinase family 54 294 1.4E-44 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CFK41_RS05795 7889471cff44e2942332f970f532486d 328 PRINTS PR00474 Glutamate 5-kinase family signature 274 294 5.8E-9 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CFK41_RS05795 7889471cff44e2942332f970f532486d 328 PRINTS PR00474 Glutamate 5-kinase family signature 223 250 5.8E-9 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CFK41_RS05795 7889471cff44e2942332f970f532486d 328 PRINTS PR00474 Glutamate 5-kinase family signature 85 99 5.8E-9 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CFK41_RS05795 7889471cff44e2942332f970f532486d 328 Gene3D G3DSA:3.40.1160.10 19 328 8.8E-74 T 28-03-2018 CFK41_RS05795 7889471cff44e2942332f970f532486d 328 TIGRFAM TIGR00761 argB: acetylglutamate kinase 56 297 3.0E-70 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CFK41_RS05795 7889471cff44e2942332f970f532486d 328 PIRSF PIRSF000728 39 324 1.9E-97 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CFK41_RS05795 7889471cff44e2942332f970f532486d 328 Hamap MF_00082_B Acetylglutamate kinase [argB]. 52 324 33.252 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CFK41_RS01780 6d906e6f89eac8db9f3cc96cad00354b 561 PIRSF PIRSF004803 12 561 4.8E-199 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CFK41_RS01780 6d906e6f89eac8db9f3cc96cad00354b 561 Hamap MF_01491 Ribonuclease J [rnj]. 14 561 38.677 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CFK41_RS01780 6d906e6f89eac8db9f3cc96cad00354b 561 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 20 558 5.5E-147 T 28-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 CFK41_RS01780 6d906e6f89eac8db9f3cc96cad00354b 561 Pfam PF00753 Metallo-beta-lactamase superfamily 28 174 1.7E-14 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS01780 6d906e6f89eac8db9f3cc96cad00354b 561 SMART SM00849 31 225 1.7E-24 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS01780 6d906e6f89eac8db9f3cc96cad00354b 561 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 370 416 5.3E-8 T 28-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CFK41_RS01780 6d906e6f89eac8db9f3cc96cad00354b 561 Gene3D G3DSA:3.60.15.10 5 457 9.4E-67 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS01780 6d906e6f89eac8db9f3cc96cad00354b 561 SUPERFAMILY SSF56281 19 433 6.86E-95 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS13535 68462812654da0934307cec664952d10 163 Gene3D G3DSA:3.40.630.30 1 159 4.0E-25 T 28-03-2018 CFK41_RS13535 68462812654da0934307cec664952d10 163 SUPERFAMILY SSF55729 2 144 4.8E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS13535 68462812654da0934307cec664952d10 163 Pfam PF00583 Acetyltransferase (GNAT) family 26 137 2.2E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS14600 0b20318161dd8a8aa3eca71018291844 447 Pfam PF00083 Sugar (and other) transporter 26 426 9.6E-21 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CFK41_RS14600 0b20318161dd8a8aa3eca71018291844 447 Gene3D G3DSA:1.20.1250.20 231 437 1.2E-19 T 28-03-2018 CFK41_RS14600 0b20318161dd8a8aa3eca71018291844 447 SUPERFAMILY SSF103473 10 430 2.75E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS14600 0b20318161dd8a8aa3eca71018291844 447 Gene3D G3DSA:1.20.1250.20 17 230 8.1E-23 T 28-03-2018 CFK41_RS08565 c728fdecedba68b432351a2afa19dd0c 902 SUPERFAMILY SSF55186 570 730 2.88E-39 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CFK41_RS08565 c728fdecedba68b432351a2afa19dd0c 902 SUPERFAMILY SSF50447 474 569 1.27E-13 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CFK41_RS08565 c728fdecedba68b432351a2afa19dd0c 902 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 671 714 3.8E-15 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CFK41_RS08565 c728fdecedba68b432351a2afa19dd0c 902 Gene3D G3DSA:3.30.980.10 571 732 6.9E-37 T 28-03-2018 CFK41_RS08565 c728fdecedba68b432351a2afa19dd0c 902 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 879 2.8E-237 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CFK41_RS08565 c728fdecedba68b432351a2afa19dd0c 902 SUPERFAMILY SSF101353 257 452 1.7E-56 T 28-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 CFK41_RS08565 c728fdecedba68b432351a2afa19dd0c 902 SMART SM00863 671 715 9.9E-17 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CFK41_RS08565 c728fdecedba68b432351a2afa19dd0c 902 PRINTS PR00980 Alanyl-tRNA synthetase signature 237 250 1.8E-27 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CFK41_RS08565 c728fdecedba68b432351a2afa19dd0c 902 PRINTS PR00980 Alanyl-tRNA synthetase signature 205 216 1.8E-27 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CFK41_RS08565 c728fdecedba68b432351a2afa19dd0c 902 PRINTS PR00980 Alanyl-tRNA synthetase signature 287 303 1.8E-27 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CFK41_RS08565 c728fdecedba68b432351a2afa19dd0c 902 PRINTS PR00980 Alanyl-tRNA synthetase signature 311 324 1.8E-27 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CFK41_RS08565 c728fdecedba68b432351a2afa19dd0c 902 PRINTS PR00980 Alanyl-tRNA synthetase signature 69 80 1.8E-27 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CFK41_RS08565 c728fdecedba68b432351a2afa19dd0c 902 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 900 154.192 T 28-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 CFK41_RS08565 c728fdecedba68b432351a2afa19dd0c 902 Pfam PF01411 tRNA synthetases class II (A) 5 573 1.0E-170 T 28-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CFK41_RS08565 c728fdecedba68b432351a2afa19dd0c 902 Gene3D G3DSA:3.30.930.10 1 253 7.1E-83 T 28-03-2018 CFK41_RS08565 c728fdecedba68b432351a2afa19dd0c 902 Pfam PF02272 DHHA1 domain 753 896 4.1E-23 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CFK41_RS08565 c728fdecedba68b432351a2afa19dd0c 902 SUPERFAMILY SSF55681 2 256 5.96E-79 T 28-03-2018 CFK41_RS08985 eb72fd57c73aef18c67a6b15a213227f 230 SUPERFAMILY SSF46955 19 91 3.53E-12 T 28-03-2018 IPR009061 Putative DNA-binding domain CFK41_RS08985 eb72fd57c73aef18c67a6b15a213227f 230 Pfam PF00376 MerR family regulatory protein 18 59 1.2E-10 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS08985 eb72fd57c73aef18c67a6b15a213227f 230 SMART SM00422 17 91 3.5E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS08985 eb72fd57c73aef18c67a6b15a213227f 230 Gene3D G3DSA:1.10.1660.10 7 215 9.3E-18 T 28-03-2018 CFK41_RS08215 24271fa61d3ba314daec66c6222caa37 744 Pfam PF04389 Peptidase family M28 124 308 2.3E-27 T 28-03-2018 IPR007484 Peptidase M28 CFK41_RS08215 24271fa61d3ba314daec66c6222caa37 744 Gene3D G3DSA:3.40.630.10 48 314 1.1E-38 T 28-03-2018 CFK41_RS08215 24271fa61d3ba314daec66c6222caa37 744 SUPERFAMILY SSF53187 53 314 5.14E-38 T 28-03-2018 CFK41_RS13100 a3b0f71186925186406347ff85d71e5c 290 Gene3D G3DSA:3.40.50.1820 32 290 2.1E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS13100 a3b0f71186925186406347ff85d71e5c 290 Pfam PF12146 Serine aminopeptidase, S33 85 186 6.1E-7 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CFK41_RS13100 a3b0f71186925186406347ff85d71e5c 290 SUPERFAMILY SSF53474 70 277 3.16E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS08690 59e807bddfdee7b1258709db135b09d1 549 SUPERFAMILY SSF48013 77 231 1.24E-30 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CFK41_RS08690 59e807bddfdee7b1258709db135b09d1 549 SUPERFAMILY SSF53335 219 537 2.39E-44 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS08690 59e807bddfdee7b1258709db135b09d1 549 Pfam PF01189 16S rRNA methyltransferase RsmB/F 333 536 1.3E-43 T 28-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CFK41_RS08690 59e807bddfdee7b1258709db135b09d1 549 Gene3D G3DSA:3.40.50.150 313 546 8.7E-43 T 28-03-2018 CFK41_RS08690 59e807bddfdee7b1258709db135b09d1 549 Gene3D G3DSA:1.10.940.10 72 217 1.2E-25 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CFK41_RS08690 59e807bddfdee7b1258709db135b09d1 549 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 340 350 4.6E-20 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CFK41_RS08690 59e807bddfdee7b1258709db135b09d1 549 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 460 476 4.6E-20 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CFK41_RS08690 59e807bddfdee7b1258709db135b09d1 549 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 304 318 4.6E-20 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CFK41_RS08690 59e807bddfdee7b1258709db135b09d1 549 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 410 422 4.6E-20 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CFK41_RS08690 59e807bddfdee7b1258709db135b09d1 549 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 520 537 4.6E-20 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CFK41_RS08690 59e807bddfdee7b1258709db135b09d1 549 Pfam PF01029 NusB family 77 198 4.1E-23 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CFK41_RS05815 ab09b45be361ad40c3d0c147652b3e3b 412 Gene3D G3DSA:3.40.50.620 3 161 7.4E-26 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS05815 ab09b45be361ad40c3d0c147652b3e3b 412 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 117 128 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CFK41_RS05815 ab09b45be361ad40c3d0c147652b3e3b 412 Gene3D G3DSA:1.20.5.470 362 394 1.6E-7 T 28-03-2018 CFK41_RS05815 ab09b45be361ad40c3d0c147652b3e3b 412 TIGRFAM TIGR00032 argG: argininosuccinate synthase 4 391 1.0E-146 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CFK41_RS05815 ab09b45be361ad40c3d0c147652b3e3b 412 SUPERFAMILY SSF69864 172 394 4.84E-84 T 28-03-2018 CFK41_RS05815 ab09b45be361ad40c3d0c147652b3e3b 412 Pfam PF00764 Arginosuccinate synthase 6 390 2.1E-178 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CFK41_RS05815 ab09b45be361ad40c3d0c147652b3e3b 412 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 8 16 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CFK41_RS05815 ab09b45be361ad40c3d0c147652b3e3b 412 Hamap MF_00005 Argininosuccinate synthase [argG]. 2 396 51.496 T 28-03-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CFK41_RS05815 ab09b45be361ad40c3d0c147652b3e3b 412 SUPERFAMILY SSF52402 3 165 7.94E-44 T 28-03-2018 CFK41_RS05815 ab09b45be361ad40c3d0c147652b3e3b 412 Gene3D G3DSA:3.90.1260.10 162 352 4.3E-78 T 28-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CFK41_RS04790 d49b6445b49cc08105373bfa35f6c6e7 446 SUPERFAMILY SSF51735 102 189 3.85E-5 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS04790 d49b6445b49cc08105373bfa35f6c6e7 446 SUPERFAMILY SSF51735 201 443 2.22E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS04790 d49b6445b49cc08105373bfa35f6c6e7 446 Gene3D G3DSA:3.40.50.720 92 192 5.7E-4 T 28-03-2018 CFK41_RS04790 d49b6445b49cc08105373bfa35f6c6e7 446 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 212 440 5.3E-46 T 28-03-2018 CFK41_RS04790 d49b6445b49cc08105373bfa35f6c6e7 446 Gene3D G3DSA:3.40.50.720 193 445 2.1E-59 T 28-03-2018 CFK41_RS04790 d49b6445b49cc08105373bfa35f6c6e7 446 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 339 367 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CFK41_RS04790 d49b6445b49cc08105373bfa35f6c6e7 446 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 206 387 1.1E-6 T 28-03-2018 CFK41_RS04790 d49b6445b49cc08105373bfa35f6c6e7 446 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 373 390 2.2E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS04790 d49b6445b49cc08105373bfa35f6c6e7 446 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 278 289 2.2E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS04790 d49b6445b49cc08105373bfa35f6c6e7 446 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 326 342 2.2E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS04790 d49b6445b49cc08105373bfa35f6c6e7 446 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 224 2.2E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS04790 d49b6445b49cc08105373bfa35f6c6e7 446 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 352 371 2.2E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS04790 d49b6445b49cc08105373bfa35f6c6e7 446 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 406 426 2.2E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS14110 f07c662922819256bb5dca3f226e3a7a 647 Gene3D G3DSA:3.20.19.10 464 521 7.2E-11 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CFK41_RS14110 f07c662922819256bb5dca3f226e3a7a 647 Gene3D G3DSA:3.20.19.10 522 647 5.9E-34 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CFK41_RS14110 f07c662922819256bb5dca3f226e3a7a 647 PRINTS PR00415 Aconitase family signature 349 362 1.8E-21 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS14110 f07c662922819256bb5dca3f226e3a7a 647 PRINTS PR00415 Aconitase family signature 110 123 1.8E-21 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS14110 f07c662922819256bb5dca3f226e3a7a 647 PRINTS PR00415 Aconitase family signature 186 199 1.8E-21 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS14110 f07c662922819256bb5dca3f226e3a7a 647 PRINTS PR00415 Aconitase family signature 124 139 1.8E-21 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS14110 f07c662922819256bb5dca3f226e3a7a 647 PRINTS PR00415 Aconitase family signature 267 281 1.8E-21 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS14110 f07c662922819256bb5dca3f226e3a7a 647 Gene3D G3DSA:3.30.499.10 270 434 1.8E-40 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS14110 f07c662922819256bb5dca3f226e3a7a 647 TIGRFAM TIGR01342 acon_putative: putative aconitate hydratase 5 645 5.9E-234 T 28-03-2018 IPR006250 Aconitase, putative CFK41_RS14110 f07c662922819256bb5dca3f226e3a7a 647 SUPERFAMILY SSF53732 1 418 5.76E-129 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS14110 f07c662922819256bb5dca3f226e3a7a 647 Gene3D G3DSA:3.40.1060.10 147 269 1.7E-33 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS14110 f07c662922819256bb5dca3f226e3a7a 647 Pfam PF00330 Aconitase family (aconitate hydratase) 8 407 4.0E-88 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS14110 f07c662922819256bb5dca3f226e3a7a 647 Pfam PF00694 Aconitase C-terminal domain 526 582 2.6E-20 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS14110 f07c662922819256bb5dca3f226e3a7a 647 SUPERFAMILY SSF52016 443 645 8.04E-49 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CFK41_RS14110 f07c662922819256bb5dca3f226e3a7a 647 Gene3D G3DSA:3.30.499.10 1 146 1.4E-38 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS01185 231d921cfd3a8878a4e4e947c355e209 317 Gene3D G3DSA:1.10.10.60 2 54 2.7E-12 T 28-03-2018 CFK41_RS01185 231d921cfd3a8878a4e4e947c355e209 317 Pfam PF04198 Putative sugar-binding domain 62 309 8.1E-45 T 28-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 CFK41_RS01185 231d921cfd3a8878a4e4e947c355e209 317 Gene3D G3DSA:3.40.50.1360 62 308 2.6E-22 T 28-03-2018 CFK41_RS01185 231d921cfd3a8878a4e4e947c355e209 317 SUPERFAMILY SSF100950 61 309 2.18E-46 T 28-03-2018 CFK41_RS07530 66a734d83ec4c325022d07a4efbfccca 510 SUPERFAMILY SSF82051 4 157 1.22E-42 T 28-03-2018 IPR006169 GTP1/OBG domain CFK41_RS07530 66a734d83ec4c325022d07a4efbfccca 510 Pfam PF01018 GTP1/OBG 5 157 6.7E-46 T 28-03-2018 IPR006169 GTP1/OBG domain CFK41_RS07530 66a734d83ec4c325022d07a4efbfccca 510 Hamap MF_01454 GTPase Obg [obg]. 3 341 42.017 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CFK41_RS07530 66a734d83ec4c325022d07a4efbfccca 510 SUPERFAMILY SSF52540 161 348 9.74E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS07530 66a734d83ec4c325022d07a4efbfccca 510 Gene3D G3DSA:3.40.50.300 159 347 1.5E-31 T 28-03-2018 CFK41_RS07530 66a734d83ec4c325022d07a4efbfccca 510 Gene3D G3DSA:2.70.210.12 3 156 7.1E-47 T 28-03-2018 IPR006169 GTP1/OBG domain CFK41_RS07530 66a734d83ec4c325022d07a4efbfccca 510 Pfam PF09269 Domain of unknown function (DUF1967) 374 442 2.2E-21 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CFK41_RS07530 66a734d83ec4c325022d07a4efbfccca 510 SUPERFAMILY SSF102741 374 444 8.76E-17 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CFK41_RS07530 66a734d83ec4c325022d07a4efbfccca 510 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 372 443 7.6E-23 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CFK41_RS07530 66a734d83ec4c325022d07a4efbfccca 510 Pfam PF01926 50S ribosome-binding GTPase 161 294 1.4E-23 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CFK41_RS07530 66a734d83ec4c325022d07a4efbfccca 510 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 4 339 3.3E-115 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CFK41_RS07530 66a734d83ec4c325022d07a4efbfccca 510 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 28-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 CFK41_RS07530 66a734d83ec4c325022d07a4efbfccca 510 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 6.1E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CFK41_RS07530 66a734d83ec4c325022d07a4efbfccca 510 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 6.1E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CFK41_RS07530 66a734d83ec4c325022d07a4efbfccca 510 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 6.1E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CFK41_RS07530 66a734d83ec4c325022d07a4efbfccca 510 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 6.1E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CFK41_RS10055 963a86bd1f09151860cc61a9b8fd41f3 455 SUPERFAMILY SSF53474 160 427 4.22E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS10055 963a86bd1f09151860cc61a9b8fd41f3 455 Gene3D G3DSA:3.40.50.1820 156 428 1.0E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS10055 963a86bd1f09151860cc61a9b8fd41f3 455 Pfam PF00326 Prolyl oligopeptidase family 245 425 1.1E-7 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CFK41_RS05760 da535a363b72d49e454bc8a1676aab1e 356 Gene3D G3DSA:3.40.50.300 21 356 3.0E-70 T 28-03-2018 CFK41_RS05760 da535a363b72d49e454bc8a1676aab1e 356 Pfam PF00005 ABC transporter 49 204 6.2E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS05760 da535a363b72d49e454bc8a1676aab1e 356 ProSitePatterns PS00211 ABC transporters family signature. 176 190 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS05760 da535a363b72d49e454bc8a1676aab1e 356 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 255 324 3.6E-16 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CFK41_RS05760 da535a363b72d49e454bc8a1676aab1e 356 SMART SM00382 58 253 1.6E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS05760 da535a363b72d49e454bc8a1676aab1e 356 SUPERFAMILY SSF52540 24 274 8.27E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS05760 da535a363b72d49e454bc8a1676aab1e 356 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 253 344 2.4E-18 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CFK41_RS17320 b487227cf8814a24f8f92eeb3e8ecc1d 96 Pfam PF14117 Domain of unknown function (DUF4287) 2 64 3.3E-20 T 28-03-2018 IPR025629 Protein of unknown function DUF4287 CFK41_RS13940 56104c06b6b0d7e460334a92d17a932e 356 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 84 280 5.7E-25 T 28-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain CFK41_RS13940 56104c06b6b0d7e460334a92d17a932e 356 Gene3D G3DSA:3.40.50.2300 190 351 2.6E-29 T 28-03-2018 CFK41_RS13940 56104c06b6b0d7e460334a92d17a932e 356 Gene3D G3DSA:1.10.260.40 27 81 1.2E-18 T 28-03-2018 CFK41_RS13940 56104c06b6b0d7e460334a92d17a932e 356 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 27 37 2.8E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS13940 56104c06b6b0d7e460334a92d17a932e 356 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 37 47 2.8E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS13940 56104c06b6b0d7e460334a92d17a932e 356 SUPERFAMILY SSF47413 25 83 3.77E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS13940 56104c06b6b0d7e460334a92d17a932e 356 SUPERFAMILY SSF53822 86 350 9.06E-49 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS13940 56104c06b6b0d7e460334a92d17a932e 356 ProSitePatterns PS00356 LacI-type HTH domain signature. 28 46 - T 28-03-2018 CFK41_RS13940 56104c06b6b0d7e460334a92d17a932e 356 Pfam PF00356 Bacterial regulatory proteins, lacI family 27 72 6.8E-16 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS13940 56104c06b6b0d7e460334a92d17a932e 356 SMART SM00354 25 95 5.5E-22 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS13940 56104c06b6b0d7e460334a92d17a932e 356 Gene3D G3DSA:3.40.50.2300 82 189 2.3E-31 T 28-03-2018 CFK41_RS11580 bb55391b1feb3f71ced5de04ad674048 160 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 144 2.3E-45 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CFK41_RS11580 bb55391b1feb3f71ced5de04ad674048 160 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 150 74.369 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CFK41_RS11580 bb55391b1feb3f71ced5de04ad674048 160 Pfam PF03477 ATP cone domain 47 129 3.7E-12 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CFK41_RS00995 106c7c0fe463a761193dab54fc248849 110 SMART SM00418 11 89 1.5E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS00995 106c7c0fe463a761193dab54fc248849 110 Gene3D G3DSA:1.10.10.10 1 110 3.5E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS00995 106c7c0fe463a761193dab54fc248849 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 8.3E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS00995 106c7c0fe463a761193dab54fc248849 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 8.3E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS00995 106c7c0fe463a761193dab54fc248849 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 8.3E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS00995 106c7c0fe463a761193dab54fc248849 110 SUPERFAMILY SSF46785 6 101 5.92E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS00995 106c7c0fe463a761193dab54fc248849 110 Pfam PF12840 Helix-turn-helix domain 11 69 1.8E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS12770 bdf222aacb825f8ff9f538e9a9dad54f 321 SUPERFAMILY SSF161098 94 303 3.92E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS12770 bdf222aacb825f8ff9f538e9a9dad54f 321 Gene3D G3DSA:1.10.3720.10 2 308 2.4E-34 T 28-03-2018 CFK41_RS12770 bdf222aacb825f8ff9f538e9a9dad54f 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 319 1.2E-34 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS11565 53ec6c2d1f666a05f4cf427a2b88f6df 67 SMART SM00357 3 67 5.7E-28 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CFK41_RS11565 53ec6c2d1f666a05f4cf427a2b88f6df 67 PIRSF PIRSF002599 1 67 7.0E-26 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CFK41_RS11565 53ec6c2d1f666a05f4cf427a2b88f6df 67 Gene3D G3DSA:2.40.50.140 1 67 3.3E-28 T 28-03-2018 CFK41_RS11565 53ec6c2d1f666a05f4cf427a2b88f6df 67 PRINTS PR00050 Cold shock protein signature 25 34 3.0E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CFK41_RS11565 53ec6c2d1f666a05f4cf427a2b88f6df 67 PRINTS PR00050 Cold shock protein signature 4 19 3.0E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CFK41_RS11565 53ec6c2d1f666a05f4cf427a2b88f6df 67 PRINTS PR00050 Cold shock protein signature 40 58 3.0E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CFK41_RS11565 53ec6c2d1f666a05f4cf427a2b88f6df 67 SUPERFAMILY SSF50249 1 66 7.68E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS11565 53ec6c2d1f666a05f4cf427a2b88f6df 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 28-03-2018 IPR019844 Cold-shock conserved site CFK41_RS11565 53ec6c2d1f666a05f4cf427a2b88f6df 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 5.7E-30 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CFK41_RS14555 8ae46e1094fbcd30d4a752932a63211f 378 Gene3D G3DSA:3.30.390.10 1 112 1.1E-31 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS14555 8ae46e1094fbcd30d4a752932a63211f 378 SMART SM00922 130 237 4.3E-10 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CFK41_RS14555 8ae46e1094fbcd30d4a752932a63211f 378 Gene3D G3DSA:3.20.20.120 113 361 7.4E-61 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS14555 8ae46e1094fbcd30d4a752932a63211f 378 SUPERFAMILY SSF51604 98 356 7.99E-67 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS14555 8ae46e1094fbcd30d4a752932a63211f 378 SUPERFAMILY SSF54826 1 115 8.46E-27 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS14555 8ae46e1094fbcd30d4a752932a63211f 378 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 12 110 1.0E-16 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CFK41_RS14555 8ae46e1094fbcd30d4a752932a63211f 378 Pfam PF13378 Enolase C-terminal domain-like 133 353 1.2E-51 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS07440 8f6265a9883397b16c57af2b2bd58271 193 Gene3D G3DSA:3.40.630.30 4 192 9.1E-30 T 28-03-2018 CFK41_RS07440 8f6265a9883397b16c57af2b2bd58271 193 Pfam PF13302 Acetyltransferase (GNAT) domain 16 155 3.6E-24 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS07440 8f6265a9883397b16c57af2b2bd58271 193 SUPERFAMILY SSF55729 13 181 8.07E-34 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS17615 4bc6b206a2694d5ac283c90d025fbe38 397 Gene3D G3DSA:1.20.1250.20 208 397 2.3E-13 T 28-03-2018 CFK41_RS17615 4bc6b206a2694d5ac283c90d025fbe38 397 SUPERFAMILY SSF103473 6 392 1.7E-29 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS17615 4bc6b206a2694d5ac283c90d025fbe38 397 Gene3D G3DSA:1.20.1250.20 4 200 2.1E-12 T 28-03-2018 CFK41_RS17615 4bc6b206a2694d5ac283c90d025fbe38 397 Pfam PF07690 Major Facilitator Superfamily 12 248 2.0E-16 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS09240 27562ca186075d6a6d7ec26902acefba 298 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 15 297 38.061 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CFK41_RS09240 27562ca186075d6a6d7ec26902acefba 298 SUPERFAMILY SSF52540 14 164 1.72E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS09240 27562ca186075d6a6d7ec26902acefba 298 Gene3D G3DSA:3.40.50.300 8 170 3.4E-9 T 28-03-2018 CFK41_RS09240 27562ca186075d6a6d7ec26902acefba 298 PIRSF PIRSF005052 15 298 1.4E-98 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CFK41_RS09240 27562ca186075d6a6d7ec26902acefba 298 Pfam PF03668 P-loop ATPase protein family 16 298 2.4E-97 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CFK41_RS01250 2f0143f8a637db12b1dd4cbc913663cf 426 Gene3D G3DSA:1.20.140.10 243 419 7.6E-23 T 28-03-2018 CFK41_RS01250 2f0143f8a637db12b1dd4cbc913663cf 426 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 152 230 9.5E-9 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CFK41_RS01250 2f0143f8a637db12b1dd4cbc913663cf 426 Gene3D G3DSA:2.40.110.10 144 242 4.1E-19 T 28-03-2018 CFK41_RS01250 2f0143f8a637db12b1dd4cbc913663cf 426 PIRSF PIRSF016578 22 103 1.3E-8 T 28-03-2018 CFK41_RS01250 2f0143f8a637db12b1dd4cbc913663cf 426 PIRSF PIRSF016578 131 410 1.2E-24 T 28-03-2018 CFK41_RS01250 2f0143f8a637db12b1dd4cbc913663cf 426 SUPERFAMILY SSF47203 244 400 6.44E-17 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CFK41_RS01250 2f0143f8a637db12b1dd4cbc913663cf 426 SUPERFAMILY SSF56645 40 238 2.62E-41 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CFK41_RS01250 2f0143f8a637db12b1dd4cbc913663cf 426 Gene3D G3DSA:1.10.540.10 27 143 1.6E-8 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CFK41_RS01250 2f0143f8a637db12b1dd4cbc913663cf 426 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 264 394 2.8E-17 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CFK41_RS09330 f6ac7e750bc4dcd1eb47ea14b01bfb3e 440 Gene3D G3DSA:2.60.40.1180 338 436 2.8E-13 T 28-03-2018 CFK41_RS09330 f6ac7e750bc4dcd1eb47ea14b01bfb3e 440 Gene3D G3DSA:3.20.20.80 11 337 7.0E-93 T 28-03-2018 CFK41_RS09330 f6ac7e750bc4dcd1eb47ea14b01bfb3e 440 PRINTS PR00741 Glycosyl hydrolase family 29 signature 128 147 4.1E-21 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS09330 f6ac7e750bc4dcd1eb47ea14b01bfb3e 440 PRINTS PR00741 Glycosyl hydrolase family 29 signature 282 303 4.1E-21 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS09330 f6ac7e750bc4dcd1eb47ea14b01bfb3e 440 PRINTS PR00741 Glycosyl hydrolase family 29 signature 315 337 4.1E-21 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS09330 f6ac7e750bc4dcd1eb47ea14b01bfb3e 440 PRINTS PR00741 Glycosyl hydrolase family 29 signature 84 100 4.1E-21 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS09330 f6ac7e750bc4dcd1eb47ea14b01bfb3e 440 SUPERFAMILY SSF51445 13 332 6.11E-97 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS09330 f6ac7e750bc4dcd1eb47ea14b01bfb3e 440 PIRSF PIRSF001092 4 423 3.0E-108 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS09330 f6ac7e750bc4dcd1eb47ea14b01bfb3e 440 Pfam PF01120 Alpha-L-fucosidase 19 328 8.7E-83 T 28-03-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS09330 f6ac7e750bc4dcd1eb47ea14b01bfb3e 440 SMART SM00812 9 372 1.5E-111 T 28-03-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS16500 02f0559ae4e0160441bda11502f40b32 362 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 48 143 2.0E-7 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS16500 02f0559ae4e0160441bda11502f40b32 362 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 158 260 2.9E-6 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CFK41_RS16500 02f0559ae4e0160441bda11502f40b32 362 Gene3D G3DSA:3.40.50.720 33 155 4.6E-17 T 28-03-2018 CFK41_RS16500 02f0559ae4e0160441bda11502f40b32 362 SUPERFAMILY SSF51735 46 172 1.45E-21 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS16500 02f0559ae4e0160441bda11502f40b32 362 Gene3D G3DSA:3.30.360.10 156 358 8.8E-30 T 28-03-2018 CFK41_RS16500 02f0559ae4e0160441bda11502f40b32 362 SUPERFAMILY SSF55347 155 321 4.74E-24 T 28-03-2018 CFK41_RS05070 459e6470955fafcd52edaf9df18f66b1 195 SUPERFAMILY SSF55729 13 172 1.43E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS05070 459e6470955fafcd52edaf9df18f66b1 195 Gene3D G3DSA:3.40.630.30 2 187 1.3E-25 T 28-03-2018 CFK41_RS05070 459e6470955fafcd52edaf9df18f66b1 195 Pfam PF00583 Acetyltransferase (GNAT) family 50 167 5.5E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS09670 74476038283f190d441fe3966998061b 440 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 362 437 1.4E-12 T 28-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CFK41_RS09670 74476038283f190d441fe3966998061b 440 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 420 430 - T 28-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site CFK41_RS09670 74476038283f190d441fe3966998061b 440 Gene3D G3DSA:3.40.50.150 90 436 2.9E-37 T 28-03-2018 CFK41_RS09670 74476038283f190d441fe3966998061b 440 SUPERFAMILY SSF50249 17 69 6.85E-8 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS09670 74476038283f190d441fe3966998061b 440 SUPERFAMILY SSF53335 94 437 8.36E-41 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS09670 74476038283f190d441fe3966998061b 440 Gene3D G3DSA:2.40.50.140 5 75 4.2E-15 T 28-03-2018 CFK41_RS11970 216b16850fa70edb091faf9c34dc80e7 141 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 118 126 - T 28-03-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CFK41_RS11970 216b16850fa70edb091faf9c34dc80e7 141 Gene3D G3DSA:3.30.70.141 1 55 1.8E-17 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CFK41_RS11970 216b16850fa70edb091faf9c34dc80e7 141 Gene3D G3DSA:3.30.70.141 56 140 3.9E-29 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CFK41_RS11970 216b16850fa70edb091faf9c34dc80e7 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 118 137 2.5E-33 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CFK41_RS11970 216b16850fa70edb091faf9c34dc80e7 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 2.5E-33 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CFK41_RS11970 216b16850fa70edb091faf9c34dc80e7 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 2.5E-33 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CFK41_RS11970 216b16850fa70edb091faf9c34dc80e7 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 2.5E-33 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CFK41_RS11970 216b16850fa70edb091faf9c34dc80e7 141 SUPERFAMILY SSF54919 1 140 5.89E-48 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CFK41_RS11970 216b16850fa70edb091faf9c34dc80e7 141 Pfam PF00334 Nucleoside diphosphate kinase 4 139 9.2E-47 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CFK41_RS11970 216b16850fa70edb091faf9c34dc80e7 141 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 140 29.317 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CFK41_RS11970 216b16850fa70edb091faf9c34dc80e7 141 SMART SM00562 3 141 1.3E-60 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CFK41_RS01325 a891f99354b83cfb00a287806aca0f9a 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 303 3.1E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01325 a891f99354b83cfb00a287806aca0f9a 305 Gene3D G3DSA:1.10.3720.10 26 292 5.5E-30 T 28-03-2018 CFK41_RS01325 a891f99354b83cfb00a287806aca0f9a 305 SUPERFAMILY SSF161098 98 283 1.27E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS03625 cc9c9ac9a9d3ed77ed6dff051c0a21de 108 SMART SM00450 1 96 3.7E-14 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS03625 cc9c9ac9a9d3ed77ed6dff051c0a21de 108 SUPERFAMILY SSF52821 13 99 3.4E-25 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS03625 cc9c9ac9a9d3ed77ed6dff051c0a21de 108 Pfam PF00581 Rhodanese-like domain 15 92 1.7E-9 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS03625 cc9c9ac9a9d3ed77ed6dff051c0a21de 108 Gene3D G3DSA:3.40.250.10 2 102 3.4E-21 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS13170 a03b9966c08c33ba1917244af03f72ba 325 SMART SM00829 14 323 3.1E-8 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CFK41_RS13170 a03b9966c08c33ba1917244af03f72ba 325 Gene3D G3DSA:3.40.50.720 138 263 8.5E-19 T 28-03-2018 CFK41_RS13170 a03b9966c08c33ba1917244af03f72ba 325 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 90 4.9E-9 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CFK41_RS13170 a03b9966c08c33ba1917244af03f72ba 325 SUPERFAMILY SSF51735 114 290 4.06E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS13170 a03b9966c08c33ba1917244af03f72ba 325 Gene3D G3DSA:3.90.180.10 1 137 3.4E-35 T 28-03-2018 CFK41_RS13170 a03b9966c08c33ba1917244af03f72ba 325 SUPERFAMILY SSF50129 1 144 1.57E-31 T 28-03-2018 IPR011032 GroES-like CFK41_RS13170 a03b9966c08c33ba1917244af03f72ba 325 Pfam PF00107 Zinc-binding dehydrogenase 151 266 1.7E-16 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CFK41_RS14540 1fd969b84fde5ee67c781cd52c278bb8 221 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 1.8E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS14540 1fd969b84fde5ee67c781cd52c278bb8 221 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 1.8E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS14540 1fd969b84fde5ee67c781cd52c278bb8 221 SUPERFAMILY SSF46785 17 106 4.46E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS14540 1fd969b84fde5ee67c781cd52c278bb8 221 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 80 7.3E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS14540 1fd969b84fde5ee67c781cd52c278bb8 221 Pfam PF07729 FCD domain 91 207 2.7E-21 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS14540 1fd969b84fde5ee67c781cd52c278bb8 221 Gene3D G3DSA:1.20.120.530 78 221 4.4E-30 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS14540 1fd969b84fde5ee67c781cd52c278bb8 221 SUPERFAMILY SSF48008 86 215 2.2E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS14540 1fd969b84fde5ee67c781cd52c278bb8 221 SMART SM00345 22 80 2.7E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS14540 1fd969b84fde5ee67c781cd52c278bb8 221 SMART SM00895 90 209 4.8E-15 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS14540 1fd969b84fde5ee67c781cd52c278bb8 221 Gene3D G3DSA:1.10.10.10 5 77 4.8E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS08655 28417137fe9fb33a9be7da6c0ed3f34c 62 Hamap MF_02106 Prokaryotic ubiquitin-like protein Pup [pup]. 1 62 15.466 T 28-03-2018 IPR008515 Ubiquitin-like, Pup CFK41_RS08655 28417137fe9fb33a9be7da6c0ed3f34c 62 TIGRFAM TIGR03687 pupylate_cterm: ubiquitin-like protein Pup 31 62 2.7E-20 T 28-03-2018 IPR008515 Ubiquitin-like, Pup CFK41_RS08655 28417137fe9fb33a9be7da6c0ed3f34c 62 Pfam PF05639 Pup-like protein 16 62 1.6E-18 T 28-03-2018 IPR008515 Ubiquitin-like, Pup CFK41_RS16505 e92399c76fe3cb79ce5e8c25264165fa 903 PRINTS PR00132 Glycosyl hydrolase family 2 signature 370 384 2.1E-13 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CFK41_RS16505 e92399c76fe3cb79ce5e8c25264165fa 903 PRINTS PR00132 Glycosyl hydrolase family 2 signature 471 486 2.1E-13 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CFK41_RS16505 e92399c76fe3cb79ce5e8c25264165fa 903 PRINTS PR00132 Glycosyl hydrolase family 2 signature 401 419 2.1E-13 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CFK41_RS16505 e92399c76fe3cb79ce5e8c25264165fa 903 PRINTS PR00132 Glycosyl hydrolase family 2 signature 161 176 2.1E-13 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CFK41_RS16505 e92399c76fe3cb79ce5e8c25264165fa 903 Gene3D G3DSA:2.60.40.10 773 886 2.2E-10 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS16505 e92399c76fe3cb79ce5e8c25264165fa 903 Gene3D G3DSA:2.60.40.10 694 772 7.9E-24 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS16505 e92399c76fe3cb79ce5e8c25264165fa 903 Gene3D G3DSA:3.20.20.80 608 691 3.7E-16 T 28-03-2018 CFK41_RS16505 e92399c76fe3cb79ce5e8c25264165fa 903 Gene3D G3DSA:3.20.20.80 360 607 1.1E-39 T 28-03-2018 CFK41_RS16505 e92399c76fe3cb79ce5e8c25264165fa 903 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 365 520 3.6E-25 T 28-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 CFK41_RS16505 e92399c76fe3cb79ce5e8c25264165fa 903 Pfam PF00703 Glycosyl hydrolases family 2 239 358 3.9E-9 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CFK41_RS16505 e92399c76fe3cb79ce5e8c25264165fa 903 SUPERFAMILY SSF49785 94 250 2.41E-38 T 28-03-2018 IPR008979 Galactose-binding domain-like CFK41_RS16505 e92399c76fe3cb79ce5e8c25264165fa 903 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 105 227 1.1E-10 T 28-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CFK41_RS16505 e92399c76fe3cb79ce5e8c25264165fa 903 Gene3D G3DSA:2.60.120.260 3 227 2.6E-35 T 28-03-2018 IPR008979 Galactose-binding domain-like CFK41_RS16505 e92399c76fe3cb79ce5e8c25264165fa 903 Gene3D G3DSA:2.60.40.10 228 359 4.3E-19 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS16505 e92399c76fe3cb79ce5e8c25264165fa 903 SUPERFAMILY SSF51445 355 688 6.63E-73 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS16505 e92399c76fe3cb79ce5e8c25264165fa 903 Pfam PF16355 Domain of unknown function (DUF4982) 707 768 1.3E-18 T 28-03-2018 IPR032311 Domain of unknown function DUF4982 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CFK41_RS16505 e92399c76fe3cb79ce5e8c25264165fa 903 SUPERFAMILY SSF49303 239 358 7.19E-11 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CFK41_RS11930 bb174940e60acd334c4342ba5282635c 376 Gene3D G3DSA:2.30.40.10 18 76 4.7E-4 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS11930 bb174940e60acd334c4342ba5282635c 376 SUPERFAMILY SSF51338 332 373 3.21E-5 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS11930 bb174940e60acd334c4342ba5282635c 376 SUPERFAMILY SSF51556 62 337 2.09E-48 T 28-03-2018 IPR032466 Metal-dependent hydrolase CFK41_RS11930 bb174940e60acd334c4342ba5282635c 376 Pfam PF01979 Amidohydrolase family 182 372 1.9E-7 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CFK41_RS11930 bb174940e60acd334c4342ba5282635c 376 Gene3D G3DSA:3.20.20.140 77 337 5.8E-28 T 28-03-2018 CFK41_RS17585 7e6a1ace05a06767670759d3fbbb0937 460 SUPERFAMILY SSF53383 102 458 3.89E-67 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS17585 7e6a1ace05a06767670759d3fbbb0937 460 Pfam PF00155 Aminotransferase class I and II 122 455 3.3E-25 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CFK41_RS17585 7e6a1ace05a06767670759d3fbbb0937 460 Gene3D G3DSA:1.10.10.10 17 88 4.0E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS17585 7e6a1ace05a06767670759d3fbbb0937 460 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 60 3.7E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS17585 7e6a1ace05a06767670759d3fbbb0937 460 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 60 76 3.7E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS17585 7e6a1ace05a06767670759d3fbbb0937 460 Gene3D G3DSA:3.90.1150.10 373 458 1.2E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS17585 7e6a1ace05a06767670759d3fbbb0937 460 SUPERFAMILY SSF46785 17 90 6.41E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS17585 7e6a1ace05a06767670759d3fbbb0937 460 SMART SM00345 27 86 1.7E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS17585 7e6a1ace05a06767670759d3fbbb0937 460 Gene3D G3DSA:3.40.640.10 129 372 3.7E-35 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS17585 7e6a1ace05a06767670759d3fbbb0937 460 Pfam PF00392 Bacterial regulatory proteins, gntR family 27 86 6.7E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS16955 8e3e5a37add3b9b6c5b1523b18db15f1 374 Gene3D G3DSA:3.30.360.10 130 372 1.5E-44 T 28-03-2018 CFK41_RS16955 8e3e5a37add3b9b6c5b1523b18db15f1 374 Gene3D G3DSA:3.40.50.720 1 129 6.5E-32 T 28-03-2018 CFK41_RS16955 8e3e5a37add3b9b6c5b1523b18db15f1 374 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 130 207 8.9E-11 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CFK41_RS16955 8e3e5a37add3b9b6c5b1523b18db15f1 374 SUPERFAMILY SSF51735 2 148 9.08E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS16955 8e3e5a37add3b9b6c5b1523b18db15f1 374 SUPERFAMILY SSF55347 122 299 8.67E-34 T 28-03-2018 CFK41_RS16955 8e3e5a37add3b9b6c5b1523b18db15f1 374 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 118 8.1E-19 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS16005 0d1fa4f9dcdac97a7667c41af8ea7a1b 243 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 214 226 1.2E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS16005 0d1fa4f9dcdac97a7667c41af8ea7a1b 243 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 198 1.2E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS16005 0d1fa4f9dcdac97a7667c41af8ea7a1b 243 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 198 214 1.2E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS16005 0d1fa4f9dcdac97a7667c41af8ea7a1b 243 SMART SM00421 181 238 2.1E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS16005 0d1fa4f9dcdac97a7667c41af8ea7a1b 243 ProSitePatterns PS00622 LuxR-type HTH domain signature. 198 225 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS16005 0d1fa4f9dcdac97a7667c41af8ea7a1b 243 Pfam PF00072 Response regulator receiver domain 21 132 1.5E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS16005 0d1fa4f9dcdac97a7667c41af8ea7a1b 243 SMART SM00448 19 132 6.4E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS16005 0d1fa4f9dcdac97a7667c41af8ea7a1b 243 SUPERFAMILY SSF46894 174 242 1.36E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CFK41_RS16005 0d1fa4f9dcdac97a7667c41af8ea7a1b 243 SUPERFAMILY SSF52172 19 142 1.85E-33 T 28-03-2018 IPR011006 CheY-like superfamily CFK41_RS16005 0d1fa4f9dcdac97a7667c41af8ea7a1b 243 Gene3D G3DSA:1.10.10.10 144 243 1.0E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS16005 0d1fa4f9dcdac97a7667c41af8ea7a1b 243 Gene3D G3DSA:3.40.50.2300 18 143 8.4E-37 T 28-03-2018 CFK41_RS16005 0d1fa4f9dcdac97a7667c41af8ea7a1b 243 Pfam PF00196 Bacterial regulatory proteins, luxR family 185 236 1.6E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS07410 0ee27c17a5655e5cf77b8e437c717c74 247 Gene3D G3DSA:3.40.50.880 3 244 2.7E-41 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS07410 0ee27c17a5655e5cf77b8e437c717c74 247 SUPERFAMILY SSF52317 39 216 1.37E-25 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS07410 0ee27c17a5655e5cf77b8e437c717c74 247 Pfam PF03575 Peptidase family S51 44 213 2.1E-29 T 28-03-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 CFK41_RS14845 aabacb4ca2dec1d51004a00c1bfe111e 314 SUPERFAMILY SSF53850 86 288 7.35E-42 T 28-03-2018 CFK41_RS14845 aabacb4ca2dec1d51004a00c1bfe111e 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.6E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CFK41_RS14845 aabacb4ca2dec1d51004a00c1bfe111e 314 Gene3D G3DSA:3.40.190.10 88 179 6.3E-27 T 28-03-2018 CFK41_RS14845 aabacb4ca2dec1d51004a00c1bfe111e 314 Gene3D G3DSA:3.40.190.10 180 264 1.5E-23 T 28-03-2018 CFK41_RS14845 aabacb4ca2dec1d51004a00c1bfe111e 314 SUPERFAMILY SSF46785 1 82 5.99E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS14845 aabacb4ca2dec1d51004a00c1bfe111e 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.0E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CFK41_RS14845 aabacb4ca2dec1d51004a00c1bfe111e 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.0E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CFK41_RS14845 aabacb4ca2dec1d51004a00c1bfe111e 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.0E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CFK41_RS14845 aabacb4ca2dec1d51004a00c1bfe111e 314 Pfam PF03466 LysR substrate binding domain 88 287 2.5E-46 T 28-03-2018 IPR005119 LysR, substrate-binding CFK41_RS14845 aabacb4ca2dec1d51004a00c1bfe111e 314 Gene3D G3DSA:1.10.10.10 1 83 9.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS13620 e2cbfe157194eaef09f189bc7dee36e1 139 PIRSF PIRSF028777 5 133 6.7E-48 T 28-03-2018 IPR031308 Uncharacterised conserved protein UCP028777 CFK41_RS13620 e2cbfe157194eaef09f189bc7dee36e1 139 Pfam PF03733 Inner membrane component domain 8 58 1.7E-15 T 28-03-2018 IPR005185 Inner membrane component domain CFK41_RS13620 e2cbfe157194eaef09f189bc7dee36e1 139 Pfam PF03733 Inner membrane component domain 72 122 7.2E-16 T 28-03-2018 IPR005185 Inner membrane component domain CFK41_RS06495 f2790177f515f5d9fe887d3f88e513ea 371 Pfam PF00005 ABC transporter 20 166 5.6E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS06495 f2790177f515f5d9fe887d3f88e513ea 371 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 212 7.8E-80 T 28-03-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 CFK41_RS06495 f2790177f515f5d9fe887d3f88e513ea 371 SUPERFAMILY SSF52540 1 222 1.64E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS06495 f2790177f515f5d9fe887d3f88e513ea 371 Gene3D G3DSA:3.40.50.300 1 353 3.8E-67 T 28-03-2018 CFK41_RS06495 f2790177f515f5d9fe887d3f88e513ea 371 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS06495 f2790177f515f5d9fe887d3f88e513ea 371 SMART SM00382 28 216 5.7E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS10215 5c3e1442c18aedfebb5672d3e2f67c34 201 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 3 178 24.863 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CFK41_RS10215 5c3e1442c18aedfebb5672d3e2f67c34 201 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 4 89 7.0E-24 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CFK41_RS10215 5c3e1442c18aedfebb5672d3e2f67c34 201 Pfam PF01386 Ribosomal L25p family 5 90 3.0E-24 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CFK41_RS10215 5c3e1442c18aedfebb5672d3e2f67c34 201 SUPERFAMILY SSF50715 10 178 1.36E-44 T 28-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CFK41_RS10215 5c3e1442c18aedfebb5672d3e2f67c34 201 Gene3D G3DSA:2.170.120.20 97 182 1.0E-17 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain CFK41_RS10215 5c3e1442c18aedfebb5672d3e2f67c34 201 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 98 178 4.1E-15 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain CFK41_RS10215 5c3e1442c18aedfebb5672d3e2f67c34 201 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 5 175 3.1E-39 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CFK41_RS10215 5c3e1442c18aedfebb5672d3e2f67c34 201 Gene3D G3DSA:2.40.240.10 3 92 7.1E-26 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CFK41_RS05725 f1966e27199b24492eb122c202745e79 366 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 148 1.9E-26 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CFK41_RS05725 f1966e27199b24492eb122c202745e79 366 Pfam PF00107 Zinc-binding dehydrogenase 190 325 1.4E-24 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CFK41_RS05725 f1966e27199b24492eb122c202745e79 366 Gene3D G3DSA:3.40.50.720 190 310 5.2E-20 T 28-03-2018 CFK41_RS05725 f1966e27199b24492eb122c202745e79 366 TIGRFAM TIGR03451 mycoS_dep_FDH: S-(hydroxymethyl)mycothiol dehydrogenase 4 363 7.3E-183 T 28-03-2018 IPR017816 S-(hydroxymethyl)mycothiol dehydrogenase KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.30 CFK41_RS05725 f1966e27199b24492eb122c202745e79 366 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CFK41_RS05725 f1966e27199b24492eb122c202745e79 366 SUPERFAMILY SSF51735 152 330 5.05E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS05725 f1966e27199b24492eb122c202745e79 366 SUPERFAMILY SSF50129 314 362 8.0E-6 T 28-03-2018 IPR011032 GroES-like CFK41_RS05725 f1966e27199b24492eb122c202745e79 366 Gene3D G3DSA:3.90.180.10 2 189 8.7E-46 T 28-03-2018 CFK41_RS05725 f1966e27199b24492eb122c202745e79 366 SUPERFAMILY SSF50129 3 186 2.43E-51 T 28-03-2018 IPR011032 GroES-like CFK41_RS16610 7c03ce2b81500538d3bc19d474c3d91c 191 SUPERFAMILY SSF109854 6 170 5.65E-25 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CFK41_RS16610 7c03ce2b81500538d3bc19d474c3d91c 191 Gene3D G3DSA:1.20.120.450 5 175 5.7E-24 T 28-03-2018 CFK41_RS16610 7c03ce2b81500538d3bc19d474c3d91c 191 Pfam PF04978 Protein of unknown function (DUF664) 15 171 9.4E-31 T 28-03-2018 IPR007061 Protein of unknown function DUF664 CFK41_RS02470 368947b5efe60b9939258d9a44259cd4 727 Gene3D G3DSA:2.120.10.30 63 281 1.2E-11 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CFK41_RS02470 368947b5efe60b9939258d9a44259cd4 727 Gene3D G3DSA:2.120.10.30 296 596 3.7E-4 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CFK41_RS02470 368947b5efe60b9939258d9a44259cd4 727 SUPERFAMILY SSF63829 122 324 2.75E-12 T 28-03-2018 CFK41_RS02470 368947b5efe60b9939258d9a44259cd4 727 SUPERFAMILY SSF50998 584 715 2.2E-9 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CFK41_RS02470 368947b5efe60b9939258d9a44259cd4 727 SUPERFAMILY SSF50998 387 682 1.36E-7 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CFK41_RS02470 368947b5efe60b9939258d9a44259cd4 727 Gene3D G3DSA:2.140.10.10 597 725 3.4E-7 T 28-03-2018 CFK41_RS09920 8124ce086e60f3314c34f6ee4bdab3af 458 SUPERFAMILY SSF52954 353 429 5.73E-11 T 28-03-2018 IPR004154 Anticodon-binding CFK41_RS09920 8124ce086e60f3314c34f6ee4bdab3af 458 Gene3D G3DSA:3.30.930.10 1 349 7.5E-75 T 28-03-2018 CFK41_RS09920 8124ce086e60f3314c34f6ee4bdab3af 458 Pfam PF03129 Anticodon binding domain 356 423 1.1E-5 T 28-03-2018 IPR004154 Anticodon-binding CFK41_RS09920 8124ce086e60f3314c34f6ee4bdab3af 458 PIRSF PIRSF001549 1 442 1.5E-97 T 28-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CFK41_RS09920 8124ce086e60f3314c34f6ee4bdab3af 458 Pfam PF13393 Histidyl-tRNA synthetase 9 336 3.9E-29 T 28-03-2018 CFK41_RS09920 8124ce086e60f3314c34f6ee4bdab3af 458 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 6 430 3.6E-104 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CFK41_RS09920 8124ce086e60f3314c34f6ee4bdab3af 458 SUPERFAMILY SSF55681 6 341 2.79E-62 T 28-03-2018 CFK41_RS09920 8124ce086e60f3314c34f6ee4bdab3af 458 Gene3D G3DSA:3.40.50.800 351 437 1.9E-13 T 28-03-2018 IPR004154 Anticodon-binding CFK41_RS14520 17f0a325e0b4341c4f46629e6736ffbd 357 SUPERFAMILY SSF50331 240 357 2.92E-21 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CFK41_RS14520 17f0a325e0b4341c4f46629e6736ffbd 357 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS14520 17f0a325e0b4341c4f46629e6736ffbd 357 SUPERFAMILY SSF52540 4 245 2.48E-81 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS14520 17f0a325e0b4341c4f46629e6736ffbd 357 Gene3D G3DSA:2.40.50.100 245 291 4.9E-5 T 28-03-2018 CFK41_RS14520 17f0a325e0b4341c4f46629e6736ffbd 357 Pfam PF08402 TOBE domain 279 349 2.7E-6 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CFK41_RS14520 17f0a325e0b4341c4f46629e6736ffbd 357 SMART SM00382 31 214 1.2E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS14520 17f0a325e0b4341c4f46629e6736ffbd 357 Gene3D G3DSA:3.40.50.300 2 244 5.2E-71 T 28-03-2018 CFK41_RS14520 17f0a325e0b4341c4f46629e6736ffbd 357 Pfam PF00005 ABC transporter 23 164 6.9E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS14520 17f0a325e0b4341c4f46629e6736ffbd 357 Gene3D G3DSA:2.40.50.140 292 342 2.7E-9 T 28-03-2018 CFK41_RS13640 31c0b9246b5d7a12da94b043c64bfb70 257 Gene3D G3DSA:3.40.50.1580 21 254 2.8E-36 T 28-03-2018 CFK41_RS13640 31c0b9246b5d7a12da94b043c64bfb70 257 SUPERFAMILY SSF53167 22 250 4.45E-42 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CFK41_RS13640 31c0b9246b5d7a12da94b043c64bfb70 257 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 24 251 3.5E-36 T 28-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CFK41_RS13640 31c0b9246b5d7a12da94b043c64bfb70 257 Pfam PF01048 Phosphorylase superfamily 22 251 1.9E-31 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CFK41_RS10785 50d715c83cffd5a95be419c57209751e 514 Pfam PF17173 Domain of unknown function (DUF5129) 52 401 1.4E-61 T 28-03-2018 IPR033435 Domain of unknown function DUF5129 CFK41_RS10785 50d715c83cffd5a95be419c57209751e 514 Gene3D G3DSA:3.40.50.300 42 453 0.0013 T 28-03-2018 CFK41_RS16545 9d2ba6aa170d8dd7fc4623d0e83beff5 217 SUPERFAMILY SSF51569 10 209 1.08E-50 T 28-03-2018 CFK41_RS16545 9d2ba6aa170d8dd7fc4623d0e83beff5 217 Gene3D G3DSA:3.20.20.70 8 214 8.9E-30 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS16545 9d2ba6aa170d8dd7fc4623d0e83beff5 217 Pfam PF01081 KDPG and KHG aldolase 14 190 2.1E-35 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CFK41_RS04140 361a88c7caa5fff68f661b77b9c30006 309 Gene3D G3DSA:3.90.1200.10 110 283 3.4E-9 T 28-03-2018 CFK41_RS04140 361a88c7caa5fff68f661b77b9c30006 309 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 40 286 5.8E-32 T 28-03-2018 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 CFK41_RS04140 361a88c7caa5fff68f661b77b9c30006 309 SUPERFAMILY SSF56112 34 286 4.52E-23 T 28-03-2018 IPR011009 Protein kinase-like domain CFK41_RS11575 f81f6b33752b5d317a335b103b8277ac 747 SUPERFAMILY SSF52540 179 258 3.03E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11575 f81f6b33752b5d317a335b103b8277ac 747 SUPERFAMILY SSF52540 469 740 3.03E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11575 f81f6b33752b5d317a335b103b8277ac 747 Gene3D G3DSA:3.40.50.300 185 579 8.1E-32 T 28-03-2018 CFK41_RS11575 f81f6b33752b5d317a335b103b8277ac 747 SMART SM00382 199 587 0.0046 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS11575 f81f6b33752b5d317a335b103b8277ac 747 Pfam PF13538 UvrD-like helicase C-terminal domain 689 736 4.6E-7 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain CFK41_RS11575 f81f6b33752b5d317a335b103b8277ac 747 Gene3D G3DSA:3.40.50.300 586 743 5.7E-14 T 28-03-2018 CFK41_RS09360 2a748f5af9abd65ee86731299c816ba7 215 Gene3D G3DSA:3.40.50.2300 12 155 2.7E-33 T 28-03-2018 CFK41_RS09360 2a748f5af9abd65ee86731299c816ba7 215 SMART SM00448 25 136 4.8E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS09360 2a748f5af9abd65ee86731299c816ba7 215 Pfam PF00072 Response regulator receiver domain 28 136 2.4E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS09360 2a748f5af9abd65ee86731299c816ba7 215 Pfam PF03861 ANTAR domain 155 207 2.1E-20 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CFK41_RS09360 2a748f5af9abd65ee86731299c816ba7 215 SUPERFAMILY SSF52172 22 207 1.42E-54 T 28-03-2018 IPR011006 CheY-like superfamily CFK41_RS09360 2a748f5af9abd65ee86731299c816ba7 215 PIRSF PIRSF036382 17 214 4.8E-71 T 28-03-2018 IPR008327 Signal transduction response regulator, antiterminator CFK41_RS09360 2a748f5af9abd65ee86731299c816ba7 215 SMART SM01012 152 207 1.1E-22 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CFK41_RS09360 2a748f5af9abd65ee86731299c816ba7 215 Gene3D G3DSA:1.10.10.10 156 209 2.8E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS13300 1fa261d800a491eb911678d5a25de47b 217 Gene3D G3DSA:1.10.3720.10 1 217 4.5E-36 T 28-03-2018 CFK41_RS13300 1fa261d800a491eb911678d5a25de47b 217 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 19 111 4.5E-14 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CFK41_RS13300 1fa261d800a491eb911678d5a25de47b 217 SUPERFAMILY SSF161098 18 202 9.16E-34 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS13300 1fa261d800a491eb911678d5a25de47b 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 216 1.5E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS13300 1fa261d800a491eb911678d5a25de47b 217 TIGRFAM TIGR03003 ectoine_ehuD: ectoine/hydroxyectoine ABC transporter, permease protein EhuD 6 216 3.6E-66 T 28-03-2018 IPR014341 Ectoine/hydroxyectoine ABC transporter, permease protein EhuD CFK41_RS06175 9328fd1384e5b390b578ef2639c44da1 357 TIGRFAM TIGR03586 PseI: pseudaminic acid synthase 25 352 5.7E-137 T 28-03-2018 IPR020030 Pseudaminic acid biosynthesis, PseI KEGG: 00520+2.5.1.97|MetaCyc: PWY-6143 CFK41_RS06175 9328fd1384e5b390b578ef2639c44da1 357 SUPERFAMILY SSF51569 12 309 1.47E-79 T 28-03-2018 CFK41_RS06175 9328fd1384e5b390b578ef2639c44da1 357 Pfam PF08666 SAF domain 301 356 2.8E-7 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CFK41_RS06175 9328fd1384e5b390b578ef2639c44da1 357 SMART SM00858 300 357 2.3E-8 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CFK41_RS06175 9328fd1384e5b390b578ef2639c44da1 357 SUPERFAMILY SSF51269 298 357 4.24E-15 T 28-03-2018 IPR006190 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal Reactome: R-HSA-4085001 CFK41_RS06175 9328fd1384e5b390b578ef2639c44da1 357 Gene3D G3DSA:3.90.1210.10 288 357 3.2E-21 T 28-03-2018 CFK41_RS06175 9328fd1384e5b390b578ef2639c44da1 357 Gene3D G3DSA:3.20.20.70 11 287 2.6E-81 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS06175 9328fd1384e5b390b578ef2639c44da1 357 Pfam PF03102 NeuB family 45 285 5.3E-80 T 28-03-2018 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 CFK41_RS06755 9d8971db4b42e26ffaa429444d9c7894 271 Gene3D G3DSA:3.20.20.220 5 271 2.3E-32 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CFK41_RS06755 9d8971db4b42e26ffaa429444d9c7894 271 Pfam PF02219 Methylenetetrahydrofolate reductase 25 190 1.8E-12 T 28-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CFK41_RS06755 9d8971db4b42e26ffaa429444d9c7894 271 SUPERFAMILY SSF51730 15 268 5.3E-33 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CFK41_RS16975 a32e86f6272089634ea1f4b80017b341 313 SUPERFAMILY SSF161098 102 295 9.42E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS16975 a32e86f6272089634ea1f4b80017b341 313 Gene3D G3DSA:1.10.3720.10 16 300 1.7E-37 T 28-03-2018 CFK41_RS16975 a32e86f6272089634ea1f4b80017b341 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 309 6.1E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS03710 f5c18c0d8f02449e747ebb045919e40f 329 Pfam PF02779 Transketolase, pyrimidine binding domain 10 181 4.5E-42 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CFK41_RS03710 f5c18c0d8f02449e747ebb045919e40f 329 Gene3D G3DSA:3.40.50.920 199 328 3.5E-31 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CFK41_RS03710 f5c18c0d8f02449e747ebb045919e40f 329 SUPERFAMILY SSF52922 198 327 2.75E-37 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CFK41_RS03710 f5c18c0d8f02449e747ebb045919e40f 329 SMART SM00861 8 183 1.4E-60 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CFK41_RS03710 f5c18c0d8f02449e747ebb045919e40f 329 Pfam PF02780 Transketolase, C-terminal domain 199 319 1.3E-37 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CFK41_RS03710 f5c18c0d8f02449e747ebb045919e40f 329 Gene3D G3DSA:3.40.50.970 4 196 4.2E-56 T 28-03-2018 CFK41_RS03710 f5c18c0d8f02449e747ebb045919e40f 329 SUPERFAMILY SSF52518 9 191 7.25E-64 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CFK41_RS09565 ff0c4071451d44c49f67d8a02ed1d4df 534 SUPERFAMILY SSF52540 332 515 2.56E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS09565 ff0c4071451d44c49f67d8a02ed1d4df 534 SMART SM00382 352 519 1.4E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS09565 ff0c4071451d44c49f67d8a02ed1d4df 534 SMART SM00382 26 234 8.0E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS09565 ff0c4071451d44c49f67d8a02ed1d4df 534 Pfam PF12848 ABC transporter 232 309 3.4E-7 T 28-03-2018 IPR032781 ABC-transporter extension domain CFK41_RS09565 ff0c4071451d44c49f67d8a02ed1d4df 534 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS09565 ff0c4071451d44c49f67d8a02ed1d4df 534 Gene3D G3DSA:3.40.50.300 1 291 6.7E-50 T 28-03-2018 CFK41_RS09565 ff0c4071451d44c49f67d8a02ed1d4df 534 SUPERFAMILY SSF52540 2 232 1.33E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS09565 ff0c4071451d44c49f67d8a02ed1d4df 534 Pfam PF00005 ABC transporter 345 473 5.8E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS09565 ff0c4071451d44c49f67d8a02ed1d4df 534 Pfam PF00005 ABC transporter 18 189 4.3E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS09565 ff0c4071451d44c49f67d8a02ed1d4df 534 Gene3D G3DSA:3.40.50.300 292 532 6.1E-48 T 28-03-2018 CFK41_RS09565 ff0c4071451d44c49f67d8a02ed1d4df 534 ProSitePatterns PS00211 ABC transporters family signature. 445 459 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS17550 0ed9512b8e25e70a77a32b603376b79f 471 Gene3D G3DSA:3.30.460.10 2 148 2.3E-42 T 28-03-2018 CFK41_RS17550 0ed9512b8e25e70a77a32b603376b79f 471 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 176 237 8.1E-21 T 28-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CFK41_RS17550 0ed9512b8e25e70a77a32b603376b79f 471 TIGRFAM TIGR00277 HDIG: HDIG domain 248 326 1.6E-12 T 28-03-2018 IPR006675 HDIG domain CFK41_RS17550 0ed9512b8e25e70a77a32b603376b79f 471 Gene3D G3DSA:1.10.3090.10 149 465 3.9E-73 T 28-03-2018 CFK41_RS17550 0ed9512b8e25e70a77a32b603376b79f 471 SUPERFAMILY SSF81891 147 467 3.66E-65 T 28-03-2018 CFK41_RS17550 0ed9512b8e25e70a77a32b603376b79f 471 SMART SM00471 247 410 5.4E-5 T 28-03-2018 IPR003607 HD/PDEase domain CFK41_RS17550 0ed9512b8e25e70a77a32b603376b79f 471 Pfam PF01966 HD domain 251 348 9.0E-12 T 28-03-2018 IPR006674 HD domain CFK41_RS17550 0ed9512b8e25e70a77a32b603376b79f 471 Pfam PF01743 Poly A polymerase head domain 25 149 2.2E-29 T 28-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CFK41_RS17550 0ed9512b8e25e70a77a32b603376b79f 471 SUPERFAMILY SSF81301 9 144 3.81E-35 T 28-03-2018 CFK41_RS17550 0ed9512b8e25e70a77a32b603376b79f 471 TIGRFAM TIGR02692 tRNA_CCA_actino: CCA tRNA nucleotidyltransferase 8 466 1.9E-214 T 28-03-2018 IPR014065 tRNA adenylyltransferase CFK41_RS03040 6dfa53b47d6331e1044d453d4a5f1ccc 313 SUPERFAMILY SSF51717 38 302 1.11E-79 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CFK41_RS03040 6dfa53b47d6331e1044d453d4a5f1ccc 313 Gene3D G3DSA:3.20.20.20 34 309 1.0E-85 T 28-03-2018 CFK41_RS03040 6dfa53b47d6331e1044d453d4a5f1ccc 313 Pfam PF00809 Pterin binding enzyme 44 284 1.3E-66 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CFK41_RS03040 6dfa53b47d6331e1044d453d4a5f1ccc 313 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 43 298 1.3E-81 T 28-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 CFK41_RS03040 6dfa53b47d6331e1044d453d4a5f1ccc 313 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 43 58 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CFK41_RS16460 81361169531f8b4c37ed71e6c9ef138b 324 Gene3D G3DSA:1.20.58.370 25 72 1.3E-6 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CFK41_RS16460 81361169531f8b4c37ed71e6c9ef138b 324 SUPERFAMILY SSF161098 41 318 3.27E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS16460 81361169531f8b4c37ed71e6c9ef138b 324 Gene3D G3DSA:1.10.3720.10 89 315 2.8E-38 T 28-03-2018 CFK41_RS16460 81361169531f8b4c37ed71e6c9ef138b 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 302 1.2E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS08170 a2e8c9f8a4cb9e5ec7e5b131235b2eaf 180 SUPERFAMILY SSF52218 1 151 9.39E-32 T 28-03-2018 IPR029039 Flavoprotein-like domain CFK41_RS08170 a2e8c9f8a4cb9e5ec7e5b131235b2eaf 180 Gene3D G3DSA:3.40.50.360 1 176 6.9E-31 T 28-03-2018 IPR029039 Flavoprotein-like domain CFK41_RS08170 a2e8c9f8a4cb9e5ec7e5b131235b2eaf 180 Pfam PF03358 NADPH-dependent FMN reductase 2 138 3.6E-27 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CFK41_RS05995 b87d3d2054b3c5ee9da93db2a3c2db7a 591 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 591 5.0E-238 T 28-03-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CFK41_RS05995 b87d3d2054b3c5ee9da93db2a3c2db7a 591 Pfam PF00890 FAD binding domain 7 403 5.4E-111 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CFK41_RS05995 b87d3d2054b3c5ee9da93db2a3c2db7a 591 SUPERFAMILY SSF51905 2 262 9.83E-74 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS05995 b87d3d2054b3c5ee9da93db2a3c2db7a 591 SUPERFAMILY SSF51905 361 426 9.83E-74 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS05995 b87d3d2054b3c5ee9da93db2a3c2db7a 591 SUPERFAMILY SSF56425 239 357 4.93E-40 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CFK41_RS05995 b87d3d2054b3c5ee9da93db2a3c2db7a 591 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 4 591 1.5E-266 T 28-03-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CFK41_RS05995 b87d3d2054b3c5ee9da93db2a3c2db7a 591 SUPERFAMILY SSF46977 453 591 3.4E-40 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CFK41_RS05995 b87d3d2054b3c5ee9da93db2a3c2db7a 591 Gene3D G3DSA:3.50.50.60 317 419 4.3E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS05995 b87d3d2054b3c5ee9da93db2a3c2db7a 591 Gene3D G3DSA:4.10.80.40 539 591 3.7E-15 T 28-03-2018 CFK41_RS05995 b87d3d2054b3c5ee9da93db2a3c2db7a 591 Gene3D G3DSA:1.20.58.100 429 538 1.3E-27 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CFK41_RS05995 b87d3d2054b3c5ee9da93db2a3c2db7a 591 PIRSF PIRSF000171 1 565 2.5E-43 T 28-03-2018 CFK41_RS05995 b87d3d2054b3c5ee9da93db2a3c2db7a 591 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 40 49 - T 28-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CFK41_RS05995 b87d3d2054b3c5ee9da93db2a3c2db7a 591 Pfam PF02910 Fumarate reductase flavoprotein C-term 458 591 2.2E-37 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CFK41_RS05995 b87d3d2054b3c5ee9da93db2a3c2db7a 591 Gene3D G3DSA:3.50.50.60 1 307 9.1E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS16405 281284bf009da2a2237d5251b4f66949 541 Pfam PF13416 Bacterial extracellular solute-binding protein 80 390 9.7E-18 T 28-03-2018 CFK41_RS16405 281284bf009da2a2237d5251b4f66949 541 Gene3D G3DSA:3.40.190.10 63 199 5.0E-9 T 28-03-2018 CFK41_RS16405 281284bf009da2a2237d5251b4f66949 541 Gene3D G3DSA:3.40.190.10 200 401 8.3E-26 T 28-03-2018 CFK41_RS16405 281284bf009da2a2237d5251b4f66949 541 SUPERFAMILY SSF53850 23 538 1.3E-70 T 28-03-2018 CFK41_RS00100 880ddcf85311e8a20dd87965b54304f1 677 PRINTS PR00943 Copper-transporting ATPase signature 279 293 6.9E-9 T 28-03-2018 CFK41_RS00100 880ddcf85311e8a20dd87965b54304f1 677 PRINTS PR00943 Copper-transporting ATPase signature 338 353 6.9E-9 T 28-03-2018 CFK41_RS00100 880ddcf85311e8a20dd87965b54304f1 677 PRINTS PR00943 Copper-transporting ATPase signature 624 638 6.9E-9 T 28-03-2018 CFK41_RS00100 880ddcf85311e8a20dd87965b54304f1 677 PRINTS PR00943 Copper-transporting ATPase signature 78 97 6.9E-9 T 28-03-2018 CFK41_RS00100 880ddcf85311e8a20dd87965b54304f1 677 PRINTS PR00943 Copper-transporting ATPase signature 585 599 6.9E-9 T 28-03-2018 CFK41_RS00100 880ddcf85311e8a20dd87965b54304f1 677 PRINTS PR00943 Copper-transporting ATPase signature 149 167 6.9E-9 T 28-03-2018 CFK41_RS00100 880ddcf85311e8a20dd87965b54304f1 677 PRINTS PR00943 Copper-transporting ATPase signature 528 545 6.9E-9 T 28-03-2018 CFK41_RS00100 880ddcf85311e8a20dd87965b54304f1 677 Gene3D G3DSA:2.70.150.10 12 257 2.5E-27 T 28-03-2018 CFK41_RS00100 880ddcf85311e8a20dd87965b54304f1 677 SUPERFAMILY SSF81665 257 349 9.81E-15 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CFK41_RS00100 880ddcf85311e8a20dd87965b54304f1 677 SUPERFAMILY SSF81665 600 620 9.81E-15 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CFK41_RS00100 880ddcf85311e8a20dd87965b54304f1 677 SUPERFAMILY SSF81665 99 160 9.81E-15 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CFK41_RS00100 880ddcf85311e8a20dd87965b54304f1 677 SUPERFAMILY SSF56784 354 373 3.97E-54 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS00100 880ddcf85311e8a20dd87965b54304f1 677 SUPERFAMILY SSF56784 412 656 3.97E-54 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS00100 880ddcf85311e8a20dd87965b54304f1 677 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 357 363 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CFK41_RS00100 880ddcf85311e8a20dd87965b54304f1 677 SUPERFAMILY SSF81653 159 256 8.24E-22 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CFK41_RS00100 880ddcf85311e8a20dd87965b54304f1 677 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 93 659 1.3E-167 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CFK41_RS00100 880ddcf85311e8a20dd87965b54304f1 677 Gene3D G3DSA:3.40.50.1000 479 617 7.9E-40 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS00100 880ddcf85311e8a20dd87965b54304f1 677 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 75 660 9.8E-164 T 28-03-2018 CFK41_RS00100 880ddcf85311e8a20dd87965b54304f1 677 Gene3D G3DSA:3.40.1110.10 366 478 5.1E-25 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CFK41_RS00100 880ddcf85311e8a20dd87965b54304f1 677 Pfam PF00122 E1-E2 ATPase 157 334 5.1E-45 T 28-03-2018 CFK41_RS00100 880ddcf85311e8a20dd87965b54304f1 677 Pfam PF00702 haloacid dehalogenase-like hydrolase 351 565 2.5E-43 T 28-03-2018 CFK41_RS00100 880ddcf85311e8a20dd87965b54304f1 677 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 129 629 3.2E-83 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CFK41_RS00100 880ddcf85311e8a20dd87965b54304f1 677 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 206 220 1.0E-27 T 28-03-2018 CFK41_RS00100 880ddcf85311e8a20dd87965b54304f1 677 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 498 508 1.0E-27 T 28-03-2018 CFK41_RS00100 880ddcf85311e8a20dd87965b54304f1 677 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 551 570 1.0E-27 T 28-03-2018 CFK41_RS00100 880ddcf85311e8a20dd87965b54304f1 677 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 355 369 1.0E-27 T 28-03-2018 CFK41_RS00100 880ddcf85311e8a20dd87965b54304f1 677 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 476 487 1.0E-27 T 28-03-2018 CFK41_RS00100 880ddcf85311e8a20dd87965b54304f1 677 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 574 586 1.0E-27 T 28-03-2018 CFK41_RS01455 6d2dd28a1fea2a6e30a9bbe98c1ecf54 292 SUPERFAMILY SSF161098 8 292 1.28E-62 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01455 6d2dd28a1fea2a6e30a9bbe98c1ecf54 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 285 3.5E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01455 6d2dd28a1fea2a6e30a9bbe98c1ecf54 292 Gene3D G3DSA:1.10.3720.10 2 279 2.5E-42 T 28-03-2018 CFK41_RS00450 057114e2c96712ef999d14341eb1d52c 461 Gene3D G3DSA:3.30.565.10 255 451 2.2E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS00450 057114e2c96712ef999d14341eb1d52c 461 SUPERFAMILY SSF55874 346 440 3.23E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS00450 057114e2c96712ef999d14341eb1d52c 461 Pfam PF07730 Histidine kinase 231 294 1.8E-14 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CFK41_RS09160 986a8c9a3ca1f8f2382235f3a71be990 742 SUPERFAMILY SSF52540 443 735 9.81E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS09160 986a8c9a3ca1f8f2382235f3a71be990 742 SUPERFAMILY SSF52540 12 232 1.18E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS09160 986a8c9a3ca1f8f2382235f3a71be990 742 SUPERFAMILY SSF52540 310 470 2.7E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS09160 986a8c9a3ca1f8f2382235f3a71be990 742 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 657 735 1.2E-21 T 28-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like CFK41_RS09160 986a8c9a3ca1f8f2382235f3a71be990 742 Gene3D G3DSA:3.30.300.20 658 736 3.7E-25 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CFK41_RS09160 986a8c9a3ca1f8f2382235f3a71be990 742 Gene3D G3DSA:3.40.50.300 253 320 0.059 T 28-03-2018 CFK41_RS09160 986a8c9a3ca1f8f2382235f3a71be990 742 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 484 504 2.4E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CFK41_RS09160 986a8c9a3ca1f8f2382235f3a71be990 742 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 533 548 2.4E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CFK41_RS09160 986a8c9a3ca1f8f2382235f3a71be990 742 TIGRFAM TIGR00017 cmk: cytidylate kinase 13 229 1.6E-51 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CFK41_RS09160 986a8c9a3ca1f8f2382235f3a71be990 742 Pfam PF02224 Cytidylate kinase 15 231 1.1E-53 T 28-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CFK41_RS09160 986a8c9a3ca1f8f2382235f3a71be990 742 Pfam PF01926 50S ribosome-binding GTPase 483 601 8.3E-22 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CFK41_RS09160 986a8c9a3ca1f8f2382235f3a71be990 742 Pfam PF01926 50S ribosome-binding GTPase 311 425 1.5E-24 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CFK41_RS09160 986a8c9a3ca1f8f2382235f3a71be990 742 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 309 430 4.0E-24 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CFK41_RS09160 986a8c9a3ca1f8f2382235f3a71be990 742 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 482 648 9.0E-23 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CFK41_RS09160 986a8c9a3ca1f8f2382235f3a71be990 742 Gene3D G3DSA:3.40.50.300 11 234 6.5E-43 T 28-03-2018 CFK41_RS09160 986a8c9a3ca1f8f2382235f3a71be990 742 Gene3D G3DSA:3.40.50.300 321 474 2.9E-31 T 28-03-2018 CFK41_RS09160 986a8c9a3ca1f8f2382235f3a71be990 742 SMART SM00382 11 197 2.7 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS09160 986a8c9a3ca1f8f2382235f3a71be990 742 SMART SM00382 480 722 0.4 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS09160 986a8c9a3ca1f8f2382235f3a71be990 742 SMART SM00382 307 445 4.0 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS09160 986a8c9a3ca1f8f2382235f3a71be990 742 Gene3D G3DSA:3.40.50.300 475 657 1.9E-33 T 28-03-2018 CFK41_RS09160 986a8c9a3ca1f8f2382235f3a71be990 742 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 309 734 1.7E-156 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CFK41_RS09160 986a8c9a3ca1f8f2382235f3a71be990 742 Hamap MF_00238 Cytidylate kinase [cmk]. 13 235 25.488 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CFK41_RS09160 986a8c9a3ca1f8f2382235f3a71be990 742 Hamap MF_00195 GTPase Der [der]. 308 738 35.547 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CFK41_RS09045 15c2daad68d09b249222585fbecf98f4 192 Gene3D G3DSA:1.10.10.60 1 37 3.4E-17 T 28-03-2018 CFK41_RS09045 15c2daad68d09b249222585fbecf98f4 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 2.5E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS09045 15c2daad68d09b249222585fbecf98f4 192 Gene3D G3DSA:1.10.260.40 38 68 5.8E-12 T 28-03-2018 CFK41_RS09045 15c2daad68d09b249222585fbecf98f4 192 SUPERFAMILY SSF46689 2 83 1.39E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS09045 15c2daad68d09b249222585fbecf98f4 192 Gene3D G3DSA:1.10.357.10 69 192 4.5E-9 T 28-03-2018 CFK41_RS09045 15c2daad68d09b249222585fbecf98f4 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 2.0E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS09045 15c2daad68d09b249222585fbecf98f4 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 2.0E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS15215 5efbdebe33f42bfdeb0a8f53b59952e1 342 SMART SM00354 7 77 1.2E-13 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS15215 5efbdebe33f42bfdeb0a8f53b59952e1 342 Gene3D G3DSA:3.40.50.2300 178 342 3.3E-28 T 28-03-2018 CFK41_RS15215 5efbdebe33f42bfdeb0a8f53b59952e1 342 SUPERFAMILY SSF47413 7 65 1.19E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS15215 5efbdebe33f42bfdeb0a8f53b59952e1 342 Pfam PF13377 Periplasmic binding protein-like domain 180 339 6.0E-24 T 28-03-2018 CFK41_RS15215 5efbdebe33f42bfdeb0a8f53b59952e1 342 SUPERFAMILY SSF53822 64 320 3.34E-40 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS15215 5efbdebe33f42bfdeb0a8f53b59952e1 342 Gene3D G3DSA:1.10.260.40 23 62 8.9E-20 T 28-03-2018 CFK41_RS15215 5efbdebe33f42bfdeb0a8f53b59952e1 342 Gene3D G3DSA:1.10.10.10 3 22 3.4E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS15215 5efbdebe33f42bfdeb0a8f53b59952e1 342 Pfam PF00356 Bacterial regulatory proteins, lacI family 13 53 7.5E-10 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS15215 5efbdebe33f42bfdeb0a8f53b59952e1 342 Gene3D G3DSA:3.40.50.2300 63 177 2.8E-16 T 28-03-2018 CFK41_RS13105 cb7d72d1042748fdc165e1e76294e411 201 SUPERFAMILY SSF46689 7 72 4.61E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS13105 cb7d72d1042748fdc165e1e76294e411 201 SUPERFAMILY SSF48498 91 186 4.17E-7 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CFK41_RS13105 cb7d72d1042748fdc165e1e76294e411 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 1.1E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS13105 cb7d72d1042748fdc165e1e76294e411 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 5.6E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS13105 cb7d72d1042748fdc165e1e76294e411 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 5.6E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS13105 cb7d72d1042748fdc165e1e76294e411 201 Gene3D G3DSA:1.10.357.10 2 198 1.3E-24 T 28-03-2018 CFK41_RS08980 73163bc2a700f259b52f4d80146206d7 194 SMART SM00422 37 109 3.8E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS08980 73163bc2a700f259b52f4d80146206d7 194 Pfam PF13411 MerR HTH family regulatory protein 40 106 2.9E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS08980 73163bc2a700f259b52f4d80146206d7 194 SUPERFAMILY SSF46955 40 125 3.59E-14 T 28-03-2018 IPR009061 Putative DNA-binding domain CFK41_RS08980 73163bc2a700f259b52f4d80146206d7 194 Gene3D G3DSA:1.10.1660.10 31 193 2.4E-16 T 28-03-2018 CFK41_RS16835 4e4511bc789022c326012b6b16fff473 233 Pfam PF05988 Bacterial protein of unknown function (DUF899) 9 210 7.3E-59 T 28-03-2018 IPR010296 Protein of unknown function DUF899, thioredoxin-like CFK41_RS16835 4e4511bc789022c326012b6b16fff473 233 Gene3D G3DSA:3.40.30.10 19 193 4.4E-8 T 28-03-2018 CFK41_RS00050 e8798f650203a96c129e0680964fc86f 789 SUPERFAMILY SSF51621 465 786 1.2E-90 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CFK41_RS00050 e8798f650203a96c129e0680964fc86f 789 Gene3D G3DSA:3.20.20.60 477 787 6.5E-101 T 28-03-2018 CFK41_RS00050 e8798f650203a96c129e0680964fc86f 789 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 693 711 - T 28-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 CFK41_RS00050 e8798f650203a96c129e0680964fc86f 789 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 481 780 8.1E-54 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CFK41_RS00050 e8798f650203a96c129e0680964fc86f 789 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 18 341 2.8E-114 T 28-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CFK41_RS00050 e8798f650203a96c129e0680964fc86f 789 Pfam PF00391 PEP-utilising enzyme, mobile domain 383 454 2.5E-26 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CFK41_RS00050 e8798f650203a96c129e0680964fc86f 789 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 5 785 0.0 T 28-03-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 CFK41_RS00050 e8798f650203a96c129e0680964fc86f 789 SUPERFAMILY SSF52009 349 466 5.23E-34 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CFK41_RS00050 e8798f650203a96c129e0680964fc86f 789 Gene3D G3DSA:3.30.470.20 194 356 1.1E-41 T 28-03-2018 CFK41_RS00050 e8798f650203a96c129e0680964fc86f 789 SUPERFAMILY SSF56059 1 384 1.77E-104 T 28-03-2018 CFK41_RS00050 e8798f650203a96c129e0680964fc86f 789 Gene3D G3DSA:3.30.1490.20 1 193 4.7E-54 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CFK41_RS00050 e8798f650203a96c129e0680964fc86f 789 Gene3D G3DSA:3.50.30.10 357 475 1.1E-36 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CFK41_RS00050 e8798f650203a96c129e0680964fc86f 789 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 413 424 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CFK41_RS00050 e8798f650203a96c129e0680964fc86f 789 PIRSF PIRSF000854 1 789 0.0 T 28-03-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 CFK41_RS11430 6ea86db73bc19e1a6222eb52dc8279b1 349 SUPERFAMILY SSF51726 19 337 1.94E-12 T 28-03-2018 CFK41_RS11430 6ea86db73bc19e1a6222eb52dc8279b1 349 Gene3D G3DSA:3.20.20.210 17 347 3.3E-26 T 28-03-2018 CFK41_RS04695 be58d895ad195a483da888f12f81e43f 282 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 2.5E-18 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CFK41_RS04695 be58d895ad195a483da888f12f81e43f 282 PRINTS PR00599 Methionine aminopeptidase-1 signature 169 181 2.5E-18 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CFK41_RS04695 be58d895ad195a483da888f12f81e43f 282 PRINTS PR00599 Methionine aminopeptidase-1 signature 200 212 2.5E-18 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CFK41_RS04695 be58d895ad195a483da888f12f81e43f 282 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 2.5E-18 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CFK41_RS04695 be58d895ad195a483da888f12f81e43f 282 SUPERFAMILY SSF55920 5 257 5.1E-69 T 28-03-2018 IPR000994 Peptidase M24 CFK41_RS04695 be58d895ad195a483da888f12f81e43f 282 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 175 193 - T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CFK41_RS04695 be58d895ad195a483da888f12f81e43f 282 Hamap MF_01974 Methionine aminopeptidase [map]. 8 258 35.233 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CFK41_RS04695 be58d895ad195a483da888f12f81e43f 282 Pfam PF00557 Metallopeptidase family M24 19 249 1.2E-43 T 28-03-2018 IPR000994 Peptidase M24 CFK41_RS04695 be58d895ad195a483da888f12f81e43f 282 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 9 257 6.2E-76 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CFK41_RS04695 be58d895ad195a483da888f12f81e43f 282 Gene3D G3DSA:3.90.230.10 8 261 1.4E-66 T 28-03-2018 CFK41_RS15685 11df759bca41723a73533d9b8cdfe7ac 517 SMART SM00507 372 423 4.2E-7 T 28-03-2018 IPR003615 HNH nuclease CFK41_RS15685 11df759bca41723a73533d9b8cdfe7ac 517 Pfam PF02720 Domain of unknown function (DUF222) 36 381 8.2E-25 T 28-03-2018 IPR003870 Domain of unknown function DUF222 CFK41_RS15685 11df759bca41723a73533d9b8cdfe7ac 517 Gene3D G3DSA:3.40.1800.10 363 431 6.6E-11 T 28-03-2018 CFK41_RS15685 11df759bca41723a73533d9b8cdfe7ac 517 Pfam PF01844 HNH endonuclease 388 426 2.9E-6 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CFK41_RS15065 7e8b10b0597c8e3511d1517b79e2b0bd 41 SUPERFAMILY SSF57840 1 39 3.14E-11 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS15065 7e8b10b0597c8e3511d1517b79e2b0bd 41 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 40 6.7E-6 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS15065 7e8b10b0597c8e3511d1517b79e2b0bd 41 Pfam PF00444 Ribosomal protein L36 1 39 6.5E-16 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS15065 7e8b10b0597c8e3511d1517b79e2b0bd 41 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 40 14.251 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS07695 79a7831b120721611fb5554982f56bc3 629 Pfam PF00570 HRDC domain 556 623 6.7E-20 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CFK41_RS07695 79a7831b120721611fb5554982f56bc3 629 SMART SM00487 33 229 6.1E-27 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CFK41_RS07695 79a7831b120721611fb5554982f56bc3 629 SMART SM00341 553 629 4.8E-12 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CFK41_RS07695 79a7831b120721611fb5554982f56bc3 629 Gene3D G3DSA:3.40.50.300 14 219 2.5E-30 T 28-03-2018 CFK41_RS07695 79a7831b120721611fb5554982f56bc3 629 SUPERFAMILY SSF47819 549 625 9.38E-21 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 CFK41_RS07695 79a7831b120721611fb5554982f56bc3 629 SUPERFAMILY SSF52540 219 468 2.06E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS07695 79a7831b120721611fb5554982f56bc3 629 Gene3D G3DSA:1.10.10.10 368 538 1.3E-45 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS07695 79a7831b120721611fb5554982f56bc3 629 Gene3D G3DSA:3.40.50.300 221 367 3.7E-30 T 28-03-2018 CFK41_RS07695 79a7831b120721611fb5554982f56bc3 629 Gene3D G3DSA:1.10.150.80 539 629 1.1E-24 T 28-03-2018 CFK41_RS07695 79a7831b120721611fb5554982f56bc3 629 Pfam PF09382 RQC domain 418 532 2.7E-31 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CFK41_RS07695 79a7831b120721611fb5554982f56bc3 629 Pfam PF00271 Helicase conserved C-terminal domain 236 342 6.9E-16 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS07695 79a7831b120721611fb5554982f56bc3 629 SUPERFAMILY SSF52540 19 207 1.63E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS07695 79a7831b120721611fb5554982f56bc3 629 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 26 622 4.4E-225 T 28-03-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 CFK41_RS07695 79a7831b120721611fb5554982f56bc3 629 Pfam PF00270 DEAD/DEAH box helicase 40 197 5.9E-17 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CFK41_RS07695 79a7831b120721611fb5554982f56bc3 629 Pfam PF16124 RecQ zinc-binding 355 416 8.9E-18 T 28-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain CFK41_RS07695 79a7831b120721611fb5554982f56bc3 629 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 26 478 1.0E-147 T 28-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CFK41_RS07695 79a7831b120721611fb5554982f56bc3 629 SMART SM00490 262 343 3.8E-24 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS07695 79a7831b120721611fb5554982f56bc3 629 SMART SM00956 423 529 1.2E-37 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CFK41_RS03990 ac1e5bd3946d3ad44dba6ecd80ba73b8 259 SUPERFAMILY SSF55781 65 251 9.81E-28 T 28-03-2018 IPR029016 GAF domain-like CFK41_RS03990 ac1e5bd3946d3ad44dba6ecd80ba73b8 259 Gene3D G3DSA:1.10.10.10 1 78 4.6E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS03990 ac1e5bd3946d3ad44dba6ecd80ba73b8 259 SMART SM00346 8 87 7.7E-4 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CFK41_RS03990 ac1e5bd3946d3ad44dba6ecd80ba73b8 259 Pfam PF01614 Bacterial transcriptional regulator 127 248 2.2E-15 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CFK41_RS03990 ac1e5bd3946d3ad44dba6ecd80ba73b8 259 SUPERFAMILY SSF46785 10 81 1.07E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS03990 ac1e5bd3946d3ad44dba6ecd80ba73b8 259 Gene3D G3DSA:3.30.450.40 100 256 1.0E-29 T 28-03-2018 IPR029016 GAF domain-like CFK41_RS03990 ac1e5bd3946d3ad44dba6ecd80ba73b8 259 Pfam PF09339 IclR helix-turn-helix domain 10 60 7.3E-10 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CFK41_RS14285 acb547cd102a7869b42c1514a9076e64 516 SUPERFAMILY SSF51445 40 386 4.42E-102 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS14285 acb547cd102a7869b42c1514a9076e64 516 Pfam PF01120 Alpha-L-fucosidase 31 382 2.8E-98 T 28-03-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS14285 acb547cd102a7869b42c1514a9076e64 516 Gene3D G3DSA:3.20.20.80 34 386 4.9E-108 T 28-03-2018 CFK41_RS14285 acb547cd102a7869b42c1514a9076e64 516 SMART SM00812 39 450 1.4E-171 T 28-03-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS14285 acb547cd102a7869b42c1514a9076e64 516 PRINTS PR00741 Glycosyl hydrolase family 29 signature 238 254 4.5E-19 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS14285 acb547cd102a7869b42c1514a9076e64 516 PRINTS PR00741 Glycosyl hydrolase family 29 signature 336 357 4.5E-19 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS14285 acb547cd102a7869b42c1514a9076e64 516 PRINTS PR00741 Glycosyl hydrolase family 29 signature 105 120 4.5E-19 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS14285 acb547cd102a7869b42c1514a9076e64 516 PRINTS PR00741 Glycosyl hydrolase family 29 signature 369 391 4.5E-19 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS14285 acb547cd102a7869b42c1514a9076e64 516 Gene3D G3DSA:2.60.40.1180 387 507 6.6E-20 T 28-03-2018 CFK41_RS06265 1fbda889a4a551886ba43799dc611b1f 1135 Gene3D G3DSA:3.90.550.10 4 356 3.3E-15 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS06265 1fbda889a4a551886ba43799dc611b1f 1135 SUPERFAMILY SSF53448 6 66 2.48E-15 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS06265 1fbda889a4a551886ba43799dc611b1f 1135 SUPERFAMILY SSF53448 262 346 2.48E-15 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS06265 1fbda889a4a551886ba43799dc611b1f 1135 SUPERFAMILY SSF53448 152 225 2.48E-15 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS15170 0e849e35705eb43fcc0a1b951a86ba35 184 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 65 113 6.2E-14 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CFK41_RS15170 0e849e35705eb43fcc0a1b951a86ba35 184 SUPERFAMILY SSF69118 59 182 1.57E-29 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CFK41_RS15170 0e849e35705eb43fcc0a1b951a86ba35 184 Pfam PF02627 Carboxymuconolactone decarboxylase family 61 126 8.9E-17 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CFK41_RS15170 0e849e35705eb43fcc0a1b951a86ba35 184 Gene3D G3DSA:1.20.1290.10 33 181 8.6E-26 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CFK41_RS04950 f4611b5d3410a2eaa33c5d766e8f1ca2 295 Gene3D G3DSA:3.40.50.300 46 274 1.2E-51 T 28-03-2018 CFK41_RS04950 f4611b5d3410a2eaa33c5d766e8f1ca2 295 SMART SM00382 73 257 8.5E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS04950 f4611b5d3410a2eaa33c5d766e8f1ca2 295 SUPERFAMILY SSF52540 48 271 9.82E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS04950 f4611b5d3410a2eaa33c5d766e8f1ca2 295 Pfam PF00005 ABC transporter 65 207 9.0E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS07060 3b26aa22a53af322e9a036feffdb2db5 303 Gene3D G3DSA:1.10.287.80 242 290 5.9E-12 T 28-03-2018 CFK41_RS07060 3b26aa22a53af322e9a036feffdb2db5 303 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 5 295 2.2E-71 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07060 3b26aa22a53af322e9a036feffdb2db5 303 Pfam PF00231 ATP synthase 6 295 7.3E-70 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07060 3b26aa22a53af322e9a036feffdb2db5 303 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 281 294 - T 28-03-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07060 3b26aa22a53af322e9a036feffdb2db5 303 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 295 28.268 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07060 3b26aa22a53af322e9a036feffdb2db5 303 Gene3D G3DSA:3.40.1380.10 28 241 4.6E-54 T 28-03-2018 CFK41_RS07060 3b26aa22a53af322e9a036feffdb2db5 303 PRINTS PR00126 ATP synthase gamma subunit signature 242 261 4.9E-24 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07060 3b26aa22a53af322e9a036feffdb2db5 303 PRINTS PR00126 ATP synthase gamma subunit signature 76 95 4.9E-24 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07060 3b26aa22a53af322e9a036feffdb2db5 303 PRINTS PR00126 ATP synthase gamma subunit signature 273 294 4.9E-24 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07060 3b26aa22a53af322e9a036feffdb2db5 303 PRINTS PR00126 ATP synthase gamma subunit signature 173 190 4.9E-24 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07060 3b26aa22a53af322e9a036feffdb2db5 303 SUPERFAMILY SSF52943 4 295 1.57E-63 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS12430 5090c2dd3bf53a978e6ec8b4f38ea32b 387 Pfam PF00586 AIR synthase related protein, N-terminal domain 71 175 1.3E-16 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CFK41_RS12430 5090c2dd3bf53a978e6ec8b4f38ea32b 387 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 16 365 39.899 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CFK41_RS12430 5090c2dd3bf53a978e6ec8b4f38ea32b 387 Pfam PF02769 AIR synthase related protein, C-terminal domain 187 353 2.0E-30 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CFK41_RS12430 5090c2dd3bf53a978e6ec8b4f38ea32b 387 SUPERFAMILY SSF56042 183 353 2.24E-49 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CFK41_RS12430 5090c2dd3bf53a978e6ec8b4f38ea32b 387 Gene3D G3DSA:3.90.650.10 182 355 3.4E-53 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CFK41_RS12430 5090c2dd3bf53a978e6ec8b4f38ea32b 387 Gene3D G3DSA:3.30.1330.10 47 172 1.5E-45 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CFK41_RS12430 5090c2dd3bf53a978e6ec8b4f38ea32b 387 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 16 350 1.1E-118 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CFK41_RS12430 5090c2dd3bf53a978e6ec8b4f38ea32b 387 SUPERFAMILY SSF55326 16 178 1.64E-43 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CFK41_RS04530 06dfc0ffdb0fe7db97a6ac137f57935e 124 Pfam PF00164 Ribosomal protein S12/S23 12 123 2.6E-42 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS04530 06dfc0ffdb0fe7db97a6ac137f57935e 124 PIRSF PIRSF002133 1 124 1.9E-53 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS04530 06dfc0ffdb0fe7db97a6ac137f57935e 124 SUPERFAMILY SSF50249 2 123 2.48E-51 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS04530 06dfc0ffdb0fe7db97a6ac137f57935e 124 Gene3D G3DSA:2.40.50.140 1 124 1.2E-62 T 28-03-2018 CFK41_RS04530 06dfc0ffdb0fe7db97a6ac137f57935e 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 3.3E-56 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS04530 06dfc0ffdb0fe7db97a6ac137f57935e 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 3.3E-56 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS04530 06dfc0ffdb0fe7db97a6ac137f57935e 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 3.3E-56 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS04530 06dfc0ffdb0fe7db97a6ac137f57935e 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 3.3E-56 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS04530 06dfc0ffdb0fe7db97a6ac137f57935e 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 3.3E-56 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS04530 06dfc0ffdb0fe7db97a6ac137f57935e 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 3.3E-56 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS04530 06dfc0ffdb0fe7db97a6ac137f57935e 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 2 124 2.0E-65 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04530 06dfc0ffdb0fe7db97a6ac137f57935e 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS04530 06dfc0ffdb0fe7db97a6ac137f57935e 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 38.578 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS08280 8ebf336206b8738324017fbda0a81d06 463 SUPERFAMILY SSF55681 9 372 1.68E-115 T 28-03-2018 CFK41_RS08280 8ebf336206b8738324017fbda0a81d06 463 SUPERFAMILY SSF52954 356 460 2.42E-32 T 28-03-2018 IPR004154 Anticodon-binding CFK41_RS08280 8ebf336206b8738324017fbda0a81d06 463 Gene3D G3DSA:3.40.50.800 361 460 2.7E-26 T 28-03-2018 IPR004154 Anticodon-binding CFK41_RS08280 8ebf336206b8738324017fbda0a81d06 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 320 332 1.1E-51 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CFK41_RS08280 8ebf336206b8738324017fbda0a81d06 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 406 425 1.1E-51 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CFK41_RS08280 8ebf336206b8738324017fbda0a81d06 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 161 178 1.1E-51 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CFK41_RS08280 8ebf336206b8738324017fbda0a81d06 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 28 42 1.1E-51 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CFK41_RS08280 8ebf336206b8738324017fbda0a81d06 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 140 152 1.1E-51 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CFK41_RS08280 8ebf336206b8738324017fbda0a81d06 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 193 210 1.1E-51 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CFK41_RS08280 8ebf336206b8738324017fbda0a81d06 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 210 220 1.1E-51 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CFK41_RS08280 8ebf336206b8738324017fbda0a81d06 463 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 161 336 5.8E-10 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS08280 8ebf336206b8738324017fbda0a81d06 463 Gene3D G3DSA:3.30.930.10 232 360 7.3E-37 T 28-03-2018 CFK41_RS08280 8ebf336206b8738324017fbda0a81d06 463 Gene3D G3DSA:3.30.930.10 6 231 2.7E-51 T 28-03-2018 CFK41_RS08280 8ebf336206b8738324017fbda0a81d06 463 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 6 461 47.304 T 28-03-2018 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 CFK41_RS08280 8ebf336206b8738324017fbda0a81d06 463 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 10 235 3.1E-79 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CFK41_RS08280 8ebf336206b8738324017fbda0a81d06 463 Pfam PF03129 Anticodon binding domain 369 456 1.1E-21 T 28-03-2018 IPR004154 Anticodon-binding CFK41_RS06350 04f1b770ce0a7cc8444ba6fc5382977f 262 Gene3D G3DSA:3.40.50.2020 96 260 7.3E-14 T 28-03-2018 CFK41_RS06350 04f1b770ce0a7cc8444ba6fc5382977f 262 SUPERFAMILY SSF53271 101 257 9.96E-14 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CFK41_RS06350 04f1b770ce0a7cc8444ba6fc5382977f 262 Pfam PF00156 Phosphoribosyl transferase domain 209 249 3.5E-8 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CFK41_RS17020 bd65c03ad1df3c35e5ebbe49beb34771 430 Gene3D G3DSA:1.20.1250.20 3 224 2.2E-16 T 28-03-2018 CFK41_RS17020 bd65c03ad1df3c35e5ebbe49beb34771 430 SUPERFAMILY SSF103473 4 416 8.63E-37 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS17020 bd65c03ad1df3c35e5ebbe49beb34771 430 TIGRFAM TIGR00885 fucP: L-fucose:H+ symporter permease 3 406 2.8E-122 T 28-03-2018 IPR005275 L-fucose permease FucP GO:0015150|GO:0015756 CFK41_RS17020 bd65c03ad1df3c35e5ebbe49beb34771 430 Gene3D G3DSA:1.20.1250.20 225 414 9.2E-23 T 28-03-2018 CFK41_RS17020 bd65c03ad1df3c35e5ebbe49beb34771 430 Pfam PF07690 Major Facilitator Superfamily 244 424 5.9E-11 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS08200 eb973b130a03837710bb24fa6ceee0ce 615 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 284 297 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CFK41_RS08200 eb973b130a03837710bb24fa6ceee0ce 615 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 81 97 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CFK41_RS08200 eb973b130a03837710bb24fa6ceee0ce 615 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 46 609 54.638 T 28-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CFK41_RS08200 eb973b130a03837710bb24fa6ceee0ce 615 SUPERFAMILY SSF89000 439 488 2.79E-14 T 28-03-2018 CFK41_RS08200 eb973b130a03837710bb24fa6ceee0ce 615 SMART SM00917 473 608 1.2E-37 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CFK41_RS08200 eb973b130a03837710bb24fa6ceee0ce 615 Gene3D G3DSA:3.20.20.70 51 427 7.6E-111 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS08200 eb973b130a03837710bb24fa6ceee0ce 615 Pfam PF08502 LeuA allosteric (dimerisation) domain 473 607 8.4E-32 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CFK41_RS08200 eb973b130a03837710bb24fa6ceee0ce 615 Pfam PF00682 HMGL-like 74 354 3.2E-75 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CFK41_RS08200 eb973b130a03837710bb24fa6ceee0ce 615 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 45 609 2.6E-254 T 28-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CFK41_RS08200 eb973b130a03837710bb24fa6ceee0ce 615 SUPERFAMILY SSF51569 63 371 1.76E-97 T 28-03-2018 CFK41_RS08200 eb973b130a03837710bb24fa6ceee0ce 615 SUPERFAMILY SSF110921 507 607 1.7E-35 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 379 397 1.8E-61 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.8E-61 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.8E-61 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 1.8E-61 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 1.8E-61 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 1.8E-61 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 1.8E-61 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 SUPERFAMILY SSF52440 563 688 2.88E-40 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 Gene3D G3DSA:3.40.50.20 544 668 2.4E-54 T 28-03-2018 CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 Gene3D G3DSA:3.30.470.20 119 402 1.4E-63 T 28-03-2018 CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 Gene3D G3DSA:3.40.50.20 4 117 1.8E-35 T 28-03-2018 CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 SMART SM01096 423 552 1.2E-39 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 1.1E-64 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 687 889 1.5E-30 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 SUPERFAMILY SSF52440 1 127 2.01E-46 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 SUPERFAMILY SSF56059 687 964 7.42E-86 T 28-03-2018 CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 SUPERFAMILY SSF56059 128 400 1.94E-101 T 28-03-2018 CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 SMART SM00851 987 1075 1.0E-16 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 Gene3D G3DSA:3.30.470.20 764 964 6.9E-34 T 28-03-2018 CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 Gene3D G3DSA:3.30.1490.20 669 763 2.2E-17 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 Gene3D G3DSA:3.40.50.1380 965 1109 2.7E-40 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 453 552 4.0E-29 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 Pfam PF02142 MGS-like domain 992 1075 3.3E-16 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 854 861 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 Gene3D G3DSA:1.10.1030.10 412 543 2.2E-36 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1096 12.411 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 3 1086 0.0 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 723 737 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 SUPERFAMILY SSF52335 967 1105 4.19E-29 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CFK41_RS09520 7c46f0afa0b83448b283d4f76131659a 1117 SUPERFAMILY SSF48108 396 558 3.14E-32 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CFK41_RS17200 41e69d52fd9b28fb5084a632e26883f5 330 Gene3D G3DSA:3.40.50.970 3 199 9.9E-37 T 28-03-2018 CFK41_RS17200 41e69d52fd9b28fb5084a632e26883f5 330 SUPERFAMILY SSF52922 195 330 9.82E-31 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CFK41_RS17200 41e69d52fd9b28fb5084a632e26883f5 330 Gene3D G3DSA:3.40.50.920 201 330 9.8E-32 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CFK41_RS17200 41e69d52fd9b28fb5084a632e26883f5 330 Pfam PF02779 Transketolase, pyrimidine binding domain 27 188 1.9E-32 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CFK41_RS17200 41e69d52fd9b28fb5084a632e26883f5 330 SMART SM00861 25 189 2.7E-41 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CFK41_RS17200 41e69d52fd9b28fb5084a632e26883f5 330 Pfam PF02780 Transketolase, C-terminal domain 201 319 4.1E-24 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CFK41_RS17200 41e69d52fd9b28fb5084a632e26883f5 330 SUPERFAMILY SSF52518 23 190 8.57E-45 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CFK41_RS02395 aa4325bf8b4389b93f0b5c0eaa8fa4e2 542 Gene3D G3DSA:2.30.40.10 1 97 2.3E-20 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS02395 aa4325bf8b4389b93f0b5c0eaa8fa4e2 542 Pfam PF07969 Amidohydrolase family 49 540 6.5E-94 T 28-03-2018 IPR013108 Amidohydrolase 3 CFK41_RS02395 aa4325bf8b4389b93f0b5c0eaa8fa4e2 542 SUPERFAMILY SSF51338 499 540 9.78E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS02395 aa4325bf8b4389b93f0b5c0eaa8fa4e2 542 SUPERFAMILY SSF51338 2 60 9.78E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS02395 aa4325bf8b4389b93f0b5c0eaa8fa4e2 542 Gene3D G3DSA:3.20.20.140 205 497 8.8E-48 T 28-03-2018 CFK41_RS02395 aa4325bf8b4389b93f0b5c0eaa8fa4e2 542 SUPERFAMILY SSF51556 207 499 7.56E-28 T 28-03-2018 IPR032466 Metal-dependent hydrolase CFK41_RS02395 aa4325bf8b4389b93f0b5c0eaa8fa4e2 542 SUPERFAMILY SSF51556 59 94 7.56E-28 T 28-03-2018 IPR032466 Metal-dependent hydrolase CFK41_RS01755 bd9e590ac8019ebf17408bf2ff14ed23 677 Pfam PF01095 Pectinesterase 364 670 6.0E-29 T 28-03-2018 IPR000070 Pectinesterase, catalytic GO:0005618|GO:0030599|GO:0042545 KEGG: 00040+3.1.1.11|MetaCyc: PWY-1081|MetaCyc: PWY-7246|MetaCyc: PWY-7248 CFK41_RS01755 bd9e590ac8019ebf17408bf2ff14ed23 677 SUPERFAMILY SSF51126 60 353 2.36E-56 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CFK41_RS01755 bd9e590ac8019ebf17408bf2ff14ed23 677 Pfam PF00544 Pectate lyase 120 282 3.1E-14 T 28-03-2018 IPR002022 Pectate lyase CFK41_RS01755 bd9e590ac8019ebf17408bf2ff14ed23 677 Gene3D G3DSA:2.160.20.10 118 355 1.5E-48 T 28-03-2018 IPR012334 Pectin lyase fold CFK41_RS01755 bd9e590ac8019ebf17408bf2ff14ed23 677 Gene3D G3DSA:2.160.20.10 356 677 3.4E-64 T 28-03-2018 IPR012334 Pectin lyase fold CFK41_RS01755 bd9e590ac8019ebf17408bf2ff14ed23 677 SMART SM00656 81 296 1.6E-7 T 28-03-2018 IPR002022 Pectate lyase CFK41_RS01755 bd9e590ac8019ebf17408bf2ff14ed23 677 SMART SM00710 148 183 5.8 T 28-03-2018 IPR006626 Parallel beta-helix repeat CFK41_RS01755 bd9e590ac8019ebf17408bf2ff14ed23 677 SMART SM00710 456 499 830.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CFK41_RS01755 bd9e590ac8019ebf17408bf2ff14ed23 677 SMART SM00710 184 205 5200.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CFK41_RS01755 bd9e590ac8019ebf17408bf2ff14ed23 677 SUPERFAMILY SSF51126 360 674 3.56E-49 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CFK41_RS01755 bd9e590ac8019ebf17408bf2ff14ed23 677 Gene3D G3DSA:2.160.20.10 43 117 6.8E-6 T 28-03-2018 IPR012334 Pectin lyase fold CFK41_RS03020 d65f44775fea75f27d4af20c3ca03e32 237 Pfam PF12401 Protein of unknown function (DUF2662) 4 116 4.3E-34 T 28-03-2018 IPR022128 Domain of unknown function DUF3662 CFK41_RS03020 d65f44775fea75f27d4af20c3ca03e32 237 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 146 227 1.5E-17 T 28-03-2018 IPR032030 YscD, cytoplasmic domain CFK41_RS03020 d65f44775fea75f27d4af20c3ca03e32 237 SUPERFAMILY SSF49879 146 230 8.23E-25 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 CFK41_RS03020 d65f44775fea75f27d4af20c3ca03e32 237 Gene3D G3DSA:2.60.200.20 104 231 6.2E-25 T 28-03-2018 CFK41_RS03020 d65f44775fea75f27d4af20c3ca03e32 237 SMART SM00240 155 206 7.2E-15 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CFK41_RS00190 5870bb3a49780eadeae574624fbcebf8 280 Pfam PF01261 Xylose isomerase-like TIM barrel 57 214 4.9E-13 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS00190 5870bb3a49780eadeae574624fbcebf8 280 SUPERFAMILY SSF51658 16 265 4.28E-24 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS00190 5870bb3a49780eadeae574624fbcebf8 280 Gene3D G3DSA:3.20.20.150 16 279 1.4E-25 T 28-03-2018 CFK41_RS11705 d54f2124bbb247eecaec4ca7418124b4 447 Pfam PF00675 Insulinase (Peptidase family M16) 34 154 4.9E-29 T 28-03-2018 IPR011765 Peptidase M16, N-terminal CFK41_RS11705 d54f2124bbb247eecaec4ca7418124b4 447 Pfam PF05193 Peptidase M16 inactive domain 187 379 1.2E-39 T 28-03-2018 IPR007863 Peptidase M16, C-terminal CFK41_RS11705 d54f2124bbb247eecaec4ca7418124b4 447 SUPERFAMILY SSF63411 20 226 3.67E-49 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CFK41_RS11705 d54f2124bbb247eecaec4ca7418124b4 447 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 53 76 - T 28-03-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 CFK41_RS11705 d54f2124bbb247eecaec4ca7418124b4 447 SUPERFAMILY SSF63411 269 442 1.75E-42 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CFK41_RS11705 d54f2124bbb247eecaec4ca7418124b4 447 Gene3D G3DSA:3.30.830.10 13 228 4.7E-48 T 28-03-2018 CFK41_RS11705 d54f2124bbb247eecaec4ca7418124b4 447 Gene3D G3DSA:3.30.830.10 277 445 6.0E-41 T 28-03-2018 CFK41_RS03145 fe35e8cf0127e8d2dcc032b0d64c3cd9 262 SUPERFAMILY SSF69618 10 241 1.7E-35 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CFK41_RS03145 fe35e8cf0127e8d2dcc032b0d64c3cd9 262 Pfam PF02602 Uroporphyrinogen-III synthase HemD 23 234 3.8E-29 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CFK41_RS03145 fe35e8cf0127e8d2dcc032b0d64c3cd9 262 Gene3D G3DSA:3.40.50.10090 39 153 1.1E-18 T 28-03-2018 CFK41_RS03145 fe35e8cf0127e8d2dcc032b0d64c3cd9 262 Gene3D G3DSA:3.40.50.10090 154 244 2.2E-15 T 28-03-2018 CFK41_RS00350 f641960d2cd750699b93b31db045e7e5 245 Pfam PF00005 ABC transporter 18 166 1.9E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS00350 f641960d2cd750699b93b31db045e7e5 245 SUPERFAMILY SSF52540 3 225 5.56E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS00350 f641960d2cd750699b93b31db045e7e5 245 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS00350 f641960d2cd750699b93b31db045e7e5 245 Gene3D G3DSA:3.40.50.300 1 233 9.4E-56 T 28-03-2018 CFK41_RS00350 f641960d2cd750699b93b31db045e7e5 245 SMART SM00382 27 222 5.0E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS05685 228432819aa1f76f9a97b585531b13ab 208 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 169 26.927 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CFK41_RS05685 228432819aa1f76f9a97b585531b13ab 208 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 6 169 1.7E-54 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CFK41_RS05685 228432819aa1f76f9a97b585531b13ab 208 SUPERFAMILY SSF55200 84 168 4.19E-30 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CFK41_RS05685 228432819aa1f76f9a97b585531b13ab 208 Gene3D G3DSA:3.30.110.10 78 177 7.4E-33 T 28-03-2018 CFK41_RS05685 228432819aa1f76f9a97b585531b13ab 208 Gene3D G3DSA:3.10.20.80 2 77 5.3E-29 T 28-03-2018 CFK41_RS05685 228432819aa1f76f9a97b585531b13ab 208 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 84 166 9.0E-32 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CFK41_RS05685 228432819aa1f76f9a97b585531b13ab 208 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 6 75 1.6E-27 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CFK41_RS05685 228432819aa1f76f9a97b585531b13ab 208 SUPERFAMILY SSF54364 4 77 8.76E-26 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CFK41_RS01470 956733b4b0984d04885e719efbff4fbf 119 Pfam PF05336 L-rhamnose mutarotase 20 109 1.0E-21 T 28-03-2018 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 CFK41_RS01470 956733b4b0984d04885e719efbff4fbf 119 SUPERFAMILY SSF54909 20 118 3.99E-23 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CFK41_RS01470 956733b4b0984d04885e719efbff4fbf 119 Gene3D G3DSA:3.30.70.100 18 111 5.2E-5 T 28-03-2018 CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 SMART SM00433 41 696 5.9E-262 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 Gene3D G3DSA:3.30.230.10 259 452 8.0E-50 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 SMART SM00387 37 203 3.4E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 634 691 3.2E-24 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 Gene3D G3DSA:3.40.50.670 459 699 6.9E-85 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 SUPERFAMILY SSF54211 255 451 1.25E-36 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 SUPERFAMILY SSF56719 454 702 4.71E-78 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 PRINTS PR01159 DNA gyrase subunit B signature 12 22 3.6E-32 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 PRINTS PR01159 DNA gyrase subunit B signature 224 237 3.6E-32 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 PRINTS PR01159 DNA gyrase subunit B signature 434 454 3.6E-32 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 PRINTS PR01159 DNA gyrase subunit B signature 530 539 3.6E-32 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 PRINTS PR01159 DNA gyrase subunit B signature 368 384 3.6E-32 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 PRINTS PR01159 DNA gyrase subunit B signature 295 313 3.6E-32 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 PRINTS PR01159 DNA gyrase subunit B signature 672 688 3.6E-32 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 PRINTS PR01159 DNA gyrase subunit B signature 656 668 3.6E-32 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 PRINTS PR00418 DNA topoisomerase II family signature 546 562 2.3E-61 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 PRINTS PR00418 DNA topoisomerase II family signature 76 89 2.3E-61 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 PRINTS PR00418 DNA topoisomerase II family signature 584 596 2.3E-61 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 PRINTS PR00418 DNA topoisomerase II family signature 321 334 2.3E-61 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 PRINTS PR00418 DNA topoisomerase II family signature 635 651 2.3E-61 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 PRINTS PR00418 DNA topoisomerase II family signature 564 581 2.3E-61 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 PRINTS PR00418 DNA topoisomerase II family signature 41 56 2.3E-61 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 PRINTS PR00418 DNA topoisomerase II family signature 480 494 2.3E-61 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 PRINTS PR00418 DNA topoisomerase II family signature 119 133 2.3E-61 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 SUPERFAMILY SSF55874 12 238 1.7E-56 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 Pfam PF01751 Toprim domain 479 588 9.3E-17 T 28-03-2018 IPR006171 TOPRIM domain CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 ProSitePatterns PS00177 DNA topoisomerase II signature. 482 490 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 Gene3D G3DSA:3.30.565.10 22 258 1.5E-59 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 Pfam PF00204 DNA gyrase B 255 450 1.2E-51 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS09750 f1acb7943e732fdadcf3040b1cda32b9 705 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 37 146 2.1E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS04520 318ff67598e72ed81264f887f7969209 1294 Pfam PF05000 RNA polymerase Rpb1, domain 4 756 817 1.5E-10 T 28-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS04520 318ff67598e72ed81264f887f7969209 1294 Gene3D G3DSA:2.40.40.20 421 563 1.0E-38 T 28-03-2018 CFK41_RS04520 318ff67598e72ed81264f887f7969209 1294 Pfam PF04998 RNA polymerase Rpb1, domain 5 829 1157 7.7E-61 T 28-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS04520 318ff67598e72ed81264f887f7969209 1294 SUPERFAMILY SSF64484 5 1246 0.0 T 28-03-2018 CFK41_RS04520 318ff67598e72ed81264f887f7969209 1294 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 417 4.7E-79 T 28-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS04520 318ff67598e72ed81264f887f7969209 1294 Pfam PF04983 RNA polymerase Rpb1, domain 3 564 722 1.5E-18 T 28-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS04520 318ff67598e72ed81264f887f7969209 1294 Pfam PF00623 RNA polymerase Rpb1, domain 2 419 468 1.0E-7 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS04520 318ff67598e72ed81264f887f7969209 1294 Pfam PF00623 RNA polymerase Rpb1, domain 2 469 560 1.2E-27 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS04520 318ff67598e72ed81264f887f7969209 1294 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1244 0.0 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS04520 318ff67598e72ed81264f887f7969209 1294 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1254 17.272 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS04520 318ff67598e72ed81264f887f7969209 1294 SMART SM00663 310 589 7.2E-168 T 28-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS04520 318ff67598e72ed81264f887f7969209 1294 Gene3D G3DSA:2.40.50.100 972 1092 2.7E-37 T 28-03-2018 CFK41_RS03105 ae8c5b1ca4a0fc538cbd16f6571c574e 220 Pfam PF00805 Pentapeptide repeats (8 copies) 38 59 2.4E-5 T 28-03-2018 IPR001646 Pentapeptide repeat CFK41_RS03105 ae8c5b1ca4a0fc538cbd16f6571c574e 220 SUPERFAMILY SSF141571 33 185 1.28E-24 T 28-03-2018 CFK41_RS03105 ae8c5b1ca4a0fc538cbd16f6571c574e 220 Gene3D G3DSA:2.160.20.80 18 199 5.7E-22 T 28-03-2018 CFK41_RS03105 ae8c5b1ca4a0fc538cbd16f6571c574e 220 Pfam PF13599 Pentapeptide repeats (9 copies) 92 178 3.8E-7 T 28-03-2018 IPR001646 Pentapeptide repeat CFK41_RS02115 d101afb8ecc6df2392596cce69963f92 461 Pfam PF01370 NAD dependent epimerase/dehydratase family 166 284 2.0E-6 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CFK41_RS02115 d101afb8ecc6df2392596cce69963f92 461 SUPERFAMILY SSF55961 1 147 3.25E-10 T 28-03-2018 CFK41_RS02115 d101afb8ecc6df2392596cce69963f92 461 Gene3D G3DSA:3.40.50.720 163 461 4.1E-33 T 28-03-2018 CFK41_RS02115 d101afb8ecc6df2392596cce69963f92 461 Gene3D G3DSA:3.30.530.20 1 159 1.8E-15 T 28-03-2018 IPR023393 START-like domain CFK41_RS02115 d101afb8ecc6df2392596cce69963f92 461 Pfam PF08338 Domain of unknown function (DUF1731) 410 458 1.3E-9 T 28-03-2018 IPR013549 Domain of unknown function DUF1731 CFK41_RS02115 d101afb8ecc6df2392596cce69963f92 461 SUPERFAMILY SSF51735 163 459 3.06E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS02115 d101afb8ecc6df2392596cce69963f92 461 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 165 455 2.0E-75 T 28-03-2018 IPR010099 Epimerase family protein SDR39U1 CFK41_RS17130 258f0ebc8f5e937fe89a5ab865c1fd13 211 SMART SM00345 1 47 1.2E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS17130 258f0ebc8f5e937fe89a5ab865c1fd13 211 Gene3D G3DSA:1.20.120.530 52 210 1.1E-28 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS17130 258f0ebc8f5e937fe89a5ab865c1fd13 211 Pfam PF07729 FCD domain 72 193 6.2E-23 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS17130 258f0ebc8f5e937fe89a5ab865c1fd13 211 SUPERFAMILY SSF48008 70 201 4.97E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS17130 258f0ebc8f5e937fe89a5ab865c1fd13 211 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 7 21 2.0E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS17130 258f0ebc8f5e937fe89a5ab865c1fd13 211 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 21 37 2.0E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS17130 258f0ebc8f5e937fe89a5ab865c1fd13 211 SUPERFAMILY SSF46785 2 51 2.29E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS17130 258f0ebc8f5e937fe89a5ab865c1fd13 211 Gene3D G3DSA:1.10.10.10 1 49 2.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS17130 258f0ebc8f5e937fe89a5ab865c1fd13 211 Pfam PF00392 Bacterial regulatory proteins, gntR family 2 46 2.2E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS17130 258f0ebc8f5e937fe89a5ab865c1fd13 211 SMART SM00895 72 194 3.7E-16 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS04265 16551ebbdebb651d4eafa236aa9ad3a1 285 SMART SM01134 96 266 9.2E-32 T 28-03-2018 CFK41_RS04265 16551ebbdebb651d4eafa236aa9ad3a1 285 ProSitePatterns PS00894 DeoR-type HTH domain signature. 29 63 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CFK41_RS04265 16551ebbdebb651d4eafa236aa9ad3a1 285 Pfam PF08220 DeoR-like helix-turn-helix domain 29 82 1.0E-12 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CFK41_RS04265 16551ebbdebb651d4eafa236aa9ad3a1 285 SUPERFAMILY SSF46785 27 85 3.34E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS04265 16551ebbdebb651d4eafa236aa9ad3a1 285 SMART SM00420 29 81 1.5E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CFK41_RS04265 16551ebbdebb651d4eafa236aa9ad3a1 285 Gene3D G3DSA:1.10.10.60 23 54 1.2E-5 T 28-03-2018 CFK41_RS04265 16551ebbdebb651d4eafa236aa9ad3a1 285 Gene3D G3DSA:3.40.50.1360 102 264 3.6E-29 T 28-03-2018 CFK41_RS04265 16551ebbdebb651d4eafa236aa9ad3a1 285 SUPERFAMILY SSF100950 100 260 9.31E-16 T 28-03-2018 CFK41_RS04265 16551ebbdebb651d4eafa236aa9ad3a1 285 Gene3D G3DSA:1.10.260.40 55 101 3.4E-4 T 28-03-2018 CFK41_RS04265 16551ebbdebb651d4eafa236aa9ad3a1 285 Pfam PF00455 DeoR C terminal sensor domain 100 262 9.1E-29 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CFK41_RS04265 16551ebbdebb651d4eafa236aa9ad3a1 285 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 61 79 2.5E-6 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CFK41_RS04265 16551ebbdebb651d4eafa236aa9ad3a1 285 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 47 61 2.5E-6 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CFK41_RS15765 af7e58e5551bb639a00ecac23cea014e 532 SMART SM00388 270 334 4.1E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CFK41_RS15765 af7e58e5551bb639a00ecac23cea014e 532 SMART SM00387 375 488 4.5E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS15765 af7e58e5551bb639a00ecac23cea014e 532 Gene3D G3DSA:3.30.565.10 341 496 2.0E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS15765 af7e58e5551bb639a00ecac23cea014e 532 Pfam PF00512 His Kinase A (phospho-acceptor) domain 271 329 2.2E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CFK41_RS15765 af7e58e5551bb639a00ecac23cea014e 532 Gene3D G3DSA:3.40.190.10 91 242 0.0082 T 28-03-2018 CFK41_RS15765 af7e58e5551bb639a00ecac23cea014e 532 SUPERFAMILY SSF55874 335 488 6.16E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS15765 af7e58e5551bb639a00ecac23cea014e 532 Gene3D G3DSA:1.10.287.130 260 329 5.8E-12 T 28-03-2018 CFK41_RS15765 af7e58e5551bb639a00ecac23cea014e 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 430 1.4E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS15765 af7e58e5551bb639a00ecac23cea014e 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 472 485 1.4E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS15765 af7e58e5551bb639a00ecac23cea014e 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 444 1.4E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS15765 af7e58e5551bb639a00ecac23cea014e 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 448 466 1.4E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS15765 af7e58e5551bb639a00ecac23cea014e 532 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 376 486 6.2E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS15765 af7e58e5551bb639a00ecac23cea014e 532 Pfam PF00672 HAMP domain 217 266 5.2E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CFK41_RS15765 af7e58e5551bb639a00ecac23cea014e 532 SUPERFAMILY SSF158472 217 265 6.67E-9 T 28-03-2018 CFK41_RS15765 af7e58e5551bb639a00ecac23cea014e 532 SUPERFAMILY SSF47384 253 329 5.3E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CFK41_RS15765 af7e58e5551bb639a00ecac23cea014e 532 SMART SM00304 216 269 2.1E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CFK41_RS01145 1c8505ce19fcd6453f68db56254e1f65 514 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 6 504 1.1E-216 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CFK41_RS01145 1c8505ce19fcd6453f68db56254e1f65 514 Gene3D G3DSA:3.30.420.40 1 252 8.6E-88 T 28-03-2018 CFK41_RS01145 1c8505ce19fcd6453f68db56254e1f65 514 PIRSF PIRSF000538 5 510 1.3E-166 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CFK41_RS01145 1c8505ce19fcd6453f68db56254e1f65 514 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 266 458 3.7E-61 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CFK41_RS01145 1c8505ce19fcd6453f68db56254e1f65 514 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 367 387 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CFK41_RS01145 1c8505ce19fcd6453f68db56254e1f65 514 Gene3D G3DSA:3.30.420.40 253 512 7.6E-77 T 28-03-2018 CFK41_RS01145 1c8505ce19fcd6453f68db56254e1f65 514 Hamap MF_00186 Glycerol kinase [glpK]. 5 505 55.573 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CFK41_RS01145 1c8505ce19fcd6453f68db56254e1f65 514 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 137 149 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CFK41_RS01145 1c8505ce19fcd6453f68db56254e1f65 514 SUPERFAMILY SSF53067 6 259 1.3E-89 T 28-03-2018 CFK41_RS01145 1c8505ce19fcd6453f68db56254e1f65 514 SUPERFAMILY SSF53067 259 505 1.17E-76 T 28-03-2018 CFK41_RS01145 1c8505ce19fcd6453f68db56254e1f65 514 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 256 1.4E-76 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CFK41_RS09535 8854675ab114fbc80c63adc1aa4ec743 442 SUPERFAMILY SSF51556 63 373 2.66E-99 T 28-03-2018 IPR032466 Metal-dependent hydrolase CFK41_RS09535 8854675ab114fbc80c63adc1aa4ec743 442 SUPERFAMILY SSF51338 379 440 1.85E-22 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS09535 8854675ab114fbc80c63adc1aa4ec743 442 SUPERFAMILY SSF51338 15 62 1.85E-22 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS09535 8854675ab114fbc80c63adc1aa4ec743 442 Hamap MF_00220_B Dihydroorotase [pyrC]. 14 437 41.859 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CFK41_RS09535 8854675ab114fbc80c63adc1aa4ec743 442 Gene3D G3DSA:2.30.40.10 389 436 0.09 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS09535 8854675ab114fbc80c63adc1aa4ec743 442 ProSitePatterns PS00483 Dihydroorotase signature 2. 313 324 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CFK41_RS09535 8854675ab114fbc80c63adc1aa4ec743 442 Gene3D G3DSA:2.30.40.10 14 77 6.4E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS09535 8854675ab114fbc80c63adc1aa4ec743 442 Pfam PF01979 Amidohydrolase family 59 431 2.0E-23 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CFK41_RS09535 8854675ab114fbc80c63adc1aa4ec743 442 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 29 436 1.4E-124 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CFK41_RS09535 8854675ab114fbc80c63adc1aa4ec743 442 Gene3D G3DSA:3.20.20.140 78 388 6.4E-96 T 28-03-2018 CFK41_RS11645 903c606c16475f5703db39c87e3b279a 101 SUPERFAMILY SSF47413 2 71 1.96E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS11645 903c606c16475f5703db39c87e3b279a 101 Pfam PF13560 Helix-turn-helix domain 7 63 1.5E-10 T 28-03-2018 CFK41_RS11645 903c606c16475f5703db39c87e3b279a 101 SMART SM00530 11 66 2.8E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CFK41_RS11645 903c606c16475f5703db39c87e3b279a 101 Gene3D G3DSA:1.10.260.40 4 77 1.2E-13 T 28-03-2018 CFK41_RS11160 bf9045efe0621bbad7038a7777813c2e 426 SUPERFAMILY SSF53850 30 422 7.25E-44 T 28-03-2018 CFK41_RS11160 bf9045efe0621bbad7038a7777813c2e 426 Gene3D G3DSA:3.40.190.10 10 164 3.3E-20 T 28-03-2018 CFK41_RS11160 bf9045efe0621bbad7038a7777813c2e 426 Pfam PF13416 Bacterial extracellular solute-binding protein 42 351 2.0E-18 T 28-03-2018 CFK41_RS11160 bf9045efe0621bbad7038a7777813c2e 426 Gene3D G3DSA:3.40.190.10 165 369 1.1E-18 T 28-03-2018 CFK41_RS01375 0507c6946c0eef3b8128adedf35ee968 336 ProSitePatterns PS00356 LacI-type HTH domain signature. 9 27 - T 28-03-2018 CFK41_RS01375 0507c6946c0eef3b8128adedf35ee968 336 SUPERFAMILY SSF47413 6 64 3.94E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS01375 0507c6946c0eef3b8128adedf35ee968 336 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 18 28 6.6E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS01375 0507c6946c0eef3b8128adedf35ee968 336 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 8 18 6.6E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS01375 0507c6946c0eef3b8128adedf35ee968 336 Gene3D G3DSA:3.40.50.2300 63 170 1.3E-26 T 28-03-2018 CFK41_RS01375 0507c6946c0eef3b8128adedf35ee968 336 SUPERFAMILY SSF53822 65 334 6.16E-59 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS01375 0507c6946c0eef3b8128adedf35ee968 336 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 53 2.9E-17 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS01375 0507c6946c0eef3b8128adedf35ee968 336 Gene3D G3DSA:1.10.260.40 7 62 8.2E-21 T 28-03-2018 CFK41_RS01375 0507c6946c0eef3b8128adedf35ee968 336 Pfam PF13377 Periplasmic binding protein-like domain 172 334 2.4E-34 T 28-03-2018 CFK41_RS01375 0507c6946c0eef3b8128adedf35ee968 336 SMART SM00354 6 76 6.2E-25 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS01375 0507c6946c0eef3b8128adedf35ee968 336 Gene3D G3DSA:3.40.50.2300 171 335 1.4E-41 T 28-03-2018 CFK41_RS13030 06f0d41a07393eab3f107fb4d943c275 410 Gene3D G3DSA:3.90.1150.10 273 407 2.4E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS13030 06f0d41a07393eab3f107fb4d943c275 410 Gene3D G3DSA:3.40.640.10 63 272 2.8E-44 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS13030 06f0d41a07393eab3f107fb4d943c275 410 SUPERFAMILY SSF53383 33 403 2.61E-82 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS13030 06f0d41a07393eab3f107fb4d943c275 410 Pfam PF00155 Aminotransferase class I and II 50 399 1.5E-27 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CFK41_RS04590 48463a20409640b20f4c4fde84b44f2f 278 Gene3D G3DSA:2.30.30.30 120 196 5.4E-30 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CFK41_RS04590 48463a20409640b20f4c4fde84b44f2f 278 PIRSF PIRSF002158 16 275 3.5E-93 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS04590 48463a20409640b20f4c4fde84b44f2f 278 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 47.838 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CFK41_RS04590 48463a20409640b20f4c4fde84b44f2f 278 SUPERFAMILY SSF50104 127 271 8.42E-56 T 28-03-2018 IPR008991 Translation protein SH3-like domain CFK41_RS04590 48463a20409640b20f4c4fde84b44f2f 278 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 28-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04590 48463a20409640b20f4c4fde84b44f2f 278 SMART SM01382 125 253 4.7E-90 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CFK41_RS04590 48463a20409640b20f4c4fde84b44f2f 278 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 1.7E-126 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CFK41_RS04590 48463a20409640b20f4c4fde84b44f2f 278 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 251 7.1E-56 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CFK41_RS04590 48463a20409640b20f4c4fde84b44f2f 278 SMART SM01383 42 119 3.8E-41 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS04590 48463a20409640b20f4c4fde84b44f2f 278 Gene3D G3DSA:2.40.50.140 1 115 7.6E-45 T 28-03-2018 CFK41_RS04590 48463a20409640b20f4c4fde84b44f2f 278 Gene3D G3DSA:4.10.950.10 198 273 2.1E-29 T 28-03-2018 IPR014726 Ribosomal protein L2, domain 3 CFK41_RS04590 48463a20409640b20f4c4fde84b44f2f 278 SUPERFAMILY SSF50249 2 126 2.67E-48 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS04590 48463a20409640b20f4c4fde84b44f2f 278 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 1.2E-33 T 28-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS08600 f1208361b24849aa33d95489e83a8b87 291 Gene3D G3DSA:3.30.1330.30 23 119 3.8E-13 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CFK41_RS08600 f1208361b24849aa33d95489e83a8b87 291 Pfam PF00588 SpoU rRNA Methylase family 134 279 4.3E-31 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CFK41_RS08600 f1208361b24849aa33d95489e83a8b87 291 Gene3D G3DSA:3.40.1280.10 120 291 2.6E-42 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CFK41_RS08600 f1208361b24849aa33d95489e83a8b87 291 SUPERFAMILY SSF55315 24 107 4.0E-8 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CFK41_RS08600 f1208361b24849aa33d95489e83a8b87 291 SUPERFAMILY SSF75217 126 285 2.22E-37 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CFK41_RS01020 2a9ff1dc694d8981d909e98a57027e75 734 Gene3D G3DSA:1.10.1040.10 660 724 3.3E-4 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CFK41_RS01020 2a9ff1dc694d8981d909e98a57027e75 734 Gene3D G3DSA:3.90.226.10 22 316 3.1E-38 T 28-03-2018 CFK41_RS01020 2a9ff1dc694d8981d909e98a57027e75 734 SUPERFAMILY SSF48179 543 624 3.49E-15 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CFK41_RS01020 2a9ff1dc694d8981d909e98a57027e75 734 SUPERFAMILY SSF48179 671 717 2.13E-8 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CFK41_RS01020 2a9ff1dc694d8981d909e98a57027e75 734 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 544 622 1.1E-15 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CFK41_RS01020 2a9ff1dc694d8981d909e98a57027e75 734 SUPERFAMILY SSF52096 52 216 3.45E-38 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CFK41_RS01020 2a9ff1dc694d8981d909e98a57027e75 734 SUPERFAMILY SSF52096 282 338 3.45E-38 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CFK41_RS01020 2a9ff1dc694d8981d909e98a57027e75 734 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 363 541 2.7E-50 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CFK41_RS01020 2a9ff1dc694d8981d909e98a57027e75 734 Pfam PF00378 Enoyl-CoA hydratase/isomerase 55 205 2.8E-24 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CFK41_RS01020 2a9ff1dc694d8981d909e98a57027e75 734 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 118 138 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CFK41_RS01020 2a9ff1dc694d8981d909e98a57027e75 734 SUPERFAMILY SSF51735 358 543 3.84E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS01020 2a9ff1dc694d8981d909e98a57027e75 734 Gene3D G3DSA:1.10.1040.10 544 629 1.8E-14 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CFK41_RS01020 2a9ff1dc694d8981d909e98a57027e75 734 Gene3D G3DSA:3.40.50.720 317 543 1.2E-47 T 28-03-2018 CFK41_RS04195 f8265316fa9ec4618cb69d60bfa642b9 365 SUPERFAMILY SSF51735 9 163 1.48E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS04195 f8265316fa9ec4618cb69d60bfa642b9 365 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 13 130 4.4E-24 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS04195 f8265316fa9ec4618cb69d60bfa642b9 365 SUPERFAMILY SSF55347 140 331 1.96E-27 T 28-03-2018 CFK41_RS04195 f8265316fa9ec4618cb69d60bfa642b9 365 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 146 209 2.8E-8 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CFK41_RS04195 f8265316fa9ec4618cb69d60bfa642b9 365 Gene3D G3DSA:3.40.50.720 6 143 1.9E-34 T 28-03-2018 CFK41_RS04195 f8265316fa9ec4618cb69d60bfa642b9 365 Gene3D G3DSA:3.30.360.10 144 365 1.5E-35 T 28-03-2018 CFK41_RS17305 62dc741f1c092f18c9cd988def80f79d 158 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 23 36 9.1E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS17305 62dc741f1c092f18c9cd988def80f79d 158 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 46 66 9.1E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS17305 62dc741f1c092f18c9cd988def80f79d 158 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 12 23 9.1E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS17305 62dc741f1c092f18c9cd988def80f79d 158 SUPERFAMILY SSF46955 10 121 3.26E-24 T 28-03-2018 IPR009061 Putative DNA-binding domain CFK41_RS17305 62dc741f1c092f18c9cd988def80f79d 158 Pfam PF09278 MerR, DNA binding 53 118 1.3E-13 T 28-03-2018 IPR015358 Transcription regulator MerR, DNA binding CFK41_RS17305 62dc741f1c092f18c9cd988def80f79d 158 ProSitePatterns PS00552 MerR-type HTH domain signature. 14 36 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS17305 62dc741f1c092f18c9cd988def80f79d 158 SMART SM00422 11 79 6.0E-20 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS17305 62dc741f1c092f18c9cd988def80f79d 158 Gene3D G3DSA:1.10.1660.10 7 65 2.6E-16 T 28-03-2018 CFK41_RS17305 62dc741f1c092f18c9cd988def80f79d 158 Pfam PF00376 MerR family regulatory protein 12 48 1.8E-10 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS17305 62dc741f1c092f18c9cd988def80f79d 158 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 11 150 1.2E-54 T 28-03-2018 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 CFK41_RS17305 62dc741f1c092f18c9cd988def80f79d 158 Gene3D G3DSA:1.10.1660.10 66 141 7.3E-9 T 28-03-2018 CFK41_RS07540 7987d6edccabb91d423b62b37a9d9074 424 PIRSF PIRSF000151 1 424 8.8E-164 T 28-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CFK41_RS07540 7987d6edccabb91d423b62b37a9d9074 424 SUPERFAMILY SSF53720 9 423 2.36E-110 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CFK41_RS07540 7987d6edccabb91d423b62b37a9d9074 424 Gene3D G3DSA:3.40.605.10 2 241 1.1E-37 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CFK41_RS07540 7987d6edccabb91d423b62b37a9d9074 424 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 8 423 39.625 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CFK41_RS07540 7987d6edccabb91d423b62b37a9d9074 424 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 330 351 - T 28-03-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CFK41_RS07540 7987d6edccabb91d423b62b37a9d9074 424 Gene3D G3DSA:3.40.605.10 242 424 2.9E-38 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CFK41_RS07540 7987d6edccabb91d423b62b37a9d9074 424 Pfam PF00171 Aldehyde dehydrogenase family 8 281 1.5E-16 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CFK41_RS07540 7987d6edccabb91d423b62b37a9d9074 424 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 16 413 9.8E-135 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CFK41_RS09960 b22c74e21d0c3c7584e0a7489f89d1a5 346 SUPERFAMILY SSF46785 260 333 1.36E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS09960 b22c74e21d0c3c7584e0a7489f89d1a5 346 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 253 335 5.0E-27 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CFK41_RS09960 b22c74e21d0c3c7584e0a7489f89d1a5 346 SUPERFAMILY SSF52540 23 254 2.95E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS09960 b22c74e21d0c3c7584e0a7489f89d1a5 346 Gene3D G3DSA:1.10.10.10 260 330 1.4E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS09960 b22c74e21d0c3c7584e0a7489f89d1a5 346 Gene3D G3DSA:3.40.50.300 21 184 4.3E-29 T 28-03-2018 CFK41_RS09960 b22c74e21d0c3c7584e0a7489f89d1a5 346 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 9 238 2.6E-105 T 28-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CFK41_RS09960 b22c74e21d0c3c7584e0a7489f89d1a5 346 Gene3D G3DSA:1.10.8.60 187 257 4.8E-28 T 28-03-2018 CFK41_RS09960 b22c74e21d0c3c7584e0a7489f89d1a5 346 SMART SM00382 54 185 4.7E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS09960 b22c74e21d0c3c7584e0a7489f89d1a5 346 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 27 329 6.3E-131 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CFK41_RS09960 b22c74e21d0c3c7584e0a7489f89d1a5 346 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 346 152.84 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CFK41_RS09960 b22c74e21d0c3c7584e0a7489f89d1a5 346 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 62 81 4.2E-5 T 28-03-2018 CFK41_RS09960 b22c74e21d0c3c7584e0a7489f89d1a5 346 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 331 346 4.2E-5 T 28-03-2018 CFK41_RS09960 b22c74e21d0c3c7584e0a7489f89d1a5 346 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 256 329 7.4E-28 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CFK41_RS03675 76858b175fa0ebc13667f3ce78ed67d2 547 SMART SM00388 312 383 1.8E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CFK41_RS03675 76858b175fa0ebc13667f3ce78ed67d2 547 Gene3D G3DSA:1.10.287.130 319 379 7.0E-14 T 28-03-2018 CFK41_RS03675 76858b175fa0ebc13667f3ce78ed67d2 547 Pfam PF00512 His Kinase A (phospho-acceptor) domain 314 379 3.4E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CFK41_RS03675 76858b175fa0ebc13667f3ce78ed67d2 547 SUPERFAMILY SSF47384 303 379 1.02E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CFK41_RS03675 76858b175fa0ebc13667f3ce78ed67d2 547 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 435 544 1.2E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS03675 76858b175fa0ebc13667f3ce78ed67d2 547 SUPERFAMILY SSF55874 392 544 2.1E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS03675 76858b175fa0ebc13667f3ce78ed67d2 547 SMART SM00387 434 546 2.5E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS03675 76858b175fa0ebc13667f3ce78ed67d2 547 PRINTS PR00344 Bacterial sensor protein C-terminal signature 489 499 9.8E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS03675 76858b175fa0ebc13667f3ce78ed67d2 547 PRINTS PR00344 Bacterial sensor protein C-terminal signature 530 543 9.8E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS03675 76858b175fa0ebc13667f3ce78ed67d2 547 PRINTS PR00344 Bacterial sensor protein C-terminal signature 506 524 9.8E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS03675 76858b175fa0ebc13667f3ce78ed67d2 547 PRINTS PR00344 Bacterial sensor protein C-terminal signature 471 485 9.8E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS03675 76858b175fa0ebc13667f3ce78ed67d2 547 Gene3D G3DSA:3.30.450.20 191 318 5.4E-6 T 28-03-2018 CFK41_RS03675 76858b175fa0ebc13667f3ce78ed67d2 547 Gene3D G3DSA:3.30.565.10 392 547 2.2E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS12760 37beea31db2aeadf21e86efa2de49fbc 249 Gene3D G3DSA:1.20.120.530 81 240 3.6E-17 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS12760 37beea31db2aeadf21e86efa2de49fbc 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 30 44 1.8E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS12760 37beea31db2aeadf21e86efa2de49fbc 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 60 1.8E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS12760 37beea31db2aeadf21e86efa2de49fbc 249 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 70 6.3E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS12760 37beea31db2aeadf21e86efa2de49fbc 249 Gene3D G3DSA:1.10.10.10 2 71 2.5E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS12760 37beea31db2aeadf21e86efa2de49fbc 249 Pfam PF07729 FCD domain 99 220 5.8E-17 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS12760 37beea31db2aeadf21e86efa2de49fbc 249 SUPERFAMILY SSF48008 97 225 4.97E-18 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS12760 37beea31db2aeadf21e86efa2de49fbc 249 SMART SM00895 99 222 1.3E-8 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS12760 37beea31db2aeadf21e86efa2de49fbc 249 SUPERFAMILY SSF46785 10 74 7.44E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS12760 37beea31db2aeadf21e86efa2de49fbc 249 SMART SM00345 11 70 1.2E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS14365 374506c852cb676b26877ec3cecd73f6 566 Pfam PF01547 Bacterial extracellular solute-binding protein 148 384 1.4E-8 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CFK41_RS14365 374506c852cb676b26877ec3cecd73f6 566 Gene3D G3DSA:3.40.190.10 236 566 1.8E-16 T 28-03-2018 CFK41_RS14365 374506c852cb676b26877ec3cecd73f6 566 SUPERFAMILY SSF53850 47 53 6.7E-40 T 28-03-2018 CFK41_RS14365 374506c852cb676b26877ec3cecd73f6 566 SUPERFAMILY SSF53850 114 565 6.7E-40 T 28-03-2018 CFK41_RS16345 2143c649d5d067eab365f74345b80e60 450 SUPERFAMILY SSF53850 50 448 1.27E-54 T 28-03-2018 CFK41_RS16345 2143c649d5d067eab365f74345b80e60 450 Gene3D G3DSA:3.40.190.10 164 449 3.4E-40 T 28-03-2018 CFK41_RS16345 2143c649d5d067eab365f74345b80e60 450 Pfam PF13416 Bacterial extracellular solute-binding protein 80 372 1.2E-39 T 28-03-2018 CFK41_RS12515 34ef8a3bd186ca12a1d7b99e33092c29 529 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 204 529 4.8E-140 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CFK41_RS12515 34ef8a3bd186ca12a1d7b99e33092c29 529 Pfam PF00958 GMP synthase C terminal domain 437 528 6.4E-38 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CFK41_RS12515 34ef8a3bd186ca12a1d7b99e33092c29 529 Gene3D G3DSA:3.40.50.880 4 214 8.8E-46 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS12515 34ef8a3bd186ca12a1d7b99e33092c29 529 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 6 529 52.101 T 28-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 CFK41_RS12515 34ef8a3bd186ca12a1d7b99e33092c29 529 PRINTS PR00096 Glutamine amidotransferase superfamily signature 53 62 2.5E-6 T 28-03-2018 CFK41_RS12515 34ef8a3bd186ca12a1d7b99e33092c29 529 PRINTS PR00096 Glutamine amidotransferase superfamily signature 169 182 2.5E-6 T 28-03-2018 CFK41_RS12515 34ef8a3bd186ca12a1d7b99e33092c29 529 PRINTS PR00096 Glutamine amidotransferase superfamily signature 80 91 2.5E-6 T 28-03-2018 CFK41_RS12515 34ef8a3bd186ca12a1d7b99e33092c29 529 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 9 191 2.8E-70 T 28-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CFK41_RS12515 34ef8a3bd186ca12a1d7b99e33092c29 529 Gene3D G3DSA:3.40.50.620 215 403 7.3E-33 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS12515 34ef8a3bd186ca12a1d7b99e33092c29 529 SUPERFAMILY SSF52317 8 229 2.69E-49 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS12515 34ef8a3bd186ca12a1d7b99e33092c29 529 PRINTS PR00097 Anthranilate synthase component II signature 53 62 8.1E-5 T 28-03-2018 CFK41_RS12515 34ef8a3bd186ca12a1d7b99e33092c29 529 PRINTS PR00097 Anthranilate synthase component II signature 80 91 8.1E-5 T 28-03-2018 CFK41_RS12515 34ef8a3bd186ca12a1d7b99e33092c29 529 PRINTS PR00097 Anthranilate synthase component II signature 169 182 8.1E-5 T 28-03-2018 CFK41_RS12515 34ef8a3bd186ca12a1d7b99e33092c29 529 Gene3D G3DSA:3.30.300.10 404 529 2.0E-51 T 28-03-2018 CFK41_RS12515 34ef8a3bd186ca12a1d7b99e33092c29 529 Pfam PF00117 Glutamine amidotransferase class-I 11 191 9.3E-36 T 28-03-2018 IPR017926 Glutamine amidotransferase CFK41_RS12515 34ef8a3bd186ca12a1d7b99e33092c29 529 Pfam PF02540 NAD synthase 211 264 4.3E-6 T 28-03-2018 IPR022310 NAD/GMP synthase CFK41_RS12515 34ef8a3bd186ca12a1d7b99e33092c29 529 SUPERFAMILY SSF52402 185 449 3.2E-53 T 28-03-2018 CFK41_RS12515 34ef8a3bd186ca12a1d7b99e33092c29 529 SUPERFAMILY SSF54810 408 529 2.22E-46 T 28-03-2018 CFK41_RS12180 3787ffcd18d723166bc7d93ea7ddf0d7 511 SMART SM00342 102 185 7.2E-15 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CFK41_RS12180 3787ffcd18d723166bc7d93ea7ddf0d7 511 SMART SM00478 344 489 3.8E-6 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CFK41_RS12180 3787ffcd18d723166bc7d93ea7ddf0d7 511 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 139 181 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CFK41_RS12180 3787ffcd18d723166bc7d93ea7ddf0d7 511 Gene3D G3DSA:1.10.10.60 140 198 2.7E-8 T 28-03-2018 CFK41_RS12180 3787ffcd18d723166bc7d93ea7ddf0d7 511 Gene3D G3DSA:3.40.10.10 1 74 7.3E-23 T 28-03-2018 IPR035451 Ada-like domain CFK41_RS12180 3787ffcd18d723166bc7d93ea7ddf0d7 511 Gene3D G3DSA:1.10.10.60 85 139 6.6E-5 T 28-03-2018 CFK41_RS12180 3787ffcd18d723166bc7d93ea7ddf0d7 511 SUPERFAMILY SSF55945 205 300 7.69E-17 T 28-03-2018 CFK41_RS12180 3787ffcd18d723166bc7d93ea7ddf0d7 511 Pfam PF02805 Metal binding domain of Ada 9 71 4.6E-27 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CFK41_RS12180 3787ffcd18d723166bc7d93ea7ddf0d7 511 Gene3D G3DSA:1.10.1670.10 441 491 1.2E-7 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CFK41_RS12180 3787ffcd18d723166bc7d93ea7ddf0d7 511 SUPERFAMILY SSF48150 312 486 1.01E-23 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CFK41_RS12180 3787ffcd18d723166bc7d93ea7ddf0d7 511 SUPERFAMILY SSF46689 138 187 1.03E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS12180 3787ffcd18d723166bc7d93ea7ddf0d7 511 SUPERFAMILY SSF57884 2 78 3.01E-29 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CFK41_RS12180 3787ffcd18d723166bc7d93ea7ddf0d7 511 Pfam PF12833 Helix-turn-helix domain 108 187 7.5E-16 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CFK41_RS12180 3787ffcd18d723166bc7d93ea7ddf0d7 511 SMART SM01009 203 322 4.4E-28 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CFK41_RS12180 3787ffcd18d723166bc7d93ea7ddf0d7 511 Pfam PF06029 AlkA N-terminal domain 204 320 5.9E-24 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CFK41_RS12180 3787ffcd18d723166bc7d93ea7ddf0d7 511 Gene3D G3DSA:1.10.340.30 321 438 5.4E-14 T 28-03-2018 CFK41_RS12180 3787ffcd18d723166bc7d93ea7ddf0d7 511 Gene3D G3DSA:3.30.310.20 203 320 2.3E-28 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CFK41_RS15045 508d64d54b063fe0d816843590a2611f 78 Pfam PF00830 Ribosomal L28 family 4 61 6.7E-24 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS15045 508d64d54b063fe0d816843590a2611f 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 6.6E-25 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS15045 508d64d54b063fe0d816843590a2611f 78 SUPERFAMILY SSF143800 2 77 1.12E-26 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS15045 508d64d54b063fe0d816843590a2611f 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 20.289 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS15045 508d64d54b063fe0d816843590a2611f 78 Gene3D G3DSA:2.30.170.40 2 75 7.9E-26 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS16570 d902fd6ef4f83349e49c081c1f78871a 412 SUPERFAMILY SSF54826 12 112 3.24E-30 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS16570 d902fd6ef4f83349e49c081c1f78871a 412 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 85 110 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CFK41_RS16570 d902fd6ef4f83349e49c081c1f78871a 412 Gene3D G3DSA:3.30.390.10 5 100 5.2E-30 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS16570 d902fd6ef4f83349e49c081c1f78871a 412 Pfam PF13378 Enolase C-terminal domain-like 138 387 1.1E-41 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS16570 d902fd6ef4f83349e49c081c1f78871a 412 Gene3D G3DSA:3.20.20.120 101 385 1.9E-60 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS16570 d902fd6ef4f83349e49c081c1f78871a 412 SUPERFAMILY SSF51604 98 394 1.28E-68 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS16570 d902fd6ef4f83349e49c081c1f78871a 412 SMART SM00922 128 267 1.4E-16 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CFK41_RS16570 d902fd6ef4f83349e49c081c1f78871a 412 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 15 110 4.1E-28 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CFK41_RS07135 ca6d125f2978316a2a76dc241af22986 340 Pfam PF00092 von Willebrand factor type A domain 95 297 3.6E-9 T 28-03-2018 IPR002035 von Willebrand factor, type A CFK41_RS07135 ca6d125f2978316a2a76dc241af22986 340 Gene3D G3DSA:3.40.50.410 92 316 1.7E-24 T 28-03-2018 IPR002035 von Willebrand factor, type A CFK41_RS07135 ca6d125f2978316a2a76dc241af22986 340 SMART SM00327 93 299 8.1E-4 T 28-03-2018 IPR002035 von Willebrand factor, type A CFK41_RS07135 ca6d125f2978316a2a76dc241af22986 340 SUPERFAMILY SSF53300 92 161 2.75E-19 T 28-03-2018 IPR002035 von Willebrand factor, type A CFK41_RS07135 ca6d125f2978316a2a76dc241af22986 340 SUPERFAMILY SSF53300 194 300 2.75E-19 T 28-03-2018 IPR002035 von Willebrand factor, type A CFK41_RS10470 2917b075faec49dd9125f9822175e301 306 Gene3D G3DSA:3.40.50.720 4 170 4.6E-15 T 28-03-2018 CFK41_RS10470 2917b075faec49dd9125f9822175e301 306 SUPERFAMILY SSF51735 8 169 2.04E-22 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS10470 2917b075faec49dd9125f9822175e301 306 SUPERFAMILY SSF48179 172 277 3.4E-22 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CFK41_RS10470 2917b075faec49dd9125f9822175e301 306 Pfam PF10728 Domain of unknown function (DUF2520) 139 272 3.8E-38 T 28-03-2018 IPR018931 Domain of unknown function DUF2520 CFK41_RS10470 2917b075faec49dd9125f9822175e301 306 Gene3D G3DSA:1.10.1040.20 172 277 2.9E-33 T 28-03-2018 IPR018931 Domain of unknown function DUF2520 CFK41_RS10470 2917b075faec49dd9125f9822175e301 306 Pfam PF10727 Rossmann-like domain 3 122 7.2E-38 T 28-03-2018 IPR019665 Putative oxidoreductase/dehydrogenase, Rossmann-like domain CFK41_RS12185 dceedd1f36693a413be6397c7e4b116e 181 Gene3D G3DSA:3.30.160.70 21 92 1.7E-15 T 28-03-2018 CFK41_RS12185 dceedd1f36693a413be6397c7e4b116e 181 SUPERFAMILY SSF46767 96 179 5.89E-31 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CFK41_RS12185 dceedd1f36693a413be6397c7e4b116e 181 Gene3D G3DSA:1.10.10.10 93 179 1.3E-35 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS12185 dceedd1f36693a413be6397c7e4b116e 181 SUPERFAMILY SSF53155 24 101 1.0E-15 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CFK41_RS12185 dceedd1f36693a413be6397c7e4b116e 181 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 25 177 40.047 T 28-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 CFK41_RS12185 dceedd1f36693a413be6397c7e4b116e 181 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 147 153 - T 28-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CFK41_RS12185 dceedd1f36693a413be6397c7e4b116e 181 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 97 176 5.7E-33 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CFK41_RS12185 dceedd1f36693a413be6397c7e4b116e 181 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 98 177 1.6E-32 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CFK41_RS07345 6a6fe5da1205eb54301288965c747fb5 272 Gene3D G3DSA:3.40.50.620 2 147 5.9E-27 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS07345 6a6fe5da1205eb54301288965c747fb5 272 PRINTS PR01438 Universal stress protein signature 104 116 8.5E-8 T 28-03-2018 IPR006015 Universal stress protein A CFK41_RS07345 6a6fe5da1205eb54301288965c747fb5 272 PRINTS PR01438 Universal stress protein signature 122 144 8.5E-8 T 28-03-2018 IPR006015 Universal stress protein A CFK41_RS07345 6a6fe5da1205eb54301288965c747fb5 272 SUPERFAMILY SSF52402 8 146 7.45E-23 T 28-03-2018 CFK41_RS07345 6a6fe5da1205eb54301288965c747fb5 272 Gene3D G3DSA:3.40.50.620 153 272 0.002 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS07345 6a6fe5da1205eb54301288965c747fb5 272 Pfam PF00582 Universal stress protein family 8 144 5.9E-19 T 28-03-2018 IPR006016 UspA GO:0006950 CFK41_RS10385 06a18476a795e69182023289b8cac956 304 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 208 224 - T 28-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CFK41_RS10385 06a18476a795e69182023289b8cac956 304 SUPERFAMILY SSF48150 21 233 5.65E-63 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CFK41_RS10385 06a18476a795e69182023289b8cac956 304 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 50 179 1.4E-17 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CFK41_RS10385 06a18476a795e69182023289b8cac956 304 ProSitePatterns PS01155 Endonuclease III family signature. 117 144 - T 28-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 CFK41_RS10385 06a18476a795e69182023289b8cac956 304 Gene3D G3DSA:1.10.1670.10 134 240 2.1E-31 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CFK41_RS10385 06a18476a795e69182023289b8cac956 304 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 208 224 6.1E-5 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CFK41_RS10385 06a18476a795e69182023289b8cac956 304 Gene3D G3DSA:1.10.340.30 35 133 1.5E-29 T 28-03-2018 CFK41_RS10385 06a18476a795e69182023289b8cac956 304 SMART SM00478 54 206 4.9E-30 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CFK41_RS10385 06a18476a795e69182023289b8cac956 304 SMART SM00525 207 227 8.8E-6 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CFK41_RS09910 dc72355508e98d094f46778e0d1783ac 624 Pfam PF03880 DbpA RNA binding domain 511 579 5.4E-18 T 28-03-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain CFK41_RS09910 dc72355508e98d094f46778e0d1783ac 624 Pfam PF00270 DEAD/DEAH box helicase 66 231 7.2E-46 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CFK41_RS09910 dc72355508e98d094f46778e0d1783ac 624 Gene3D G3DSA:3.40.50.300 14 256 2.8E-59 T 28-03-2018 CFK41_RS09910 dc72355508e98d094f46778e0d1783ac 624 SMART SM00490 294 375 8.7E-29 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS09910 dc72355508e98d094f46778e0d1783ac 624 Pfam PF00271 Helicase conserved C-terminal domain 275 375 7.5E-26 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS09910 dc72355508e98d094f46778e0d1783ac 624 SUPERFAMILY SSF52540 109 396 1.99E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS09910 dc72355508e98d094f46778e0d1783ac 624 Gene3D G3DSA:3.40.50.300 257 408 1.2E-40 T 28-03-2018 CFK41_RS09910 dc72355508e98d094f46778e0d1783ac 624 SMART SM00487 60 258 1.0E-61 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CFK41_RS09910 dc72355508e98d094f46778e0d1783ac 624 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 189 197 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CFK41_RS06045 1e3d9a7e99f6801a61d397e83e650c47 435 Pfam PF00591 Glycosyl transferase family, a/b domain 87 303 1.1E-32 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CFK41_RS06045 1e3d9a7e99f6801a61d397e83e650c47 435 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 14 416 9.4E-166 T 28-03-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 CFK41_RS06045 1e3d9a7e99f6801a61d397e83e650c47 435 PIRSF PIRSF000478 10 431 1.7E-147 T 28-03-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CFK41_RS06045 1e3d9a7e99f6801a61d397e83e650c47 435 SUPERFAMILY SSF47648 11 79 2.22E-19 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CFK41_RS06045 1e3d9a7e99f6801a61d397e83e650c47 435 SUPERFAMILY SSF54680 331 421 1.44E-22 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CFK41_RS06045 1e3d9a7e99f6801a61d397e83e650c47 435 Gene3D G3DSA:3.40.1030.10 78 335 1.3E-81 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CFK41_RS06045 1e3d9a7e99f6801a61d397e83e650c47 435 Gene3D G3DSA:1.20.970.10 8 77 3.2E-21 T 28-03-2018 CFK41_RS06045 1e3d9a7e99f6801a61d397e83e650c47 435 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 120 135 - T 28-03-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CFK41_RS06045 1e3d9a7e99f6801a61d397e83e650c47 435 SUPERFAMILY SSF52418 79 326 1.44E-78 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CFK41_RS06045 1e3d9a7e99f6801a61d397e83e650c47 435 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 344 416 1.9E-19 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CFK41_RS06045 1e3d9a7e99f6801a61d397e83e650c47 435 Pfam PF02885 Glycosyl transferase family, helical bundle domain 14 76 7.1E-17 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CFK41_RS06045 1e3d9a7e99f6801a61d397e83e650c47 435 SMART SM00941 344 418 2.8E-27 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CFK41_RS06045 1e3d9a7e99f6801a61d397e83e650c47 435 Gene3D G3DSA:3.90.1170.30 336 420 1.8E-26 T 28-03-2018 CFK41_RS14940 3cb059d0b438d079034b5bc47e4daa89 291 Pfam PF00561 alpha/beta hydrolase fold 30 274 7.0E-25 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CFK41_RS14940 3cb059d0b438d079034b5bc47e4daa89 291 Gene3D G3DSA:3.40.50.1820 1 291 4.2E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS14940 3cb059d0b438d079034b5bc47e4daa89 291 SUPERFAMILY SSF53474 12 289 1.18E-50 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS14940 3cb059d0b438d079034b5bc47e4daa89 291 PRINTS PR00111 Alpha/beta hydrolase fold signature 57 72 3.0E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CFK41_RS14940 3cb059d0b438d079034b5bc47e4daa89 291 PRINTS PR00111 Alpha/beta hydrolase fold signature 115 128 3.0E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CFK41_RS14940 3cb059d0b438d079034b5bc47e4daa89 291 PRINTS PR00111 Alpha/beta hydrolase fold signature 101 114 3.0E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CFK41_RS00390 7f1bd41ff728e5e84d77ad2403822fa0 217 Gene3D G3DSA:3.40.50.1820 1 217 4.9E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS00390 7f1bd41ff728e5e84d77ad2403822fa0 217 Pfam PF12697 Alpha/beta hydrolase family 6 212 1.8E-15 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CFK41_RS00390 7f1bd41ff728e5e84d77ad2403822fa0 217 SUPERFAMILY SSF53474 4 216 6.68E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS01795 d4e84fec47d7a74b07f116c94fbed18e 282 SUPERFAMILY SSF51197 22 245 5.01E-48 T 28-03-2018 CFK41_RS01795 d4e84fec47d7a74b07f116c94fbed18e 282 Gene3D G3DSA:2.60.120.620 6 253 1.6E-43 T 28-03-2018 CFK41_RS01795 d4e84fec47d7a74b07f116c94fbed18e 282 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 29 233 1.6E-35 T 28-03-2018 IPR008775 Phytanoyl-CoA dioxygenase CFK41_RS07105 c4e3f5225bfcfd4f401d084c2f191e2d 744 SUPERFAMILY SSF51445 267 631 1.69E-108 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS07105 c4e3f5225bfcfd4f401d084c2f191e2d 744 SUPERFAMILY SSF51011 637 740 6.99E-31 T 28-03-2018 CFK41_RS07105 c4e3f5225bfcfd4f401d084c2f191e2d 744 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 128 737 1.7E-277 T 28-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 CFK41_RS07105 c4e3f5225bfcfd4f401d084c2f191e2d 744 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 642 739 1.7E-18 T 28-03-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CFK41_RS07105 c4e3f5225bfcfd4f401d084c2f191e2d 744 Gene3D G3DSA:2.60.40.1180 650 740 2.6E-33 T 28-03-2018 CFK41_RS07105 c4e3f5225bfcfd4f401d084c2f191e2d 744 SMART SM00642 269 624 2.0E-7 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CFK41_RS07105 c4e3f5225bfcfd4f401d084c2f191e2d 744 PIRSF PIRSF000463 28 744 5.4E-285 T 28-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 CFK41_RS07105 c4e3f5225bfcfd4f401d084c2f191e2d 744 Gene3D G3DSA:2.60.40.10 124 242 1.1E-30 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS07105 c4e3f5225bfcfd4f401d084c2f191e2d 744 Gene3D G3DSA:2.60.40.10 23 123 7.2E-12 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS07105 c4e3f5225bfcfd4f401d084c2f191e2d 744 Pfam PF00128 Alpha amylase, catalytic domain 290 358 1.2E-7 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CFK41_RS07105 c4e3f5225bfcfd4f401d084c2f191e2d 744 Gene3D G3DSA:3.20.20.80 255 649 1.4E-74 T 28-03-2018 CFK41_RS07105 c4e3f5225bfcfd4f401d084c2f191e2d 744 SUPERFAMILY SSF81296 136 242 2.97E-31 T 28-03-2018 IPR014756 Immunoglobulin E-set CFK41_RS07105 c4e3f5225bfcfd4f401d084c2f191e2d 744 SUPERFAMILY SSF81296 37 133 5.2E-17 T 28-03-2018 IPR014756 Immunoglobulin E-set CFK41_RS07105 c4e3f5225bfcfd4f401d084c2f191e2d 744 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 144 226 6.7E-20 T 28-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 CFK41_RS07105 c4e3f5225bfcfd4f401d084c2f191e2d 744 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 120 740 43.39 T 28-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 CFK41_RS08495 1e7c27dfd0938cf8105a05469417578c 476 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 97 2.4E-26 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CFK41_RS08495 1e7c27dfd0938cf8105a05469417578c 476 SUPERFAMILY SSF55931 105 475 3.92E-139 T 28-03-2018 CFK41_RS08495 1e7c27dfd0938cf8105a05469417578c 476 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 28-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CFK41_RS08495 1e7c27dfd0938cf8105a05469417578c 476 Pfam PF00120 Glutamine synthetase, catalytic domain 105 473 8.5E-136 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CFK41_RS08495 1e7c27dfd0938cf8105a05469417578c 476 SMART SM01230 104 385 6.2E-151 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CFK41_RS08495 1e7c27dfd0938cf8105a05469417578c 476 Gene3D G3DSA:3.10.20.70 4 106 1.3E-26 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CFK41_RS08495 1e7c27dfd0938cf8105a05469417578c 476 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 475 1.1E-200 T 28-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CFK41_RS08495 1e7c27dfd0938cf8105a05469417578c 476 SUPERFAMILY SSF54368 5 103 7.85E-33 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CFK41_RS08495 1e7c27dfd0938cf8105a05469417578c 476 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 263 278 - T 28-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CFK41_RS08495 1e7c27dfd0938cf8105a05469417578c 476 Gene3D G3DSA:3.30.590.10 107 461 7.0E-125 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CFK41_RS17515 6242175fad0ba95b26bde6c5f61de612 618 SMART SM00470 346 440 9.9E-33 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CFK41_RS17515 6242175fad0ba95b26bde6c5f61de612 618 Gene3D G3DSA:1.10.10.730 441 488 2.3E-18 T 28-03-2018 CFK41_RS17515 6242175fad0ba95b26bde6c5f61de612 618 SUPERFAMILY SSF109709 432 539 1.23E-32 T 28-03-2018 CFK41_RS17515 6242175fad0ba95b26bde6c5f61de612 618 SUPERFAMILY SSF110849 338 443 6.28E-29 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CFK41_RS17515 6242175fad0ba95b26bde6c5f61de612 618 Pfam PF02195 ParB-like nuclease domain 347 439 4.3E-22 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CFK41_RS17515 6242175fad0ba95b26bde6c5f61de612 618 Gene3D G3DSA:3.90.1530.10 337 440 2.3E-35 T 28-03-2018 CFK41_RS17515 6242175fad0ba95b26bde6c5f61de612 618 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 344 525 6.5E-55 T 28-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CFK41_RS11745 005b8b10e25d9a86bd96cee4fd410cd8 957 Pfam PF11987 Translation-initiation factor 2 742 847 6.1E-28 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CFK41_RS11745 005b8b10e25d9a86bd96cee4fd410cd8 957 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 361 955 2.1E-227 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CFK41_RS11745 005b8b10e25d9a86bd96cee4fd410cd8 957 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 2 51 4.7E-12 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CFK41_RS11745 005b8b10e25d9a86bd96cee4fd410cd8 957 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 368 415 9.0E-9 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CFK41_RS11745 005b8b10e25d9a86bd96cee4fd410cd8 957 SUPERFAMILY SSF52156 737 864 6.15E-31 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CFK41_RS11745 005b8b10e25d9a86bd96cee4fd410cd8 957 PRINTS PR00315 GTP-binding elongation factor signature 522 533 1.3E-9 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS11745 005b8b10e25d9a86bd96cee4fd410cd8 957 PRINTS PR00315 GTP-binding elongation factor signature 454 467 1.3E-9 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS11745 005b8b10e25d9a86bd96cee4fd410cd8 957 PRINTS PR00315 GTP-binding elongation factor signature 558 567 1.3E-9 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS11745 005b8b10e25d9a86bd96cee4fd410cd8 957 PRINTS PR00315 GTP-binding elongation factor signature 506 516 1.3E-9 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS11745 005b8b10e25d9a86bd96cee4fd410cd8 957 Pfam PF00009 Elongation factor Tu GTP binding domain 455 615 3.6E-34 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS11745 005b8b10e25d9a86bd96cee4fd410cd8 957 SUPERFAMILY SSF50447 858 956 7.69E-26 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CFK41_RS11745 005b8b10e25d9a86bd96cee4fd410cd8 957 SUPERFAMILY SSF50447 628 710 4.52E-24 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CFK41_RS11745 005b8b10e25d9a86bd96cee4fd410cd8 957 Gene3D G3DSA:3.40.50.300 445 630 1.1E-38 T 28-03-2018 CFK41_RS11745 005b8b10e25d9a86bd96cee4fd410cd8 957 Gene3D G3DSA:2.40.30.10 858 957 6.0E-24 T 28-03-2018 CFK41_RS11745 005b8b10e25d9a86bd96cee4fd410cd8 957 SUPERFAMILY SSF52540 446 617 1.54E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11745 005b8b10e25d9a86bd96cee4fd410cd8 957 Gene3D G3DSA:3.30.56.50 368 408 6.2E-4 T 28-03-2018 CFK41_RS11745 005b8b10e25d9a86bd96cee4fd410cd8 957 Gene3D G3DSA:3.30.56.50 4 46 1.6E-10 T 28-03-2018 CFK41_RS11745 005b8b10e25d9a86bd96cee4fd410cd8 957 Gene3D G3DSA:2.40.30.10 631 756 3.7E-33 T 28-03-2018 CFK41_RS11745 005b8b10e25d9a86bd96cee4fd410cd8 957 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 956 16.573 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CFK41_RS11745 005b8b10e25d9a86bd96cee4fd410cd8 957 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 453 613 5.7E-31 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CFK41_RS11745 005b8b10e25d9a86bd96cee4fd410cd8 957 Gene3D G3DSA:3.40.50.10050 757 836 1.8E-18 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CFK41_RS00940 f0a89c004b150d69c8d749dc9fe5773e 405 Gene3D G3DSA:3.40.47.10 280 401 2.2E-32 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CFK41_RS00940 f0a89c004b150d69c8d749dc9fe5773e 405 ProSitePatterns PS00099 Thiolases active site. 385 398 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CFK41_RS00940 f0a89c004b150d69c8d749dc9fe5773e 405 Gene3D G3DSA:3.40.47.10 2 279 8.8E-52 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CFK41_RS00940 f0a89c004b150d69c8d749dc9fe5773e 405 PIRSF PIRSF000429 2 405 1.2E-126 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CFK41_RS00940 f0a89c004b150d69c8d749dc9fe5773e 405 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 402 1.6E-133 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CFK41_RS00940 f0a89c004b150d69c8d749dc9fe5773e 405 SUPERFAMILY SSF53901 282 403 1.92E-43 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CFK41_RS00940 f0a89c004b150d69c8d749dc9fe5773e 405 ProSitePatterns PS00737 Thiolases signature 2. 350 366 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CFK41_RS00940 f0a89c004b150d69c8d749dc9fe5773e 405 SUPERFAMILY SSF53901 3 281 2.05E-66 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CFK41_RS00940 f0a89c004b150d69c8d749dc9fe5773e 405 Pfam PF00108 Thiolase, N-terminal domain 5 273 9.7E-63 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CFK41_RS00940 f0a89c004b150d69c8d749dc9fe5773e 405 Pfam PF02803 Thiolase, C-terminal domain 282 403 1.2E-45 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CFK41_RS11945 054e17a0b518af8a30157795528c0a62 781 Gene3D G3DSA:3.30.460.10 26 147 1.3E-10 T 28-03-2018 CFK41_RS11945 054e17a0b518af8a30157795528c0a62 781 SMART SM00471 412 546 1.4E-6 T 28-03-2018 IPR003607 HD/PDEase domain CFK41_RS11945 054e17a0b518af8a30157795528c0a62 781 SUPERFAMILY SSF81301 32 152 1.23E-10 T 28-03-2018 CFK41_RS11945 054e17a0b518af8a30157795528c0a62 781 SUPERFAMILY SSF81593 169 277 4.87E-5 T 28-03-2018 CFK41_RS11945 054e17a0b518af8a30157795528c0a62 781 SUPERFAMILY SSF109604 385 551 1.57E-12 T 28-03-2018 CFK41_RS11945 054e17a0b518af8a30157795528c0a62 781 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 781 56.921 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CFK41_RS11945 054e17a0b518af8a30157795528c0a62 781 Gene3D G3DSA:1.20.120.330 203 285 0.009 T 28-03-2018 CFK41_RS11945 054e17a0b518af8a30157795528c0a62 781 Gene3D G3DSA:1.20.120.330 148 202 0.011 T 28-03-2018 CFK41_RS11945 054e17a0b518af8a30157795528c0a62 781 Gene3D G3DSA:1.10.3090.10 320 588 2.3E-32 T 28-03-2018 CFK41_RS11945 054e17a0b518af8a30157795528c0a62 781 Gene3D G3DSA:3.30.70.260 705 781 6.5E-8 T 28-03-2018 CFK41_RS11945 054e17a0b518af8a30157795528c0a62 781 Gene3D G3DSA:3.30.70.260 600 683 1.9E-6 T 28-03-2018 CFK41_RS11945 054e17a0b518af8a30157795528c0a62 781 Pfam PF01966 HD domain 417 495 3.7E-5 T 28-03-2018 IPR006674 HD domain CFK41_RS11945 054e17a0b518af8a30157795528c0a62 781 SUPERFAMILY SSF55021 707 774 5.72E-6 T 28-03-2018 CFK41_RS11945 054e17a0b518af8a30157795528c0a62 781 PIRSF PIRSF006288 4 594 4.5E-103 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CFK41_RS11945 054e17a0b518af8a30157795528c0a62 781 PIRSF PIRSF006288 584 781 9.4E-26 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CFK41_RS01760 116de6fa4064d2f13ffeac29678bf93c 511 SUPERFAMILY SSF51126 82 373 1.43E-55 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CFK41_RS01760 116de6fa4064d2f13ffeac29678bf93c 511 Gene3D G3DSA:2.160.20.10 375 508 2.8E-15 T 28-03-2018 IPR012334 Pectin lyase fold CFK41_RS01760 116de6fa4064d2f13ffeac29678bf93c 511 SMART SM00656 104 315 4.1E-14 T 28-03-2018 IPR002022 Pectate lyase CFK41_RS01760 116de6fa4064d2f13ffeac29678bf93c 511 Gene3D G3DSA:2.160.20.10 139 374 6.9E-45 T 28-03-2018 IPR012334 Pectin lyase fold CFK41_RS01760 116de6fa4064d2f13ffeac29678bf93c 511 Gene3D G3DSA:2.160.20.10 78 138 2.8E-6 T 28-03-2018 IPR012334 Pectin lyase fold CFK41_RS01760 116de6fa4064d2f13ffeac29678bf93c 511 Pfam PF00544 Pectate lyase 140 309 4.3E-19 T 28-03-2018 IPR002022 Pectate lyase CFK41_RS01760 116de6fa4064d2f13ffeac29678bf93c 511 SUPERFAMILY SSF51126 377 507 9.68E-17 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CFK41_RS13980 472a26f12e6c8094339bbb8e79415f79 358 SUPERFAMILY SSF51604 97 355 2.72E-41 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS13980 472a26f12e6c8094339bbb8e79415f79 358 Gene3D G3DSA:3.30.390.10 4 70 0.0067 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS13980 472a26f12e6c8094339bbb8e79415f79 358 SUPERFAMILY SSF54826 28 109 4.95E-10 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS13980 472a26f12e6c8094339bbb8e79415f79 358 Gene3D G3DSA:3.30.390.10 71 114 5.6E-8 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS13980 472a26f12e6c8094339bbb8e79415f79 358 SMART SM00922 137 240 1.7E-19 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CFK41_RS13980 472a26f12e6c8094339bbb8e79415f79 358 Pfam PF13378 Enolase C-terminal domain-like 147 355 3.6E-37 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS13980 472a26f12e6c8094339bbb8e79415f79 358 Gene3D G3DSA:3.20.20.120 115 356 3.2E-41 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS16205 6f78a113dcf0a4e275427594577e3a57 452 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 176 1.2E-46 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CFK41_RS16205 6f78a113dcf0a4e275427594577e3a57 452 SMART SM00984 324 425 7.6E-36 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CFK41_RS16205 6f78a113dcf0a4e275427594577e3a57 452 Gene3D G3DSA:1.20.5.100 210 230 2.0E-13 T 28-03-2018 CFK41_RS16205 6f78a113dcf0a4e275427594577e3a57 452 SUPERFAMILY SSF52413 312 434 3.66E-34 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CFK41_RS16205 6f78a113dcf0a4e275427594577e3a57 452 Gene3D G3DSA:3.40.50.720 231 436 5.5E-69 T 28-03-2018 CFK41_RS16205 6f78a113dcf0a4e275427594577e3a57 452 PIRSF PIRSF000124 1 440 7.0E-116 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CFK41_RS16205 6f78a113dcf0a4e275427594577e3a57 452 Gene3D G3DSA:3.40.50.720 1 209 1.0E-46 T 28-03-2018 CFK41_RS16205 6f78a113dcf0a4e275427594577e3a57 452 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 421 1.5E-115 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CFK41_RS16205 6f78a113dcf0a4e275427594577e3a57 452 SUPERFAMILY SSF48179 207 304 2.72E-28 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CFK41_RS16205 6f78a113dcf0a4e275427594577e3a57 452 SUPERFAMILY SSF51735 3 198 3.27E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS16205 6f78a113dcf0a4e275427594577e3a57 452 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 325 425 3.5E-27 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CFK41_RS16205 6f78a113dcf0a4e275427594577e3a57 452 PIRSF PIRSF500134 1 443 1.1E-141 T 28-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 CFK41_RS16205 6f78a113dcf0a4e275427594577e3a57 452 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 207 301 3.3E-33 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CFK41_RS15335 9fcf500efde1149e3667a25056205bcb 295 Pfam PF01063 Amino-transferase class IV 49 271 8.1E-38 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CFK41_RS15335 9fcf500efde1149e3667a25056205bcb 295 Gene3D G3DSA:3.20.10.10 134 289 6.6E-33 T 28-03-2018 CFK41_RS15335 9fcf500efde1149e3667a25056205bcb 295 SUPERFAMILY SSF56752 32 290 1.07E-51 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CFK41_RS15335 9fcf500efde1149e3667a25056205bcb 295 Gene3D G3DSA:3.30.470.10 25 128 2.0E-22 T 28-03-2018 CFK41_RS04840 ce5405b50f51aedb00cce9ecf4622683 90 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 11 70 5.0E-15 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CFK41_RS04840 ce5405b50f51aedb00cce9ecf4622683 90 SUPERFAMILY SSF82697 2 75 1.06E-22 T 28-03-2018 CFK41_RS04840 ce5405b50f51aedb00cce9ecf4622683 90 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 75 2.2E-26 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CFK41_RS04840 ce5405b50f51aedb00cce9ecf4622683 90 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 79 19.687 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CFK41_RS04840 ce5405b50f51aedb00cce9ecf4622683 90 Gene3D G3DSA:3.30.1280.10 1 81 1.7E-26 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CFK41_RS04840 ce5405b50f51aedb00cce9ecf4622683 90 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 75 1.2E-15 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CFK41_RS00370 10cba06ed0783d016192083ff39bf6f8 239 Pfam PF12833 Helix-turn-helix domain 157 231 1.1E-10 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CFK41_RS00370 10cba06ed0783d016192083ff39bf6f8 239 SMART SM00342 151 231 0.0013 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CFK41_RS00370 10cba06ed0783d016192083ff39bf6f8 239 Gene3D G3DSA:1.10.10.60 108 187 2.3E-5 T 28-03-2018 CFK41_RS00370 10cba06ed0783d016192083ff39bf6f8 239 Gene3D G3DSA:1.10.10.60 188 237 3.2E-4 T 28-03-2018 CFK41_RS08570 0d482575380a9d91383fbe20e380b8ad 183 Pfam PF03652 Holliday junction resolvase 19 152 3.1E-36 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CFK41_RS08570 0d482575380a9d91383fbe20e380b8ad 183 Gene3D G3DSA:3.30.420.140 16 165 1.1E-40 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CFK41_RS08570 0d482575380a9d91383fbe20e380b8ad 183 SUPERFAMILY SSF53098 18 153 2.85E-30 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CFK41_RS08570 0d482575380a9d91383fbe20e380b8ad 183 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 21 152 4.0E-24 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CFK41_RS08570 0d482575380a9d91383fbe20e380b8ad 183 SMART SM00732 18 120 3.1E-18 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CFK41_RS08570 0d482575380a9d91383fbe20e380b8ad 183 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 18 155 20.66 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CFK41_RS16285 935a6bb0db9c9a6ff50bd7695d042443 347 SUPERFAMILY SSF161098 100 328 4.32E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS16285 935a6bb0db9c9a6ff50bd7695d042443 347 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 132 301 1.5E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS16285 935a6bb0db9c9a6ff50bd7695d042443 347 Gene3D G3DSA:1.10.3720.10 56 343 3.2E-38 T 28-03-2018 CFK41_RS01855 09011ad040974f49f7642c4a9b24d383 329 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 119 289 3.4E-36 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CFK41_RS01855 09011ad040974f49f7642c4a9b24d383 329 SUPERFAMILY SSF51735 109 290 4.51E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS01855 09011ad040974f49f7642c4a9b24d383 329 Gene3D G3DSA:3.40.50.720 120 291 1.4E-37 T 28-03-2018 CFK41_RS01855 09011ad040974f49f7642c4a9b24d383 329 SUPERFAMILY SSF52283 29 136 2.34E-8 T 28-03-2018 CFK41_RS01855 09011ad040974f49f7642c4a9b24d383 329 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 45 320 1.9E-7 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CFK41_RS01855 09011ad040974f49f7642c4a9b24d383 329 Gene3D G3DSA:3.40.50.720 7 119 6.6E-17 T 28-03-2018 CFK41_RS01855 09011ad040974f49f7642c4a9b24d383 329 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 202 224 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CFK41_RS09515 0ed0f142381793fe70934b50f8e116a1 287 Gene3D G3DSA:3.20.20.70 13 287 4.1E-80 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS09515 0ed0f142381793fe70934b50f8e116a1 287 SMART SM00934 27 278 3.6E-27 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CFK41_RS09515 0ed0f142381793fe70934b50f8e116a1 287 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 14 277 1.1E-76 T 28-03-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CFK41_RS09515 0ed0f142381793fe70934b50f8e116a1 287 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 101 114 - T 28-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CFK41_RS09515 0ed0f142381793fe70934b50f8e116a1 287 SUPERFAMILY SSF51366 14 285 9.42E-60 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CFK41_RS09515 0ed0f142381793fe70934b50f8e116a1 287 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 60 276 6.9E-30 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CFK41_RS09880 28c23359d50c915b36666e11a8313f3b 312 PRINTS PR01166 Cytochrome c oxidase subunit II signature 197 217 1.0E-9 T 28-03-2018 CFK41_RS09880 28c23359d50c915b36666e11a8313f3b 312 PRINTS PR01166 Cytochrome c oxidase subunit II signature 235 252 1.0E-9 T 28-03-2018 CFK41_RS09880 28c23359d50c915b36666e11a8313f3b 312 PRINTS PR01166 Cytochrome c oxidase subunit II signature 134 153 1.0E-9 T 28-03-2018 CFK41_RS09880 28c23359d50c915b36666e11a8313f3b 312 PRINTS PR01166 Cytochrome c oxidase subunit II signature 217 234 1.0E-9 T 28-03-2018 CFK41_RS09880 28c23359d50c915b36666e11a8313f3b 312 PRINTS PR01166 Cytochrome c oxidase subunit II signature 99 111 1.0E-9 T 28-03-2018 CFK41_RS09880 28c23359d50c915b36666e11a8313f3b 312 SUPERFAMILY SSF49503 133 271 4.26E-41 T 28-03-2018 IPR008972 Cupredoxin CFK41_RS09880 28c23359d50c915b36666e11a8313f3b 312 SUPERFAMILY SSF81464 23 124 1.14E-14 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS09880 28c23359d50c915b36666e11a8313f3b 312 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 52 263 2.1E-48 T 28-03-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS09880 28c23359d50c915b36666e11a8313f3b 312 Gene3D G3DSA:2.60.40.420 127 302 5.9E-46 T 28-03-2018 IPR008972 Cupredoxin CFK41_RS09880 28c23359d50c915b36666e11a8313f3b 312 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 139 250 8.4E-16 T 28-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS09880 28c23359d50c915b36666e11a8313f3b 312 Gene3D G3DSA:1.10.287.90 45 126 5.9E-14 T 28-03-2018 CFK41_RS09880 28c23359d50c915b36666e11a8313f3b 312 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 198 246 - T 28-03-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS17120 1eb49acd44b2a1fdc92dba7cf5a9ecae 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 192 1.8E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17120 1eb49acd44b2a1fdc92dba7cf5a9ecae 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 18 35 1.8E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17120 1eb49acd44b2a1fdc92dba7cf5a9ecae 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 97 108 1.8E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17120 1eb49acd44b2a1fdc92dba7cf5a9ecae 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 228 248 1.8E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17120 1eb49acd44b2a1fdc92dba7cf5a9ecae 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 1.8E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17120 1eb49acd44b2a1fdc92dba7cf5a9ecae 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 211 1.8E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17120 1eb49acd44b2a1fdc92dba7cf5a9ecae 267 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 265 6.6E-61 T 28-03-2018 CFK41_RS17120 1eb49acd44b2a1fdc92dba7cf5a9ecae 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 173 192 1.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17120 1eb49acd44b2a1fdc92dba7cf5a9ecae 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 97 108 1.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17120 1eb49acd44b2a1fdc92dba7cf5a9ecae 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 159 1.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17120 1eb49acd44b2a1fdc92dba7cf5a9ecae 267 SUPERFAMILY SSF51735 15 266 3.51E-75 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS17120 1eb49acd44b2a1fdc92dba7cf5a9ecae 267 Gene3D G3DSA:3.40.50.720 2 267 2.7E-70 T 28-03-2018 CFK41_RS09810 09a54ab993252437f316ea0e877dbfa1 256 SUPERFAMILY SSF53474 16 249 1.37E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS09810 09a54ab993252437f316ea0e877dbfa1 256 Gene3D G3DSA:3.40.50.1820 7 251 1.9E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS09810 09a54ab993252437f316ea0e877dbfa1 256 Pfam PF12146 Serine aminopeptidase, S33 17 213 2.5E-11 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CFK41_RS09810 09a54ab993252437f316ea0e877dbfa1 256 PIRSF PIRSF017388 9 251 8.9E-51 T 28-03-2018 IPR012354 Esterase/lipase GO:0052689 CFK41_RS02355 312045bcc99bf8e6a6e8a2916697bf39 254 SUPERFAMILY SSF55729 134 229 1.89E-15 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS02355 312045bcc99bf8e6a6e8a2916697bf39 254 Gene3D G3DSA:3.40.630.30 10 245 1.4E-14 T 28-03-2018 CFK41_RS02355 312045bcc99bf8e6a6e8a2916697bf39 254 Pfam PF00583 Acetyltransferase (GNAT) family 144 224 8.3E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS06925 2761d2b5a783dab658a91fb29cc7c5c6 275 SMART SM00862 167 238 5.5E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CFK41_RS06925 2761d2b5a783dab658a91fb29cc7c5c6 275 Pfam PF00072 Response regulator receiver domain 17 125 1.6E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS06925 2761d2b5a783dab658a91fb29cc7c5c6 275 SUPERFAMILY SSF46894 148 239 1.5E-26 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CFK41_RS06925 2761d2b5a783dab658a91fb29cc7c5c6 275 SMART SM00448 15 125 9.4E-40 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS06925 2761d2b5a783dab658a91fb29cc7c5c6 275 Gene3D G3DSA:3.40.50.2300 1 140 2.0E-36 T 28-03-2018 CFK41_RS06925 2761d2b5a783dab658a91fb29cc7c5c6 275 Pfam PF00486 Transcriptional regulatory protein, C terminal 169 238 5.1E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CFK41_RS06925 2761d2b5a783dab658a91fb29cc7c5c6 275 SUPERFAMILY SSF52172 10 140 1.42E-39 T 28-03-2018 IPR011006 CheY-like superfamily CFK41_RS06925 2761d2b5a783dab658a91fb29cc7c5c6 275 Gene3D G3DSA:1.10.10.10 141 245 1.6E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS02420 03a94fba487c52d75df8aed8b1dcb0e8 600 Pfam PF13579 Glycosyl transferase 4-like domain 189 370 6.1E-19 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CFK41_RS02420 03a94fba487c52d75df8aed8b1dcb0e8 600 Gene3D G3DSA:3.40.50.2000 383 572 4.3E-29 T 28-03-2018 CFK41_RS02420 03a94fba487c52d75df8aed8b1dcb0e8 600 Gene3D G3DSA:3.40.50.2000 173 382 1.2E-13 T 28-03-2018 CFK41_RS02420 03a94fba487c52d75df8aed8b1dcb0e8 600 SUPERFAMILY SSF53756 175 588 1.21E-52 T 28-03-2018 CFK41_RS02420 03a94fba487c52d75df8aed8b1dcb0e8 600 Pfam PF13692 Glycosyl transferases group 1 399 554 4.4E-20 T 28-03-2018 CFK41_RS09760 cb4068c0ba3a228169b577532f250010 178 SUPERFAMILY SSF55729 9 158 3.01E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS09760 cb4068c0ba3a228169b577532f250010 178 Gene3D G3DSA:3.40.630.30 1 176 1.3E-27 T 28-03-2018 CFK41_RS09760 cb4068c0ba3a228169b577532f250010 178 Pfam PF13673 Acetyltransferase (GNAT) domain 48 169 7.0E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS00250 f1c3b277929643f5c49551c295be472b 662 SUPERFAMILY SSF56235 2 653 2.57E-119 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CFK41_RS00250 f1c3b277929643f5c49551c295be472b 662 Gene3D G3DSA:3.60.20.10 153 245 2.0E-19 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CFK41_RS00250 f1c3b277929643f5c49551c295be472b 662 Gene3D G3DSA:1.10.1400.10 429 595 1.1E-20 T 28-03-2018 CFK41_RS00250 f1c3b277929643f5c49551c295be472b 662 Gene3D G3DSA:1.10.439.10 1 142 5.7E-22 T 28-03-2018 IPR023343 Penicillin amidase type, domain1 GO:0016811 CFK41_RS00250 f1c3b277929643f5c49551c295be472b 662 Gene3D G3DSA:3.60.20.10 246 428 3.4E-28 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CFK41_RS00250 f1c3b277929643f5c49551c295be472b 662 Pfam PF01804 Penicillin amidase 2 629 1.1E-89 T 28-03-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 CFK41_RS07660 7c8421259f595d04ae9c505d612efb45 548 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 92 470 3.5E-67 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CFK41_RS07660 7c8421259f595d04ae9c505d612efb45 548 PIRSF PIRSF002741 7 544 4.1E-63 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CFK41_RS07660 7c8421259f595d04ae9c505d612efb45 548 Gene3D G3DSA:3.40.190.10 202 308 9.1E-15 T 28-03-2018 CFK41_RS07660 7c8421259f595d04ae9c505d612efb45 548 Gene3D G3DSA:3.90.76.10 56 197 2.5E-30 T 28-03-2018 CFK41_RS07660 7c8421259f595d04ae9c505d612efb45 548 Gene3D G3DSA:3.10.105.10 309 521 2.1E-40 T 28-03-2018 CFK41_RS07660 7c8421259f595d04ae9c505d612efb45 548 SUPERFAMILY SSF53850 43 543 5.97E-99 T 28-03-2018 CFK41_RS00300 fcbbf945a78f159d7b382c7a8aec4c95 503 SUPERFAMILY SSF53474 87 139 7.16E-19 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS00300 fcbbf945a78f159d7b382c7a8aec4c95 503 SUPERFAMILY SSF53474 394 487 7.16E-19 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS00300 fcbbf945a78f159d7b382c7a8aec4c95 503 SUPERFAMILY SSF53474 183 255 7.16E-19 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS00300 fcbbf945a78f159d7b382c7a8aec4c95 503 Pfam PF00561 alpha/beta hydrolase fold 90 475 2.8E-34 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CFK41_RS00300 fcbbf945a78f159d7b382c7a8aec4c95 503 Gene3D G3DSA:3.40.50.1820 72 493 3.7E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS16685 98716953833a985adcb1f677c8b4bcf6 849 PIRSF PIRSF037149 1 831 0.0 T 28-03-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 CFK41_RS16685 98716953833a985adcb1f677c8b4bcf6 849 PRINTS PR00397 Sirohaem Fe-binding site signature 674 692 4.5E-6 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CFK41_RS16685 98716953833a985adcb1f677c8b4bcf6 849 PRINTS PR00397 Sirohaem Fe-binding site signature 631 649 4.5E-6 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CFK41_RS16685 98716953833a985adcb1f677c8b4bcf6 849 SUPERFAMILY SSF51905 1 185 2.02E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS16685 98716953833a985adcb1f677c8b4bcf6 849 SUPERFAMILY SSF51905 141 310 2.43E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS16685 98716953833a985adcb1f677c8b4bcf6 849 SUPERFAMILY SSF56014 628 799 1.57E-44 T 28-03-2018 CFK41_RS16685 98716953833a985adcb1f677c8b4bcf6 849 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 1 795 2.4E-293 T 28-03-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 CFK41_RS16685 98716953833a985adcb1f677c8b4bcf6 849 Gene3D G3DSA:3.30.413.10 626 806 3.9E-36 T 28-03-2018 CFK41_RS16685 98716953833a985adcb1f677c8b4bcf6 849 Gene3D G3DSA:3.90.480.10 391 624 1.5E-7 T 28-03-2018 CFK41_RS16685 98716953833a985adcb1f677c8b4bcf6 849 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 555 616 1.7E-10 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CFK41_RS16685 98716953833a985adcb1f677c8b4bcf6 849 Pfam PF04324 BFD-like [2Fe-2S] binding domain 417 465 1.1E-9 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CFK41_RS16685 98716953833a985adcb1f677c8b4bcf6 849 Gene3D G3DSA:3.50.50.60 244 313 4.7E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS16685 98716953833a985adcb1f677c8b4bcf6 849 Gene3D G3DSA:3.50.50.60 108 243 1.7E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS16685 98716953833a985adcb1f677c8b4bcf6 849 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 1.7E-19 T 28-03-2018 CFK41_RS16685 98716953833a985adcb1f677c8b4bcf6 849 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 1 11 1.7E-19 T 28-03-2018 CFK41_RS16685 98716953833a985adcb1f677c8b4bcf6 849 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 1.7E-19 T 28-03-2018 CFK41_RS16685 98716953833a985adcb1f677c8b4bcf6 849 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 95 113 1.7E-19 T 28-03-2018 CFK41_RS16685 98716953833a985adcb1f677c8b4bcf6 849 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 1.7E-19 T 28-03-2018 CFK41_RS16685 98716953833a985adcb1f677c8b4bcf6 849 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 627 764 6.2E-19 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CFK41_RS16685 98716953833a985adcb1f677c8b4bcf6 849 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 286 1.6E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS16685 98716953833a985adcb1f677c8b4bcf6 849 SUPERFAMILY SSF55124 497 636 2.78E-25 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CFK41_RS16685 98716953833a985adcb1f677c8b4bcf6 849 Gene3D G3DSA:3.50.50.60 1 107 6.6E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS05990 4584014e882d67897d823e1ca23ba25a 253 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 165 176 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CFK41_RS05990 4584014e882d67897d823e1ca23ba25a 253 Pfam PF13183 4Fe-4S dicluster domain 163 235 3.4E-12 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CFK41_RS05990 4584014e882d67897d823e1ca23ba25a 253 SUPERFAMILY SSF46548 124 248 3.66E-32 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CFK41_RS05990 4584014e882d67897d823e1ca23ba25a 253 Gene3D G3DSA:3.10.20.30 11 123 1.2E-37 T 28-03-2018 IPR012675 Beta-grasp domain CFK41_RS05990 4584014e882d67897d823e1ca23ba25a 253 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 23 128 1.6E-35 T 28-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CFK41_RS05990 4584014e882d67897d823e1ca23ba25a 253 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 26 245 6.6E-79 T 28-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CFK41_RS05990 4584014e882d67897d823e1ca23ba25a 253 Gene3D G3DSA:1.10.1060.10 124 252 3.4E-27 T 28-03-2018 CFK41_RS05990 4584014e882d67897d823e1ca23ba25a 253 SUPERFAMILY SSF54292 20 123 6.46E-28 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CFK41_RS03520 817ea0bd4f92cbd78942824adbfdc6bc 199 SUPERFAMILY SSF53271 18 197 5.38E-31 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CFK41_RS03520 817ea0bd4f92cbd78942824adbfdc6bc 199 Gene3D G3DSA:3.40.50.2020 13 199 3.6E-26 T 28-03-2018 CFK41_RS03520 817ea0bd4f92cbd78942824adbfdc6bc 199 Pfam PF00156 Phosphoribosyl transferase domain 108 176 1.8E-8 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CFK41_RS03520 817ea0bd4f92cbd78942824adbfdc6bc 199 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 199 22.933 T 28-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CFK41_RS15190 00f340aad8e7a9836cb70069dfc3eefe 106 Pfam PF12986 Domain of unknown function (DUF3870) 6 98 1.2E-30 T 28-03-2018 IPR024617 Domain of unknown function DUF3870 CFK41_RS13770 9fc8729a80f5104e7203a8040697eda9 298 Pfam PF01163 RIO1 family 113 279 5.8E-29 T 28-03-2018 CFK41_RS13770 9fc8729a80f5104e7203a8040697eda9 298 Gene3D G3DSA:3.30.200.20 57 178 7.3E-19 T 28-03-2018 CFK41_RS13770 9fc8729a80f5104e7203a8040697eda9 298 SMART SM00090 25 294 8.1E-9 T 28-03-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|Reactome: R-HSA-6791226 CFK41_RS13770 9fc8729a80f5104e7203a8040697eda9 298 SUPERFAMILY SSF56112 133 272 5.88E-12 T 28-03-2018 IPR011009 Protein kinase-like domain CFK41_RS13770 9fc8729a80f5104e7203a8040697eda9 298 Gene3D G3DSA:1.10.510.10 179 298 2.6E-5 T 28-03-2018 CFK41_RS09235 0bb4600dbbc09f7c603a69f1378c13e6 371 Pfam PF01933 Uncharacterised protein family UPF0052 35 294 9.8E-68 T 28-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 CFK41_RS09235 0bb4600dbbc09f7c603a69f1378c13e6 371 Hamap MF_00973 Gluconeogenesis factor. 31 338 30.173 T 28-03-2018 IPR010119 Gluconeogenesis factor CFK41_RS09235 0bb4600dbbc09f7c603a69f1378c13e6 371 SUPERFAMILY SSF142338 32 332 3.66E-80 T 28-03-2018 CFK41_RS09235 0bb4600dbbc09f7c603a69f1378c13e6 371 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 35 298 4.1E-79 T 28-03-2018 IPR010119 Gluconeogenesis factor CFK41_RS09235 0bb4600dbbc09f7c603a69f1378c13e6 371 Gene3D G3DSA:3.40.50.10680 115 341 1.8E-48 T 28-03-2018 CFK41_RS11340 10e24c14f86866c9308783e39f683d22 450 Gene3D G3DSA:1.10.230.10 285 382 1.2E-32 T 28-03-2018 IPR016143 Citrate synthase-like, small alpha subdomain CFK41_RS11340 10e24c14f86866c9308783e39f683d22 450 PRINTS PR00143 Citrate synthase signature 243 271 1.3E-52 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CFK41_RS11340 10e24c14f86866c9308783e39f683d22 450 PRINTS PR00143 Citrate synthase signature 382 396 1.3E-52 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CFK41_RS11340 10e24c14f86866c9308783e39f683d22 450 PRINTS PR00143 Citrate synthase signature 299 319 1.3E-52 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CFK41_RS11340 10e24c14f86866c9308783e39f683d22 450 PRINTS PR00143 Citrate synthase signature 167 180 1.3E-52 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CFK41_RS11340 10e24c14f86866c9308783e39f683d22 450 PRINTS PR00143 Citrate synthase signature 221 236 1.3E-52 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CFK41_RS11340 10e24c14f86866c9308783e39f683d22 450 PRINTS PR00143 Citrate synthase signature 362 378 1.3E-52 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CFK41_RS11340 10e24c14f86866c9308783e39f683d22 450 SUPERFAMILY SSF48256 10 431 2.75E-151 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CFK41_RS11340 10e24c14f86866c9308783e39f683d22 450 Gene3D G3DSA:1.10.580.10 34 284 2.9E-88 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CFK41_RS11340 10e24c14f86866c9308783e39f683d22 450 PIRSF PIRSF001369 39 432 1.4E-154 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type CFK41_RS11340 10e24c14f86866c9308783e39f683d22 450 ProSitePatterns PS00480 Citrate synthase signature. 306 318 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CFK41_RS11340 10e24c14f86866c9308783e39f683d22 450 Pfam PF00285 Citrate synthase, C-terminal domain 48 414 3.8E-130 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CFK41_RS11340 10e24c14f86866c9308783e39f683d22 450 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 15 424 8.1E-174 T 28-03-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 CFK41_RS04410 1ed37c287e96b303714107db13e60662 435 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 114 429 4.1E-69 T 28-03-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 CFK41_RS04410 1ed37c287e96b303714107db13e60662 435 Gene3D G3DSA:3.60.120.10 23 431 8.3E-90 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CFK41_RS04410 1ed37c287e96b303714107db13e60662 435 Pfam PF00425 chorismate binding enzyme 172 421 1.7E-64 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CFK41_RS04410 1ed37c287e96b303714107db13e60662 435 SUPERFAMILY SSF56322 46 429 1.05E-83 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CFK41_RS12090 b14373c5046864939b6c9d7810bffb62 596 Gene3D G3DSA:1.10.10.10 539 593 5.9E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS12090 b14373c5046864939b6c9d7810bffb62 596 Gene3D G3DSA:2.40.30.10 174 279 7.8E-17 T 28-03-2018 CFK41_RS12090 b14373c5046864939b6c9d7810bffb62 596 SUPERFAMILY SSF50447 176 267 5.41E-14 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CFK41_RS12090 b14373c5046864939b6c9d7810bffb62 596 SUPERFAMILY SSF52540 4 194 7.22E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS12090 b14373c5046864939b6c9d7810bffb62 596 Gene3D G3DSA:2.40.30.10 286 337 7.9E-4 T 28-03-2018 CFK41_RS12090 b14373c5046864939b6c9d7810bffb62 596 Gene3D G3DSA:3.40.50.300 2 172 1.7E-25 T 28-03-2018 CFK41_RS12090 b14373c5046864939b6c9d7810bffb62 596 Pfam PF09107 Elongation factor SelB, winged helix 548 591 1.5E-14 T 28-03-2018 IPR015191 Translation elongation factor SelB, winged helix, type 3 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 CFK41_RS12090 b14373c5046864939b6c9d7810bffb62 596 SUPERFAMILY SSF46785 546 589 2.52E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS12090 b14373c5046864939b6c9d7810bffb62 596 Pfam PF00009 Elongation factor Tu GTP binding domain 6 163 8.6E-20 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS00930 7e29f2fa056d634d5b6f49d5e48545b3 292 Gene3D G3DSA:1.10.1790.10 169 278 6.4E-17 T 28-03-2018 IPR011608 PRD domain GO:0006355 CFK41_RS00930 7e29f2fa056d634d5b6f49d5e48545b3 292 SUPERFAMILY SSF50151 1 53 1.57E-13 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CFK41_RS00930 7e29f2fa056d634d5b6f49d5e48545b3 292 SUPERFAMILY SSF63520 90 163 9.55E-14 T 28-03-2018 IPR011608 PRD domain GO:0006355 CFK41_RS00930 7e29f2fa056d634d5b6f49d5e48545b3 292 Pfam PF00874 PRD domain 181 273 4.5E-12 T 28-03-2018 IPR011608 PRD domain GO:0006355 CFK41_RS00930 7e29f2fa056d634d5b6f49d5e48545b3 292 Pfam PF00874 PRD domain 94 163 1.4E-11 T 28-03-2018 IPR011608 PRD domain GO:0006355 CFK41_RS00930 7e29f2fa056d634d5b6f49d5e48545b3 292 SMART SM01061 1 59 3.1E-22 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CFK41_RS00930 7e29f2fa056d634d5b6f49d5e48545b3 292 Gene3D G3DSA:1.10.1790.10 66 164 5.3E-13 T 28-03-2018 IPR011608 PRD domain GO:0006355 CFK41_RS00930 7e29f2fa056d634d5b6f49d5e48545b3 292 SUPERFAMILY SSF63520 172 273 1.09E-19 T 28-03-2018 IPR011608 PRD domain GO:0006355 CFK41_RS00930 7e29f2fa056d634d5b6f49d5e48545b3 292 Gene3D G3DSA:2.30.24.10 1 65 1.6E-20 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CFK41_RS00930 7e29f2fa056d634d5b6f49d5e48545b3 292 Pfam PF03123 CAT RNA binding domain 1 53 4.1E-18 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CFK41_RS11175 4c27dd1d2d2d95b907b30c1a22e04411 560 SUPERFAMILY SSF52540 8 241 1.89E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11175 4c27dd1d2d2d95b907b30c1a22e04411 560 Pfam PF12848 ABC transporter 229 304 1.1E-13 T 28-03-2018 IPR032781 ABC-transporter extension domain CFK41_RS11175 4c27dd1d2d2d95b907b30c1a22e04411 560 Gene3D G3DSA:3.40.50.300 6 288 6.9E-54 T 28-03-2018 CFK41_RS11175 4c27dd1d2d2d95b907b30c1a22e04411 560 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS11175 4c27dd1d2d2d95b907b30c1a22e04411 560 SMART SM00382 30 242 1.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS11175 4c27dd1d2d2d95b907b30c1a22e04411 560 SMART SM00382 348 522 1.1E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS11175 4c27dd1d2d2d95b907b30c1a22e04411 560 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 3 557 2.9E-274 T 28-03-2018 IPR022374 ABC transporter, ATP-binding protein, ChvD CFK41_RS11175 4c27dd1d2d2d95b907b30c1a22e04411 560 SUPERFAMILY SSF52540 309 509 1.11E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11175 4c27dd1d2d2d95b907b30c1a22e04411 560 Pfam PF00005 ABC transporter 21 190 2.8E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS11175 4c27dd1d2d2d95b907b30c1a22e04411 560 Pfam PF00005 ABC transporter 340 473 1.7E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS11175 4c27dd1d2d2d95b907b30c1a22e04411 560 Gene3D G3DSA:3.40.50.300 289 544 5.6E-49 T 28-03-2018 CFK41_RS11175 4c27dd1d2d2d95b907b30c1a22e04411 560 ProSitePatterns PS00211 ABC transporters family signature. 445 459 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS09970 2e3b0f4ab20ff106bc4830bc315d0ff4 197 SUPERFAMILY SSF53098 4 159 4.05E-40 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CFK41_RS09970 2e3b0f4ab20ff106bc4830bc315d0ff4 197 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 117 152 - T 28-03-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 CFK41_RS09970 2e3b0f4ab20ff106bc4830bc315d0ff4 197 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 6 154 6.1E-48 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CFK41_RS09970 2e3b0f4ab20ff106bc4830bc315d0ff4 197 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 4 158 41.062 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CFK41_RS09970 2e3b0f4ab20ff106bc4830bc315d0ff4 197 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 6 155 1.2E-31 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CFK41_RS09970 2e3b0f4ab20ff106bc4830bc315d0ff4 197 Gene3D G3DSA:3.30.420.10 4 160 4.0E-42 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CFK41_RS09970 2e3b0f4ab20ff106bc4830bc315d0ff4 197 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 7 20 3.5E-33 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CFK41_RS09970 2e3b0f4ab20ff106bc4830bc315d0ff4 197 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 111 130 3.5E-33 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CFK41_RS09970 2e3b0f4ab20ff106bc4830bc315d0ff4 197 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 87 103 3.5E-33 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CFK41_RS09970 2e3b0f4ab20ff106bc4830bc315d0ff4 197 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 65 81 3.5E-33 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CFK41_RS09970 2e3b0f4ab20ff106bc4830bc315d0ff4 197 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 143 155 3.5E-33 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CFK41_RS06435 baa977d3778f3dafd17194e757190957 233 Gene3D G3DSA:1.10.10.10 141 231 2.9E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS06435 baa977d3778f3dafd17194e757190957 233 SUPERFAMILY SSF52172 12 147 2.85E-32 T 28-03-2018 IPR011006 CheY-like superfamily CFK41_RS06435 baa977d3778f3dafd17194e757190957 233 Gene3D G3DSA:3.40.50.2300 12 140 2.3E-33 T 28-03-2018 CFK41_RS06435 baa977d3778f3dafd17194e757190957 233 ProSitePatterns PS00622 LuxR-type HTH domain signature. 182 209 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS06435 baa977d3778f3dafd17194e757190957 233 Pfam PF00196 Bacterial regulatory proteins, luxR family 167 222 1.1E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS06435 baa977d3778f3dafd17194e757190957 233 SMART SM00421 165 222 8.5E-27 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS06435 baa977d3778f3dafd17194e757190957 233 SUPERFAMILY SSF46894 150 228 8.84E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CFK41_RS06435 baa977d3778f3dafd17194e757190957 233 SMART SM00448 13 129 3.8E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS06435 baa977d3778f3dafd17194e757190957 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 182 1.7E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS06435 baa977d3778f3dafd17194e757190957 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 198 210 1.7E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS06435 baa977d3778f3dafd17194e757190957 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 198 1.7E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS06435 baa977d3778f3dafd17194e757190957 233 Pfam PF00072 Response regulator receiver domain 15 129 4.5E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS04370 3c98c2fc0973b19d716f15f4cd1f86ba 298 PIRSF PIRSF005355 1 298 1.2E-80 T 28-03-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 CFK41_RS04370 3c98c2fc0973b19d716f15f4cd1f86ba 298 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 12 294 8.7E-80 T 28-03-2018 CFK41_RS04370 3c98c2fc0973b19d716f15f4cd1f86ba 298 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 3 296 21.928 T 28-03-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CFK41_RS04370 3c98c2fc0973b19d716f15f4cd1f86ba 298 Pfam PF01040 UbiA prenyltransferase family 22 259 3.0E-30 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CFK41_RS05490 667c95950ad4574cd457811aa29a6b97 697 SUPERFAMILY SSF55804 4 145 7.06E-32 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CFK41_RS05490 667c95950ad4574cd457811aa29a6b97 697 Gene3D G3DSA:3.40.930.10 1 146 1.5E-30 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CFK41_RS05490 667c95950ad4574cd457811aa29a6b97 697 Gene3D G3DSA:3.40.50.2300 199 297 5.5E-35 T 28-03-2018 CFK41_RS05490 667c95950ad4574cd457811aa29a6b97 697 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 202 290 3.6E-16 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CFK41_RS05490 667c95950ad4574cd457811aa29a6b97 697 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 144 4.3E-28 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CFK41_RS05490 667c95950ad4574cd457811aa29a6b97 697 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 202 283 3.6E-27 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CFK41_RS05490 667c95950ad4574cd457811aa29a6b97 697 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 401 686 8.1E-87 T 28-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 CFK41_RS05490 667c95950ad4574cd457811aa29a6b97 697 SUPERFAMILY SSF52794 200 295 1.92E-29 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CFK41_RS07630 941388a4533aebea2ab91494dc5fee98 116 SUPERFAMILY SSF51182 9 101 1.49E-13 T 28-03-2018 IPR011051 RmlC-like cupin domain CFK41_RS07630 941388a4533aebea2ab91494dc5fee98 116 Gene3D G3DSA:2.60.120.10 5 115 6.9E-14 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CFK41_RS07630 941388a4533aebea2ab91494dc5fee98 116 Pfam PF07883 Cupin domain 33 90 8.4E-8 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CFK41_RS14525 f54b03f460afdb902d499f352ee6445f 282 Pfam PF13560 Helix-turn-helix domain 8 87 1.2E-16 T 28-03-2018 CFK41_RS14525 f54b03f460afdb902d499f352ee6445f 282 SUPERFAMILY SSF47413 30 83 9.6E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS14525 f54b03f460afdb902d499f352ee6445f 282 SMART SM00530 12 84 1.2E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CFK41_RS14525 f54b03f460afdb902d499f352ee6445f 282 Gene3D G3DSA:1.10.260.40 1 98 6.6E-15 T 28-03-2018 CFK41_RS11500 5f49f0b6407d736c98bb1e43f4086cc9 502 SUPERFAMILY SSF53623 129 343 4.84E-46 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CFK41_RS11500 5f49f0b6407d736c98bb1e43f4086cc9 502 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 24 495 3.3E-114 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CFK41_RS11500 5f49f0b6407d736c98bb1e43f4086cc9 502 Gene3D G3DSA:3.90.190.20 349 494 1.1E-35 T 28-03-2018 CFK41_RS11500 5f49f0b6407d736c98bb1e43f4086cc9 502 Gene3D G3DSA:3.40.50.720 12 117 4.7E-20 T 28-03-2018 CFK41_RS11500 5f49f0b6407d736c98bb1e43f4086cc9 502 Pfam PF08245 Mur ligase middle domain 136 257 5.2E-23 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CFK41_RS11500 5f49f0b6407d736c98bb1e43f4086cc9 502 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 134 157 - T 28-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 CFK41_RS11500 5f49f0b6407d736c98bb1e43f4086cc9 502 Gene3D G3DSA:3.40.1190.10 119 348 3.3E-49 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CFK41_RS11500 5f49f0b6407d736c98bb1e43f4086cc9 502 Pfam PF02875 Mur ligase family, glutamate ligase domain 348 413 2.4E-7 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CFK41_RS11500 5f49f0b6407d736c98bb1e43f4086cc9 502 SUPERFAMILY SSF53244 348 497 1.65E-36 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CFK41_RS11500 5f49f0b6407d736c98bb1e43f4086cc9 502 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 23 497 32.197 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CFK41_RS11500 5f49f0b6407d736c98bb1e43f4086cc9 502 SUPERFAMILY SSF51984 19 117 6.41E-16 T 28-03-2018 CFK41_RS10900 f16c0bb65c25499e705b553141845dde 157 Gene3D G3DSA:3.40.630.30 1 153 2.4E-24 T 28-03-2018 CFK41_RS10900 f16c0bb65c25499e705b553141845dde 157 Pfam PF00583 Acetyltransferase (GNAT) family 35 146 6.0E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS10900 f16c0bb65c25499e705b553141845dde 157 SUPERFAMILY SSF55729 10 152 2.74E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS13085 c8c8c46d0245cb15250dd4ffc30e2ee2 581 SMART SM00382 36 235 4.6E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS13085 c8c8c46d0245cb15250dd4ffc30e2ee2 581 SMART SM00382 338 523 4.0E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS13085 c8c8c46d0245cb15250dd4ffc30e2ee2 581 SUPERFAMILY SSF52540 4 241 4.11E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS13085 c8c8c46d0245cb15250dd4ffc30e2ee2 581 Pfam PF00005 ABC transporter 27 177 2.1E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS13085 c8c8c46d0245cb15250dd4ffc30e2ee2 581 Pfam PF00005 ABC transporter 330 475 3.6E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS13085 c8c8c46d0245cb15250dd4ffc30e2ee2 581 SUPERFAMILY SSF52540 324 542 1.25E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS13085 c8c8c46d0245cb15250dd4ffc30e2ee2 581 Gene3D G3DSA:3.40.50.300 6 271 5.7E-60 T 28-03-2018 CFK41_RS13085 c8c8c46d0245cb15250dd4ffc30e2ee2 581 ProSitePatterns PS00211 ABC transporters family signature. 447 461 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS13085 c8c8c46d0245cb15250dd4ffc30e2ee2 581 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS13085 c8c8c46d0245cb15250dd4ffc30e2ee2 581 Pfam PF12558 ATP-binding cassette cobalt transporter 242 292 9.7E-8 T 28-03-2018 IPR022216 ABC cobalt transporter GO:0016820 CFK41_RS13085 c8c8c46d0245cb15250dd4ffc30e2ee2 581 Gene3D G3DSA:3.40.50.300 305 551 1.2E-52 T 28-03-2018 CFK41_RS09250 32351b2c40f2fbe46c16bde4ff7a51f8 958 ProSitePatterns PS00211 ABC transporters family signature. 834 848 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS09250 32351b2c40f2fbe46c16bde4ff7a51f8 958 Gene3D G3DSA:3.40.50.300 37 88 0.009 T 28-03-2018 CFK41_RS09250 32351b2c40f2fbe46c16bde4ff7a51f8 958 SUPERFAMILY SSF52540 9 205 5.2E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS09250 32351b2c40f2fbe46c16bde4ff7a51f8 958 SUPERFAMILY SSF52540 435 567 5.2E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS09250 32351b2c40f2fbe46c16bde4ff7a51f8 958 Gene3D G3DSA:1.10.8.280 290 410 9.3E-38 T 28-03-2018 CFK41_RS09250 32351b2c40f2fbe46c16bde4ff7a51f8 958 SUPERFAMILY SSF52540 627 915 7.17E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS09250 32351b2c40f2fbe46c16bde4ff7a51f8 958 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 929 0.0 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CFK41_RS09250 32351b2c40f2fbe46c16bde4ff7a51f8 958 Gene3D G3DSA:3.40.50.300 425 619 8.2E-23 T 28-03-2018 CFK41_RS09250 32351b2c40f2fbe46c16bde4ff7a51f8 958 Gene3D G3DSA:3.30.190.20 128 248 2.6E-40 T 28-03-2018 CFK41_RS09250 32351b2c40f2fbe46c16bde4ff7a51f8 958 Gene3D G3DSA:3.40.50.300 620 946 1.8E-52 T 28-03-2018 CFK41_RS09250 32351b2c40f2fbe46c16bde4ff7a51f8 958 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 944 22.589 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CFK41_RS09250 32351b2c40f2fbe46c16bde4ff7a51f8 958 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS09250 32351b2c40f2fbe46c16bde4ff7a51f8 958 Gene3D G3DSA:3.40.50.300 9 36 0.024 T 28-03-2018 CFK41_RS09250 32351b2c40f2fbe46c16bde4ff7a51f8 958 Pfam PF00005 ABC transporter 634 864 3.4E-7 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS02995 cb5cab37890ef1baeaca4f3111893adf 526 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CFK41_RS02995 cb5cab37890ef1baeaca4f3111893adf 526 SUPERFAMILY SSF56112 10 270 3.1E-75 T 28-03-2018 IPR011009 Protein kinase-like domain CFK41_RS02995 cb5cab37890ef1baeaca4f3111893adf 526 Pfam PF00069 Protein kinase domain 13 265 2.0E-49 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CFK41_RS02995 cb5cab37890ef1baeaca4f3111893adf 526 Gene3D G3DSA:3.30.200.20 5 95 2.7E-20 T 28-03-2018 CFK41_RS02995 cb5cab37890ef1baeaca4f3111893adf 526 Gene3D G3DSA:1.10.510.10 96 323 1.1E-50 T 28-03-2018 CFK41_RS02995 cb5cab37890ef1baeaca4f3111893adf 526 SMART SM00220 13 272 3.8E-62 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CFK41_RS05255 d2f24e3ae81dac484789111ab6a8b924 206 Pfam PF01545 Cation efflux family 18 183 3.2E-11 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CFK41_RS05255 d2f24e3ae81dac484789111ab6a8b924 206 SUPERFAMILY SSF161111 9 187 3.01E-28 T 28-03-2018 CFK41_RS05255 d2f24e3ae81dac484789111ab6a8b924 206 Gene3D G3DSA:1.20.1510.10 10 188 8.6E-16 T 28-03-2018 CFK41_RS04535 68bd6da9af3565baf441dace51ab5097 156 PIRSF PIRSF002122 3 156 7.9E-56 T 28-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 CFK41_RS04535 68bd6da9af3565baf441dace51ab5097 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 34.387 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CFK41_RS04535 68bd6da9af3565baf441dace51ab5097 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 7.2E-64 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CFK41_RS04535 68bd6da9af3565baf441dace51ab5097 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 28-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04535 68bd6da9af3565baf441dace51ab5097 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 1.6E-60 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CFK41_RS04535 68bd6da9af3565baf441dace51ab5097 156 Gene3D G3DSA:1.10.455.10 6 156 1.6E-55 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CFK41_RS04535 68bd6da9af3565baf441dace51ab5097 156 SUPERFAMILY SSF47973 1 149 4.84E-57 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CFK41_RS06605 0579d96bb802e76b66c5bdc9903ebfa7 462 Gene3D G3DSA:3.20.140.10 1 364 3.3E-88 T 28-03-2018 CFK41_RS06605 0579d96bb802e76b66c5bdc9903ebfa7 462 PIRSF PIRSF000484 2 403 2.5E-88 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CFK41_RS06605 0579d96bb802e76b66c5bdc9903ebfa7 462 SUPERFAMILY SSF51690 137 437 1.05E-73 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CFK41_RS06605 0579d96bb802e76b66c5bdc9903ebfa7 462 SUPERFAMILY SSF54675 2 135 4.71E-43 T 28-03-2018 CFK41_RS06605 0579d96bb802e76b66c5bdc9903ebfa7 462 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 7 414 2.4E-119 T 28-03-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 CFK41_RS08300 7c166d0ef1e0ba8fe5682273c0f98f34 656 SMART SM00400 38 92 2.4E-34 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CFK41_RS08300 7c166d0ef1e0ba8fe5682273c0f98f34 656 Pfam PF01807 CHC2 zinc finger 8 103 1.4E-30 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CFK41_RS08300 7c166d0ef1e0ba8fe5682273c0f98f34 656 SUPERFAMILY SSF56731 119 445 4.71E-93 T 28-03-2018 CFK41_RS08300 7c166d0ef1e0ba8fe5682273c0f98f34 656 Gene3D G3DSA:3.40.1360.10 245 387 1.8E-30 T 28-03-2018 CFK41_RS08300 7c166d0ef1e0ba8fe5682273c0f98f34 656 Pfam PF13662 Toprim domain 264 348 7.7E-15 T 28-03-2018 IPR006171 TOPRIM domain CFK41_RS08300 7c166d0ef1e0ba8fe5682273c0f98f34 656 SUPERFAMILY SSF57783 6 103 1.24E-31 T 28-03-2018 CFK41_RS08300 7c166d0ef1e0ba8fe5682273c0f98f34 656 Pfam PF08275 DNA primase catalytic core, N-terminal domain 129 255 8.3E-38 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CFK41_RS08300 7c166d0ef1e0ba8fe5682273c0f98f34 656 SMART SM00493 263 353 2.7E-9 T 28-03-2018 IPR006171 TOPRIM domain CFK41_RS08300 7c166d0ef1e0ba8fe5682273c0f98f34 656 PIRSF PIRSF002811 4 649 8.9E-144 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CFK41_RS08300 7c166d0ef1e0ba8fe5682273c0f98f34 656 Gene3D G3DSA:3.90.980.10 114 244 1.3E-40 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CFK41_RS08300 7c166d0ef1e0ba8fe5682273c0f98f34 656 Pfam PF08278 DNA primase DnaG DnaB-binding 509 636 3.6E-8 T 28-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 CFK41_RS08300 7c166d0ef1e0ba8fe5682273c0f98f34 656 Gene3D G3DSA:1.10.860.10 489 643 1.3E-10 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CFK41_RS08300 7c166d0ef1e0ba8fe5682273c0f98f34 656 Pfam PF10410 DnaB-helicase binding domain of primase 389 443 1.0E-16 T 28-03-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 CFK41_RS08300 7c166d0ef1e0ba8fe5682273c0f98f34 656 Hamap MF_00974 DNA primase [dnaG]. 5 643 25.702 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CFK41_RS08300 7c166d0ef1e0ba8fe5682273c0f98f34 656 TIGRFAM TIGR01391 dnaG: DNA primase 9 436 4.4E-109 T 28-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 CFK41_RS08300 7c166d0ef1e0ba8fe5682273c0f98f34 656 Gene3D G3DSA:1.20.50.20 388 441 1.4E-19 T 28-03-2018 CFK41_RS08300 7c166d0ef1e0ba8fe5682273c0f98f34 656 Gene3D G3DSA:3.90.580.10 2 105 5.4E-31 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CFK41_RS07450 051c0be1f85b1a01edd4c1f5d7ffcf7e 278 Pfam PF12833 Helix-turn-helix domain 190 267 1.8E-16 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CFK41_RS07450 051c0be1f85b1a01edd4c1f5d7ffcf7e 278 SUPERFAMILY SSF46689 231 268 7.17E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS07450 051c0be1f85b1a01edd4c1f5d7ffcf7e 278 SMART SM00342 179 266 2.0E-9 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CFK41_RS07450 051c0be1f85b1a01edd4c1f5d7ffcf7e 278 Gene3D G3DSA:1.10.10.60 220 272 9.7E-9 T 28-03-2018 CFK41_RS07450 051c0be1f85b1a01edd4c1f5d7ffcf7e 278 Gene3D G3DSA:1.10.10.60 116 219 0.0029 T 28-03-2018 CFK41_RS08830 56459eee1f6df5fd1522ff33e09e331b 264 SMART SM00382 30 231 1.4E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS08830 56459eee1f6df5fd1522ff33e09e331b 264 SUPERFAMILY SSF52540 8 242 4.57E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS08830 56459eee1f6df5fd1522ff33e09e331b 264 Pfam PF00005 ABC transporter 21 172 3.1E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS08830 56459eee1f6df5fd1522ff33e09e331b 264 Gene3D G3DSA:3.40.50.300 2 255 2.7E-47 T 28-03-2018 CFK41_RS13215 28621ee2f8c2e9e54b81da725dd71a54 393 Gene3D G3DSA:3.30.420.40 95 231 2.6E-25 T 28-03-2018 CFK41_RS13215 28621ee2f8c2e9e54b81da725dd71a54 393 Gene3D G3DSA:1.10.10.10 26 90 5.1E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS13215 28621ee2f8c2e9e54b81da725dd71a54 393 SUPERFAMILY SSF46785 28 87 3.29E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS13215 28621ee2f8c2e9e54b81da725dd71a54 393 Pfam PF00480 ROK family 98 340 4.1E-25 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CFK41_RS13215 28621ee2f8c2e9e54b81da725dd71a54 393 SUPERFAMILY SSF53067 96 387 3.08E-29 T 28-03-2018 CFK41_RS13215 28621ee2f8c2e9e54b81da725dd71a54 393 Gene3D G3DSA:3.30.420.40 232 368 4.2E-23 T 28-03-2018 CFK41_RS00255 d6802802bd82148371597fc02c551c94 178 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 83 9.2E-6 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CFK41_RS00255 d6802802bd82148371597fc02c551c94 178 Gene3D G3DSA:3.10.450.50 124 167 7.7E-4 T 28-03-2018 CFK41_RS00255 d6802802bd82148371597fc02c551c94 178 Gene3D G3DSA:3.90.180.10 1 123 2.3E-24 T 28-03-2018 CFK41_RS00255 d6802802bd82148371597fc02c551c94 178 SUPERFAMILY SSF50129 3 124 4.87E-23 T 28-03-2018 IPR011032 GroES-like CFK41_RS16090 f1a840bd8ec67b5bdc9270fe9c825afa 329 Gene3D G3DSA:3.40.190.10 76 184 1.1E-18 T 28-03-2018 CFK41_RS16090 f1a840bd8ec67b5bdc9270fe9c825afa 329 Gene3D G3DSA:3.40.190.10 185 268 9.8E-12 T 28-03-2018 CFK41_RS16090 f1a840bd8ec67b5bdc9270fe9c825afa 329 SMART SM00062 83 315 5.8E-20 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CFK41_RS16090 f1a840bd8ec67b5bdc9270fe9c825afa 329 SUPERFAMILY SSF53850 74 312 7.97E-39 T 28-03-2018 CFK41_RS16090 f1a840bd8ec67b5bdc9270fe9c825afa 329 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 86 311 5.8E-36 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CFK41_RS07425 41f809fcf151a035631d1c34a4146796 184 Gene3D G3DSA:3.40.50.150 1 182 1.2E-28 T 28-03-2018 CFK41_RS07425 41f809fcf151a035631d1c34a4146796 184 SUPERFAMILY SSF53335 2 179 7.19E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS07425 41f809fcf151a035631d1c34a4146796 184 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 3 180 1.1E-36 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CFK41_RS07425 41f809fcf151a035631d1c34a4146796 184 Pfam PF03602 Conserved hypothetical protein 95 3 180 6.1E-43 T 28-03-2018 CFK41_RS07425 41f809fcf151a035631d1c34a4146796 184 PIRSF PIRSF004553 1 182 5.5E-43 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CFK41_RS07550 100a8db0cc1ab0c249bf0bcc71c0836d 201 Pfam PF01467 Cytidylyltransferase-like 10 170 6.5E-30 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CFK41_RS07550 100a8db0cc1ab0c249bf0bcc71c0836d 201 Gene3D G3DSA:3.40.50.620 1 196 1.3E-51 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS07550 100a8db0cc1ab0c249bf0bcc71c0836d 201 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 10 195 2.9E-54 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CFK41_RS07550 100a8db0cc1ab0c249bf0bcc71c0836d 201 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 6 196 29.776 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CFK41_RS07550 100a8db0cc1ab0c249bf0bcc71c0836d 201 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 8 72 6.4E-10 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CFK41_RS07550 100a8db0cc1ab0c249bf0bcc71c0836d 201 SUPERFAMILY SSF52374 6 197 6.88E-51 T 28-03-2018 CFK41_RS05640 80cb718cbd1b42d4a8f38e30f289e3da 380 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 19 378 50.428 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CFK41_RS05640 80cb718cbd1b42d4a8f38e30f289e3da 380 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 241 250 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CFK41_RS05640 80cb718cbd1b42d4a8f38e30f289e3da 380 Gene3D G3DSA:3.40.640.10 53 303 1.1E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS05640 80cb718cbd1b42d4a8f38e30f289e3da 380 SUPERFAMILY SSF53383 40 377 1.24E-68 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS05640 80cb718cbd1b42d4a8f38e30f289e3da 380 Pfam PF00155 Aminotransferase class I and II 41 369 3.4E-52 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CFK41_RS05640 80cb718cbd1b42d4a8f38e30f289e3da 380 Gene3D G3DSA:3.90.1150.10 304 377 1.8E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS07000 8bff93aa4c3241366788d91139384444 327 SMART SM00354 7 77 1.6E-25 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS07000 8bff93aa4c3241366788d91139384444 327 Gene3D G3DSA:3.40.50.2300 59 173 3.2E-14 T 28-03-2018 CFK41_RS07000 8bff93aa4c3241366788d91139384444 327 Pfam PF00356 Bacterial regulatory proteins, lacI family 9 54 9.9E-18 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS07000 8bff93aa4c3241366788d91139384444 327 Gene3D G3DSA:1.10.260.40 24 58 7.2E-20 T 28-03-2018 CFK41_RS07000 8bff93aa4c3241366788d91139384444 327 SUPERFAMILY SSF47413 7 62 7.13E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS07000 8bff93aa4c3241366788d91139384444 327 SUPERFAMILY SSF53822 67 327 3.53E-27 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS07000 8bff93aa4c3241366788d91139384444 327 Pfam PF13377 Periplasmic binding protein-like domain 224 327 7.4E-20 T 28-03-2018 CFK41_RS07000 8bff93aa4c3241366788d91139384444 327 Gene3D G3DSA:1.10.10.10 1 23 8.8E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS07000 8bff93aa4c3241366788d91139384444 327 Gene3D G3DSA:3.40.50.2300 174 306 2.8E-19 T 28-03-2018 CFK41_RS07000 8bff93aa4c3241366788d91139384444 327 ProSitePatterns PS00356 LacI-type HTH domain signature. 10 28 - T 28-03-2018 CFK41_RS00035 5524442ecc7a01bf0b02ac7c0b509c2d 346 Pfam PF01595 Domain of unknown function DUF21 9 200 1.1E-41 T 28-03-2018 IPR002550 Domain of unknown function DUF21 CFK41_RS00035 5524442ecc7a01bf0b02ac7c0b509c2d 346 SUPERFAMILY SSF54631 209 341 2.15E-19 T 28-03-2018 CFK41_RS00035 5524442ecc7a01bf0b02ac7c0b509c2d 346 Gene3D G3DSA:3.20.20.70 159 346 9.4E-26 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS00035 5524442ecc7a01bf0b02ac7c0b509c2d 346 Pfam PF00571 CBS domain 290 335 1.2E-5 T 28-03-2018 IPR000644 CBS domain CFK41_RS10990 375bac3c092096392153baff5c67234d 445 Gene3D G3DSA:3.30.565.10 319 445 1.8E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS10990 375bac3c092096392153baff5c67234d 445 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 356 404 5.1E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS10990 375bac3c092096392153baff5c67234d 445 SUPERFAMILY SSF55874 339 442 1.92E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS10990 375bac3c092096392153baff5c67234d 445 Pfam PF13796 Putative sensor 39 229 6.4E-31 T 28-03-2018 IPR025828 Putative sensor domain CFK41_RS10990 375bac3c092096392153baff5c67234d 445 Pfam PF07730 Histidine kinase 258 322 4.3E-11 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CFK41_RS10990 375bac3c092096392153baff5c67234d 445 SMART SM00387 355 445 2.1E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS00065 f7529a3040339bd4f097158da4ee5a43 573 Pfam PF00425 chorismate binding enzyme 113 360 3.3E-77 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CFK41_RS00065 f7529a3040339bd4f097158da4ee5a43 573 Gene3D G3DSA:3.60.120.10 20 366 2.0E-101 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CFK41_RS00065 f7529a3040339bd4f097158da4ee5a43 573 Gene3D G3DSA:3.20.10.10 446 569 1.8E-22 T 28-03-2018 CFK41_RS00065 f7529a3040339bd4f097158da4ee5a43 573 SUPERFAMILY SSF56322 41 364 4.45E-96 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CFK41_RS00065 f7529a3040339bd4f097158da4ee5a43 573 Gene3D G3DSA:3.30.470.10 371 445 5.2E-14 T 28-03-2018 CFK41_RS00065 f7529a3040339bd4f097158da4ee5a43 573 PRINTS PR00095 Anthranilate synthase component I signature 204 217 1.2E-11 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CFK41_RS00065 f7529a3040339bd4f097158da4ee5a43 573 PRINTS PR00095 Anthranilate synthase component I signature 218 231 1.2E-11 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CFK41_RS00065 f7529a3040339bd4f097158da4ee5a43 573 PRINTS PR00095 Anthranilate synthase component I signature 298 312 1.2E-11 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CFK41_RS00065 f7529a3040339bd4f097158da4ee5a43 573 Pfam PF01063 Amino-transferase class IV 374 564 3.9E-27 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CFK41_RS00065 f7529a3040339bd4f097158da4ee5a43 573 SUPERFAMILY SSF56752 342 565 2.75E-33 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CFK41_RS11755 dbd706a0d7ffb9c8f9d870baf98969a1 328 Gene3D G3DSA:3.30.300.20 176 253 4.4E-29 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CFK41_RS11755 dbd706a0d7ffb9c8f9d870baf98969a1 328 SUPERFAMILY SSF50249 109 176 9.21E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS11755 dbd706a0d7ffb9c8f9d870baf98969a1 328 SUPERFAMILY SSF54814 256 318 2.96E-16 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CFK41_RS11755 dbd706a0d7ffb9c8f9d870baf98969a1 328 SUPERFAMILY SSF54814 177 255 5.69E-25 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CFK41_RS11755 dbd706a0d7ffb9c8f9d870baf98969a1 328 SUPERFAMILY SSF69705 2 99 7.59E-25 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CFK41_RS11755 dbd706a0d7ffb9c8f9d870baf98969a1 328 Gene3D G3DSA:3.30.1480.10 1 99 4.9E-23 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CFK41_RS11755 dbd706a0d7ffb9c8f9d870baf98969a1 328 Pfam PF08529 NusA N-terminal domain 66 100 5.9E-7 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CFK41_RS11755 dbd706a0d7ffb9c8f9d870baf98969a1 328 Pfam PF08529 NusA N-terminal domain 7 60 4.5E-5 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CFK41_RS11755 dbd706a0d7ffb9c8f9d870baf98969a1 328 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 76 319 2.7E-92 T 28-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 CFK41_RS11755 dbd706a0d7ffb9c8f9d870baf98969a1 328 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 1 326 24.811 T 28-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 CFK41_RS11755 dbd706a0d7ffb9c8f9d870baf98969a1 328 Gene3D G3DSA:2.40.50.140 113 175 8.4E-12 T 28-03-2018 CFK41_RS11755 dbd706a0d7ffb9c8f9d870baf98969a1 328 Gene3D G3DSA:3.30.300.20 255 326 1.4E-15 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CFK41_RS11755 dbd706a0d7ffb9c8f9d870baf98969a1 328 Pfam PF13184 NusA-like KH domain 207 274 1.7E-23 T 28-03-2018 IPR025249 KH domain, NusA-like GO:0003723 CFK41_RS09405 7fa70f8ff14ab78f7d44d3e7ade06d60 745 PRINTS PR00067 Catalase signature 85 108 4.2E-70 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CFK41_RS09405 7fa70f8ff14ab78f7d44d3e7ade06d60 745 PRINTS PR00067 Catalase signature 168 185 4.2E-70 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CFK41_RS09405 7fa70f8ff14ab78f7d44d3e7ade06d60 745 PRINTS PR00067 Catalase signature 147 165 4.2E-70 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CFK41_RS09405 7fa70f8ff14ab78f7d44d3e7ade06d60 745 PRINTS PR00067 Catalase signature 389 415 4.2E-70 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CFK41_RS09405 7fa70f8ff14ab78f7d44d3e7ade06d60 745 PRINTS PR00067 Catalase signature 357 384 4.2E-70 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CFK41_RS09405 7fa70f8ff14ab78f7d44d3e7ade06d60 745 PRINTS PR00067 Catalase signature 187 205 4.2E-70 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CFK41_RS09405 7fa70f8ff14ab78f7d44d3e7ade06d60 745 SUPERFAMILY SSF52317 588 740 7.85E-7 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS09405 7fa70f8ff14ab78f7d44d3e7ade06d60 745 Gene3D G3DSA:3.40.50.880 586 745 3.0E-14 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS09405 7fa70f8ff14ab78f7d44d3e7ade06d60 745 ProSitePatterns PS00438 Catalase proximal active site signature. 108 124 - T 28-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CFK41_RS09405 7fa70f8ff14ab78f7d44d3e7ade06d60 745 Pfam PF00199 Catalase 72 457 5.9E-163 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CFK41_RS09405 7fa70f8ff14ab78f7d44d3e7ade06d60 745 Pfam PF06628 Catalase-related immune-responsive 489 552 2.8E-23 T 28-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CFK41_RS09405 7fa70f8ff14ab78f7d44d3e7ade06d60 745 SMART SM01060 72 460 5.5E-244 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CFK41_RS09405 7fa70f8ff14ab78f7d44d3e7ade06d60 745 PIRSF PIRSF038927 41 745 4.1E-272 T 28-03-2018 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 CFK41_RS09405 7fa70f8ff14ab78f7d44d3e7ade06d60 745 Gene3D G3DSA:2.40.180.10 46 427 4.8E-151 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CFK41_RS09405 7fa70f8ff14ab78f7d44d3e7ade06d60 745 SUPERFAMILY SSF56634 63 561 9.29E-201 T 28-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CFK41_RS09405 7fa70f8ff14ab78f7d44d3e7ade06d60 745 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 402 410 - T 28-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CFK41_RS08710 39a84fa70f926c6d20a5fe685419e28c 285 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 1 285 32.017 T 28-03-2018 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 CFK41_RS08710 39a84fa70f926c6d20a5fe685419e28c 285 SUPERFAMILY SSF53850 1 211 1.52E-59 T 28-03-2018 CFK41_RS08710 39a84fa70f926c6d20a5fe685419e28c 285 Pfam PF01634 ATP phosphoribosyltransferase 49 205 1.1E-42 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CFK41_RS08710 39a84fa70f926c6d20a5fe685419e28c 285 SUPERFAMILY SSF54913 212 284 5.23E-21 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CFK41_RS08710 39a84fa70f926c6d20a5fe685419e28c 285 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 192 284 2.4E-28 T 28-03-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CFK41_RS08710 39a84fa70f926c6d20a5fe685419e28c 285 Gene3D G3DSA:3.40.190.10 113 210 7.7E-17 T 28-03-2018 CFK41_RS08710 39a84fa70f926c6d20a5fe685419e28c 285 Gene3D G3DSA:3.40.190.10 1 112 1.1E-33 T 28-03-2018 CFK41_RS08710 39a84fa70f926c6d20a5fe685419e28c 285 Pfam PF08029 HisG, C-terminal domain 210 281 4.4E-25 T 28-03-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CFK41_RS08710 39a84fa70f926c6d20a5fe685419e28c 285 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 141 162 - T 28-03-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 CFK41_RS08710 39a84fa70f926c6d20a5fe685419e28c 285 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 2 182 2.5E-52 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CFK41_RS08710 39a84fa70f926c6d20a5fe685419e28c 285 Gene3D G3DSA:3.30.70.120 213 277 1.7E-23 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CFK41_RS06770 72615136dd4d356220b0e26a65009ac4 840 Pfam PF01571 Aminomethyltransferase folate-binding domain 432 711 1.3E-64 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal CFK41_RS06770 72615136dd4d356220b0e26a65009ac4 840 Gene3D G3DSA:2.40.30.110 732 824 7.2E-12 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CFK41_RS06770 72615136dd4d356220b0e26a65009ac4 840 Gene3D G3DSA:3.40.50.720 2 43 0.0011 T 28-03-2018 CFK41_RS06770 72615136dd4d356220b0e26a65009ac4 840 SUPERFAMILY SSF103025 425 733 5.81E-79 T 28-03-2018 CFK41_RS06770 72615136dd4d356220b0e26a65009ac4 840 Gene3D G3DSA:3.30.9.10 84 164 4.9E-9 T 28-03-2018 CFK41_RS06770 72615136dd4d356220b0e26a65009ac4 840 SUPERFAMILY SSF101790 764 839 3.92E-10 T 28-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain CFK41_RS06770 72615136dd4d356220b0e26a65009ac4 840 Pfam PF16350 FAD dependent oxidoreductase central domain 375 430 4.8E-17 T 28-03-2018 IPR032503 FAD dependent oxidoreductase, central domain CFK41_RS06770 72615136dd4d356220b0e26a65009ac4 840 Gene3D G3DSA:3.30.1360.120 582 689 5.2E-16 T 28-03-2018 CFK41_RS06770 72615136dd4d356220b0e26a65009ac4 840 Gene3D G3DSA:3.30.1360.120 427 581 1.0E-28 T 28-03-2018 CFK41_RS06770 72615136dd4d356220b0e26a65009ac4 840 Gene3D G3DSA:4.10.1250.10 691 731 1.7E-6 T 28-03-2018 CFK41_RS06770 72615136dd4d356220b0e26a65009ac4 840 Pfam PF01266 FAD dependent oxidoreductase 9 372 3.0E-43 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CFK41_RS06770 72615136dd4d356220b0e26a65009ac4 840 SUPERFAMILY SSF54373 219 334 4.71E-16 T 28-03-2018 CFK41_RS06770 72615136dd4d356220b0e26a65009ac4 840 Gene3D G3DSA:3.30.9.10 165 335 1.7E-29 T 28-03-2018 CFK41_RS06770 72615136dd4d356220b0e26a65009ac4 840 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 719 823 1.4E-11 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CFK41_RS06770 72615136dd4d356220b0e26a65009ac4 840 SUPERFAMILY SSF51905 336 412 3.15E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS06770 72615136dd4d356220b0e26a65009ac4 840 SUPERFAMILY SSF51905 8 219 3.15E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS04375 126788f65416c792c83489f3fe20ec8d 439 Pfam PF00501 AMP-binding enzyme 56 327 1.4E-21 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CFK41_RS04375 126788f65416c792c83489f3fe20ec8d 439 Gene3D G3DSA:3.30.300.30 322 434 1.8E-20 T 28-03-2018 CFK41_RS04375 126788f65416c792c83489f3fe20ec8d 439 SUPERFAMILY SSF56801 41 431 6.54E-56 T 28-03-2018 CFK41_RS04375 126788f65416c792c83489f3fe20ec8d 439 Gene3D G3DSA:2.30.38.10 244 321 1.1E-5 T 28-03-2018 CFK41_RS04375 126788f65416c792c83489f3fe20ec8d 439 Gene3D G3DSA:3.40.50.980 5 66 0.0015 T 28-03-2018 CFK41_RS04375 126788f65416c792c83489f3fe20ec8d 439 Gene3D G3DSA:3.40.50.980 67 243 1.1E-17 T 28-03-2018 CFK41_RS04375 126788f65416c792c83489f3fe20ec8d 439 Pfam PF13193 AMP-binding enzyme C-terminal domain 350 418 1.7E-8 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CFK41_RS04375 126788f65416c792c83489f3fe20ec8d 439 ProSitePatterns PS00455 Putative AMP-binding domain signature. 65 76 - T 28-03-2018 IPR020845 AMP-binding, conserved site CFK41_RS00495 3b115e40bde6e9c06a7478efb6508a97 305 Gene3D G3DSA:3.40.190.10 93 175 1.5E-12 T 28-03-2018 CFK41_RS00495 3b115e40bde6e9c06a7478efb6508a97 305 Gene3D G3DSA:3.40.190.10 176 266 7.4E-17 T 28-03-2018 CFK41_RS00495 3b115e40bde6e9c06a7478efb6508a97 305 Gene3D G3DSA:1.10.10.10 2 92 1.7E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS00495 3b115e40bde6e9c06a7478efb6508a97 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 1.6E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CFK41_RS00495 3b115e40bde6e9c06a7478efb6508a97 305 Pfam PF03466 LysR substrate binding domain 88 290 7.9E-25 T 28-03-2018 IPR005119 LysR, substrate-binding CFK41_RS00495 3b115e40bde6e9c06a7478efb6508a97 305 SUPERFAMILY SSF53850 89 295 9.41E-26 T 28-03-2018 CFK41_RS00495 3b115e40bde6e9c06a7478efb6508a97 305 SUPERFAMILY SSF46785 1 109 2.87E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS07245 2a620e49a8eea9b4c5de16a1ba510771 343 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 184 327 1.7E-63 T 28-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CFK41_RS07245 2a620e49a8eea9b4c5de16a1ba510771 343 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 327 4.5E-131 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CFK41_RS07245 2a620e49a8eea9b4c5de16a1ba510771 343 SUPERFAMILY SSF48179 184 328 9.18E-66 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CFK41_RS07245 2a620e49a8eea9b4c5de16a1ba510771 343 Gene3D G3DSA:1.10.1040.10 64 331 2.5E-114 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CFK41_RS07245 2a620e49a8eea9b4c5de16a1ba510771 343 SUPERFAMILY SSF51735 3 183 8.77E-72 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS07245 2a620e49a8eea9b4c5de16a1ba510771 343 Gene3D G3DSA:3.50.50.60 4 63 0.0029 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS07245 2a620e49a8eea9b4c5de16a1ba510771 343 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 2 329 45.043 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CFK41_RS07245 2a620e49a8eea9b4c5de16a1ba510771 343 PIRSF PIRSF000116 203 332 9.4E-13 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CFK41_RS07245 2a620e49a8eea9b4c5de16a1ba510771 343 PIRSF PIRSF000116 3 208 1.1E-44 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CFK41_RS07245 2a620e49a8eea9b4c5de16a1ba510771 343 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 178 2.3E-75 T 28-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CFK41_RS06955 c029686d61b4bea32e5915ec6ac1346d 455 SUPERFAMILY SSF55021 368 434 1.89E-8 T 28-03-2018 CFK41_RS06955 c029686d61b4bea32e5915ec6ac1346d 455 Gene3D G3DSA:3.30.70.260 365 451 2.2E-15 T 28-03-2018 CFK41_RS06955 c029686d61b4bea32e5915ec6ac1346d 455 Gene3D G3DSA:3.30.360.10 166 320 5.8E-58 T 28-03-2018 CFK41_RS06955 c029686d61b4bea32e5915ec6ac1346d 455 Pfam PF00742 Homoserine dehydrogenase 154 336 2.0E-65 T 28-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CFK41_RS06955 c029686d61b4bea32e5915ec6ac1346d 455 Pfam PF01842 ACT domain 370 401 1.4E-8 T 28-03-2018 IPR002912 ACT domain CFK41_RS06955 c029686d61b4bea32e5915ec6ac1346d 455 SUPERFAMILY SSF55347 154 323 2.09E-50 T 28-03-2018 CFK41_RS06955 c029686d61b4bea32e5915ec6ac1346d 455 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 200 222 - T 28-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CFK41_RS06955 c029686d61b4bea32e5915ec6ac1346d 455 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 29 146 4.6E-23 T 28-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CFK41_RS06955 c029686d61b4bea32e5915ec6ac1346d 455 Gene3D G3DSA:3.40.50.720 19 165 1.1E-23 T 28-03-2018 CFK41_RS06955 c029686d61b4bea32e5915ec6ac1346d 455 PIRSF PIRSF000098 21 455 8.2E-153 T 28-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CFK41_RS06955 c029686d61b4bea32e5915ec6ac1346d 455 SUPERFAMILY SSF51735 22 175 6.85E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS14545 3b32e0bf0d2df7eaef0014c02607b91a 427 Gene3D G3DSA:1.20.1250.20 206 410 6.5E-21 T 28-03-2018 CFK41_RS14545 3b32e0bf0d2df7eaef0014c02607b91a 427 Gene3D G3DSA:1.20.1250.20 1 196 6.0E-40 T 28-03-2018 CFK41_RS14545 3b32e0bf0d2df7eaef0014c02607b91a 427 SUPERFAMILY SSF103473 2 409 1.44E-78 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS14545 3b32e0bf0d2df7eaef0014c02607b91a 427 Pfam PF07690 Major Facilitator Superfamily 10 371 2.0E-61 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS09100 031a52e95562b684b676046bbd763e50 200 SMART SM00347 68 170 4.5E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS09100 031a52e95562b684b676046bbd763e50 200 SUPERFAMILY SSF46785 50 184 3.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS09100 031a52e95562b684b676046bbd763e50 200 Pfam PF01047 MarR family 80 134 1.6E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS09100 031a52e95562b684b676046bbd763e50 200 Gene3D G3DSA:1.10.10.10 45 184 2.2E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS07885 61881317d53f9b6e3663bebf9b713425 336 SUPERFAMILY SSF161098 101 317 4.09E-11 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS07885 61881317d53f9b6e3663bebf9b713425 336 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 329 2.1E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS07885 61881317d53f9b6e3663bebf9b713425 336 Gene3D G3DSA:1.10.3720.10 2 318 1.1E-25 T 28-03-2018 CFK41_RS00820 2af85255ee187b6b8519c928455aeadc 681 Gene3D G3DSA:2.120.10.30 309 649 7.6E-6 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CFK41_RS00820 2af85255ee187b6b8519c928455aeadc 681 Pfam PF05787 Bacterial protein of unknown function (DUF839) 112 649 4.2E-152 T 28-03-2018 IPR008557 Protein of unknown function DUF839 CFK41_RS00820 2af85255ee187b6b8519c928455aeadc 681 ProSitePatterns PS00276 Channel forming colicins signature. 444 455 - T 28-03-2018 IPR000293 Channel forming colicin, C-terminal cytotoxic GO:0016021|GO:0019835|GO:0050829 CFK41_RS00820 2af85255ee187b6b8519c928455aeadc 681 SUPERFAMILY SSF63829 482 629 1.61E-6 T 28-03-2018 CFK41_RS00820 2af85255ee187b6b8519c928455aeadc 681 SUPERFAMILY SSF63829 363 454 1.61E-6 T 28-03-2018 CFK41_RS16035 f3b0a13571136a3af43eb848f69a35b9 420 Pfam PF00565 Staphylococcal nuclease homologue 68 174 4.3E-14 T 28-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CFK41_RS16035 f3b0a13571136a3af43eb848f69a35b9 420 Gene3D G3DSA:1.20.1000.10 133 339 2.2E-9 T 28-03-2018 CFK41_RS16035 f3b0a13571136a3af43eb848f69a35b9 420 SUPERFAMILY SSF50199 45 175 1.96E-26 T 28-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CFK41_RS16035 f3b0a13571136a3af43eb848f69a35b9 420 Gene3D G3DSA:2.40.50.90 42 132 1.2E-20 T 28-03-2018 IPR035437 Staphylococcal nuclease (SNase-like), OB-fold/extended TUDOR domain CFK41_RS16035 f3b0a13571136a3af43eb848f69a35b9 420 SMART SM00318 43 175 8.7E-25 T 28-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CFK41_RS10480 fe270ccdff8c9c660a0dc01566f8fd69 177 Gene3D G3DSA:1.20.1560.10 35 169 5.4E-4 T 28-03-2018 CFK41_RS10480 fe270ccdff8c9c660a0dc01566f8fd69 177 Pfam PF03703 Bacterial PH domain 89 165 2.9E-16 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CFK41_RS06610 1b56505e1c8575fa9e6287e949f8508e 107 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 30 99 7.1E-20 T 28-03-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 CFK41_RS06610 1b56505e1c8575fa9e6287e949f8508e 107 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 22 105 15.609 T 28-03-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS CFK41_RS06610 1b56505e1c8575fa9e6287e949f8508e 107 Gene3D G3DSA:3.30.1390.10 30 101 2.3E-24 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CFK41_RS06610 1b56505e1c8575fa9e6287e949f8508e 107 SUPERFAMILY SSF54736 26 102 4.97E-22 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CFK41_RS00550 ec1db99dab82ee6c3245010c1ac12713 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.8E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS00550 ec1db99dab82ee6c3245010c1ac12713 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.8E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS00550 ec1db99dab82ee6c3245010c1ac12713 195 Gene3D G3DSA:1.10.357.10 7 195 5.6E-29 T 28-03-2018 CFK41_RS00550 ec1db99dab82ee6c3245010c1ac12713 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 4.5E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS00550 ec1db99dab82ee6c3245010c1ac12713 195 SUPERFAMILY SSF48498 81 192 1.2E-17 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CFK41_RS00550 ec1db99dab82ee6c3245010c1ac12713 195 SUPERFAMILY SSF46689 5 79 2.31E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS14050 e161e15b8e9ad0dc9f6892ca3d429af4 386 SUPERFAMILY SSF55874 270 379 7.12E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS14050 e161e15b8e9ad0dc9f6892ca3d429af4 386 SMART SM00387 289 380 7.5E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS14050 e161e15b8e9ad0dc9f6892ca3d429af4 386 Pfam PF07730 Histidine kinase 179 244 1.4E-14 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CFK41_RS14050 e161e15b8e9ad0dc9f6892ca3d429af4 386 Gene3D G3DSA:3.30.565.10 251 386 7.6E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS14050 e161e15b8e9ad0dc9f6892ca3d429af4 386 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 294 378 2.3E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS08210 0e1d3ced7996f9cf4c78fc8eddd32740 308 SUPERFAMILY SSF53850 90 297 4.62E-26 T 28-03-2018 CFK41_RS08210 0e1d3ced7996f9cf4c78fc8eddd32740 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 4.5E-12 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CFK41_RS08210 0e1d3ced7996f9cf4c78fc8eddd32740 308 Pfam PF03466 LysR substrate binding domain 88 294 1.5E-24 T 28-03-2018 IPR005119 LysR, substrate-binding CFK41_RS08210 0e1d3ced7996f9cf4c78fc8eddd32740 308 Gene3D G3DSA:1.10.10.10 258 307 0.32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS08210 0e1d3ced7996f9cf4c78fc8eddd32740 308 Gene3D G3DSA:3.40.190.10 182 257 9.6E-16 T 28-03-2018 CFK41_RS08210 0e1d3ced7996f9cf4c78fc8eddd32740 308 Gene3D G3DSA:1.10.10.10 1 84 1.8E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS08210 0e1d3ced7996f9cf4c78fc8eddd32740 308 Gene3D G3DSA:3.40.190.10 92 181 6.6E-10 T 28-03-2018 CFK41_RS08210 0e1d3ced7996f9cf4c78fc8eddd32740 308 SUPERFAMILY SSF46785 1 109 1.9E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS05000 d8298f0030b9de8c445cb7e4a3942c56 471 SUPERFAMILY SSF48557 13 465 7.66E-139 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CFK41_RS05000 d8298f0030b9de8c445cb7e4a3942c56 471 Gene3D G3DSA:1.10.40.30 420 469 9.8E-24 T 28-03-2018 CFK41_RS05000 d8298f0030b9de8c445cb7e4a3942c56 471 PRINTS PR00145 Argininosuccinate lyase family signature 177 197 4.4E-5 T 28-03-2018 CFK41_RS05000 d8298f0030b9de8c445cb7e4a3942c56 471 PRINTS PR00145 Argininosuccinate lyase family signature 319 335 4.4E-5 T 28-03-2018 CFK41_RS05000 d8298f0030b9de8c445cb7e4a3942c56 471 Hamap MF_00743 Fumarate hydratase class II [fumC]. 13 469 77.496 T 28-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CFK41_RS05000 d8298f0030b9de8c445cb7e4a3942c56 471 Gene3D G3DSA:1.10.275.10 11 140 3.9E-51 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CFK41_RS05000 d8298f0030b9de8c445cb7e4a3942c56 471 Gene3D G3DSA:1.20.200.10 141 419 2.4E-75 T 28-03-2018 CFK41_RS05000 d8298f0030b9de8c445cb7e4a3942c56 471 Pfam PF00206 Lyase 21 344 2.5E-99 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CFK41_RS05000 d8298f0030b9de8c445cb7e4a3942c56 471 PRINTS PR00149 Fumarate lyase superfamily signature 136 154 2.4E-34 T 28-03-2018 IPR000362 Fumarate lyase family CFK41_RS05000 d8298f0030b9de8c445cb7e4a3942c56 471 PRINTS PR00149 Fumarate lyase superfamily signature 182 200 2.4E-34 T 28-03-2018 IPR000362 Fumarate lyase family CFK41_RS05000 d8298f0030b9de8c445cb7e4a3942c56 471 PRINTS PR00149 Fumarate lyase superfamily signature 273 300 2.4E-34 T 28-03-2018 IPR000362 Fumarate lyase family CFK41_RS05000 d8298f0030b9de8c445cb7e4a3942c56 471 PRINTS PR00149 Fumarate lyase superfamily signature 319 335 2.4E-34 T 28-03-2018 IPR000362 Fumarate lyase family CFK41_RS05000 d8298f0030b9de8c445cb7e4a3942c56 471 ProSitePatterns PS00163 Fumarate lyases signature. 319 328 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CFK41_RS05000 d8298f0030b9de8c445cb7e4a3942c56 471 Pfam PF10415 Fumarase C C-terminus 410 467 1.4E-20 T 28-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CFK41_RS00545 57bf295d3b394bfe0ad0e4d3a7f02243 353 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 146 3.0E-25 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CFK41_RS00545 57bf295d3b394bfe0ad0e4d3a7f02243 353 SUPERFAMILY SSF50129 10 171 2.67E-43 T 28-03-2018 IPR011032 GroES-like CFK41_RS00545 57bf295d3b394bfe0ad0e4d3a7f02243 353 Gene3D G3DSA:3.40.50.720 178 338 5.7E-21 T 28-03-2018 CFK41_RS00545 57bf295d3b394bfe0ad0e4d3a7f02243 353 Gene3D G3DSA:3.90.180.10 1 177 3.0E-44 T 28-03-2018 CFK41_RS00545 57bf295d3b394bfe0ad0e4d3a7f02243 353 SUPERFAMILY SSF51735 151 313 8.97E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS00545 57bf295d3b394bfe0ad0e4d3a7f02243 353 Pfam PF00107 Zinc-binding dehydrogenase 188 308 4.7E-14 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CFK41_RS00545 57bf295d3b394bfe0ad0e4d3a7f02243 353 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 64 78 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CFK41_RS00545 57bf295d3b394bfe0ad0e4d3a7f02243 353 SMART SM00829 11 343 1.4E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CFK41_RS16150 300a82b6b40047000d862af1aca17c69 170 Gene3D G3DSA:2.60.40.1260 28 157 2.5E-24 T 28-03-2018 IPR001322 Lamin Tail Domain CFK41_RS16150 300a82b6b40047000d862af1aca17c69 170 Pfam PF00932 Lamin Tail Domain 35 150 1.9E-23 T 28-03-2018 IPR001322 Lamin Tail Domain CFK41_RS16150 300a82b6b40047000d862af1aca17c69 170 SUPERFAMILY SSF74853 60 150 1.7E-18 T 28-03-2018 IPR001322 Lamin Tail Domain CFK41_RS09230 f81ea0de10edff317e6d7171581a012f 332 Pfam PF02650 WhiA C-terminal HTH domain 222 301 6.7E-19 T 28-03-2018 IPR023054 Sporulation regulator WhiA, C-terminal CFK41_RS09230 f81ea0de10edff317e6d7171581a012f 332 Pfam PF14527 WhiA LAGLIDADG-like domain 127 218 6.9E-22 T 28-03-2018 CFK41_RS09230 f81ea0de10edff317e6d7171581a012f 332 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 5 304 2.8E-96 T 28-03-2018 IPR033981 Sporulation regulator WhiA-like CFK41_RS09230 f81ea0de10edff317e6d7171581a012f 332 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 20 104 1.3E-23 T 28-03-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain CFK41_RS09230 f81ea0de10edff317e6d7171581a012f 332 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 306 28.667 T 28-03-2018 IPR003802 Sporulation regulator WhiA GO:0043937 CFK41_RS05350 5d3613ff4f6b04a06dd96109f62f88b9 307 SUPERFAMILY SSF51735 120 262 1.48E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS05350 5d3613ff4f6b04a06dd96109f62f88b9 307 Pfam PF13602 Zinc-binding dehydrogenase 201 302 4.0E-13 T 28-03-2018 CFK41_RS05350 5d3613ff4f6b04a06dd96109f62f88b9 307 SMART SM00829 10 303 5.2E-14 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CFK41_RS05350 5d3613ff4f6b04a06dd96109f62f88b9 307 Gene3D G3DSA:3.90.180.10 1 153 3.6E-48 T 28-03-2018 CFK41_RS05350 5d3613ff4f6b04a06dd96109f62f88b9 307 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 90 2.6E-8 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CFK41_RS05350 5d3613ff4f6b04a06dd96109f62f88b9 307 Gene3D G3DSA:3.90.180.10 154 304 2.8E-12 T 28-03-2018 CFK41_RS05350 5d3613ff4f6b04a06dd96109f62f88b9 307 SUPERFAMILY SSF50129 1 150 1.46E-36 T 28-03-2018 IPR011032 GroES-like CFK41_RS13005 d2152f6bc31bbd6a61ddd15fcf765955 517 Pfam PF00501 AMP-binding enzyme 8 426 1.6E-104 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CFK41_RS13005 d2152f6bc31bbd6a61ddd15fcf765955 517 Gene3D G3DSA:3.40.50.980 180 334 2.9E-48 T 28-03-2018 CFK41_RS13005 d2152f6bc31bbd6a61ddd15fcf765955 517 Gene3D G3DSA:3.30.300.30 420 517 1.3E-29 T 28-03-2018 CFK41_RS13005 d2152f6bc31bbd6a61ddd15fcf765955 517 Gene3D G3DSA:3.40.50.980 2 179 1.3E-41 T 28-03-2018 CFK41_RS13005 d2152f6bc31bbd6a61ddd15fcf765955 517 ProSitePatterns PS00455 Putative AMP-binding domain signature. 174 185 - T 28-03-2018 IPR020845 AMP-binding, conserved site CFK41_RS13005 d2152f6bc31bbd6a61ddd15fcf765955 517 SUPERFAMILY SSF56801 7 516 5.36E-154 T 28-03-2018 CFK41_RS13005 d2152f6bc31bbd6a61ddd15fcf765955 517 Pfam PF13193 AMP-binding enzyme C-terminal domain 435 510 2.4E-21 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CFK41_RS13005 d2152f6bc31bbd6a61ddd15fcf765955 517 Gene3D G3DSA:2.30.38.10 335 419 5.7E-25 T 28-03-2018 CFK41_RS08070 237294aec49ace71742c6dd22ef820b3 328 Gene3D G3DSA:1.10.8.60 135 217 7.9E-9 T 28-03-2018 CFK41_RS08070 237294aec49ace71742c6dd22ef820b3 328 SUPERFAMILY SSF48019 210 323 2.98E-16 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CFK41_RS08070 237294aec49ace71742c6dd22ef820b3 328 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 11 322 4.2E-29 T 28-03-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 CFK41_RS08070 237294aec49ace71742c6dd22ef820b3 328 Gene3D G3DSA:3.40.50.300 5 125 3.9E-11 T 28-03-2018 CFK41_RS08070 237294aec49ace71742c6dd22ef820b3 328 Gene3D G3DSA:1.20.272.10 218 328 6.7E-25 T 28-03-2018 CFK41_RS08070 237294aec49ace71742c6dd22ef820b3 328 Pfam PF06144 DNA polymerase III, delta subunit 38 173 2.3E-7 T 28-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 CFK41_RS05330 17140dab92a6fbd59884e15165a28fde 428 Gene3D G3DSA:1.20.140.10 217 391 6.5E-15 T 28-03-2018 CFK41_RS05330 17140dab92a6fbd59884e15165a28fde 428 SUPERFAMILY SSF56645 15 213 3.01E-35 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CFK41_RS05330 17140dab92a6fbd59884e15165a28fde 428 SUPERFAMILY SSF47203 224 366 2.09E-10 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CFK41_RS05330 17140dab92a6fbd59884e15165a28fde 428 PIRSF PIRSF016578 2 84 2.6E-7 T 28-03-2018 CFK41_RS05330 17140dab92a6fbd59884e15165a28fde 428 PIRSF PIRSF016578 124 377 6.6E-12 T 28-03-2018 CFK41_RS05330 17140dab92a6fbd59884e15165a28fde 428 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 228 365 5.2E-12 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CFK41_RS05330 17140dab92a6fbd59884e15165a28fde 428 Gene3D G3DSA:1.10.540.10 2 113 1.5E-12 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CFK41_RS05330 17140dab92a6fbd59884e15165a28fde 428 Gene3D G3DSA:2.40.110.10 116 216 1.5E-10 T 28-03-2018 CFK41_RS05330 17140dab92a6fbd59884e15165a28fde 428 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 110 2.8E-6 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CFK41_RS07945 6b142696b5356f1a3b636206626bd25c 728 SUPERFAMILY SSF52540 332 378 1.03E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS07945 6b142696b5356f1a3b636206626bd25c 728 SUPERFAMILY SSF52540 471 719 1.03E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS07945 6b142696b5356f1a3b636206626bd25c 728 SUPERFAMILY SSF52540 181 260 1.03E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS07945 6b142696b5356f1a3b636206626bd25c 728 Gene3D G3DSA:3.40.50.300 187 575 8.2E-29 T 28-03-2018 CFK41_RS07945 6b142696b5356f1a3b636206626bd25c 728 Gene3D G3DSA:3.40.50.300 584 728 5.6E-8 T 28-03-2018 CFK41_RS07945 6b142696b5356f1a3b636206626bd25c 728 Pfam PF13245 AAA domain 193 563 2.7E-11 T 28-03-2018 CFK41_RS11900 8e3d9628950d8d6de672017706a9e115 249 PIRSF PIRSF000386 1 248 5.5E-84 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CFK41_RS11900 8e3d9628950d8d6de672017706a9e115 249 SUPERFAMILY SSF75217 1 241 4.88E-83 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CFK41_RS11900 8e3d9628950d8d6de672017706a9e115 249 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 240 3.8E-70 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CFK41_RS11900 8e3d9628950d8d6de672017706a9e115 249 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 236 3.9E-59 T 28-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CFK41_RS11900 8e3d9628950d8d6de672017706a9e115 249 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 249 96.477 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CFK41_RS11900 8e3d9628950d8d6de672017706a9e115 249 Gene3D G3DSA:1.10.1270.20 180 249 4.7E-27 T 28-03-2018 CFK41_RS11900 8e3d9628950d8d6de672017706a9e115 249 Gene3D G3DSA:3.40.1280.10 1 179 1.2E-70 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CFK41_RS07050 f8c9800fdcb74039d0a96fde8a301ed4 271 PRINTS PR00125 ATP synthase delta subunit signature 99 118 3.9E-9 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07050 f8c9800fdcb74039d0a96fde8a301ed4 271 PRINTS PR00125 ATP synthase delta subunit signature 229 244 3.9E-9 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07050 f8c9800fdcb74039d0a96fde8a301ed4 271 PRINTS PR00125 ATP synthase delta subunit signature 244 262 3.9E-9 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07050 f8c9800fdcb74039d0a96fde8a301ed4 271 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 105 269 4.2E-17 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07050 f8c9800fdcb74039d0a96fde8a301ed4 271 Hamap MF_01416 ATP synthase subunit delta [atpD]. 95 271 13.045 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07050 f8c9800fdcb74039d0a96fde8a301ed4 271 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 231 250 - T 28-03-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07050 f8c9800fdcb74039d0a96fde8a301ed4 271 Gene3D G3DSA:1.10.520.20 14 102 9.0E-6 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07050 f8c9800fdcb74039d0a96fde8a301ed4 271 Gene3D G3DSA:1.10.520.20 104 200 1.2E-9 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07050 f8c9800fdcb74039d0a96fde8a301ed4 271 Pfam PF00213 ATP synthase delta (OSCP) subunit 105 269 2.7E-24 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS04785 8aaee2c16eae92303fdaed09eaa2d144 440 Gene3D G3DSA:3.40.47.10 2 290 3.5E-33 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CFK41_RS04785 8aaee2c16eae92303fdaed09eaa2d144 440 PIRSF PIRSF000429 4 439 4.6E-94 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CFK41_RS04785 8aaee2c16eae92303fdaed09eaa2d144 440 Gene3D G3DSA:3.40.47.10 291 435 7.2E-19 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CFK41_RS04785 8aaee2c16eae92303fdaed09eaa2d144 440 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 90 108 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CFK41_RS04785 8aaee2c16eae92303fdaed09eaa2d144 440 SUPERFAMILY SSF53901 9 289 4.07E-47 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CFK41_RS04785 8aaee2c16eae92303fdaed09eaa2d144 440 Pfam PF00108 Thiolase, N-terminal domain 12 280 1.1E-38 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CFK41_RS04785 8aaee2c16eae92303fdaed09eaa2d144 440 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 12 436 1.6E-105 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CFK41_RS04785 8aaee2c16eae92303fdaed09eaa2d144 440 Pfam PF02803 Thiolase, C-terminal domain 290 436 2.7E-28 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CFK41_RS04785 8aaee2c16eae92303fdaed09eaa2d144 440 SUPERFAMILY SSF53901 288 436 7.68E-25 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CFK41_RS13455 dc9deaa906a7914a6b2201a572b9f4dc 325 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 11 323 4.6E-116 T 28-03-2018 IPR014188 Acrylyl-CoA reductase AcuI CFK41_RS13455 dc9deaa906a7914a6b2201a572b9f4dc 325 Gene3D G3DSA:3.90.180.10 1 135 2.8E-22 T 28-03-2018 CFK41_RS13455 dc9deaa906a7914a6b2201a572b9f4dc 325 Pfam PF00107 Zinc-binding dehydrogenase 157 265 1.6E-11 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CFK41_RS13455 dc9deaa906a7914a6b2201a572b9f4dc 325 SMART SM00829 10 321 3.1E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CFK41_RS13455 dc9deaa906a7914a6b2201a572b9f4dc 325 SUPERFAMILY SSF50129 1 141 4.04E-31 T 28-03-2018 IPR011032 GroES-like CFK41_RS13455 dc9deaa906a7914a6b2201a572b9f4dc 325 Gene3D G3DSA:3.40.50.720 136 309 5.7E-21 T 28-03-2018 CFK41_RS13455 dc9deaa906a7914a6b2201a572b9f4dc 325 SUPERFAMILY SSF51735 113 282 4.0E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS05555 eb73f1957c56f04090e0a89163fca4cc 390 SUPERFAMILY SSF51556 55 343 9.9E-46 T 28-03-2018 IPR032466 Metal-dependent hydrolase CFK41_RS05555 eb73f1957c56f04090e0a89163fca4cc 390 Gene3D G3DSA:2.30.40.10 321 382 3.7E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS05555 eb73f1957c56f04090e0a89163fca4cc 390 Gene3D G3DSA:2.30.40.10 3 70 3.7E-20 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS05555 eb73f1957c56f04090e0a89163fca4cc 390 Gene3D G3DSA:3.20.20.140 71 320 7.3E-24 T 28-03-2018 CFK41_RS05555 eb73f1957c56f04090e0a89163fca4cc 390 SUPERFAMILY SSF51338 4 56 2.52E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS05555 eb73f1957c56f04090e0a89163fca4cc 390 SUPERFAMILY SSF51338 342 378 2.52E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS05555 eb73f1957c56f04090e0a89163fca4cc 390 Pfam PF01979 Amidohydrolase family 53 364 4.3E-23 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CFK41_RS07665 9a507b7fe39b3ac357c790df2ed2574a 361 Gene3D G3DSA:1.10.3720.10 25 349 2.4E-39 T 28-03-2018 CFK41_RS07665 9a507b7fe39b3ac357c790df2ed2574a 361 SUPERFAMILY SSF161098 224 348 2.88E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS07665 9a507b7fe39b3ac357c790df2ed2574a 361 SUPERFAMILY SSF161098 116 182 2.88E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS07665 9a507b7fe39b3ac357c790df2ed2574a 361 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 136 361 3.5E-39 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS09915 7f9e4876422c924f89e0c2f593eb8425 122 Pfam PF00085 Thioredoxin 4 99 7.2E-24 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CFK41_RS09915 7f9e4876422c924f89e0c2f593eb8425 122 Gene3D G3DSA:3.40.30.10 2 122 1.4E-30 T 28-03-2018 CFK41_RS09915 7f9e4876422c924f89e0c2f593eb8425 122 PRINTS PR00421 Thioredoxin family signature 67 78 2.7E-6 T 28-03-2018 CFK41_RS09915 7f9e4876422c924f89e0c2f593eb8425 122 PRINTS PR00421 Thioredoxin family signature 20 28 2.7E-6 T 28-03-2018 CFK41_RS09915 7f9e4876422c924f89e0c2f593eb8425 122 PRINTS PR00421 Thioredoxin family signature 28 37 2.7E-6 T 28-03-2018 CFK41_RS09915 7f9e4876422c924f89e0c2f593eb8425 122 SUPERFAMILY SSF52833 5 102 1.32E-29 T 28-03-2018 IPR012336 Thioredoxin-like fold CFK41_RS09915 7f9e4876422c924f89e0c2f593eb8425 122 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 101 1.8E-30 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CFK41_RS09915 7f9e4876422c924f89e0c2f593eb8425 122 PIRSF PIRSF000077 1 105 1.2E-25 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CFK41_RS09915 7f9e4876422c924f89e0c2f593eb8425 122 ProSitePatterns PS00194 Thioredoxin family active site. 21 39 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CFK41_RS14560 bb3b0b77c5457464b98fbbde17c6b022 514 Gene3D G3DSA:3.40.605.10 6 251 1.1E-38 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CFK41_RS14560 bb3b0b77c5457464b98fbbde17c6b022 514 Gene3D G3DSA:3.40.309.10 252 433 1.2E-20 T 28-03-2018 CFK41_RS14560 bb3b0b77c5457464b98fbbde17c6b022 514 Pfam PF00171 Aldehyde dehydrogenase family 20 438 6.1E-35 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CFK41_RS14560 bb3b0b77c5457464b98fbbde17c6b022 514 SUPERFAMILY SSF53720 17 473 1.2E-73 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CFK41_RS16220 13babc946537777e930930b3419fd014 417 Pfam PF01546 Peptidase family M20/M25/M40 101 374 2.2E-9 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CFK41_RS16220 13babc946537777e930930b3419fd014 417 Pfam PF07687 Peptidase dimerisation domain 186 276 1.8E-5 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CFK41_RS16220 13babc946537777e930930b3419fd014 417 SUPERFAMILY SSF53187 297 388 1.29E-51 T 28-03-2018 CFK41_RS16220 13babc946537777e930930b3419fd014 417 SUPERFAMILY SSF53187 27 198 1.29E-51 T 28-03-2018 CFK41_RS16220 13babc946537777e930930b3419fd014 417 Gene3D G3DSA:3.40.630.10 16 298 1.8E-42 T 28-03-2018 CFK41_RS16220 13babc946537777e930930b3419fd014 417 Gene3D G3DSA:3.40.630.10 304 408 1.1E-9 T 28-03-2018 CFK41_RS16220 13babc946537777e930930b3419fd014 417 PIRSF PIRSF037226 14 410 3.4E-106 T 28-03-2018 IPR017144 Peptidase M20A, amidohydrolase, predicted CFK41_RS16220 13babc946537777e930930b3419fd014 417 SUPERFAMILY SSF55031 185 287 6.28E-17 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CFK41_RS16220 13babc946537777e930930b3419fd014 417 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 35 359 8.7E-54 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CFK41_RS08670 9741596570744094a44801eae7d1f58e 127 SUPERFAMILY SSF54534 17 125 2.36E-34 T 28-03-2018 CFK41_RS08670 9741596570744094a44801eae7d1f58e 127 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 32 121 5.8E-29 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain CFK41_RS08670 9741596570744094a44801eae7d1f58e 127 Gene3D G3DSA:3.10.50.40 4 127 3.2E-37 T 28-03-2018 CFK41_RS13340 f12f28ade19e9a9f7d446ee7d2ae215a 225 Gene3D G3DSA:1.10.150.20 1 64 1.8E-5 T 28-03-2018 CFK41_RS13340 f12f28ade19e9a9f7d446ee7d2ae215a 225 Pfam PF08818 Domain of unknown function (DU1801) 114 217 2.3E-7 T 28-03-2018 IPR014922 Domain of unknown function DUF1801 CFK41_RS09490 e91865bf522a5ade2ef3404d337424bc 402 Gene3D G3DSA:3.30.300.10 14 151 7.1E-45 T 28-03-2018 CFK41_RS09490 e91865bf522a5ade2ef3404d337424bc 402 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 129 139 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CFK41_RS09490 e91865bf522a5ade2ef3404d337424bc 402 PIRSF PIRSF000497 1 402 1.9E-160 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CFK41_RS09490 e91865bf522a5ade2ef3404d337424bc 402 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 5 402 54.125 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CFK41_RS09490 e91865bf522a5ade2ef3404d337424bc 402 Pfam PF02772 S-adenosylmethionine synthetase, central domain 128 250 1.4E-38 T 28-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CFK41_RS09490 e91865bf522a5ade2ef3404d337424bc 402 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 252 391 2.7E-65 T 28-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CFK41_RS09490 e91865bf522a5ade2ef3404d337424bc 402 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 8 401 4.0E-163 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CFK41_RS09490 e91865bf522a5ade2ef3404d337424bc 402 SUPERFAMILY SSF55973 126 251 8.63E-39 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CFK41_RS09490 e91865bf522a5ade2ef3404d337424bc 402 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 8 104 1.2E-40 T 28-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CFK41_RS09490 e91865bf522a5ade2ef3404d337424bc 402 SUPERFAMILY SSF55973 8 113 6.67E-45 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CFK41_RS09490 e91865bf522a5ade2ef3404d337424bc 402 Gene3D G3DSA:3.30.300.10 158 277 1.4E-34 T 28-03-2018 CFK41_RS09490 e91865bf522a5ade2ef3404d337424bc 402 Gene3D G3DSA:3.30.300.10 278 402 1.1E-43 T 28-03-2018 CFK41_RS09490 e91865bf522a5ade2ef3404d337424bc 402 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 278 286 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CFK41_RS09490 e91865bf522a5ade2ef3404d337424bc 402 SUPERFAMILY SSF55973 252 399 1.14E-64 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CFK41_RS11605 3d0b48ba28869e111b6f8c05e8101d78 204 Gene3D G3DSA:3.40.50.150 10 203 9.0E-35 T 28-03-2018 CFK41_RS11605 3d0b48ba28869e111b6f8c05e8101d78 204 SUPERFAMILY SSF53335 26 196 1.49E-32 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS11605 3d0b48ba28869e111b6f8c05e8101d78 204 Pfam PF05175 Methyltransferase small domain 28 198 2.0E-28 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CFK41_RS02185 ffa52ac1811e53296c1fed3d14b66b8c 322 SUPERFAMILY SSF52540 9 241 2.3E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS02185 ffa52ac1811e53296c1fed3d14b66b8c 322 Pfam PF00005 ABC transporter 27 169 6.4E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS02185 ffa52ac1811e53296c1fed3d14b66b8c 322 SMART SM00382 35 218 3.9E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS02185 ffa52ac1811e53296c1fed3d14b66b8c 322 Gene3D G3DSA:3.40.50.300 9 295 1.3E-63 T 28-03-2018 CFK41_RS05370 a9028cddb62da85b3bc34ca96276f289 481 Pfam PF07690 Major Facilitator Superfamily 29 419 4.1E-49 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS05370 a9028cddb62da85b3bc34ca96276f289 481 Gene3D G3DSA:1.20.1250.20 269 481 3.8E-29 T 28-03-2018 CFK41_RS05370 a9028cddb62da85b3bc34ca96276f289 481 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 24 428 6.2E-108 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CFK41_RS05370 a9028cddb62da85b3bc34ca96276f289 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 27 51 1.5E-6 T 28-03-2018 CFK41_RS05370 a9028cddb62da85b3bc34ca96276f289 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 118 138 1.5E-6 T 28-03-2018 CFK41_RS05370 a9028cddb62da85b3bc34ca96276f289 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 148 172 1.5E-6 T 28-03-2018 CFK41_RS05370 a9028cddb62da85b3bc34ca96276f289 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 312 336 1.5E-6 T 28-03-2018 CFK41_RS05370 a9028cddb62da85b3bc34ca96276f289 481 Gene3D G3DSA:1.20.1250.20 16 208 1.3E-31 T 28-03-2018 CFK41_RS05370 a9028cddb62da85b3bc34ca96276f289 481 SUPERFAMILY SSF103473 14 207 5.75E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS05370 a9028cddb62da85b3bc34ca96276f289 481 SUPERFAMILY SSF103473 258 473 5.75E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS11285 35944edc4c6252aa84df90004b0ccd6b 137 Pfam PF02416 mttA/Hcf106 family 9 37 5.8E-7 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 CFK41_RS11285 35944edc4c6252aa84df90004b0ccd6b 137 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 6 26 7.8E-9 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CFK41_RS11285 35944edc4c6252aa84df90004b0ccd6b 137 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 26 45 7.8E-9 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CFK41_RS01860 0866a3b240097b725d031d2d9ea38947 260 Gene3D G3DSA:3.20.20.150 1 253 1.7E-31 T 28-03-2018 CFK41_RS01860 0866a3b240097b725d031d2d9ea38947 260 SUPERFAMILY SSF51658 2 241 2.07E-32 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS01860 0866a3b240097b725d031d2d9ea38947 260 Pfam PF01261 Xylose isomerase-like TIM barrel 21 193 4.5E-20 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS09650 4328f0e0835e798bfcf7e774221e5a1c 223 Gene3D G3DSA:1.10.10.10 127 219 1.4E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS09650 4328f0e0835e798bfcf7e774221e5a1c 223 Gene3D G3DSA:3.40.50.2300 1 126 9.9E-38 T 28-03-2018 CFK41_RS09650 4328f0e0835e798bfcf7e774221e5a1c 223 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS09650 4328f0e0835e798bfcf7e774221e5a1c 223 SMART SM00421 153 210 2.4E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS09650 4328f0e0835e798bfcf7e774221e5a1c 223 SUPERFAMILY SSF46894 146 216 4.08E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CFK41_RS09650 4328f0e0835e798bfcf7e774221e5a1c 223 SUPERFAMILY SSF52172 1 132 3.84E-33 T 28-03-2018 IPR011006 CheY-like superfamily CFK41_RS09650 4328f0e0835e798bfcf7e774221e5a1c 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 210 1.1E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS09650 4328f0e0835e798bfcf7e774221e5a1c 223 Pfam PF00072 Response regulator receiver domain 4 115 1.7E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS09650 4328f0e0835e798bfcf7e774221e5a1c 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 5.1E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS09650 4328f0e0835e798bfcf7e774221e5a1c 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 5.1E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS09650 4328f0e0835e798bfcf7e774221e5a1c 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 5.1E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS09650 4328f0e0835e798bfcf7e774221e5a1c 223 SMART SM00448 2 115 2.0E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS01665 89bd9375eecc3c570b494dd865ceb307 361 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 24 34 6.9E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS01665 89bd9375eecc3c570b494dd865ceb307 361 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 6.9E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS01665 89bd9375eecc3c570b494dd865ceb307 361 ProSitePatterns PS00356 LacI-type HTH domain signature. 15 33 - T 28-03-2018 CFK41_RS01665 89bd9375eecc3c570b494dd865ceb307 361 Gene3D G3DSA:1.10.260.40 14 68 1.5E-20 T 28-03-2018 CFK41_RS01665 89bd9375eecc3c570b494dd865ceb307 361 Gene3D G3DSA:3.40.50.2300 177 352 3.6E-48 T 28-03-2018 CFK41_RS01665 89bd9375eecc3c570b494dd865ceb307 361 Gene3D G3DSA:3.40.50.2300 69 176 2.0E-17 T 28-03-2018 CFK41_RS01665 89bd9375eecc3c570b494dd865ceb307 361 SUPERFAMILY SSF53822 73 353 2.78E-53 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS01665 89bd9375eecc3c570b494dd865ceb307 361 Pfam PF13377 Periplasmic binding protein-like domain 183 350 5.2E-34 T 28-03-2018 CFK41_RS01665 89bd9375eecc3c570b494dd865ceb307 361 SUPERFAMILY SSF47413 12 70 8.04E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS01665 89bd9375eecc3c570b494dd865ceb307 361 SMART SM00354 12 82 1.7E-20 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS01665 89bd9375eecc3c570b494dd865ceb307 361 Pfam PF00356 Bacterial regulatory proteins, lacI family 14 59 8.7E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS17250 bd95a1eaf72a38073a1d8175c1ce6f3d 202 Gene3D G3DSA:3.40.50.880 4 201 1.7E-43 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS17250 bd95a1eaf72a38073a1d8175c1ce6f3d 202 SUPERFAMILY SSF52317 6 192 1.39E-45 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS17250 bd95a1eaf72a38073a1d8175c1ce6f3d 202 PIRSF PIRSF005639 2 198 8.4E-63 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CFK41_RS17250 bd95a1eaf72a38073a1d8175c1ce6f3d 202 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 6 190 1.5E-58 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CFK41_RS17250 bd95a1eaf72a38073a1d8175c1ce6f3d 202 Pfam PF01174 SNO glutamine amidotransferase family 9 194 4.3E-49 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CFK41_RS17250 bd95a1eaf72a38073a1d8175c1ce6f3d 202 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 7 193 34.283 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CFK41_RS17250 bd95a1eaf72a38073a1d8175c1ce6f3d 202 ProSitePatterns PS01236 PdxT/SNO family family signature. 44 54 - T 28-03-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CFK41_RS00535 21333aedfeb018f709d21b026957c8fb 406 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 396 3.8E-17 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS00535 21333aedfeb018f709d21b026957c8fb 406 Gene3D G3DSA:3.60.10.10 1 406 1.4E-43 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS00535 21333aedfeb018f709d21b026957c8fb 406 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 197 403 6.1E-36 T 28-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 CFK41_RS00535 21333aedfeb018f709d21b026957c8fb 406 SUPERFAMILY SSF56219 2 94 9.85E-43 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS00535 21333aedfeb018f709d21b026957c8fb 406 SUPERFAMILY SSF56219 213 406 9.85E-43 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS06095 1f601a5ddaeb280b3a329c9e183421f2 591 Gene3D G3DSA:3.40.50.20 10 131 9.1E-50 T 28-03-2018 CFK41_RS06095 1f601a5ddaeb280b3a329c9e183421f2 591 Pfam PF02785 Biotin carboxylase C-terminal domain 342 454 3.7E-35 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CFK41_RS06095 1f601a5ddaeb280b3a329c9e183421f2 591 Pfam PF00364 Biotin-requiring enzyme 523 589 4.0E-16 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CFK41_RS06095 1f601a5ddaeb280b3a329c9e183421f2 591 Gene3D G3DSA:3.30.470.20 218 457 8.6E-91 T 28-03-2018 CFK41_RS06095 1f601a5ddaeb280b3a329c9e183421f2 591 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 294 301 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CFK41_RS06095 1f601a5ddaeb280b3a329c9e183421f2 591 Gene3D G3DSA:2.40.50.100 520 591 3.0E-18 T 28-03-2018 CFK41_RS06095 1f601a5ddaeb280b3a329c9e183421f2 591 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 546 563 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CFK41_RS06095 1f601a5ddaeb280b3a329c9e183421f2 591 SUPERFAMILY SSF51230 516 590 8.51E-20 T 28-03-2018 IPR011053 Single hybrid motif CFK41_RS06095 1f601a5ddaeb280b3a329c9e183421f2 591 SMART SM00878 342 454 2.6E-55 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CFK41_RS06095 1f601a5ddaeb280b3a329c9e183421f2 591 SUPERFAMILY SSF56059 91 339 3.54E-57 T 28-03-2018 CFK41_RS06095 1f601a5ddaeb280b3a329c9e183421f2 591 Gene3D G3DSA:3.30.1490.20 132 217 3.3E-17 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CFK41_RS06095 1f601a5ddaeb280b3a329c9e183421f2 591 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 123 330 3.1E-73 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CFK41_RS06095 1f601a5ddaeb280b3a329c9e183421f2 591 SUPERFAMILY SSF52440 6 121 8.63E-46 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CFK41_RS06095 1f601a5ddaeb280b3a329c9e183421f2 591 Pfam PF00289 Biotin carboxylase, N-terminal domain 11 118 1.1E-42 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CFK41_RS06095 1f601a5ddaeb280b3a329c9e183421f2 591 SUPERFAMILY SSF51246 337 455 2.51E-35 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CFK41_RS08335 b9a8bebb1996bf0a2991003cdfbb71be 218 SMART SM00448 19 132 3.3E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS08335 b9a8bebb1996bf0a2991003cdfbb71be 218 Pfam PF00072 Response regulator receiver domain 21 132 1.6E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS08335 b9a8bebb1996bf0a2991003cdfbb71be 218 Gene3D G3DSA:1.10.10.10 143 218 2.0E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS08335 b9a8bebb1996bf0a2991003cdfbb71be 218 SUPERFAMILY SSF52172 20 145 6.69E-29 T 28-03-2018 IPR011006 CheY-like superfamily CFK41_RS08335 b9a8bebb1996bf0a2991003cdfbb71be 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 9.7E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS08335 b9a8bebb1996bf0a2991003cdfbb71be 218 SMART SM00421 155 212 3.9E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS08335 b9a8bebb1996bf0a2991003cdfbb71be 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 3.5E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS08335 b9a8bebb1996bf0a2991003cdfbb71be 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 3.5E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS08335 b9a8bebb1996bf0a2991003cdfbb71be 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 3.5E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS08335 b9a8bebb1996bf0a2991003cdfbb71be 218 Gene3D G3DSA:3.40.50.2300 18 142 2.2E-32 T 28-03-2018 CFK41_RS08335 b9a8bebb1996bf0a2991003cdfbb71be 218 SUPERFAMILY SSF46894 147 218 3.03E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CFK41_RS10950 4d425bdfd35acc5b5df4cb48d09c117c 579 SUPERFAMILY SSF52016 400 577 1.57E-55 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CFK41_RS10950 4d425bdfd35acc5b5df4cb48d09c117c 579 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 22 578 44.11 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CFK41_RS10950 4d425bdfd35acc5b5df4cb48d09c117c 579 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 140 150 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CFK41_RS10950 4d425bdfd35acc5b5df4cb48d09c117c 579 Pfam PF00920 Dehydratase family 52 575 1.2E-205 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CFK41_RS10950 4d425bdfd35acc5b5df4cb48d09c117c 579 SUPERFAMILY SSF143975 14 399 7.32E-131 T 28-03-2018 CFK41_RS10950 4d425bdfd35acc5b5df4cb48d09c117c 579 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 36 577 1.0E-208 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CFK41_RS10950 4d425bdfd35acc5b5df4cb48d09c117c 579 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 486 497 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CFK41_RS12225 c2de05dfd0048519c5d4cf0df174d90b 248 Gene3D G3DSA:1.10.150.240 29 112 6.6E-24 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CFK41_RS12225 c2de05dfd0048519c5d4cf0df174d90b 248 Gene3D G3DSA:3.40.50.1000 113 248 1.6E-22 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS12225 c2de05dfd0048519c5d4cf0df174d90b 248 Pfam PF13419 Haloacid dehalogenase-like hydrolase 19 213 1.3E-12 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS12225 c2de05dfd0048519c5d4cf0df174d90b 248 SUPERFAMILY SSF56784 16 247 6.24E-38 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS12225 c2de05dfd0048519c5d4cf0df174d90b 248 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 112 220 1.7E-12 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CFK41_RS12990 c4cbf0250649dcb5abddc3e3dd5ac74c 337 Gene3D G3DSA:1.10.260.40 5 60 7.9E-21 T 28-03-2018 CFK41_RS12990 c4cbf0250649dcb5abddc3e3dd5ac74c 337 Pfam PF13377 Periplasmic binding protein-like domain 172 333 8.4E-27 T 28-03-2018 CFK41_RS12990 c4cbf0250649dcb5abddc3e3dd5ac74c 337 SUPERFAMILY SSF47413 3 62 2.46E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS12990 c4cbf0250649dcb5abddc3e3dd5ac74c 337 ProSitePatterns PS00356 LacI-type HTH domain signature. 7 25 - T 28-03-2018 CFK41_RS12990 c4cbf0250649dcb5abddc3e3dd5ac74c 337 SMART SM00354 4 74 6.3E-25 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS12990 c4cbf0250649dcb5abddc3e3dd5ac74c 337 SUPERFAMILY SSF53822 64 334 1.86E-53 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS12990 c4cbf0250649dcb5abddc3e3dd5ac74c 337 Gene3D G3DSA:3.40.50.2300 169 336 1.8E-43 T 28-03-2018 CFK41_RS12990 c4cbf0250649dcb5abddc3e3dd5ac74c 337 Gene3D G3DSA:3.40.50.2300 61 168 8.3E-20 T 28-03-2018 CFK41_RS12990 c4cbf0250649dcb5abddc3e3dd5ac74c 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 51 2.4E-18 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS04610 c48d01967cea5fe26c9f1be358bb5121 139 Pfam PF00252 Ribosomal protein L16p/L10e 4 131 1.8E-46 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CFK41_RS04610 c48d01967cea5fe26c9f1be358bb5121 139 SUPERFAMILY SSF54686 1 136 2.49E-54 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CFK41_RS04610 c48d01967cea5fe26c9f1be358bb5121 139 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 37.967 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04610 c48d01967cea5fe26c9f1be358bb5121 139 PRINTS PR00060 Ribosomal protein L16 signature 24 36 2.7E-39 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04610 c48d01967cea5fe26c9f1be358bb5121 139 PRINTS PR00060 Ribosomal protein L16 signature 58 87 2.7E-39 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04610 c48d01967cea5fe26c9f1be358bb5121 139 PRINTS PR00060 Ribosomal protein L16 signature 88 117 2.7E-39 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04610 c48d01967cea5fe26c9f1be358bb5121 139 PRINTS PR00060 Ribosomal protein L16 signature 42 53 2.7E-39 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04610 c48d01967cea5fe26c9f1be358bb5121 139 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS04610 c48d01967cea5fe26c9f1be358bb5121 139 Gene3D G3DSA:3.90.1170.10 3 139 1.9E-49 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CFK41_RS04610 c48d01967cea5fe26c9f1be358bb5121 139 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 5.0E-55 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS16870 6e042c9f8ca8363321f1bdce4576ab91 256 Pfam PF00455 DeoR C terminal sensor domain 80 236 2.9E-45 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CFK41_RS16870 6e042c9f8ca8363321f1bdce4576ab91 256 Gene3D G3DSA:3.40.50.1360 77 241 1.8E-32 T 28-03-2018 CFK41_RS16870 6e042c9f8ca8363321f1bdce4576ab91 256 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CFK41_RS16870 6e042c9f8ca8363321f1bdce4576ab91 256 SUPERFAMILY SSF46785 4 61 1.02E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS16870 6e042c9f8ca8363321f1bdce4576ab91 256 SMART SM01134 77 237 2.0E-57 T 28-03-2018 CFK41_RS16870 6e042c9f8ca8363321f1bdce4576ab91 256 SMART SM00420 6 58 1.2E-17 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CFK41_RS16870 6e042c9f8ca8363321f1bdce4576ab91 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.9E-6 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CFK41_RS16870 6e042c9f8ca8363321f1bdce4576ab91 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.9E-6 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CFK41_RS16870 6e042c9f8ca8363321f1bdce4576ab91 256 Gene3D G3DSA:1.10.10.10 1 69 6.2E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS16870 6e042c9f8ca8363321f1bdce4576ab91 256 SUPERFAMILY SSF100950 81 236 8.72E-27 T 28-03-2018 CFK41_RS16870 6e042c9f8ca8363321f1bdce4576ab91 256 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 1.6E-16 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CFK41_RS16310 754b959cfdd61ea942803ad61974d9c1 806 Gene3D G3DSA:3.40.50.1700 31 298 2.9E-58 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CFK41_RS16310 754b959cfdd61ea942803ad61974d9c1 806 SMART SM01217 331 407 1.2E-23 T 28-03-2018 IPR026891 Fibronectin type III-like domain CFK41_RS16310 754b959cfdd61ea942803ad61974d9c1 806 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 45 298 2.2E-38 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CFK41_RS16310 754b959cfdd61ea942803ad61974d9c1 806 PRINTS PR00133 Glycosyl hydrolase family 3 signature 713 731 9.2E-27 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS16310 754b959cfdd61ea942803ad61974d9c1 806 PRINTS PR00133 Glycosyl hydrolase family 3 signature 542 558 9.2E-27 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS16310 754b959cfdd61ea942803ad61974d9c1 806 PRINTS PR00133 Glycosyl hydrolase family 3 signature 566 585 9.2E-27 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS16310 754b959cfdd61ea942803ad61974d9c1 806 PRINTS PR00133 Glycosyl hydrolase family 3 signature 643 659 9.2E-27 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS16310 754b959cfdd61ea942803ad61974d9c1 806 PRINTS PR00133 Glycosyl hydrolase family 3 signature 612 628 9.2E-27 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS16310 754b959cfdd61ea942803ad61974d9c1 806 Gene3D G3DSA:3.20.20.300 477 806 7.2E-82 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS16310 754b959cfdd61ea942803ad61974d9c1 806 Pfam PF14310 Fibronectin type III-like domain 331 406 5.8E-17 T 28-03-2018 IPR026891 Fibronectin type III-like domain CFK41_RS16310 754b959cfdd61ea942803ad61974d9c1 806 SUPERFAMILY SSF51445 497 799 8.21E-70 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS16310 754b959cfdd61ea942803ad61974d9c1 806 Gene3D G3DSA:2.60.40.10 299 421 7.3E-26 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS16310 754b959cfdd61ea942803ad61974d9c1 806 SUPERFAMILY SSF52279 142 301 1.7E-34 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CFK41_RS16310 754b959cfdd61ea942803ad61974d9c1 806 SUPERFAMILY SSF52279 45 112 1.7E-34 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CFK41_RS16310 754b959cfdd61ea942803ad61974d9c1 806 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 541 762 7.1E-50 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS07375 0ccd9a88a5d8c9d4fc7b73bc62ac82de 267 SMART SM00563 55 173 4.0E-25 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CFK41_RS07375 0ccd9a88a5d8c9d4fc7b73bc62ac82de 267 Pfam PF01553 Acyltransferase 43 169 1.1E-20 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CFK41_RS07375 0ccd9a88a5d8c9d4fc7b73bc62ac82de 267 Gene3D G3DSA:3.40.1130.10 35 242 5.2E-38 T 28-03-2018 CFK41_RS07375 0ccd9a88a5d8c9d4fc7b73bc62ac82de 267 SUPERFAMILY SSF69593 28 232 1.14E-32 T 28-03-2018 CFK41_RS15115 c0714b85703e5a638af8e7173897eedd 547 Gene3D G3DSA:3.40.190.10 84 231 1.3E-11 T 28-03-2018 CFK41_RS15115 c0714b85703e5a638af8e7173897eedd 547 Gene3D G3DSA:3.40.190.10 232 537 2.4E-16 T 28-03-2018 CFK41_RS15115 c0714b85703e5a638af8e7173897eedd 547 SUPERFAMILY SSF53850 25 32 1.81E-41 T 28-03-2018 CFK41_RS15115 c0714b85703e5a638af8e7173897eedd 547 SUPERFAMILY SSF53850 86 534 1.81E-41 T 28-03-2018 CFK41_RS10280 334ec1846247a58a39da4f2f9457204e 538 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 243 282 8.1E-5 T 28-03-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 CFK41_RS10280 334ec1846247a58a39da4f2f9457204e 538 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 50 205 8.9E-13 T 28-03-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 CFK41_RS10280 334ec1846247a58a39da4f2f9457204e 538 Pfam PF16192 C-terminal four TMM region of protein-O-mannosyltransferase 347 537 1.8E-18 T 28-03-2018 IPR032421 Protein O-mannosyl-transferase, C-terminal four TM domain KEGG: 00500+2.4.1.10|KEGG: 00514+2.4.1.109|KEGG: 00515+2.4.1.109|MetaCyc: PWY-822|Reactome: R-HSA-5173105 CFK41_RS13425 0ec9b349f9568481841862a41c338a93 676 Gene3D G3DSA:3.40.930.10 532 675 5.7E-31 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CFK41_RS13425 0ec9b349f9568481841862a41c338a93 676 SUPERFAMILY SSF52794 421 506 3.24E-22 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CFK41_RS13425 0ec9b349f9568481841862a41c338a93 676 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 536 671 5.5E-27 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CFK41_RS13425 0ec9b349f9568481841862a41c338a93 676 SUPERFAMILY SSF55804 535 672 9.55E-34 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CFK41_RS13425 0ec9b349f9568481841862a41c338a93 676 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 580 596 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain CFK41_RS13425 0ec9b349f9568481841862a41c338a93 676 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 422 506 1.7E-10 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CFK41_RS13425 0ec9b349f9568481841862a41c338a93 676 Pfam PF02378 Phosphotransferase system, EIIC 25 313 1.7E-20 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CFK41_RS13425 0ec9b349f9568481841862a41c338a93 676 Gene3D G3DSA:3.40.50.2300 408 513 8.3E-17 T 28-03-2018 CFK41_RS03580 81f0fc25679d386d734edb17ebf02c2c 298 Gene3D G3DSA:3.40.630.30 1 134 2.8E-8 T 28-03-2018 CFK41_RS03580 81f0fc25679d386d734edb17ebf02c2c 298 SUPERFAMILY SSF55729 102 289 9.45E-32 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS03580 81f0fc25679d386d734edb17ebf02c2c 298 Hamap MF_01698 Mycothiol acetyltransferase [mshD]. 1 294 29.481 T 28-03-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 CFK41_RS03580 81f0fc25679d386d734edb17ebf02c2c 298 Pfam PF00583 Acetyltransferase (GNAT) family 185 283 6.6E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS03580 81f0fc25679d386d734edb17ebf02c2c 298 TIGRFAM TIGR03448 mycothiol_MshD: mycothiol synthase 4 290 3.0E-67 T 28-03-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 CFK41_RS03580 81f0fc25679d386d734edb17ebf02c2c 298 Gene3D G3DSA:3.40.630.30 157 297 8.3E-28 T 28-03-2018 CFK41_RS03580 81f0fc25679d386d734edb17ebf02c2c 298 SUPERFAMILY SSF55729 14 126 1.22E-8 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS09775 fbcfafd3f753e955fd44ed3977879c22 401 Hamap MF_00296 Homoserine O-acetyltransferase [metX]. 40 401 43.568 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CFK41_RS09775 fbcfafd3f753e955fd44ed3977879c22 401 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 55 398 1.2E-128 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CFK41_RS09775 fbcfafd3f753e955fd44ed3977879c22 401 PIRSF PIRSF000443 42 400 1.7E-124 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CFK41_RS09775 fbcfafd3f753e955fd44ed3977879c22 401 Gene3D G3DSA:3.40.50.1820 62 400 4.3E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS09775 fbcfafd3f753e955fd44ed3977879c22 401 Pfam PF00561 alpha/beta hydrolase fold 83 385 6.1E-33 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CFK41_RS09775 fbcfafd3f753e955fd44ed3977879c22 401 SUPERFAMILY SSF53474 48 399 9.46E-96 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS10780 02e7aec06e94bcd1d809c219926e147b 309 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 292 3.0E-72 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CFK41_RS10780 02e7aec06e94bcd1d809c219926e147b 309 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 304 2.6E-135 T 28-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CFK41_RS10780 02e7aec06e94bcd1d809c219926e147b 309 Gene3D G3DSA:3.40.50.1100 22 133 9.0E-36 T 28-03-2018 CFK41_RS10780 02e7aec06e94bcd1d809c219926e147b 309 Gene3D G3DSA:3.40.50.1100 134 308 5.7E-58 T 28-03-2018 CFK41_RS10780 02e7aec06e94bcd1d809c219926e147b 309 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 304 1.5E-132 T 28-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CFK41_RS10780 02e7aec06e94bcd1d809c219926e147b 309 SUPERFAMILY SSF53686 2 306 2.62E-102 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CFK41_RS10780 02e7aec06e94bcd1d809c219926e147b 309 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CFK41_RS02875 fdcd52e539e3731eb3a17601bcb1d705 690 Gene3D G3DSA:1.20.1560.10 25 405 7.4E-88 T 28-03-2018 CFK41_RS02875 fdcd52e539e3731eb3a17601bcb1d705 690 Pfam PF00664 ABC transporter transmembrane region 62 374 7.4E-59 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS02875 fdcd52e539e3731eb3a17601bcb1d705 690 Pfam PF00005 ABC transporter 438 586 1.4E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS02875 fdcd52e539e3731eb3a17601bcb1d705 690 SUPERFAMILY SSF90123 134 404 4.45E-85 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS02875 fdcd52e539e3731eb3a17601bcb1d705 690 SUPERFAMILY SSF90123 49 93 4.45E-85 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS02875 fdcd52e539e3731eb3a17601bcb1d705 690 SMART SM00382 446 632 9.5E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS02875 fdcd52e539e3731eb3a17601bcb1d705 690 Gene3D G3DSA:3.40.50.300 406 662 7.7E-74 T 28-03-2018 CFK41_RS02875 fdcd52e539e3731eb3a17601bcb1d705 690 ProSitePatterns PS00211 ABC transporters family signature. 558 572 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS02875 fdcd52e539e3731eb3a17601bcb1d705 690 SUPERFAMILY SSF52540 417 657 7.1E-88 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS09990 0c5fcf23a25b081becd1058f112e0335 666 Gene3D G3DSA:3.40.50.800 560 666 8.3E-23 T 28-03-2018 IPR004154 Anticodon-binding CFK41_RS09990 0c5fcf23a25b081becd1058f112e0335 666 Gene3D G3DSA:3.30.54.20 139 185 2.7E-16 T 28-03-2018 CFK41_RS09990 0c5fcf23a25b081becd1058f112e0335 666 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 350 557 5.4E-33 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS09990 0c5fcf23a25b081becd1058f112e0335 666 Gene3D G3DSA:3.30.980.10 65 138 6.4E-17 T 28-03-2018 CFK41_RS09990 0c5fcf23a25b081becd1058f112e0335 666 SMART SM00863 176 232 2.0E-20 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CFK41_RS09990 0c5fcf23a25b081becd1058f112e0335 666 Gene3D G3DSA:3.30.980.10 186 235 1.2E-12 T 28-03-2018 CFK41_RS09990 0c5fcf23a25b081becd1058f112e0335 666 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 62 662 32.5 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CFK41_RS09990 0c5fcf23a25b081becd1058f112e0335 666 SUPERFAMILY SSF52954 557 661 9.06E-27 T 28-03-2018 IPR004154 Anticodon-binding CFK41_RS09990 0c5fcf23a25b081becd1058f112e0335 666 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 183 232 9.5E-12 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CFK41_RS09990 0c5fcf23a25b081becd1058f112e0335 666 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 68 658 2.3E-186 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CFK41_RS09990 0c5fcf23a25b081becd1058f112e0335 666 Pfam PF03129 Anticodon binding domain 569 656 2.7E-17 T 28-03-2018 IPR004154 Anticodon-binding CFK41_RS09990 0c5fcf23a25b081becd1058f112e0335 666 PRINTS PR01047 Threonyl-tRNA synthetase signature 356 384 1.3E-49 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CFK41_RS09990 0c5fcf23a25b081becd1058f112e0335 666 PRINTS PR01047 Threonyl-tRNA synthetase signature 535 548 1.3E-49 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CFK41_RS09990 0c5fcf23a25b081becd1058f112e0335 666 PRINTS PR01047 Threonyl-tRNA synthetase signature 389 412 1.3E-49 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CFK41_RS09990 0c5fcf23a25b081becd1058f112e0335 666 PRINTS PR01047 Threonyl-tRNA synthetase signature 492 520 1.3E-49 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CFK41_RS09990 0c5fcf23a25b081becd1058f112e0335 666 PRINTS PR01047 Threonyl-tRNA synthetase signature 562 574 1.3E-49 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CFK41_RS09990 0c5fcf23a25b081becd1058f112e0335 666 Gene3D G3DSA:3.30.930.10 236 559 1.7E-103 T 28-03-2018 CFK41_RS09990 0c5fcf23a25b081becd1058f112e0335 666 SUPERFAMILY SSF55186 60 253 6.8E-48 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CFK41_RS09990 0c5fcf23a25b081becd1058f112e0335 666 SUPERFAMILY SSF55681 256 554 5.17E-89 T 28-03-2018 CFK41_RS12070 41ce1d210b83f3c0fa09c69dfde3ebe0 259 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 5 193 1.2E-22 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CFK41_RS12070 41ce1d210b83f3c0fa09c69dfde3ebe0 259 SUPERFAMILY SSF56300 5 241 5.32E-39 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CFK41_RS12070 41ce1d210b83f3c0fa09c69dfde3ebe0 259 PIRSF PIRSF000883 4 249 1.6E-50 T 28-03-2018 IPR011152 Phosphoesterase MJ0912 CFK41_RS12070 41ce1d210b83f3c0fa09c69dfde3ebe0 259 Gene3D G3DSA:3.60.21.10 4 246 1.3E-29 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CFK41_RS05960 2e5a07f60a56cc71fcf53d51d90c0d3d 159 PRINTS PR01483 Fatty acid synthase signature 29 51 4.1E-6 T 28-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CFK41_RS05960 2e5a07f60a56cc71fcf53d51d90c0d3d 159 PRINTS PR01483 Fatty acid synthase signature 51 72 4.1E-6 T 28-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CFK41_RS05960 2e5a07f60a56cc71fcf53d51d90c0d3d 159 Pfam PF01575 MaoC like domain 18 127 4.7E-23 T 28-03-2018 IPR002539 MaoC-like domain CFK41_RS05960 2e5a07f60a56cc71fcf53d51d90c0d3d 159 SUPERFAMILY SSF54637 13 142 3.39E-25 T 28-03-2018 IPR029069 HotDog domain CFK41_RS05960 2e5a07f60a56cc71fcf53d51d90c0d3d 159 Gene3D G3DSA:3.10.129.10 6 147 1.7E-31 T 28-03-2018 CFK41_RS08295 10c4e41094f89b61446c0119e3eff45e 441 SMART SM00471 67 229 3.6E-10 T 28-03-2018 IPR003607 HD/PDEase domain CFK41_RS08295 10c4e41094f89b61446c0119e3eff45e 441 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 10 420 31.033 T 28-03-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 CFK41_RS08295 10c4e41094f89b61446c0119e3eff45e 441 Pfam PF01966 HD domain 71 218 1.9E-17 T 28-03-2018 IPR006674 HD domain CFK41_RS08295 10c4e41094f89b61446c0119e3eff45e 441 Pfam PF13286 Phosphohydrolase-associated domain 326 417 1.8E-19 T 28-03-2018 IPR026875 Phosphohydrolase-associated domain CFK41_RS08295 10c4e41094f89b61446c0119e3eff45e 441 Gene3D G3DSA:1.10.3210.10 15 210 3.9E-61 T 28-03-2018 CFK41_RS08295 10c4e41094f89b61446c0119e3eff45e 441 Gene3D G3DSA:1.10.3410.10 211 347 6.6E-27 T 28-03-2018 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain CFK41_RS08295 10c4e41094f89b61446c0119e3eff45e 441 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 34 420 4.3E-83 T 28-03-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 CFK41_RS08295 10c4e41094f89b61446c0119e3eff45e 441 SUPERFAMILY SSF109604 200 423 1.84E-58 T 28-03-2018 CFK41_RS08295 10c4e41094f89b61446c0119e3eff45e 441 SUPERFAMILY SSF109604 23 170 1.84E-58 T 28-03-2018 CFK41_RS17330 dae4e14d6e840666c5739944fd549131 142 Gene3D G3DSA:1.10.10.10 1 45 2.3E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS17330 dae4e14d6e840666c5739944fd549131 142 Pfam PF01037 Lrp/AsnC ligand binding domain 70 137 7.5E-17 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CFK41_RS17330 dae4e14d6e840666c5739944fd549131 142 SUPERFAMILY SSF54909 65 139 1.88E-15 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CFK41_RS17330 dae4e14d6e840666c5739944fd549131 142 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 49 3.3E-13 T 28-03-2018 CFK41_RS17330 dae4e14d6e840666c5739944fd549131 142 SMART SM00344 2 108 3.0E-19 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CFK41_RS17330 dae4e14d6e840666c5739944fd549131 142 SUPERFAMILY SSF46785 2 56 7.08E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS17330 dae4e14d6e840666c5739944fd549131 142 Gene3D G3DSA:3.30.70.920 46 135 2.3E-19 T 28-03-2018 CFK41_RS17330 dae4e14d6e840666c5739944fd549131 142 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 2.3E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CFK41_RS17330 dae4e14d6e840666c5739944fd549131 142 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 2.3E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CFK41_RS17330 dae4e14d6e840666c5739944fd549131 142 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 2.3E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CFK41_RS00880 5474b1178cfea03af1dbc0b67e94b9d6 533 Gene3D G3DSA:3.40.710.10 11 376 7.2E-62 T 28-03-2018 CFK41_RS00880 5474b1178cfea03af1dbc0b67e94b9d6 533 Pfam PF00144 Beta-lactamase 43 365 5.6E-46 T 28-03-2018 IPR001466 Beta-lactamase-related CFK41_RS00880 5474b1178cfea03af1dbc0b67e94b9d6 533 SUPERFAMILY SSF56601 31 364 1.48E-60 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CFK41_RS04000 d712c60ca7d6426cce4ec6c168a0d9c8 322 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 9 322 3.3E-145 T 28-03-2018 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CFK41_RS04000 d712c60ca7d6426cce4ec6c168a0d9c8 322 Pfam PF00268 Ribonucleotide reductase, small chain 12 283 1.2E-87 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CFK41_RS04000 d712c60ca7d6426cce4ec6c168a0d9c8 322 Gene3D G3DSA:1.10.620.20 3 295 5.4E-77 T 28-03-2018 CFK41_RS04000 d712c60ca7d6426cce4ec6c168a0d9c8 322 PIRSF PIRSF000355 2 319 3.3E-78 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CFK41_RS04000 d712c60ca7d6426cce4ec6c168a0d9c8 322 SUPERFAMILY SSF47240 6 322 2.1E-103 T 28-03-2018 IPR009078 Ferritin-like superfamily CFK41_RS04000 d712c60ca7d6426cce4ec6c168a0d9c8 322 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 100 116 - T 28-03-2018 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CFK41_RS13140 dee7ddc06bf9ad3c4680b37f87a716e0 277 Pfam PF13462 Thioredoxin 90 251 2.3E-16 T 28-03-2018 IPR012336 Thioredoxin-like fold CFK41_RS13140 dee7ddc06bf9ad3c4680b37f87a716e0 277 Gene3D G3DSA:3.40.30.10 81 263 2.9E-31 T 28-03-2018 CFK41_RS13140 dee7ddc06bf9ad3c4680b37f87a716e0 277 SUPERFAMILY SSF52833 77 251 9.7E-18 T 28-03-2018 IPR012336 Thioredoxin-like fold CFK41_RS12795 e53e3872c9f7d8e2d90a7a5d5c5778b7 227 Gene3D G3DSA:3.20.20.70 1 224 4.1E-40 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS12795 e53e3872c9f7d8e2d90a7a5d5c5778b7 227 Pfam PF04131 Putative N-acetylmannosamine-6-phosphate epimerase 30 225 4.2E-52 T 28-03-2018 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 CFK41_RS12795 e53e3872c9f7d8e2d90a7a5d5c5778b7 227 Hamap MF_01235 Putative N-acetylmannosamine-6-phosphate 2-epimerase [nanE]. 6 225 33.669 T 28-03-2018 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 CFK41_RS12795 e53e3872c9f7d8e2d90a7a5d5c5778b7 227 SUPERFAMILY SSF51366 8 223 3.58E-51 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CFK41_RS16930 57b5b9f1a2be9cc6c0afe3455f901fec 536 Pfam PF00083 Sugar (and other) transporter 31 526 4.0E-97 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CFK41_RS16930 57b5b9f1a2be9cc6c0afe3455f901fec 536 SUPERFAMILY SSF103473 298 523 1.22E-62 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS16930 57b5b9f1a2be9cc6c0afe3455f901fec 536 SUPERFAMILY SSF103473 228 264 1.22E-62 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS16930 57b5b9f1a2be9cc6c0afe3455f901fec 536 SUPERFAMILY SSF103473 32 183 1.22E-62 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS16930 57b5b9f1a2be9cc6c0afe3455f901fec 536 ProSitePatterns PS00217 Sugar transport proteins signature 2. 132 157 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CFK41_RS16930 57b5b9f1a2be9cc6c0afe3455f901fec 536 ProSitePatterns PS00216 Sugar transport proteins signature 1. 90 107 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CFK41_RS16930 57b5b9f1a2be9cc6c0afe3455f901fec 536 PRINTS PR00171 Sugar transporter signature 450 462 2.5E-25 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CFK41_RS16930 57b5b9f1a2be9cc6c0afe3455f901fec 536 PRINTS PR00171 Sugar transporter signature 325 335 2.5E-25 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CFK41_RS16930 57b5b9f1a2be9cc6c0afe3455f901fec 536 PRINTS PR00171 Sugar transporter signature 127 146 2.5E-25 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CFK41_RS16930 57b5b9f1a2be9cc6c0afe3455f901fec 536 PRINTS PR00171 Sugar transporter signature 427 448 2.5E-25 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CFK41_RS16930 57b5b9f1a2be9cc6c0afe3455f901fec 536 PRINTS PR00171 Sugar transporter signature 39 49 2.5E-25 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CFK41_RS16930 57b5b9f1a2be9cc6c0afe3455f901fec 536 Gene3D G3DSA:1.20.1250.20 285 531 1.6E-30 T 28-03-2018 CFK41_RS16930 57b5b9f1a2be9cc6c0afe3455f901fec 536 Gene3D G3DSA:1.20.1250.20 11 266 5.6E-33 T 28-03-2018 CFK41_RS02650 b105ca73aaa712979ed0c8bcbb8c32c6 298 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 190 218 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CFK41_RS02650 b105ca73aaa712979ed0c8bcbb8c32c6 298 Gene3D G3DSA:3.40.50.720 6 296 1.8E-73 T 28-03-2018 CFK41_RS02650 b105ca73aaa712979ed0c8bcbb8c32c6 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 55 72 8.7E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02650 b105ca73aaa712979ed0c8bcbb8c32c6 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 193 8.7E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02650 b105ca73aaa712979ed0c8bcbb8c32c6 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 222 8.7E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02650 b105ca73aaa712979ed0c8bcbb8c32c6 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 241 8.7E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02650 b105ca73aaa712979ed0c8bcbb8c32c6 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 142 8.7E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02650 b105ca73aaa712979ed0c8bcbb8c32c6 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 259 279 8.7E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02650 b105ca73aaa712979ed0c8bcbb8c32c6 298 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 183 191 3.8E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02650 b105ca73aaa712979ed0c8bcbb8c32c6 298 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 203 222 3.8E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02650 b105ca73aaa712979ed0c8bcbb8c32c6 298 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 142 3.8E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02650 b105ca73aaa712979ed0c8bcbb8c32c6 298 SUPERFAMILY SSF51735 53 294 4.23E-75 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS02650 b105ca73aaa712979ed0c8bcbb8c32c6 298 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 60 294 6.7E-59 T 28-03-2018 CFK41_RS14495 a655a29e5df88daed7a0b8b0b10ca892 385 SUPERFAMILY SSF53067 87 376 1.13E-31 T 28-03-2018 CFK41_RS14495 a655a29e5df88daed7a0b8b0b10ca892 385 Gene3D G3DSA:1.10.10.10 5 81 1.2E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS14495 a655a29e5df88daed7a0b8b0b10ca892 385 SUPERFAMILY SSF46785 10 66 1.2E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS14495 a655a29e5df88daed7a0b8b0b10ca892 385 Gene3D G3DSA:3.30.420.40 82 197 3.7E-17 T 28-03-2018 CFK41_RS14495 a655a29e5df88daed7a0b8b0b10ca892 385 Pfam PF00480 ROK family 87 374 6.9E-36 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CFK41_RS14495 a655a29e5df88daed7a0b8b0b10ca892 385 Gene3D G3DSA:3.30.420.40 198 381 1.2E-32 T 28-03-2018 CFK41_RS00925 84e5e454d265818a8a3c8cebba720717 713 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 629 641 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CFK41_RS00925 84e5e454d265818a8a3c8cebba720717 713 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 24 41 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CFK41_RS00925 84e5e454d265818a8a3c8cebba720717 713 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 567 686 5.9E-38 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CFK41_RS00925 84e5e454d265818a8a3c8cebba720717 713 SUPERFAMILY SSF55604 11 85 4.58E-18 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CFK41_RS00925 84e5e454d265818a8a3c8cebba720717 713 Pfam PF00367 phosphotransferase system, EIIB 13 46 4.1E-16 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CFK41_RS00925 84e5e454d265818a8a3c8cebba720717 713 SUPERFAMILY SSF51261 562 710 4.19E-48 T 28-03-2018 IPR011055 Duplicated hybrid motif CFK41_RS00925 84e5e454d265818a8a3c8cebba720717 713 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 566 689 1.6E-43 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CFK41_RS00925 84e5e454d265818a8a3c8cebba720717 713 Pfam PF02378 Phosphotransferase system, EIIC 125 422 3.4E-29 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CFK41_RS00925 84e5e454d265818a8a3c8cebba720717 713 Gene3D G3DSA:2.70.70.10 557 713 2.9E-50 T 28-03-2018 CFK41_RS00925 84e5e454d265818a8a3c8cebba720717 713 Gene3D G3DSA:3.30.1360.60 9 85 3.8E-23 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CFK41_RS06405 ba7be71d4907ef63f3117370b321bab9 168 Gene3D G3DSA:3.30.530.20 2 166 0.0013 T 28-03-2018 IPR023393 START-like domain CFK41_RS06405 ba7be71d4907ef63f3117370b321bab9 168 Pfam PF10698 Protein of unknown function (DUF2505) 7 161 1.2E-35 T 28-03-2018 IPR019639 Protein of unknown function DUF2505 CFK41_RS15845 6c5a33cff6482301f037279ed1cfd2b9 503 Pfam PF01943 Polysaccharide biosynthesis protein 17 299 5.0E-15 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CFK41_RS15845 6c5a33cff6482301f037279ed1cfd2b9 503 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 353 488 1.1E-8 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CFK41_RS16875 5b3b1c66ddb763913d5c513b6f30260a 514 SUPERFAMILY SSF56327 364 504 8.16E-36 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CFK41_RS16875 5b3b1c66ddb763913d5c513b6f30260a 514 SUPERFAMILY SSF56327 170 298 8.16E-36 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CFK41_RS16875 5b3b1c66ddb763913d5c513b6f30260a 514 SUPERFAMILY SSF51735 1 169 4.05E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS16875 5b3b1c66ddb763913d5c513b6f30260a 514 Gene3D G3DSA:3.40.50.720 1 169 2.7E-30 T 28-03-2018 CFK41_RS16875 5b3b1c66ddb763913d5c513b6f30260a 514 Gene3D G3DSA:3.90.110.10 170 513 3.7E-82 T 28-03-2018 CFK41_RS16875 5b3b1c66ddb763913d5c513b6f30260a 514 Pfam PF02056 Family 4 glycosyl hydrolase 2 185 1.2E-40 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CFK41_RS16875 5b3b1c66ddb763913d5c513b6f30260a 514 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 141 171 - T 28-03-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 CFK41_RS16875 5b3b1c66ddb763913d5c513b6f30260a 514 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 205 487 9.5E-37 T 28-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 CFK41_RS16875 5b3b1c66ddb763913d5c513b6f30260a 514 PRINTS PR00732 Glycosyl hydrolase family 4 signature 166 177 2.7E-32 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CFK41_RS16875 5b3b1c66ddb763913d5c513b6f30260a 514 PRINTS PR00732 Glycosyl hydrolase family 4 signature 98 111 2.7E-32 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CFK41_RS16875 5b3b1c66ddb763913d5c513b6f30260a 514 PRINTS PR00732 Glycosyl hydrolase family 4 signature 112 132 2.7E-32 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CFK41_RS16875 5b3b1c66ddb763913d5c513b6f30260a 514 PRINTS PR00732 Glycosyl hydrolase family 4 signature 77 93 2.7E-32 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CFK41_RS16875 5b3b1c66ddb763913d5c513b6f30260a 514 PRINTS PR00732 Glycosyl hydrolase family 4 signature 141 158 2.7E-32 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CFK41_RS16875 5b3b1c66ddb763913d5c513b6f30260a 514 PRINTS PR00732 Glycosyl hydrolase family 4 signature 2 17 2.7E-32 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CFK41_RS09925 4ec2b6ec1d1166206d5957872625f914 552 Gene3D G3DSA:1.20.1480.30 435 536 0.0026 T 28-03-2018 CFK41_RS09925 4ec2b6ec1d1166206d5957872625f914 552 Pfam PF03993 Domain of Unknown Function (DUF349) 227 298 1.1E-5 T 28-03-2018 IPR007139 Protein of unknown function DUF349 CFK41_RS09925 4ec2b6ec1d1166206d5957872625f914 552 Pfam PF03993 Domain of Unknown Function (DUF349) 312 384 5.5E-17 T 28-03-2018 IPR007139 Protein of unknown function DUF349 CFK41_RS09925 4ec2b6ec1d1166206d5957872625f914 552 Pfam PF03993 Domain of Unknown Function (DUF349) 391 461 7.3E-19 T 28-03-2018 IPR007139 Protein of unknown function DUF349 CFK41_RS16385 3d4c57cf01b66430ac2b560f0baf4156 555 SUPERFAMILY SSF53850 30 551 7.97E-68 T 28-03-2018 CFK41_RS16385 3d4c57cf01b66430ac2b560f0baf4156 555 Gene3D G3DSA:3.40.190.10 204 425 2.4E-26 T 28-03-2018 CFK41_RS16385 3d4c57cf01b66430ac2b560f0baf4156 555 Gene3D G3DSA:3.40.190.10 63 203 1.6E-7 T 28-03-2018 CFK41_RS16385 3d4c57cf01b66430ac2b560f0baf4156 555 Pfam PF13416 Bacterial extracellular solute-binding protein 85 401 2.1E-19 T 28-03-2018 CFK41_RS11435 a97071e6b538a79554297a5d444bce1d 1033 Pfam PF09261 Alpha mannosidase middle domain 517 595 1.4E-24 T 28-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 CFK41_RS11435 a97071e6b538a79554297a5d444bce1d 1033 Gene3D G3DSA:1.20.1270.50 516 623 7.3E-31 T 28-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 CFK41_RS11435 a97071e6b538a79554297a5d444bce1d 1033 SUPERFAMILY SSF88713 248 515 6.67E-74 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CFK41_RS11435 a97071e6b538a79554297a5d444bce1d 1033 SMART SM00872 517 596 2.7E-31 T 28-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 CFK41_RS11435 a97071e6b538a79554297a5d444bce1d 1033 Gene3D G3DSA:3.20.110.10 201 458 1.1E-77 T 28-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain CFK41_RS11435 a97071e6b538a79554297a5d444bce1d 1033 SUPERFAMILY SSF88688 516 617 1.08E-23 T 28-03-2018 IPR028995 Glycoside hydrolase families 57/38, central domain CFK41_RS11435 a97071e6b538a79554297a5d444bce1d 1033 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 656 1030 1.9E-35 T 28-03-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 CFK41_RS11435 a97071e6b538a79554297a5d444bce1d 1033 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 252 507 2.9E-79 T 28-03-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 CFK41_RS11435 a97071e6b538a79554297a5d444bce1d 1033 SUPERFAMILY SSF74650 658 1030 6.28E-41 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CFK41_RS12375 f77b8bf771d0910c8238881fc2def64a 389 Pfam PF08442 ATP-grasp domain 2 195 5.4E-68 T 28-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CFK41_RS12375 f77b8bf771d0910c8238881fc2def64a 389 Gene3D G3DSA:3.30.1490.20 21 88 4.3E-23 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CFK41_RS12375 f77b8bf771d0910c8238881fc2def64a 389 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 250 274 - T 28-03-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CFK41_RS12375 f77b8bf771d0910c8238881fc2def64a 389 Gene3D G3DSA:3.40.50.261 233 385 5.9E-35 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CFK41_RS12375 f77b8bf771d0910c8238881fc2def64a 389 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 2 385 1.7E-125 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CFK41_RS12375 f77b8bf771d0910c8238881fc2def64a 389 SUPERFAMILY SSF56059 3 230 5.95E-64 T 28-03-2018 CFK41_RS12375 f77b8bf771d0910c8238881fc2def64a 389 SUPERFAMILY SSF52210 232 384 3.4E-40 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CFK41_RS12375 f77b8bf771d0910c8238881fc2def64a 389 Gene3D G3DSA:3.30.470.20 89 232 3.1E-47 T 28-03-2018 CFK41_RS12375 f77b8bf771d0910c8238881fc2def64a 389 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 38.284 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CFK41_RS12375 f77b8bf771d0910c8238881fc2def64a 389 Pfam PF00549 CoA-ligase 257 368 2.1E-13 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CFK41_RS12375 f77b8bf771d0910c8238881fc2def64a 389 PIRSF PIRSF001554 1 388 5.8E-133 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CFK41_RS12580 8f9d843dd44031bc6a1219dc10a76754 145 Gene3D G3DSA:3.10.180.10 1 140 1.3E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS12580 8f9d843dd44031bc6a1219dc10a76754 145 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 125 2.6E-4 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CFK41_RS12580 8f9d843dd44031bc6a1219dc10a76754 145 SUPERFAMILY SSF54593 5 132 1.09E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS05340 7786ef71c599358165018f1c10193ac3 553 Gene3D G3DSA:3.40.50.300 360 553 2.3E-39 T 28-03-2018 CFK41_RS05340 7786ef71c599358165018f1c10193ac3 553 SUPERFAMILY SSF52540 369 551 1.92E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS05340 7786ef71c599358165018f1c10193ac3 553 Pfam PF00005 ABC transporter 21 195 1.9E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS05340 7786ef71c599358165018f1c10193ac3 553 Pfam PF00005 ABC transporter 375 503 2.7E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS05340 7786ef71c599358165018f1c10193ac3 553 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS05340 7786ef71c599358165018f1c10193ac3 553 Gene3D G3DSA:3.40.50.300 5 348 7.0E-45 T 28-03-2018 CFK41_RS05340 7786ef71c599358165018f1c10193ac3 553 SMART SM00382 382 549 8.7E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS05340 7786ef71c599358165018f1c10193ac3 553 SMART SM00382 29 240 8.9E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS05340 7786ef71c599358165018f1c10193ac3 553 SUPERFAMILY SSF52540 5 85 3.52E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS05340 7786ef71c599358165018f1c10193ac3 553 SUPERFAMILY SSF52540 136 243 3.52E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS13360 178c73fc565cafa23d26fc48471328a6 337 Gene3D G3DSA:3.40.50.620 153 297 2.2E-22 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS13360 178c73fc565cafa23d26fc48471328a6 337 Pfam PF02698 DUF218 domain 164 308 2.8E-24 T 28-03-2018 IPR003848 Domain of unknown function DUF218 CFK41_RS13650 4ac39eef7c5ca7559bb87c5afebc9592 313 SUPERFAMILY SSF52283 18 122 1.87E-10 T 28-03-2018 CFK41_RS13650 4ac39eef7c5ca7559bb87c5afebc9592 313 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 100 283 1.6E-41 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CFK41_RS13650 4ac39eef7c5ca7559bb87c5afebc9592 313 Gene3D G3DSA:3.40.50.720 17 105 2.8E-14 T 28-03-2018 CFK41_RS13650 4ac39eef7c5ca7559bb87c5afebc9592 313 SUPERFAMILY SSF51735 92 284 2.54E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS13650 4ac39eef7c5ca7559bb87c5afebc9592 313 Gene3D G3DSA:3.40.50.720 106 284 4.9E-47 T 28-03-2018 CFK41_RS06765 d707fd73193c7abae1de24429b47f78f 269 SUPERFAMILY SSF46785 17 88 1.29E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS06765 d707fd73193c7abae1de24429b47f78f 269 SUPERFAMILY SSF55781 90 262 1.24E-43 T 28-03-2018 IPR029016 GAF domain-like CFK41_RS06765 d707fd73193c7abae1de24429b47f78f 269 SMART SM00346 17 106 2.1E-18 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CFK41_RS06765 d707fd73193c7abae1de24429b47f78f 269 Gene3D G3DSA:1.10.10.10 2 77 1.7E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS06765 d707fd73193c7abae1de24429b47f78f 269 Gene3D G3DSA:3.30.450.40 92 267 1.6E-47 T 28-03-2018 IPR029016 GAF domain-like CFK41_RS06765 d707fd73193c7abae1de24429b47f78f 269 Pfam PF01614 Bacterial transcriptional regulator 136 257 3.7E-32 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CFK41_RS06765 d707fd73193c7abae1de24429b47f78f 269 Pfam PF09339 IclR helix-turn-helix domain 19 67 3.9E-13 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CFK41_RS16000 343588496d094cddb7ef4b80161c032a 412 Gene3D G3DSA:3.30.565.10 281 412 3.6E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS16000 343588496d094cddb7ef4b80161c032a 412 SUPERFAMILY SSF55874 316 400 1.75E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS16000 343588496d094cddb7ef4b80161c032a 412 Pfam PF07730 Histidine kinase 214 279 7.1E-14 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CFK41_RS02370 8c42d7fc24f4975602b7e0e5349053d1 548 Gene3D G3DSA:3.40.190.10 220 548 5.6E-30 T 28-03-2018 CFK41_RS02370 8c42d7fc24f4975602b7e0e5349053d1 548 Pfam PF01547 Bacterial extracellular solute-binding protein 125 353 7.6E-16 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CFK41_RS02370 8c42d7fc24f4975602b7e0e5349053d1 548 SUPERFAMILY SSF53850 33 39 7.76E-58 T 28-03-2018 CFK41_RS02370 8c42d7fc24f4975602b7e0e5349053d1 548 SUPERFAMILY SSF53850 94 545 7.76E-58 T 28-03-2018 CFK41_RS10035 bfe73ec8f6fa0fbd492cc356d6a598fd 721 Gene3D G3DSA:3.20.20.80 138 580 3.9E-107 T 28-03-2018 CFK41_RS10035 bfe73ec8f6fa0fbd492cc356d6a598fd 721 SUPERFAMILY SSF81296 6 147 2.8E-44 T 28-03-2018 IPR014756 Immunoglobulin E-set CFK41_RS10035 bfe73ec8f6fa0fbd492cc356d6a598fd 721 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 10 96 2.8E-20 T 28-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 CFK41_RS10035 bfe73ec8f6fa0fbd492cc356d6a598fd 721 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 6 699 1.3E-298 T 28-03-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 CFK41_RS10035 bfe73ec8f6fa0fbd492cc356d6a598fd 721 SUPERFAMILY SSF51445 500 576 5.58E-130 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS10035 bfe73ec8f6fa0fbd492cc356d6a598fd 721 SUPERFAMILY SSF51445 133 471 5.58E-130 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS10035 bfe73ec8f6fa0fbd492cc356d6a598fd 721 Pfam PF00128 Alpha amylase, catalytic domain 189 530 6.6E-12 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CFK41_RS10035 bfe73ec8f6fa0fbd492cc356d6a598fd 721 Gene3D G3DSA:2.60.40.1180 581 702 6.9E-28 T 28-03-2018 CFK41_RS10035 bfe73ec8f6fa0fbd492cc356d6a598fd 721 Gene3D G3DSA:2.60.40.10 5 136 1.8E-51 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS10035 bfe73ec8f6fa0fbd492cc356d6a598fd 721 SUPERFAMILY SSF51011 592 699 7.55E-24 T 28-03-2018 CFK41_RS10035 bfe73ec8f6fa0fbd492cc356d6a598fd 721 SMART SM00642 177 568 2.6E-8 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CFK41_RS10160 fe57f27960bd5295e1eed12d8b07b430 168 SMART SM00347 49 149 2.8E-24 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS10160 fe57f27960bd5295e1eed12d8b07b430 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 105 2.3E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS10160 fe57f27960bd5295e1eed12d8b07b430 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 109 125 2.3E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS10160 fe57f27960bd5295e1eed12d8b07b430 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 139 159 2.3E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS10160 fe57f27960bd5295e1eed12d8b07b430 168 Gene3D G3DSA:1.10.10.10 43 130 1.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS10160 fe57f27960bd5295e1eed12d8b07b430 168 Pfam PF01047 MarR family 57 114 6.2E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS10160 fe57f27960bd5295e1eed12d8b07b430 168 Gene3D G3DSA:1.10.287.100 131 163 1.6E-5 T 28-03-2018 CFK41_RS10160 fe57f27960bd5295e1eed12d8b07b430 168 SUPERFAMILY SSF46785 31 163 3.11E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS02800 ea022f549f6ebd185375109f81a0d96d 215 Pfam PF02581 Thiamine monophosphate synthase 8 195 2.4E-48 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CFK41_RS02800 ea022f549f6ebd185375109f81a0d96d 215 Gene3D G3DSA:3.20.20.70 1 210 1.1E-32 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS02800 ea022f549f6ebd185375109f81a0d96d 215 SUPERFAMILY SSF51391 4 209 6.02E-47 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CFK41_RS02800 ea022f549f6ebd185375109f81a0d96d 215 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 6 213 23.193 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CFK41_RS17030 985d4ccca4dbe0ccb3e38dc2c97272a0 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 68 8.4E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS17030 985d4ccca4dbe0ccb3e38dc2c97272a0 237 SMART SM00345 10 68 0.003 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS17030 985d4ccca4dbe0ccb3e38dc2c97272a0 237 Gene3D G3DSA:1.10.10.10 3 81 1.9E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS17030 985d4ccca4dbe0ccb3e38dc2c97272a0 237 SUPERFAMILY SSF48008 93 228 7.59E-20 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS17030 985d4ccca4dbe0ccb3e38dc2c97272a0 237 Gene3D G3DSA:1.20.120.530 90 231 4.0E-21 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS17030 985d4ccca4dbe0ccb3e38dc2c97272a0 237 SMART SM00895 97 223 1.3E-12 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS17030 985d4ccca4dbe0ccb3e38dc2c97272a0 237 SUPERFAMILY SSF46785 6 72 1.07E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS17030 985d4ccca4dbe0ccb3e38dc2c97272a0 237 Pfam PF07729 FCD domain 98 219 1.2E-17 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS14145 c8c23c6a1ce74a01a8db3f12de836078 170 ProSitePatterns PS00818 Dps protein family signature 1. 47 63 - T 28-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 CFK41_RS14145 c8c23c6a1ce74a01a8db3f12de836078 170 SUPERFAMILY SSF47240 23 162 7.67E-44 T 28-03-2018 IPR009078 Ferritin-like superfamily CFK41_RS14145 c8c23c6a1ce74a01a8db3f12de836078 170 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 47 63 2.7E-10 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CFK41_RS14145 c8c23c6a1ce74a01a8db3f12de836078 170 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 71 87 2.7E-10 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CFK41_RS14145 c8c23c6a1ce74a01a8db3f12de836078 170 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 142 160 2.7E-10 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CFK41_RS14145 c8c23c6a1ce74a01a8db3f12de836078 170 Gene3D G3DSA:1.20.1260.10 2 169 1.7E-37 T 28-03-2018 IPR012347 Ferritin-related CFK41_RS14145 c8c23c6a1ce74a01a8db3f12de836078 170 PIRSF PIRSF005900 7 169 6.8E-40 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CFK41_RS14145 c8c23c6a1ce74a01a8db3f12de836078 170 Pfam PF00210 Ferritin-like domain 27 163 8.9E-21 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CFK41_RS16845 5c3adf4630ab9f4c78d80888dbfcfc81 921 Gene3D G3DSA:2.60.40.10 477 571 0.043 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS16845 5c3adf4630ab9f4c78d80888dbfcfc81 921 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 20 40 0.0011 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CFK41_RS16845 5c3adf4630ab9f4c78d80888dbfcfc81 921 Gene3D G3DSA:2.60.40.1190 591 788 9.5E-26 T 28-03-2018 CFK41_RS16845 5c3adf4630ab9f4c78d80888dbfcfc81 921 SUPERFAMILY SSF49344 607 787 6.28E-22 T 28-03-2018 CFK41_RS16845 5c3adf4630ab9f4c78d80888dbfcfc81 921 Gene3D G3DSA:2.60.40.10 339 438 2.0E-9 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS16845 5c3adf4630ab9f4c78d80888dbfcfc81 921 Pfam PF02585 GlcNAc-PI de-N-acetylase 63 200 1.5E-18 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CFK41_RS16845 5c3adf4630ab9f4c78d80888dbfcfc81 921 Gene3D G3DSA:3.40.50.10320 51 314 3.8E-31 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CFK41_RS16845 5c3adf4630ab9f4c78d80888dbfcfc81 921 SUPERFAMILY SSF102588 60 286 7.72E-29 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CFK41_RS16845 5c3adf4630ab9f4c78d80888dbfcfc81 921 Pfam PF06452 Carbohydrate family 9 binding domain-like 603 788 7.3E-20 T 28-03-2018 IPR010502 Carbohydrate-binding domain, family 9 GO:0004553|GO:0016052|GO:0030246 MetaCyc: PWY-6784 CFK41_RS16845 5c3adf4630ab9f4c78d80888dbfcfc81 921 ProDom PD004647 DEGRADATION HYDROLASE GLYCOSIDASE XYLAN A XYLANASE PRECURSOR SIGNAL REPEAT 14- 608 787 0.01 T 28-03-2018 CFK41_RS16845 5c3adf4630ab9f4c78d80888dbfcfc81 921 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 354 423 2.1E-6 T 28-03-2018 IPR018905 Alpha-galactosidase, NEW3 domain CFK41_RS04905 1e7f5855b4bf2722dd29c463ff5ae522 318 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 11 317 2.5E-123 T 28-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CFK41_RS04905 1e7f5855b4bf2722dd29c463ff5ae522 318 PIRSF PIRSF000545 2 318 1.1E-137 T 28-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CFK41_RS04905 1e7f5855b4bf2722dd29c463ff5ae522 318 Gene3D G3DSA:3.40.50.300 10 317 8.8E-60 T 28-03-2018 CFK41_RS04905 1e7f5855b4bf2722dd29c463ff5ae522 318 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 91 235 3.3E-12 T 28-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 CFK41_RS04905 1e7f5855b4bf2722dd29c463ff5ae522 318 Hamap MF_00215 Pantothenate kinase [coaA]. 1 318 168.388 T 28-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CFK41_RS04905 1e7f5855b4bf2722dd29c463ff5ae522 318 SUPERFAMILY SSF52540 10 317 1.95E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS14160 0257b4208d4f0c4b815da3c97c199ff7 414 SUPERFAMILY SSF54826 1 124 3.7E-21 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS14160 0257b4208d4f0c4b815da3c97c199ff7 414 SMART SM00922 162 256 7.5E-20 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CFK41_RS14160 0257b4208d4f0c4b815da3c97c199ff7 414 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 33 124 3.0E-6 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CFK41_RS14160 0257b4208d4f0c4b815da3c97c199ff7 414 Gene3D G3DSA:3.30.390.10 1 131 3.9E-31 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS14160 0257b4208d4f0c4b815da3c97c199ff7 414 Pfam PF13378 Enolase C-terminal domain-like 165 377 1.9E-47 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS14160 0257b4208d4f0c4b815da3c97c199ff7 414 Gene3D G3DSA:3.20.20.120 132 386 2.9E-55 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS14160 0257b4208d4f0c4b815da3c97c199ff7 414 SUPERFAMILY SSF51604 124 384 1.17E-68 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS09840 bd56181313711d5ac98aa4b030a6f52d 360 Gene3D G3DSA:3.40.1030.10 75 360 4.9E-88 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CFK41_RS09840 bd56181313711d5ac98aa4b030a6f52d 360 SUPERFAMILY SSF47648 8 75 1.15E-14 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CFK41_RS09840 bd56181313711d5ac98aa4b030a6f52d 360 Pfam PF02885 Glycosyl transferase family, helical bundle domain 11 71 1.2E-15 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CFK41_RS09840 bd56181313711d5ac98aa4b030a6f52d 360 SUPERFAMILY SSF52418 79 353 4.19E-68 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CFK41_RS09840 bd56181313711d5ac98aa4b030a6f52d 360 Gene3D G3DSA:1.20.970.10 2 74 1.6E-18 T 28-03-2018 CFK41_RS09840 bd56181313711d5ac98aa4b030a6f52d 360 Pfam PF00591 Glycosyl transferase family, a/b domain 79 315 1.0E-72 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CFK41_RS09840 bd56181313711d5ac98aa4b030a6f52d 360 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 14 349 4.3E-97 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CFK41_RS09840 bd56181313711d5ac98aa4b030a6f52d 360 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 10 351 31.361 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CFK41_RS01590 0be7eae3fcf91552dd42017d606e6b25 513 SMART SM00382 293 488 0.0029 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS01590 0be7eae3fcf91552dd42017d606e6b25 513 SMART SM00382 30 220 3.8E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS01590 0be7eae3fcf91552dd42017d606e6b25 513 Gene3D G3DSA:3.40.50.300 3 233 1.3E-51 T 28-03-2018 CFK41_RS01590 0be7eae3fcf91552dd42017d606e6b25 513 SUPERFAMILY SSF52540 265 499 9.63E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS01590 0be7eae3fcf91552dd42017d606e6b25 513 SUPERFAMILY SSF52540 4 226 3.77E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS01590 0be7eae3fcf91552dd42017d606e6b25 513 Gene3D G3DSA:3.40.50.300 265 512 5.0E-35 T 28-03-2018 CFK41_RS01590 0be7eae3fcf91552dd42017d606e6b25 513 ProSitePatterns PS00211 ABC transporters family signature. 413 427 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS01590 0be7eae3fcf91552dd42017d606e6b25 513 Pfam PF00005 ABC transporter 285 440 6.1E-17 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS01590 0be7eae3fcf91552dd42017d606e6b25 513 Pfam PF00005 ABC transporter 21 172 8.8E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS12135 c5dfd67cf99c65fa5782ae3ccf82b372 115 Gene3D G3DSA:1.20.59.10 16 114 8.6E-24 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CFK41_RS12135 c5dfd67cf99c65fa5782ae3ccf82b372 115 Pfam PF01817 Chorismate mutase type II 27 102 7.3E-18 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CFK41_RS12135 c5dfd67cf99c65fa5782ae3ccf82b372 115 SUPERFAMILY SSF48600 30 110 3.05E-24 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CFK41_RS12135 c5dfd67cf99c65fa5782ae3ccf82b372 115 TIGRFAM TIGR01795 CM_mono_cladeE: chorismate mutase 23 109 1.4E-40 T 28-03-2018 IPR010951 Chorismate mutase, bacteria CFK41_RS12135 c5dfd67cf99c65fa5782ae3ccf82b372 115 SMART SM00830 27 107 5.0E-25 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CFK41_RS15705 efeaa5634f80c8cae763f985b81778d1 169 SUPERFAMILY SSF109854 2 162 7.06E-20 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CFK41_RS15705 efeaa5634f80c8cae763f985b81778d1 169 Gene3D G3DSA:1.20.120.450 1 165 5.2E-23 T 28-03-2018 CFK41_RS15705 efeaa5634f80c8cae763f985b81778d1 169 Pfam PF04978 Protein of unknown function (DUF664) 7 161 1.9E-7 T 28-03-2018 IPR007061 Protein of unknown function DUF664 CFK41_RS08630 9038194ff1dc667625387bed0f4abacd 269 SUPERFAMILY SSF159659 4 247 8.11E-70 T 28-03-2018 CFK41_RS08630 9038194ff1dc667625387bed0f4abacd 269 Gene3D G3DSA:1.10.287.100 205 244 5.5E-4 T 28-03-2018 CFK41_RS08630 9038194ff1dc667625387bed0f4abacd 269 PIRSF PIRSF028754 2 269 4.9E-83 T 28-03-2018 IPR008492 Protein of unknown function DUF774 CFK41_RS08630 9038194ff1dc667625387bed0f4abacd 269 Pfam PF09754 PAC2 family 9 224 7.4E-40 T 28-03-2018 IPR019151 Proteasome assembly chaperone 2 CFK41_RS00480 7a36cf9979fa9ded6ab37a331c7ffac2 334 Gene3D G3DSA:3.40.50.620 175 321 3.4E-26 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS00480 7a36cf9979fa9ded6ab37a331c7ffac2 334 SUPERFAMILY SSF52402 23 161 1.0E-29 T 28-03-2018 CFK41_RS00480 7a36cf9979fa9ded6ab37a331c7ffac2 334 Pfam PF00582 Universal stress protein family 23 158 5.2E-24 T 28-03-2018 IPR006016 UspA GO:0006950 CFK41_RS00480 7a36cf9979fa9ded6ab37a331c7ffac2 334 Pfam PF00582 Universal stress protein family 181 319 2.3E-20 T 28-03-2018 IPR006016 UspA GO:0006950 CFK41_RS00480 7a36cf9979fa9ded6ab37a331c7ffac2 334 PRINTS PR01438 Universal stress protein signature 20 38 9.2E-12 T 28-03-2018 IPR006015 Universal stress protein A CFK41_RS00480 7a36cf9979fa9ded6ab37a331c7ffac2 334 PRINTS PR01438 Universal stress protein signature 118 130 9.2E-12 T 28-03-2018 IPR006015 Universal stress protein A CFK41_RS00480 7a36cf9979fa9ded6ab37a331c7ffac2 334 PRINTS PR01438 Universal stress protein signature 136 158 9.2E-12 T 28-03-2018 IPR006015 Universal stress protein A CFK41_RS00480 7a36cf9979fa9ded6ab37a331c7ffac2 334 SUPERFAMILY SSF52402 180 320 6.03E-26 T 28-03-2018 CFK41_RS00480 7a36cf9979fa9ded6ab37a331c7ffac2 334 Gene3D G3DSA:3.40.50.620 10 164 3.1E-31 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS10865 a3560905467628df078298e084659e4a 622 SUPERFAMILY SSF53067 163 358 5.53E-61 T 28-03-2018 CFK41_RS10865 a3560905467628df078298e084659e4a 622 Gene3D G3DSA:3.30.420.40 173 337 6.7E-42 T 28-03-2018 CFK41_RS10865 a3560905467628df078298e084659e4a 622 SUPERFAMILY SSF100934 511 589 6.28E-9 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CFK41_RS10865 a3560905467628df078298e084659e4a 622 PRINTS PR00301 70kDa heat shock protein signature 31 43 6.1E-74 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CFK41_RS10865 a3560905467628df078298e084659e4a 622 PRINTS PR00301 70kDa heat shock protein signature 310 326 6.1E-74 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CFK41_RS10865 a3560905467628df078298e084659e4a 622 PRINTS PR00301 70kDa heat shock protein signature 174 184 6.1E-74 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CFK41_RS10865 a3560905467628df078298e084659e4a 622 PRINTS PR00301 70kDa heat shock protein signature 3 16 6.1E-74 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CFK41_RS10865 a3560905467628df078298e084659e4a 622 PRINTS PR00301 70kDa heat shock protein signature 365 384 6.1E-74 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CFK41_RS10865 a3560905467628df078298e084659e4a 622 PRINTS PR00301 70kDa heat shock protein signature 446 462 6.1E-74 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CFK41_RS10865 a3560905467628df078298e084659e4a 622 PRINTS PR00301 70kDa heat shock protein signature 114 134 6.1E-74 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CFK41_RS10865 a3560905467628df078298e084659e4a 622 PRINTS PR00301 70kDa heat shock protein signature 54 62 6.1E-74 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CFK41_RS10865 a3560905467628df078298e084659e4a 622 PRINTS PR00301 70kDa heat shock protein signature 342 362 6.1E-74 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CFK41_RS10865 a3560905467628df078298e084659e4a 622 Gene3D G3DSA:2.60.34.10 362 492 7.9E-62 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CFK41_RS10865 a3560905467628df078298e084659e4a 622 Pfam PF00012 Hsp70 protein 81 582 2.0E-203 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CFK41_RS10865 a3560905467628df078298e084659e4a 622 Pfam PF00012 Hsp70 protein 4 80 1.9E-30 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CFK41_RS10865 a3560905467628df078298e084659e4a 622 SUPERFAMILY SSF53067 1 159 8.91E-58 T 28-03-2018 CFK41_RS10865 a3560905467628df078298e084659e4a 622 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 617 35.179 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CFK41_RS10865 a3560905467628df078298e084659e4a 622 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CFK41_RS10865 a3560905467628df078298e084659e4a 622 Gene3D G3DSA:1.20.1270.10 493 592 6.0E-25 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CFK41_RS10865 a3560905467628df078298e084659e4a 622 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 168 181 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CFK41_RS10865 a3560905467628df078298e084659e4a 622 SUPERFAMILY SSF100920 361 517 1.03E-57 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CFK41_RS10865 a3560905467628df078298e084659e4a 622 Gene3D G3DSA:3.30.420.40 1 172 5.0E-67 T 28-03-2018 CFK41_RS10865 a3560905467628df078298e084659e4a 622 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 313 327 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CFK41_RS10865 a3560905467628df078298e084659e4a 622 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 582 2.8E-265 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CFK41_RS09480 94db0693ffd985bec891710b4724b336 512 Pfam PF00425 chorismate binding enzyme 237 495 9.0E-95 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CFK41_RS09480 94db0693ffd985bec891710b4724b336 512 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 38 503 2.3E-159 T 28-03-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CFK41_RS09480 94db0693ffd985bec891710b4724b336 512 SUPERFAMILY SSF56322 27 502 9.55E-141 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CFK41_RS09480 94db0693ffd985bec891710b4724b336 512 Gene3D G3DSA:3.60.120.10 27 507 4.2E-154 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CFK41_RS09480 94db0693ffd985bec891710b4724b336 512 PRINTS PR00095 Anthranilate synthase component I signature 437 451 1.5E-22 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CFK41_RS09480 94db0693ffd985bec891710b4724b336 512 PRINTS PR00095 Anthranilate synthase component I signature 452 466 1.5E-22 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CFK41_RS09480 94db0693ffd985bec891710b4724b336 512 PRINTS PR00095 Anthranilate synthase component I signature 357 370 1.5E-22 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CFK41_RS09480 94db0693ffd985bec891710b4724b336 512 PRINTS PR00095 Anthranilate synthase component I signature 343 356 1.5E-22 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CFK41_RS09480 94db0693ffd985bec891710b4724b336 512 Pfam PF04715 Anthranilate synthase component I, N terminal region 38 179 2.2E-30 T 28-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CFK41_RS12165 edb1d3b1757a3e4521637a42aa349020 512 SUPERFAMILY SSF102735 3 136 6.93E-34 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CFK41_RS12165 edb1d3b1757a3e4521637a42aa349020 512 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 163 217 1.5E-4 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain CFK41_RS12165 edb1d3b1757a3e4521637a42aa349020 512 Hamap MF_00303 Trigger factor [tig]. 1 412 17.819 T 28-03-2018 IPR005215 Trigger factor GO:0015031 CFK41_RS12165 edb1d3b1757a3e4521637a42aa349020 512 TIGRFAM TIGR00115 tig: trigger factor 12 403 6.8E-102 T 28-03-2018 IPR005215 Trigger factor GO:0015031 CFK41_RS12165 edb1d3b1757a3e4521637a42aa349020 512 Gene3D G3DSA:3.10.50.40 158 225 1.9E-6 T 28-03-2018 CFK41_RS12165 edb1d3b1757a3e4521637a42aa349020 512 Pfam PF05697 Bacterial trigger factor protein (TF) 2 149 4.0E-37 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CFK41_RS12165 edb1d3b1757a3e4521637a42aa349020 512 SUPERFAMILY SSF54534 138 247 1.22E-16 T 28-03-2018 CFK41_RS12165 edb1d3b1757a3e4521637a42aa349020 512 SUPERFAMILY SSF109998 249 415 1.57E-32 T 28-03-2018 IPR027304 Trigger factor/SurA domain CFK41_RS12165 edb1d3b1757a3e4521637a42aa349020 512 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 261 404 1.5E-20 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CFK41_RS12165 edb1d3b1757a3e4521637a42aa349020 512 Gene3D G3DSA:3.30.70.1050 1 124 1.4E-32 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CFK41_RS12165 edb1d3b1757a3e4521637a42aa349020 512 Gene3D G3DSA:1.10.3120.10 226 381 6.6E-32 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CFK41_RS15160 44bde9fc05d05e525b8101a2a91e6f0d 508 Pfam PF00450 Serine carboxypeptidase 84 461 3.4E-10 T 28-03-2018 IPR001563 Peptidase S10, serine carboxypeptidase GO:0004185|GO:0006508 CFK41_RS15160 44bde9fc05d05e525b8101a2a91e6f0d 508 Gene3D G3DSA:3.40.50.1820 22 479 1.1E-50 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS15160 44bde9fc05d05e525b8101a2a91e6f0d 508 SUPERFAMILY SSF53474 37 495 5.08E-63 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS01230 43c2469ff6aa1dbed3d0f7ffff3f2882 547 SUPERFAMILY SSF53850 32 536 4.89E-112 T 28-03-2018 CFK41_RS01230 43c2469ff6aa1dbed3d0f7ffff3f2882 547 PIRSF PIRSF002741 2 527 1.4E-78 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CFK41_RS01230 43c2469ff6aa1dbed3d0f7ffff3f2882 547 Gene3D G3DSA:3.40.190.10 163 299 2.5E-31 T 28-03-2018 CFK41_RS01230 43c2469ff6aa1dbed3d0f7ffff3f2882 547 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 442 2.2E-69 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CFK41_RS01230 43c2469ff6aa1dbed3d0f7ffff3f2882 547 Gene3D G3DSA:3.10.105.10 300 510 1.5E-40 T 28-03-2018 CFK41_RS01230 43c2469ff6aa1dbed3d0f7ffff3f2882 547 Gene3D G3DSA:3.90.76.10 54 162 1.6E-28 T 28-03-2018 CFK41_RS06885 c54021d6cedb61a8bac4e0f9377a270e 441 SUPERFAMILY SSF55205 14 430 2.75E-99 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CFK41_RS06885 c54021d6cedb61a8bac4e0f9377a270e 441 ProSitePatterns PS00885 EPSP synthase signature 2. 347 365 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CFK41_RS06885 c54021d6cedb61a8bac4e0f9377a270e 441 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 14 434 27.471 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CFK41_RS06885 c54021d6cedb61a8bac4e0f9377a270e 441 Gene3D G3DSA:3.65.10.10 240 432 1.1E-47 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CFK41_RS06885 c54021d6cedb61a8bac4e0f9377a270e 441 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 20 432 1.2E-108 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CFK41_RS06885 c54021d6cedb61a8bac4e0f9377a270e 441 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 15 426 1.1E-100 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CFK41_RS06885 c54021d6cedb61a8bac4e0f9377a270e 441 Gene3D G3DSA:3.65.10.10 26 239 7.7E-51 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CFK41_RS06885 c54021d6cedb61a8bac4e0f9377a270e 441 PIRSF PIRSF000505 4 434 3.2E-112 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CFK41_RS04305 76cbe0fbb4ee5f9a17549f1947f3ec20 584 SUPERFAMILY SSF52540 47 269 6.35E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS04305 76cbe0fbb4ee5f9a17549f1947f3ec20 584 Pfam PF00350 Dynamin family 59 197 1.1E-10 T 28-03-2018 IPR022812 Dynamin superfamily CFK41_RS04305 76cbe0fbb4ee5f9a17549f1947f3ec20 584 Gene3D G3DSA:3.40.50.300 2 583 7.8E-24 T 28-03-2018 CFK41_RS10175 a281f458680020e811992a276c184be3 457 Gene3D G3DSA:3.40.50.720 161 404 5.7E-22 T 28-03-2018 CFK41_RS10175 a281f458680020e811992a276c184be3 457 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 346 1.2E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS10175 a281f458680020e811992a276c184be3 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 7.3E-7 T 28-03-2018 CFK41_RS10175 a281f458680020e811992a276c184be3 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 167 185 7.3E-7 T 28-03-2018 CFK41_RS10175 a281f458680020e811992a276c184be3 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 7.3E-7 T 28-03-2018 CFK41_RS10175 a281f458680020e811992a276c184be3 457 Gene3D G3DSA:3.50.50.60 9 160 8.5E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS10175 a281f458680020e811992a276c184be3 457 SUPERFAMILY SSF51905 165 360 2.94E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS10175 a281f458680020e811992a276c184be3 457 SUPERFAMILY SSF51905 9 189 1.19E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS15025 d4a007f49df3f52557abb6158656da56 340 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 57 71 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CFK41_RS15025 d4a007f49df3f52557abb6158656da56 340 Pfam PF00107 Zinc-binding dehydrogenase 175 301 2.2E-22 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CFK41_RS15025 d4a007f49df3f52557abb6158656da56 340 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 122 5.5E-23 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CFK41_RS15025 d4a007f49df3f52557abb6158656da56 340 Gene3D G3DSA:3.90.180.10 1 159 2.4E-38 T 28-03-2018 CFK41_RS15025 d4a007f49df3f52557abb6158656da56 340 Gene3D G3DSA:3.40.50.10730 160 277 1.4E-23 T 28-03-2018 CFK41_RS15025 d4a007f49df3f52557abb6158656da56 340 SUPERFAMILY SSF51735 146 306 3.73E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS15025 d4a007f49df3f52557abb6158656da56 340 SUPERFAMILY SSF50129 1 165 6.7E-45 T 28-03-2018 IPR011032 GroES-like CFK41_RS09430 3a25f768a71a22b8ac8e57f65041b244 489 SUPERFAMILY SSF52935 320 468 3.92E-37 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CFK41_RS09430 3a25f768a71a22b8ac8e57f65041b244 489 Gene3D G3DSA:3.20.20.60 1 83 6.0E-18 T 28-03-2018 CFK41_RS09430 3a25f768a71a22b8ac8e57f65041b244 489 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 467 1.5E-164 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CFK41_RS09430 3a25f768a71a22b8ac8e57f65041b244 489 Gene3D G3DSA:2.40.33.10 84 157 2.3E-27 T 28-03-2018 CFK41_RS09430 3a25f768a71a22b8ac8e57f65041b244 489 SUPERFAMILY SSF51621 165 334 3.49E-97 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CFK41_RS09430 3a25f768a71a22b8ac8e57f65041b244 489 SUPERFAMILY SSF51621 1 75 3.49E-97 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CFK41_RS09430 3a25f768a71a22b8ac8e57f65041b244 489 PRINTS PR01050 Pyruvate kinase family signature 310 326 4.3E-64 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CFK41_RS09430 3a25f768a71a22b8ac8e57f65041b244 489 PRINTS PR01050 Pyruvate kinase family signature 184 198 4.3E-64 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CFK41_RS09430 3a25f768a71a22b8ac8e57f65041b244 489 PRINTS PR01050 Pyruvate kinase family signature 266 290 4.3E-64 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CFK41_RS09430 3a25f768a71a22b8ac8e57f65041b244 489 PRINTS PR01050 Pyruvate kinase family signature 214 240 4.3E-64 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CFK41_RS09430 3a25f768a71a22b8ac8e57f65041b244 489 PRINTS PR01050 Pyruvate kinase family signature 291 309 4.3E-64 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CFK41_RS09430 3a25f768a71a22b8ac8e57f65041b244 489 PRINTS PR01050 Pyruvate kinase family signature 59 75 4.3E-64 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CFK41_RS09430 3a25f768a71a22b8ac8e57f65041b244 489 PRINTS PR01050 Pyruvate kinase family signature 241 265 4.3E-64 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CFK41_RS09430 3a25f768a71a22b8ac8e57f65041b244 489 Gene3D G3DSA:3.20.20.60 158 318 1.3E-60 T 28-03-2018 CFK41_RS09430 3a25f768a71a22b8ac8e57f65041b244 489 SUPERFAMILY SSF50800 70 164 1.55E-26 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain CFK41_RS09430 3a25f768a71a22b8ac8e57f65041b244 489 ProSitePatterns PS00110 Pyruvate kinase active site signature. 212 224 - T 28-03-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CFK41_RS09430 3a25f768a71a22b8ac8e57f65041b244 489 Pfam PF02887 Pyruvate kinase, alpha/beta domain 353 465 4.7E-28 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CFK41_RS09430 3a25f768a71a22b8ac8e57f65041b244 489 Gene3D G3DSA:3.40.1380.20 319 468 4.1E-46 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CFK41_RS09430 3a25f768a71a22b8ac8e57f65041b244 489 Pfam PF00224 Pyruvate kinase, barrel domain 1 334 6.5E-125 T 28-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CFK41_RS09500 f9366308f3ef8026f53481478b917725 120 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 11 80 2.7E-21 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS09500 f9366308f3ef8026f53481478b917725 120 SUPERFAMILY SSF63562 11 94 6.54E-24 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CFK41_RS09500 f9366308f3ef8026f53481478b917725 120 SMART SM01409 18 82 3.9E-14 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CFK41_RS09500 f9366308f3ef8026f53481478b917725 120 Pfam PF01192 RNA polymerase Rpb6 18 82 2.7E-14 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CFK41_RS09500 f9366308f3ef8026f53481478b917725 120 Gene3D G3DSA:3.90.940.10 12 102 1.3E-22 T 28-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CFK41_RS09500 f9366308f3ef8026f53481478b917725 120 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 11 83 14.46 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS08745 bff3cf4d917425e2eeb83d76e56f3219 970 SMART SM01142 802 969 1.4E-48 T 28-03-2018 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal CFK41_RS08745 bff3cf4d917425e2eeb83d76e56f3219 970 SMART SM00490 391 480 1.5E-10 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS08745 bff3cf4d917425e2eeb83d76e56f3219 970 Pfam PF08148 DSHCT (NUC185) domain 806 964 1.4E-29 T 28-03-2018 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal CFK41_RS08745 bff3cf4d917425e2eeb83d76e56f3219 970 Pfam PF00270 DEAD/DEAH box helicase 37 184 6.3E-17 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CFK41_RS08745 bff3cf4d917425e2eeb83d76e56f3219 970 SUPERFAMILY SSF52540 337 358 3.6E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS08745 bff3cf4d917425e2eeb83d76e56f3219 970 SUPERFAMILY SSF52540 400 493 3.6E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS08745 bff3cf4d917425e2eeb83d76e56f3219 970 SUPERFAMILY SSF52540 45 186 3.6E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS08745 bff3cf4d917425e2eeb83d76e56f3219 970 SMART SM00487 31 217 6.7E-32 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CFK41_RS08745 bff3cf4d917425e2eeb83d76e56f3219 970 Gene3D G3DSA:3.40.50.300 320 857 1.5E-16 T 28-03-2018 CFK41_RS08745 bff3cf4d917425e2eeb83d76e56f3219 970 Gene3D G3DSA:3.40.50.300 4 207 1.3E-36 T 28-03-2018 CFK41_RS05730 a364b50d6e9b8a3e1a813b7c5efc3ed3 368 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 22 364 42.903 T 28-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 CFK41_RS05730 a364b50d6e9b8a3e1a813b7c5efc3ed3 368 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 34 101 1.7E-14 T 28-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CFK41_RS05730 a364b50d6e9b8a3e1a813b7c5efc3ed3 368 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 54 360 1.8E-83 T 28-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CFK41_RS05730 a364b50d6e9b8a3e1a813b7c5efc3ed3 368 Gene3D G3DSA:3.30.930.10 21 368 4.2E-77 T 28-03-2018 CFK41_RS05730 a364b50d6e9b8a3e1a813b7c5efc3ed3 368 SUPERFAMILY SSF55681 106 365 7.3E-72 T 28-03-2018 CFK41_RS05730 a364b50d6e9b8a3e1a813b7c5efc3ed3 368 Pfam PF01409 tRNA synthetases class II core domain (F) 106 363 1.9E-91 T 28-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 CFK41_RS05730 a364b50d6e9b8a3e1a813b7c5efc3ed3 368 SUPERFAMILY SSF46589 26 112 4.24E-15 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CFK41_RS06145 e8a66d8bc64a8c3e0598d7db7419b873 186 Pfam PF00731 AIR carboxylase 24 163 7.2E-61 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CFK41_RS06145 e8a66d8bc64a8c3e0598d7db7419b873 186 Gene3D G3DSA:3.40.50.7700 14 184 3.5E-67 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CFK41_RS06145 e8a66d8bc64a8c3e0598d7db7419b873 186 SUPERFAMILY SSF52255 22 171 8.37E-60 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CFK41_RS06145 e8a66d8bc64a8c3e0598d7db7419b873 186 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 24 168 3.9E-58 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CFK41_RS06145 e8a66d8bc64a8c3e0598d7db7419b873 186 PIRSF PIRSF001338 19 186 1.6E-62 T 28-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 CFK41_RS06145 e8a66d8bc64a8c3e0598d7db7419b873 186 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 24 175 30.21 T 28-03-2018 IPR033747 Class I PurE CFK41_RS06145 e8a66d8bc64a8c3e0598d7db7419b873 186 SMART SM01001 22 171 8.7E-84 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CFK41_RS14780 2c55fa5350e5192e67945c80417531f1 409 Pfam PF07690 Major Facilitator Superfamily 28 204 4.0E-20 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS14780 2c55fa5350e5192e67945c80417531f1 409 Pfam PF07690 Major Facilitator Superfamily 225 387 1.5E-11 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS14780 2c55fa5350e5192e67945c80417531f1 409 Gene3D G3DSA:1.20.1250.20 9 203 4.4E-22 T 28-03-2018 CFK41_RS14780 2c55fa5350e5192e67945c80417531f1 409 Gene3D G3DSA:1.20.1250.20 206 389 2.7E-16 T 28-03-2018 CFK41_RS14780 2c55fa5350e5192e67945c80417531f1 409 SUPERFAMILY SSF103473 7 388 1.01E-44 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS08755 aa194be47d78499cf4e635e6b68ff37f 548 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 26 518 14.99 T 28-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 CFK41_RS08755 aa194be47d78499cf4e635e6b68ff37f 548 SUPERFAMILY SSF56317 240 510 4.32E-38 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CFK41_RS08755 aa194be47d78499cf4e635e6b68ff37f 548 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 79 480 3.3E-64 T 28-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 CFK41_RS08755 aa194be47d78499cf4e635e6b68ff37f 548 Pfam PF00795 Carbon-nitrogen hydrolase 268 499 1.4E-20 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CFK41_RS08755 aa194be47d78499cf4e635e6b68ff37f 548 Gene3D G3DSA:3.60.110.10 236 503 2.4E-37 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CFK41_RS13970 68030c5d8788d4eecbfc7c4c7bb07ed2 135 Pfam PF00583 Acetyltransferase (GNAT) family 42 109 1.1E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS13970 68030c5d8788d4eecbfc7c4c7bb07ed2 135 SUPERFAMILY SSF55729 19 121 9.12E-16 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS13970 68030c5d8788d4eecbfc7c4c7bb07ed2 135 Gene3D G3DSA:3.40.630.30 11 122 3.5E-16 T 28-03-2018 CFK41_RS17270 b2f9ecd4fdd1d4fcf96456906632f859 474 PIRSF PIRSF006060 1 465 3.9E-46 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CFK41_RS17270 b2f9ecd4fdd1d4fcf96456906632f859 474 Pfam PF13520 Amino acid permease 14 396 4.2E-26 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CFK41_RS09345 9d0b0fc84ec107f8451554c843835c75 905 Gene3D G3DSA:1.20.1060.10 445 629 5.2E-28 T 28-03-2018 CFK41_RS09345 9d0b0fc84ec107f8451554c843835c75 905 SMART SM00482 661 868 3.9E-111 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CFK41_RS09345 9d0b0fc84ec107f8451554c843835c75 905 SMART SM00475 9 269 2.0E-108 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CFK41_RS09345 9d0b0fc84ec107f8451554c843835c75 905 SUPERFAMILY SSF47807 179 291 2.99E-25 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CFK41_RS09345 9d0b0fc84ec107f8451554c843835c75 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 706 719 2.7E-73 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CFK41_RS09345 9d0b0fc84ec107f8451554c843835c75 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 767 778 2.7E-73 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CFK41_RS09345 9d0b0fc84ec107f8451554c843835c75 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 630 652 2.7E-73 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CFK41_RS09345 9d0b0fc84ec107f8451554c843835c75 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 789 800 2.7E-73 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CFK41_RS09345 9d0b0fc84ec107f8451554c843835c75 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 821 837 2.7E-73 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CFK41_RS09345 9d0b0fc84ec107f8451554c843835c75 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 653 668 2.7E-73 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CFK41_RS09345 9d0b0fc84ec107f8451554c843835c75 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 851 864 2.7E-73 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CFK41_RS09345 9d0b0fc84ec107f8451554c843835c75 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 730 755 2.7E-73 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CFK41_RS09345 9d0b0fc84ec107f8451554c843835c75 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 676 699 2.7E-73 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CFK41_RS09345 9d0b0fc84ec107f8451554c843835c75 905 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 11 178 1.1E-50 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CFK41_RS09345 9d0b0fc84ec107f8451554c843835c75 905 Gene3D G3DSA:3.30.70.370 630 718 3.7E-15 T 28-03-2018 CFK41_RS09345 9d0b0fc84ec107f8451554c843835c75 905 Gene3D G3DSA:3.30.70.370 730 905 3.8E-46 T 28-03-2018 CFK41_RS09345 9d0b0fc84ec107f8451554c843835c75 905 TIGRFAM TIGR00593 pola: DNA polymerase I 12 903 7.3E-257 T 28-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CFK41_RS09345 9d0b0fc84ec107f8451554c843835c75 905 SUPERFAMILY SSF88723 8 178 1.68E-50 T 28-03-2018 IPR029060 PIN domain-like CFK41_RS09345 9d0b0fc84ec107f8451554c843835c75 905 SUPERFAMILY SSF56672 497 903 4.0E-128 T 28-03-2018 CFK41_RS09345 9d0b0fc84ec107f8451554c843835c75 905 Gene3D G3DSA:3.40.50.1010 9 187 1.1E-62 T 28-03-2018 IPR029060 PIN domain-like CFK41_RS09345 9d0b0fc84ec107f8451554c843835c75 905 SMART SM00279 181 216 1.8E-10 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CFK41_RS09345 9d0b0fc84ec107f8451554c843835c75 905 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 179 265 3.9E-20 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CFK41_RS09345 9d0b0fc84ec107f8451554c843835c75 905 Pfam PF00476 DNA polymerase family A 523 902 3.8E-133 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CFK41_RS09345 9d0b0fc84ec107f8451554c843835c75 905 Gene3D G3DSA:1.10.150.20 188 250 2.6E-20 T 28-03-2018 CFK41_RS02155 4f3a90f4abb5e382ad1e5a9bc14671cb 1139 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 241 364 1.1E-10 T 28-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 CFK41_RS02155 4f3a90f4abb5e382ad1e5a9bc14671cb 1139 Gene3D G3DSA:3.40.50.300 2 167 4.2E-36 T 28-03-2018 CFK41_RS02155 4f3a90f4abb5e382ad1e5a9bc14671cb 1139 Gene3D G3DSA:1.10.8.60 168 256 5.7E-9 T 28-03-2018 CFK41_RS02155 4f3a90f4abb5e382ad1e5a9bc14671cb 1139 Pfam PF13177 DNA polymerase III, delta subunit 19 177 3.1E-36 T 28-03-2018 CFK41_RS02155 4f3a90f4abb5e382ad1e5a9bc14671cb 1139 SUPERFAMILY SSF52540 31 221 2.84E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS02155 4f3a90f4abb5e382ad1e5a9bc14671cb 1139 Gene3D G3DSA:1.20.272.10 257 368 1.6E-17 T 28-03-2018 CFK41_RS02155 4f3a90f4abb5e382ad1e5a9bc14671cb 1139 SUPERFAMILY SSF48019 246 363 4.0E-15 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CFK41_RS02155 4f3a90f4abb5e382ad1e5a9bc14671cb 1139 SMART SM00382 36 184 2.0E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS02155 4f3a90f4abb5e382ad1e5a9bc14671cb 1139 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 361 2.4E-110 T 28-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 CFK41_RS12395 bc19d0348f4e5c9b47e0343fe0114243 949 SUPERFAMILY SSF52540 114 657 8.89E-180 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS12395 bc19d0348f4e5c9b47e0343fe0114243 949 SUPERFAMILY SSF52540 732 820 8.89E-180 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS12395 bc19d0348f4e5c9b47e0343fe0114243 949 Gene3D G3DSA:3.40.50.300 498 828 3.1E-48 T 28-03-2018 CFK41_RS12395 bc19d0348f4e5c9b47e0343fe0114243 949 Gene3D G3DSA:3.40.50.300 395 497 2.8E-28 T 28-03-2018 CFK41_RS12395 bc19d0348f4e5c9b47e0343fe0114243 949 Pfam PF00580 UvrD/REP helicase N-terminal domain 117 385 5.2E-76 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CFK41_RS12395 bc19d0348f4e5c9b47e0343fe0114243 949 Pfam PF13361 UvrD-like helicase C-terminal domain 390 794 7.2E-67 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CFK41_RS12395 bc19d0348f4e5c9b47e0343fe0114243 949 Gene3D G3DSA:3.40.50.300 252 394 8.6E-34 T 28-03-2018 CFK41_RS12395 bc19d0348f4e5c9b47e0343fe0114243 949 Gene3D G3DSA:3.40.50.300 111 251 7.7E-29 T 28-03-2018 CFK41_RS02520 5f65f7c6756f7dd697f54f9436e9aca9 629 Gene3D G3DSA:1.20.120.160 481 600 3.9E-6 T 28-03-2018 CFK41_RS02520 5f65f7c6756f7dd697f54f9436e9aca9 629 SUPERFAMILY SSF53448 82 351 7.41E-26 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS02520 5f65f7c6756f7dd697f54f9436e9aca9 629 SUPERFAMILY SSF47226 494 601 9.81E-9 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CFK41_RS02520 5f65f7c6756f7dd697f54f9436e9aca9 629 Pfam PF13641 Glycosyltransferase like family 2 82 333 1.8E-24 T 28-03-2018 CFK41_RS02520 5f65f7c6756f7dd697f54f9436e9aca9 629 Gene3D G3DSA:3.90.550.10 59 362 5.6E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS01950 9b91866276c16913b073d8d4461727ec 462 SUPERFAMILY SSF55031 226 336 9.03E-22 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CFK41_RS01950 9b91866276c16913b073d8d4461727ec 462 Pfam PF07687 Peptidase dimerisation domain 228 319 6.8E-8 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CFK41_RS01950 9b91866276c16913b073d8d4461727ec 462 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 71 410 3.8E-71 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CFK41_RS01950 9b91866276c16913b073d8d4461727ec 462 Gene3D G3DSA:3.40.630.10 359 454 4.2E-13 T 28-03-2018 CFK41_RS01950 9b91866276c16913b073d8d4461727ec 462 PIRSF PIRSF037226 49 456 5.5E-110 T 28-03-2018 IPR017144 Peptidase M20A, amidohydrolase, predicted CFK41_RS01950 9b91866276c16913b073d8d4461727ec 462 Gene3D G3DSA:3.40.630.10 19 323 3.6E-48 T 28-03-2018 CFK41_RS01950 9b91866276c16913b073d8d4461727ec 462 Pfam PF01546 Peptidase family M20/M25/M40 138 403 5.7E-11 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CFK41_RS01950 9b91866276c16913b073d8d4461727ec 462 SUPERFAMILY SSF53187 61 241 4.96E-54 T 28-03-2018 CFK41_RS01950 9b91866276c16913b073d8d4461727ec 462 SUPERFAMILY SSF53187 342 438 4.96E-54 T 28-03-2018 CFK41_RS07205 7b24c4b78a89a734efe6f845c83d444a 501 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 17 481 3.1E-180 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CFK41_RS07205 7b24c4b78a89a734efe6f845c83d444a 501 Gene3D G3DSA:3.90.1300.10 2 485 2.3E-165 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CFK41_RS07205 7b24c4b78a89a734efe6f845c83d444a 501 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 12 482 88.2 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CFK41_RS07205 7b24c4b78a89a734efe6f845c83d444a 501 ProSitePatterns PS00571 Amidases signature. 153 184 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CFK41_RS07205 7b24c4b78a89a734efe6f845c83d444a 501 Pfam PF01425 Amidase 25 470 2.3E-155 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CFK41_RS07205 7b24c4b78a89a734efe6f845c83d444a 501 SUPERFAMILY SSF75304 1 482 1.02E-155 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CFK41_RS02870 438f9cc0d6b8cb13666de172a8d53555 578 Pfam PF00664 ABC transporter transmembrane region 18 286 2.9E-38 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS02870 438f9cc0d6b8cb13666de172a8d53555 578 SMART SM00382 361 553 2.8E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS02870 438f9cc0d6b8cb13666de172a8d53555 578 Pfam PF00005 ABC transporter 352 499 3.2E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS02870 438f9cc0d6b8cb13666de172a8d53555 578 Gene3D G3DSA:1.20.1560.10 2 318 3.1E-70 T 28-03-2018 CFK41_RS02870 438f9cc0d6b8cb13666de172a8d53555 578 Gene3D G3DSA:3.40.50.300 319 577 1.7E-62 T 28-03-2018 CFK41_RS02870 438f9cc0d6b8cb13666de172a8d53555 578 SUPERFAMILY SSF90123 7 316 5.76E-69 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS02870 438f9cc0d6b8cb13666de172a8d53555 578 SUPERFAMILY SSF52540 332 571 5.78E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS02870 438f9cc0d6b8cb13666de172a8d53555 578 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS11595 5235b0c620aec4bf665b972bce568616 673 Pfam PF00270 DEAD/DEAH box helicase 41 98 6.0E-6 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CFK41_RS11595 5235b0c620aec4bf665b972bce568616 673 SMART SM00487 29 329 2.2E-6 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CFK41_RS11595 5235b0c620aec4bf665b972bce568616 673 SUPERFAMILY SSF52540 220 270 3.5E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11595 5235b0c620aec4bf665b972bce568616 673 SUPERFAMILY SSF52540 599 634 3.5E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11595 5235b0c620aec4bf665b972bce568616 673 SUPERFAMILY SSF52540 22 129 3.5E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11595 5235b0c620aec4bf665b972bce568616 673 SUPERFAMILY SSF52540 217 333 2.3E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11595 5235b0c620aec4bf665b972bce568616 673 SUPERFAMILY SSF52540 610 625 2.3E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11595 5235b0c620aec4bf665b972bce568616 673 SUPERFAMILY SSF52540 489 579 2.3E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11595 5235b0c620aec4bf665b972bce568616 673 Gene3D G3DSA:3.40.50.300 485 648 9.4E-7 T 28-03-2018 CFK41_RS11595 5235b0c620aec4bf665b972bce568616 673 Pfam PF13307 Helicase C-terminal domain 494 653 2.3E-29 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CFK41_RS11595 5235b0c620aec4bf665b972bce568616 673 Gene3D G3DSA:3.40.50.300 32 426 6.2E-26 T 28-03-2018 CFK41_RS11595 5235b0c620aec4bf665b972bce568616 673 SMART SM00491 511 640 1.9E-30 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CFK41_RS11495 9aff3f8968895b5852fb4e254a7698aa 517 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 363 387 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CFK41_RS11495 9aff3f8968895b5852fb4e254a7698aa 517 Pfam PF01098 Cell cycle protein 55 404 1.6E-82 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CFK41_RS11495 9aff3f8968895b5852fb4e254a7698aa 517 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 54 404 2.8E-104 T 28-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 CFK41_RS04515 3668419fd587c423fc1e3ab7ab97df4b 1162 Gene3D G3DSA:2.40.270.10 791 1031 4.5E-66 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS04515 3668419fd587c423fc1e3ab7ab97df4b 1162 Gene3D G3DSA:2.40.270.10 697 790 6.6E-10 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS04515 3668419fd587c423fc1e3ab7ab97df4b 1162 ProSitePatterns PS01166 RNA polymerases beta chain signature. 868 880 - T 28-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS04515 3668419fd587c423fc1e3ab7ab97df4b 1162 Gene3D G3DSA:2.40.50.100 625 696 1.1E-20 T 28-03-2018 CFK41_RS04515 3668419fd587c423fc1e3ab7ab97df4b 1162 Pfam PF04561 RNA polymerase Rpb2, domain 2 168 364 1.9E-26 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS04515 3668419fd587c423fc1e3ab7ab97df4b 1162 Pfam PF04560 RNA polymerase Rpb2, domain 7 1047 1121 1.9E-26 T 28-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS04515 3668419fd587c423fc1e3ab7ab97df4b 1162 Pfam PF04563 RNA polymerase beta subunit 74 409 3.7E-22 T 28-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS04515 3668419fd587c423fc1e3ab7ab97df4b 1162 Pfam PF04565 RNA polymerase Rpb2, domain 3 423 491 5.6E-29 T 28-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS04515 3668419fd587c423fc1e3ab7ab97df4b 1162 Pfam PF10385 RNA polymerase beta subunit external 1 domain 501 567 3.8E-25 T 28-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS04515 3668419fd587c423fc1e3ab7ab97df4b 1162 Gene3D G3DSA:3.90.1800.10 1048 1087 3.0E-11 T 28-03-2018 CFK41_RS04515 3668419fd587c423fc1e3ab7ab97df4b 1162 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 21 1123 12.169 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS04515 3668419fd587c423fc1e3ab7ab97df4b 1162 Gene3D G3DSA:3.90.1100.10 26 266 3.1E-54 T 28-03-2018 CFK41_RS04515 3668419fd587c423fc1e3ab7ab97df4b 1162 Gene3D G3DSA:3.90.1100.10 555 624 2.8E-14 T 28-03-2018 CFK41_RS04515 3668419fd587c423fc1e3ab7ab97df4b 1162 Gene3D G3DSA:3.90.1100.10 273 553 8.0E-82 T 28-03-2018 CFK41_RS04515 3668419fd587c423fc1e3ab7ab97df4b 1162 SUPERFAMILY SSF64484 20 1130 0.0 T 28-03-2018 CFK41_RS04515 3668419fd587c423fc1e3ab7ab97df4b 1162 Pfam PF00562 RNA polymerase Rpb2, domain 6 629 1045 2.6E-149 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS04515 3668419fd587c423fc1e3ab7ab97df4b 1162 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 235 841 1.9E-300 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS00155 359adc5a8d5173a9293c923c5783a248 254 Pfam PF13714 Phosphoenolpyruvate phosphomutase 12 251 1.1E-59 T 28-03-2018 CFK41_RS00155 359adc5a8d5173a9293c923c5783a248 254 Gene3D G3DSA:3.20.20.60 3 254 2.0E-49 T 28-03-2018 CFK41_RS00155 359adc5a8d5173a9293c923c5783a248 254 SUPERFAMILY SSF51621 4 253 4.49E-53 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CFK41_RS15485 2fe4b9ef46405c06babe9cc205c9720a 304 SUPERFAMILY SSF52821 168 295 5.5E-33 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS15485 2fe4b9ef46405c06babe9cc205c9720a 304 ProSitePatterns PS00380 Rhodanese signature 1. 50 61 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CFK41_RS15485 2fe4b9ef46405c06babe9cc205c9720a 304 Pfam PF00581 Rhodanese-like domain 23 134 1.1E-13 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS15485 2fe4b9ef46405c06babe9cc205c9720a 304 Pfam PF00581 Rhodanese-like domain 177 285 1.9E-17 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS15485 2fe4b9ef46405c06babe9cc205c9720a 304 SMART SM00450 162 290 8.6E-21 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS15485 2fe4b9ef46405c06babe9cc205c9720a 304 SMART SM00450 21 138 1.9E-18 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS15485 2fe4b9ef46405c06babe9cc205c9720a 304 Gene3D G3DSA:3.40.250.10 12 155 1.5E-26 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS15485 2fe4b9ef46405c06babe9cc205c9720a 304 Gene3D G3DSA:3.40.250.10 175 301 4.2E-27 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS15485 2fe4b9ef46405c06babe9cc205c9720a 304 SUPERFAMILY SSF52821 15 142 5.24E-35 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS15485 2fe4b9ef46405c06babe9cc205c9720a 304 ProSitePatterns PS00683 Rhodanese C-terminal signature. 274 284 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CFK41_RS05735 42647d31ff683d6385fabda715d146e1 864 Gene3D G3DSA:3.30.70.380 767 863 1.7E-20 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CFK41_RS05735 42647d31ff683d6385fabda715d146e1 864 SUPERFAMILY SSF46955 443 514 8.06E-15 T 28-03-2018 IPR009061 Putative DNA-binding domain CFK41_RS05735 42647d31ff683d6385fabda715d146e1 864 SMART SM00896 770 863 1.3E-32 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CFK41_RS05735 42647d31ff683d6385fabda715d146e1 864 Gene3D G3DSA:3.30.56.10 441 510 3.4E-19 T 28-03-2018 CFK41_RS05735 42647d31ff683d6385fabda715d146e1 864 Pfam PF03484 tRNA synthetase B5 domain 444 510 6.8E-18 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CFK41_RS05735 42647d31ff683d6385fabda715d146e1 864 Gene3D G3DSA:2.40.50.140 41 170 1.9E-35 T 28-03-2018 CFK41_RS05735 42647d31ff683d6385fabda715d146e1 864 Pfam PF03483 B3/4 domain 249 424 8.4E-66 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CFK41_RS05735 42647d31ff683d6385fabda715d146e1 864 SMART SM00873 249 424 2.2E-85 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CFK41_RS05735 42647d31ff683d6385fabda715d146e1 864 SUPERFAMILY SSF55681 506 622 5.47E-29 T 28-03-2018 CFK41_RS05735 42647d31ff683d6385fabda715d146e1 864 SUPERFAMILY SSF55681 652 757 5.47E-29 T 28-03-2018 CFK41_RS05735 42647d31ff683d6385fabda715d146e1 864 Gene3D G3DSA:3.30.930.10 526 757 1.5E-29 T 28-03-2018 CFK41_RS05735 42647d31ff683d6385fabda715d146e1 864 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 3 863 1.0E-165 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CFK41_RS05735 42647d31ff683d6385fabda715d146e1 864 SMART SM00874 441 510 1.2E-21 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CFK41_RS05735 42647d31ff683d6385fabda715d146e1 864 Pfam PF03147 Ferredoxin-fold anticodon binding domain 770 863 8.2E-22 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CFK41_RS05735 42647d31ff683d6385fabda715d146e1 864 Gene3D G3DSA:3.30.56.10 171 214 2.6E-7 T 28-03-2018 CFK41_RS05735 42647d31ff683d6385fabda715d146e1 864 SUPERFAMILY SSF54991 766 863 1.31E-23 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CFK41_RS05735 42647d31ff683d6385fabda715d146e1 864 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 3 857 37.918 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CFK41_RS05735 42647d31ff683d6385fabda715d146e1 864 SUPERFAMILY SSF56037 248 433 2.28E-67 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CFK41_RS05735 42647d31ff683d6385fabda715d146e1 864 SUPERFAMILY SSF50249 46 219 8.23E-22 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS05735 42647d31ff683d6385fabda715d146e1 864 Gene3D G3DSA:3.50.40.10 228 435 7.9E-73 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CFK41_RS05735 42647d31ff683d6385fabda715d146e1 864 Pfam PF01588 Putative tRNA binding domain 47 151 4.3E-6 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CFK41_RS02080 9d64b81a09252aaa1a401a03d55a6e37 194 SUPERFAMILY SSF46689 2 66 1.05E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS02080 9d64b81a09252aaa1a401a03d55a6e37 194 Gene3D G3DSA:1.10.357.10 5 191 7.3E-26 T 28-03-2018 CFK41_RS02080 9d64b81a09252aaa1a401a03d55a6e37 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 4.3E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS03880 8f9657b93c59805884b0a5c4a8b71429 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 6.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS03880 8f9657b93c59805884b0a5c4a8b71429 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 6.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS03880 8f9657b93c59805884b0a5c4a8b71429 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 6.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS03880 8f9657b93c59805884b0a5c4a8b71429 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 1.3E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS03880 8f9657b93c59805884b0a5c4a8b71429 222 SUPERFAMILY SSF52172 3 134 1.85E-32 T 28-03-2018 IPR011006 CheY-like superfamily CFK41_RS03880 8f9657b93c59805884b0a5c4a8b71429 222 SMART SM00421 152 209 7.3E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS03880 8f9657b93c59805884b0a5c4a8b71429 222 Pfam PF00072 Response regulator receiver domain 6 115 4.4E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS03880 8f9657b93c59805884b0a5c4a8b71429 222 SUPERFAMILY SSF46894 145 216 1.53E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CFK41_RS03880 8f9657b93c59805884b0a5c4a8b71429 222 Gene3D G3DSA:1.10.10.10 134 214 6.2E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS03880 8f9657b93c59805884b0a5c4a8b71429 222 Gene3D G3DSA:3.40.50.2300 1 133 5.2E-38 T 28-03-2018 CFK41_RS03880 8f9657b93c59805884b0a5c4a8b71429 222 SMART SM00448 2 115 2.6E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS17430 e99cffc01eb9367954821817b6736fd7 938 SUPERFAMILY SSF101904 555 881 9.02E-93 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CFK41_RS17430 e99cffc01eb9367954821817b6736fd7 938 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 825 864 8.8E-5 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CFK41_RS17430 e99cffc01eb9367954821817b6736fd7 938 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 666 700 9.2E-4 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CFK41_RS17430 e99cffc01eb9367954821817b6736fd7 938 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 722 770 2.5E-9 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CFK41_RS17430 e99cffc01eb9367954821817b6736fd7 938 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 560 605 9.1E-15 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CFK41_RS17430 e99cffc01eb9367954821817b6736fd7 938 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 611 659 2.5E-8 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CFK41_RS17430 e99cffc01eb9367954821817b6736fd7 938 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 776 821 2.6E-12 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CFK41_RS17430 e99cffc01eb9367954821817b6736fd7 938 Gene3D G3DSA:3.30.1360.40 293 389 1.6E-28 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CFK41_RS17430 e99cffc01eb9367954821817b6736fd7 938 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 61 869 0.0 T 28-03-2018 CFK41_RS17430 e99cffc01eb9367954821817b6736fd7 938 Gene3D G3DSA:3.90.199.10 87 269 2.2E-78 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS17430 e99cffc01eb9367954821817b6736fd7 938 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 85 528 1.4E-143 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS17430 e99cffc01eb9367954821817b6736fd7 938 Gene3D G3DSA:1.10.268.10 401 543 1.4E-45 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS17430 e99cffc01eb9367954821817b6736fd7 938 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 55 873 22.241 T 28-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CFK41_RS17430 e99cffc01eb9367954821817b6736fd7 938 Gene3D G3DSA:2.120.10.90 552 871 1.9E-111 T 28-03-2018 CFK41_RS17430 e99cffc01eb9367954821817b6736fd7 938 SUPERFAMILY SSF56719 38 544 2.22E-164 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CFK41_RS17430 e99cffc01eb9367954821817b6736fd7 938 SMART SM00434 64 521 5.3E-258 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS07950 c0c94b37a96905c22212a9f0ab7db0fd 506 SUPERFAMILY SSF103473 23 294 8.89E-24 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS07950 c0c94b37a96905c22212a9f0ab7db0fd 506 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 34 500 2.2E-139 T 28-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 CFK41_RS07950 c0c94b37a96905c22212a9f0ab7db0fd 506 Pfam PF00854 POT family 114 474 1.2E-58 T 28-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 CFK41_RS07950 c0c94b37a96905c22212a9f0ab7db0fd 506 SUPERFAMILY SSF103473 249 501 3.01E-9 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS07950 c0c94b37a96905c22212a9f0ab7db0fd 506 Gene3D G3DSA:1.20.1250.20 37 235 1.2E-22 T 28-03-2018 CFK41_RS07950 c0c94b37a96905c22212a9f0ab7db0fd 506 Gene3D G3DSA:1.20.1250.20 301 503 6.1E-10 T 28-03-2018 CFK41_RS07950 c0c94b37a96905c22212a9f0ab7db0fd 506 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 176 188 - T 28-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 CFK41_RS16225 cfbfb1e0da0b0b44c1b27c3c2607c00b 228 Gene3D G3DSA:1.10.10.10 146 216 5.8E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS16225 cfbfb1e0da0b0b44c1b27c3c2607c00b 228 Pfam PF00293 NUDIX domain 8 135 1.3E-15 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CFK41_RS16225 cfbfb1e0da0b0b44c1b27c3c2607c00b 228 SUPERFAMILY SSF55811 7 147 4.2E-29 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CFK41_RS16225 cfbfb1e0da0b0b44c1b27c3c2607c00b 228 SUPERFAMILY SSF46785 151 218 7.21E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS16225 cfbfb1e0da0b0b44c1b27c3c2607c00b 228 Gene3D G3DSA:3.90.79.10 9 145 5.7E-37 T 28-03-2018 CFK41_RS06585 c8390881e52e6da89737b1a6fd07dd8a 287 Pfam PF01380 SIS domain 134 261 2.5E-18 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CFK41_RS06585 c8390881e52e6da89737b1a6fd07dd8a 287 Gene3D G3DSA:3.40.50.10490 97 287 4.7E-33 T 28-03-2018 CFK41_RS06585 c8390881e52e6da89737b1a6fd07dd8a 287 SUPERFAMILY SSF46689 1 77 1.77E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS06585 c8390881e52e6da89737b1a6fd07dd8a 287 Pfam PF01418 Helix-turn-helix domain, rpiR family 4 76 5.0E-20 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CFK41_RS06585 c8390881e52e6da89737b1a6fd07dd8a 287 Gene3D G3DSA:1.10.10.10 2 81 6.7E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS06585 c8390881e52e6da89737b1a6fd07dd8a 287 SUPERFAMILY SSF53697 113 282 1.13E-31 T 28-03-2018 CFK41_RS09400 7b1b80b0fa61ca3e0ec165aa6934bb5b 394 Pfam PF00107 Zinc-binding dehydrogenase 189 255 6.2E-11 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CFK41_RS09400 7b1b80b0fa61ca3e0ec165aa6934bb5b 394 Gene3D G3DSA:3.90.180.10 1 178 7.7E-45 T 28-03-2018 CFK41_RS09400 7b1b80b0fa61ca3e0ec165aa6934bb5b 394 Gene3D G3DSA:3.40.50.720 179 344 1.0E-27 T 28-03-2018 CFK41_RS09400 7b1b80b0fa61ca3e0ec165aa6934bb5b 394 SUPERFAMILY SSF50129 2 177 3.04E-57 T 28-03-2018 IPR011032 GroES-like CFK41_RS09400 7b1b80b0fa61ca3e0ec165aa6934bb5b 394 SUPERFAMILY SSF51735 156 350 1.74E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS09400 7b1b80b0fa61ca3e0ec165aa6934bb5b 394 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 141 4.3E-27 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CFK41_RS09400 7b1b80b0fa61ca3e0ec165aa6934bb5b 394 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CFK41_RS09400 7b1b80b0fa61ca3e0ec165aa6934bb5b 394 Pfam PF13823 Alcohol dehydrogenase GroES-associated 2 23 4.0E-10 T 28-03-2018 IPR027399 Alcohol dehydrogenase GroES-associated CFK41_RS04870 ed84f105d06cdda97a584ba51b52d227 433 Gene3D G3DSA:3.30.1490.20 86 185 2.1E-19 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CFK41_RS04870 ed84f105d06cdda97a584ba51b52d227 433 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 291 4.1E-64 T 28-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CFK41_RS04870 ed84f105d06cdda97a584ba51b52d227 433 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 285 292 - T 28-03-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CFK41_RS04870 ed84f105d06cdda97a584ba51b52d227 433 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 2 100 6.3E-28 T 28-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CFK41_RS04870 ed84f105d06cdda97a584ba51b52d227 433 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 419 39.082 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CFK41_RS04870 ed84f105d06cdda97a584ba51b52d227 433 SUPERFAMILY SSF51246 325 416 4.39E-25 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CFK41_RS04870 ed84f105d06cdda97a584ba51b52d227 433 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 2 416 2.1E-140 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CFK41_RS04870 ed84f105d06cdda97a584ba51b52d227 433 Gene3D G3DSA:3.30.470.20 187 324 3.3E-56 T 28-03-2018 CFK41_RS04870 ed84f105d06cdda97a584ba51b52d227 433 Gene3D G3DSA:3.90.600.10 326 419 3.3E-31 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CFK41_RS04870 ed84f105d06cdda97a584ba51b52d227 433 Gene3D G3DSA:3.40.50.20 2 85 3.1E-33 T 28-03-2018 CFK41_RS04870 ed84f105d06cdda97a584ba51b52d227 433 SMART SM01210 326 419 2.8E-41 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CFK41_RS04870 ed84f105d06cdda97a584ba51b52d227 433 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 327 415 1.2E-25 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CFK41_RS04870 ed84f105d06cdda97a584ba51b52d227 433 SMART SM01209 101 291 6.5E-104 T 28-03-2018 CFK41_RS04870 ed84f105d06cdda97a584ba51b52d227 433 SUPERFAMILY SSF56059 102 315 1.62E-52 T 28-03-2018 CFK41_RS04870 ed84f105d06cdda97a584ba51b52d227 433 SUPERFAMILY SSF52440 2 101 1.32E-29 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CFK41_RS09875 2db360a50ddd7f7980e984cb169836ff 570 Gene3D G3DSA:1.20.210.10 29 541 9.2E-186 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS09875 2db360a50ddd7f7980e984cb169836ff 570 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 33 538 4.1E-205 T 28-03-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CFK41_RS09875 2db360a50ddd7f7980e984cb169836ff 570 SUPERFAMILY SSF81442 29 540 1.96E-167 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS09875 2db360a50ddd7f7980e984cb169836ff 570 PRINTS PR01165 Cytochrome c oxidase subunit I signature 79 102 3.3E-96 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS09875 2db360a50ddd7f7980e984cb169836ff 570 PRINTS PR01165 Cytochrome c oxidase subunit I signature 210 229 3.3E-96 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS09875 2db360a50ddd7f7980e984cb169836ff 570 PRINTS PR01165 Cytochrome c oxidase subunit I signature 31 56 3.3E-96 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS09875 2db360a50ddd7f7980e984cb169836ff 570 PRINTS PR01165 Cytochrome c oxidase subunit I signature 328 349 3.3E-96 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS09875 2db360a50ddd7f7980e984cb169836ff 570 PRINTS PR01165 Cytochrome c oxidase subunit I signature 181 199 3.3E-96 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS09875 2db360a50ddd7f7980e984cb169836ff 570 PRINTS PR01165 Cytochrome c oxidase subunit I signature 306 321 3.3E-96 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS09875 2db360a50ddd7f7980e984cb169836ff 570 PRINTS PR01165 Cytochrome c oxidase subunit I signature 106 130 3.3E-96 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS09875 2db360a50ddd7f7980e984cb169836ff 570 PRINTS PR01165 Cytochrome c oxidase subunit I signature 260 281 3.3E-96 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS09875 2db360a50ddd7f7980e984cb169836ff 570 PRINTS PR01165 Cytochrome c oxidase subunit I signature 363 381 3.3E-96 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS09875 2db360a50ddd7f7980e984cb169836ff 570 PRINTS PR01165 Cytochrome c oxidase subunit I signature 391 410 3.3E-96 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS09875 2db360a50ddd7f7980e984cb169836ff 570 PRINTS PR01165 Cytochrome c oxidase subunit I signature 239 260 3.3E-96 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS09875 2db360a50ddd7f7980e984cb169836ff 570 PRINTS PR01165 Cytochrome c oxidase subunit I signature 441 462 3.3E-96 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS09875 2db360a50ddd7f7980e984cb169836ff 570 PRINTS PR01165 Cytochrome c oxidase subunit I signature 149 161 3.3E-96 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS09875 2db360a50ddd7f7980e984cb169836ff 570 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 262 316 - T 28-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS09875 2db360a50ddd7f7980e984cb169836ff 570 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 41 485 7.4E-142 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS00770 d76c58cc12dfe2db933e82d92b4746f6 250 SMART SM00014 96 210 2.9E-15 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CFK41_RS00770 d76c58cc12dfe2db933e82d92b4746f6 250 SUPERFAMILY SSF48317 14 227 1.83E-28 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CFK41_RS00770 d76c58cc12dfe2db933e82d92b4746f6 250 Gene3D G3DSA:1.20.144.10 39 231 5.6E-24 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CFK41_RS00770 d76c58cc12dfe2db933e82d92b4746f6 250 Pfam PF01569 PAP2 superfamily 98 201 2.7E-18 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 SMART SM00433 78 702 0.0 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 46 709 85.177 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 SUPERFAMILY SSF54211 286 460 5.5E-52 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 640 698 3.3E-24 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 PRINTS PR00418 DNA topoisomerase II family signature 156 170 7.3E-62 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 PRINTS PR00418 DNA topoisomerase II family signature 641 657 7.3E-62 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 PRINTS PR00418 DNA topoisomerase II family signature 555 571 7.3E-62 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 PRINTS PR00418 DNA topoisomerase II family signature 489 503 7.3E-62 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 PRINTS PR00418 DNA topoisomerase II family signature 113 126 7.3E-62 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 PRINTS PR00418 DNA topoisomerase II family signature 337 350 7.3E-62 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 PRINTS PR00418 DNA topoisomerase II family signature 78 93 7.3E-62 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 PRINTS PR00418 DNA topoisomerase II family signature 593 605 7.3E-62 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 PRINTS PR00418 DNA topoisomerase II family signature 573 590 7.3E-62 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 Pfam PF00204 DNA gyrase B 286 459 3.5E-58 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 ProSitePatterns PS00177 DNA topoisomerase II signature. 491 499 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 Pfam PF01751 Toprim domain 488 596 3.4E-15 T 28-03-2018 IPR006171 TOPRIM domain CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 SUPERFAMILY SSF56719 463 704 4.18E-80 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 Gene3D G3DSA:3.30.565.10 59 289 9.5E-68 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 SUPERFAMILY SSF55874 48 251 1.65E-65 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 Gene3D G3DSA:3.40.50.670 471 706 7.0E-93 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 Gene3D G3DSA:3.30.230.10 290 461 4.6E-56 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 PRINTS PR01159 DNA gyrase subunit B signature 311 329 3.3E-65 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 PRINTS PR01159 DNA gyrase subunit B signature 662 674 3.3E-65 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 PRINTS PR01159 DNA gyrase subunit B signature 223 238 3.3E-65 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 PRINTS PR01159 DNA gyrase subunit B signature 49 59 3.3E-65 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 PRINTS PR01159 DNA gyrase subunit B signature 238 251 3.3E-65 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 PRINTS PR01159 DNA gyrase subunit B signature 381 397 3.3E-65 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 PRINTS PR01159 DNA gyrase subunit B signature 539 548 3.3E-65 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 PRINTS PR01159 DNA gyrase subunit B signature 285 307 3.3E-65 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 PRINTS PR01159 DNA gyrase subunit B signature 429 443 3.3E-65 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 PRINTS PR01159 DNA gyrase subunit B signature 678 694 3.3E-65 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 PRINTS PR01159 DNA gyrase subunit B signature 443 463 3.3E-65 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 SMART SM00387 74 218 7.6E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 49 709 4.5E-271 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CFK41_RS17435 2121e7ef1585641e7737a79a76ebaf1f 709 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 76 217 4.5E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS05845 590435e8ad47cffac50888524e67637f 335 Gene3D G3DSA:1.10.600.10 3 335 8.6E-91 T 28-03-2018 IPR008949 Isoprenoid synthase domain CFK41_RS05845 590435e8ad47cffac50888524e67637f 335 SUPERFAMILY SSF48576 9 334 3.84E-78 T 28-03-2018 IPR008949 Isoprenoid synthase domain CFK41_RS05845 590435e8ad47cffac50888524e67637f 335 Pfam PF00348 Polyprenyl synthetase 46 257 2.2E-56 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CFK41_RS05845 590435e8ad47cffac50888524e67637f 335 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 211 223 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CFK41_RS02945 45f0fbeb9a2b9bcb2c452ce12004cfd8 406 Pfam PF01545 Cation efflux family 114 306 4.8E-39 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CFK41_RS02945 45f0fbeb9a2b9bcb2c452ce12004cfd8 406 Gene3D G3DSA:3.30.70.1350 305 389 2.2E-11 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CFK41_RS02945 45f0fbeb9a2b9bcb2c452ce12004cfd8 406 Pfam PF16916 Dimerisation domain of Zinc Transporter 313 377 1.6E-9 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CFK41_RS02945 45f0fbeb9a2b9bcb2c452ce12004cfd8 406 SUPERFAMILY SSF161111 109 307 1.7E-46 T 28-03-2018 CFK41_RS02945 45f0fbeb9a2b9bcb2c452ce12004cfd8 406 Gene3D G3DSA:1.20.1510.10 110 304 1.3E-38 T 28-03-2018 CFK41_RS02945 45f0fbeb9a2b9bcb2c452ce12004cfd8 406 SUPERFAMILY SSF160240 318 381 2.09E-9 T 28-03-2018 CFK41_RS02945 45f0fbeb9a2b9bcb2c452ce12004cfd8 406 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 111 379 7.3E-65 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CFK41_RS02765 ff5b6cf930318f55954ad978d06c2099 132 SMART SM00418 2 88 3.4E-19 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS02765 ff5b6cf930318f55954ad978d06c2099 132 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 71 1.0E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS02765 ff5b6cf930318f55954ad978d06c2099 132 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 4 19 1.0E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS02765 ff5b6cf930318f55954ad978d06c2099 132 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 41 56 1.0E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS02765 ff5b6cf930318f55954ad978d06c2099 132 Pfam PF12840 Helix-turn-helix domain 4 65 2.4E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS02765 ff5b6cf930318f55954ad978d06c2099 132 Gene3D G3DSA:1.10.10.10 1 132 7.4E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS02765 ff5b6cf930318f55954ad978d06c2099 132 SUPERFAMILY SSF46785 3 101 1.25E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS15240 016c90cd1f8ebd1187211a4ffc858758 376 SUPERFAMILY SSF55347 136 319 5.4E-26 T 28-03-2018 CFK41_RS15240 016c90cd1f8ebd1187211a4ffc858758 376 Gene3D G3DSA:3.40.50.720 1 146 1.2E-31 T 28-03-2018 CFK41_RS15240 016c90cd1f8ebd1187211a4ffc858758 376 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 11 124 8.6E-19 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS15240 016c90cd1f8ebd1187211a4ffc858758 376 SUPERFAMILY SSF51735 7 154 7.63E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS15240 016c90cd1f8ebd1187211a4ffc858758 376 Gene3D G3DSA:3.30.360.10 147 354 2.1E-31 T 28-03-2018 CFK41_RS02255 8ade8712408e2e9c01511a41f2083c83 430 Gene3D G3DSA:3.30.420.40 232 426 2.2E-44 T 28-03-2018 CFK41_RS02255 8ade8712408e2e9c01511a41f2083c83 430 SUPERFAMILY SSF46785 25 88 4.01E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS02255 8ade8712408e2e9c01511a41f2083c83 430 Pfam PF00480 ROK family 101 416 3.2E-38 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CFK41_RS02255 8ade8712408e2e9c01511a41f2083c83 430 SUPERFAMILY SSF53067 101 418 2.97E-40 T 28-03-2018 CFK41_RS02255 8ade8712408e2e9c01511a41f2083c83 430 Gene3D G3DSA:1.10.10.10 24 91 1.4E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS02255 8ade8712408e2e9c01511a41f2083c83 430 Pfam PF12802 MarR family 34 76 1.9E-6 T 28-03-2018 CFK41_RS02255 8ade8712408e2e9c01511a41f2083c83 430 Gene3D G3DSA:3.30.420.40 92 231 2.0E-23 T 28-03-2018 CFK41_RS13815 5fc90a4f8ba1dcc24360af36c0a387ca 687 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 509 527 8.3E-11 T 28-03-2018 CFK41_RS13815 5fc90a4f8ba1dcc24360af36c0a387ca 687 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 389 408 8.3E-11 T 28-03-2018 CFK41_RS13815 5fc90a4f8ba1dcc24360af36c0a387ca 687 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 17 339 8.4E-64 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CFK41_RS13815 5fc90a4f8ba1dcc24360af36c0a387ca 687 Gene3D G3DSA:3.20.20.70 13 379 6.3E-97 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS13815 5fc90a4f8ba1dcc24360af36c0a387ca 687 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 388 645 3.3E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS13815 5fc90a4f8ba1dcc24360af36c0a387ca 687 Gene3D G3DSA:3.50.50.60 484 636 4.5E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS13815 5fc90a4f8ba1dcc24360af36c0a387ca 687 SUPERFAMILY SSF51905 480 638 9.58E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS13815 5fc90a4f8ba1dcc24360af36c0a387ca 687 SUPERFAMILY SSF51395 10 372 1.39E-93 T 28-03-2018 CFK41_RS13815 5fc90a4f8ba1dcc24360af36c0a387ca 687 Gene3D G3DSA:3.40.50.720 387 483 2.5E-17 T 28-03-2018 CFK41_RS13815 5fc90a4f8ba1dcc24360af36c0a387ca 687 SUPERFAMILY SSF51971 344 527 2.2E-33 T 28-03-2018 CFK41_RS15280 b9afadfe20616167d08261d0775dd0c5 433 Gene3D G3DSA:3.40.50.720 144 297 0.09 T 28-03-2018 CFK41_RS15280 b9afadfe20616167d08261d0775dd0c5 433 SUPERFAMILY SSF51735 17 141 2.05E-11 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS15280 b9afadfe20616167d08261d0775dd0c5 433 Gene3D G3DSA:3.40.50.720 3 143 9.7E-13 T 28-03-2018 CFK41_RS17475 f490d983a02e2d6d3287c4686be9df41 567 ProSitePatterns PS01008 DnaA protein signature. 518 537 - T 28-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CFK41_RS17475 f490d983a02e2d6d3287c4686be9df41 567 Gene3D G3DSA:1.10.1750.10 465 561 3.1E-34 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CFK41_RS17475 f490d983a02e2d6d3287c4686be9df41 567 Gene3D G3DSA:1.10.8.60 389 461 1.9E-26 T 28-03-2018 CFK41_RS17475 f490d983a02e2d6d3287c4686be9df41 567 Gene3D G3DSA:3.40.50.300 217 387 1.3E-22 T 28-03-2018 CFK41_RS17475 f490d983a02e2d6d3287c4686be9df41 567 SUPERFAMILY SSF48295 455 560 2.62E-32 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 CFK41_RS17475 f490d983a02e2d6d3287c4686be9df41 567 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 10 558 1.6E-148 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CFK41_RS17475 f490d983a02e2d6d3287c4686be9df41 567 SMART SM00382 252 383 1.3E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS17475 f490d983a02e2d6d3287c4686be9df41 567 SUPERFAMILY SSF52540 220 435 2.17E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS17475 f490d983a02e2d6d3287c4686be9df41 567 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 518 537 1.7E-49 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CFK41_RS17475 f490d983a02e2d6d3287c4686be9df41 567 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 285 299 1.7E-49 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CFK41_RS17475 f490d983a02e2d6d3287c4686be9df41 567 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 320 334 1.7E-49 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CFK41_RS17475 f490d983a02e2d6d3287c4686be9df41 567 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 354 381 1.7E-49 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CFK41_RS17475 f490d983a02e2d6d3287c4686be9df41 567 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 253 273 1.7E-49 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CFK41_RS17475 f490d983a02e2d6d3287c4686be9df41 567 Pfam PF00308 Bacterial dnaA protein 220 440 5.4E-92 T 28-03-2018 IPR013317 Chromosomal replication initiator protein DnaA CFK41_RS17475 f490d983a02e2d6d3287c4686be9df41 567 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 7 559 31.034 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CFK41_RS17475 f490d983a02e2d6d3287c4686be9df41 567 SMART SM00760 468 537 6.3E-33 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CFK41_RS17475 f490d983a02e2d6d3287c4686be9df41 567 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 471 537 2.4E-27 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CFK41_RS03220 c1ef5a26a9652ecb0d309470f62b12bf 504 Gene3D G3DSA:2.130.10.10 106 353 0.044 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CFK41_RS03220 c1ef5a26a9652ecb0d309470f62b12bf 504 Gene3D G3DSA:2.140.10.10 354 502 3.8E-6 T 28-03-2018 CFK41_RS03220 c1ef5a26a9652ecb0d309470f62b12bf 504 SUPERFAMILY SSF50998 138 202 7.32E-11 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CFK41_RS03220 c1ef5a26a9652ecb0d309470f62b12bf 504 SUPERFAMILY SSF50998 316 496 7.32E-11 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CFK41_RS09555 394d18fc831a2bd8138a40f485df30c2 186 Gene3D G3DSA:2.40.50.140 65 126 3.0E-20 T 28-03-2018 CFK41_RS09555 394d18fc831a2bd8138a40f485df30c2 186 TIGRFAM TIGR00038 efp: translation elongation factor P 3 185 2.3E-72 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CFK41_RS09555 394d18fc831a2bd8138a40f485df30c2 186 SUPERFAMILY SSF50249 129 185 1.51E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS09555 394d18fc831a2bd8138a40f485df30c2 186 SMART SM01185 67 121 2.4E-21 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CFK41_RS09555 394d18fc831a2bd8138a40f485df30c2 186 SUPERFAMILY SSF50249 65 127 7.71E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS09555 394d18fc831a2bd8138a40f485df30c2 186 Gene3D G3DSA:2.40.50.140 129 184 7.6E-25 T 28-03-2018 CFK41_RS09555 394d18fc831a2bd8138a40f485df30c2 186 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 120 9.8E-18 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CFK41_RS09555 394d18fc831a2bd8138a40f485df30c2 186 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 28-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site CFK41_RS09555 394d18fc831a2bd8138a40f485df30c2 186 Hamap MF_00141 Elongation factor P [efp]. 1 185 48.104 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CFK41_RS09555 394d18fc831a2bd8138a40f485df30c2 186 SMART SM00841 129 184 7.2E-30 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CFK41_RS09555 394d18fc831a2bd8138a40f485df30c2 186 Gene3D G3DSA:2.30.30.30 2 61 3.6E-25 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CFK41_RS09555 394d18fc831a2bd8138a40f485df30c2 186 PIRSF PIRSF005901 1 186 1.1E-61 T 28-03-2018 IPR020599 Translation elongation factor P/YeiP CFK41_RS09555 394d18fc831a2bd8138a40f485df30c2 186 Pfam PF09285 Elongation factor P, C-terminal 129 184 1.4E-23 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CFK41_RS09555 394d18fc831a2bd8138a40f485df30c2 186 SUPERFAMILY SSF50104 1 63 1.62E-20 T 28-03-2018 IPR008991 Translation protein SH3-like domain CFK41_RS09555 394d18fc831a2bd8138a40f485df30c2 186 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 1.2E-25 T 28-03-2018 IPR013185 Translation elongation factor, KOW-like CFK41_RS16320 97a88efcd154d1191c0d7a9a8f7c6d31 340 Gene3D G3DSA:1.10.3720.10 53 337 2.2E-42 T 28-03-2018 CFK41_RS16320 97a88efcd154d1191c0d7a9a8f7c6d31 340 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 128 334 4.9E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS16320 97a88efcd154d1191c0d7a9a8f7c6d31 340 SUPERFAMILY SSF161098 97 324 2.22E-48 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS02805 82ee84d62df64e82a488ac327ece6c5b 258 Gene3D G3DSA:3.40.1190.20 2 258 5.2E-45 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS02805 82ee84d62df64e82a488ac327ece6c5b 258 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 17 257 27.978 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CFK41_RS02805 82ee84d62df64e82a488ac327ece6c5b 258 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 167 184 5.4E-28 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CFK41_RS02805 82ee84d62df64e82a488ac327ece6c5b 258 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 93 110 5.4E-28 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CFK41_RS02805 82ee84d62df64e82a488ac327ece6c5b 258 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 23 30 5.4E-28 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CFK41_RS02805 82ee84d62df64e82a488ac327ece6c5b 258 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 36 57 5.4E-28 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CFK41_RS02805 82ee84d62df64e82a488ac327ece6c5b 258 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 123 137 5.4E-28 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CFK41_RS02805 82ee84d62df64e82a488ac327ece6c5b 258 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 67 75 5.4E-28 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CFK41_RS02805 82ee84d62df64e82a488ac327ece6c5b 258 PIRSF PIRSF000513 9 258 3.2E-78 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CFK41_RS02805 82ee84d62df64e82a488ac327ece6c5b 258 SUPERFAMILY SSF53613 9 254 6.11E-51 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS02805 82ee84d62df64e82a488ac327ece6c5b 258 Pfam PF02110 Hydroxyethylthiazole kinase family 15 256 1.5E-64 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CFK41_RS14625 b67ad1b0c91ade550ba8652bd512aa68 411 Gene3D G3DSA:3.40.710.10 1 309 1.5E-119 T 28-03-2018 CFK41_RS14625 b67ad1b0c91ade550ba8652bd512aa68 411 SUPERFAMILY SSF52091 320 394 6.08E-5 T 28-03-2018 IPR002645 STAS domain CFK41_RS14625 b67ad1b0c91ade550ba8652bd512aa68 411 Gene3D G3DSA:3.30.750.24 314 396 0.0039 T 28-03-2018 IPR002645 STAS domain CFK41_RS14625 b67ad1b0c91ade550ba8652bd512aa68 411 TIGRFAM TIGR03814 Gln_ase: glutaminase A 18 307 1.8E-102 T 28-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CFK41_RS14625 b67ad1b0c91ade550ba8652bd512aa68 411 Hamap MF_00313 Glutaminase [glsA]. 5 307 41.012 T 28-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CFK41_RS14625 b67ad1b0c91ade550ba8652bd512aa68 411 SUPERFAMILY SSF56601 4 308 1.19E-106 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CFK41_RS14625 b67ad1b0c91ade550ba8652bd512aa68 411 Pfam PF04960 Glutaminase 22 307 1.5E-112 T 28-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CFK41_RS01225 f6bd8162b4c7e280972c6a984f65a27c 452 SUPERFAMILY SSF51679 3 429 7.72E-108 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CFK41_RS01225 f6bd8162b4c7e280972c6a984f65a27c 452 Pfam PF00296 Luciferase-like monooxygenase 31 380 1.2E-56 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CFK41_RS01225 f6bd8162b4c7e280972c6a984f65a27c 452 Gene3D G3DSA:3.20.20.30 2 449 7.7E-94 T 28-03-2018 CFK41_RS01225 f6bd8162b4c7e280972c6a984f65a27c 452 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 8 426 1.4E-129 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CFK41_RS01225 f6bd8162b4c7e280972c6a984f65a27c 452 PIRSF PIRSF000337 3 443 7.9E-119 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CFK41_RS17335 380701983ac4371e5871a4661f2d78f9 129 Pfam PF01337 Barstar (barnase inhibitor) 5 73 1.9E-6 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) CFK41_RS17335 380701983ac4371e5871a4661f2d78f9 129 SUPERFAMILY SSF52038 1 48 3.66E-7 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) CFK41_RS17335 380701983ac4371e5871a4661f2d78f9 129 Gene3D G3DSA:3.30.370.10 1 124 2.5E-19 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) CFK41_RS16600 bcea6b41d98802957a51a3a31f5eb480 391 Gene3D G3DSA:1.20.1250.20 189 390 4.3E-12 T 28-03-2018 CFK41_RS16600 bcea6b41d98802957a51a3a31f5eb480 391 Gene3D G3DSA:1.20.1250.20 1 176 3.3E-25 T 28-03-2018 CFK41_RS16600 bcea6b41d98802957a51a3a31f5eb480 391 Pfam PF07690 Major Facilitator Superfamily 3 281 2.1E-32 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS16600 bcea6b41d98802957a51a3a31f5eb480 391 SUPERFAMILY SSF103473 3 384 1.83E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS02165 8d1190b93339a3a500745b024cec5a9c 447 SMART SM01149 31 435 4.6E-223 T 28-03-2018 IPR008313 Metal-independent alpha-mannosidase CFK41_RS02165 8d1190b93339a3a500745b024cec5a9c 447 PIRSF PIRSF028846 22 445 5.9E-157 T 28-03-2018 IPR008313 Metal-independent alpha-mannosidase CFK41_RS02165 8d1190b93339a3a500745b024cec5a9c 447 Pfam PF06824 Metal-independent alpha-mannosidase (GH125) 41 433 2.0E-127 T 28-03-2018 IPR008313 Metal-independent alpha-mannosidase CFK41_RS02165 8d1190b93339a3a500745b024cec5a9c 447 Gene3D G3DSA:1.50.10.10 31 446 8.7E-136 T 28-03-2018 CFK41_RS02165 8d1190b93339a3a500745b024cec5a9c 447 SUPERFAMILY SSF48208 39 439 1.65E-145 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CFK41_RS11225 122b4ee234ed45b7bdd670f5bcb56238 321 Pfam PF01636 Phosphotransferase enzyme family 41 247 1.7E-15 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CFK41_RS11225 122b4ee234ed45b7bdd670f5bcb56238 321 Gene3D G3DSA:3.90.1200.10 102 319 5.7E-18 T 28-03-2018 CFK41_RS11225 122b4ee234ed45b7bdd670f5bcb56238 321 SUPERFAMILY SSF56112 40 275 2.48E-23 T 28-03-2018 IPR011009 Protein kinase-like domain CFK41_RS15075 9fb4517eebdd5267dcfc6151cfabaee8 90 PRINTS PR01249 Ribosomal protein L31 signature 2 19 6.4E-16 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS15075 9fb4517eebdd5267dcfc6151cfabaee8 90 PRINTS PR01249 Ribosomal protein L31 signature 45 60 6.4E-16 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS15075 9fb4517eebdd5267dcfc6151cfabaee8 90 PRINTS PR01249 Ribosomal protein L31 signature 60 78 6.4E-16 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS15075 9fb4517eebdd5267dcfc6151cfabaee8 90 SUPERFAMILY SSF143800 1 79 4.32E-21 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS15075 9fb4517eebdd5267dcfc6151cfabaee8 90 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS15075 9fb4517eebdd5267dcfc6151cfabaee8 90 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 79 1.2E-18 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS15075 9fb4517eebdd5267dcfc6151cfabaee8 90 Pfam PF01197 Ribosomal protein L31 1 79 9.6E-28 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS15075 9fb4517eebdd5267dcfc6151cfabaee8 90 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 25.22 T 28-03-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS06100 b885ac807b6c24f2116a7e626ddc8cf0 242 Pfam PF02545 Maf-like protein 16 219 3.6E-38 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 CFK41_RS06100 b885ac807b6c24f2116a7e626ddc8cf0 242 PIRSF PIRSF006305 12 225 1.8E-32 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 CFK41_RS06100 b885ac807b6c24f2116a7e626ddc8cf0 242 Hamap MF_00528 Septum formation protein Maf [maf]. 15 224 24.804 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 CFK41_RS06100 b885ac807b6c24f2116a7e626ddc8cf0 242 Gene3D G3DSA:3.90.950.10 11 222 2.3E-54 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CFK41_RS06100 b885ac807b6c24f2116a7e626ddc8cf0 242 SUPERFAMILY SSF52972 14 219 4.97E-42 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CFK41_RS14200 a3560ca1c98863e7a39e8ffe799367d5 325 SUPERFAMILY SSF161098 80 308 4.97E-55 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS14200 a3560ca1c98863e7a39e8ffe799367d5 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 319 3.8E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS14200 a3560ca1c98863e7a39e8ffe799367d5 325 Gene3D G3DSA:1.10.3720.10 37 322 1.7E-45 T 28-03-2018 CFK41_RS06470 786ed5812d97c138682792a9138ee7f7 796 SMART SM00490 365 450 3.0E-6 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS06470 786ed5812d97c138682792a9138ee7f7 796 Pfam PF00270 DEAD/DEAH box helicase 110 217 5.7E-7 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CFK41_RS06470 786ed5812d97c138682792a9138ee7f7 796 Gene3D G3DSA:3.40.50.300 291 454 5.1E-11 T 28-03-2018 CFK41_RS06470 786ed5812d97c138682792a9138ee7f7 796 Gene3D G3DSA:3.40.50.300 95 253 3.5E-10 T 28-03-2018 CFK41_RS06470 786ed5812d97c138682792a9138ee7f7 796 SUPERFAMILY SSF52540 371 450 5.16E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS06470 786ed5812d97c138682792a9138ee7f7 796 SUPERFAMILY SSF52540 284 339 5.16E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS06470 786ed5812d97c138682792a9138ee7f7 796 SUPERFAMILY SSF52540 112 249 5.16E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS05825 fdda7626187fbe62225c1aeca84181a8 422 SUPERFAMILY SSF52374 2 323 7.31E-95 T 28-03-2018 CFK41_RS05825 fdda7626187fbe62225c1aeca84181a8 422 SUPERFAMILY SSF55174 326 419 5.89E-9 T 28-03-2018 CFK41_RS05825 fdda7626187fbe62225c1aeca84181a8 422 Gene3D G3DSA:1.10.240.10 224 324 7.4E-34 T 28-03-2018 CFK41_RS05825 fdda7626187fbe62225c1aeca84181a8 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 216 228 5.8E-27 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CFK41_RS05825 fdda7626187fbe62225c1aeca84181a8 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 183 205 5.8E-27 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CFK41_RS05825 fdda7626187fbe62225c1aeca84181a8 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 162 177 5.8E-27 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CFK41_RS05825 fdda7626187fbe62225c1aeca84181a8 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 44 66 5.8E-27 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CFK41_RS05825 fdda7626187fbe62225c1aeca84181a8 422 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 4 419 2.7E-108 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CFK41_RS05825 fdda7626187fbe62225c1aeca84181a8 422 Gene3D G3DSA:3.40.50.620 4 223 4.6E-59 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS05825 fdda7626187fbe62225c1aeca84181a8 422 Pfam PF00579 tRNA synthetases class I (W and Y) 30 323 1.0E-76 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS05825 fdda7626187fbe62225c1aeca84181a8 422 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 2 420 42.389 T 28-03-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 CFK41_RS05825 fdda7626187fbe62225c1aeca84181a8 422 Gene3D G3DSA:3.10.290.10 325 422 1.1E-12 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CFK41_RS05825 fdda7626187fbe62225c1aeca84181a8 422 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 40 50 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS14465 cb5f5f7fd0ac640bef5ec56bc6532569 258 ProSitePatterns PS00894 DeoR-type HTH domain signature. 11 45 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CFK41_RS14465 cb5f5f7fd0ac640bef5ec56bc6532569 258 Gene3D G3DSA:1.10.10.10 8 71 3.2E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS14465 cb5f5f7fd0ac640bef5ec56bc6532569 258 SMART SM00420 11 63 3.6E-11 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CFK41_RS14465 cb5f5f7fd0ac640bef5ec56bc6532569 258 Pfam PF00455 DeoR C terminal sensor domain 80 237 3.7E-43 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CFK41_RS14465 cb5f5f7fd0ac640bef5ec56bc6532569 258 Pfam PF08220 DeoR-like helix-turn-helix domain 11 63 1.0E-12 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CFK41_RS14465 cb5f5f7fd0ac640bef5ec56bc6532569 258 SUPERFAMILY SSF46785 9 65 3.33E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS14465 cb5f5f7fd0ac640bef5ec56bc6532569 258 Gene3D G3DSA:3.40.50.1360 78 243 1.2E-31 T 28-03-2018 CFK41_RS14465 cb5f5f7fd0ac640bef5ec56bc6532569 258 SUPERFAMILY SSF100950 79 239 4.02E-26 T 28-03-2018 CFK41_RS14465 cb5f5f7fd0ac640bef5ec56bc6532569 258 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 43 61 7.8E-5 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CFK41_RS14465 cb5f5f7fd0ac640bef5ec56bc6532569 258 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 29 43 7.8E-5 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CFK41_RS14465 cb5f5f7fd0ac640bef5ec56bc6532569 258 SMART SM01134 78 239 2.9E-57 T 28-03-2018 CFK41_RS02105 5e09507fc25498b448bc291bfe47eb00 523 PRINTS PR00175 Sodium/alanine symporter signature 87 109 1.2E-54 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CFK41_RS02105 5e09507fc25498b448bc291bfe47eb00 523 PRINTS PR00175 Sodium/alanine symporter signature 439 459 1.2E-54 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CFK41_RS02105 5e09507fc25498b448bc291bfe47eb00 523 PRINTS PR00175 Sodium/alanine symporter signature 213 232 1.2E-54 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CFK41_RS02105 5e09507fc25498b448bc291bfe47eb00 523 PRINTS PR00175 Sodium/alanine symporter signature 372 394 1.2E-54 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CFK41_RS02105 5e09507fc25498b448bc291bfe47eb00 523 PRINTS PR00175 Sodium/alanine symporter signature 185 203 1.2E-54 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CFK41_RS02105 5e09507fc25498b448bc291bfe47eb00 523 PRINTS PR00175 Sodium/alanine symporter signature 304 322 1.2E-54 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CFK41_RS02105 5e09507fc25498b448bc291bfe47eb00 523 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 87 102 - T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CFK41_RS02105 5e09507fc25498b448bc291bfe47eb00 523 TIGRFAM TIGR00835 agcS: amino acid carrier protein 14 470 3.1E-134 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CFK41_RS02105 5e09507fc25498b448bc291bfe47eb00 523 Pfam PF01235 Sodium:alanine symporter family 50 482 7.2E-153 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CFK41_RS17190 0ec3c511fdc7e73dcd20e8c55e92d18f 330 Gene3D G3DSA:3.40.50.720 3 134 1.3E-33 T 28-03-2018 CFK41_RS17190 0ec3c511fdc7e73dcd20e8c55e92d18f 330 SUPERFAMILY SSF55347 128 253 4.14E-22 T 28-03-2018 CFK41_RS17190 0ec3c511fdc7e73dcd20e8c55e92d18f 330 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 135 219 5.0E-7 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CFK41_RS17190 0ec3c511fdc7e73dcd20e8c55e92d18f 330 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 10 120 7.6E-20 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS17190 0ec3c511fdc7e73dcd20e8c55e92d18f 330 Gene3D G3DSA:3.30.360.10 135 330 1.0E-38 T 28-03-2018 CFK41_RS17190 0ec3c511fdc7e73dcd20e8c55e92d18f 330 SUPERFAMILY SSF51735 7 149 4.15E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS15785 03888c71a1bede2020c81ab147924f9b 355 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 134 5.6E-30 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CFK41_RS15785 03888c71a1bede2020c81ab147924f9b 355 Pfam PF00107 Zinc-binding dehydrogenase 180 307 1.7E-22 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CFK41_RS15785 03888c71a1bede2020c81ab147924f9b 355 Gene3D G3DSA:3.40.50.720 168 295 4.3E-23 T 28-03-2018 CFK41_RS15785 03888c71a1bede2020c81ab147924f9b 355 SUPERFAMILY SSF51735 148 305 5.6E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS15785 03888c71a1bede2020c81ab147924f9b 355 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 63 77 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CFK41_RS15785 03888c71a1bede2020c81ab147924f9b 355 Gene3D G3DSA:3.90.180.10 1 167 1.4E-40 T 28-03-2018 CFK41_RS15785 03888c71a1bede2020c81ab147924f9b 355 SUPERFAMILY SSF50129 1 179 1.89E-43 T 28-03-2018 IPR011032 GroES-like CFK41_RS13110 b84c11ef22e4c8783de3497290f43c70 547 SUPERFAMILY SSF48592 6 133 1.25E-70 T 28-03-2018 CFK41_RS13110 b84c11ef22e4c8783de3497290f43c70 547 SUPERFAMILY SSF48592 404 519 1.25E-70 T 28-03-2018 CFK41_RS13110 b84c11ef22e4c8783de3497290f43c70 547 Gene3D G3DSA:1.10.560.10 371 514 2.9E-23 T 28-03-2018 IPR027413 GroEL-like equatorial domain CFK41_RS13110 b84c11ef22e4c8783de3497290f43c70 547 SUPERFAMILY SSF52029 184 374 1.24E-78 T 28-03-2018 IPR027409 GroEL-like apical domain CFK41_RS13110 b84c11ef22e4c8783de3497290f43c70 547 Gene3D G3DSA:3.50.7.10 181 370 3.4E-92 T 28-03-2018 IPR027409 GroEL-like apical domain CFK41_RS13110 b84c11ef22e4c8783de3497290f43c70 547 Hamap MF_00600 60 kDa chaperonin [groL]. 1 546 40.898 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CFK41_RS13110 b84c11ef22e4c8783de3497290f43c70 547 PRINTS PR00298 60kDa chaperonin signature 266 289 1.2E-69 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CFK41_RS13110 b84c11ef22e4c8783de3497290f43c70 547 PRINTS PR00298 60kDa chaperonin signature 82 109 1.2E-69 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CFK41_RS13110 b84c11ef22e4c8783de3497290f43c70 547 PRINTS PR00298 60kDa chaperonin signature 348 373 1.2E-69 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CFK41_RS13110 b84c11ef22e4c8783de3497290f43c70 547 PRINTS PR00298 60kDa chaperonin signature 26 52 1.2E-69 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CFK41_RS13110 b84c11ef22e4c8783de3497290f43c70 547 PRINTS PR00298 60kDa chaperonin signature 396 417 1.2E-69 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CFK41_RS13110 b84c11ef22e4c8783de3497290f43c70 547 SUPERFAMILY SSF54849 136 202 2.29E-25 T 28-03-2018 CFK41_RS13110 b84c11ef22e4c8783de3497290f43c70 547 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 523 4.4E-89 T 28-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CFK41_RS13110 b84c11ef22e4c8783de3497290f43c70 547 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 28-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CFK41_RS13110 b84c11ef22e4c8783de3497290f43c70 547 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 2.9E-244 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CFK41_RS13110 b84c11ef22e4c8783de3497290f43c70 547 Gene3D G3DSA:1.10.560.10 2 180 1.4E-39 T 28-03-2018 IPR027413 GroEL-like equatorial domain CFK41_RS06285 8da427fb8a8663585e3c3ac8450aef80 597 Gene3D G3DSA:2.20.25.10 551 591 5.2E-10 T 28-03-2018 CFK41_RS06285 8da427fb8a8663585e3c3ac8450aef80 597 SUPERFAMILY SSF53738 168 271 3.53E-26 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS06285 8da427fb8a8663585e3c3ac8450aef80 597 SUPERFAMILY SSF53738 286 383 3.1E-26 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS06285 8da427fb8a8663585e3c3ac8450aef80 597 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 25 135 2.4E-26 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS06285 8da427fb8a8663585e3c3ac8450aef80 597 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 169 269 2.9E-22 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS06285 8da427fb8a8663585e3c3ac8450aef80 597 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 106 115 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS06285 8da427fb8a8663585e3c3ac8450aef80 597 Gene3D G3DSA:3.40.120.10 22 171 3.1E-29 T 28-03-2018 CFK41_RS06285 8da427fb8a8663585e3c3ac8450aef80 597 SUPERFAMILY SSF53738 25 179 4.32E-27 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS06285 8da427fb8a8663585e3c3ac8450aef80 597 SUPERFAMILY SSF158997 547 592 1.24E-8 T 28-03-2018 CFK41_RS06285 8da427fb8a8663585e3c3ac8450aef80 597 Gene3D G3DSA:3.40.120.10 280 384 9.3E-26 T 28-03-2018 CFK41_RS06285 8da427fb8a8663585e3c3ac8450aef80 597 Gene3D G3DSA:3.30.310.50 385 484 5.8E-14 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS06285 8da427fb8a8663585e3c3ac8450aef80 597 SUPERFAMILY SSF55957 387 477 9.42E-14 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS06285 8da427fb8a8663585e3c3ac8450aef80 597 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 105 119 4.6E-21 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS06285 8da427fb8a8663585e3c3ac8450aef80 597 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 220 233 4.6E-21 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS06285 8da427fb8a8663585e3c3ac8450aef80 597 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 185 204 4.6E-21 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS06285 8da427fb8a8663585e3c3ac8450aef80 597 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 249 264 4.6E-21 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS06285 8da427fb8a8663585e3c3ac8450aef80 597 Gene3D G3DSA:3.40.120.10 172 279 5.8E-30 T 28-03-2018 CFK41_RS06285 8da427fb8a8663585e3c3ac8450aef80 597 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 393 475 4.5E-9 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS06285 8da427fb8a8663585e3c3ac8450aef80 597 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 275 385 1.4E-24 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS04775 436981ac2492996fcdb3ac9c3072902e 725 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 68 157 2.6E-8 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CFK41_RS04775 436981ac2492996fcdb3ac9c3072902e 725 Gene3D G3DSA:1.20.140.10 292 484 1.6E-38 T 28-03-2018 CFK41_RS04775 436981ac2492996fcdb3ac9c3072902e 725 Gene3D G3DSA:1.20.140.10 527 661 2.8E-25 T 28-03-2018 CFK41_RS04775 436981ac2492996fcdb3ac9c3072902e 725 PIRSF PIRSF000168 41 714 1.2E-152 T 28-03-2018 IPR012258 Acyl-CoA oxidase GO:0003997|GO:0005777|GO:0006631|GO:0071949 KEGG: 00071+1.3.3.6|KEGG: 00592+1.3.3.6|MetaCyc: PWY-5136|MetaCyc: PWY-6837|MetaCyc: PWY-6920|MetaCyc: PWY-7007|MetaCyc: PWY-7288|MetaCyc: PWY-7291|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7574|MetaCyc: PWY-7606|MetaCyc: PWY-7726|MetaCyc: PWY-7854|MetaCyc: PWY-7858 CFK41_RS04775 436981ac2492996fcdb3ac9c3072902e 725 SUPERFAMILY SSF47203 305 480 4.19E-46 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CFK41_RS04775 436981ac2492996fcdb3ac9c3072902e 725 SUPERFAMILY SSF56645 58 292 3.14E-50 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CFK41_RS04775 436981ac2492996fcdb3ac9c3072902e 725 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 163 275 1.3E-15 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CFK41_RS04775 436981ac2492996fcdb3ac9c3072902e 725 SUPERFAMILY SSF47203 524 672 6.44E-25 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CFK41_RS04775 436981ac2492996fcdb3ac9c3072902e 725 Gene3D G3DSA:2.40.110.10 162 291 3.2E-28 T 28-03-2018 CFK41_RS04775 436981ac2492996fcdb3ac9c3072902e 725 Gene3D G3DSA:1.10.540.10 37 160 6.0E-17 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CFK41_RS04775 436981ac2492996fcdb3ac9c3072902e 725 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 309 470 2.3E-10 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CFK41_RS04775 436981ac2492996fcdb3ac9c3072902e 725 Pfam PF01756 Acyl-CoA oxidase 531 666 6.2E-15 T 28-03-2018 IPR002655 Acyl-CoA oxidase, C-terminal GO:0003997|GO:0005777|GO:0006635 KEGG: 00071+1.3.3.6|KEGG: 00592+1.3.3.6|MetaCyc: PWY-5136|MetaCyc: PWY-6837|MetaCyc: PWY-6920|MetaCyc: PWY-7007|MetaCyc: PWY-7288|MetaCyc: PWY-7291|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7574|MetaCyc: PWY-7606|MetaCyc: PWY-7726|MetaCyc: PWY-7854|MetaCyc: PWY-7858 CFK41_RS13525 8b9984c1e14cdbfd08ed5f54c8d39db9 440 Pfam PF00535 Glycosyl transferase family 2 17 84 3.3E-13 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CFK41_RS13525 8b9984c1e14cdbfd08ed5f54c8d39db9 440 Gene3D G3DSA:3.90.550.10 2 295 7.8E-30 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS13525 8b9984c1e14cdbfd08ed5f54c8d39db9 440 SUPERFAMILY SSF53448 129 266 1.61E-26 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS13525 8b9984c1e14cdbfd08ed5f54c8d39db9 440 SUPERFAMILY SSF53448 13 91 1.61E-26 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS08205 094b7319a4981a6194e81c99153b8ece 409 Pfam PF00892 EamA-like transporter family 220 352 6.3E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CFK41_RS08205 094b7319a4981a6194e81c99153b8ece 409 SUPERFAMILY SSF103481 117 207 3.01E-5 T 28-03-2018 CFK41_RS08205 094b7319a4981a6194e81c99153b8ece 409 SUPERFAMILY SSF103481 261 357 5.23E-6 T 28-03-2018 CFK41_RS16070 a41f4dd38fb4149b09325c6875d955e6 829 Gene3D G3DSA:3.50.50.60 6 590 3.7E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS16070 a41f4dd38fb4149b09325c6875d955e6 829 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 616 680 2.8E-6 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CFK41_RS16070 a41f4dd38fb4149b09325c6875d955e6 829 Gene3D G3DSA:3.40.50.720 615 806 9.3E-16 T 28-03-2018 CFK41_RS16070 a41f4dd38fb4149b09325c6875d955e6 829 SUPERFAMILY SSF51735 616 808 4.72E-20 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS16070 a41f4dd38fb4149b09325c6875d955e6 829 Pfam PF13454 FAD-NAD(P)-binding 12 190 1.3E-40 T 28-03-2018 CFK41_RS16070 a41f4dd38fb4149b09325c6875d955e6 829 SUPERFAMILY SSF51905 6 250 9.5E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS13750 ba12c9731dde3256c2a031a74ea2cf0b 412 Gene3D G3DSA:1.20.1250.20 6 196 5.2E-19 T 28-03-2018 CFK41_RS13750 ba12c9731dde3256c2a031a74ea2cf0b 412 Gene3D G3DSA:1.20.1250.20 212 399 1.1E-13 T 28-03-2018 CFK41_RS13750 ba12c9731dde3256c2a031a74ea2cf0b 412 Pfam PF07690 Major Facilitator Superfamily 12 359 4.4E-24 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS13750 ba12c9731dde3256c2a031a74ea2cf0b 412 SUPERFAMILY SSF103473 10 397 6.67E-39 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS08530 fd4cf67a17bbfceb7374402d4f9ff3d7 467 Gene3D G3DSA:3.30.390.30 346 467 2.0E-27 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CFK41_RS08530 fd4cf67a17bbfceb7374402d4f9ff3d7 467 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 43 53 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CFK41_RS08530 fd4cf67a17bbfceb7374402d4f9ff3d7 467 Gene3D G3DSA:3.50.50.60 1 164 9.3E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS08530 fd4cf67a17bbfceb7374402d4f9ff3d7 467 Gene3D G3DSA:3.40.50.720 165 333 2.0E-32 T 28-03-2018 CFK41_RS08530 fd4cf67a17bbfceb7374402d4f9ff3d7 467 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 326 3.0E-64 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS08530 fd4cf67a17bbfceb7374402d4f9ff3d7 467 SUPERFAMILY SSF51905 5 334 1.47E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS08530 fd4cf67a17bbfceb7374402d4f9ff3d7 467 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 8 464 1.2E-130 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CFK41_RS08530 fd4cf67a17bbfceb7374402d4f9ff3d7 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 291 313 3.9E-34 T 28-03-2018 CFK41_RS08530 fd4cf67a17bbfceb7374402d4f9ff3d7 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 139 157 3.9E-34 T 28-03-2018 CFK41_RS08530 fd4cf67a17bbfceb7374402d4f9ff3d7 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 177 195 3.9E-34 T 28-03-2018 CFK41_RS08530 fd4cf67a17bbfceb7374402d4f9ff3d7 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 3.9E-34 T 28-03-2018 CFK41_RS08530 fd4cf67a17bbfceb7374402d4f9ff3d7 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 278 3.9E-34 T 28-03-2018 CFK41_RS08530 fd4cf67a17bbfceb7374402d4f9ff3d7 467 SUPERFAMILY SSF55424 348 464 8.42E-27 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CFK41_RS08530 fd4cf67a17bbfceb7374402d4f9ff3d7 467 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 348 454 3.9E-21 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CFK41_RS08530 fd4cf67a17bbfceb7374402d4f9ff3d7 467 PIRSF PIRSF000350 1 442 6.7E-63 T 28-03-2018 CFK41_RS08530 fd4cf67a17bbfceb7374402d4f9ff3d7 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 407 422 7.8E-59 T 28-03-2018 CFK41_RS08530 fd4cf67a17bbfceb7374402d4f9ff3d7 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 177 202 7.8E-59 T 28-03-2018 CFK41_RS08530 fd4cf67a17bbfceb7374402d4f9ff3d7 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 306 313 7.8E-59 T 28-03-2018 CFK41_RS08530 fd4cf67a17bbfceb7374402d4f9ff3d7 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 429 449 7.8E-59 T 28-03-2018 CFK41_RS08530 fd4cf67a17bbfceb7374402d4f9ff3d7 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 342 363 7.8E-59 T 28-03-2018 CFK41_RS08530 fd4cf67a17bbfceb7374402d4f9ff3d7 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 142 151 7.8E-59 T 28-03-2018 CFK41_RS08530 fd4cf67a17bbfceb7374402d4f9ff3d7 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 7.8E-59 T 28-03-2018 CFK41_RS08530 fd4cf67a17bbfceb7374402d4f9ff3d7 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 42 57 7.8E-59 T 28-03-2018 CFK41_RS08530 fd4cf67a17bbfceb7374402d4f9ff3d7 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 263 277 7.8E-59 T 28-03-2018 CFK41_RS05800 11741831ec151a492cdc5c48699afdab 410 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 221 259 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CFK41_RS05800 11741831ec151a492cdc5c48699afdab 410 Pfam PF00202 Aminotransferase class-III 28 390 9.5E-104 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CFK41_RS05800 11741831ec151a492cdc5c48699afdab 410 Gene3D G3DSA:3.40.640.10 166 292 2.4E-39 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS05800 11741831ec151a492cdc5c48699afdab 410 PIRSF PIRSF000521 27 130 5.0E-11 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CFK41_RS05800 11741831ec151a492cdc5c48699afdab 410 PIRSF PIRSF000521 168 398 1.1E-32 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CFK41_RS05800 11741831ec151a492cdc5c48699afdab 410 PIRSF PIRSF000521 124 156 0.015 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CFK41_RS05800 11741831ec151a492cdc5c48699afdab 410 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 15 396 42.758 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CFK41_RS05800 11741831ec151a492cdc5c48699afdab 410 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 19 394 7.3E-131 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CFK41_RS05800 11741831ec151a492cdc5c48699afdab 410 Gene3D G3DSA:3.90.1150.10 2 161 5.6E-47 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS05800 11741831ec151a492cdc5c48699afdab 410 SUPERFAMILY SSF53383 21 395 3.06E-116 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS05800 11741831ec151a492cdc5c48699afdab 410 Gene3D G3DSA:3.90.1150.10 293 402 2.3E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS04165 fad41bdbda1207ce06876501f18c88f6 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 213 2.1E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS04165 fad41bdbda1207ce06876501f18c88f6 223 SUPERFAMILY SSF52172 2 139 7.26E-32 T 28-03-2018 IPR011006 CheY-like superfamily CFK41_RS04165 fad41bdbda1207ce06876501f18c88f6 223 SMART SM00448 3 120 3.1E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS04165 fad41bdbda1207ce06876501f18c88f6 223 SUPERFAMILY SSF46894 142 220 1.16E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CFK41_RS04165 fad41bdbda1207ce06876501f18c88f6 223 SMART SM00421 156 213 4.2E-25 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS04165 fad41bdbda1207ce06876501f18c88f6 223 ProSitePatterns PS00622 LuxR-type HTH domain signature. 173 200 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS04165 fad41bdbda1207ce06876501f18c88f6 223 Gene3D G3DSA:3.40.50.2300 2 138 4.2E-37 T 28-03-2018 CFK41_RS04165 fad41bdbda1207ce06876501f18c88f6 223 Gene3D G3DSA:1.10.10.10 139 218 3.0E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS04165 fad41bdbda1207ce06876501f18c88f6 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 201 1.8E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS04165 fad41bdbda1207ce06876501f18c88f6 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 173 1.8E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS04165 fad41bdbda1207ce06876501f18c88f6 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 189 1.8E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS04165 fad41bdbda1207ce06876501f18c88f6 223 Pfam PF00072 Response regulator receiver domain 5 121 1.5E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS03735 307b5af11a93febd88f7d3b04787e528 473 SUPERFAMILY SSF51905 10 219 1.42E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS03735 307b5af11a93febd88f7d3b04787e528 473 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 167 181 1.4E-16 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CFK41_RS03735 307b5af11a93febd88f7d3b04787e528 473 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 194 209 1.4E-16 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CFK41_RS03735 307b5af11a93febd88f7d3b04787e528 473 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 12 28 1.4E-16 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CFK41_RS03735 307b5af11a93febd88f7d3b04787e528 473 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 84 99 1.4E-16 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CFK41_RS03735 307b5af11a93febd88f7d3b04787e528 473 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 359 376 1.4E-16 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CFK41_RS03735 307b5af11a93febd88f7d3b04787e528 473 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 312 339 1.4E-16 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CFK41_RS03735 307b5af11a93febd88f7d3b04787e528 473 Pfam PF00743 Flavin-binding monooxygenase-like 12 389 2.0E-27 T 28-03-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 CFK41_RS03735 307b5af11a93febd88f7d3b04787e528 473 Gene3D G3DSA:3.50.50.60 165 325 3.4E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS03735 307b5af11a93febd88f7d3b04787e528 473 PIRSF PIRSF000332 10 402 1.7E-36 T 28-03-2018 CFK41_RS03735 307b5af11a93febd88f7d3b04787e528 473 Gene3D G3DSA:3.50.50.60 11 164 1.7E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS03230 9dcc1fd1b162b443a493ac56cd37705e 1001 Gene3D G3DSA:3.20.20.80 299 617 8.3E-71 T 28-03-2018 CFK41_RS03230 9dcc1fd1b162b443a493ac56cd37705e 1001 SUPERFAMILY SSF49785 22 210 1.3E-49 T 28-03-2018 IPR008979 Galactose-binding domain-like CFK41_RS03230 9dcc1fd1b162b443a493ac56cd37705e 1001 SUPERFAMILY SSF74650 744 998 8.79E-58 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CFK41_RS03230 9dcc1fd1b162b443a493ac56cd37705e 1001 Gene3D G3DSA:2.60.40.10 211 298 1.9E-9 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS03230 9dcc1fd1b162b443a493ac56cd37705e 1001 SUPERFAMILY SSF49303 214 299 3.74E-12 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CFK41_RS03230 9dcc1fd1b162b443a493ac56cd37705e 1001 Gene3D G3DSA:2.60.40.10 618 710 5.7E-12 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS03230 9dcc1fd1b162b443a493ac56cd37705e 1001 PRINTS PR00132 Glycosyl hydrolase family 2 signature 340 358 1.7E-29 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CFK41_RS03230 9dcc1fd1b162b443a493ac56cd37705e 1001 PRINTS PR00132 Glycosyl hydrolase family 2 signature 423 438 1.7E-29 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CFK41_RS03230 9dcc1fd1b162b443a493ac56cd37705e 1001 PRINTS PR00132 Glycosyl hydrolase family 2 signature 309 323 1.7E-29 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CFK41_RS03230 9dcc1fd1b162b443a493ac56cd37705e 1001 PRINTS PR00132 Glycosyl hydrolase family 2 signature 524 539 1.7E-29 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CFK41_RS03230 9dcc1fd1b162b443a493ac56cd37705e 1001 PRINTS PR00132 Glycosyl hydrolase family 2 signature 137 152 1.7E-29 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CFK41_RS03230 9dcc1fd1b162b443a493ac56cd37705e 1001 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 300 620 8.1E-86 T 28-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 CFK41_RS03230 9dcc1fd1b162b443a493ac56cd37705e 1001 Gene3D G3DSA:2.60.120.260 23 210 9.8E-45 T 28-03-2018 IPR008979 Galactose-binding domain-like CFK41_RS03230 9dcc1fd1b162b443a493ac56cd37705e 1001 Pfam PF02929 Beta galactosidase small chain 758 995 1.5E-44 T 28-03-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CFK41_RS03230 9dcc1fd1b162b443a493ac56cd37705e 1001 Gene3D G3DSA:2.70.98.10 751 1001 2.5E-63 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CFK41_RS03230 9dcc1fd1b162b443a493ac56cd37705e 1001 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 350 375 - T 28-03-2018 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CFK41_RS03230 9dcc1fd1b162b443a493ac56cd37705e 1001 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 48 210 5.8E-35 T 28-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CFK41_RS03230 9dcc1fd1b162b443a493ac56cd37705e 1001 SUPERFAMILY SSF51445 300 617 6.47E-82 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS03230 9dcc1fd1b162b443a493ac56cd37705e 1001 SUPERFAMILY SSF49303 614 701 1.08E-7 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CFK41_RS03230 9dcc1fd1b162b443a493ac56cd37705e 1001 SMART SM01038 734 997 2.2E-58 T 28-03-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CFK41_RS14155 dc9a8072681dc74426af75ccb31a9f92 320 SMART SM01130 14 307 9.5E-65 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS14155 dc9a8072681dc74426af75ccb31a9f92 320 SUPERFAMILY SSF51569 13 305 1.15E-61 T 28-03-2018 CFK41_RS14155 dc9a8072681dc74426af75ccb31a9f92 320 Pfam PF00701 Dihydrodipicolinate synthetase family 15 305 6.5E-51 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS14155 dc9a8072681dc74426af75ccb31a9f92 320 PIRSF PIRSF001365 11 315 8.0E-54 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS14155 dc9a8072681dc74426af75ccb31a9f92 320 Gene3D G3DSA:3.20.20.70 12 310 2.6E-68 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS14155 dc9a8072681dc74426af75ccb31a9f92 320 Hamap MF_00694 Probable 5-dehydro-4-deoxyglucarate dehydratase. 14 308 41.843 T 28-03-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 CFK41_RS10625 2aa9fcf36a43781fe086491b70845f94 573 Pfam PF00270 DEAD/DEAH box helicase 38 205 5.4E-40 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CFK41_RS10625 2aa9fcf36a43781fe086491b70845f94 573 Gene3D G3DSA:3.40.50.300 233 561 4.1E-37 T 28-03-2018 CFK41_RS10625 2aa9fcf36a43781fe086491b70845f94 573 SUPERFAMILY SSF52540 85 362 2.6E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS10625 2aa9fcf36a43781fe086491b70845f94 573 Gene3D G3DSA:3.40.50.300 2 232 1.8E-49 T 28-03-2018 CFK41_RS10625 2aa9fcf36a43781fe086491b70845f94 573 SMART SM00490 266 347 3.2E-27 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS10625 2aa9fcf36a43781fe086491b70845f94 573 Pfam PF00271 Helicase conserved C-terminal domain 249 347 2.4E-21 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS10625 2aa9fcf36a43781fe086491b70845f94 573 SMART SM00487 32 232 1.6E-41 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CFK41_RS17155 289621af3f6ddfb1dacad8696c77e450 156 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 5 149 2.5E-33 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CFK41_RS17155 289621af3f6ddfb1dacad8696c77e450 156 Gene3D G3DSA:3.40.1400.10 1 155 8.9E-52 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CFK41_RS17155 289621af3f6ddfb1dacad8696c77e450 156 Pfam PF02502 Ribose/Galactose Isomerase 5 146 3.6E-42 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CFK41_RS17155 289621af3f6ddfb1dacad8696c77e450 156 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 3 150 9.0E-61 T 28-03-2018 IPR011860 Ribose 5-phosphate isomerase GO:0004751 CFK41_RS17155 289621af3f6ddfb1dacad8696c77e450 156 SUPERFAMILY SSF89623 3 151 6.02E-46 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CFK41_RS17155 289621af3f6ddfb1dacad8696c77e450 156 PIRSF PIRSF005384 3 152 8.7E-43 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CFK41_RS02235 a7df1439961f02bed3427fdd259e034b 278 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 116 139 7.0E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS02235 a7df1439961f02bed3427fdd259e034b 278 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 95 108 7.0E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS02235 a7df1439961f02bed3427fdd259e034b 278 Pfam PF00440 Bacterial regulatory proteins, tetR family 95 141 5.8E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS02235 a7df1439961f02bed3427fdd259e034b 278 Gene3D G3DSA:1.10.357.10 143 278 8.6E-9 T 28-03-2018 CFK41_RS02235 a7df1439961f02bed3427fdd259e034b 278 Gene3D G3DSA:1.10.10.60 54 116 1.3E-14 T 28-03-2018 CFK41_RS02235 a7df1439961f02bed3427fdd259e034b 278 SUPERFAMILY SSF46689 88 154 1.59E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS02235 a7df1439961f02bed3427fdd259e034b 278 SUPERFAMILY SSF48498 167 256 2.39E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CFK41_RS02235 a7df1439961f02bed3427fdd259e034b 278 Gene3D G3DSA:1.10.260.40 117 142 1.1E-10 T 28-03-2018 CFK41_RS04850 dedde60377ad87e1de2ba7c335c7e859 255 Gene3D G3DSA:3.30.70.930 51 130 1.2E-6 T 28-03-2018 IPR029756 MTH1187/YkoF-like CFK41_RS04850 dedde60377ad87e1de2ba7c335c7e859 255 Gene3D G3DSA:3.30.70.930 144 248 2.1E-9 T 28-03-2018 IPR029756 MTH1187/YkoF-like CFK41_RS04850 dedde60377ad87e1de2ba7c335c7e859 255 SUPERFAMILY SSF89957 54 244 4.57E-24 T 28-03-2018 IPR029756 MTH1187/YkoF-like CFK41_RS04850 dedde60377ad87e1de2ba7c335c7e859 255 Pfam PF07615 YKOF-related Family 159 244 9.6E-12 T 28-03-2018 IPR011522 Thiamin/hydroxymethyl pyrimidine-binding YkoF, putative CFK41_RS04850 dedde60377ad87e1de2ba7c335c7e859 255 Pfam PF07615 YKOF-related Family 55 132 2.9E-10 T 28-03-2018 IPR011522 Thiamin/hydroxymethyl pyrimidine-binding YkoF, putative CFK41_RS03065 c5998dbb545de8962cd5c4ad15bfc8fb 303 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS03065 c5998dbb545de8962cd5c4ad15bfc8fb 303 Gene3D G3DSA:3.40.50.300 19 251 2.6E-59 T 28-03-2018 CFK41_RS03065 c5998dbb545de8962cd5c4ad15bfc8fb 303 Pfam PF00005 ABC transporter 41 179 1.0E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS03065 c5998dbb545de8962cd5c4ad15bfc8fb 303 SUPERFAMILY SSF52540 23 227 5.58E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS03065 c5998dbb545de8962cd5c4ad15bfc8fb 303 SMART SM00382 50 247 1.1E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS14360 bc35287f1128b3cc35aab023641a5b01 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 287 2.0E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS14360 bc35287f1128b3cc35aab023641a5b01 294 SUPERFAMILY SSF161098 13 294 6.64E-53 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS14360 bc35287f1128b3cc35aab023641a5b01 294 Gene3D G3DSA:1.10.3720.10 68 289 3.2E-33 T 28-03-2018 CFK41_RS15395 73fffff19fca32c4105643a4235f2a86 507 Gene3D G3DSA:1.20.1250.20 13 220 1.3E-20 T 28-03-2018 CFK41_RS15395 73fffff19fca32c4105643a4235f2a86 507 Pfam PF07690 Major Facilitator Superfamily 30 388 4.3E-30 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS15395 73fffff19fca32c4105643a4235f2a86 507 Gene3D G3DSA:1.20.1250.20 235 444 1.8E-19 T 28-03-2018 CFK41_RS15395 73fffff19fca32c4105643a4235f2a86 507 SUPERFAMILY SSF103473 14 433 9.42E-49 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS11180 b573c3de97f07c94f8a2a8ef32d7796a 227 SUPERFAMILY SSF56784 14 205 1.34E-24 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS11180 b573c3de97f07c94f8a2a8ef32d7796a 227 Gene3D G3DSA:3.40.50.1000 1 221 3.1E-19 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS11180 b573c3de97f07c94f8a2a8ef32d7796a 227 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 96 197 9.7E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CFK41_RS11180 b573c3de97f07c94f8a2a8ef32d7796a 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 81 197 2.4E-7 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS17095 2f3ee9a34a1bff3f7f3c5aa3fb8d6b90 432 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 299 305 - T 28-03-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 CFK41_RS17095 2f3ee9a34a1bff3f7f3c5aa3fb8d6b90 432 SUPERFAMILY SSF51395 30 220 2.32E-93 T 28-03-2018 CFK41_RS17095 2f3ee9a34a1bff3f7f3c5aa3fb8d6b90 432 SUPERFAMILY SSF51395 249 399 2.32E-93 T 28-03-2018 CFK41_RS17095 2f3ee9a34a1bff3f7f3c5aa3fb8d6b90 432 Pfam PF01070 FMN-dependent dehydrogenase 39 401 1.2E-121 T 28-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 CFK41_RS17095 2f3ee9a34a1bff3f7f3c5aa3fb8d6b90 432 Gene3D G3DSA:3.20.20.70 29 406 6.3E-94 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS17095 2f3ee9a34a1bff3f7f3c5aa3fb8d6b90 432 PIRSF PIRSF000138 21 408 9.6E-117 T 28-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CFK41_RS06015 847886edb20a0c356360f000fc45c9e9 413 SUPERFAMILY SSF53187 321 406 4.79E-63 T 28-03-2018 CFK41_RS06015 847886edb20a0c356360f000fc45c9e9 413 SUPERFAMILY SSF53187 25 220 4.79E-63 T 28-03-2018 CFK41_RS06015 847886edb20a0c356360f000fc45c9e9 413 PIRSF PIRSF005962 22 411 1.7E-92 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CFK41_RS06015 847886edb20a0c356360f000fc45c9e9 413 Pfam PF07687 Peptidase dimerisation domain 193 304 4.2E-10 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CFK41_RS06015 847886edb20a0c356360f000fc45c9e9 413 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 35 397 3.2E-92 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CFK41_RS06015 847886edb20a0c356360f000fc45c9e9 413 Gene3D G3DSA:3.40.630.10 270 409 7.8E-18 T 28-03-2018 CFK41_RS06015 847886edb20a0c356360f000fc45c9e9 413 Gene3D G3DSA:3.40.630.10 12 269 1.2E-40 T 28-03-2018 CFK41_RS06015 847886edb20a0c356360f000fc45c9e9 413 Pfam PF01546 Peptidase family M20/M25/M40 93 405 3.2E-25 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CFK41_RS06015 847886edb20a0c356360f000fc45c9e9 413 SUPERFAMILY SSF55031 208 319 1.09E-21 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CFK41_RS15370 d33df6e97522fcb69cc021153dad51e1 228 SUPERFAMILY SSF46785 152 217 2.72E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS15370 d33df6e97522fcb69cc021153dad51e1 228 SUPERFAMILY SSF55811 31 148 2.44E-25 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CFK41_RS15370 d33df6e97522fcb69cc021153dad51e1 228 Gene3D G3DSA:3.90.79.10 3 151 8.4E-31 T 28-03-2018 CFK41_RS15370 d33df6e97522fcb69cc021153dad51e1 228 Pfam PF00293 NUDIX domain 31 125 6.7E-8 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CFK41_RS15370 d33df6e97522fcb69cc021153dad51e1 228 Gene3D G3DSA:1.10.10.10 152 219 4.1E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS06160 a1d2cf8147142dc049c18d72eb2b32a2 254 SUPERFAMILY SSF53448 1 218 1.93E-48 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS06160 a1d2cf8147142dc049c18d72eb2b32a2 254 Gene3D G3DSA:3.90.550.10 1 239 6.4E-43 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS06160 a1d2cf8147142dc049c18d72eb2b32a2 254 Pfam PF00535 Glycosyl transferase family 2 2 117 6.1E-35 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CFK41_RS05035 bd16214fefe7941705538ba16fb10b87 337 Pfam PF02401 LytB protein 9 283 8.5E-91 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CFK41_RS05035 bd16214fefe7941705538ba16fb10b87 337 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 9 285 8.6E-101 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CFK41_RS05035 bd16214fefe7941705538ba16fb10b87 337 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 7 290 37.231 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CFK41_RS14315 ce01a510dd75d609f0a1c056bb957c82 251 Gene3D G3DSA:3.60.21.10 4 240 2.0E-20 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CFK41_RS14315 ce01a510dd75d609f0a1c056bb957c82 251 SUPERFAMILY SSF56300 8 236 7.12E-20 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CFK41_RS14315 ce01a510dd75d609f0a1c056bb957c82 251 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 12 220 1.4E-8 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CFK41_RS03515 06122c3837693d617d98498c4fb45ec2 282 SUPERFAMILY SSF51735 3 248 7.9E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS03515 06122c3837693d617d98498c4fb45ec2 282 Pfam PF00106 short chain dehydrogenase 4 189 2.2E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03515 06122c3837693d617d98498c4fb45ec2 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 2.3E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03515 06122c3837693d617d98498c4fb45ec2 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.3E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03515 06122c3837693d617d98498c4fb45ec2 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 2.3E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03515 06122c3837693d617d98498c4fb45ec2 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 2.3E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03515 06122c3837693d617d98498c4fb45ec2 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 2.3E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03515 06122c3837693d617d98498c4fb45ec2 282 PIRSF PIRSF000126 1 265 1.3E-59 T 28-03-2018 CFK41_RS03515 06122c3837693d617d98498c4fb45ec2 282 Gene3D G3DSA:3.40.50.720 2 279 1.6E-45 T 28-03-2018 CFK41_RS03515 06122c3837693d617d98498c4fb45ec2 282 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 6.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03515 06122c3837693d617d98498c4fb45ec2 282 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 6.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03515 06122c3837693d617d98498c4fb45ec2 282 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 6.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS08450 dd6d1c1bd7e062f66761a0ba2a229a20 295 SUPERFAMILY SSF55920 50 293 1.44E-75 T 28-03-2018 IPR000994 Peptidase M24 CFK41_RS08450 dd6d1c1bd7e062f66761a0ba2a229a20 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 237 249 3.7E-18 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CFK41_RS08450 dd6d1c1bd7e062f66761a0ba2a229a20 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 113 126 3.7E-18 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CFK41_RS08450 dd6d1c1bd7e062f66761a0ba2a229a20 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 135 151 3.7E-18 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CFK41_RS08450 dd6d1c1bd7e062f66761a0ba2a229a20 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 205 217 3.7E-18 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CFK41_RS08450 dd6d1c1bd7e062f66761a0ba2a229a20 295 Gene3D G3DSA:3.90.230.10 39 295 8.4E-77 T 28-03-2018 CFK41_RS08450 dd6d1c1bd7e062f66761a0ba2a229a20 295 Pfam PF00557 Metallopeptidase family M24 58 286 3.4E-46 T 28-03-2018 IPR000994 Peptidase M24 CFK41_RS08450 dd6d1c1bd7e062f66761a0ba2a229a20 295 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 50 293 2.1E-79 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CFK41_RS08450 dd6d1c1bd7e062f66761a0ba2a229a20 295 Hamap MF_01974 Methionine aminopeptidase [map]. 48 295 36.53 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CFK41_RS09825 dbe57a1d16b1445dbf6a11a684791ec4 602 Gene3D G3DSA:2.30.38.10 387 459 2.7E-20 T 28-03-2018 CFK41_RS09825 dbe57a1d16b1445dbf6a11a684791ec4 602 Gene3D G3DSA:3.40.50.980 191 386 1.9E-39 T 28-03-2018 CFK41_RS09825 dbe57a1d16b1445dbf6a11a684791ec4 602 ProSitePatterns PS00455 Putative AMP-binding domain signature. 184 195 - T 28-03-2018 IPR020845 AMP-binding, conserved site CFK41_RS09825 dbe57a1d16b1445dbf6a11a684791ec4 602 Pfam PF00501 AMP-binding enzyme 41 466 1.8E-90 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CFK41_RS09825 dbe57a1d16b1445dbf6a11a684791ec4 602 SUPERFAMILY SSF56801 17 289 3.01E-115 T 28-03-2018 CFK41_RS09825 dbe57a1d16b1445dbf6a11a684791ec4 602 SUPERFAMILY SSF56801 337 596 3.01E-115 T 28-03-2018 CFK41_RS09825 dbe57a1d16b1445dbf6a11a684791ec4 602 Gene3D G3DSA:3.30.300.30 461 597 2.1E-16 T 28-03-2018 CFK41_RS09825 dbe57a1d16b1445dbf6a11a684791ec4 602 Gene3D G3DSA:3.40.50.980 14 190 3.9E-34 T 28-03-2018 CFK41_RS07010 f76274a88b53b7152574b46635d09bb2 378 Gene3D G3DSA:1.20.58.410 8 100 2.0E-15 T 28-03-2018 CFK41_RS07010 f76274a88b53b7152574b46635d09bb2 378 SUPERFAMILY SSF75620 14 362 4.58E-114 T 28-03-2018 CFK41_RS07010 f76274a88b53b7152574b46635d09bb2 378 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 241 257 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CFK41_RS07010 f76274a88b53b7152574b46635d09bb2 378 Gene3D G3DSA:3.30.160.20 228 329 2.0E-29 T 28-03-2018 CFK41_RS07010 f76274a88b53b7152574b46635d09bb2 378 Pfam PF00472 RF-1 domain 230 334 1.4E-36 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CFK41_RS07010 f76274a88b53b7152574b46635d09bb2 378 SMART SM00937 68 186 3.4E-39 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CFK41_RS07010 f76274a88b53b7152574b46635d09bb2 378 Pfam PF03462 PCRF domain 16 211 1.5E-59 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CFK41_RS07010 f76274a88b53b7152574b46635d09bb2 378 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 9 369 2.1E-128 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CFK41_RS03090 b937c3802cc8550e1fa7c1f40b1560ef 432 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 189 203 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CFK41_RS03090 b937c3802cc8550e1fa7c1f40b1560ef 432 SUPERFAMILY SSF53383 1 424 1.13E-112 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS03090 b937c3802cc8550e1fa7c1f40b1560ef 432 PIRSF PIRSF001434 1 428 4.0E-113 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CFK41_RS03090 b937c3802cc8550e1fa7c1f40b1560ef 432 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 1 424 1.5E-123 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CFK41_RS03090 b937c3802cc8550e1fa7c1f40b1560ef 432 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 1 424 5.5E-170 T 28-03-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 CFK41_RS03090 b937c3802cc8550e1fa7c1f40b1560ef 432 Gene3D G3DSA:3.90.1150.10 280 432 3.7E-40 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS03090 b937c3802cc8550e1fa7c1f40b1560ef 432 Gene3D G3DSA:3.40.640.10 1 278 2.3E-62 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS05095 8a3c7004216068ed977d5dee7c901156 229 Gene3D G3DSA:1.10.357.10 57 193 2.2E-15 T 28-03-2018 CFK41_RS05095 8a3c7004216068ed977d5dee7c901156 229 SUPERFAMILY SSF48498 82 146 4.89E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CFK41_RS05095 8a3c7004216068ed977d5dee7c901156 229 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 1.3E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS05095 8a3c7004216068ed977d5dee7c901156 229 Gene3D G3DSA:1.10.10.60 7 56 1.3E-17 T 28-03-2018 CFK41_RS05095 8a3c7004216068ed977d5dee7c901156 229 SUPERFAMILY SSF46689 7 76 1.04E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS03875 096a635930d193f60f5417bcec52f711 121 Pfam PF06262 Zincin-like metallopeptidase 31 120 2.5E-30 T 28-03-2018 IPR010428 Zincin-like metallopeptidase CFK41_RS03875 096a635930d193f60f5417bcec52f711 121 SUPERFAMILY SSF55486 1 120 3.08E-35 T 28-03-2018 CFK41_RS03455 e13f2b1ca0346e64711ce5f9ba27d6a9 448 Pfam PF01547 Bacterial extracellular solute-binding protein 62 340 3.0E-20 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CFK41_RS03455 e13f2b1ca0346e64711ce5f9ba27d6a9 448 SUPERFAMILY SSF53850 52 446 3.69E-43 T 28-03-2018 CFK41_RS03455 e13f2b1ca0346e64711ce5f9ba27d6a9 448 Gene3D G3DSA:3.40.190.10 182 408 1.2E-22 T 28-03-2018 CFK41_RS03455 e13f2b1ca0346e64711ce5f9ba27d6a9 448 Gene3D G3DSA:3.40.190.10 53 181 9.9E-20 T 28-03-2018 CFK41_RS15810 1d0d9aa35b4b618e4f60d4ad6d3ab175 131 Gene3D G3DSA:3.40.50.2000 6 131 3.0E-15 T 28-03-2018 CFK41_RS15810 1d0d9aa35b4b618e4f60d4ad6d3ab175 131 Pfam PF08660 Oligosaccharide biosynthesis protein Alg14 like 41 128 1.9E-10 T 28-03-2018 IPR013969 Oligosaccharide biosynthesis protein Alg14-like GO:0006488 Reactome: R-HSA-446193 CFK41_RS15810 1d0d9aa35b4b618e4f60d4ad6d3ab175 131 SUPERFAMILY SSF53756 39 125 1.26E-6 T 28-03-2018 CFK41_RS14685 5f16f9e65b5ff64125998c955e8372a1 333 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 126 324 8.2E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS14685 5f16f9e65b5ff64125998c955e8372a1 333 SUPERFAMILY SSF160964 46 81 5.62E-5 T 28-03-2018 CFK41_RS14685 5f16f9e65b5ff64125998c955e8372a1 333 Gene3D G3DSA:1.10.3720.10 100 331 1.7E-44 T 28-03-2018 CFK41_RS14685 5f16f9e65b5ff64125998c955e8372a1 333 SUPERFAMILY SSF161098 93 320 1.57E-56 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS14685 5f16f9e65b5ff64125998c955e8372a1 333 Gene3D G3DSA:1.20.58.370 33 80 4.0E-6 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CFK41_RS04635 422f73c42d8200fbdde14dac73a86cae 122 SUPERFAMILY SSF50193 2 122 2.22E-50 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CFK41_RS04635 422f73c42d8200fbdde14dac73a86cae 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 2.9E-57 T 28-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 CFK41_RS04635 422f73c42d8200fbdde14dac73a86cae 122 Pfam PF00238 Ribosomal protein L14p/L23e 2 122 1.8E-54 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CFK41_RS04635 422f73c42d8200fbdde14dac73a86cae 122 SMART SM01374 1 122 2.1E-85 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CFK41_RS04635 422f73c42d8200fbdde14dac73a86cae 122 Gene3D G3DSA:2.40.150.20 1 122 3.2E-53 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CFK41_RS04635 422f73c42d8200fbdde14dac73a86cae 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.116 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CFK41_RS04635 422f73c42d8200fbdde14dac73a86cae 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 28-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS06700 66758ee40bdbaf5882b53a88942fc700 358 Gene3D G3DSA:3.20.20.70 1 358 8.4E-113 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS06700 66758ee40bdbaf5882b53a88942fc700 358 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 6 334 6.0E-79 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CFK41_RS06700 66758ee40bdbaf5882b53a88942fc700 358 SUPERFAMILY SSF51395 2 356 3.1E-109 T 28-03-2018 CFK41_RS08490 d205d389cbe9b8364d551553c30e0ae6 113 Gene3D G3DSA:3.30.70.1060 1 113 6.7E-20 T 28-03-2018 CFK41_RS08490 d205d389cbe9b8364d551553c30e0ae6 113 SUPERFAMILY SSF54909 9 109 8.85E-15 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CFK41_RS08490 d205d389cbe9b8364d551553c30e0ae6 113 Pfam PF03795 YCII-related domain 21 95 5.1E-7 T 28-03-2018 IPR005545 YCII-related CFK41_RS05315 71a8c533a346238da78b3ea7b7b82663 146 Gene3D G3DSA:3.30.160.20 13 146 2.9E-32 T 28-03-2018 CFK41_RS05315 71a8c533a346238da78b3ea7b7b82663 146 SUPERFAMILY SSF75620 6 108 2.98E-11 T 28-03-2018 CFK41_RS05315 71a8c533a346238da78b3ea7b7b82663 146 Pfam PF00472 RF-1 domain 17 140 5.7E-20 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CFK41_RS07350 80b42ba8a6e15bf6d01ede27c6e84284 244 Pfam PF01614 Bacterial transcriptional regulator 132 235 6.8E-15 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CFK41_RS07350 80b42ba8a6e15bf6d01ede27c6e84284 244 SMART SM00346 12 98 1.1E-17 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CFK41_RS07350 80b42ba8a6e15bf6d01ede27c6e84284 244 SUPERFAMILY SSF46785 13 80 6.07E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS07350 80b42ba8a6e15bf6d01ede27c6e84284 244 Gene3D G3DSA:1.10.10.10 6 70 3.8E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS07350 80b42ba8a6e15bf6d01ede27c6e84284 244 SUPERFAMILY SSF55781 67 239 5.56E-32 T 28-03-2018 IPR029016 GAF domain-like CFK41_RS07350 80b42ba8a6e15bf6d01ede27c6e84284 244 Gene3D G3DSA:3.30.450.40 77 244 2.0E-32 T 28-03-2018 IPR029016 GAF domain-like CFK41_RS07350 80b42ba8a6e15bf6d01ede27c6e84284 244 Pfam PF09339 IclR helix-turn-helix domain 15 62 1.5E-8 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CFK41_RS04820 7294e1dc65993a6643ed24b82c58bf6b 348 SUPERFAMILY SSF51182 20 286 1.42E-58 T 28-03-2018 IPR011051 RmlC-like cupin domain CFK41_RS04820 7294e1dc65993a6643ed24b82c58bf6b 348 Pfam PF02678 Pirin 25 123 2.8E-29 T 28-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 CFK41_RS04820 7294e1dc65993a6643ed24b82c58bf6b 348 PIRSF PIRSF006232 7 297 3.1E-65 T 28-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 CFK41_RS04820 7294e1dc65993a6643ed24b82c58bf6b 348 Pfam PF05726 Pirin C-terminal cupin domain 183 286 1.8E-16 T 28-03-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 CFK41_RS04820 7294e1dc65993a6643ed24b82c58bf6b 348 Gene3D G3DSA:2.60.120.10 16 263 1.7E-53 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CFK41_RS05155 ff5c416bf819cf35fce4cba3b71ead35 441 SUPERFAMILY SSF51679 9 431 2.62E-94 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CFK41_RS05155 ff5c416bf819cf35fce4cba3b71ead35 441 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 12 427 1.1E-104 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CFK41_RS05155 ff5c416bf819cf35fce4cba3b71ead35 441 PIRSF PIRSF000337 2 438 4.1E-110 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CFK41_RS05155 ff5c416bf819cf35fce4cba3b71ead35 441 Gene3D G3DSA:3.20.20.30 2 438 7.7E-81 T 28-03-2018 CFK41_RS05155 ff5c416bf819cf35fce4cba3b71ead35 441 Pfam PF00296 Luciferase-like monooxygenase 31 383 1.2E-47 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CFK41_RS14675 2569a4362a60365f8c2505c0143f35a6 357 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 143 316 3.1E-54 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CFK41_RS14675 2569a4362a60365f8c2505c0143f35a6 357 SUPERFAMILY SSF51735 134 317 5.61E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS14675 2569a4362a60365f8c2505c0143f35a6 357 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 57 345 1.5E-25 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CFK41_RS14675 2569a4362a60365f8c2505c0143f35a6 357 Gene3D G3DSA:3.40.50.720 37 143 3.3E-30 T 28-03-2018 CFK41_RS14675 2569a4362a60365f8c2505c0143f35a6 357 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 255 271 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CFK41_RS14675 2569a4362a60365f8c2505c0143f35a6 357 Gene3D G3DSA:3.40.50.720 144 318 8.3E-56 T 28-03-2018 CFK41_RS14675 2569a4362a60365f8c2505c0143f35a6 357 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 226 248 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CFK41_RS14675 2569a4362a60365f8c2505c0143f35a6 357 SUPERFAMILY SSF52283 47 168 2.84E-31 T 28-03-2018 CFK41_RS17580 4e114948fc694cb1b3199a1274229698 157 ProSitePatterns PS00651 Ribosomal protein L9 signature. 15 42 - T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS17580 4e114948fc694cb1b3199a1274229698 157 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 3 150 24.334 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS17580 4e114948fc694cb1b3199a1274229698 157 SUPERFAMILY SSF55653 59 149 4.71E-23 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CFK41_RS17580 4e114948fc694cb1b3199a1274229698 157 Gene3D G3DSA:3.10.430.100 65 149 1.1E-23 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CFK41_RS17580 4e114948fc694cb1b3199a1274229698 157 Pfam PF01281 Ribosomal protein L9, N-terminal domain 4 47 4.0E-19 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS17580 4e114948fc694cb1b3199a1274229698 157 SUPERFAMILY SSF55658 4 56 3.84E-16 T 28-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal CFK41_RS17580 4e114948fc694cb1b3199a1274229698 157 TIGRFAM TIGR00158 L9: ribosomal protein bL9 4 149 4.4E-39 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS17580 4e114948fc694cb1b3199a1274229698 157 Gene3D G3DSA:3.40.5.10 4 52 3.0E-19 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS17580 4e114948fc694cb1b3199a1274229698 157 Pfam PF03948 Ribosomal protein L9, C-terminal domain 65 149 3.6E-23 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CFK41_RS10795 99ac0ec98406f523f8a367fbb08e088f 348 Pfam PF00356 Bacterial regulatory proteins, lacI family 14 53 1.3E-13 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS10795 99ac0ec98406f523f8a367fbb08e088f 348 Gene3D G3DSA:3.40.50.2300 77 176 7.6E-20 T 28-03-2018 CFK41_RS10795 99ac0ec98406f523f8a367fbb08e088f 348 Gene3D G3DSA:3.40.50.2300 177 339 2.7E-37 T 28-03-2018 CFK41_RS10795 99ac0ec98406f523f8a367fbb08e088f 348 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 12 22 4.4E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS10795 99ac0ec98406f523f8a367fbb08e088f 348 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 22 32 4.4E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS10795 99ac0ec98406f523f8a367fbb08e088f 348 SMART SM00354 10 76 1.3E-16 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS10795 99ac0ec98406f523f8a367fbb08e088f 348 Pfam PF13377 Periplasmic binding protein-like domain 179 336 5.4E-31 T 28-03-2018 CFK41_RS10795 99ac0ec98406f523f8a367fbb08e088f 348 ProSitePatterns PS00356 LacI-type HTH domain signature. 13 31 - T 28-03-2018 CFK41_RS10795 99ac0ec98406f523f8a367fbb08e088f 348 SUPERFAMILY SSF53822 66 340 1.18E-55 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS10795 99ac0ec98406f523f8a367fbb08e088f 348 Gene3D G3DSA:1.10.260.40 27 76 2.9E-17 T 28-03-2018 CFK41_RS10795 99ac0ec98406f523f8a367fbb08e088f 348 Gene3D G3DSA:1.10.10.60 7 26 0.0029 T 28-03-2018 CFK41_RS10795 99ac0ec98406f523f8a367fbb08e088f 348 SUPERFAMILY SSF47413 10 56 1.09E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS12665 52571efabfa972a280376147b5fa82e7 436 SMART SM00450 323 429 4.7E-8 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS12665 52571efabfa972a280376147b5fa82e7 436 Pfam PF00581 Rhodanese-like domain 328 423 1.7E-7 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS12665 52571efabfa972a280376147b5fa82e7 436 SUPERFAMILY SSF52821 319 427 7.96E-17 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS12665 52571efabfa972a280376147b5fa82e7 436 Pfam PF00899 ThiF family 63 296 9.9E-63 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CFK41_RS12665 52571efabfa972a280376147b5fa82e7 436 SUPERFAMILY SSF69572 60 297 2.09E-81 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CFK41_RS12665 52571efabfa972a280376147b5fa82e7 436 Gene3D G3DSA:3.40.50.720 57 298 9.2E-68 T 28-03-2018 CFK41_RS12665 52571efabfa972a280376147b5fa82e7 436 Gene3D G3DSA:3.40.250.10 316 435 2.2E-16 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS12155 8c823d7b459af1c51dca6f7b43d848b5 272 Gene3D G3DSA:3.90.1720.10 156 266 4.8E-36 T 28-03-2018 CFK41_RS12155 8c823d7b459af1c51dca6f7b43d848b5 272 SUPERFAMILY SSF47090 79 144 1.2E-17 T 28-03-2018 IPR002477 Peptidoglycan binding-like CFK41_RS12155 8c823d7b459af1c51dca6f7b43d848b5 272 Pfam PF01471 Putative peptidoglycan binding domain 89 143 5.3E-14 T 28-03-2018 IPR002477 Peptidoglycan binding-like CFK41_RS12155 8c823d7b459af1c51dca6f7b43d848b5 272 Pfam PF00877 NlpC/P60 family 176 257 5.5E-24 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CFK41_RS12155 8c823d7b459af1c51dca6f7b43d848b5 272 Gene3D G3DSA:1.20.141.10 114 155 1.6E-12 T 28-03-2018 CFK41_RS12155 8c823d7b459af1c51dca6f7b43d848b5 272 Gene3D G3DSA:1.20.141.10 39 113 8.2E-9 T 28-03-2018 CFK41_RS12155 8c823d7b459af1c51dca6f7b43d848b5 272 SUPERFAMILY SSF54001 156 262 7.85E-38 T 28-03-2018 CFK41_RS12065 c951b214e83ca41404f99d2e95ac68de 361 Gene3D G3DSA:3.30.390.50 7 99 4.6E-25 T 28-03-2018 CFK41_RS12065 c951b214e83ca41404f99d2e95ac68de 361 Pfam PF03099 Biotin/lipoate A/B protein ligase family 166 275 2.4E-7 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CFK41_RS12065 c951b214e83ca41404f99d2e95ac68de 361 SUPERFAMILY SSF55681 111 357 6.96E-63 T 28-03-2018 CFK41_RS12065 c951b214e83ca41404f99d2e95ac68de 361 Gene3D G3DSA:3.30.930.10 100 353 3.0E-49 T 28-03-2018 CFK41_RS05670 bd60f066fabe0e9df92d009b0a1fd905 273 Pfam PF07179 SseB protein N-terminal domain 57 168 1.7E-26 T 28-03-2018 IPR009839 SseB protein N-terminal domain CFK41_RS05670 bd60f066fabe0e9df92d009b0a1fd905 273 Gene3D G3DSA:3.30.70.1350 192 264 3.3E-4 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CFK41_RS17465 fb41ce144abe9448896a3b996fd2f898 419 ProSitePatterns PS00618 RecF protein signature 2. 354 372 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CFK41_RS17465 fb41ce144abe9448896a3b996fd2f898 419 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 2 398 6.9E-101 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CFK41_RS17465 fb41ce144abe9448896a3b996fd2f898 419 Gene3D G3DSA:3.40.50.300 2 417 2.1E-29 T 28-03-2018 CFK41_RS17465 fb41ce144abe9448896a3b996fd2f898 419 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 389 1.1E-18 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CFK41_RS17465 fb41ce144abe9448896a3b996fd2f898 419 SUPERFAMILY SSF52540 3 232 1.3E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS17465 fb41ce144abe9448896a3b996fd2f898 419 SUPERFAMILY SSF52540 282 389 1.3E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS17465 fb41ce144abe9448896a3b996fd2f898 419 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 419 83.848 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CFK41_RS07985 36b4bb274c56051d9c2fd67f4b1917fa 385 Gene3D G3DSA:1.10.10.10 293 367 9.3E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS07985 36b4bb274c56051d9c2fd67f4b1917fa 385 SUPERFAMILY SSF140931 122 283 1.07E-30 T 28-03-2018 IPR003812 Fido domain CFK41_RS07985 36b4bb274c56051d9c2fd67f4b1917fa 385 Pfam PF02661 Fic/DOC family 131 231 1.6E-22 T 28-03-2018 IPR003812 Fido domain CFK41_RS07985 36b4bb274c56051d9c2fd67f4b1917fa 385 Gene3D G3DSA:1.10.3290.10 43 292 3.3E-42 T 28-03-2018 IPR003812 Fido domain CFK41_RS13285 430295c9a28516913ef24fc36fb48e0b 338 Gene3D G3DSA:3.20.20.100 18 334 1.1E-84 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS13285 430295c9a28516913ef24fc36fb48e0b 338 Pfam PF00248 Aldo/keto reductase family 30 331 1.2E-66 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS13285 430295c9a28516913ef24fc36fb48e0b 338 SUPERFAMILY SSF51430 18 332 2.75E-85 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS13710 a85e16ee538c4ddd46eacc8571ec4f4f 304 Gene3D G3DSA:3.30.530.20 165 303 1.2E-23 T 28-03-2018 IPR023393 START-like domain CFK41_RS13710 a85e16ee538c4ddd46eacc8571ec4f4f 304 SUPERFAMILY SSF55961 10 141 1.79E-13 T 28-03-2018 CFK41_RS13710 a85e16ee538c4ddd46eacc8571ec4f4f 304 Gene3D G3DSA:3.30.530.20 1 164 8.2E-15 T 28-03-2018 IPR023393 START-like domain CFK41_RS13710 a85e16ee538c4ddd46eacc8571ec4f4f 304 SUPERFAMILY SSF55961 165 303 6.52E-26 T 28-03-2018 CFK41_RS13710 a85e16ee538c4ddd46eacc8571ec4f4f 304 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 175 302 4.7E-22 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CFK41_RS13380 6adea2f5fc213a059b776bdbad8dec6e 756 Pfam PF05592 Bacterial alpha-L-rhamnosidase concanavalin-like domain 225 328 4.7E-11 T 28-03-2018 IPR008902 Alpha-L-rhamnosidase, concanavalin-like domain CFK41_RS13380 6adea2f5fc213a059b776bdbad8dec6e 756 Gene3D G3DSA:1.50.10.10 333 673 8.7E-29 T 28-03-2018 CFK41_RS13380 6adea2f5fc213a059b776bdbad8dec6e 756 Gene3D G3DSA:2.60.120.260 206 331 5.2E-20 T 28-03-2018 IPR008979 Galactose-binding domain-like CFK41_RS13380 6adea2f5fc213a059b776bdbad8dec6e 756 SUPERFAMILY SSF48208 327 742 1.19E-27 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CFK41_RS13380 6adea2f5fc213a059b776bdbad8dec6e 756 Gene3D G3DSA:2.60.420.10 674 747 9.2E-12 T 28-03-2018 CFK41_RS13380 6adea2f5fc213a059b776bdbad8dec6e 756 Pfam PF17389 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain 335 677 3.2E-60 T 28-03-2018 IPR035396 Alpha-L-rhamnosidase, six-hairpin glycosidase domain CFK41_RS13380 6adea2f5fc213a059b776bdbad8dec6e 756 Pfam PF17390 Bacterial alpha-L-rhamnosidase C-terminal domain 680 753 6.2E-10 T 28-03-2018 IPR035398 Alpha-L-rhamnosidase C-terminal domain CFK41_RS13380 6adea2f5fc213a059b776bdbad8dec6e 756 Gene3D G3DSA:2.60.120.260 4 194 8.2E-36 T 28-03-2018 IPR008979 Galactose-binding domain-like CFK41_RS13380 6adea2f5fc213a059b776bdbad8dec6e 756 Pfam PF08531 Alpha-L-rhamnosidase N-terminal domain 38 210 3.8E-32 T 28-03-2018 IPR013737 Bacterial alpha-L-rhamnosidase N-terminal CFK41_RS09805 efaa04fabf657af41dc545d8f2dac9e1 244 SUPERFAMILY SSF69593 9 220 3.4E-46 T 28-03-2018 CFK41_RS09805 efaa04fabf657af41dc545d8f2dac9e1 244 SMART SM00563 34 153 4.6E-29 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CFK41_RS09805 efaa04fabf657af41dc545d8f2dac9e1 244 Pfam PF01553 Acyltransferase 21 150 3.3E-23 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CFK41_RS09805 efaa04fabf657af41dc545d8f2dac9e1 244 Gene3D G3DSA:3.40.1130.10 4 233 8.3E-46 T 28-03-2018 CFK41_RS07705 3c56b62998148995c97419511a941eb2 333 Pfam PF00294 pfkB family carbohydrate kinase 6 296 1.3E-41 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CFK41_RS07705 3c56b62998148995c97419511a941eb2 333 SUPERFAMILY SSF53613 5 298 2.49E-56 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS07705 3c56b62998148995c97419511a941eb2 333 Gene3D G3DSA:3.40.1190.20 5 306 2.6E-50 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS07705 3c56b62998148995c97419511a941eb2 333 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 237 250 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CFK41_RS07705 3c56b62998148995c97419511a941eb2 333 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 29 53 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CFK41_RS09995 434152b1fbaf2d9a5b2fc86fa88e8fe5 624 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 34 543 2.7E-165 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CFK41_RS09995 434152b1fbaf2d9a5b2fc86fa88e8fe5 624 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 72 543 1.8E-143 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CFK41_RS15875 6d073494fd4af4141922c40cfb39f035 355 Pfam PF06737 Transglycosylase-like domain 51 126 4.2E-34 T 28-03-2018 IPR010618 Transglycosylase-like CFK41_RS15875 6d073494fd4af4141922c40cfb39f035 355 Gene3D G3DSA:1.10.530.10 26 133 6.5E-31 T 28-03-2018 CFK41_RS15875 6d073494fd4af4141922c40cfb39f035 355 SUPERFAMILY SSF53955 51 132 1.33E-32 T 28-03-2018 IPR023346 Lysozyme-like domain CFK41_RS15875 6d073494fd4af4141922c40cfb39f035 355 Gene3D G3DSA:1.20.141.10 293 355 3.4E-4 T 28-03-2018 CFK41_RS15875 6d073494fd4af4141922c40cfb39f035 355 Gene3D G3DSA:1.20.141.10 182 224 7.9E-4 T 28-03-2018 CFK41_RS15875 6d073494fd4af4141922c40cfb39f035 355 Gene3D G3DSA:1.20.141.10 225 292 1.3E-5 T 28-03-2018 CFK41_RS12965 9ccb6bf464bc59c574d1bc8f1ff6f03d 323 Gene3D G3DSA:3.30.420.10 1 142 2.8E-41 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CFK41_RS12965 9ccb6bf464bc59c574d1bc8f1ff6f03d 323 Hamap MF_00042 Ribonuclease H [rnhA]. 1 147 26.207 T 28-03-2018 IPR022892 Ribonuclease HI GO:0004523 CFK41_RS12965 9ccb6bf464bc59c574d1bc8f1ff6f03d 323 Pfam PF14534 Domain of unknown function (DUF4440) 217 310 4.9E-10 T 28-03-2018 IPR027843 Domain of unknown function DUF4440 CFK41_RS12965 9ccb6bf464bc59c574d1bc8f1ff6f03d 323 SUPERFAMILY SSF53098 3 139 3.41E-40 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CFK41_RS12965 9ccb6bf464bc59c574d1bc8f1ff6f03d 323 SUPERFAMILY SSF54427 212 318 6.58E-13 T 28-03-2018 IPR032710 NTF2-like domain CFK41_RS12965 9ccb6bf464bc59c574d1bc8f1ff6f03d 323 Gene3D G3DSA:3.10.450.50 213 318 5.6E-23 T 28-03-2018 CFK41_RS12965 9ccb6bf464bc59c574d1bc8f1ff6f03d 323 Pfam PF00075 RNase H 6 138 2.5E-29 T 28-03-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 CFK41_RS08140 9bb439fada89659632aaca52464363d3 336 Gene3D G3DSA:3.30.450.40 191 336 9.1E-30 T 28-03-2018 IPR029016 GAF domain-like CFK41_RS08140 9bb439fada89659632aaca52464363d3 336 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 3 328 24.744 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CFK41_RS08140 9bb439fada89659632aaca52464363d3 336 Pfam PF08220 DeoR-like helix-turn-helix domain 36 64 3.7E-5 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CFK41_RS08140 9bb439fada89659632aaca52464363d3 336 SUPERFAMILY SSF55781 73 335 5.49E-44 T 28-03-2018 IPR029016 GAF domain-like CFK41_RS08140 9bb439fada89659632aaca52464363d3 336 Pfam PF01628 HrcA protein C terminal domain 105 319 6.6E-51 T 28-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 CFK41_RS08140 9bb439fada89659632aaca52464363d3 336 SUPERFAMILY SSF46785 4 83 1.25E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS08140 9bb439fada89659632aaca52464363d3 336 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 6 334 3.8E-82 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CFK41_RS08140 9bb439fada89659632aaca52464363d3 336 Gene3D G3DSA:1.10.10.10 1 86 1.4E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS08140 9bb439fada89659632aaca52464363d3 336 PIRSF PIRSF005485 1 336 1.6E-89 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CFK41_RS07100 033127bea3ca1319edeb581478e85be9 299 Gene3D G3DSA:3.40.30.10 27 221 1.6E-20 T 28-03-2018 CFK41_RS07100 033127bea3ca1319edeb581478e85be9 299 SUPERFAMILY SSF48452 164 254 3.58E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CFK41_RS07100 033127bea3ca1319edeb581478e85be9 299 SUPERFAMILY SSF52833 32 139 4.25E-11 T 28-03-2018 IPR012336 Thioredoxin-like fold CFK41_RS07100 033127bea3ca1319edeb581478e85be9 299 Gene3D G3DSA:1.25.40.10 222 299 0.0091 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CFK41_RS07100 033127bea3ca1319edeb581478e85be9 299 Pfam PF14561 Tetratricopeptide repeat 211 299 2.1E-23 T 28-03-2018 CFK41_RS15745 284f013e185ff12433692adc00d1b258 584 SUPERFAMILY SSF52540 404 541 2.67E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS15745 284f013e185ff12433692adc00d1b258 584 Pfam PF00664 ABC transporter transmembrane region 60 277 1.3E-8 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS15745 284f013e185ff12433692adc00d1b258 584 SUPERFAMILY SSF90123 19 306 3.14E-28 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS15745 284f013e185ff12433692adc00d1b258 584 Gene3D G3DSA:1.20.1560.10 21 310 3.6E-19 T 28-03-2018 CFK41_RS15745 284f013e185ff12433692adc00d1b258 584 Gene3D G3DSA:3.40.50.300 416 563 1.3E-10 T 28-03-2018 CFK41_RS12815 0ce88f3b6c31b81f5b4ec69ca2370003 945 Gene3D G3DSA:2.60.40.1710 677 793 4.0E-19 T 28-03-2018 CFK41_RS12815 0ce88f3b6c31b81f5b4ec69ca2370003 945 Gene3D G3DSA:3.40.50.200 194 676 9.6E-88 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CFK41_RS12815 0ce88f3b6c31b81f5b4ec69ca2370003 945 Gene3D G3DSA:3.30.70.80 107 193 3.5E-5 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CFK41_RS12815 0ce88f3b6c31b81f5b4ec69ca2370003 945 SUPERFAMILY SSF52025 473 553 5.23E-10 T 28-03-2018 CFK41_RS12815 0ce88f3b6c31b81f5b4ec69ca2370003 945 SUPERFAMILY SSF52743 208 418 4.45E-80 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CFK41_RS12815 0ce88f3b6c31b81f5b4ec69ca2370003 945 SUPERFAMILY SSF52743 565 673 4.45E-80 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CFK41_RS12815 0ce88f3b6c31b81f5b4ec69ca2370003 945 Pfam PF00082 Subtilase family 225 663 2.3E-62 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CFK41_RS12815 0ce88f3b6c31b81f5b4ec69ca2370003 945 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 230 241 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CFK41_RS12815 0ce88f3b6c31b81f5b4ec69ca2370003 945 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 292 302 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CFK41_RS12815 0ce88f3b6c31b81f5b4ec69ca2370003 945 PRINTS PR00723 Subtilisin serine protease family (S8) signature 288 301 2.3E-21 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CFK41_RS12815 0ce88f3b6c31b81f5b4ec69ca2370003 945 PRINTS PR00723 Subtilisin serine protease family (S8) signature 604 620 2.3E-21 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CFK41_RS12815 0ce88f3b6c31b81f5b4ec69ca2370003 945 PRINTS PR00723 Subtilisin serine protease family (S8) signature 225 244 2.3E-21 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CFK41_RS12815 0ce88f3b6c31b81f5b4ec69ca2370003 945 Pfam PF02225 PA domain 445 536 2.5E-11 T 28-03-2018 IPR003137 PA domain CFK41_RS12815 0ce88f3b6c31b81f5b4ec69ca2370003 945 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 605 615 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CFK41_RS12815 0ce88f3b6c31b81f5b4ec69ca2370003 945 Pfam PF06280 Fn3-like domain 682 783 1.3E-9 T 28-03-2018 IPR010435 Fn3-like domain GO:0004252|GO:0005618|GO:0016020 CFK41_RS14235 cb5cf2dbc0d05eabcf63eefd12fe4449 316 SUPERFAMILY SSF161098 75 302 1.7E-60 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS14235 cb5cf2dbc0d05eabcf63eefd12fe4449 316 SUPERFAMILY SSF160964 30 93 2.35E-5 T 28-03-2018 CFK41_RS14235 cb5cf2dbc0d05eabcf63eefd12fe4449 316 Gene3D G3DSA:1.10.3720.10 23 304 4.0E-54 T 28-03-2018 CFK41_RS14235 cb5cf2dbc0d05eabcf63eefd12fe4449 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 306 1.1E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS00890 210db72ddc4515c402fbeae1afe43e3f 299 SMART SM00641 88 191 9.8E-18 T 28-03-2018 IPR018077 Glycoside hydrolase, family 25 subgroup CFK41_RS00890 210db72ddc4515c402fbeae1afe43e3f 299 ProSitePatterns PS00953 Glycosyl hydrolases family 25 active sites signature. 92 125 - T 28-03-2018 IPR008270 Glycoside hydrolase, family 25, active site GO:0003796|GO:0009253|GO:0016998 CFK41_RS00890 210db72ddc4515c402fbeae1afe43e3f 299 SUPERFAMILY SSF51445 88 272 3.72E-46 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS00890 210db72ddc4515c402fbeae1afe43e3f 299 Pfam PF01183 Glycosyl hydrolases family 25 91 261 3.9E-36 T 28-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 CFK41_RS00890 210db72ddc4515c402fbeae1afe43e3f 299 Gene3D G3DSA:3.20.20.80 79 281 3.0E-52 T 28-03-2018 CFK41_RS13705 296b31138218c95707e598b90196f5d9 262 Pfam PF08241 Methyltransferase domain 37 127 1.6E-15 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CFK41_RS13705 296b31138218c95707e598b90196f5d9 262 SUPERFAMILY SSF53335 32 261 1.13E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS13705 296b31138218c95707e598b90196f5d9 262 Gene3D G3DSA:3.40.50.150 18 262 2.4E-27 T 28-03-2018 CFK41_RS03805 694dd6bc36a1b8799e446ee47f582f9f 974 Pfam PF00361 Proton-conducting membrane transporter 122 405 5.6E-58 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CFK41_RS03805 694dd6bc36a1b8799e446ee47f582f9f 974 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 56 109 4.3E-9 T 28-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CFK41_RS03805 694dd6bc36a1b8799e446ee47f582f9f 974 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 830 952 1.4E-30 T 28-03-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein CFK41_RS03805 694dd6bc36a1b8799e446ee47f582f9f 974 Pfam PF13244 Domain of unknown function (DUF4040) 610 672 8.6E-18 T 28-03-2018 IPR025383 Domain of unknown function DUF4040 CFK41_RS03805 694dd6bc36a1b8799e446ee47f582f9f 974 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 212 233 4.1E-30 T 28-03-2018 CFK41_RS03805 694dd6bc36a1b8799e446ee47f582f9f 974 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 302 314 4.1E-30 T 28-03-2018 CFK41_RS03805 694dd6bc36a1b8799e446ee47f582f9f 974 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 408 427 4.1E-30 T 28-03-2018 CFK41_RS03805 694dd6bc36a1b8799e446ee47f582f9f 974 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 234 260 4.1E-30 T 28-03-2018 CFK41_RS03805 694dd6bc36a1b8799e446ee47f582f9f 974 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 70 95 4.1E-30 T 28-03-2018 CFK41_RS03805 694dd6bc36a1b8799e446ee47f582f9f 974 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 99 119 4.1E-30 T 28-03-2018 CFK41_RS09195 606c752df5cf5403fd02241979226342 371 PIRSF PIRSF036915 1 371 7.5E-162 T 28-03-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CFK41_RS09195 606c752df5cf5403fd02241979226342 371 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 17 361 1.0E-80 T 28-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CFK41_RS09195 606c752df5cf5403fd02241979226342 371 ProSitePatterns PS00958 Transaldolase active site. 139 156 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CFK41_RS09195 606c752df5cf5403fd02241979226342 371 Gene3D G3DSA:3.20.20.70 3 363 7.8E-122 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS09195 606c752df5cf5403fd02241979226342 371 ProSitePatterns PS01054 Transaldolase signature 1. 43 51 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CFK41_RS09195 606c752df5cf5403fd02241979226342 371 TIGRFAM TIGR00876 tal_mycobact: transaldolase 13 360 1.8E-133 T 28-03-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CFK41_RS09195 606c752df5cf5403fd02241979226342 371 Hamap MF_00493 Transaldolase [tal]. 1 371 144.602 T 28-03-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CFK41_RS09195 606c752df5cf5403fd02241979226342 371 SUPERFAMILY SSF51569 8 364 8.79E-72 T 28-03-2018 CFK41_RS03460 a6bfb4ac122a4a4871a0bdcc3e9a404a 909 SMART SM00437 281 552 9.7E-110 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CFK41_RS03460 a6bfb4ac122a4a4871a0bdcc3e9a404a 909 Gene3D G3DSA:3.40.50.140 4 150 7.5E-41 T 28-03-2018 CFK41_RS03460 a6bfb4ac122a4a4871a0bdcc3e9a404a 909 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 318 332 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CFK41_RS03460 a6bfb4ac122a4a4871a0bdcc3e9a404a 909 Pfam PF01751 Toprim domain 7 129 5.0E-27 T 28-03-2018 IPR006171 TOPRIM domain CFK41_RS03460 a6bfb4ac122a4a4871a0bdcc3e9a404a 909 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 92 105 4.2E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CFK41_RS03460 a6bfb4ac122a4a4871a0bdcc3e9a404a 909 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 515 529 4.2E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CFK41_RS03460 a6bfb4ac122a4a4871a0bdcc3e9a404a 909 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 178 196 4.2E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CFK41_RS03460 a6bfb4ac122a4a4871a0bdcc3e9a404a 909 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 402 418 4.2E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CFK41_RS03460 a6bfb4ac122a4a4871a0bdcc3e9a404a 909 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 323 332 4.2E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CFK41_RS03460 a6bfb4ac122a4a4871a0bdcc3e9a404a 909 Pfam PF01131 DNA topoisomerase 144 589 1.7E-117 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CFK41_RS03460 a6bfb4ac122a4a4871a0bdcc3e9a404a 909 Gene3D G3DSA:2.70.20.10 356 491 7.7E-42 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CFK41_RS03460 a6bfb4ac122a4a4871a0bdcc3e9a404a 909 Gene3D G3DSA:1.10.460.10 151 355 4.4E-43 T 28-03-2018 CFK41_RS03460 a6bfb4ac122a4a4871a0bdcc3e9a404a 909 Gene3D G3DSA:1.10.460.10 492 595 6.1E-19 T 28-03-2018 CFK41_RS03460 a6bfb4ac122a4a4871a0bdcc3e9a404a 909 SMART SM00436 120 208 2.4E-48 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CFK41_RS03460 a6bfb4ac122a4a4871a0bdcc3e9a404a 909 SMART SM00493 5 118 6.2E-30 T 28-03-2018 IPR006171 TOPRIM domain CFK41_RS03460 a6bfb4ac122a4a4871a0bdcc3e9a404a 909 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 7 642 2.5E-231 T 28-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 CFK41_RS03460 a6bfb4ac122a4a4871a0bdcc3e9a404a 909 Pfam PF13368 Topoisomerase C-terminal repeat 766 818 3.7E-15 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat CFK41_RS03460 a6bfb4ac122a4a4871a0bdcc3e9a404a 909 Pfam PF13368 Topoisomerase C-terminal repeat 830 882 9.2E-18 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat CFK41_RS03460 a6bfb4ac122a4a4871a0bdcc3e9a404a 909 Pfam PF13368 Topoisomerase C-terminal repeat 692 761 6.1E-13 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat CFK41_RS03460 a6bfb4ac122a4a4871a0bdcc3e9a404a 909 Pfam PF13368 Topoisomerase C-terminal repeat 625 684 1.5E-6 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat CFK41_RS03460 a6bfb4ac122a4a4871a0bdcc3e9a404a 909 SUPERFAMILY SSF56712 5 593 1.96E-176 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CFK41_RS03460 a6bfb4ac122a4a4871a0bdcc3e9a404a 909 Hamap MF_00952 DNA topoisomerase 1 [topA]. 5 776 50.66 T 28-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 CFK41_RS12455 aa8b00bc74bc344e9029d1e7692c5703 432 SUPERFAMILY SSF52540 1 426 1.17E-170 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS12455 aa8b00bc74bc344e9029d1e7692c5703 432 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 425 6.6E-162 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CFK41_RS12455 aa8b00bc74bc344e9029d1e7692c5703 432 Gene3D G3DSA:3.90.170.10 265 428 1.0E-65 T 28-03-2018 CFK41_RS12455 aa8b00bc74bc344e9029d1e7692c5703 432 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 28-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CFK41_RS12455 aa8b00bc74bc344e9029d1e7692c5703 432 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 432 200.058 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CFK41_RS12455 aa8b00bc74bc344e9029d1e7692c5703 432 Gene3D G3DSA:3.40.440.10 1 149 4.0E-49 T 28-03-2018 CFK41_RS12455 aa8b00bc74bc344e9029d1e7692c5703 432 Gene3D G3DSA:3.40.440.10 150 264 7.8E-30 T 28-03-2018 CFK41_RS12455 aa8b00bc74bc344e9029d1e7692c5703 432 SMART SM00788 3 422 2.8E-279 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CFK41_RS12455 aa8b00bc74bc344e9029d1e7692c5703 432 Pfam PF00709 Adenylosuccinate synthetase 4 421 2.3E-175 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CFK41_RS12455 aa8b00bc74bc344e9029d1e7692c5703 432 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 28-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CFK41_RS14840 65f1039f75794b4319cdc06501a6f9dc 287 Gene3D G3DSA:3.20.20.100 1 287 2.1E-70 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS14840 65f1039f75794b4319cdc06501a6f9dc 287 SUPERFAMILY SSF51430 6 286 1.3E-69 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS14840 65f1039f75794b4319cdc06501a6f9dc 287 PRINTS PR00069 Aldo-keto reductase signature 47 71 2.2E-8 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS14840 65f1039f75794b4319cdc06501a6f9dc 287 PRINTS PR00069 Aldo-keto reductase signature 112 130 2.2E-8 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS14840 65f1039f75794b4319cdc06501a6f9dc 287 PRINTS PR00069 Aldo-keto reductase signature 143 160 2.2E-8 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS14840 65f1039f75794b4319cdc06501a6f9dc 287 PRINTS PR00069 Aldo-keto reductase signature 220 244 2.2E-8 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS14840 65f1039f75794b4319cdc06501a6f9dc 287 Pfam PF00248 Aldo/keto reductase family 14 284 2.0E-57 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS03930 f8526ae96ae904736e8f2291ba217188 127 Gene3D G3DSA:3.40.50.620 1 127 1.6E-18 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS03930 f8526ae96ae904736e8f2291ba217188 127 Pfam PF00582 Universal stress protein family 3 127 1.7E-12 T 28-03-2018 IPR006016 UspA GO:0006950 CFK41_RS03930 f8526ae96ae904736e8f2291ba217188 127 SUPERFAMILY SSF52402 3 127 3.3E-16 T 28-03-2018 CFK41_RS10765 cb43f39ce4a8dfd8d57bcadf628809b5 281 Pfam PF00248 Aldo/keto reductase family 206 265 2.4E-6 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS10765 cb43f39ce4a8dfd8d57bcadf628809b5 281 Pfam PF00248 Aldo/keto reductase family 23 197 2.6E-26 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS10765 cb43f39ce4a8dfd8d57bcadf628809b5 281 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 234 249 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CFK41_RS10765 cb43f39ce4a8dfd8d57bcadf628809b5 281 PRINTS PR00069 Aldo-keto reductase signature 129 146 2.1E-33 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS10765 cb43f39ce4a8dfd8d57bcadf628809b5 281 PRINTS PR00069 Aldo-keto reductase signature 41 65 2.1E-33 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS10765 cb43f39ce4a8dfd8d57bcadf628809b5 281 PRINTS PR00069 Aldo-keto reductase signature 201 225 2.1E-33 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS10765 cb43f39ce4a8dfd8d57bcadf628809b5 281 PRINTS PR00069 Aldo-keto reductase signature 97 115 2.1E-33 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS10765 cb43f39ce4a8dfd8d57bcadf628809b5 281 PRINTS PR00069 Aldo-keto reductase signature 163 192 2.1E-33 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS10765 cb43f39ce4a8dfd8d57bcadf628809b5 281 Gene3D G3DSA:3.20.20.100 3 281 1.2E-71 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS10765 cb43f39ce4a8dfd8d57bcadf628809b5 281 SUPERFAMILY SSF51430 10 271 9.17E-70 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS10765 cb43f39ce4a8dfd8d57bcadf628809b5 281 PIRSF PIRSF000097 7 121 4.7E-22 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS10765 cb43f39ce4a8dfd8d57bcadf628809b5 281 PIRSF PIRSF000097 118 275 2.0E-30 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS10765 cb43f39ce4a8dfd8d57bcadf628809b5 281 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 45 62 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CFK41_RS10765 cb43f39ce4a8dfd8d57bcadf628809b5 281 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 129 146 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CFK41_RS10835 1ee1086e07fde4f41721263436fe6376 433 Pfam PF13439 Glycosyltransferase Family 4 49 218 2.7E-31 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CFK41_RS10835 1ee1086e07fde4f41721263436fe6376 433 Pfam PF00534 Glycosyl transferases group 1 233 393 8.8E-34 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CFK41_RS10835 1ee1086e07fde4f41721263436fe6376 433 SUPERFAMILY SSF53756 37 416 3.14E-82 T 28-03-2018 CFK41_RS10835 1ee1086e07fde4f41721263436fe6376 433 Gene3D G3DSA:3.40.50.2000 30 226 4.7E-22 T 28-03-2018 CFK41_RS10835 1ee1086e07fde4f41721263436fe6376 433 Gene3D G3DSA:3.40.50.2000 227 399 1.2E-44 T 28-03-2018 CFK41_RS04655 42aa4ec6ab9d0a0ad81b57e0da12f004 132 Gene3D G3DSA:3.30.1490.10 70 130 1.8E-20 T 28-03-2018 CFK41_RS04655 42aa4ec6ab9d0a0ad81b57e0da12f004 132 Pfam PF00410 Ribosomal protein S8 5 132 7.0E-49 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04655 42aa4ec6ab9d0a0ad81b57e0da12f004 132 Gene3D G3DSA:3.30.1370.30 1 67 2.1E-23 T 28-03-2018 CFK41_RS04655 42aa4ec6ab9d0a0ad81b57e0da12f004 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 30.959 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04655 42aa4ec6ab9d0a0ad81b57e0da12f004 132 SUPERFAMILY SSF56047 3 132 4.71E-44 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04655 42aa4ec6ab9d0a0ad81b57e0da12f004 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS00090 0d17844f21a7d972975127c097d82db3 220 SUPERFAMILY SSF53056 5 211 9.42E-48 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CFK41_RS00090 0d17844f21a7d972975127c097d82db3 220 Gene3D G3DSA:3.40.1050.10 1 213 1.0E-50 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CFK41_RS00090 0d17844f21a7d972975127c097d82db3 220 Pfam PF00484 Carbonic anhydrase 48 207 2.7E-38 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CFK41_RS00090 0d17844f21a7d972975127c097d82db3 220 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 53 60 - T 28-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CFK41_RS00090 0d17844f21a7d972975127c097d82db3 220 SMART SM00947 41 211 3.7E-44 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CFK41_RS00960 4b361096048458d4dcc192e0e9ee9155 371 SUPERFAMILY SSF53686 41 353 2.75E-62 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CFK41_RS00960 4b361096048458d4dcc192e0e9ee9155 371 Gene3D G3DSA:3.40.50.1100 48 159 1.9E-22 T 28-03-2018 CFK41_RS00960 4b361096048458d4dcc192e0e9ee9155 371 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 42 333 7.7E-42 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CFK41_RS00960 4b361096048458d4dcc192e0e9ee9155 371 Gene3D G3DSA:3.40.50.1100 160 348 8.9E-37 T 28-03-2018 CFK41_RS06535 4431afbd945857cfc51039478a701592 1313 Gene3D G3DSA:3.40.50.300 228 421 4.1E-47 T 28-03-2018 CFK41_RS06535 4431afbd945857cfc51039478a701592 1313 SMART SM00382 56 381 7.1E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS06535 4431afbd945857cfc51039478a701592 1313 Pfam PF00270 DEAD/DEAH box helicase 53 199 4.5E-6 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CFK41_RS06535 4431afbd945857cfc51039478a701592 1313 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 620 696 5.7E-19 T 28-03-2018 IPR011709 Domain of unknown function DUF1605 CFK41_RS06535 4431afbd945857cfc51039478a701592 1313 SMART SM00490 290 401 1.6E-17 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS06535 4431afbd945857cfc51039478a701592 1313 Pfam PF11898 Domain of unknown function (DUF3418) 710 1309 1.9E-191 T 28-03-2018 IPR024590 RNA helicase HrpA, C-terminal CFK41_RS06535 4431afbd945857cfc51039478a701592 1313 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 19 1308 0.0 T 28-03-2018 IPR010222 RNA helicase HrpA GO:0004004 CFK41_RS06535 4431afbd945857cfc51039478a701592 1313 Gene3D G3DSA:3.40.50.300 40 201 5.5E-30 T 28-03-2018 CFK41_RS06535 4431afbd945857cfc51039478a701592 1313 SUPERFAMILY SSF52540 38 591 1.28E-98 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS06535 4431afbd945857cfc51039478a701592 1313 SMART SM00487 43 225 1.8E-25 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CFK41_RS06535 4431afbd945857cfc51039478a701592 1313 Pfam PF00271 Helicase conserved C-terminal domain 272 400 1.9E-12 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS06535 4431afbd945857cfc51039478a701592 1313 Pfam PF04408 Helicase associated domain (HA2) 463 554 2.2E-16 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 CFK41_RS06535 4431afbd945857cfc51039478a701592 1313 SMART SM00847 461 557 1.2E-34 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 CFK41_RS07855 804a51925edbc9f3ccde23155a367e10 395 SUPERFAMILY SSF69118 198 385 5.09E-32 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CFK41_RS07855 804a51925edbc9f3ccde23155a367e10 395 Gene3D G3DSA:1.20.1290.10 213 394 5.2E-22 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CFK41_RS07855 804a51925edbc9f3ccde23155a367e10 395 Gene3D G3DSA:1.20.1290.10 7 164 1.8E-6 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CFK41_RS07855 804a51925edbc9f3ccde23155a367e10 395 Pfam PF02627 Carboxymuconolactone decarboxylase family 240 309 9.9E-13 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CFK41_RS07855 804a51925edbc9f3ccde23155a367e10 395 SUPERFAMILY SSF69118 25 155 1.96E-12 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CFK41_RS07855 804a51925edbc9f3ccde23155a367e10 395 TIGRFAM TIGR01926 peroxid_rel: uncharacterized peroxidase-related enzyme 204 388 3.6E-38 T 28-03-2018 IPR010195 Uncharacterised peroxidase-related CFK41_RS07855 804a51925edbc9f3ccde23155a367e10 395 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 259 305 2.8E-10 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CFK41_RS10275 010df4721f827e0c35894bbd29d77563 279 PIRSF PIRSF005917 1 279 6.8E-88 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CFK41_RS10275 010df4721f827e0c35894bbd29d77563 279 Gene3D G3DSA:3.30.950.10 117 230 2.4E-40 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CFK41_RS10275 010df4721f827e0c35894bbd29d77563 279 Gene3D G3DSA:3.40.1010.10 4 116 2.3E-33 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CFK41_RS10275 010df4721f827e0c35894bbd29d77563 279 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 7 208 9.6E-30 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CFK41_RS10275 010df4721f827e0c35894bbd29d77563 279 SUPERFAMILY SSF53790 5 225 1.3E-72 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CFK41_RS10275 010df4721f827e0c35894bbd29d77563 279 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 6 277 8.7E-61 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CFK41_RS10275 010df4721f827e0c35894bbd29d77563 279 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 6 227 33.152 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CFK41_RS02295 449cebd2c44df860317db0c5f71e2d5c 810 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 751 765 1.5E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS02295 449cebd2c44df860317db0c5f71e2d5c 810 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 765 781 1.5E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS02295 449cebd2c44df860317db0c5f71e2d5c 810 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 781 793 1.5E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS02295 449cebd2c44df860317db0c5f71e2d5c 810 SMART SM00421 748 805 1.9E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS02295 449cebd2c44df860317db0c5f71e2d5c 810 Gene3D G3DSA:1.10.10.10 755 810 9.5E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS02295 449cebd2c44df860317db0c5f71e2d5c 810 SUPERFAMILY SSF46894 743 810 2.93E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CFK41_RS02295 449cebd2c44df860317db0c5f71e2d5c 810 Gene3D G3DSA:1.25.40.10 140 754 7.6E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CFK41_RS02295 449cebd2c44df860317db0c5f71e2d5c 810 Pfam PF00196 Bacterial regulatory proteins, luxR family 751 803 1.1E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS11130 cba077d708e2a48d4ea689653afc1e96 589 SUPERFAMILY SSF52540 339 587 9.73E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11130 cba077d708e2a48d4ea689653afc1e96 589 Gene3D G3DSA:1.20.1560.10 23 325 8.3E-5 T 28-03-2018 CFK41_RS11130 cba077d708e2a48d4ea689653afc1e96 589 Gene3D G3DSA:3.40.50.300 344 589 4.1E-59 T 28-03-2018 CFK41_RS11130 cba077d708e2a48d4ea689653afc1e96 589 SUPERFAMILY SSF90123 31 304 1.44E-10 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS11130 cba077d708e2a48d4ea689653afc1e96 589 SMART SM00382 373 569 6.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS11130 cba077d708e2a48d4ea689653afc1e96 589 Pfam PF00005 ABC transporter 365 517 4.0E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS14250 71f8f04406192c4ba1c6eb578f848298 288 SUPERFAMILY SSF51735 1 161 3.94E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS14250 71f8f04406192c4ba1c6eb578f848298 288 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 163 283 3.6E-33 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CFK41_RS14250 71f8f04406192c4ba1c6eb578f848298 288 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 160 3.0E-44 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CFK41_RS14250 71f8f04406192c4ba1c6eb578f848298 288 Gene3D G3DSA:3.40.50.720 1 160 2.3E-31 T 28-03-2018 CFK41_RS14250 71f8f04406192c4ba1c6eb578f848298 288 SUPERFAMILY SSF48179 161 285 9.18E-36 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CFK41_RS14250 71f8f04406192c4ba1c6eb578f848298 288 PIRSF PIRSF000103 1 288 1.1E-77 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CFK41_RS14250 71f8f04406192c4ba1c6eb578f848298 288 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 5 18 - T 28-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 CFK41_RS14250 71f8f04406192c4ba1c6eb578f848298 288 Gene3D G3DSA:1.10.1040.10 161 288 3.1E-32 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CFK41_RS17100 38bc8185b9262cc250fe54d02d5c6308 294 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 168 288 2.5E-29 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CFK41_RS17100 38bc8185b9262cc250fe54d02d5c6308 294 Gene3D G3DSA:1.10.1040.10 167 293 2.3E-31 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CFK41_RS17100 38bc8185b9262cc250fe54d02d5c6308 294 SUPERFAMILY SSF48179 167 291 2.38E-33 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CFK41_RS17100 38bc8185b9262cc250fe54d02d5c6308 294 PIRSF PIRSF000103 1 293 1.7E-62 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CFK41_RS17100 38bc8185b9262cc250fe54d02d5c6308 294 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 7 161 7.7E-36 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CFK41_RS17100 38bc8185b9262cc250fe54d02d5c6308 294 SUPERFAMILY SSF51735 6 165 3.68E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS17100 38bc8185b9262cc250fe54d02d5c6308 294 Gene3D G3DSA:3.40.50.720 5 166 1.0E-25 T 28-03-2018 CFK41_RS13150 688e6bc9c4b263efe9fcf492ab122cdc 225 SUPERFAMILY SSF51219 23 219 2.12E-47 T 28-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain CFK41_RS13150 688e6bc9c4b263efe9fcf492ab122cdc 225 Gene3D G3DSA:3.60.160.10 8 224 8.4E-47 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 CFK41_RS13150 688e6bc9c4b263efe9fcf492ab122cdc 225 Pfam PF01987 Mitochondrial biogenesis AIM24 24 215 2.3E-34 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 CFK41_RS10760 205dcd9ea2d8d4ee8579e3d0849bbde7 410 PIRSF PIRSF006356 3 410 1.0E-120 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CFK41_RS10760 205dcd9ea2d8d4ee8579e3d0849bbde7 410 SUPERFAMILY SSF55909 8 410 1.96E-104 T 28-03-2018 CFK41_RS10760 205dcd9ea2d8d4ee8579e3d0849bbde7 410 PRINTS PR01466 Bacterial arginine deiminase signature 185 200 2.2E-46 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CFK41_RS10760 205dcd9ea2d8d4ee8579e3d0849bbde7 410 PRINTS PR01466 Bacterial arginine deiminase signature 157 175 2.2E-46 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CFK41_RS10760 205dcd9ea2d8d4ee8579e3d0849bbde7 410 PRINTS PR01466 Bacterial arginine deiminase signature 391 409 2.2E-46 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CFK41_RS10760 205dcd9ea2d8d4ee8579e3d0849bbde7 410 PRINTS PR01466 Bacterial arginine deiminase signature 348 365 2.2E-46 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CFK41_RS10760 205dcd9ea2d8d4ee8579e3d0849bbde7 410 PRINTS PR01466 Bacterial arginine deiminase signature 7 27 2.2E-46 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CFK41_RS10760 205dcd9ea2d8d4ee8579e3d0849bbde7 410 PRINTS PR01466 Bacterial arginine deiminase signature 368 382 2.2E-46 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CFK41_RS10760 205dcd9ea2d8d4ee8579e3d0849bbde7 410 Gene3D G3DSA:3.75.10.10 8 410 9.8E-85 T 28-03-2018 CFK41_RS10760 205dcd9ea2d8d4ee8579e3d0849bbde7 410 Pfam PF02274 Amidinotransferase 23 409 3.5E-81 T 28-03-2018 CFK41_RS10855 4ef2d7517cfb7c496194ae8f60837797 334 Gene3D G3DSA:2.60.260.20 153 221 9.0E-19 T 28-03-2018 CFK41_RS10855 4ef2d7517cfb7c496194ae8f60837797 334 Pfam PF00226 DnaJ domain 10 72 2.3E-26 T 28-03-2018 IPR001623 DnaJ domain CFK41_RS10855 4ef2d7517cfb7c496194ae8f60837797 334 SMART SM00271 9 67 1.3E-27 T 28-03-2018 IPR001623 DnaJ domain CFK41_RS10855 4ef2d7517cfb7c496194ae8f60837797 334 SUPERFAMILY SSF46565 9 110 3.14E-30 T 28-03-2018 IPR001623 DnaJ domain CFK41_RS10855 4ef2d7517cfb7c496194ae8f60837797 334 Gene3D G3DSA:2.60.260.20 223 332 2.8E-23 T 28-03-2018 CFK41_RS10855 4ef2d7517cfb7c496194ae8f60837797 334 Pfam PF01556 DnaJ C terminal domain 161 301 1.1E-31 T 28-03-2018 IPR002939 Chaperone DnaJ, C-terminal CFK41_RS10855 4ef2d7517cfb7c496194ae8f60837797 334 Gene3D G3DSA:1.10.287.110 6 115 1.7E-31 T 28-03-2018 IPR001623 DnaJ domain CFK41_RS10855 4ef2d7517cfb7c496194ae8f60837797 334 PRINTS PR00625 DnaJ domain signature 67 86 1.4E-20 T 28-03-2018 IPR001623 DnaJ domain CFK41_RS10855 4ef2d7517cfb7c496194ae8f60837797 334 PRINTS PR00625 DnaJ domain signature 12 30 1.4E-20 T 28-03-2018 IPR001623 DnaJ domain CFK41_RS10855 4ef2d7517cfb7c496194ae8f60837797 334 PRINTS PR00625 DnaJ domain signature 30 45 1.4E-20 T 28-03-2018 IPR001623 DnaJ domain CFK41_RS10855 4ef2d7517cfb7c496194ae8f60837797 334 PRINTS PR00625 DnaJ domain signature 47 67 1.4E-20 T 28-03-2018 IPR001623 DnaJ domain CFK41_RS10855 4ef2d7517cfb7c496194ae8f60837797 334 ProSitePatterns PS00636 Nt-dnaJ domain signature. 52 71 - T 28-03-2018 IPR018253 DnaJ domain, conserved site CFK41_RS10855 4ef2d7517cfb7c496194ae8f60837797 334 SUPERFAMILY SSF49493 152 235 6.28E-19 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CFK41_RS10855 4ef2d7517cfb7c496194ae8f60837797 334 SUPERFAMILY SSF49493 229 309 7.46E-19 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CFK41_RS08110 2e66954080f89642035010ce98039ca3 626 SUPERFAMILY SSF52540 20 243 4.82E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS08110 2e66954080f89642035010ce98039ca3 626 Gene3D G3DSA:3.30.70.240 413 568 9.0E-27 T 28-03-2018 CFK41_RS08110 2e66954080f89642035010ce98039ca3 626 Gene3D G3DSA:2.40.30.10 194 298 3.7E-21 T 28-03-2018 CFK41_RS08110 2e66954080f89642035010ce98039ca3 626 Gene3D G3DSA:3.40.50.300 18 193 7.9E-36 T 28-03-2018 CFK41_RS08110 2e66954080f89642035010ce98039ca3 626 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 63 78 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CFK41_RS08110 2e66954080f89642035010ce98039ca3 626 SMART SM00838 417 501 0.0016 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CFK41_RS08110 2e66954080f89642035010ce98039ca3 626 Hamap MF_00071 Elongation factor 4 [lepA]. 1 617 281.475 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 CFK41_RS08110 2e66954080f89642035010ce98039ca3 626 Pfam PF06421 GTP-binding protein LepA C-terminus 508 612 4.9E-49 T 28-03-2018 IPR013842 GTP-binding protein LepA, C-terminal CFK41_RS08110 2e66954080f89642035010ce98039ca3 626 TIGRFAM TIGR01393 lepA: elongation factor 4 24 614 4.2E-289 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 CFK41_RS08110 2e66954080f89642035010ce98039ca3 626 Pfam PF00009 Elongation factor Tu GTP binding domain 24 202 2.1E-52 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS08110 2e66954080f89642035010ce98039ca3 626 Pfam PF00679 Elongation factor G C-terminus 418 504 6.0E-21 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CFK41_RS08110 2e66954080f89642035010ce98039ca3 626 SUPERFAMILY SSF54980 311 390 4.32E-18 T 28-03-2018 IPR035647 EF-G domain III/V-like CFK41_RS08110 2e66954080f89642035010ce98039ca3 626 PRINTS PR00315 GTP-binding elongation factor signature 70 78 8.1E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS08110 2e66954080f89642035010ce98039ca3 626 PRINTS PR00315 GTP-binding elongation factor signature 146 155 8.1E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS08110 2e66954080f89642035010ce98039ca3 626 PRINTS PR00315 GTP-binding elongation factor signature 110 121 8.1E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS08110 2e66954080f89642035010ce98039ca3 626 PRINTS PR00315 GTP-binding elongation factor signature 94 104 8.1E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS08110 2e66954080f89642035010ce98039ca3 626 PRINTS PR00315 GTP-binding elongation factor signature 27 40 8.1E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS08110 2e66954080f89642035010ce98039ca3 626 SUPERFAMILY SSF54980 418 513 6.23E-23 T 28-03-2018 IPR035647 EF-G domain III/V-like CFK41_RS08110 2e66954080f89642035010ce98039ca3 626 Gene3D G3DSA:3.30.70.870 306 387 1.2E-25 T 28-03-2018 CFK41_RS08110 2e66954080f89642035010ce98039ca3 626 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 26 171 2.6E-19 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CFK41_RS12520 14a1f23a7c65e7264ff87336bdb5b486 133 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 19 113 2.1E-21 T 28-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane CFK41_RS12520 14a1f23a7c65e7264ff87336bdb5b486 133 Pfam PF12823 Domain of unknown function (DUF3817) 17 114 4.6E-25 T 28-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane CFK41_RS02325 1853af46236cf7d40e01e5d736fe6005 153 SMART SM00530 11 66 8.0E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CFK41_RS02325 1853af46236cf7d40e01e5d736fe6005 153 SUPERFAMILY SSF81301 80 140 3.78E-14 T 28-03-2018 CFK41_RS02325 1853af46236cf7d40e01e5d736fe6005 153 Pfam PF13560 Helix-turn-helix domain 10 64 1.1E-10 T 28-03-2018 CFK41_RS02325 1853af46236cf7d40e01e5d736fe6005 153 Gene3D G3DSA:3.30.460.10 65 152 1.2E-13 T 28-03-2018 CFK41_RS02325 1853af46236cf7d40e01e5d736fe6005 153 Pfam PF01909 Nucleotidyltransferase domain 76 140 1.6E-7 T 28-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 CFK41_RS02325 1853af46236cf7d40e01e5d736fe6005 153 SUPERFAMILY SSF47413 11 67 8.31E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS02325 1853af46236cf7d40e01e5d736fe6005 153 Gene3D G3DSA:1.10.260.40 2 64 1.1E-13 T 28-03-2018 CFK41_RS16390 948d80dc81269e0fac68bc2a47b0fba3 346 Gene3D G3DSA:1.10.260.40 11 55 3.8E-17 T 28-03-2018 CFK41_RS16390 948d80dc81269e0fac68bc2a47b0fba3 346 ProSitePatterns PS00356 LacI-type HTH domain signature. 13 31 - T 28-03-2018 CFK41_RS16390 948d80dc81269e0fac68bc2a47b0fba3 346 SUPERFAMILY SSF47413 10 58 3.15E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS16390 948d80dc81269e0fac68bc2a47b0fba3 346 Gene3D G3DSA:3.40.50.2300 56 183 4.8E-23 T 28-03-2018 CFK41_RS16390 948d80dc81269e0fac68bc2a47b0fba3 346 SMART SM00354 10 76 2.7E-9 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS16390 948d80dc81269e0fac68bc2a47b0fba3 346 Pfam PF13377 Periplasmic binding protein-like domain 177 338 2.2E-36 T 28-03-2018 CFK41_RS16390 948d80dc81269e0fac68bc2a47b0fba3 346 SUPERFAMILY SSF53822 70 341 7.07E-67 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS16390 948d80dc81269e0fac68bc2a47b0fba3 346 Pfam PF00356 Bacterial regulatory proteins, lacI family 12 56 1.6E-16 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS16390 948d80dc81269e0fac68bc2a47b0fba3 346 Gene3D G3DSA:3.40.50.2300 184 314 2.9E-46 T 28-03-2018 CFK41_RS10195 5bbc7f59ab5470196606561a206a99ff 427 Pfam PF03952 Enolase, N-terminal domain 5 135 1.1E-57 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS10195 5bbc7f59ab5470196606561a206a99ff 427 Hamap MF_00318 Enolase [eno]. 3 410 45.323 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS10195 5bbc7f59ab5470196606561a206a99ff 427 Gene3D G3DSA:3.30.390.10 4 127 5.0E-51 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS10195 5bbc7f59ab5470196606561a206a99ff 427 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 5 424 1.9E-203 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS10195 5bbc7f59ab5470196606561a206a99ff 427 SMART SM01192 140 424 1.5E-224 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS10195 5bbc7f59ab5470196606561a206a99ff 427 SUPERFAMILY SSF54826 5 139 1.54E-53 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS10195 5bbc7f59ab5470196606561a206a99ff 427 PRINTS PR00148 Enolase signature 38 52 7.1E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS10195 5bbc7f59ab5470196606561a206a99ff 427 PRINTS PR00148 Enolase signature 310 321 7.1E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS10195 5bbc7f59ab5470196606561a206a99ff 427 PRINTS PR00148 Enolase signature 362 379 7.1E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS10195 5bbc7f59ab5470196606561a206a99ff 427 PRINTS PR00148 Enolase signature 162 175 7.1E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS10195 5bbc7f59ab5470196606561a206a99ff 427 PRINTS PR00148 Enolase signature 333 347 7.1E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS10195 5bbc7f59ab5470196606561a206a99ff 427 PRINTS PR00148 Enolase signature 108 124 7.1E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS10195 5bbc7f59ab5470196606561a206a99ff 427 Gene3D G3DSA:3.20.20.120 129 427 2.1E-108 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS10195 5bbc7f59ab5470196606561a206a99ff 427 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 421 1.9E-133 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS10195 5bbc7f59ab5470196606561a206a99ff 427 ProSitePatterns PS00164 Enolase signature. 333 346 - T 28-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS10195 5bbc7f59ab5470196606561a206a99ff 427 SMART SM01193 5 135 3.1E-88 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS10195 5bbc7f59ab5470196606561a206a99ff 427 SUPERFAMILY SSF51604 139 423 7.89E-131 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS10195 5bbc7f59ab5470196606561a206a99ff 427 PIRSF PIRSF001400 1 423 3.9E-189 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS13510 88f7ae78b44b37217e9369952e260ac9 170 Gene3D G3DSA:3.40.630.30 1 162 7.7E-18 T 28-03-2018 CFK41_RS13510 88f7ae78b44b37217e9369952e260ac9 170 SUPERFAMILY SSF55729 14 156 2.09E-16 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS13510 88f7ae78b44b37217e9369952e260ac9 170 Pfam PF00583 Acetyltransferase (GNAT) family 23 150 3.8E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS17485 0cec9476aaf970cb864c5224ad851b79 122 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 8 107 7.0E-8 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CFK41_RS17485 0cec9476aaf970cb864c5224ad851b79 122 Pfam PF00825 Ribonuclease P 5 110 1.8E-25 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CFK41_RS17485 0cec9476aaf970cb864c5224ad851b79 122 Gene3D G3DSA:3.30.230.10 3 119 2.8E-32 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CFK41_RS17485 0cec9476aaf970cb864c5224ad851b79 122 SUPERFAMILY SSF54211 5 111 7.33E-24 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CFK41_RS17485 0cec9476aaf970cb864c5224ad851b79 122 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 5 91 1.0E-15 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CFK41_RS17485 0cec9476aaf970cb864c5224ad851b79 122 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 2 113 15.604 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CFK41_RS03450 f14ea629fd92307f6be5c498400878da 349 Gene3D G3DSA:1.20.58.370 1 94 1.1E-6 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CFK41_RS03450 f14ea629fd92307f6be5c498400878da 349 SUPERFAMILY SSF161098 62 345 2.35E-45 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS03450 f14ea629fd92307f6be5c498400878da 349 Gene3D G3DSA:1.10.3720.10 111 345 7.2E-42 T 28-03-2018 CFK41_RS03450 f14ea629fd92307f6be5c498400878da 349 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 138 338 8.3E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS16880 10cbbb0cf0edeb8f6ff4ca15cfed5b89 277 Gene3D G3DSA:3.20.20.100 1 273 1.5E-87 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS16880 10cbbb0cf0edeb8f6ff4ca15cfed5b89 277 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 125 142 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CFK41_RS16880 10cbbb0cf0edeb8f6ff4ca15cfed5b89 277 SUPERFAMILY SSF51430 7 268 5.76E-88 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS16880 10cbbb0cf0edeb8f6ff4ca15cfed5b89 277 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 41 58 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CFK41_RS16880 10cbbb0cf0edeb8f6ff4ca15cfed5b89 277 Pfam PF00248 Aldo/keto reductase family 202 261 1.1E-6 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS16880 10cbbb0cf0edeb8f6ff4ca15cfed5b89 277 Pfam PF00248 Aldo/keto reductase family 18 194 5.1E-41 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS16880 10cbbb0cf0edeb8f6ff4ca15cfed5b89 277 PRINTS PR00069 Aldo-keto reductase signature 125 142 6.0E-41 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS16880 10cbbb0cf0edeb8f6ff4ca15cfed5b89 277 PRINTS PR00069 Aldo-keto reductase signature 159 188 6.0E-41 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS16880 10cbbb0cf0edeb8f6ff4ca15cfed5b89 277 PRINTS PR00069 Aldo-keto reductase signature 93 111 6.0E-41 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS16880 10cbbb0cf0edeb8f6ff4ca15cfed5b89 277 PRINTS PR00069 Aldo-keto reductase signature 37 61 6.0E-41 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS16880 10cbbb0cf0edeb8f6ff4ca15cfed5b89 277 PRINTS PR00069 Aldo-keto reductase signature 197 221 6.0E-41 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS16880 10cbbb0cf0edeb8f6ff4ca15cfed5b89 277 PIRSF PIRSF000097 1 273 2.7E-78 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS16880 10cbbb0cf0edeb8f6ff4ca15cfed5b89 277 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 230 245 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CFK41_RS12115 4bdd1fa3b28d726299e6bf4f6eacdc08 333 Gene3D G3DSA:3.30.70.20 208 328 4.9E-18 T 28-03-2018 CFK41_RS12115 4bdd1fa3b28d726299e6bf4f6eacdc08 333 SUPERFAMILY SSF54862 21 310 1.36E-60 T 28-03-2018 CFK41_RS12115 4bdd1fa3b28d726299e6bf4f6eacdc08 333 Pfam PF13247 4Fe-4S dicluster domain 133 243 4.0E-19 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CFK41_RS12115 4bdd1fa3b28d726299e6bf4f6eacdc08 333 Gene3D G3DSA:3.30.70.20 37 155 1.2E-35 T 28-03-2018 CFK41_RS12115 4bdd1fa3b28d726299e6bf4f6eacdc08 333 Gene3D G3DSA:3.30.70.20 12 36 0.0085 T 28-03-2018 CFK41_RS12115 4bdd1fa3b28d726299e6bf4f6eacdc08 333 Gene3D G3DSA:3.30.70.20 156 207 1.2E-16 T 28-03-2018 CFK41_RS12115 4bdd1fa3b28d726299e6bf4f6eacdc08 333 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 173 184 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CFK41_RS12115 4bdd1fa3b28d726299e6bf4f6eacdc08 333 PIRSF PIRSF036298 17 331 1.9E-55 T 28-03-2018 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 CFK41_RS12115 4bdd1fa3b28d726299e6bf4f6eacdc08 333 Pfam PF12800 4Fe-4S binding domain 32 43 0.018 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CFK41_RS10110 692746272613891f5f81d4f7903dda7d 582 Gene3D G3DSA:3.40.50.300 259 538 1.0E-19 T 28-03-2018 CFK41_RS10110 692746272613891f5f81d4f7903dda7d 582 SUPERFAMILY SSF52540 1 199 4.95E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS10110 692746272613891f5f81d4f7903dda7d 582 SUPERFAMILY SSF52540 348 525 4.95E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS10110 692746272613891f5f81d4f7903dda7d 582 SUPERFAMILY SSF52540 288 309 4.95E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS10110 692746272613891f5f81d4f7903dda7d 582 Gene3D G3DSA:3.40.50.300 1 240 4.3E-20 T 28-03-2018 CFK41_RS10110 692746272613891f5f81d4f7903dda7d 582 Pfam PF02463 RecF/RecN/SMC N terminal domain 9 522 6.0E-18 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CFK41_RS10110 692746272613891f5f81d4f7903dda7d 582 PIRSF PIRSF003128 1 570 3.6E-138 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CFK41_RS10110 692746272613891f5f81d4f7903dda7d 582 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 565 6.4E-131 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CFK41_RS01830 b9a6a6d77108915832a5bef4da358a32 387 SUPERFAMILY SSF55347 146 305 9.16E-29 T 28-03-2018 CFK41_RS01830 b9a6a6d77108915832a5bef4da358a32 387 Gene3D G3DSA:3.40.50.720 1 153 4.6E-29 T 28-03-2018 CFK41_RS01830 b9a6a6d77108915832a5bef4da358a32 387 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 50 137 1.2E-8 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS01830 b9a6a6d77108915832a5bef4da358a32 387 Gene3D G3DSA:3.30.360.10 154 385 1.3E-38 T 28-03-2018 CFK41_RS01830 b9a6a6d77108915832a5bef4da358a32 387 SUPERFAMILY SSF51735 49 173 1.82E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS09220 03ac1a4d0fcefca69f09c9a176ec1dbf 400 Gene3D G3DSA:3.40.50.1260 2 182 6.4E-65 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS09220 03ac1a4d0fcefca69f09c9a176ec1dbf 400 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 4 397 41.061 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS09220 03ac1a4d0fcefca69f09c9a176ec1dbf 400 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 28-03-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS09220 03ac1a4d0fcefca69f09c9a176ec1dbf 400 SUPERFAMILY SSF53748 4 397 2.36E-144 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS09220 03ac1a4d0fcefca69f09c9a176ec1dbf 400 PIRSF PIRSF000724 1 400 5.2E-136 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS09220 03ac1a4d0fcefca69f09c9a176ec1dbf 400 Pfam PF00162 Phosphoglycerate kinase 10 387 4.9E-149 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS09220 03ac1a4d0fcefca69f09c9a176ec1dbf 400 Gene3D G3DSA:3.40.50.1260 183 385 6.5E-83 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS09220 03ac1a4d0fcefca69f09c9a176ec1dbf 400 PRINTS PR00477 Phosphoglycerate kinase family signature 194 213 8.5E-82 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS09220 03ac1a4d0fcefca69f09c9a176ec1dbf 400 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 8.5E-82 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS09220 03ac1a4d0fcefca69f09c9a176ec1dbf 400 PRINTS PR00477 Phosphoglycerate kinase family signature 373 390 8.5E-82 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS09220 03ac1a4d0fcefca69f09c9a176ec1dbf 400 PRINTS PR00477 Phosphoglycerate kinase family signature 141 163 8.5E-82 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS09220 03ac1a4d0fcefca69f09c9a176ec1dbf 400 PRINTS PR00477 Phosphoglycerate kinase family signature 109 124 8.5E-82 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS09220 03ac1a4d0fcefca69f09c9a176ec1dbf 400 PRINTS PR00477 Phosphoglycerate kinase family signature 171 193 8.5E-82 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS09220 03ac1a4d0fcefca69f09c9a176ec1dbf 400 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 8.5E-82 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS09220 03ac1a4d0fcefca69f09c9a176ec1dbf 400 PRINTS PR00477 Phosphoglycerate kinase family signature 316 341 8.5E-82 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS09220 03ac1a4d0fcefca69f09c9a176ec1dbf 400 PRINTS PR00477 Phosphoglycerate kinase family signature 349 360 8.5E-82 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS11425 e3ce5054f209e00251ef1fb6dc39f12d 1190 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 9 1069 0.0 T 28-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CFK41_RS11425 e3ce5054f209e00251ef1fb6dc39f12d 1190 Pfam PF14579 Helix-hairpin-helix motif 835 924 6.2E-27 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CFK41_RS11425 e3ce5054f209e00251ef1fb6dc39f12d 1190 Gene3D G3DSA:1.10.150.280 822 920 7.1E-10 T 28-03-2018 CFK41_RS11425 e3ce5054f209e00251ef1fb6dc39f12d 1190 SMART SM00481 10 77 4.9E-30 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CFK41_RS11425 e3ce5054f209e00251ef1fb6dc39f12d 1190 Gene3D G3DSA:2.40.50.140 1008 1108 3.2E-14 T 28-03-2018 CFK41_RS11425 e3ce5054f209e00251ef1fb6dc39f12d 1190 Pfam PF02811 PHP domain 11 200 2.2E-46 T 28-03-2018 IPR004013 PHP domain GO:0003824 CFK41_RS11425 e3ce5054f209e00251ef1fb6dc39f12d 1190 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 322 762 1.8E-164 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CFK41_RS11425 e3ce5054f209e00251ef1fb6dc39f12d 1190 Pfam PF01336 OB-fold nucleic acid binding domain 1032 1108 1.2E-6 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CFK41_RS11425 e3ce5054f209e00251ef1fb6dc39f12d 1190 SUPERFAMILY SSF89550 9 95 4.71E-33 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CFK41_RS11425 e3ce5054f209e00251ef1fb6dc39f12d 1190 SUPERFAMILY SSF89550 126 290 4.71E-33 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CFK41_RS11425 e3ce5054f209e00251ef1fb6dc39f12d 1190 Gene3D G3DSA:3.20.20.140 6 276 5.2E-48 T 28-03-2018 CFK41_RS15440 a60f841e1e75eaad2e779521ef53785c 886 Pfam PF04408 Helicase associated domain (HA2) 418 478 4.2E-6 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 CFK41_RS15440 a60f841e1e75eaad2e779521ef53785c 886 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 29 881 1.5E-184 T 28-03-2018 IPR010225 ATP-dependent helicase HrpB GO:0008026 CFK41_RS15440 a60f841e1e75eaad2e779521ef53785c 886 SMART SM00487 25 208 1.0E-13 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CFK41_RS15440 a60f841e1e75eaad2e779521ef53785c 886 Pfam PF00271 Helicase conserved C-terminal domain 232 357 7.7E-13 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS15440 a60f841e1e75eaad2e779521ef53785c 886 SMART SM00847 417 516 1.9E-5 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 CFK41_RS15440 a60f841e1e75eaad2e779521ef53785c 886 Gene3D G3DSA:3.40.50.300 27 182 2.9E-20 T 28-03-2018 CFK41_RS15440 a60f841e1e75eaad2e779521ef53785c 886 Gene3D G3DSA:3.40.50.300 201 378 3.5E-29 T 28-03-2018 CFK41_RS15440 a60f841e1e75eaad2e779521ef53785c 886 SMART SM00490 254 357 2.8E-12 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS15440 a60f841e1e75eaad2e779521ef53785c 886 PIRSF PIRSF005496 23 884 2.8E-237 T 28-03-2018 CFK41_RS15440 a60f841e1e75eaad2e779521ef53785c 886 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 139 148 - T 28-03-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site CFK41_RS15440 a60f841e1e75eaad2e779521ef53785c 886 Pfam PF08482 ATP-dependent helicase C-terminal 736 870 8.0E-47 T 28-03-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal CFK41_RS15440 a60f841e1e75eaad2e779521ef53785c 886 SUPERFAMILY SSF52540 45 367 7.41E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS07360 82faa70af13d39a2be1ce9854a85e1f2 204 Gene3D G3DSA:3.20.19.10 1 169 1.2E-43 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CFK41_RS07360 82faa70af13d39a2be1ce9854a85e1f2 204 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 192 39.535 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CFK41_RS07360 82faa70af13d39a2be1ce9854a85e1f2 204 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 181 4.8E-59 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CFK41_RS07360 82faa70af13d39a2be1ce9854a85e1f2 204 Pfam PF00694 Aconitase C-terminal domain 1 112 8.4E-24 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS07360 82faa70af13d39a2be1ce9854a85e1f2 204 SUPERFAMILY SSF52016 1 191 9.61E-53 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CFK41_RS10075 2001c27cb80bb6b50e46b97cfd7ec757 230 Gene3D G3DSA:3.90.79.10 32 219 1.2E-37 T 28-03-2018 CFK41_RS10075 2001c27cb80bb6b50e46b97cfd7ec757 230 Pfam PF00293 NUDIX domain 69 182 4.6E-18 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CFK41_RS10075 2001c27cb80bb6b50e46b97cfd7ec757 230 SUPERFAMILY SSF55811 35 205 6.23E-42 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CFK41_RS15950 2fc5b9cad3a9b7502caa2619b09d2188 401 Pfam PF12704 MacB-like periplasmic core domain 23 240 1.6E-15 T 28-03-2018 IPR025857 MacB-like periplasmic core domain CFK41_RS15950 2fc5b9cad3a9b7502caa2619b09d2188 401 Pfam PF02687 FtsX-like permease family 301 393 1.6E-9 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CFK41_RS12245 5a464d93ed3378dfba2953e34165457a 141 Gene3D G3DSA:2.102.10.10 28 139 3.6E-22 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CFK41_RS12245 5a464d93ed3378dfba2953e34165457a 141 SUPERFAMILY SSF50022 30 137 5.63E-28 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CFK41_RS12245 5a464d93ed3378dfba2953e34165457a 141 PRINTS PR00162 Rieske 2Fe-2S subunit signature 100 112 9.0E-8 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CFK41_RS12245 5a464d93ed3378dfba2953e34165457a 141 PRINTS PR00162 Rieske 2Fe-2S subunit signature 81 92 9.0E-8 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CFK41_RS12245 5a464d93ed3378dfba2953e34165457a 141 PRINTS PR00162 Rieske 2Fe-2S subunit signature 113 125 9.0E-8 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CFK41_RS12245 5a464d93ed3378dfba2953e34165457a 141 Pfam PF00355 Rieske [2Fe-2S] domain 49 128 6.7E-16 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CFK41_RS11640 3bec5f87541e6b523cc3e77c1df7267f 74 Pfam PF11248 Protein of unknown function (DUF3046) 1 61 2.9E-23 T 28-03-2018 IPR021408 Protein of unknown function DUF3046 CFK41_RS00865 1580abbd6e182d427ecb398e2e145d8f 166 PIRSF PIRSF000303 1 166 3.7E-62 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CFK41_RS00865 1580abbd6e182d427ecb398e2e145d8f 166 SUPERFAMILY SSF52833 6 162 2.87E-58 T 28-03-2018 IPR012336 Thioredoxin-like fold CFK41_RS00865 1580abbd6e182d427ecb398e2e145d8f 166 Gene3D G3DSA:3.40.30.10 5 164 7.5E-46 T 28-03-2018 CFK41_RS00865 1580abbd6e182d427ecb398e2e145d8f 166 PRINTS PR01011 Glutathione peroxidase family signature 25 42 1.2E-16 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CFK41_RS00865 1580abbd6e182d427ecb398e2e145d8f 166 PRINTS PR01011 Glutathione peroxidase family signature 126 135 1.2E-16 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CFK41_RS00865 1580abbd6e182d427ecb398e2e145d8f 166 PRINTS PR01011 Glutathione peroxidase family signature 60 76 1.2E-16 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CFK41_RS00865 1580abbd6e182d427ecb398e2e145d8f 166 ProSitePatterns PS00460 Glutathione peroxidases active site. 27 42 - T 28-03-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 CFK41_RS00865 1580abbd6e182d427ecb398e2e145d8f 166 Pfam PF00255 Glutathione peroxidase 9 113 7.4E-40 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CFK41_RS03540 574deada8b44174f91770296c01152a1 341 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 8 339 1.0E-69 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CFK41_RS03540 574deada8b44174f91770296c01152a1 341 Gene3D G3DSA:3.20.20.70 1 341 6.0E-98 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS03540 574deada8b44174f91770296c01152a1 341 PIRSF PIRSF001359 4 340 2.0E-59 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CFK41_RS03540 574deada8b44174f91770296c01152a1 341 Pfam PF01116 Fructose-bisphosphate aldolase class-II 8 338 3.7E-77 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CFK41_RS03540 574deada8b44174f91770296c01152a1 341 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 86 97 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CFK41_RS03540 574deada8b44174f91770296c01152a1 341 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 159 170 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CFK41_RS03540 574deada8b44174f91770296c01152a1 341 SUPERFAMILY SSF51569 3 339 5.27E-96 T 28-03-2018 CFK41_RS03540 574deada8b44174f91770296c01152a1 341 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 2 338 4.3E-126 T 28-03-2018 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 CFK41_RS01580 95e7e0d267733d2cca2b6d5df1f8bb67 340 SMART SM00354 7 77 2.3E-28 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS01580 95e7e0d267733d2cca2b6d5df1f8bb67 340 Pfam PF13377 Periplasmic binding protein-like domain 175 334 3.4E-34 T 28-03-2018 CFK41_RS01580 95e7e0d267733d2cca2b6d5df1f8bb67 340 Gene3D G3DSA:3.40.50.2300 61 181 7.9E-26 T 28-03-2018 CFK41_RS01580 95e7e0d267733d2cca2b6d5df1f8bb67 340 Gene3D G3DSA:1.10.260.40 23 60 1.8E-21 T 28-03-2018 CFK41_RS01580 95e7e0d267733d2cca2b6d5df1f8bb67 340 SUPERFAMILY SSF53822 67 336 3.08E-57 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS01580 95e7e0d267733d2cca2b6d5df1f8bb67 340 Gene3D G3DSA:1.10.10.10 1 22 5.5E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS01580 95e7e0d267733d2cca2b6d5df1f8bb67 340 SUPERFAMILY SSF47413 7 65 1.31E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS01580 95e7e0d267733d2cca2b6d5df1f8bb67 340 Gene3D G3DSA:3.40.50.2300 182 316 4.0E-42 T 28-03-2018 CFK41_RS01580 95e7e0d267733d2cca2b6d5df1f8bb67 340 ProSitePatterns PS00356 LacI-type HTH domain signature. 10 28 - T 28-03-2018 CFK41_RS01580 95e7e0d267733d2cca2b6d5df1f8bb67 340 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 54 4.4E-18 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS09845 f222289b2e9767440b2adfca7b594193 244 Pfam PF00510 Cytochrome c oxidase subunit III 119 221 3.0E-18 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS09845 f222289b2e9767440b2adfca7b594193 244 SUPERFAMILY SSF81452 21 222 6.93E-46 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS09845 f222289b2e9767440b2adfca7b594193 244 Gene3D G3DSA:1.20.120.80 20 225 2.9E-53 T 28-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS01550 240906bad65958745d68edd1b92235ad 315 Gene3D G3DSA:3.40.50.20 5 101 9.2E-13 T 28-03-2018 CFK41_RS01550 240906bad65958745d68edd1b92235ad 315 SUPERFAMILY SSF56059 92 282 4.28E-13 T 28-03-2018 CFK41_RS01550 240906bad65958745d68edd1b92235ad 315 Gene3D G3DSA:3.30.470.20 102 306 5.5E-15 T 28-03-2018 CFK41_RS05770 a3929c55ddfe744415f166e9b7bd7588 306 Gene3D G3DSA:1.10.3720.10 6 268 3.7E-28 T 28-03-2018 CFK41_RS05770 a3929c55ddfe744415f166e9b7bd7588 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 266 1.3E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS05770 a3929c55ddfe744415f166e9b7bd7588 306 SUPERFAMILY SSF161098 71 259 3.27E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01515 240dcb25410858ae42852f928a2d1a0c 435 Pfam PF00480 ROK family 83 389 1.1E-47 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CFK41_RS01515 240dcb25410858ae42852f928a2d1a0c 435 Gene3D G3DSA:3.30.420.40 68 206 1.2E-27 T 28-03-2018 CFK41_RS01515 240dcb25410858ae42852f928a2d1a0c 435 SUPERFAMILY SSF46785 9 71 2.26E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS01515 240dcb25410858ae42852f928a2d1a0c 435 ProSitePatterns PS01125 ROK family signature. 216 243 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CFK41_RS01515 240dcb25410858ae42852f928a2d1a0c 435 Gene3D G3DSA:3.30.420.40 207 398 1.2E-46 T 28-03-2018 CFK41_RS01515 240dcb25410858ae42852f928a2d1a0c 435 Gene3D G3DSA:1.10.10.10 7 67 6.8E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS01515 240dcb25410858ae42852f928a2d1a0c 435 Pfam PF13412 Winged helix-turn-helix DNA-binding 10 57 2.3E-5 T 28-03-2018 CFK41_RS01515 240dcb25410858ae42852f928a2d1a0c 435 SUPERFAMILY SSF53067 80 391 2.16E-54 T 28-03-2018 CFK41_RS09290 4edfe1095a352a5cb30204a634abf0b4 701 SUPERFAMILY SSF46600 656 693 3.14E-10 T 28-03-2018 IPR001943 UVR domain GO:0005515 CFK41_RS09290 4edfe1095a352a5cb30204a634abf0b4 701 Pfam PF04851 Type III restriction enzyme, res subunit 21 140 1.1E-7 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CFK41_RS09290 4edfe1095a352a5cb30204a634abf0b4 701 Gene3D G3DSA:3.40.50.300 422 596 3.0E-32 T 28-03-2018 CFK41_RS09290 4edfe1095a352a5cb30204a634abf0b4 701 Gene3D G3DSA:4.10.860.10 623 698 2.9E-13 T 28-03-2018 IPR001943 UVR domain GO:0005515 CFK41_RS09290 4edfe1095a352a5cb30204a634abf0b4 701 Hamap MF_00204 UvrABC system protein B [uvrB]. 12 693 42.224 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CFK41_RS09290 4edfe1095a352a5cb30204a634abf0b4 701 SMART SM00490 467 553 1.0E-18 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS09290 4edfe1095a352a5cb30204a634abf0b4 701 Pfam PF12344 Ultra-violet resistance protein B 559 600 1.8E-21 T 28-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain CFK41_RS09290 4edfe1095a352a5cb30204a634abf0b4 701 Pfam PF02151 UvrB/uvrC motif 660 693 1.1E-9 T 28-03-2018 IPR001943 UVR domain GO:0005515 CFK41_RS09290 4edfe1095a352a5cb30204a634abf0b4 701 SUPERFAMILY SSF52540 477 599 2.7E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS09290 4edfe1095a352a5cb30204a634abf0b4 701 SUPERFAMILY SSF52540 41 89 2.7E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS09290 4edfe1095a352a5cb30204a634abf0b4 701 SUPERFAMILY SSF52540 13 422 5.89E-131 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS09290 4edfe1095a352a5cb30204a634abf0b4 701 Gene3D G3DSA:3.40.50.300 20 421 5.0E-32 T 28-03-2018 CFK41_RS09290 4edfe1095a352a5cb30204a634abf0b4 701 Pfam PF00271 Helicase conserved C-terminal domain 440 551 7.1E-18 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS09290 4edfe1095a352a5cb30204a634abf0b4 701 SMART SM00487 18 433 3.4E-25 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CFK41_RS09290 4edfe1095a352a5cb30204a634abf0b4 701 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 14 691 0.0 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CFK41_RS14070 3860925ce7c6ee344be81e039c5c6bf9 233 Gene3D G3DSA:1.10.10.10 1 68 4.4E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS14070 3860925ce7c6ee344be81e039c5c6bf9 233 SUPERFAMILY SSF46785 1 63 3.12E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS14070 3860925ce7c6ee344be81e039c5c6bf9 233 Pfam PF13280 WYL domain 140 213 1.6E-15 T 28-03-2018 IPR026881 WYL domain CFK41_RS14070 3860925ce7c6ee344be81e039c5c6bf9 233 Pfam PF08279 HTH domain 6 62 7.9E-14 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CFK41_RS08760 968bf348140a8f500ba74d3c06278035 251 SUPERFAMILY SSF53448 6 222 6.43E-35 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS08760 968bf348140a8f500ba74d3c06278035 251 Gene3D G3DSA:3.90.550.10 2 248 1.0E-33 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS08760 968bf348140a8f500ba74d3c06278035 251 Pfam PF00535 Glycosyl transferase family 2 13 178 9.0E-26 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CFK41_RS04645 ee7c5badc8694b9b2deaa46c4210778b 189 PIRSF PIRSF002161 6 189 1.7E-64 T 28-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04645 ee7c5badc8694b9b2deaa46c4210778b 189 Pfam PF00673 ribosomal L5P family C-terminus 93 186 1.4E-38 T 28-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04645 ee7c5badc8694b9b2deaa46c4210778b 189 Pfam PF00281 Ribosomal protein L5 33 89 4.1E-27 T 28-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04645 ee7c5badc8694b9b2deaa46c4210778b 189 Gene3D G3DSA:3.30.1440.10 10 188 4.0E-75 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04645 ee7c5badc8694b9b2deaa46c4210778b 189 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 10 188 42.902 T 28-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS04645 ee7c5badc8694b9b2deaa46c4210778b 189 SUPERFAMILY SSF55282 12 187 4.94E-75 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS16215 1a97258f85855f8f6f1567432b520d7c 308 Gene3D G3DSA:3.10.180.10 76 239 1.2E-33 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS16215 1a97258f85855f8f6f1567432b520d7c 308 ProSitePatterns PS00934 Glyoxalase I signature 1. 187 208 - T 28-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 CFK41_RS16215 1a97258f85855f8f6f1567432b520d7c 308 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 185 279 5.6E-7 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CFK41_RS16215 1a97258f85855f8f6f1567432b520d7c 308 Gene3D G3DSA:3.10.180.10 240 304 1.1E-5 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS16215 1a97258f85855f8f6f1567432b520d7c 308 Gene3D G3DSA:3.10.180.10 2 75 0.24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS16215 1a97258f85855f8f6f1567432b520d7c 308 SUPERFAMILY SSF54593 18 305 1.01E-29 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS16215 1a97258f85855f8f6f1567432b520d7c 308 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 117 136 - T 28-03-2018 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 CFK41_RS06880 0b04d0f81c556f2ffea31cce3859633d 358 Gene3D G3DSA:1.10.40.50 287 356 1.4E-18 T 28-03-2018 CFK41_RS06880 0b04d0f81c556f2ffea31cce3859633d 358 SUPERFAMILY SSF52540 118 344 2.99E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS06880 0b04d0f81c556f2ffea31cce3859633d 358 Pfam PF03193 RsgA GTPase 101 286 1.8E-38 T 28-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 CFK41_RS06880 0b04d0f81c556f2ffea31cce3859633d 358 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 76 330 1.2E-39 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CFK41_RS06880 0b04d0f81c556f2ffea31cce3859633d 358 Gene3D G3DSA:3.40.50.300 115 286 2.9E-18 T 28-03-2018 CFK41_RS06880 0b04d0f81c556f2ffea31cce3859633d 358 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 36 354 27.204 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CFK41_RS09200 bf0df766aabc5f72085377af8577792d 517 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 33 516 1.3E-189 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CFK41_RS09200 bf0df766aabc5f72085377af8577792d 517 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 35 218 9.5E-58 T 28-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CFK41_RS09200 bf0df766aabc5f72085377af8577792d 517 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 198 226 1.9E-46 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CFK41_RS09200 bf0df766aabc5f72085377af8577792d 517 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 250 267 1.9E-46 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CFK41_RS09200 bf0df766aabc5f72085377af8577792d 517 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 357 383 1.9E-46 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CFK41_RS09200 bf0df766aabc5f72085377af8577792d 517 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 174 187 1.9E-46 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CFK41_RS09200 bf0df766aabc5f72085377af8577792d 517 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 268 284 1.9E-46 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CFK41_RS09200 bf0df766aabc5f72085377af8577792d 517 SUPERFAMILY SSF51735 22 221 1.24E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS09200 bf0df766aabc5f72085377af8577792d 517 SUPERFAMILY SSF55347 208 515 7.52E-109 T 28-03-2018 CFK41_RS09200 bf0df766aabc5f72085377af8577792d 517 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 208 214 - T 28-03-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CFK41_RS09200 bf0df766aabc5f72085377af8577792d 517 Gene3D G3DSA:3.30.360.10 220 517 1.2E-120 T 28-03-2018 CFK41_RS09200 bf0df766aabc5f72085377af8577792d 517 PIRSF PIRSF000110 19 517 1.8E-172 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CFK41_RS09200 bf0df766aabc5f72085377af8577792d 517 Gene3D G3DSA:3.40.50.720 30 219 3.9E-63 T 28-03-2018 CFK41_RS09200 bf0df766aabc5f72085377af8577792d 517 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 31 516 83.876 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CFK41_RS09200 bf0df766aabc5f72085377af8577792d 517 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 220 515 1.1E-107 T 28-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CFK41_RS12490 f4baf0a524f7a311bd87e1fc7e88b4fe 576 SUPERFAMILY SSF52540 70 456 2.26E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS12490 f4baf0a524f7a311bd87e1fc7e88b4fe 576 Pfam PF05872 Bacterial protein of unknown function (DUF853) 85 573 3.3E-183 T 28-03-2018 IPR033186 Helicase HerA-like C-terminal CFK41_RS12490 f4baf0a524f7a311bd87e1fc7e88b4fe 576 Gene3D G3DSA:3.40.50.300 48 428 7.8E-27 T 28-03-2018 CFK41_RS00670 bf742b83fdebbad2d239e749ab8d0386 179 Gene3D G3DSA:2.40.33.20 1 179 2.0E-43 T 28-03-2018 CFK41_RS00670 bf742b83fdebbad2d239e749ab8d0386 179 Pfam PF03473 MOSC domain 57 164 2.5E-8 T 28-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 CFK41_RS00670 bf742b83fdebbad2d239e749ab8d0386 179 SUPERFAMILY SSF50800 2 168 3.51E-39 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain CFK41_RS03560 55d6436bcfd3f6052b81d38c2f982e98 375 Gene3D G3DSA:3.30.70.1400 174 266 3.8E-12 T 28-03-2018 CFK41_RS03560 55d6436bcfd3f6052b81d38c2f982e98 375 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 253 336 7.3E-9 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CFK41_RS03560 55d6436bcfd3f6052b81d38c2f982e98 375 SUPERFAMILY SSF103025 26 268 1.73E-42 T 28-03-2018 CFK41_RS03560 55d6436bcfd3f6052b81d38c2f982e98 375 Gene3D G3DSA:2.40.30.110 268 343 5.2E-13 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CFK41_RS03560 55d6436bcfd3f6052b81d38c2f982e98 375 PIRSF PIRSF006487 20 159 5.9E-6 T 28-03-2018 CFK41_RS03560 55d6436bcfd3f6052b81d38c2f982e98 375 PIRSF PIRSF006487 191 355 3.6E-5 T 28-03-2018 CFK41_RS03560 55d6436bcfd3f6052b81d38c2f982e98 375 Gene3D G3DSA:3.30.70.1400 52 139 8.7E-16 T 28-03-2018 CFK41_RS03560 55d6436bcfd3f6052b81d38c2f982e98 375 Pfam PF01571 Aminomethyltransferase folate-binding domain 25 142 3.0E-13 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal CFK41_RS03560 55d6436bcfd3f6052b81d38c2f982e98 375 SUPERFAMILY SSF101790 272 338 5.07E-6 T 28-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain CFK41_RS03560 55d6436bcfd3f6052b81d38c2f982e98 375 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 215 279 6.1E-18 T 28-03-2018 IPR017703 YgfZ/GcvT conserved site CFK41_RS05300 82e089577bda69daf42a16903548c86b 255 SMART SM00014 111 233 0.0042 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CFK41_RS05300 82e089577bda69daf42a16903548c86b 255 Pfam PF01569 PAP2 superfamily 156 240 1.0E-9 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CFK41_RS05300 82e089577bda69daf42a16903548c86b 255 SUPERFAMILY SSF48317 26 241 1.14E-14 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CFK41_RS05300 82e089577bda69daf42a16903548c86b 255 Gene3D G3DSA:1.20.144.10 16 249 2.5E-10 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CFK41_RS15775 ad7cc201d05fea61828413f1620db2a7 452 PIRSF PIRSF006603 10 451 8.1E-52 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CFK41_RS15775 ad7cc201d05fea61828413f1620db2a7 452 Pfam PF01554 MatE 248 392 1.0E-13 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CFK41_RS15775 ad7cc201d05fea61828413f1620db2a7 452 Pfam PF01554 MatE 30 189 3.2E-25 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CFK41_RS15775 ad7cc201d05fea61828413f1620db2a7 452 TIGRFAM TIGR00797 matE: MATE efflux family protein 30 409 7.6E-82 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CFK41_RS00360 47bb75b238e1f563a70f0c238a7821e6 227 Pfam PF04023 FeoA domain 150 220 5.9E-11 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CFK41_RS00360 47bb75b238e1f563a70f0c238a7821e6 227 Gene3D G3DSA:2.30.30.90 129 223 6.4E-22 T 28-03-2018 CFK41_RS00360 47bb75b238e1f563a70f0c238a7821e6 227 SUPERFAMILY SSF46785 6 67 1.31E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS00360 47bb75b238e1f563a70f0c238a7821e6 227 SMART SM00899 148 223 1.1E-6 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CFK41_RS00360 47bb75b238e1f563a70f0c238a7821e6 227 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 70 136 8.7E-29 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CFK41_RS00360 47bb75b238e1f563a70f0c238a7821e6 227 SUPERFAMILY SSF47979 69 140 1.83E-25 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CFK41_RS00360 47bb75b238e1f563a70f0c238a7821e6 227 Gene3D G3DSA:1.10.10.10 2 83 1.6E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS00360 47bb75b238e1f563a70f0c238a7821e6 227 Gene3D G3DSA:1.10.60.10 84 128 6.2E-24 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CFK41_RS00360 47bb75b238e1f563a70f0c238a7821e6 227 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 5 64 1.2E-14 T 28-03-2018 IPR022687 DTXR-type HTH domain GO:0003677 CFK41_RS00360 47bb75b238e1f563a70f0c238a7821e6 227 SMART SM00529 29 128 3.8E-35 T 28-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 CFK41_RS00360 47bb75b238e1f563a70f0c238a7821e6 227 SUPERFAMILY SSF50037 133 222 4.27E-5 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal CFK41_RS13430 9b8fb7e135ab21148642b9d512d50a7c 379 PRINTS PR00084 Mannitol dehydrogenase signature 3 13 2.4E-13 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CFK41_RS13430 9b8fb7e135ab21148642b9d512d50a7c 379 PRINTS PR00084 Mannitol dehydrogenase signature 165 180 2.4E-13 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CFK41_RS13430 9b8fb7e135ab21148642b9d512d50a7c 379 PRINTS PR00084 Mannitol dehydrogenase signature 114 127 2.4E-13 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CFK41_RS13430 9b8fb7e135ab21148642b9d512d50a7c 379 PRINTS PR00084 Mannitol dehydrogenase signature 147 160 2.4E-13 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CFK41_RS13430 9b8fb7e135ab21148642b9d512d50a7c 379 SUPERFAMILY SSF48179 199 372 5.78E-40 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CFK41_RS13430 9b8fb7e135ab21148642b9d512d50a7c 379 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 147 365 1.7E-45 T 28-03-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 CFK41_RS13430 9b8fb7e135ab21148642b9d512d50a7c 379 Gene3D G3DSA:1.10.1040.10 202 375 2.0E-40 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CFK41_RS13430 9b8fb7e135ab21148642b9d512d50a7c 379 SUPERFAMILY SSF51735 1 198 5.97E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS13430 9b8fb7e135ab21148642b9d512d50a7c 379 Gene3D G3DSA:3.40.50.720 80 192 3.7E-20 T 28-03-2018 CFK41_RS13430 9b8fb7e135ab21148642b9d512d50a7c 379 Gene3D G3DSA:3.40.50.720 1 79 1.4E-9 T 28-03-2018 CFK41_RS13430 9b8fb7e135ab21148642b9d512d50a7c 379 Hamap MF_00196 Mannitol-1-phosphate 5-dehydrogenase [mtlD]. 1 373 34.46 T 28-03-2018 IPR023028 Mannitol-1-phosphate 5-dehydrogenase GO:0008926|GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CFK41_RS13430 9b8fb7e135ab21148642b9d512d50a7c 379 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 1 122 9.1E-18 T 28-03-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 CFK41_RS06335 edd788dfe1da85b42ca5c0a309ef889f 231 SMART SM00448 8 118 2.5E-50 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS06335 edd788dfe1da85b42ca5c0a309ef889f 231 Pfam PF00072 Response regulator receiver domain 10 119 2.0E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS06335 edd788dfe1da85b42ca5c0a309ef889f 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 226 2.5E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CFK41_RS06335 edd788dfe1da85b42ca5c0a309ef889f 231 SUPERFAMILY SSF52172 4 131 3.7E-45 T 28-03-2018 IPR011006 CheY-like superfamily CFK41_RS06335 edd788dfe1da85b42ca5c0a309ef889f 231 Gene3D G3DSA:1.10.10.10 126 228 2.0E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS06335 edd788dfe1da85b42ca5c0a309ef889f 231 SUPERFAMILY SSF46894 127 226 1.05E-28 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CFK41_RS06335 edd788dfe1da85b42ca5c0a309ef889f 231 Gene3D G3DSA:3.40.50.2300 1 125 3.6E-41 T 28-03-2018 CFK41_RS06335 edd788dfe1da85b42ca5c0a309ef889f 231 SMART SM00862 151 227 1.9E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CFK41_RS10640 22a19fb73ee9425b883fab73531c2497 337 SUPERFAMILY SSF161098 95 318 3.4E-57 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS10640 22a19fb73ee9425b883fab73531c2497 337 SUPERFAMILY SSF160964 55 92 3.66E-6 T 28-03-2018 CFK41_RS10640 22a19fb73ee9425b883fab73531c2497 337 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 329 5.1E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS10640 22a19fb73ee9425b883fab73531c2497 337 Gene3D G3DSA:1.10.3720.10 54 335 9.6E-52 T 28-03-2018 CFK41_RS00690 2bb191ef18b1fe693b67959e633d0c26 513 SUPERFAMILY SSF48557 2 502 6.59E-171 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CFK41_RS00690 2bb191ef18b1fe693b67959e633d0c26 513 Gene3D G3DSA:1.20.200.10 202 512 1.2E-111 T 28-03-2018 CFK41_RS00690 2bb191ef18b1fe693b67959e633d0c26 513 Pfam PF00221 Aromatic amino acid lyase 12 473 8.7E-175 T 28-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 CFK41_RS00690 2bb191ef18b1fe693b67959e633d0c26 513 Gene3D G3DSA:1.10.275.10 1 200 4.7E-70 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CFK41_RS00690 2bb191ef18b1fe693b67959e633d0c26 513 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 5 506 8.6E-190 T 28-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CFK41_RS00690 2bb191ef18b1fe693b67959e633d0c26 513 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 141 156 - T 28-03-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 CFK41_RS04675 776124a894b3b78080c1a25a9e51e453 59 Pfam PF00327 Ribosomal protein L30p/L7e 3 53 7.1E-18 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CFK41_RS04675 776124a894b3b78080c1a25a9e51e453 59 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 57 19.671 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04675 776124a894b3b78080c1a25a9e51e453 59 SUPERFAMILY SSF55129 3 59 2.88E-20 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CFK41_RS04675 776124a894b3b78080c1a25a9e51e453 59 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 3 57 5.0E-25 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04675 776124a894b3b78080c1a25a9e51e453 59 Gene3D G3DSA:3.30.1390.20 3 57 1.5E-22 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CFK41_RS04675 776124a894b3b78080c1a25a9e51e453 59 PIRSF PIRSF002211 1 59 6.3E-27 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS11630 1f624c6da2627112b5b037b09bf4dad1 229 Gene3D G3DSA:1.10.10.10 56 114 4.3E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS11630 1f624c6da2627112b5b037b09bf4dad1 229 Hamap MF_01114 Regulatory protein RecX [recX]. 61 223 11.847 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CFK41_RS11630 1f624c6da2627112b5b037b09bf4dad1 229 Gene3D G3DSA:1.10.10.10 160 217 0.5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS11630 1f624c6da2627112b5b037b09bf4dad1 229 Gene3D G3DSA:1.10.10.10 115 158 2.0E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS11630 1f624c6da2627112b5b037b09bf4dad1 229 Pfam PF02631 RecX family 91 217 2.2E-19 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CFK41_RS16655 abcb3f115527f10dd5e6f02902acbb83 423 Gene3D G3DSA:3.20.20.80 2 308 1.9E-86 T 28-03-2018 CFK41_RS16655 abcb3f115527f10dd5e6f02902acbb83 423 SMART SM00812 6 340 2.0E-22 T 28-03-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS16655 abcb3f115527f10dd5e6f02902acbb83 423 Pfam PF01120 Alpha-L-fucosidase 15 303 1.2E-38 T 28-03-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS16655 abcb3f115527f10dd5e6f02902acbb83 423 SUPERFAMILY SSF51445 3 304 7.37E-88 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS16655 abcb3f115527f10dd5e6f02902acbb83 423 PRINTS PR00741 Glycosyl hydrolase family 29 signature 261 282 6.0E-7 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS16655 abcb3f115527f10dd5e6f02902acbb83 423 PRINTS PR00741 Glycosyl hydrolase family 29 signature 68 84 6.0E-7 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS09395 2d78e69876bf895743ddd6fc4501fef5 298 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 190 218 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CFK41_RS09395 2d78e69876bf895743ddd6fc4501fef5 298 SUPERFAMILY SSF51735 52 294 1.55E-76 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS09395 2d78e69876bf895743ddd6fc4501fef5 298 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 203 222 6.7E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS09395 2d78e69876bf895743ddd6fc4501fef5 298 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 142 6.7E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS09395 2d78e69876bf895743ddd6fc4501fef5 298 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 183 191 6.7E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS09395 2d78e69876bf895743ddd6fc4501fef5 298 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 60 294 4.4E-60 T 28-03-2018 CFK41_RS09395 2d78e69876bf895743ddd6fc4501fef5 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 55 72 8.1E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS09395 2d78e69876bf895743ddd6fc4501fef5 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 222 8.1E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS09395 2d78e69876bf895743ddd6fc4501fef5 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 241 8.1E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS09395 2d78e69876bf895743ddd6fc4501fef5 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 142 8.1E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS09395 2d78e69876bf895743ddd6fc4501fef5 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 193 8.1E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS09395 2d78e69876bf895743ddd6fc4501fef5 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 259 279 8.1E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS09395 2d78e69876bf895743ddd6fc4501fef5 298 Gene3D G3DSA:3.40.50.720 6 296 2.6E-75 T 28-03-2018 CFK41_RS07725 ebe5ff76778d5de7c484fb9491abeee2 334 SUPERFAMILY SSF161098 90 318 2.09E-48 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS07725 ebe5ff76778d5de7c484fb9491abeee2 334 Gene3D G3DSA:1.10.3720.10 46 333 2.2E-41 T 28-03-2018 CFK41_RS07725 ebe5ff76778d5de7c484fb9491abeee2 334 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 327 6.2E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS11370 92459798d8682f458077794b404a472c 640 Pfam PF00679 Elongation factor G C-terminus 429 512 6.4E-22 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CFK41_RS11370 92459798d8682f458077794b404a472c 640 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 9 631 1.6E-265 T 28-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 CFK41_RS11370 92459798d8682f458077794b404a472c 640 PRINTS PR00315 GTP-binding elongation factor signature 86 96 3.5E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS11370 92459798d8682f458077794b404a472c 640 PRINTS PR00315 GTP-binding elongation factor signature 138 147 3.5E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS11370 92459798d8682f458077794b404a472c 640 PRINTS PR00315 GTP-binding elongation factor signature 11 24 3.5E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS11370 92459798d8682f458077794b404a472c 640 PRINTS PR00315 GTP-binding elongation factor signature 55 63 3.5E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS11370 92459798d8682f458077794b404a472c 640 PRINTS PR00315 GTP-binding elongation factor signature 102 113 3.5E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS11370 92459798d8682f458077794b404a472c 640 SUPERFAMILY SSF52540 6 198 3.73E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11370 92459798d8682f458077794b404a472c 640 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 158 9.3E-23 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CFK41_RS11370 92459798d8682f458077794b404a472c 640 SMART SM00838 428 516 0.0029 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CFK41_RS11370 92459798d8682f458077794b404a472c 640 SUPERFAMILY SSF54980 334 420 1.53E-10 T 28-03-2018 IPR035647 EF-G domain III/V-like CFK41_RS11370 92459798d8682f458077794b404a472c 640 Gene3D G3DSA:3.30.70.240 435 512 5.2E-18 T 28-03-2018 CFK41_RS11370 92459798d8682f458077794b404a472c 640 Gene3D G3DSA:3.30.70.870 333 434 1.3E-28 T 28-03-2018 CFK41_RS11370 92459798d8682f458077794b404a472c 640 Gene3D G3DSA:2.40.50.250 515 605 6.1E-35 T 28-03-2018 CFK41_RS11370 92459798d8682f458077794b404a472c 640 SUPERFAMILY SSF50447 213 331 8.84E-24 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CFK41_RS11370 92459798d8682f458077794b404a472c 640 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 48 63 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CFK41_RS11370 92459798d8682f458077794b404a472c 640 Gene3D G3DSA:2.40.30.10 208 331 1.6E-17 T 28-03-2018 CFK41_RS11370 92459798d8682f458077794b404a472c 640 Pfam PF00009 Elongation factor Tu GTP binding domain 9 225 1.5E-50 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS11370 92459798d8682f458077794b404a472c 640 Gene3D G3DSA:3.40.50.300 4 207 2.4E-34 T 28-03-2018 CFK41_RS11370 92459798d8682f458077794b404a472c 640 SUPERFAMILY SSF54980 431 545 6.71E-27 T 28-03-2018 IPR035647 EF-G domain III/V-like CFK41_RS05195 7157c4356a7dd19a3f1edb826946cb35 70 Gene3D G3DSA:1.10.260.40 2 70 1.1E-12 T 28-03-2018 CFK41_RS05195 7157c4356a7dd19a3f1edb826946cb35 70 SUPERFAMILY SSF47413 2 67 2.1E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS05195 7157c4356a7dd19a3f1edb826946cb35 70 SMART SM00530 6 62 7.7E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CFK41_RS05195 7157c4356a7dd19a3f1edb826946cb35 70 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 68 4.2E-21 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CFK41_RS17235 cc496f6857159b5998666fce4306e542 405 Pfam PF03825 Nucleoside H+ symporter 7 399 3.9E-119 T 28-03-2018 CFK41_RS17235 cc496f6857159b5998666fce4306e542 405 Gene3D G3DSA:1.20.1250.20 7 194 2.4E-14 T 28-03-2018 CFK41_RS17235 cc496f6857159b5998666fce4306e542 405 Gene3D G3DSA:1.20.1250.20 201 403 8.0E-25 T 28-03-2018 CFK41_RS17235 cc496f6857159b5998666fce4306e542 405 SUPERFAMILY SSF103473 9 398 4.05E-41 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS14010 9530cab8022c88c7b47ac78f36b0b61f 446 ProSitePatterns PS00216 Sugar transport proteins signature 1. 317 334 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CFK41_RS14010 9530cab8022c88c7b47ac78f36b0b61f 446 SUPERFAMILY SSF103473 38 442 6.28E-46 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS14010 9530cab8022c88c7b47ac78f36b0b61f 446 Gene3D G3DSA:1.20.1250.20 246 444 2.9E-25 T 28-03-2018 CFK41_RS14010 9530cab8022c88c7b47ac78f36b0b61f 446 Gene3D G3DSA:1.20.1250.20 35 245 1.6E-18 T 28-03-2018 CFK41_RS14010 9530cab8022c88c7b47ac78f36b0b61f 446 Pfam PF07690 Major Facilitator Superfamily 265 441 4.4E-17 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS04460 29978c1ddff50e514b377a4be8580a54 419 PRINTS PR00959 Mevalonate kinase family signature 364 381 1.3E-37 T 28-03-2018 CFK41_RS04460 29978c1ddff50e514b377a4be8580a54 419 PRINTS PR00959 Mevalonate kinase family signature 149 171 1.3E-37 T 28-03-2018 CFK41_RS04460 29978c1ddff50e514b377a4be8580a54 419 PRINTS PR00959 Mevalonate kinase family signature 192 211 1.3E-37 T 28-03-2018 CFK41_RS04460 29978c1ddff50e514b377a4be8580a54 419 PRINTS PR00959 Mevalonate kinase family signature 55 79 1.3E-37 T 28-03-2018 CFK41_RS04460 29978c1ddff50e514b377a4be8580a54 419 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 151 162 - T 28-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 CFK41_RS04460 29978c1ddff50e514b377a4be8580a54 419 TIGRFAM TIGR00131 gal_kin: galactokinase 37 400 4.6E-85 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CFK41_RS04460 29978c1ddff50e514b377a4be8580a54 419 Gene3D G3DSA:3.30.230.10 32 239 9.8E-56 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CFK41_RS04460 29978c1ddff50e514b377a4be8580a54 419 Gene3D G3DSA:3.30.70.890 240 417 3.6E-52 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CFK41_RS04460 29978c1ddff50e514b377a4be8580a54 419 ProSitePatterns PS00106 Galactokinase signature. 57 68 - T 28-03-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CFK41_RS04460 29978c1ddff50e514b377a4be8580a54 419 SUPERFAMILY SSF55060 237 416 2.7E-49 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CFK41_RS04460 29978c1ddff50e514b377a4be8580a54 419 SUPERFAMILY SSF54211 35 232 3.26E-53 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CFK41_RS04460 29978c1ddff50e514b377a4be8580a54 419 PIRSF PIRSF000530 23 417 1.4E-116 T 28-03-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CFK41_RS04460 29978c1ddff50e514b377a4be8580a54 419 Pfam PF00288 GHMP kinases N terminal domain 144 210 1.5E-13 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CFK41_RS04460 29978c1ddff50e514b377a4be8580a54 419 Pfam PF10509 Galactokinase galactose-binding signature 40 87 4.1E-20 T 28-03-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CFK41_RS04460 29978c1ddff50e514b377a4be8580a54 419 PRINTS PR00473 Galactokinase signature 57 75 9.7E-23 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CFK41_RS04460 29978c1ddff50e514b377a4be8580a54 419 PRINTS PR00473 Galactokinase signature 142 160 9.7E-23 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CFK41_RS04460 29978c1ddff50e514b377a4be8580a54 419 PRINTS PR00473 Galactokinase signature 120 131 9.7E-23 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CFK41_RS04460 29978c1ddff50e514b377a4be8580a54 419 PRINTS PR00473 Galactokinase signature 297 311 9.7E-23 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CFK41_RS04460 29978c1ddff50e514b377a4be8580a54 419 Pfam PF08544 GHMP kinases C terminal 323 397 9.8E-14 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CFK41_RS04710 bd9c68733b28a72fa01e3a26f688d2fe 124 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 28-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04710 bd9c68733b28a72fa01e3a26f688d2fe 124 Gene3D G3DSA:4.10.910.10 87 122 1.7E-24 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04710 bd9c68733b28a72fa01e3a26f688d2fe 124 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 120 26.766 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04710 bd9c68733b28a72fa01e3a26f688d2fe 124 Gene3D G3DSA:1.10.8.50 1 67 4.9E-18 T 28-03-2018 CFK41_RS04710 bd9c68733b28a72fa01e3a26f688d2fe 124 Pfam PF00416 Ribosomal protein S13/S18 3 109 6.2E-30 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04710 bd9c68733b28a72fa01e3a26f688d2fe 124 Gene3D G3DSA:4.10.910.10 68 86 6.2E-15 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04710 bd9c68733b28a72fa01e3a26f688d2fe 124 PIRSF PIRSF002134 1 124 5.8E-40 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04710 bd9c68733b28a72fa01e3a26f688d2fe 124 SUPERFAMILY SSF46946 2 121 1.85E-41 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CFK41_RS04710 bd9c68733b28a72fa01e3a26f688d2fe 124 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 5.8E-48 T 28-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS11875 7b7f822095c130abb4a32d1ddaa7b44b 100 Pfam PF10611 Protein of unknown function (DUF2469) 2 100 6.8E-51 T 28-03-2018 IPR019592 Protein of unknown function DUF2469 CFK41_RS16325 4beffc6fa0fdd52eb865681c4ea30672 425 SUPERFAMILY SSF51445 35 335 1.14E-58 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS16325 4beffc6fa0fdd52eb865681c4ea30672 425 Gene3D G3DSA:3.20.20.80 36 349 2.8E-48 T 28-03-2018 CFK41_RS16325 4beffc6fa0fdd52eb865681c4ea30672 425 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 93 329 8.4E-25 T 28-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 CFK41_RS10590 177e3f1ca71927f22f4e29863324d9e9 659 Pfam PF13193 AMP-binding enzyme C-terminal domain 536 621 3.1E-26 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CFK41_RS10590 177e3f1ca71927f22f4e29863324d9e9 659 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 14 655 50.447 T 28-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 CFK41_RS10590 177e3f1ca71927f22f4e29863324d9e9 659 Gene3D G3DSA:3.30.300.30 521 640 8.7E-27 T 28-03-2018 CFK41_RS10590 177e3f1ca71927f22f4e29863324d9e9 659 Gene3D G3DSA:3.40.50.980 271 435 8.8E-36 T 28-03-2018 CFK41_RS10590 177e3f1ca71927f22f4e29863324d9e9 659 SUPERFAMILY SSF56801 31 652 3.53E-172 T 28-03-2018 CFK41_RS10590 177e3f1ca71927f22f4e29863324d9e9 659 ProSitePatterns PS00455 Putative AMP-binding domain signature. 265 276 - T 28-03-2018 IPR020845 AMP-binding, conserved site CFK41_RS10590 177e3f1ca71927f22f4e29863324d9e9 659 Pfam PF00501 AMP-binding enzyme 94 527 2.8E-94 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CFK41_RS10590 177e3f1ca71927f22f4e29863324d9e9 659 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 34 86 2.3E-19 T 28-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 CFK41_RS10590 177e3f1ca71927f22f4e29863324d9e9 659 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 31 653 1.4E-287 T 28-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 CFK41_RS10590 177e3f1ca71927f22f4e29863324d9e9 659 Gene3D G3DSA:2.30.38.10 436 520 6.0E-14 T 28-03-2018 CFK41_RS10590 177e3f1ca71927f22f4e29863324d9e9 659 Gene3D G3DSA:3.40.50.980 79 270 1.0E-49 T 28-03-2018 CFK41_RS05695 18fec96ce2705bd48cecbb22c40e2888 126 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 26.949 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS05695 18fec96ce2705bd48cecbb22c40e2888 126 Pfam PF00453 Ribosomal protein L20 3 109 1.4E-41 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS05695 18fec96ce2705bd48cecbb22c40e2888 126 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 72 4.0E-19 T 28-03-2018 CFK41_RS05695 18fec96ce2705bd48cecbb22c40e2888 126 PRINTS PR00062 Ribosomal protein L20 signature 42 71 6.3E-35 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS05695 18fec96ce2705bd48cecbb22c40e2888 126 PRINTS PR00062 Ribosomal protein L20 signature 12 41 6.3E-35 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS05695 18fec96ce2705bd48cecbb22c40e2888 126 PRINTS PR00062 Ribosomal protein L20 signature 75 101 6.3E-35 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS05695 18fec96ce2705bd48cecbb22c40e2888 126 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 2 114 3.9E-42 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS05695 18fec96ce2705bd48cecbb22c40e2888 126 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS05695 18fec96ce2705bd48cecbb22c40e2888 126 Gene3D G3DSA:1.10.1900.20 56 116 1.7E-23 T 28-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS05695 18fec96ce2705bd48cecbb22c40e2888 126 SUPERFAMILY SSF74731 3 117 1.15E-43 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04745 a1a9d49a5a7228c1dfefde11ab6c7355 300 SUPERFAMILY SSF53613 1 296 1.56E-75 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS04745 a1a9d49a5a7228c1dfefde11ab6c7355 300 Pfam PF00294 pfkB family carbohydrate kinase 2 290 2.3E-60 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CFK41_RS04745 a1a9d49a5a7228c1dfefde11ab6c7355 300 PRINTS PR00990 Ribokinase signature 172 187 7.8E-31 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CFK41_RS04745 a1a9d49a5a7228c1dfefde11ab6c7355 300 PRINTS PR00990 Ribokinase signature 32 51 7.8E-31 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CFK41_RS04745 a1a9d49a5a7228c1dfefde11ab6c7355 300 PRINTS PR00990 Ribokinase signature 103 116 7.8E-31 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CFK41_RS04745 a1a9d49a5a7228c1dfefde11ab6c7355 300 PRINTS PR00990 Ribokinase signature 5 26 7.8E-31 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CFK41_RS04745 a1a9d49a5a7228c1dfefde11ab6c7355 300 PRINTS PR00990 Ribokinase signature 216 227 7.8E-31 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CFK41_RS04745 a1a9d49a5a7228c1dfefde11ab6c7355 300 Gene3D G3DSA:3.40.1190.20 1 300 3.2E-70 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS04745 a1a9d49a5a7228c1dfefde11ab6c7355 300 Hamap MF_01987 Ribokinase [rbsK]. 1 300 24.998 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CFK41_RS04745 a1a9d49a5a7228c1dfefde11ab6c7355 300 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 3 296 2.3E-103 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CFK41_RS05200 9e67ac3b09e1a56c973072a79225ff5e 176 Pfam PF11188 Protein of unknown function (DUF2975) 41 176 1.9E-13 T 28-03-2018 IPR021354 Protein of unknown function DUF2975 CFK41_RS07525 feeac0206a39245074a6e900fed8565a 84 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 81 3.3E-35 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS07525 feeac0206a39245074a6e900fed8565a 84 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 70 3.0E-13 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS07525 feeac0206a39245074a6e900fed8565a 84 Pfam PF01016 Ribosomal L27 protein 2 80 1.9E-35 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS07525 feeac0206a39245074a6e900fed8565a 84 Gene3D G3DSA:2.40.50.100 20 83 4.1E-27 T 28-03-2018 CFK41_RS07525 feeac0206a39245074a6e900fed8565a 84 PRINTS PR00063 Ribosomal protein L27 signature 4 28 1.1E-35 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS07525 feeac0206a39245074a6e900fed8565a 84 PRINTS PR00063 Ribosomal protein L27 signature 29 53 1.1E-35 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS07525 feeac0206a39245074a6e900fed8565a 84 PRINTS PR00063 Ribosomal protein L27 signature 54 78 1.1E-35 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS07525 feeac0206a39245074a6e900fed8565a 84 SUPERFAMILY SSF110324 2 81 1.22E-30 T 28-03-2018 CFK41_RS07525 feeac0206a39245074a6e900fed8565a 84 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 83 26.989 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS07525 feeac0206a39245074a6e900fed8565a 84 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 28-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS05680 e5458caa547dd497d2a46a40c2c0d468 327 Gene3D G3DSA:2.60.40.1240 200 319 5.7E-6 T 28-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CFK41_RS04770 4010cf988589eea876942b49551f1666 775 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 775 294.642 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CFK41_RS04770 4010cf988589eea876942b49551f1666 775 SUPERFAMILY SSF56042 603 774 7.48E-33 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CFK41_RS04770 4010cf988589eea876942b49551f1666 775 Gene3D G3DSA:3.30.1330.10 444 597 9.7E-45 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CFK41_RS04770 4010cf988589eea876942b49551f1666 775 Pfam PF02769 AIR synthase related protein, C-terminal domain 227 380 1.1E-30 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CFK41_RS04770 4010cf988589eea876942b49551f1666 775 Pfam PF02769 AIR synthase related protein, C-terminal domain 611 746 3.4E-14 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CFK41_RS04770 4010cf988589eea876942b49551f1666 775 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 38 765 5.6E-253 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CFK41_RS04770 4010cf988589eea876942b49551f1666 775 Gene3D G3DSA:3.90.650.10 204 396 4.1E-34 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CFK41_RS04770 4010cf988589eea876942b49551f1666 775 SUPERFAMILY SSF55326 33 219 7.18E-48 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CFK41_RS04770 4010cf988589eea876942b49551f1666 775 SUPERFAMILY SSF56042 226 455 1.15E-48 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CFK41_RS04770 4010cf988589eea876942b49551f1666 775 SUPERFAMILY SSF55326 424 599 3.4E-54 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CFK41_RS04770 4010cf988589eea876942b49551f1666 775 Gene3D G3DSA:3.90.650.10 600 775 1.2E-29 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CFK41_RS04770 4010cf988589eea876942b49551f1666 775 PIRSF PIRSF001587 20 775 1.0E-283 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CFK41_RS04770 4010cf988589eea876942b49551f1666 775 Pfam PF00586 AIR synthase related protein, N-terminal domain 469 592 3.7E-22 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CFK41_RS04770 4010cf988589eea876942b49551f1666 775 Pfam PF00586 AIR synthase related protein, N-terminal domain 101 214 2.8E-22 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CFK41_RS04770 4010cf988589eea876942b49551f1666 775 Gene3D G3DSA:3.30.1330.10 64 203 1.4E-45 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CFK41_RS01670 57c067705b9fc8f5fd457e59a4a49833 506 Gene3D G3DSA:2.60.40.1180 376 504 5.2E-38 T 28-03-2018 CFK41_RS01670 57c067705b9fc8f5fd457e59a4a49833 506 SUPERFAMILY SSF51011 372 502 4.32E-32 T 28-03-2018 CFK41_RS01670 57c067705b9fc8f5fd457e59a4a49833 506 Gene3D G3DSA:3.20.20.80 19 375 2.6E-108 T 28-03-2018 CFK41_RS01670 57c067705b9fc8f5fd457e59a4a49833 506 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 292 495 5.6E-37 T 28-03-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 CFK41_RS01670 57c067705b9fc8f5fd457e59a4a49833 506 SMART SM00813 292 495 1.6E-68 T 28-03-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 CFK41_RS01670 57c067705b9fc8f5fd457e59a4a49833 506 SUPERFAMILY SSF51445 19 383 7.04E-108 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS14440 baccf66a7128dbc5ab5c26ca7a08a4b9 429 Gene3D G3DSA:1.20.1250.20 14 216 2.5E-39 T 28-03-2018 CFK41_RS14440 baccf66a7128dbc5ab5c26ca7a08a4b9 429 Pfam PF07690 Major Facilitator Superfamily 28 382 1.1E-57 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS14440 baccf66a7128dbc5ab5c26ca7a08a4b9 429 SUPERFAMILY SSF103473 14 426 4.32E-75 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS14440 baccf66a7128dbc5ab5c26ca7a08a4b9 429 Gene3D G3DSA:1.20.1250.20 230 429 3.8E-18 T 28-03-2018 CFK41_RS00850 edcaa9abc497b633c194e1308452a3c2 312 SUPERFAMILY SSF54506 39 310 2.55E-68 T 28-03-2018 CFK41_RS00850 edcaa9abc497b633c194e1308452a3c2 312 Gene3D G3DSA:3.10.310.10 166 301 2.4E-34 T 28-03-2018 CFK41_RS00850 edcaa9abc497b633c194e1308452a3c2 312 Pfam PF02567 Phenazine biosynthesis-like protein 45 305 2.0E-51 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CFK41_RS00850 edcaa9abc497b633c194e1308452a3c2 312 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 40 308 1.3E-52 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CFK41_RS00850 edcaa9abc497b633c194e1308452a3c2 312 Gene3D G3DSA:3.10.310.10 37 165 1.5E-30 T 28-03-2018 CFK41_RS00850 edcaa9abc497b633c194e1308452a3c2 312 PIRSF PIRSF016184 38 312 1.3E-68 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CFK41_RS10070 4e4e884741f23ea377dd9d594e14e3d6 399 Gene3D G3DSA:3.30.420.10 8 208 4.0E-33 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CFK41_RS10070 4e4e884741f23ea377dd9d594e14e3d6 399 Gene3D G3DSA:1.10.150.80 209 321 2.4E-15 T 28-03-2018 CFK41_RS10070 4e4e884741f23ea377dd9d594e14e3d6 399 SUPERFAMILY SSF47819 210 312 1.48E-11 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 CFK41_RS10070 4e4e884741f23ea377dd9d594e14e3d6 399 Pfam PF00570 HRDC domain 227 273 2.4E-6 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CFK41_RS10070 4e4e884741f23ea377dd9d594e14e3d6 399 SUPERFAMILY SSF53098 13 203 4.13E-49 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CFK41_RS10070 4e4e884741f23ea377dd9d594e14e3d6 399 Pfam PF01612 3'-5' exonuclease 22 184 5.1E-31 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CFK41_RS10070 4e4e884741f23ea377dd9d594e14e3d6 399 SMART SM00474 18 185 2.4E-28 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CFK41_RS12500 c8b9c5efb2bd71e4f215dfd5e38eaeac 226 Gene3D G3DSA:1.10.260.40 71 133 4.7E-13 T 28-03-2018 CFK41_RS12500 c8b9c5efb2bd71e4f215dfd5e38eaeac 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 62 4.0E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS12500 c8b9c5efb2bd71e4f215dfd5e38eaeac 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 70 93 4.0E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS12500 c8b9c5efb2bd71e4f215dfd5e38eaeac 226 ProSitePatterns PS01081 TetR-type HTH domain signature. 61 92 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CFK41_RS12500 c8b9c5efb2bd71e4f215dfd5e38eaeac 226 SUPERFAMILY SSF46689 38 112 2.54E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS12500 c8b9c5efb2bd71e4f215dfd5e38eaeac 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 52 89 2.1E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS12500 c8b9c5efb2bd71e4f215dfd5e38eaeac 226 Gene3D G3DSA:1.10.10.60 36 70 4.9E-13 T 28-03-2018 CFK41_RS15105 625d9ba3d79ed5143a996672d627fe98 298 Gene3D G3DSA:1.10.3720.10 6 290 1.1E-39 T 28-03-2018 CFK41_RS15105 625d9ba3d79ed5143a996672d627fe98 298 SUPERFAMILY SSF161098 51 279 6.02E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS15105 625d9ba3d79ed5143a996672d627fe98 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 287 7.6E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS07305 3bc58c20508a703c09b173b0785c405b 333 Gene3D G3DSA:3.20.20.100 167 214 0.0011 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS07305 3bc58c20508a703c09b173b0785c405b 333 Gene3D G3DSA:1.10.287.850 1 91 1.7E-7 T 28-03-2018 CFK41_RS06850 338a9a583f4970c90ec1a2b4f9efe157 1024 Pfam PF03699 Uncharacterised protein family (UPF0182) 24 835 1.5E-257 T 28-03-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 CFK41_RS06850 338a9a583f4970c90ec1a2b4f9efe157 1024 Hamap MF_01600 UPF0182 protein . 15 914 17.665 T 28-03-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 CFK41_RS13255 14bdbebb1c23de8e833cbed2c2158ca2 545 SUPERFAMILY SSF53738 306 448 3.61E-32 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS13255 14bdbebb1c23de8e833cbed2c2158ca2 545 Gene3D G3DSA:3.40.120.10 31 217 2.2E-43 T 28-03-2018 CFK41_RS13255 14bdbebb1c23de8e833cbed2c2158ca2 545 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 210 315 7.7E-12 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS13255 14bdbebb1c23de8e833cbed2c2158ca2 545 SUPERFAMILY SSF55957 435 543 3.14E-17 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS13255 14bdbebb1c23de8e833cbed2c2158ca2 545 SUPERFAMILY SSF53738 209 316 9.3E-6 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS13255 14bdbebb1c23de8e833cbed2c2158ca2 545 SUPERFAMILY SSF53738 24 235 2.75E-46 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS13255 14bdbebb1c23de8e833cbed2c2158ca2 545 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 321 441 8.6E-29 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS13255 14bdbebb1c23de8e833cbed2c2158ca2 545 Gene3D G3DSA:3.40.120.10 218 332 2.3E-19 T 28-03-2018 CFK41_RS13255 14bdbebb1c23de8e833cbed2c2158ca2 545 Gene3D G3DSA:3.30.310.50 444 545 9.4E-17 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS13255 14bdbebb1c23de8e833cbed2c2158ca2 545 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 142 151 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS13255 14bdbebb1c23de8e833cbed2c2158ca2 545 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 39 181 1.0E-33 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS13255 14bdbebb1c23de8e833cbed2c2158ca2 545 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 490 538 1.0E-6 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS13255 14bdbebb1c23de8e833cbed2c2158ca2 545 Gene3D G3DSA:3.40.120.10 333 443 3.3E-27 T 28-03-2018 CFK41_RS13255 14bdbebb1c23de8e833cbed2c2158ca2 545 TIGRFAM TIGR01132 pgm: phosphoglucomutase, alpha-D-glucose phosphate-specific 1 543 7.7E-271 T 28-03-2018 IPR005852 Phosphoglucomutase, alpha-D-glucose specific GO:0004614|GO:0005975 KEGG: 00010+5.4.2.2|KEGG: 00030+5.4.2.2|KEGG: 00052+5.4.2.2|KEGG: 00230+5.4.2.2|KEGG: 00500+5.4.2.2|KEGG: 00520+5.4.2.2|KEGG: 00521+5.4.2.2|MetaCyc: PWY-2723|MetaCyc: PWY-3801|MetaCyc: PWY-5384|MetaCyc: PWY-5661|MetaCyc: PWY-5940|MetaCyc: PWY-5941|MetaCyc: PWY-622|MetaCyc: PWY-6317|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|MetaCyc: PWY-7343 CFK41_RS05805 45436860194f456cab884d4bbe9159e5 329 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 262 271 1.4E-24 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CFK41_RS05805 45436860194f456cab884d4bbe9159e5 329 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 128 139 1.4E-24 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CFK41_RS05805 45436860194f456cab884d4bbe9159e5 329 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 274 297 1.4E-24 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CFK41_RS05805 45436860194f456cab884d4bbe9159e5 329 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 46 65 1.4E-24 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CFK41_RS05805 45436860194f456cab884d4bbe9159e5 329 SUPERFAMILY SSF53671 2 310 9.56E-93 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CFK41_RS05805 45436860194f456cab884d4bbe9159e5 329 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 3 309 3.4E-106 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CFK41_RS05805 45436860194f456cab884d4bbe9159e5 329 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 155 307 4.4E-50 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CFK41_RS05805 45436860194f456cab884d4bbe9159e5 329 PRINTS PR00102 Ornithine carbamoyltransferase signature 228 238 9.3E-29 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CFK41_RS05805 45436860194f456cab884d4bbe9159e5 329 PRINTS PR00102 Ornithine carbamoyltransferase signature 77 90 9.3E-29 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CFK41_RS05805 45436860194f456cab884d4bbe9159e5 329 PRINTS PR00102 Ornithine carbamoyltransferase signature 44 58 9.3E-29 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CFK41_RS05805 45436860194f456cab884d4bbe9159e5 329 PRINTS PR00102 Ornithine carbamoyltransferase signature 117 131 9.3E-29 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CFK41_RS05805 45436860194f456cab884d4bbe9159e5 329 PRINTS PR00102 Ornithine carbamoyltransferase signature 288 299 9.3E-29 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CFK41_RS05805 45436860194f456cab884d4bbe9159e5 329 Gene3D G3DSA:3.40.50.1370 141 316 3.9E-51 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CFK41_RS05805 45436860194f456cab884d4bbe9159e5 329 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 2 310 73.296 T 28-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 CFK41_RS05805 45436860194f456cab884d4bbe9159e5 329 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 140 2.5E-42 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CFK41_RS05805 45436860194f456cab884d4bbe9159e5 329 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 46 53 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CFK41_RS05805 45436860194f456cab884d4bbe9159e5 329 Gene3D G3DSA:3.40.50.1370 1 140 7.4E-48 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CFK41_RS09225 d896ded48555ac453d035408bf22d9db 334 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 158 313 1.9E-70 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS09225 d896ded48555ac453d035408bf22d9db 334 SUPERFAMILY SSF51735 3 169 1.98E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS09225 d896ded48555ac453d035408bf22d9db 334 SMART SM00846 3 153 2.0E-87 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS09225 d896ded48555ac453d035408bf22d9db 334 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 103 8.5E-35 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS09225 d896ded48555ac453d035408bf22d9db 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 1.3E-38 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS09225 d896ded48555ac453d035408bf22d9db 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 174 190 1.3E-38 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS09225 d896ded48555ac453d035408bf22d9db 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 230 247 1.3E-38 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS09225 d896ded48555ac453d035408bf22d9db 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 270 285 1.3E-38 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS09225 d896ded48555ac453d035408bf22d9db 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 147 165 1.3E-38 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS09225 d896ded48555ac453d035408bf22d9db 334 Gene3D G3DSA:3.30.360.10 163 315 6.2E-69 T 28-03-2018 CFK41_RS09225 d896ded48555ac453d035408bf22d9db 334 SUPERFAMILY SSF55347 152 313 1.1E-71 T 28-03-2018 CFK41_RS09225 d896ded48555ac453d035408bf22d9db 334 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 151 158 - T 28-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS09225 d896ded48555ac453d035408bf22d9db 334 Gene3D G3DSA:3.40.50.720 1 162 3.8E-74 T 28-03-2018 CFK41_RS09225 d896ded48555ac453d035408bf22d9db 334 PIRSF PIRSF000149 1 333 2.6E-132 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS09225 d896ded48555ac453d035408bf22d9db 334 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 324 1.9E-135 T 28-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS01685 ed22e2575d32b6f8d06c2c1f3e10b927 115 Pfam PF12840 Helix-turn-helix domain 8 64 5.6E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS01685 ed22e2575d32b6f8d06c2c1f3e10b927 115 SUPERFAMILY SSF46785 1 98 9.45E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS01685 ed22e2575d32b6f8d06c2c1f3e10b927 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 2.7E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS01685 ed22e2575d32b6f8d06c2c1f3e10b927 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 2.7E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS01685 ed22e2575d32b6f8d06c2c1f3e10b927 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 2.7E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS01685 ed22e2575d32b6f8d06c2c1f3e10b927 115 SMART SM00418 8 86 4.7E-17 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS01685 ed22e2575d32b6f8d06c2c1f3e10b927 115 Gene3D G3DSA:1.10.10.10 1 109 4.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS17510 1b53294763ef9c29260456471075a5dd 293 Gene3D G3DSA:3.40.50.300 30 292 4.5E-55 T 28-03-2018 CFK41_RS17510 1b53294763ef9c29260456471075a5dd 293 Pfam PF13614 AAA domain 31 214 1.8E-52 T 28-03-2018 IPR025669 AAA domain CFK41_RS17510 1b53294763ef9c29260456471075a5dd 293 SUPERFAMILY SSF52540 31 290 3.99E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS05050 177396b51d4995bfe40892f77c037740 120 Gene3D G3DSA:1.10.10.10 19 120 3.3E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS05050 177396b51d4995bfe40892f77c037740 120 Pfam PF01638 HxlR-like helix-turn-helix 22 109 1.3E-30 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CFK41_RS05050 177396b51d4995bfe40892f77c037740 120 SUPERFAMILY SSF46785 7 114 4.49E-38 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS11240 3ff364b899beec3c7ff356df74d78f19 220 Gene3D G3DSA:1.10.357.10 63 199 3.1E-11 T 28-03-2018 CFK41_RS11240 3ff364b899beec3c7ff356df74d78f19 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 4.8E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS11240 3ff364b899beec3c7ff356df74d78f19 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 1.7E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS11240 3ff364b899beec3c7ff356df74d78f19 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 1.7E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS11240 3ff364b899beec3c7ff356df74d78f19 220 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 60 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CFK41_RS11240 3ff364b899beec3c7ff356df74d78f19 220 Gene3D G3DSA:1.10.10.60 2 62 1.9E-21 T 28-03-2018 CFK41_RS11240 3ff364b899beec3c7ff356df74d78f19 220 SUPERFAMILY SSF46689 6 85 4.0E-21 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS03955 240dae2b8b863df6765614b0575f0e01 710 Pfam PF08343 Ribonucleotide reductase N-terminal 12 93 1.7E-34 T 28-03-2018 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CFK41_RS03955 240dae2b8b863df6765614b0575f0e01 710 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 562 584 - T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CFK41_RS03955 240dae2b8b863df6765614b0575f0e01 710 Gene3D G3DSA:3.20.70.20 74 697 1.3E-163 T 28-03-2018 CFK41_RS03955 240dae2b8b863df6765614b0575f0e01 710 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 11 710 0.0 T 28-03-2018 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CFK41_RS03955 240dae2b8b863df6765614b0575f0e01 710 SUPERFAMILY SSF48168 11 170 4.32E-59 T 28-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CFK41_RS03955 240dae2b8b863df6765614b0575f0e01 710 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 95 167 3.8E-11 T 28-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CFK41_RS03955 240dae2b8b863df6765614b0575f0e01 710 SUPERFAMILY SSF51998 171 694 6.71E-187 T 28-03-2018 CFK41_RS03955 240dae2b8b863df6765614b0575f0e01 710 PRINTS PR01183 Ribonucleotide reductase large chain signature 378 389 8.6E-35 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CFK41_RS03955 240dae2b8b863df6765614b0575f0e01 710 PRINTS PR01183 Ribonucleotide reductase large chain signature 573 600 8.6E-35 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CFK41_RS03955 240dae2b8b863df6765614b0575f0e01 710 PRINTS PR01183 Ribonucleotide reductase large chain signature 489 512 8.6E-35 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CFK41_RS03955 240dae2b8b863df6765614b0575f0e01 710 PRINTS PR01183 Ribonucleotide reductase large chain signature 461 483 8.6E-35 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CFK41_RS03955 240dae2b8b863df6765614b0575f0e01 710 PRINTS PR01183 Ribonucleotide reductase large chain signature 422 445 8.6E-35 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CFK41_RS03955 240dae2b8b863df6765614b0575f0e01 710 PRINTS PR01183 Ribonucleotide reductase large chain signature 247 266 8.6E-35 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CFK41_RS03955 240dae2b8b863df6765614b0575f0e01 710 Pfam PF02867 Ribonucleotide reductase, barrel domain 172 689 3.8E-143 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CFK41_RS03955 240dae2b8b863df6765614b0575f0e01 710 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 99 692 1.7E-159 T 28-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CFK41_RS13765 da85f0b9889dd59235736ff91259031f 774 Pfam PF14323 GxGYxYP putative glycoside hydrolase C-terminal domain 550 770 1.1E-54 T 28-03-2018 IPR025832 GxGYxYP putative glycoside hydrolase, C-terminal CFK41_RS13765 da85f0b9889dd59235736ff91259031f 774 Pfam PF16216 GxGYxY sequence motif in domain of unknown function N-terminal 445 529 3.0E-11 T 28-03-2018 IPR032626 GxGYxYP putative glycoside hydrolase, N-terminal CFK41_RS13765 da85f0b9889dd59235736ff91259031f 774 Pfam PF16216 GxGYxY sequence motif in domain of unknown function N-terminal 177 308 7.8E-26 T 28-03-2018 IPR032626 GxGYxYP putative glycoside hydrolase, N-terminal CFK41_RS10620 f056cf29764ef3d55096816cefc8a90d 464 Gene3D G3DSA:3.30.1330.90 11 160 4.5E-51 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CFK41_RS10620 f056cf29764ef3d55096816cefc8a90d 464 Gene3D G3DSA:1.10.4100.10 270 448 3.1E-30 T 28-03-2018 CFK41_RS10620 f056cf29764ef3d55096816cefc8a90d 464 Pfam PF03313 Serine dehydratase alpha chain 189 453 4.9E-100 T 28-03-2018 IPR005130 Serine dehydratase-like, alpha subunit CFK41_RS10620 f056cf29764ef3d55096816cefc8a90d 464 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 3 455 3.0E-189 T 28-03-2018 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CFK41_RS10620 f056cf29764ef3d55096816cefc8a90d 464 SUPERFAMILY SSF143548 17 158 6.54E-38 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CFK41_RS10620 f056cf29764ef3d55096816cefc8a90d 464 Pfam PF03315 Serine dehydratase beta chain 4 157 8.3E-52 T 28-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CFK41_RS08315 2bd9044c49a668efe33759ecc11f4d17 224 SMART SM00421 157 220 2.0E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS08315 2bd9044c49a668efe33759ecc11f4d17 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 159 209 8.4E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS08315 2bd9044c49a668efe33759ecc11f4d17 224 SUPERFAMILY SSF46894 141 209 2.18E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CFK41_RS08315 2bd9044c49a668efe33759ecc11f4d17 224 SUPERFAMILY SSF52172 8 143 3.98E-18 T 28-03-2018 IPR011006 CheY-like superfamily CFK41_RS08315 2bd9044c49a668efe33759ecc11f4d17 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 190 2.8E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS08315 2bd9044c49a668efe33759ecc11f4d17 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 174 2.8E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS08315 2bd9044c49a668efe33759ecc11f4d17 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 202 2.8E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS08315 2bd9044c49a668efe33759ecc11f4d17 224 Gene3D G3DSA:1.10.10.10 141 224 1.8E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS08315 2bd9044c49a668efe33759ecc11f4d17 224 SMART SM00448 10 129 2.1E-4 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS08315 2bd9044c49a668efe33759ecc11f4d17 224 ProSitePatterns PS00622 LuxR-type HTH domain signature. 174 201 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS08315 2bd9044c49a668efe33759ecc11f4d17 224 Pfam PF00072 Response regulator receiver domain 12 117 6.1E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS08315 2bd9044c49a668efe33759ecc11f4d17 224 Gene3D G3DSA:3.40.50.2300 9 140 2.7E-20 T 28-03-2018 CFK41_RS08290 ab924d52a4be60ddc3496176976e20a3 408 Pfam PF01207 Dihydrouridine synthase (Dus) 40 352 2.1E-92 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CFK41_RS08290 ab924d52a4be60ddc3496176976e20a3 408 Gene3D G3DSA:3.20.20.70 34 278 1.1E-51 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS08290 ab924d52a4be60ddc3496176976e20a3 408 Gene3D G3DSA:1.10.1200.80 289 358 5.8E-19 T 28-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 CFK41_RS08290 ab924d52a4be60ddc3496176976e20a3 408 SUPERFAMILY SSF51395 38 352 3.3E-76 T 28-03-2018 CFK41_RS08290 ab924d52a4be60ddc3496176976e20a3 408 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 30 354 2.1E-105 T 28-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 CFK41_RS09545 833f17b1514abee889ce083aef85becd 211 Gene3D G3DSA:3.40.50.2020 19 205 7.0E-34 T 28-03-2018 CFK41_RS09545 833f17b1514abee889ce083aef85becd 211 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 23 202 34.661 T 28-03-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CFK41_RS09545 833f17b1514abee889ce083aef85becd 211 Pfam PF00156 Phosphoribosyl transferase domain 32 171 1.4E-21 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CFK41_RS09545 833f17b1514abee889ce083aef85becd 211 SUPERFAMILY SSF53271 26 195 5.51E-38 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CFK41_RS11230 fb1b6d5c90aff93bc7fff57d45ecdd8c 1098 Pfam PF00580 UvrD/REP helicase N-terminal domain 33 352 4.8E-42 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CFK41_RS11230 fb1b6d5c90aff93bc7fff57d45ecdd8c 1098 Pfam PF13361 UvrD-like helicase C-terminal domain 405 518 9.8E-7 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CFK41_RS11230 fb1b6d5c90aff93bc7fff57d45ecdd8c 1098 Pfam PF13361 UvrD-like helicase C-terminal domain 669 796 4.7E-18 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CFK41_RS11230 fb1b6d5c90aff93bc7fff57d45ecdd8c 1098 Gene3D G3DSA:3.90.320.10 838 1076 1.8E-19 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CFK41_RS11230 fb1b6d5c90aff93bc7fff57d45ecdd8c 1098 Pfam PF12705 PD-(D/E)XK nuclease superfamily 903 1062 2.3E-12 T 28-03-2018 CFK41_RS11230 fb1b6d5c90aff93bc7fff57d45ecdd8c 1098 Gene3D G3DSA:3.40.50.300 27 362 3.1E-42 T 28-03-2018 CFK41_RS11230 fb1b6d5c90aff93bc7fff57d45ecdd8c 1098 Gene3D G3DSA:3.40.50.300 393 837 2.5E-52 T 28-03-2018 CFK41_RS11230 fb1b6d5c90aff93bc7fff57d45ecdd8c 1098 SUPERFAMILY SSF52540 31 211 1.41E-103 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11230 fb1b6d5c90aff93bc7fff57d45ecdd8c 1098 SUPERFAMILY SSF52540 556 712 1.41E-103 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11230 fb1b6d5c90aff93bc7fff57d45ecdd8c 1098 SUPERFAMILY SSF52540 774 822 1.41E-103 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11230 fb1b6d5c90aff93bc7fff57d45ecdd8c 1098 SUPERFAMILY SSF52540 244 518 1.41E-103 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11230 fb1b6d5c90aff93bc7fff57d45ecdd8c 1098 SUPERFAMILY SSF52980 925 1078 2.52E-8 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CFK41_RS10240 ed18e1ca4e120c06d7fd67342f3f0509 178 SMART SM00347 54 156 5.1E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS10240 ed18e1ca4e120c06d7fd67342f3f0509 178 Gene3D G3DSA:1.10.10.10 9 175 4.7E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS10240 ed18e1ca4e120c06d7fd67342f3f0509 178 SUPERFAMILY SSF46785 22 167 4.73E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS10240 ed18e1ca4e120c06d7fd67342f3f0509 178 Pfam PF12802 MarR family 60 120 1.2E-9 T 28-03-2018 CFK41_RS08375 e06b9a9d8c151f4537ab823566560c7b 413 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 256 368 5.7E-30 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CFK41_RS08375 e06b9a9d8c151f4537ab823566560c7b 413 SUPERFAMILY SSF53901 6 253 3.01E-64 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CFK41_RS08375 e06b9a9d8c151f4537ab823566560c7b 413 SUPERFAMILY SSF53901 215 412 7.82E-57 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CFK41_RS08375 e06b9a9d8c151f4537ab823566560c7b 413 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6 248 3.4E-52 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CFK41_RS08375 e06b9a9d8c151f4537ab823566560c7b 413 SMART SM00825 Beta-ketoacyl synthase 8 404 3.4E-14 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CFK41_RS08375 e06b9a9d8c151f4537ab823566560c7b 413 Gene3D G3DSA:3.40.47.10 1 258 2.9E-69 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CFK41_RS08375 e06b9a9d8c151f4537ab823566560c7b 413 Gene3D G3DSA:3.40.47.10 262 412 1.7E-39 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CFK41_RS14985 9a20aef1378e47612e997da9790e000e 317 Gene3D G3DSA:1.10.10.60 212 247 0.13 T 28-03-2018 CFK41_RS14985 9a20aef1378e47612e997da9790e000e 317 SUPERFAMILY SSF46689 210 259 8.6E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS14985 9a20aef1378e47612e997da9790e000e 317 Pfam PF12833 Helix-turn-helix domain 232 309 9.3E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CFK41_RS14985 9a20aef1378e47612e997da9790e000e 317 Gene3D G3DSA:2.60.120.280 20 194 1.5E-6 T 28-03-2018 CFK41_RS14985 9a20aef1378e47612e997da9790e000e 317 SMART SM00342 226 309 4.4E-29 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CFK41_RS14985 9a20aef1378e47612e997da9790e000e 317 Pfam PF12852 Cupin 2 194 5.5E-36 T 28-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain CFK41_RS14985 9a20aef1378e47612e997da9790e000e 317 Gene3D G3DSA:1.10.10.60 261 316 1.9E-13 T 28-03-2018 CFK41_RS14985 9a20aef1378e47612e997da9790e000e 317 SUPERFAMILY SSF46689 262 311 1.58E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS03730 07fb8a7bacabfdbd498e93e52f48434b 625 Pfam PF05425 Copper resistance protein D 228 340 4.9E-15 T 28-03-2018 IPR008457 Copper resistance protein D GO:0016021 CFK41_RS03730 07fb8a7bacabfdbd498e93e52f48434b 625 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 394 618 2.5E-11 T 28-03-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related CFK41_RS07325 1b228c9f325558ae2242fff043150be1 506 SUPERFAMILY SSF52374 15 326 3.22E-98 T 28-03-2018 CFK41_RS07325 1b228c9f325558ae2242fff043150be1 506 SUPERFAMILY SSF48163 328 497 4.45E-31 T 28-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CFK41_RS07325 1b228c9f325558ae2242fff043150be1 506 PRINTS PR00987 Glutamyl-tRNA synthetase signature 18 30 2.1E-21 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CFK41_RS07325 1b228c9f325558ae2242fff043150be1 506 PRINTS PR00987 Glutamyl-tRNA synthetase signature 202 212 2.1E-21 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CFK41_RS07325 1b228c9f325558ae2242fff043150be1 506 PRINTS PR00987 Glutamyl-tRNA synthetase signature 47 60 2.1E-21 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CFK41_RS07325 1b228c9f325558ae2242fff043150be1 506 PRINTS PR00987 Glutamyl-tRNA synthetase signature 218 226 2.1E-21 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CFK41_RS07325 1b228c9f325558ae2242fff043150be1 506 PRINTS PR00987 Glutamyl-tRNA synthetase signature 32 43 2.1E-21 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CFK41_RS07325 1b228c9f325558ae2242fff043150be1 506 Gene3D G3DSA:3.40.50.620 134 259 4.1E-25 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS07325 1b228c9f325558ae2242fff043150be1 506 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 14 499 30.343 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CFK41_RS07325 1b228c9f325558ae2242fff043150be1 506 Gene3D G3DSA:1.10.10.350 402 506 3.6E-22 T 28-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CFK41_RS07325 1b228c9f325558ae2242fff043150be1 506 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 14 496 1.0E-124 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CFK41_RS07325 1b228c9f325558ae2242fff043150be1 506 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 14 330 1.3E-78 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CFK41_RS07325 1b228c9f325558ae2242fff043150be1 506 Gene3D G3DSA:3.40.50.620 15 133 2.7E-31 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS07325 1b228c9f325558ae2242fff043150be1 506 Gene3D G3DSA:1.10.1160.10 260 343 1.9E-26 T 28-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CFK41_RS07325 1b228c9f325558ae2242fff043150be1 506 Gene3D G3DSA:1.10.8.70 347 393 8.2E-10 T 28-03-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CFK41_RS09020 0c964c908decf9d595751bc527382e43 469 SMART SM00345 9 66 3.4E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS09020 0c964c908decf9d595751bc527382e43 469 Pfam PF00155 Aminotransferase class I and II 104 452 9.6E-16 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CFK41_RS09020 0c964c908decf9d595751bc527382e43 469 Gene3D G3DSA:3.90.1150.10 372 469 3.9E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS09020 0c964c908decf9d595751bc527382e43 469 SUPERFAMILY SSF53383 60 466 1.38E-68 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS09020 0c964c908decf9d595751bc527382e43 469 SUPERFAMILY SSF46785 6 74 5.78E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS09020 0c964c908decf9d595751bc527382e43 469 Gene3D G3DSA:3.40.640.10 124 371 1.5E-31 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS09020 0c964c908decf9d595751bc527382e43 469 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 66 2.6E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS09020 0c964c908decf9d595751bc527382e43 469 Gene3D G3DSA:1.10.10.10 2 68 2.0E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS13160 7407ba45b2296611e8b734af720c2b8c 336 Pfam PF01841 Transglutaminase-like superfamily 176 280 1.6E-19 T 28-03-2018 IPR002931 Transglutaminase-like CFK41_RS13160 7407ba45b2296611e8b734af720c2b8c 336 SUPERFAMILY SSF54001 139 307 4.49E-38 T 28-03-2018 CFK41_RS13160 7407ba45b2296611e8b734af720c2b8c 336 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 34 112 1.8E-19 T 28-03-2018 IPR013589 Bacterial transglutaminase-like, N-terminal CFK41_RS13160 7407ba45b2296611e8b734af720c2b8c 336 Gene3D G3DSA:3.90.260.10 187 294 1.8E-7 T 28-03-2018 IPR002931 Transglutaminase-like CFK41_RS13160 7407ba45b2296611e8b734af720c2b8c 336 SMART SM00460 205 282 2.3E-16 T 28-03-2018 IPR002931 Transglutaminase-like CFK41_RS05620 36d19e4eeff0767e586de1d70aa1fae0 272 SUPERFAMILY SSF161098 4 272 3.14E-73 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS05620 36d19e4eeff0767e586de1d70aa1fae0 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 266 1.7E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS05620 36d19e4eeff0767e586de1d70aa1fae0 272 Gene3D G3DSA:1.10.3720.10 2 260 8.4E-46 T 28-03-2018 CFK41_RS11710 69e1d7ee8668dc479897de362bcde1dd 752 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 279 354 9.0E-17 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CFK41_RS11710 69e1d7ee8668dc479897de362bcde1dd 752 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 20 732 9.9E-250 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CFK41_RS11710 69e1d7ee8668dc479897de362bcde1dd 752 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 12 737 26.383 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CFK41_RS11710 69e1d7ee8668dc479897de362bcde1dd 752 TIGRFAM TIGR02696 pppGpp_PNP: guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase 7 732 0.0 T 28-03-2018 IPR014069 Guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase GO:0004654|GO:0005737|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CFK41_RS11710 69e1d7ee8668dc479897de362bcde1dd 752 Gene3D G3DSA:3.30.1370.10 588 655 1.8E-13 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CFK41_RS11710 69e1d7ee8668dc479897de362bcde1dd 752 Pfam PF00013 KH domain 596 653 2.3E-11 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CFK41_RS11710 69e1d7ee8668dc479897de362bcde1dd 752 Pfam PF01138 3' exoribonuclease family, domain 1 359 491 7.4E-15 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CFK41_RS11710 69e1d7ee8668dc479897de362bcde1dd 752 Pfam PF01138 3' exoribonuclease family, domain 1 22 154 1.4E-12 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CFK41_RS11710 69e1d7ee8668dc479897de362bcde1dd 752 Pfam PF00575 S1 RNA binding domain 659 733 5.7E-13 T 28-03-2018 IPR003029 S1 domain GO:0003676 CFK41_RS11710 69e1d7ee8668dc479897de362bcde1dd 752 SUPERFAMILY SSF54791 593 679 1.42E-18 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CFK41_RS11710 69e1d7ee8668dc479897de362bcde1dd 752 SUPERFAMILY SSF46915 272 356 7.85E-15 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CFK41_RS11710 69e1d7ee8668dc479897de362bcde1dd 752 PIRSF PIRSF005499 10 752 5.4E-272 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CFK41_RS11710 69e1d7ee8668dc479897de362bcde1dd 752 SMART SM00322 590 658 1.0E-11 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CFK41_RS11710 69e1d7ee8668dc479897de362bcde1dd 752 SUPERFAMILY SSF50249 657 731 2.07E-14 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS11710 69e1d7ee8668dc479897de362bcde1dd 752 SUPERFAMILY SSF55666 155 268 1.78E-21 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CFK41_RS11710 69e1d7ee8668dc479897de362bcde1dd 752 Gene3D G3DSA:3.30.230.70 20 266 1.1E-34 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CFK41_RS11710 69e1d7ee8668dc479897de362bcde1dd 752 Gene3D G3DSA:3.30.230.70 347 587 2.3E-49 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CFK41_RS11710 69e1d7ee8668dc479897de362bcde1dd 752 Gene3D G3DSA:1.10.10.400 271 346 6.1E-20 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CFK41_RS11710 69e1d7ee8668dc479897de362bcde1dd 752 SUPERFAMILY SSF55666 485 584 5.0E-23 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CFK41_RS11710 69e1d7ee8668dc479897de362bcde1dd 752 Gene3D G3DSA:2.40.50.140 656 739 1.3E-17 T 28-03-2018 CFK41_RS11710 69e1d7ee8668dc479897de362bcde1dd 752 SUPERFAMILY SSF54211 331 503 5.57E-42 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CFK41_RS11710 69e1d7ee8668dc479897de362bcde1dd 752 SMART SM00316 660 734 2.1E-16 T 28-03-2018 IPR022967 RNA-binding domain, S1 CFK41_RS11710 69e1d7ee8668dc479897de362bcde1dd 752 SUPERFAMILY SSF54211 11 154 1.52E-41 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CFK41_RS03335 7be25591305765f145ffb48ab891f24f 583 Pfam PF13641 Glycosyltransferase like family 2 102 348 9.5E-28 T 28-03-2018 CFK41_RS03335 7be25591305765f145ffb48ab891f24f 583 Gene3D G3DSA:3.90.550.10 72 373 3.4E-18 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS03335 7be25591305765f145ffb48ab891f24f 583 SUPERFAMILY SSF53448 101 350 1.22E-22 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS08475 a97d3fdad24bf45e1599eb08dd65b4e8 445 Pfam PF00120 Glutamine synthetase, catalytic domain 105 439 1.2E-117 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CFK41_RS08475 a97d3fdad24bf45e1599eb08dd65b4e8 445 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 98 1.1E-23 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CFK41_RS08475 a97d3fdad24bf45e1599eb08dd65b4e8 445 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 232 247 - T 28-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CFK41_RS08475 a97d3fdad24bf45e1599eb08dd65b4e8 445 SUPERFAMILY SSF54368 5 102 6.93E-25 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CFK41_RS08475 a97d3fdad24bf45e1599eb08dd65b4e8 445 SMART SM01230 104 355 1.1E-118 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CFK41_RS08475 a97d3fdad24bf45e1599eb08dd65b4e8 445 Gene3D G3DSA:3.10.20.70 3 103 4.4E-29 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CFK41_RS08475 a97d3fdad24bf45e1599eb08dd65b4e8 445 Gene3D G3DSA:3.30.590.10 104 445 8.2E-113 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CFK41_RS08475 a97d3fdad24bf45e1599eb08dd65b4e8 445 SUPERFAMILY SSF55931 105 443 3.92E-112 T 28-03-2018 CFK41_RS09485 7ea9683d64c2f873a8900386457d412f 128 Gene3D G3DSA:2.120.10.30 8 114 4.0E-4 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CFK41_RS09485 7ea9683d64c2f873a8900386457d412f 128 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 62 111 1.0E-19 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CFK41_RS09485 7ea9683d64c2f873a8900386457d412f 128 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 39 111 3.0E-32 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CFK41_RS09485 7ea9683d64c2f873a8900386457d412f 128 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 13 116 29.936 T 28-03-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CFK41_RS09485 7ea9683d64c2f873a8900386457d412f 128 SUPERFAMILY SSF141734 13 114 1.44E-44 T 28-03-2018 CFK41_RS11855 9d0d1e43dfb1fb995acdb17721bc1da2 356 Gene3D G3DSA:1.10.443.10 117 350 3.3E-44 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CFK41_RS11855 9d0d1e43dfb1fb995acdb17721bc1da2 356 SUPERFAMILY SSF56349 177 354 1.71E-48 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CFK41_RS11855 9d0d1e43dfb1fb995acdb17721bc1da2 356 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 11 356 51.688 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD CFK41_RS11855 9d0d1e43dfb1fb995acdb17721bc1da2 356 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 13 94 1.1E-14 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CFK41_RS11855 9d0d1e43dfb1fb995acdb17721bc1da2 356 Pfam PF00589 Phage integrase family 185 342 4.3E-41 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CFK41_RS11855 9d0d1e43dfb1fb995acdb17721bc1da2 356 Gene3D G3DSA:1.10.150.130 9 116 2.4E-20 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CFK41_RS11855 9d0d1e43dfb1fb995acdb17721bc1da2 356 SUPERFAMILY SSF47823 9 101 1.06E-11 T 28-03-2018 IPR010998 Integrase, Lambda-type, N-terminal CFK41_RS01380 53a21799b624ecf2b18873650ffab5f3 502 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 22 269 3.5E-24 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CFK41_RS01380 53a21799b624ecf2b18873650ffab5f3 502 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 280 474 2.1E-26 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CFK41_RS01380 53a21799b624ecf2b18873650ffab5f3 502 SUPERFAMILY SSF53067 21 271 9.62E-37 T 28-03-2018 CFK41_RS01380 53a21799b624ecf2b18873650ffab5f3 502 Gene3D G3DSA:3.30.420.40 20 261 3.7E-43 T 28-03-2018 CFK41_RS01380 53a21799b624ecf2b18873650ffab5f3 502 Gene3D G3DSA:3.30.420.40 262 500 2.5E-40 T 28-03-2018 CFK41_RS01380 53a21799b624ecf2b18873650ffab5f3 502 SUPERFAMILY SSF53067 279 490 2.45E-29 T 28-03-2018 CFK41_RS05140 864e12c9ab906bcdde39a49b0c4f07c3 109 SUPERFAMILY SSF69118 9 103 5.89E-22 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CFK41_RS05140 864e12c9ab906bcdde39a49b0c4f07c3 109 Gene3D G3DSA:1.20.1290.10 5 109 7.5E-22 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CFK41_RS05140 864e12c9ab906bcdde39a49b0c4f07c3 109 Pfam PF02627 Carboxymuconolactone decarboxylase family 19 103 1.7E-20 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CFK41_RS05140 864e12c9ab906bcdde39a49b0c4f07c3 109 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 38 88 1.5E-15 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CFK41_RS17450 04b82dcb05ba08fd55647eaa49cf6ac0 204 SUPERFAMILY SSF63380 1 87 8.42E-24 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CFK41_RS17450 04b82dcb05ba08fd55647eaa49cf6ac0 204 Gene3D G3DSA:2.40.30.20 1 88 2.1E-27 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS17450 04b82dcb05ba08fd55647eaa49cf6ac0 204 Gene3D G3DSA:2.40.30.20 93 190 1.1E-35 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS17450 04b82dcb05ba08fd55647eaa49cf6ac0 204 PIRSF PIRSF000498 1 203 6.1E-69 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CFK41_RS17450 04b82dcb05ba08fd55647eaa49cf6ac0 204 SUPERFAMILY SSF63380 92 194 3.49E-32 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CFK41_RS17450 04b82dcb05ba08fd55647eaa49cf6ac0 204 Pfam PF00677 Lumazine binding domain 99 183 1.6E-24 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CFK41_RS17450 04b82dcb05ba08fd55647eaa49cf6ac0 204 Pfam PF00677 Lumazine binding domain 3 85 3.2E-21 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CFK41_RS17450 04b82dcb05ba08fd55647eaa49cf6ac0 204 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 192 1.8E-64 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CFK41_RS07830 555c9fea141c822b6e1e9da8f8951d65 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 279 3.1E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS07830 555c9fea141c822b6e1e9da8f8951d65 285 Gene3D G3DSA:1.10.3720.10 1 284 8.5E-38 T 28-03-2018 CFK41_RS07830 555c9fea141c822b6e1e9da8f8951d65 285 SUPERFAMILY SSF161098 41 271 4.06E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS04490 a65f5f826fca6441ed73662353269274 143 SUPERFAMILY SSF54747 4 74 8.37E-29 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CFK41_RS04490 a65f5f826fca6441ed73662353269274 143 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 5 142 1.2E-62 T 28-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04490 a65f5f826fca6441ed73662353269274 143 Pfam PF03946 Ribosomal protein L11, N-terminal domain 11 68 3.9E-28 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CFK41_RS04490 a65f5f826fca6441ed73662353269274 143 Gene3D G3DSA:1.10.10.250 74 142 7.3E-25 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CFK41_RS04490 a65f5f826fca6441ed73662353269274 143 SUPERFAMILY SSF46906 69 142 1.16E-27 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CFK41_RS04490 a65f5f826fca6441ed73662353269274 143 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 7 143 31.186 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CFK41_RS04490 a65f5f826fca6441ed73662353269274 143 Gene3D G3DSA:3.30.1550.10 5 73 6.1E-35 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CFK41_RS04490 a65f5f826fca6441ed73662353269274 143 Pfam PF00298 Ribosomal protein L11, RNA binding domain 73 141 2.6E-26 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CFK41_RS04490 a65f5f826fca6441ed73662353269274 143 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 38 75 9.0E-13 T 28-03-2018 CFK41_RS04490 a65f5f826fca6441ed73662353269274 143 ProSitePatterns PS00359 Ribosomal protein L11 signature. 128 143 - T 28-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04490 a65f5f826fca6441ed73662353269274 143 SMART SM00649 11 142 1.6E-84 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CFK41_RS16095 66ef316117dda1971f0896955430ec50 323 SUPERFAMILY SSF51679 35 250 6.06E-33 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CFK41_RS16095 66ef316117dda1971f0896955430ec50 323 Pfam PF00296 Luciferase-like monooxygenase 36 270 1.1E-15 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CFK41_RS16095 66ef316117dda1971f0896955430ec50 323 Gene3D G3DSA:3.20.20.30 30 322 8.5E-27 T 28-03-2018 CFK41_RS17405 a5d735864fe027d8cd0440addc317d06 463 Pfam PF03441 FAD binding domain of DNA photolyase 281 430 6.9E-66 T 28-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CFK41_RS17405 a5d735864fe027d8cd0440addc317d06 463 Pfam PF00875 DNA photolyase 4 161 2.5E-44 T 28-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CFK41_RS17405 a5d735864fe027d8cd0440addc317d06 463 Gene3D G3DSA:1.25.40.80 126 298 3.4E-39 T 28-03-2018 CFK41_RS17405 a5d735864fe027d8cd0440addc317d06 463 Gene3D G3DSA:3.40.50.620 1 124 3.6E-28 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS17405 a5d735864fe027d8cd0440addc317d06 463 SUPERFAMILY SSF52425 3 172 1.31E-46 T 28-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CFK41_RS17405 a5d735864fe027d8cd0440addc317d06 463 SUPERFAMILY SSF48173 204 459 1.7E-94 T 28-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CFK41_RS17405 a5d735864fe027d8cd0440addc317d06 463 Gene3D G3DSA:1.10.579.10 299 460 6.0E-69 T 28-03-2018 CFK41_RS17405 a5d735864fe027d8cd0440addc317d06 463 PRINTS PR00147 DNA photolyase signature 350 368 3.0E-17 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CFK41_RS17405 a5d735864fe027d8cd0440addc317d06 463 PRINTS PR00147 DNA photolyase signature 330 346 3.0E-17 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CFK41_RS17405 a5d735864fe027d8cd0440addc317d06 463 PRINTS PR00147 DNA photolyase signature 137 153 3.0E-17 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CFK41_RS17405 a5d735864fe027d8cd0440addc317d06 463 PRINTS PR00147 DNA photolyase signature 389 403 3.0E-17 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CFK41_RS01200 380e63b8af83a48935f51f215f3b1b7b 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 1.6E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS01200 380e63b8af83a48935f51f215f3b1b7b 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 1.6E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS01200 380e63b8af83a48935f51f215f3b1b7b 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 1.6E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS01200 380e63b8af83a48935f51f215f3b1b7b 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 1.6E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS01200 380e63b8af83a48935f51f215f3b1b7b 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 1.6E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS01200 380e63b8af83a48935f51f215f3b1b7b 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 1.6E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS01200 380e63b8af83a48935f51f215f3b1b7b 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 259 1.2E-67 T 28-03-2018 CFK41_RS01200 380e63b8af83a48935f51f215f3b1b7b 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CFK41_RS01200 380e63b8af83a48935f51f215f3b1b7b 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 2.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS01200 380e63b8af83a48935f51f215f3b1b7b 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 2.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS01200 380e63b8af83a48935f51f215f3b1b7b 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 2.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS01200 380e63b8af83a48935f51f215f3b1b7b 261 SUPERFAMILY SSF51735 5 260 1.45E-79 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS01200 380e63b8af83a48935f51f215f3b1b7b 261 Gene3D G3DSA:3.40.50.10090 7 55 1.4E-9 T 28-03-2018 CFK41_RS01200 380e63b8af83a48935f51f215f3b1b7b 261 Gene3D G3DSA:3.40.50.720 56 261 2.2E-62 T 28-03-2018 CFK41_RS14565 e29229bb6a2afe2d32616b622db0fe63 145 Pfam PF00583 Acetyltransferase (GNAT) family 39 123 4.0E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS14565 e29229bb6a2afe2d32616b622db0fe63 145 SUPERFAMILY SSF55729 13 137 1.44E-17 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS14565 e29229bb6a2afe2d32616b622db0fe63 145 Gene3D G3DSA:3.40.630.30 9 144 2.4E-16 T 28-03-2018 CFK41_RS07775 95491598497f14fdad189d6e6922434b 583 Pfam PF01964 Radical SAM ThiC family 118 538 1.1E-198 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CFK41_RS07775 95491598497f14fdad189d6e6922434b 583 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 117 544 55.493 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CFK41_RS07775 95491598497f14fdad189d6e6922434b 583 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 117 541 2.2E-207 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CFK41_RS07775 95491598497f14fdad189d6e6922434b 583 Pfam PF13667 ThiC-associated domain 18 75 1.1E-8 T 28-03-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CFK41_RS17570 f71f968fb4b4b002e3ba9fa1062d9dc2 186 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 6 186 8.0E-31 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CFK41_RS17570 f71f968fb4b4b002e3ba9fa1062d9dc2 186 Pfam PF00436 Single-strand binding protein family 7 106 1.3E-29 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CFK41_RS17570 f71f968fb4b4b002e3ba9fa1062d9dc2 186 Gene3D G3DSA:2.40.50.140 1 120 1.9E-40 T 28-03-2018 CFK41_RS17570 f71f968fb4b4b002e3ba9fa1062d9dc2 186 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 30.977 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CFK41_RS17570 f71f968fb4b4b002e3ba9fa1062d9dc2 186 SUPERFAMILY SSF50249 6 186 1.13E-45 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS09120 e24a6e837c5abe02fe1fa6611a96df26 858 Pfam PF01757 Acyltransferase family 468 815 3.4E-26 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CFK41_RS08515 bc88dc4298a8f6375fc79430af8a7b94 232 Pfam PF03099 Biotin/lipoate A/B protein ligase family 73 176 8.0E-7 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CFK41_RS08515 bc88dc4298a8f6375fc79430af8a7b94 232 PIRSF PIRSF016262 19 231 1.9E-51 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CFK41_RS08515 bc88dc4298a8f6375fc79430af8a7b94 232 Gene3D G3DSA:3.30.930.10 22 224 1.2E-60 T 28-03-2018 CFK41_RS08515 bc88dc4298a8f6375fc79430af8a7b94 232 SUPERFAMILY SSF55681 25 223 1.16E-55 T 28-03-2018 CFK41_RS08515 bc88dc4298a8f6375fc79430af8a7b94 232 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 50 222 6.3E-32 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CFK41_RS08515 bc88dc4298a8f6375fc79430af8a7b94 232 Hamap MF_00013 Octanoyltransferase [lipB]. 20 226 28.535 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CFK41_RS08515 bc88dc4298a8f6375fc79430af8a7b94 232 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 90 142 3.0E-12 T 28-03-2018 CFK41_RS10305 94e0943f82c148427e88ff42a6074425 267 SUPERFAMILY SSF53474 7 254 7.97E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS10305 94e0943f82c148427e88ff42a6074425 267 Pfam PF12697 Alpha/beta hydrolase family 16 246 3.3E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CFK41_RS10305 94e0943f82c148427e88ff42a6074425 267 Gene3D G3DSA:3.40.50.1820 3 261 4.1E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS10305 94e0943f82c148427e88ff42a6074425 267 PRINTS PR00412 Epoxide hydrolase signature 40 55 1.2E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CFK41_RS10305 94e0943f82c148427e88ff42a6074425 267 PRINTS PR00412 Epoxide hydrolase signature 20 38 1.2E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CFK41_RS10305 94e0943f82c148427e88ff42a6074425 267 PRINTS PR00412 Epoxide hydrolase signature 230 252 1.2E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CFK41_RS10305 94e0943f82c148427e88ff42a6074425 267 PRINTS PR00412 Epoxide hydrolase signature 199 215 1.2E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CFK41_RS07115 cc127b7dd4f3a85c22ef467688778f4b 739 Pfam PF00128 Alpha amylase, catalytic domain 203 293 3.0E-6 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CFK41_RS07115 cc127b7dd4f3a85c22ef467688778f4b 739 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 19 710 5.4E-223 T 28-03-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 CFK41_RS07115 cc127b7dd4f3a85c22ef467688778f4b 739 SUPERFAMILY SSF81296 24 161 7.47E-23 T 28-03-2018 IPR014756 Immunoglobulin E-set CFK41_RS07115 cc127b7dd4f3a85c22ef467688778f4b 739 SUPERFAMILY SSF51011 632 732 1.22E-9 T 28-03-2018 CFK41_RS07115 cc127b7dd4f3a85c22ef467688778f4b 739 Gene3D G3DSA:2.60.40.1180 622 735 1.5E-17 T 28-03-2018 CFK41_RS07115 cc127b7dd4f3a85c22ef467688778f4b 739 SUPERFAMILY SSF51445 147 507 2.24E-118 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS07115 cc127b7dd4f3a85c22ef467688778f4b 739 SUPERFAMILY SSF51445 541 616 2.24E-118 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS07115 cc127b7dd4f3a85c22ef467688778f4b 739 Gene3D G3DSA:2.60.40.10 12 153 5.8E-22 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS07115 cc127b7dd4f3a85c22ef467688778f4b 739 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 19 103 2.1E-5 T 28-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 CFK41_RS07115 cc127b7dd4f3a85c22ef467688778f4b 739 SMART SM00642 180 599 5.6E-6 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CFK41_RS07115 cc127b7dd4f3a85c22ef467688778f4b 739 Gene3D G3DSA:3.20.20.80 154 621 3.6E-97 T 28-03-2018 CFK41_RS04240 69c859a9b1b2109d04929f1c74682057 679 Pfam PF00326 Prolyl oligopeptidase family 457 667 3.1E-33 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CFK41_RS04240 69c859a9b1b2109d04929f1c74682057 679 Pfam PF07676 WD40-like Beta Propeller Repeat 75 116 0.0087 T 28-03-2018 IPR011659 WD40-like Beta Propeller CFK41_RS04240 69c859a9b1b2109d04929f1c74682057 679 Gene3D G3DSA:2.130.10.150 33 189 3.6E-7 T 28-03-2018 CFK41_RS04240 69c859a9b1b2109d04929f1c74682057 679 SUPERFAMILY SSF53474 416 667 1.99E-51 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS04240 69c859a9b1b2109d04929f1c74682057 679 Gene3D G3DSA:2.140.10.30 190 387 1.9E-16 T 28-03-2018 CFK41_RS04240 69c859a9b1b2109d04929f1c74682057 679 SUPERFAMILY SSF69304 37 154 4.84E-20 T 28-03-2018 CFK41_RS04240 69c859a9b1b2109d04929f1c74682057 679 SUPERFAMILY SSF69304 242 378 4.84E-20 T 28-03-2018 CFK41_RS04240 69c859a9b1b2109d04929f1c74682057 679 Gene3D G3DSA:3.40.50.1820 388 673 1.5E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS10295 7b86c511d242739f06bb7ac269628ed0 157 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 6 156 33.026 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CFK41_RS10295 7b86c511d242739f06bb7ac269628ed0 157 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 8 151 3.1E-52 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CFK41_RS10295 7b86c511d242739f06bb7ac269628ed0 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 10 28 6.2E-40 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CFK41_RS10295 7b86c511d242739f06bb7ac269628ed0 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 33 51 6.2E-40 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CFK41_RS10295 7b86c511d242739f06bb7ac269628ed0 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 54 72 6.2E-40 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CFK41_RS10295 7b86c511d242739f06bb7ac269628ed0 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 119 138 6.2E-40 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CFK41_RS10295 7b86c511d242739f06bb7ac269628ed0 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 78 96 6.2E-40 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CFK41_RS10295 7b86c511d242739f06bb7ac269628ed0 157 Gene3D G3DSA:3.30.1360.80 8 155 1.6E-55 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CFK41_RS10295 7b86c511d242739f06bb7ac269628ed0 157 PIRSF PIRSF006160 6 157 8.6E-57 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CFK41_RS10295 7b86c511d242739f06bb7ac269628ed0 157 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 13 145 6.0E-43 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CFK41_RS10295 7b86c511d242739f06bb7ac269628ed0 157 SUPERFAMILY SSF63411 7 153 7.23E-56 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CFK41_RS05020 0d05ebb02a659b9be5d20ee5fb8ccaa8 415 Gene3D G3DSA:3.90.1510.10 48 285 1.7E-80 T 28-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 CFK41_RS05020 0d05ebb02a659b9be5d20ee5fb8ccaa8 415 SUPERFAMILY SSF110738 9 384 5.75E-113 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CFK41_RS05020 0d05ebb02a659b9be5d20ee5fb8ccaa8 415 Pfam PF02595 Glycerate kinase family 9 382 1.6E-127 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CFK41_RS05020 0d05ebb02a659b9be5d20ee5fb8ccaa8 415 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 9 383 2.0E-132 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CFK41_RS05020 0d05ebb02a659b9be5d20ee5fb8ccaa8 415 PIRSF PIRSF006078 7 386 1.8E-107 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CFK41_RS07990 f60af450a0fb36a79e6068fe092b2171 600 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 9 528 9.4E-136 T 28-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CFK41_RS07990 f60af450a0fb36a79e6068fe092b2171 600 SUPERFAMILY SSF57770 139 173 9.81E-12 T 28-03-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CFK41_RS07990 f60af450a0fb36a79e6068fe092b2171 600 Pfam PF09334 tRNA synthetases class I (M) 7 411 5.6E-142 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS07990 f60af450a0fb36a79e6068fe092b2171 600 Gene3D G3DSA:2.20.28.20 146 162 3.0E-16 T 28-03-2018 CFK41_RS07990 f60af450a0fb36a79e6068fe092b2171 600 SUPERFAMILY SSF52374 7 138 2.1E-89 T 28-03-2018 CFK41_RS07990 f60af450a0fb36a79e6068fe092b2171 600 SUPERFAMILY SSF52374 173 399 2.1E-89 T 28-03-2018 CFK41_RS07990 f60af450a0fb36a79e6068fe092b2171 600 Gene3D G3DSA:3.40.50.620 3 145 3.2E-15 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS07990 f60af450a0fb36a79e6068fe092b2171 600 PRINTS PR01041 Methionyl-tRNA synthetase signature 6 19 7.8E-24 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CFK41_RS07990 f60af450a0fb36a79e6068fe092b2171 600 PRINTS PR01041 Methionyl-tRNA synthetase signature 293 308 7.8E-24 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CFK41_RS07990 f60af450a0fb36a79e6068fe092b2171 600 PRINTS PR01041 Methionyl-tRNA synthetase signature 253 264 7.8E-24 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CFK41_RS07990 f60af450a0fb36a79e6068fe092b2171 600 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 7.8E-24 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CFK41_RS07990 f60af450a0fb36a79e6068fe092b2171 600 PRINTS PR01041 Methionyl-tRNA synthetase signature 399 410 7.8E-24 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CFK41_RS07990 f60af450a0fb36a79e6068fe092b2171 600 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 7.8E-24 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CFK41_RS07990 f60af450a0fb36a79e6068fe092b2171 600 Hamap MF_00098 Methionine--tRNA ligase [metG]. 2 592 36.608 T 28-03-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CFK41_RS07990 f60af450a0fb36a79e6068fe092b2171 600 Gene3D G3DSA:2.170.220.10 163 251 4.3E-19 T 28-03-2018 CFK41_RS07990 f60af450a0fb36a79e6068fe092b2171 600 Gene3D G3DSA:1.10.730.10 388 583 1.4E-35 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS07990 f60af450a0fb36a79e6068fe092b2171 600 SUPERFAMILY SSF47323 562 591 4.86E-27 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS07990 f60af450a0fb36a79e6068fe092b2171 600 SUPERFAMILY SSF47323 404 531 4.86E-27 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS07990 f60af450a0fb36a79e6068fe092b2171 600 Gene3D G3DSA:3.40.50.620 252 387 3.2E-23 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS04075 61631afe01b06c1af0765fc0cbc8566f 124 Pfam PF00857 Isochorismatase family 1 123 1.4E-19 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CFK41_RS04075 61631afe01b06c1af0765fc0cbc8566f 124 SUPERFAMILY SSF52499 1 123 5.23E-24 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CFK41_RS04075 61631afe01b06c1af0765fc0cbc8566f 124 Gene3D G3DSA:3.40.50.850 1 124 1.2E-22 T 28-03-2018 CFK41_RS11120 2138f5a2b9fd974527a0ad3e6bfff713 365 Pfam PF00487 Fatty acid desaturase 68 326 1.0E-41 T 28-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 CFK41_RS11120 2138f5a2b9fd974527a0ad3e6bfff713 365 PIRSF PIRSF015921 5 353 6.0E-73 T 28-03-2018 IPR012171 Fatty acid desaturase GO:0006629|GO:0016021|GO:0016491 CFK41_RS07365 9c19f85aa3c789dd8ac7900beb669e09 439 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 4 435 1.9E-130 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CFK41_RS07365 9c19f85aa3c789dd8ac7900beb669e09 439 SUPERFAMILY SSF55205 4 435 3.6E-112 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CFK41_RS07365 9c19f85aa3c789dd8ac7900beb669e09 439 Gene3D G3DSA:3.65.10.10 22 226 1.8E-37 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CFK41_RS07365 9c19f85aa3c789dd8ac7900beb669e09 439 Gene3D G3DSA:3.65.10.10 227 437 2.3E-44 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CFK41_RS07365 9c19f85aa3c789dd8ac7900beb669e09 439 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 428 2.9E-60 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CFK41_RS07365 9c19f85aa3c789dd8ac7900beb669e09 439 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 2 438 35.281 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CFK41_RS02705 3ed22aaf75619bb21d0cdab871904350 451 Gene3D G3DSA:3.40.50.410 207 408 1.2E-8 T 28-03-2018 IPR002035 von Willebrand factor, type A CFK41_RS02705 3ed22aaf75619bb21d0cdab871904350 451 Pfam PF01882 Protein of unknown function DUF58 202 268 4.0E-16 T 28-03-2018 IPR002881 Domain of unknown function DUF58 CFK41_RS08850 14bc940bc1358c1c2ea30ff50097ae2a 466 Gene3D G3DSA:1.25.40.20 71 305 8.1E-14 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CFK41_RS08850 14bc940bc1358c1c2ea30ff50097ae2a 466 SMART SM00248 104 142 4100.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CFK41_RS08850 14bc940bc1358c1c2ea30ff50097ae2a 466 SMART SM00248 397 426 4.0E-5 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CFK41_RS08850 14bc940bc1358c1c2ea30ff50097ae2a 466 SMART SM00248 239 268 1100.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CFK41_RS08850 14bc940bc1358c1c2ea30ff50097ae2a 466 SMART SM00248 341 371 860.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CFK41_RS08850 14bc940bc1358c1c2ea30ff50097ae2a 466 Pfam PF00023 Ankyrin repeat 398 428 3.2E-4 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CFK41_RS08850 14bc940bc1358c1c2ea30ff50097ae2a 466 SUPERFAMILY SSF48403 244 432 5.74E-18 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CFK41_RS08850 14bc940bc1358c1c2ea30ff50097ae2a 466 Gene3D G3DSA:1.25.40.20 306 458 4.1E-15 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CFK41_RS00950 e716b0334dfec18fdbcde121f5df8416 232 Pfam PF01066 CDP-alcohol phosphatidyltransferase 54 123 2.7E-6 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CFK41_RS00950 e716b0334dfec18fdbcde121f5df8416 232 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 101 123 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CFK41_RS05850 26b099aefdc33206209c640ce6813b8d 2072 Gene3D G3DSA:2.60.120.640 411 510 3.2E-14 T 28-03-2018 CFK41_RS05850 26b099aefdc33206209c640ce6813b8d 2072 SUPERFAMILY SSF49265 1680 1874 1.69E-17 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CFK41_RS05850 26b099aefdc33206209c640ce6813b8d 2072 Gene3D G3DSA:2.60.40.10 600 690 0.068 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS05850 26b099aefdc33206209c640ce6813b8d 2072 SMART SM00060 1774 1858 5.5E-4 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CFK41_RS05850 26b099aefdc33206209c640ce6813b8d 2072 SMART SM00060 1876 2016 5.5 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CFK41_RS05850 26b099aefdc33206209c640ce6813b8d 2072 SMART SM00060 1675 1758 9.7E-4 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CFK41_RS05850 26b099aefdc33206209c640ce6813b8d 2072 SMART SM00060 1579 1659 2.1E-6 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CFK41_RS05850 26b099aefdc33206209c640ce6813b8d 2072 SMART SM00060 1488 1564 2.9E-11 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CFK41_RS05850 26b099aefdc33206209c640ce6813b8d 2072 Gene3D G3DSA:2.60.500.10 698 797 0.013 T 28-03-2018 CFK41_RS05850 26b099aefdc33206209c640ce6813b8d 2072 Gene3D G3DSA:2.60.500.10 801 895 3.2E-7 T 28-03-2018 CFK41_RS05850 26b099aefdc33206209c640ce6813b8d 2072 Gene3D G3DSA:2.60.500.10 995 1090 4.4E-7 T 28-03-2018 CFK41_RS05850 26b099aefdc33206209c640ce6813b8d 2072 Gene3D G3DSA:2.60.500.10 1100 1182 0.0023 T 28-03-2018 CFK41_RS05850 26b099aefdc33206209c640ce6813b8d 2072 Gene3D G3DSA:2.60.500.10 897 994 1.0E-8 T 28-03-2018 CFK41_RS05850 26b099aefdc33206209c640ce6813b8d 2072 Gene3D G3DSA:2.60.500.10 1398 1485 2.3E-5 T 28-03-2018 CFK41_RS05850 26b099aefdc33206209c640ce6813b8d 2072 Gene3D G3DSA:2.60.500.10 1194 1291 7.8E-6 T 28-03-2018 CFK41_RS05850 26b099aefdc33206209c640ce6813b8d 2072 Gene3D G3DSA:2.60.40.10 1882 1953 0.082 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS05850 26b099aefdc33206209c640ce6813b8d 2072 Gene3D G3DSA:2.60.40.10 1772 1881 3.1E-14 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS05850 26b099aefdc33206209c640ce6813b8d 2072 Gene3D G3DSA:2.60.40.10 1581 1677 6.7E-19 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS05850 26b099aefdc33206209c640ce6813b8d 2072 Pfam PF00041 Fibronectin type III domain 1582 1656 1.2E-11 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CFK41_RS05850 26b099aefdc33206209c640ce6813b8d 2072 Pfam PF00041 Fibronectin type III domain 1796 1855 5.9E-7 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CFK41_RS05850 26b099aefdc33206209c640ce6813b8d 2072 Pfam PF00041 Fibronectin type III domain 1490 1567 9.8E-8 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CFK41_RS05850 26b099aefdc33206209c640ce6813b8d 2072 Gene3D G3DSA:2.60.40.10 1678 1771 4.0E-9 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS05850 26b099aefdc33206209c640ce6813b8d 2072 Gene3D G3DSA:2.60.40.10 1999 2039 0.52 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS05850 26b099aefdc33206209c640ce6813b8d 2072 Gene3D G3DSA:2.60.40.10 1294 1389 3.0E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS05850 26b099aefdc33206209c640ce6813b8d 2072 Gene3D G3DSA:2.60.40.10 1486 1580 6.5E-19 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS05850 26b099aefdc33206209c640ce6813b8d 2072 Gene3D G3DSA:2.60.40.10 511 599 2.9E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS05850 26b099aefdc33206209c640ce6813b8d 2072 Gene3D G3DSA:2.60.40.10 1954 1998 0.038 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS05850 26b099aefdc33206209c640ce6813b8d 2072 SUPERFAMILY SSF49265 1487 1669 5.45E-33 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CFK41_RS00825 f0923bd694f925e247db40d4d6b81a8d 440 Gene3D G3DSA:1.20.1530.10 18 415 1.9E-129 T 28-03-2018 IPR023171 Na/H antiporter domain CFK41_RS00825 f0923bd694f925e247db40d4d6b81a8d 440 Pfam PF06965 Na+/H+ antiporter 1 24 409 2.0E-125 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CFK41_RS00825 f0923bd694f925e247db40d4d6b81a8d 440 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 20 419 20.246 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CFK41_RS00825 f0923bd694f925e247db40d4d6b81a8d 440 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 29 408 8.5E-94 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CFK41_RS15380 67aaf002cfaa9552f442518108f78292 402 SUPERFAMILY SSF51905 6 164 4.99E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS15380 67aaf002cfaa9552f442518108f78292 402 SUPERFAMILY SSF51905 194 327 4.99E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS15380 67aaf002cfaa9552f442518108f78292 402 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 143 167 1.8E-8 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CFK41_RS15380 67aaf002cfaa9552f442518108f78292 402 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 1.8E-8 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CFK41_RS15380 67aaf002cfaa9552f442518108f78292 402 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 105 113 1.8E-8 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CFK41_RS15380 67aaf002cfaa9552f442518108f78292 402 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 267 285 1.8E-8 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CFK41_RS15380 67aaf002cfaa9552f442518108f78292 402 Pfam PF14721 Apoptosis-inducing factor, mitochondrion-associated, C-term 304 341 1.4E-6 T 28-03-2018 IPR029324 Mitochondrial apoptosis-inducing factor, C-terminal domain GO:0046983 CFK41_RS15380 67aaf002cfaa9552f442518108f78292 402 SUPERFAMILY SSF55424 317 387 1.19E-15 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CFK41_RS15380 67aaf002cfaa9552f442518108f78292 402 SMART SM01353 304 385 9.5E-4 T 28-03-2018 CFK41_RS15380 67aaf002cfaa9552f442518108f78292 402 Gene3D G3DSA:3.30.390.30 318 391 4.5E-20 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CFK41_RS15380 67aaf002cfaa9552f442518108f78292 402 Gene3D G3DSA:3.50.50.60 127 184 4.5E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS15380 67aaf002cfaa9552f442518108f78292 402 Gene3D G3DSA:3.50.50.60 185 317 6.9E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS15380 67aaf002cfaa9552f442518108f78292 402 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 301 1.3E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS15380 67aaf002cfaa9552f442518108f78292 402 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 2.6E-21 T 28-03-2018 CFK41_RS15380 67aaf002cfaa9552f442518108f78292 402 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 279 2.6E-21 T 28-03-2018 CFK41_RS15380 67aaf002cfaa9552f442518108f78292 402 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 2.6E-21 T 28-03-2018 CFK41_RS15380 67aaf002cfaa9552f442518108f78292 402 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 2.6E-21 T 28-03-2018 CFK41_RS15380 67aaf002cfaa9552f442518108f78292 402 Gene3D G3DSA:3.50.50.60 6 126 4.6E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS07755 4986adb6d3e39a18b0664c7200ec7c74 442 Pfam PF01546 Peptidase family M20/M25/M40 77 378 2.2E-6 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CFK41_RS07755 4986adb6d3e39a18b0664c7200ec7c74 442 SUPERFAMILY SSF53187 4 212 3.66E-32 T 28-03-2018 CFK41_RS07755 4986adb6d3e39a18b0664c7200ec7c74 442 SUPERFAMILY SSF53187 313 395 3.66E-32 T 28-03-2018 CFK41_RS07755 4986adb6d3e39a18b0664c7200ec7c74 442 SUPERFAMILY SSF55031 197 313 2.54E-18 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CFK41_RS07755 4986adb6d3e39a18b0664c7200ec7c74 442 Gene3D G3DSA:3.40.630.10 1 283 3.1E-29 T 28-03-2018 CFK41_RS07755 4986adb6d3e39a18b0664c7200ec7c74 442 Gene3D G3DSA:3.40.630.10 284 401 3.2E-8 T 28-03-2018 CFK41_RS12140 b36f21e5982e27bd03f5052f37624296 446 Pfam PF07724 AAA domain (Cdc48 subfamily) 132 327 1.2E-47 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CFK41_RS12140 b36f21e5982e27bd03f5052f37624296 446 SMART SM00994 10 49 1.5E-19 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CFK41_RS12140 b36f21e5982e27bd03f5052f37624296 446 SMART SM01086 333 419 1.1E-28 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CFK41_RS12140 b36f21e5982e27bd03f5052f37624296 446 Pfam PF06689 ClpX C4-type zinc finger 12 48 2.1E-18 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CFK41_RS12140 b36f21e5982e27bd03f5052f37624296 446 SMART SM00382 131 284 1.0E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS12140 b36f21e5982e27bd03f5052f37624296 446 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 8 427 9.3E-188 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CFK41_RS12140 b36f21e5982e27bd03f5052f37624296 446 SUPERFAMILY SSF52540 63 416 5.24E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS12140 b36f21e5982e27bd03f5052f37624296 446 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 333 411 5.4E-15 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CFK41_RS12140 b36f21e5982e27bd03f5052f37624296 446 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 431 51.172 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CFK41_RS12140 b36f21e5982e27bd03f5052f37624296 446 Gene3D G3DSA:1.10.8.60 333 424 1.6E-30 T 28-03-2018 CFK41_RS12140 b36f21e5982e27bd03f5052f37624296 446 SUPERFAMILY SSF57716 12 46 1.57E-10 T 28-03-2018 CFK41_RS12140 b36f21e5982e27bd03f5052f37624296 446 Gene3D G3DSA:3.40.50.300 55 331 1.7E-68 T 28-03-2018 CFK41_RS16160 2c98e5bf6836731f8b6b3174dee6f202 209 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 71 87 - T 28-03-2018 IPR033693 Pyroglutamyl peptidase I, Glu active site CFK41_RS16160 2c98e5bf6836731f8b6b3174dee6f202 209 Pfam PF01470 Pyroglutamyl peptidase 4 175 9.1E-57 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CFK41_RS16160 2c98e5bf6836731f8b6b3174dee6f202 209 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 82 102 4.7E-32 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CFK41_RS16160 2c98e5bf6836731f8b6b3174dee6f202 209 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 5 28 4.7E-32 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CFK41_RS16160 2c98e5bf6836731f8b6b3174dee6f202 209 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 64 76 4.7E-32 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CFK41_RS16160 2c98e5bf6836731f8b6b3174dee6f202 209 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 134 150 4.7E-32 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CFK41_RS16160 2c98e5bf6836731f8b6b3174dee6f202 209 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 132 146 - T 28-03-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site CFK41_RS16160 2c98e5bf6836731f8b6b3174dee6f202 209 Gene3D G3DSA:3.40.630.20 1 199 6.4E-51 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CFK41_RS16160 2c98e5bf6836731f8b6b3174dee6f202 209 SUPERFAMILY SSF53182 4 206 5.62E-53 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CFK41_RS16160 2c98e5bf6836731f8b6b3174dee6f202 209 PIRSF PIRSF015592 2 204 2.8E-61 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CFK41_RS00790 30331566b8bea70d1fe54a0a266137aa 377 Pfam PF01032 FecCD transport family 93 373 7.7E-41 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CFK41_RS00790 30331566b8bea70d1fe54a0a266137aa 377 Gene3D G3DSA:1.10.3470.10 49 376 1.3E-30 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CFK41_RS00790 30331566b8bea70d1fe54a0a266137aa 377 SUPERFAMILY SSF81345 61 373 4.58E-49 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CFK41_RS03420 39be9bcba041b8091769e9812a12fb95 128 SUPERFAMILY SSF50249 2 66 2.94E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS03420 39be9bcba041b8091769e9812a12fb95 128 Gene3D G3DSA:2.40.50.140 1 84 1.0E-17 T 28-03-2018 CFK41_RS03420 39be9bcba041b8091769e9812a12fb95 128 PRINTS PR00050 Cold shock protein signature 25 34 2.7E-10 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CFK41_RS03420 39be9bcba041b8091769e9812a12fb95 128 PRINTS PR00050 Cold shock protein signature 4 19 2.7E-10 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CFK41_RS03420 39be9bcba041b8091769e9812a12fb95 128 PRINTS PR00050 Cold shock protein signature 39 57 2.7E-10 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CFK41_RS03420 39be9bcba041b8091769e9812a12fb95 128 Pfam PF00313 'Cold-shock' DNA-binding domain 3 59 1.7E-14 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CFK41_RS03420 39be9bcba041b8091769e9812a12fb95 128 SMART SM00357 3 66 2.1E-16 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CFK41_RS11635 0816b7256b2c8006f187e456750948d2 373 Pfam PF00154 recA bacterial DNA recombination protein 23 283 2.3E-142 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CFK41_RS11635 0816b7256b2c8006f187e456750948d2 373 SUPERFAMILY SSF54752 283 340 7.59E-20 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CFK41_RS11635 0816b7256b2c8006f187e456750948d2 373 ProSitePatterns PS00321 recA signature. 228 236 - T 28-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 CFK41_RS11635 0816b7256b2c8006f187e456750948d2 373 Gene3D G3DSA:3.40.50.300 41 283 3.6E-49 T 28-03-2018 CFK41_RS11635 0816b7256b2c8006f187e456750948d2 373 SMART SM00382 72 243 8.6E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS11635 0816b7256b2c8006f187e456750948d2 373 Gene3D G3DSA:3.30.250.10 284 341 4.2E-24 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CFK41_RS11635 0816b7256b2c8006f187e456750948d2 373 SUPERFAMILY SSF52540 21 282 4.21E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11635 0816b7256b2c8006f187e456750948d2 373 PRINTS PR00142 RecA protein signature 180 209 3.2E-84 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CFK41_RS11635 0816b7256b2c8006f187e456750948d2 373 PRINTS PR00142 RecA protein signature 142 171 3.2E-84 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CFK41_RS11635 0816b7256b2c8006f187e456750948d2 373 PRINTS PR00142 RecA protein signature 312 329 3.2E-84 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CFK41_RS11635 0816b7256b2c8006f187e456750948d2 373 PRINTS PR00142 RecA protein signature 108 137 3.2E-84 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CFK41_RS11635 0816b7256b2c8006f187e456750948d2 373 PRINTS PR00142 RecA protein signature 225 253 3.2E-84 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CFK41_RS11635 0816b7256b2c8006f187e456750948d2 373 PRINTS PR00142 RecA protein signature 258 287 3.2E-84 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CFK41_RS11635 0816b7256b2c8006f187e456750948d2 373 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 19 337 1.8E-171 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CFK41_RS11635 0816b7256b2c8006f187e456750948d2 373 Hamap MF_00268 Protein RecA [recA]. 20 344 52.078 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CFK41_RS07680 383d4064d3c221328f1d0033033f302b 400 Gene3D G3DSA:3.60.21.10 52 367 2.8E-27 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CFK41_RS07680 383d4064d3c221328f1d0033033f302b 400 SUPERFAMILY SSF56300 300 362 3.17E-34 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CFK41_RS07680 383d4064d3c221328f1d0033033f302b 400 SUPERFAMILY SSF56300 60 270 3.17E-34 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CFK41_RS07680 383d4064d3c221328f1d0033033f302b 400 Pfam PF00149 Calcineurin-like phosphoesterase 62 319 5.6E-14 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CFK41_RS13050 986e2e150418bed70ce1e68d4136ff9b 558 Gene3D G3DSA:3.40.50.300 295 551 2.8E-67 T 28-03-2018 CFK41_RS13050 986e2e150418bed70ce1e68d4136ff9b 558 Gene3D G3DSA:3.40.50.300 13 294 7.1E-64 T 28-03-2018 CFK41_RS13050 986e2e150418bed70ce1e68d4136ff9b 558 ProSitePatterns PS00211 ABC transporters family signature. 438 452 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS13050 986e2e150418bed70ce1e68d4136ff9b 558 SMART SM00382 323 515 1.3E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS13050 986e2e150418bed70ce1e68d4136ff9b 558 SMART SM00382 41 241 2.3E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS13050 986e2e150418bed70ce1e68d4136ff9b 558 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS13050 986e2e150418bed70ce1e68d4136ff9b 558 Pfam PF00005 ABC transporter 33 192 3.4E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS13050 986e2e150418bed70ce1e68d4136ff9b 558 Pfam PF00005 ABC transporter 314 466 1.8E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS13050 986e2e150418bed70ce1e68d4136ff9b 558 SUPERFAMILY SSF52540 16 263 7.78E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS13050 986e2e150418bed70ce1e68d4136ff9b 558 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 244 277 0.31 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CFK41_RS13050 986e2e150418bed70ce1e68d4136ff9b 558 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 517 549 0.0027 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CFK41_RS13050 986e2e150418bed70ce1e68d4136ff9b 558 SUPERFAMILY SSF52540 296 536 1.01E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS03150 fb472ff14d24bffe0a6cac73a7c6e8cc 342 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 243 259 - T 28-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CFK41_RS03150 fb472ff14d24bffe0a6cac73a7c6e8cc 342 PRINTS PR00151 Porphobilinogen deaminase signature 82 101 1.2E-29 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CFK41_RS03150 fb472ff14d24bffe0a6cac73a7c6e8cc 342 PRINTS PR00151 Porphobilinogen deaminase signature 242 259 1.2E-29 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CFK41_RS03150 fb472ff14d24bffe0a6cac73a7c6e8cc 342 PRINTS PR00151 Porphobilinogen deaminase signature 51 71 1.2E-29 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CFK41_RS03150 fb472ff14d24bffe0a6cac73a7c6e8cc 342 PRINTS PR00151 Porphobilinogen deaminase signature 130 147 1.2E-29 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CFK41_RS03150 fb472ff14d24bffe0a6cac73a7c6e8cc 342 PRINTS PR00151 Porphobilinogen deaminase signature 149 166 1.2E-29 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CFK41_RS03150 fb472ff14d24bffe0a6cac73a7c6e8cc 342 Gene3D G3DSA:3.30.160.40 233 340 1.6E-21 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CFK41_RS03150 fb472ff14d24bffe0a6cac73a7c6e8cc 342 SUPERFAMILY SSF54782 232 340 2.22E-17 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CFK41_RS03150 fb472ff14d24bffe0a6cac73a7c6e8cc 342 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 13 215 5.0E-66 T 28-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CFK41_RS03150 fb472ff14d24bffe0a6cac73a7c6e8cc 342 PIRSF PIRSF001438 3 342 8.5E-106 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CFK41_RS03150 fb472ff14d24bffe0a6cac73a7c6e8cc 342 Gene3D G3DSA:3.40.190.10 7 112 7.5E-36 T 28-03-2018 CFK41_RS03150 fb472ff14d24bffe0a6cac73a7c6e8cc 342 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 12 331 31.496 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CFK41_RS03150 fb472ff14d24bffe0a6cac73a7c6e8cc 342 Gene3D G3DSA:3.40.190.10 113 207 3.6E-33 T 28-03-2018 CFK41_RS03150 fb472ff14d24bffe0a6cac73a7c6e8cc 342 SUPERFAMILY SSF53850 12 215 8.14E-62 T 28-03-2018 CFK41_RS03150 fb472ff14d24bffe0a6cac73a7c6e8cc 342 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 239 328 5.1E-13 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CFK41_RS03150 fb472ff14d24bffe0a6cac73a7c6e8cc 342 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 13 267 8.0E-81 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CFK41_RS06800 632a178401780968c16e78aa4731c0c0 634 SUPERFAMILY SSF48208 223 620 2.38E-105 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CFK41_RS06800 632a178401780968c16e78aa4731c0c0 634 SMART SM00479 12 186 1.1E-22 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CFK41_RS06800 632a178401780968c16e78aa4731c0c0 634 Pfam PF00929 Exonuclease 14 176 1.0E-21 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CFK41_RS06800 632a178401780968c16e78aa4731c0c0 634 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 252 607 1.5E-108 T 28-03-2018 CFK41_RS06800 632a178401780968c16e78aa4731c0c0 634 Gene3D G3DSA:1.50.10.10 221 634 7.3E-86 T 28-03-2018 CFK41_RS06800 632a178401780968c16e78aa4731c0c0 634 SUPERFAMILY SSF53098 10 184 3.34E-40 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CFK41_RS06800 632a178401780968c16e78aa4731c0c0 634 Gene3D G3DSA:3.30.420.10 8 186 6.3E-28 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CFK41_RS07960 040653ff723ac422b4bb69125299d374 283 Pfam PF04954 Siderophore-interacting protein 151 264 3.2E-28 T 28-03-2018 IPR007037 Siderophore-interacting protein CFK41_RS07960 040653ff723ac422b4bb69125299d374 283 SUPERFAMILY SSF63380 23 148 7.29E-7 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CFK41_RS07960 040653ff723ac422b4bb69125299d374 283 Pfam PF08021 Siderophore-interacting FAD-binding domain 26 141 5.4E-27 T 28-03-2018 IPR013113 FAD-binding 9, siderophore-interacting CFK41_RS07960 040653ff723ac422b4bb69125299d374 283 Gene3D G3DSA:3.40.50.80 144 283 2.7E-36 T 28-03-2018 CFK41_RS07960 040653ff723ac422b4bb69125299d374 283 Gene3D G3DSA:2.40.30.10 15 142 2.0E-25 T 28-03-2018 CFK41_RS00700 c99c76fa006e3088ed083c6f5872e7e5 463 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 4 322 2.8E-109 T 28-03-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 CFK41_RS00700 c99c76fa006e3088ed083c6f5872e7e5 463 Pfam PF03741 Integral membrane protein TerC family 69 275 4.2E-48 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CFK41_RS04910 83e295a4a2acc3d2237e844047650097 622 Pfam PF13522 Glutamine amidotransferase domain 71 192 2.6E-19 T 28-03-2018 CFK41_RS04910 83e295a4a2acc3d2237e844047650097 622 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 622 38.897 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CFK41_RS04910 83e295a4a2acc3d2237e844047650097 622 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 622 1.9E-232 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CFK41_RS04910 83e295a4a2acc3d2237e844047650097 622 SUPERFAMILY SSF56235 2 239 2.4E-62 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CFK41_RS04910 83e295a4a2acc3d2237e844047650097 622 Gene3D G3DSA:3.40.50.10490 250 467 2.2E-66 T 28-03-2018 CFK41_RS04910 83e295a4a2acc3d2237e844047650097 622 Gene3D G3DSA:3.40.50.10490 468 620 4.9E-47 T 28-03-2018 CFK41_RS04910 83e295a4a2acc3d2237e844047650097 622 Pfam PF01380 SIS domain 299 424 2.4E-32 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CFK41_RS04910 83e295a4a2acc3d2237e844047650097 622 Pfam PF01380 SIS domain 473 603 2.4E-22 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CFK41_RS04910 83e295a4a2acc3d2237e844047650097 622 Gene3D G3DSA:3.60.20.10 2 249 1.3E-65 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CFK41_RS04910 83e295a4a2acc3d2237e844047650097 622 SUPERFAMILY SSF53697 255 622 1.39E-106 T 28-03-2018 CFK41_RS01330 efd663b8948d6dc7a043fef1dbc1478c 362 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 259 323 3.0E-19 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CFK41_RS01330 efd663b8948d6dc7a043fef1dbc1478c 362 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 257 336 2.3E-25 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CFK41_RS01330 efd663b8948d6dc7a043fef1dbc1478c 362 ProSitePatterns PS00211 ABC transporters family signature. 180 194 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS01330 efd663b8948d6dc7a043fef1dbc1478c 362 SMART SM00382 52 257 3.3E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS01330 efd663b8948d6dc7a043fef1dbc1478c 362 Pfam PF00005 ABC transporter 43 207 2.4E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS01330 efd663b8948d6dc7a043fef1dbc1478c 362 SUPERFAMILY SSF52540 10 285 4.63E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS01330 efd663b8948d6dc7a043fef1dbc1478c 362 Gene3D G3DSA:3.40.50.300 19 361 1.8E-73 T 28-03-2018 CFK41_RS14000 fdd24b27743e490fcd8d51e8ba83a642 447 Pfam PF07075 Protein of unknown function (DUF1343) 77 447 5.2E-129 T 28-03-2018 IPR008302 Uncharacterised conserved protein UCP016719 CFK41_RS14000 fdd24b27743e490fcd8d51e8ba83a642 447 PIRSF PIRSF016719 30 447 8.1E-137 T 28-03-2018 IPR008302 Uncharacterised conserved protein UCP016719 CFK41_RS01355 242e8aeef4427212c420453ed9c38d0c 762 Gene3D G3DSA:1.50.10.10 323 678 2.7E-50 T 28-03-2018 CFK41_RS01355 242e8aeef4427212c420453ed9c38d0c 762 SUPERFAMILY SSF48208 321 748 6.8E-48 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CFK41_RS01355 242e8aeef4427212c420453ed9c38d0c 762 Gene3D G3DSA:2.60.420.10 679 758 3.0E-25 T 28-03-2018 CFK41_RS01355 242e8aeef4427212c420453ed9c38d0c 762 Gene3D G3DSA:2.60.120.260 17 201 5.2E-36 T 28-03-2018 IPR008979 Galactose-binding domain-like CFK41_RS01355 242e8aeef4427212c420453ed9c38d0c 762 Gene3D G3DSA:2.60.120.260 203 322 4.1E-41 T 28-03-2018 IPR008979 Galactose-binding domain-like CFK41_RS01355 242e8aeef4427212c420453ed9c38d0c 762 Pfam PF17390 Bacterial alpha-L-rhamnosidase C-terminal domain 685 753 8.2E-20 T 28-03-2018 IPR035398 Alpha-L-rhamnosidase C-terminal domain CFK41_RS01355 242e8aeef4427212c420453ed9c38d0c 762 Pfam PF08531 Alpha-L-rhamnosidase N-terminal domain 50 182 3.9E-37 T 28-03-2018 IPR013737 Bacterial alpha-L-rhamnosidase N-terminal CFK41_RS01355 242e8aeef4427212c420453ed9c38d0c 762 Pfam PF17389 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain 324 683 7.0E-106 T 28-03-2018 IPR035396 Alpha-L-rhamnosidase, six-hairpin glycosidase domain CFK41_RS01355 242e8aeef4427212c420453ed9c38d0c 762 Pfam PF05592 Bacterial alpha-L-rhamnosidase concanavalin-like domain 222 320 5.3E-31 T 28-03-2018 IPR008902 Alpha-L-rhamnosidase, concanavalin-like domain CFK41_RS05060 fb5f55e71d74004d0a49f56b90f462dd 361 SUPERFAMILY SSF81271 277 358 1.44E-33 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CFK41_RS05060 fb5f55e71d74004d0a49f56b90f462dd 361 Gene3D G3DSA:1.10.150.300 110 200 3.0E-20 T 28-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 CFK41_RS05060 fb5f55e71d74004d0a49f56b90f462dd 361 Gene3D G3DSA:3.10.20.30 261 360 1.4E-42 T 28-03-2018 IPR012675 Beta-grasp domain CFK41_RS05060 fb5f55e71d74004d0a49f56b90f462dd 361 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 361 40.454 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CFK41_RS05060 fb5f55e71d74004d0a49f56b90f462dd 361 Pfam PF01926 50S ribosome-binding GTPase 5 115 2.6E-22 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CFK41_RS05060 fb5f55e71d74004d0a49f56b90f462dd 361 SUPERFAMILY SSF52540 3 299 1.76E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS05060 fb5f55e71d74004d0a49f56b90f462dd 361 PIRSF PIRSF006641 1 361 7.2E-135 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CFK41_RS05060 fb5f55e71d74004d0a49f56b90f462dd 361 Gene3D G3DSA:1.20.120.430 2 90 3.6E-9 T 28-03-2018 CFK41_RS05060 fb5f55e71d74004d0a49f56b90f462dd 361 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 3 360 2.5E-125 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CFK41_RS05060 fb5f55e71d74004d0a49f56b90f462dd 361 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.2E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CFK41_RS05060 fb5f55e71d74004d0a49f56b90f462dd 361 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 1.2E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CFK41_RS05060 fb5f55e71d74004d0a49f56b90f462dd 361 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 1.2E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CFK41_RS05060 fb5f55e71d74004d0a49f56b90f462dd 361 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 1.2E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CFK41_RS05060 fb5f55e71d74004d0a49f56b90f462dd 361 Pfam PF06071 Protein of unknown function (DUF933) 277 359 2.3E-36 T 28-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 CFK41_RS14135 bb868918aeaeae7f0484b904f0d64ce5 247 Pfam PF01872 RibD C-terminal domain 30 238 5.1E-26 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CFK41_RS14135 bb868918aeaeae7f0484b904f0d64ce5 247 SUPERFAMILY SSF53597 30 244 4.36E-36 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CFK41_RS14135 bb868918aeaeae7f0484b904f0d64ce5 247 Gene3D G3DSA:3.40.430.10 23 247 2.2E-46 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CFK41_RS02305 b083531c399cec04fffad3e7e86ca9a5 452 SUPERFAMILY SSF55031 301 338 1.4E-11 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CFK41_RS02305 b083531c399cec04fffad3e7e86ca9a5 452 SUPERFAMILY SSF55031 215 259 1.4E-11 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CFK41_RS02305 b083531c399cec04fffad3e7e86ca9a5 452 SUPERFAMILY SSF53187 9 199 3.28E-52 T 28-03-2018 CFK41_RS02305 b083531c399cec04fffad3e7e86ca9a5 452 SUPERFAMILY SSF53187 362 451 3.28E-52 T 28-03-2018 CFK41_RS02305 b083531c399cec04fffad3e7e86ca9a5 452 Gene3D G3DSA:3.30.70.360 219 363 8.8E-24 T 28-03-2018 CFK41_RS02305 b083531c399cec04fffad3e7e86ca9a5 452 Gene3D G3DSA:3.40.630.10 8 218 1.7E-43 T 28-03-2018 CFK41_RS02305 b083531c399cec04fffad3e7e86ca9a5 452 Pfam PF01546 Peptidase family M20/M25/M40 91 450 1.4E-31 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CFK41_RS02305 b083531c399cec04fffad3e7e86ca9a5 452 Pfam PF07687 Peptidase dimerisation domain 212 334 6.0E-16 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CFK41_RS04895 630b09d17d248e0569278be45b85218c 1107 Gene3D G3DSA:3.40.50.10810 646 860 4.8E-44 T 28-03-2018 CFK41_RS04895 630b09d17d248e0569278be45b85218c 1107 SUPERFAMILY SSF52540 602 859 3.12E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS04895 630b09d17d248e0569278be45b85218c 1107 SMART SM00490 972 1052 2.4E-21 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS04895 630b09d17d248e0569278be45b85218c 1107 SUPERFAMILY SSF52540 860 1106 5.99E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS04895 630b09d17d248e0569278be45b85218c 1107 Pfam PF00271 Helicase conserved C-terminal domain 951 1052 5.1E-14 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS04895 630b09d17d248e0569278be45b85218c 1107 Gene3D G3DSA:3.40.50.300 932 1090 9.6E-35 T 28-03-2018 CFK41_RS04895 630b09d17d248e0569278be45b85218c 1107 SMART SM00487 641 837 6.7E-23 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CFK41_RS04895 630b09d17d248e0569278be45b85218c 1107 Pfam PF00176 SNF2 family N-terminal domain 659 900 9.1E-49 T 28-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 CFK41_RS10115 e801c95a3afd591c23b4f07cdfa8bc51 314 SUPERFAMILY SSF111331 4 307 6.15E-72 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CFK41_RS10115 e801c95a3afd591c23b4f07cdfa8bc51 314 Gene3D G3DSA:3.40.50.10330 2 154 6.1E-30 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CFK41_RS10115 e801c95a3afd591c23b4f07cdfa8bc51 314 Gene3D G3DSA:2.60.200.30 155 278 2.4E-34 T 28-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CFK41_RS10115 e801c95a3afd591c23b4f07cdfa8bc51 314 Pfam PF01513 ATP-NAD kinase 65 285 1.6E-56 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CFK41_RS10115 e801c95a3afd591c23b4f07cdfa8bc51 314 Hamap MF_00361 NAD kinase [nadK]. 2 301 29.731 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CFK41_RS05150 34a929c66c6e7776ed6096bb42b7b5e7 133 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 3.7E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS05150 34a929c66c6e7776ed6096bb42b7b5e7 133 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 3.7E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS05150 34a929c66c6e7776ed6096bb42b7b5e7 133 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 3.7E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS05150 34a929c66c6e7776ed6096bb42b7b5e7 133 Gene3D G3DSA:1.10.1660.10 56 133 2.0E-8 T 28-03-2018 CFK41_RS05150 34a929c66c6e7776ed6096bb42b7b5e7 133 SMART SM00422 1 69 2.2E-20 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS05150 34a929c66c6e7776ed6096bb42b7b5e7 133 Pfam PF13411 MerR HTH family regulatory protein 1 66 6.8E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS05150 34a929c66c6e7776ed6096bb42b7b5e7 133 SUPERFAMILY SSF46955 1 119 4.76E-26 T 28-03-2018 IPR009061 Putative DNA-binding domain CFK41_RS05150 34a929c66c6e7776ed6096bb42b7b5e7 133 Gene3D G3DSA:1.10.1660.10 1 55 3.1E-19 T 28-03-2018 CFK41_RS12310 3328c92a0b96326240d7e0c25a72ea45 175 Gene3D G3DSA:3.30.1330.50 1 166 2.9E-55 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CFK41_RS12310 3328c92a0b96326240d7e0c25a72ea45 175 SUPERFAMILY SSF69765 10 164 1.57E-47 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CFK41_RS12310 3328c92a0b96326240d7e0c25a72ea45 175 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 10 165 29.568 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CFK41_RS12310 3328c92a0b96326240d7e0c25a72ea45 175 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 11 164 8.8E-41 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CFK41_RS12310 3328c92a0b96326240d7e0c25a72ea45 175 Pfam PF02542 YgbB family 11 163 3.2E-43 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CFK41_RS12310 3328c92a0b96326240d7e0c25a72ea45 175 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 47 62 - T 28-03-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CFK41_RS00800 6bfd3c767c18724cedf43e5d60a2e9f1 282 Gene3D G3DSA:3.20.20.100 1 280 7.9E-95 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS00800 6bfd3c767c18724cedf43e5d60a2e9f1 282 SUPERFAMILY SSF51430 13 271 5.37E-94 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS00800 6bfd3c767c18724cedf43e5d60a2e9f1 282 PRINTS PR00069 Aldo-keto reductase signature 41 65 2.3E-46 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS00800 6bfd3c767c18724cedf43e5d60a2e9f1 282 PRINTS PR00069 Aldo-keto reductase signature 202 226 2.3E-46 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS00800 6bfd3c767c18724cedf43e5d60a2e9f1 282 PRINTS PR00069 Aldo-keto reductase signature 97 115 2.3E-46 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS00800 6bfd3c767c18724cedf43e5d60a2e9f1 282 PRINTS PR00069 Aldo-keto reductase signature 129 146 2.3E-46 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS00800 6bfd3c767c18724cedf43e5d60a2e9f1 282 PRINTS PR00069 Aldo-keto reductase signature 163 192 2.3E-46 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS00800 6bfd3c767c18724cedf43e5d60a2e9f1 282 Pfam PF00248 Aldo/keto reductase family 28 267 8.9E-54 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS00800 6bfd3c767c18724cedf43e5d60a2e9f1 282 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 45 62 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CFK41_RS00800 6bfd3c767c18724cedf43e5d60a2e9f1 282 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 129 146 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CFK41_RS00800 6bfd3c767c18724cedf43e5d60a2e9f1 282 PIRSF PIRSF000097 5 273 3.0E-83 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS00800 6bfd3c767c18724cedf43e5d60a2e9f1 282 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 235 250 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CFK41_RS01425 c088bd594f19d80d6f8a0bd70fee3025 333 Pfam PF13377 Periplasmic binding protein-like domain 174 332 4.4E-28 T 28-03-2018 CFK41_RS01425 c088bd594f19d80d6f8a0bd70fee3025 333 ProSitePatterns PS00356 LacI-type HTH domain signature. 13 31 - T 28-03-2018 CFK41_RS01425 c088bd594f19d80d6f8a0bd70fee3025 333 SMART SM00354 10 80 6.3E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS01425 c088bd594f19d80d6f8a0bd70fee3025 333 Gene3D G3DSA:1.10.260.40 12 66 2.6E-18 T 28-03-2018 CFK41_RS01425 c088bd594f19d80d6f8a0bd70fee3025 333 SUPERFAMILY SSF47413 10 68 4.5E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS01425 c088bd594f19d80d6f8a0bd70fee3025 333 Gene3D G3DSA:3.40.50.2300 67 179 6.2E-21 T 28-03-2018 CFK41_RS01425 c088bd594f19d80d6f8a0bd70fee3025 333 Gene3D G3DSA:3.40.50.2300 180 333 1.0E-33 T 28-03-2018 CFK41_RS01425 c088bd594f19d80d6f8a0bd70fee3025 333 SUPERFAMILY SSF53822 70 332 1.2E-47 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS01425 c088bd594f19d80d6f8a0bd70fee3025 333 Pfam PF00356 Bacterial regulatory proteins, lacI family 13 55 2.8E-13 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS16140 d4ae22a83b5d1cc3fbb4a9d35562bec4 608 Gene3D G3DSA:1.20.1560.10 1 323 7.3E-52 T 28-03-2018 CFK41_RS16140 d4ae22a83b5d1cc3fbb4a9d35562bec4 608 ProSitePatterns PS00211 ABC transporters family signature. 483 497 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS16140 d4ae22a83b5d1cc3fbb4a9d35562bec4 608 Pfam PF00005 ABC transporter 359 510 1.9E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS16140 d4ae22a83b5d1cc3fbb4a9d35562bec4 608 SUPERFAMILY SSF52540 332 579 5.43E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS16140 d4ae22a83b5d1cc3fbb4a9d35562bec4 608 SUPERFAMILY SSF90123 6 317 9.55E-59 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS16140 d4ae22a83b5d1cc3fbb4a9d35562bec4 608 Pfam PF00664 ABC transporter transmembrane region 20 290 1.3E-37 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS16140 d4ae22a83b5d1cc3fbb4a9d35562bec4 608 Gene3D G3DSA:3.40.50.300 324 587 1.0E-66 T 28-03-2018 CFK41_RS16140 d4ae22a83b5d1cc3fbb4a9d35562bec4 608 SMART SM00382 367 557 3.9E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS08550 7e0f0c06bb85f6e591eca7b4593d72ad 367 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 320 340 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CFK41_RS08550 7e0f0c06bb85f6e591eca7b4593d72ad 367 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 99 118 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CFK41_RS08550 7e0f0c06bb85f6e591eca7b4593d72ad 367 Pfam PF01180 Dihydroorotate dehydrogenase 67 365 8.8E-89 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CFK41_RS08550 7e0f0c06bb85f6e591eca7b4593d72ad 367 SUPERFAMILY SSF51395 13 365 1.89E-95 T 28-03-2018 CFK41_RS08550 7e0f0c06bb85f6e591eca7b4593d72ad 367 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 12 364 43.367 T 28-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CFK41_RS08550 7e0f0c06bb85f6e591eca7b4593d72ad 367 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 15 364 5.0E-118 T 28-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CFK41_RS08550 7e0f0c06bb85f6e591eca7b4593d72ad 367 Gene3D G3DSA:3.20.20.70 9 367 7.9E-81 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS14725 26ea361fcb0c70533ab570f5d086ada5 311 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 256 269 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CFK41_RS14725 26ea361fcb0c70533ab570f5d086ada5 311 Gene3D G3DSA:3.40.1190.20 8 309 2.2E-67 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS14725 26ea361fcb0c70533ab570f5d086ada5 311 SUPERFAMILY SSF53613 11 307 3.74E-67 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS14725 26ea361fcb0c70533ab570f5d086ada5 311 PRINTS PR00990 Ribokinase signature 181 196 2.2E-28 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CFK41_RS14725 26ea361fcb0c70533ab570f5d086ada5 311 PRINTS PR00990 Ribokinase signature 113 126 2.2E-28 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CFK41_RS14725 26ea361fcb0c70533ab570f5d086ada5 311 PRINTS PR00990 Ribokinase signature 227 238 2.2E-28 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CFK41_RS14725 26ea361fcb0c70533ab570f5d086ada5 311 PRINTS PR00990 Ribokinase signature 41 60 2.2E-28 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CFK41_RS14725 26ea361fcb0c70533ab570f5d086ada5 311 PRINTS PR00990 Ribokinase signature 14 35 2.2E-28 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CFK41_RS14725 26ea361fcb0c70533ab570f5d086ada5 311 Hamap MF_01987 Ribokinase [rbsK]. 10 311 22.602 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CFK41_RS14725 26ea361fcb0c70533ab570f5d086ada5 311 Pfam PF00294 pfkB family carbohydrate kinase 11 303 7.6E-56 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CFK41_RS07495 2dfaed6b777e4507e7e9d2f641360cb1 557 ProSitePatterns PS00211 ABC transporters family signature. 477 491 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS07495 2dfaed6b777e4507e7e9d2f641360cb1 557 Pfam PF00664 ABC transporter transmembrane region 27 288 2.0E-7 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS07495 2dfaed6b777e4507e7e9d2f641360cb1 557 SUPERFAMILY SSF90123 22 321 1.96E-32 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS07495 2dfaed6b777e4507e7e9d2f641360cb1 557 Gene3D G3DSA:1.20.1560.10 8 321 1.8E-22 T 28-03-2018 CFK41_RS07495 2dfaed6b777e4507e7e9d2f641360cb1 557 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 12 540 7.3E-147 T 28-03-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 CFK41_RS07495 2dfaed6b777e4507e7e9d2f641360cb1 557 Pfam PF00005 ABC transporter 359 504 5.2E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS07495 2dfaed6b777e4507e7e9d2f641360cb1 557 SUPERFAMILY SSF52540 349 555 1.87E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS07495 2dfaed6b777e4507e7e9d2f641360cb1 557 Gene3D G3DSA:3.40.50.300 333 557 2.6E-48 T 28-03-2018 CFK41_RS07495 2dfaed6b777e4507e7e9d2f641360cb1 557 SMART SM00382 365 557 1.6E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS05185 bafacb44d3b403c52fbbc98a788ec85c 233 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 1 195 1.1E-45 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CFK41_RS05185 bafacb44d3b403c52fbbc98a788ec85c 233 TIGRFAM TIGR03848 MSMEG_4193: probable phosphomutase, MSMEG_4193 family 1 202 1.1E-90 T 28-03-2018 IPR022492 Phosphomutase MSMEG4193, putative CFK41_RS05185 bafacb44d3b403c52fbbc98a788ec85c 233 SUPERFAMILY SSF53254 1 197 1.28E-41 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CFK41_RS05185 bafacb44d3b403c52fbbc98a788ec85c 233 Gene3D G3DSA:3.40.50.1240 1 200 7.6E-39 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CFK41_RS05185 bafacb44d3b403c52fbbc98a788ec85c 233 SMART SM00855 1 157 7.9E-14 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CFK41_RS07015 59be4d38dbc6ae292c9efbdea9435c2c 301 SUPERFAMILY SSF53335 45 285 1.09E-44 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS07015 59be4d38dbc6ae292c9efbdea9435c2c 301 Gene3D G3DSA:1.10.8.10 8 90 6.6E-14 T 28-03-2018 CFK41_RS07015 59be4d38dbc6ae292c9efbdea9435c2c 301 Gene3D G3DSA:3.40.50.150 91 288 4.2E-39 T 28-03-2018 CFK41_RS07015 59be4d38dbc6ae292c9efbdea9435c2c 301 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 50 286 2.5E-42 T 28-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 CFK41_RS07015 59be4d38dbc6ae292c9efbdea9435c2c 301 Pfam PF05175 Methyltransferase small domain 90 197 3.4E-13 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CFK41_RS07015 59be4d38dbc6ae292c9efbdea9435c2c 301 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 190 196 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CFK41_RS08500 9a571391dcee78afaff88e8203b4908d 144 Pfam PF06271 RDD family 63 120 5.5E-7 T 28-03-2018 IPR010432 RDD CFK41_RS14400 c8ccf228dc77e7fe6520027a2dc0dc29 378 SUPERFAMILY SSF103473 44 364 3.53E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS14400 c8ccf228dc77e7fe6520027a2dc0dc29 378 Gene3D G3DSA:1.20.1250.20 10 159 1.3E-14 T 28-03-2018 CFK41_RS14400 c8ccf228dc77e7fe6520027a2dc0dc29 378 Gene3D G3DSA:1.20.1250.20 173 367 2.0E-28 T 28-03-2018 CFK41_RS14400 c8ccf228dc77e7fe6520027a2dc0dc29 378 Pfam PF07690 Major Facilitator Superfamily 33 315 4.2E-32 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS07480 5ffc4289456eb030e0d0c64fe2014260 113 Gene3D G3DSA:1.20.1290.10 1 113 1.2E-30 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CFK41_RS07480 5ffc4289456eb030e0d0c64fe2014260 113 SUPERFAMILY SSF69118 7 111 4.71E-29 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CFK41_RS07480 5ffc4289456eb030e0d0c64fe2014260 113 Pfam PF02627 Carboxymuconolactone decarboxylase family 25 107 6.5E-21 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CFK41_RS07790 2fd0e22ff48a7a888f295f497e96cef6 430 Gene3D G3DSA:3.40.190.10 58 184 6.2E-18 T 28-03-2018 CFK41_RS07790 2fd0e22ff48a7a888f295f497e96cef6 430 Pfam PF13416 Bacterial extracellular solute-binding protein 83 372 3.5E-43 T 28-03-2018 CFK41_RS07790 2fd0e22ff48a7a888f295f497e96cef6 430 SUPERFAMILY SSF53850 64 427 3.05E-72 T 28-03-2018 CFK41_RS07790 2fd0e22ff48a7a888f295f497e96cef6 430 Gene3D G3DSA:3.40.190.10 185 418 6.5E-42 T 28-03-2018 CFK41_RS08085 b1b7f8191c2a68b9b52b4b561735470a 550 PIRSF PIRSF005522 6 485 1.5E-193 T 28-03-2018 IPR016450 Uncharacterised conserved protein UCP005522 CFK41_RS08085 b1b7f8191c2a68b9b52b4b561735470a 550 SUPERFAMILY SSF56059 28 219 6.77E-54 T 28-03-2018 CFK41_RS08085 b1b7f8191c2a68b9b52b4b561735470a 550 SUPERFAMILY SSF56059 327 472 6.77E-54 T 28-03-2018 CFK41_RS08085 b1b7f8191c2a68b9b52b4b561735470a 550 Pfam PF14403 Circularly permuted ATP-grasp type 2 81 458 1.1E-154 T 28-03-2018 IPR025841 Circularly permuted ATP-grasp type 2 CFK41_RS08085 b1b7f8191c2a68b9b52b4b561735470a 550 Gene3D G3DSA:3.30.470.20 344 525 8.9E-11 T 28-03-2018 CFK41_RS12575 acaab6141e7c3afd8177220f0493b735 236 SUPERFAMILY SSF53098 6 206 4.49E-41 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CFK41_RS12575 acaab6141e7c3afd8177220f0493b735 236 Pfam PF00929 Exonuclease 13 183 1.9E-15 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CFK41_RS12575 acaab6141e7c3afd8177220f0493b735 236 SMART SM00479 10 193 8.3E-17 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CFK41_RS12575 acaab6141e7c3afd8177220f0493b735 236 Gene3D G3DSA:3.30.420.10 9 204 1.6E-30 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CFK41_RS05775 4c10e3973133742ee9d9a0eda28e9f9c 373 Gene3D G3DSA:1.10.3720.10 31 360 4.7E-36 T 28-03-2018 CFK41_RS05775 4c10e3973133742ee9d9a0eda28e9f9c 373 SUPERFAMILY SSF161098 139 356 1.09E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS05775 4c10e3973133742ee9d9a0eda28e9f9c 373 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 163 370 1.9E-39 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS08860 ba046c7b67b4a8d342642606ac0b57fa 141 Pfam PF01814 Hemerythrin HHE cation binding domain 1 123 2.2E-18 T 28-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 CFK41_RS08860 ba046c7b67b4a8d342642606ac0b57fa 141 Gene3D G3DSA:1.20.120.520 1 139 2.4E-22 T 28-03-2018 CFK41_RS09730 c60efb130a5a16fe0fdb552e20a29a66 291 Gene3D G3DSA:2.70.98.10 1 291 1.4E-49 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CFK41_RS09730 c60efb130a5a16fe0fdb552e20a29a66 291 Pfam PF01263 Aldose 1-epimerase 29 287 9.1E-28 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 CFK41_RS09730 c60efb130a5a16fe0fdb552e20a29a66 291 PIRSF PIRSF016020 3 290 4.4E-41 T 28-03-2018 IPR025532 Glucose-6-phosphate 1-epimerase KEGG: 00010+5.1.3.15 CFK41_RS09730 c60efb130a5a16fe0fdb552e20a29a66 291 SUPERFAMILY SSF74650 17 287 2.2E-50 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CFK41_RS05480 3f3b38c498fb26c871f191aa6d09a603 1074 SUPERFAMILY SSF48208 430 762 8.84E-13 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CFK41_RS05480 3f3b38c498fb26c871f191aa6d09a603 1074 SUPERFAMILY SSF48208 789 920 8.84E-13 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CFK41_RS05480 3f3b38c498fb26c871f191aa6d09a603 1074 Gene3D G3DSA:3.30.2080.10 795 941 1.9E-42 T 28-03-2018 CFK41_RS05480 3f3b38c498fb26c871f191aa6d09a603 1074 Pfam PF07971 Glycosyl hydrolase family 92 403 922 3.0E-115 T 28-03-2018 IPR012939 Glycosyl hydrolase family 92 CFK41_RS05480 3f3b38c498fb26c871f191aa6d09a603 1074 Gene3D G3DSA:2.60.120.260 965 1072 3.7E-7 T 28-03-2018 IPR008979 Galactose-binding domain-like CFK41_RS05480 3f3b38c498fb26c871f191aa6d09a603 1074 Gene3D G3DSA:1.20.1050.60 527 621 1.4E-21 T 28-03-2018 CFK41_RS05480 3f3b38c498fb26c871f191aa6d09a603 1074 Gene3D G3DSA:2.70.98.10 186 487 2.1E-56 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CFK41_RS05480 3f3b38c498fb26c871f191aa6d09a603 1074 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 405 929 3.9E-96 T 28-03-2018 IPR005887 Alpha-1,2-mannosidase, putative CFK41_RS05480 3f3b38c498fb26c871f191aa6d09a603 1074 Gene3D G3DSA:1.20.1610.10 622 794 6.3E-43 T 28-03-2018 CFK41_RS14835 baa1f95c7d9b0bd8fed804bbe441505f 311 SUPERFAMILY SSF51430 2 305 2.36E-71 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS14835 baa1f95c7d9b0bd8fed804bbe441505f 311 Gene3D G3DSA:3.20.20.100 1 309 9.2E-70 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS14835 baa1f95c7d9b0bd8fed804bbe441505f 311 Pfam PF00248 Aldo/keto reductase family 16 302 4.0E-54 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS00515 38ce2fa94d1b9410cf8c35d6a1af6a48 1171 Gene3D G3DSA:3.30.750.44 780 846 4.4E-14 T 28-03-2018 CFK41_RS00515 38ce2fa94d1b9410cf8c35d6a1af6a48 1171 PIRSF PIRSF036421 1 615 6.4E-106 T 28-03-2018 IPR012393 Tricorn protease GO:0008236 CFK41_RS00515 38ce2fa94d1b9410cf8c35d6a1af6a48 1171 PIRSF PIRSF036421 619 1161 4.0E-167 T 28-03-2018 IPR012393 Tricorn protease GO:0008236 CFK41_RS00515 38ce2fa94d1b9410cf8c35d6a1af6a48 1171 SMART SM00245 936 1128 2.9E-12 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CFK41_RS00515 38ce2fa94d1b9410cf8c35d6a1af6a48 1171 Pfam PF14685 Tricorn protease PDZ domain 858 942 2.3E-22 T 28-03-2018 IPR029414 Tricorn protease, PDZ domain CFK41_RS00515 38ce2fa94d1b9410cf8c35d6a1af6a48 1171 Pfam PF07676 WD40-like Beta Propeller Repeat 490 501 0.07 T 28-03-2018 IPR011659 WD40-like Beta Propeller CFK41_RS00515 38ce2fa94d1b9410cf8c35d6a1af6a48 1171 Pfam PF07676 WD40-like Beta Propeller Repeat 524 546 0.29 T 28-03-2018 IPR011659 WD40-like Beta Propeller CFK41_RS00515 38ce2fa94d1b9410cf8c35d6a1af6a48 1171 Pfam PF07676 WD40-like Beta Propeller Repeat 42 75 2.1E-5 T 28-03-2018 IPR011659 WD40-like Beta Propeller CFK41_RS00515 38ce2fa94d1b9410cf8c35d6a1af6a48 1171 SUPERFAMILY SSF82171 473 558 8.24E-17 T 28-03-2018 CFK41_RS00515 38ce2fa94d1b9410cf8c35d6a1af6a48 1171 SUPERFAMILY SSF82171 387 439 8.24E-17 T 28-03-2018 CFK41_RS00515 38ce2fa94d1b9410cf8c35d6a1af6a48 1171 SUPERFAMILY SSF82171 715 738 8.24E-17 T 28-03-2018 CFK41_RS00515 38ce2fa94d1b9410cf8c35d6a1af6a48 1171 Gene3D G3DSA:3.90.226.10 950 1159 1.5E-28 T 28-03-2018 CFK41_RS00515 38ce2fa94d1b9410cf8c35d6a1af6a48 1171 SUPERFAMILY SSF52096 779 855 6.96E-58 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CFK41_RS00515 38ce2fa94d1b9410cf8c35d6a1af6a48 1171 SUPERFAMILY SSF52096 945 1153 6.96E-58 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CFK41_RS00515 38ce2fa94d1b9410cf8c35d6a1af6a48 1171 SUPERFAMILY SSF69304 12 285 1.7E-31 T 28-03-2018 CFK41_RS00515 38ce2fa94d1b9410cf8c35d6a1af6a48 1171 SUPERFAMILY SSF50156 858 946 2.64E-13 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CFK41_RS00515 38ce2fa94d1b9410cf8c35d6a1af6a48 1171 Gene3D G3DSA:2.30.42.10 857 949 8.4E-7 T 28-03-2018 CFK41_RS00515 38ce2fa94d1b9410cf8c35d6a1af6a48 1171 Pfam PF14684 Tricorn protease C1 domain 780 847 2.9E-22 T 28-03-2018 IPR028204 Tricorn protease C1 domain CFK41_RS00515 38ce2fa94d1b9410cf8c35d6a1af6a48 1171 Gene3D G3DSA:2.130.10.10 264 764 8.4E-46 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CFK41_RS00515 38ce2fa94d1b9410cf8c35d6a1af6a48 1171 Pfam PF03572 Peptidase family S41 973 1127 5.2E-21 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CFK41_RS00515 38ce2fa94d1b9410cf8c35d6a1af6a48 1171 Gene3D G3DSA:2.130.10.10 18 225 6.6E-19 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CFK41_RS16850 c808722fec718c07858fc2fc394cc299 372 Pfam PF00294 pfkB family carbohydrate kinase 59 309 3.3E-28 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CFK41_RS16850 c808722fec718c07858fc2fc394cc299 372 SUPERFAMILY SSF53613 27 320 6.7E-50 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS16850 c808722fec718c07858fc2fc394cc299 372 Gene3D G3DSA:3.40.1190.20 27 328 4.3E-51 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS16430 7f8bc870176020936023e326b49cde4e 324 SUPERFAMILY SSF161098 87 308 8.9E-51 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS16430 7f8bc870176020936023e326b49cde4e 324 Gene3D G3DSA:1.10.3720.10 37 322 9.5E-40 T 28-03-2018 CFK41_RS16430 7f8bc870176020936023e326b49cde4e 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 318 7.5E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01640 80b8e963a28dbf7c186312b35f6ad450 316 Gene3D G3DSA:1.10.3720.10 84 314 9.0E-45 T 28-03-2018 CFK41_RS01640 80b8e963a28dbf7c186312b35f6ad450 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 307 3.8E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01640 80b8e963a28dbf7c186312b35f6ad450 316 SUPERFAMILY SSF161098 77 302 5.1E-63 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01640 80b8e963a28dbf7c186312b35f6ad450 316 Gene3D G3DSA:1.20.58.370 22 66 1.9E-7 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CFK41_RS02950 67ef587345b435c6979b91a8f66a8fed 115 SUPERFAMILY SSF46785 6 99 4.26E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS02950 67ef587345b435c6979b91a8f66a8fed 115 Gene3D G3DSA:1.10.10.10 4 107 4.5E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS02950 67ef587345b435c6979b91a8f66a8fed 115 Pfam PF01022 Bacterial regulatory protein, arsR family 27 73 9.0E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS02950 67ef587345b435c6979b91a8f66a8fed 115 SMART SM00418 20 98 1.8E-26 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS02950 67ef587345b435c6979b91a8f66a8fed 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 2.8E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS02950 67ef587345b435c6979b91a8f66a8fed 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 2.8E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS02950 67ef587345b435c6979b91a8f66a8fed 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 22 37 2.8E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS05915 2081da0061a936871e3b4adf3b11c73c 84 Gene3D G3DSA:1.10.287.850 1 84 2.8E-8 T 28-03-2018 CFK41_RS11400 a8a5f6ce9175d2e077ff8aae0bb34799 486 SUPERFAMILY SSF103473 32 482 1.31E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS11400 a8a5f6ce9175d2e077ff8aae0bb34799 486 Gene3D G3DSA:1.20.1250.20 261 483 2.0E-15 T 28-03-2018 CFK41_RS11400 a8a5f6ce9175d2e077ff8aae0bb34799 486 Gene3D G3DSA:1.20.1250.20 42 258 3.7E-24 T 28-03-2018 CFK41_RS11400 a8a5f6ce9175d2e077ff8aae0bb34799 486 ProSitePatterns PS00216 Sugar transport proteins signature 1. 352 369 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CFK41_RS11400 a8a5f6ce9175d2e077ff8aae0bb34799 486 Pfam PF07690 Major Facilitator Superfamily 68 438 1.2E-23 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS08480 1385f8f71286dc1ce23359dde1ec9f42 1041 Gene3D G3DSA:3.30.460.10 689 879 6.0E-42 T 28-03-2018 CFK41_RS08480 1385f8f71286dc1ce23359dde1ec9f42 1041 Gene3D G3DSA:3.30.460.10 182 350 9.5E-52 T 28-03-2018 CFK41_RS08480 1385f8f71286dc1ce23359dde1ec9f42 1041 SUPERFAMILY SSF81301 757 876 6.54E-50 T 28-03-2018 CFK41_RS08480 1385f8f71286dc1ce23359dde1ec9f42 1041 SUPERFAMILY SSF81301 578 723 6.54E-50 T 28-03-2018 CFK41_RS08480 1385f8f71286dc1ce23359dde1ec9f42 1041 Pfam PF08335 GlnD PII-uridylyltransferase 894 1035 2.8E-20 T 28-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 CFK41_RS08480 1385f8f71286dc1ce23359dde1ec9f42 1041 Pfam PF08335 GlnD PII-uridylyltransferase 363 501 2.9E-37 T 28-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 CFK41_RS08480 1385f8f71286dc1ce23359dde1ec9f42 1041 Gene3D G3DSA:1.20.120.330 883 1039 4.1E-39 T 28-03-2018 CFK41_RS08480 1385f8f71286dc1ce23359dde1ec9f42 1041 Gene3D G3DSA:1.20.120.330 352 505 1.1E-49 T 28-03-2018 CFK41_RS08480 1385f8f71286dc1ce23359dde1ec9f42 1041 SUPERFAMILY SSF81593 357 502 5.18E-38 T 28-03-2018 CFK41_RS08480 1385f8f71286dc1ce23359dde1ec9f42 1041 SUPERFAMILY SSF81593 886 1036 7.77E-32 T 28-03-2018 CFK41_RS08480 1385f8f71286dc1ce23359dde1ec9f42 1041 Gene3D G3DSA:1.10.4050.10 581 687 1.3E-16 T 28-03-2018 CFK41_RS08480 1385f8f71286dc1ce23359dde1ec9f42 1041 Gene3D G3DSA:1.10.4050.10 56 176 8.3E-22 T 28-03-2018 CFK41_RS08480 1385f8f71286dc1ce23359dde1ec9f42 1041 SUPERFAMILY SSF81301 78 350 3.6E-55 T 28-03-2018 CFK41_RS08480 1385f8f71286dc1ce23359dde1ec9f42 1041 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 88 342 5.5E-42 T 28-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 CFK41_RS08480 1385f8f71286dc1ce23359dde1ec9f42 1041 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 606 718 5.6E-13 T 28-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 CFK41_RS08480 1385f8f71286dc1ce23359dde1ec9f42 1041 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 757 868 4.7E-27 T 28-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 CFK41_RS04925 97538534da2ee34c47ca904ea6591b22 389 SUPERFAMILY SSF50621 244 388 1.12E-38 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CFK41_RS04925 97538534da2ee34c47ca904ea6591b22 389 Gene3D G3DSA:2.40.37.10 227 389 6.0E-55 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CFK41_RS04925 97538534da2ee34c47ca904ea6591b22 389 Pfam PF01168 Alanine racemase, N-terminal domain 19 241 1.2E-57 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CFK41_RS04925 97538534da2ee34c47ca904ea6591b22 389 TIGRFAM TIGR00492 alr: alanine racemase 17 387 5.1E-84 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CFK41_RS04925 97538534da2ee34c47ca904ea6591b22 389 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 43 53 - T 28-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CFK41_RS04925 97538534da2ee34c47ca904ea6591b22 389 Pfam PF00842 Alanine racemase, C-terminal domain 252 387 3.0E-37 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CFK41_RS04925 97538534da2ee34c47ca904ea6591b22 389 Gene3D G3DSA:3.20.20.10 22 226 1.5E-39 T 28-03-2018 IPR029066 PLP-binding barrel CFK41_RS04925 97538534da2ee34c47ca904ea6591b22 389 Hamap MF_01201 Alanine racemase. 12 389 30.217 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CFK41_RS04925 97538534da2ee34c47ca904ea6591b22 389 PRINTS PR00992 Alanine racemase signature 215 242 2.3E-39 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CFK41_RS04925 97538534da2ee34c47ca904ea6591b22 389 PRINTS PR00992 Alanine racemase signature 268 283 2.3E-39 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CFK41_RS04925 97538534da2ee34c47ca904ea6591b22 389 PRINTS PR00992 Alanine racemase signature 74 92 2.3E-39 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CFK41_RS04925 97538534da2ee34c47ca904ea6591b22 389 PRINTS PR00992 Alanine racemase signature 172 183 2.3E-39 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CFK41_RS04925 97538534da2ee34c47ca904ea6591b22 389 PRINTS PR00992 Alanine racemase signature 138 150 2.3E-39 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CFK41_RS04925 97538534da2ee34c47ca904ea6591b22 389 PRINTS PR00992 Alanine racemase signature 38 54 2.3E-39 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CFK41_RS04925 97538534da2ee34c47ca904ea6591b22 389 PRINTS PR00992 Alanine racemase signature 285 300 2.3E-39 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CFK41_RS04925 97538534da2ee34c47ca904ea6591b22 389 SMART SM01005 252 389 8.9E-50 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CFK41_RS04925 97538534da2ee34c47ca904ea6591b22 389 SUPERFAMILY SSF51419 19 253 2.88E-54 T 28-03-2018 IPR029066 PLP-binding barrel CFK41_RS10500 94f96e52f395739de7357b10c9f11918 188 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 4 186 40.599 T 28-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CFK41_RS10500 94f96e52f395739de7357b10c9f11918 188 SUPERFAMILY SSF55620 3 186 3.63E-75 T 28-03-2018 CFK41_RS10500 94f96e52f395739de7357b10c9f11918 188 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 113 123 - T 28-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CFK41_RS10500 94f96e52f395739de7357b10c9f11918 188 Gene3D G3DSA:3.30.1130.10 55 188 4.8E-57 T 28-03-2018 CFK41_RS10500 94f96e52f395739de7357b10c9f11918 188 Pfam PF01227 GTP cyclohydrolase I 8 185 3.7E-75 T 28-03-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CFK41_RS10500 94f96e52f395739de7357b10c9f11918 188 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 8 185 7.2E-72 T 28-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CFK41_RS10500 94f96e52f395739de7357b10c9f11918 188 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 64 80 - T 28-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CFK41_RS10500 94f96e52f395739de7357b10c9f11918 188 Gene3D G3DSA:1.10.286.10 6 54 2.8E-23 T 28-03-2018 CFK41_RS07075 bef7726ba49cdf9b6a8f558ed7342118 152 Pfam PF10739 Protein of unknown function (DUF2550) 20 145 1.5E-28 T 28-03-2018 IPR019675 Protein of unknown function DUF2550 CFK41_RS04470 885bd136f5483d1f62c2b1cb6d9e9ffe 418 SUPERFAMILY SSF53383 24 416 8.64E-112 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS04470 885bd136f5483d1f62c2b1cb6d9e9ffe 418 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 257 270 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CFK41_RS04470 885bd136f5483d1f62c2b1cb6d9e9ffe 418 Gene3D G3DSA:3.90.1150.10 297 418 2.1E-29 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS04470 885bd136f5483d1f62c2b1cb6d9e9ffe 418 Gene3D G3DSA:3.40.50.2300 7 79 0.16 T 28-03-2018 CFK41_RS04470 885bd136f5483d1f62c2b1cb6d9e9ffe 418 Gene3D G3DSA:3.40.640.10 80 296 4.5E-56 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS04470 885bd136f5483d1f62c2b1cb6d9e9ffe 418 Pfam PF00155 Aminotransferase class I and II 53 411 1.2E-71 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CFK41_RS04470 885bd136f5483d1f62c2b1cb6d9e9ffe 418 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 137 158 6.6E-11 T 28-03-2018 CFK41_RS04470 885bd136f5483d1f62c2b1cb6d9e9ffe 418 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 220 243 6.6E-11 T 28-03-2018 CFK41_RS04470 885bd136f5483d1f62c2b1cb6d9e9ffe 418 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 184 208 6.6E-11 T 28-03-2018 CFK41_RS04470 885bd136f5483d1f62c2b1cb6d9e9ffe 418 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 251 275 6.6E-11 T 28-03-2018 CFK41_RS00080 9686acb7e15fc87275adfd7ab75b03c3 226 Gene3D G3DSA:1.20.1510.10 17 203 2.3E-17 T 28-03-2018 CFK41_RS00080 9686acb7e15fc87275adfd7ab75b03c3 226 Pfam PF01545 Cation efflux family 32 199 5.9E-11 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CFK41_RS00080 9686acb7e15fc87275adfd7ab75b03c3 226 SUPERFAMILY SSF161111 20 203 1.44E-27 T 28-03-2018 CFK41_RS16840 f36f00ea1c212aced47ee77d23121919 178 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 28 174 1.4E-12 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CFK41_RS16840 f36f00ea1c212aced47ee77d23121919 178 Gene3D G3DSA:3.30.530.20 24 178 3.6E-25 T 28-03-2018 IPR023393 START-like domain CFK41_RS16840 f36f00ea1c212aced47ee77d23121919 178 SUPERFAMILY SSF55961 26 175 1.31E-21 T 28-03-2018 CFK41_RS02525 9688605bb94d656269e22b460cdb3c83 571 SUPERFAMILY SSF55874 388 553 8.25E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS02525 9688605bb94d656269e22b460cdb3c83 571 Pfam PF00512 His Kinase A (phospho-acceptor) domain 332 390 6.9E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CFK41_RS02525 9688605bb94d656269e22b460cdb3c83 571 PRINTS PR00344 Bacterial sensor protein C-terminal signature 480 494 3.0E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS02525 9688605bb94d656269e22b460cdb3c83 571 PRINTS PR00344 Bacterial sensor protein C-terminal signature 515 533 3.0E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS02525 9688605bb94d656269e22b460cdb3c83 571 PRINTS PR00344 Bacterial sensor protein C-terminal signature 539 552 3.0E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS02525 9688605bb94d656269e22b460cdb3c83 571 PRINTS PR00344 Bacterial sensor protein C-terminal signature 498 508 3.0E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS02525 9688605bb94d656269e22b460cdb3c83 571 SUPERFAMILY SSF47384 321 391 8.24E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CFK41_RS02525 9688605bb94d656269e22b460cdb3c83 571 Gene3D G3DSA:3.30.565.10 392 555 3.9E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS02525 9688605bb94d656269e22b460cdb3c83 571 Gene3D G3DSA:1.10.287.130 340 391 6.5E-15 T 28-03-2018 CFK41_RS02525 9688605bb94d656269e22b460cdb3c83 571 SMART SM00388 332 398 4.7E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CFK41_RS02525 9688605bb94d656269e22b460cdb3c83 571 SMART SM00387 443 555 2.0E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS02525 9688605bb94d656269e22b460cdb3c83 571 SUPERFAMILY SSF55785 197 324 1.3E-7 T 28-03-2018 IPR000014 PAS domain CFK41_RS02525 9688605bb94d656269e22b460cdb3c83 571 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 444 554 8.2E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS02525 9688605bb94d656269e22b460cdb3c83 571 Pfam PF08448 PAS fold 214 324 5.3E-5 T 28-03-2018 IPR013656 PAS fold-4 CFK41_RS02525 9688605bb94d656269e22b460cdb3c83 571 Gene3D G3DSA:3.30.450.20 204 339 3.9E-13 T 28-03-2018 CFK41_RS09440 6b7e9028d96cd2a7df2ea728d06c5dd4 1526 Pfam PF01645 Conserved region in glutamate synthase 817 1179 3.1E-148 T 28-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 CFK41_RS09440 6b7e9028d96cd2a7df2ea728d06c5dd4 1526 Gene3D G3DSA:3.20.20.70 796 1239 3.1E-150 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS09440 6b7e9028d96cd2a7df2ea728d06c5dd4 1526 Pfam PF01493 GXGXG motif 1268 1433 5.4E-61 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CFK41_RS09440 6b7e9028d96cd2a7df2ea728d06c5dd4 1526 Pfam PF00310 Glutamine amidotransferases class-II 27 437 1.7E-161 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CFK41_RS09440 6b7e9028d96cd2a7df2ea728d06c5dd4 1526 Pfam PF04898 Glutamate synthase central domain 463 751 1.9E-109 T 28-03-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 CFK41_RS09440 6b7e9028d96cd2a7df2ea728d06c5dd4 1526 Gene3D G3DSA:3.60.20.10 27 444 3.9E-155 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CFK41_RS09440 6b7e9028d96cd2a7df2ea728d06c5dd4 1526 SUPERFAMILY SSF56235 27 440 1.08E-140 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CFK41_RS09440 6b7e9028d96cd2a7df2ea728d06c5dd4 1526 Gene3D G3DSA:2.160.20.60 1241 1515 3.5E-81 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CFK41_RS09440 6b7e9028d96cd2a7df2ea728d06c5dd4 1526 SUPERFAMILY SSF51395 451 1199 2.32E-255 T 28-03-2018 CFK41_RS09440 6b7e9028d96cd2a7df2ea728d06c5dd4 1526 SUPERFAMILY SSF69336 1235 1494 6.54E-68 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CFK41_RS09440 6b7e9028d96cd2a7df2ea728d06c5dd4 1526 Gene3D G3DSA:3.20.20.70 445 795 1.2E-96 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS13240 40bfc73ce79f603990cbe25c61b86162 211 Pfam PF01865 Protein of unknown function DUF47 8 111 2.1E-6 T 28-03-2018 IPR018445 Putative phosphate transport regulator CFK41_RS04005 1054d98201a4c90e601c25b09b1a28e0 179 Gene3D G3DSA:3.90.470.20 17 102 8.3E-7 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CFK41_RS04005 1054d98201a4c90e601c25b09b1a28e0 179 SUPERFAMILY SSF56214 94 176 6.8E-12 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CFK41_RS04005 1054d98201a4c90e601c25b09b1a28e0 179 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 94 156 5.3E-9 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CFK41_RS04005 1054d98201a4c90e601c25b09b1a28e0 179 Gene3D G3DSA:3.90.470.20 103 174 1.8E-8 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CFK41_RS14680 71409313f0a01b83ae17a40f0d8b19ae 432 Gene3D G3DSA:3.40.190.10 37 170 3.3E-16 T 28-03-2018 CFK41_RS14680 71409313f0a01b83ae17a40f0d8b19ae 432 Gene3D G3DSA:3.40.190.10 171 365 4.1E-36 T 28-03-2018 CFK41_RS14680 71409313f0a01b83ae17a40f0d8b19ae 432 SUPERFAMILY SSF53850 22 426 2.12E-68 T 28-03-2018 CFK41_RS14680 71409313f0a01b83ae17a40f0d8b19ae 432 Pfam PF01547 Bacterial extracellular solute-binding protein 51 336 1.3E-38 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CFK41_RS04185 79c078b69940a37afe02e0acb97174c3 427 Pfam PF13416 Bacterial extracellular solute-binding protein 61 364 3.6E-25 T 28-03-2018 CFK41_RS04185 79c078b69940a37afe02e0acb97174c3 427 SUPERFAMILY SSF53850 34 423 2.72E-43 T 28-03-2018 CFK41_RS04185 79c078b69940a37afe02e0acb97174c3 427 Gene3D G3DSA:3.40.190.10 165 352 1.7E-30 T 28-03-2018 CFK41_RS04185 79c078b69940a37afe02e0acb97174c3 427 Gene3D G3DSA:3.40.190.10 43 164 1.4E-8 T 28-03-2018 CFK41_RS10425 9e4d228e44a16092360f033e9b2555c4 494 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 9 489 3.1E-210 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CFK41_RS10425 9e4d228e44a16092360f033e9b2555c4 494 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 5 491 48.32 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CFK41_RS10425 9e4d228e44a16092360f033e9b2555c4 494 Gene3D G3DSA:3.50.50.60 5 463 1.8E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS10425 9e4d228e44a16092360f033e9b2555c4 494 SUPERFAMILY SSF51905 315 321 2.03E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS10425 9e4d228e44a16092360f033e9b2555c4 494 SUPERFAMILY SSF51905 8 274 2.03E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS10425 9e4d228e44a16092360f033e9b2555c4 494 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 8 491 3.3E-216 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CFK41_RS07600 53daf538f39ad5f7d582c973d45c1b81 204 SUPERFAMILY SSF48150 7 193 1.29E-33 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CFK41_RS07600 53daf538f39ad5f7d582c973d45c1b81 204 Gene3D G3DSA:1.10.1670.10 121 200 1.0E-7 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CFK41_RS07600 53daf538f39ad5f7d582c973d45c1b81 204 Gene3D G3DSA:1.10.340.30 19 120 3.5E-20 T 28-03-2018 CFK41_RS07600 53daf538f39ad5f7d582c973d45c1b81 204 SMART SM00478 36 193 3.6E-6 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CFK41_RS07600 53daf538f39ad5f7d582c973d45c1b81 204 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 32 134 1.7E-8 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CFK41_RS07600 53daf538f39ad5f7d582c973d45c1b81 204 PIRSF PIRSF001435 3 200 1.9E-40 T 28-03-2018 CFK41_RS00440 ece41f54b9199143b3704ca99f3536ca 287 Gene3D G3DSA:3.40.960.10 179 276 2.1E-16 T 28-03-2018 CFK41_RS00440 ece41f54b9199143b3704ca99f3536ca 287 SUPERFAMILY SSF52980 165 275 2.09E-13 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CFK41_RS02250 533ce9782d5c13fc589284c71d0895a9 641 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 1 641 28.837 T 28-03-2018 IPR023051 Potassium uptake protein, low affinity, Kup CFK41_RS02250 533ce9782d5c13fc589284c71d0895a9 641 Pfam PF02705 K+ potassium transporter 2 539 1.8E-183 T 28-03-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 CFK41_RS04915 639a3abf463bc23fbe4a146c9ed11f74 171 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 30 144 1.3E-17 T 28-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CFK41_RS04915 639a3abf463bc23fbe4a146c9ed11f74 171 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 84 144 4.0E-4 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CFK41_RS04915 639a3abf463bc23fbe4a146c9ed11f74 171 SUPERFAMILY SSF56214 30 143 8.63E-22 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CFK41_RS04915 639a3abf463bc23fbe4a146c9ed11f74 171 Gene3D G3DSA:3.90.470.20 26 154 4.8E-29 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CFK41_RS04915 639a3abf463bc23fbe4a146c9ed11f74 171 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 30 144 2.3E-19 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CFK41_RS04915 639a3abf463bc23fbe4a146c9ed11f74 171 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 31 144 20.147 T 28-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CFK41_RS04915 639a3abf463bc23fbe4a146c9ed11f74 171 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 32 138 1.5E-11 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CFK41_RS13745 65efb661863500f3958e2645d52b4baa 505 Gene3D G3DSA:2.30.40.10 1 105 7.7E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS13745 65efb661863500f3958e2645d52b4baa 505 SUPERFAMILY SSF51556 55 76 2.54E-31 T 28-03-2018 IPR032466 Metal-dependent hydrolase CFK41_RS13745 65efb661863500f3958e2645d52b4baa 505 SUPERFAMILY SSF51556 107 129 2.54E-31 T 28-03-2018 IPR032466 Metal-dependent hydrolase CFK41_RS13745 65efb661863500f3958e2645d52b4baa 505 SUPERFAMILY SSF51556 182 440 2.54E-31 T 28-03-2018 IPR032466 Metal-dependent hydrolase CFK41_RS13745 65efb661863500f3958e2645d52b4baa 505 Pfam PF07969 Amidohydrolase family 50 500 7.1E-40 T 28-03-2018 IPR013108 Amidohydrolase 3 CFK41_RS13745 65efb661863500f3958e2645d52b4baa 505 Gene3D G3DSA:3.20.20.140 165 444 5.0E-42 T 28-03-2018 CFK41_RS13745 65efb661863500f3958e2645d52b4baa 505 SUPERFAMILY SSF51338 2 64 4.19E-5 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS05750 5fea57d1d93c6c8a29e3eae585eb993f 302 Pfam PF00704 Glycosyl hydrolases family 18 68 266 1.1E-15 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CFK41_RS05750 5fea57d1d93c6c8a29e3eae585eb993f 302 Gene3D G3DSA:3.20.20.80 44 296 9.4E-36 T 28-03-2018 CFK41_RS05750 5fea57d1d93c6c8a29e3eae585eb993f 302 SUPERFAMILY SSF51445 39 278 2.8E-55 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS05750 5fea57d1d93c6c8a29e3eae585eb993f 302 ProSitePatterns PS01095 Chitinases family 18 active site. 153 161 - T 28-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CFK41_RS10545 52a118dba64a64ab3d9b27c90fdd2e74 413 SUPERFAMILY SSF56112 24 197 3.06E-9 T 28-03-2018 IPR011009 Protein kinase-like domain CFK41_RS10545 52a118dba64a64ab3d9b27c90fdd2e74 413 Pfam PF13224 Domain of unknown function (DUF4032) 229 391 2.8E-70 T 28-03-2018 IPR025111 Domain of unknown function DUF4032 CFK41_RS10545 52a118dba64a64ab3d9b27c90fdd2e74 413 Gene3D G3DSA:1.10.510.10 57 375 1.3E-5 T 28-03-2018 CFK41_RS10545 52a118dba64a64ab3d9b27c90fdd2e74 413 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 59 191 4.7E-5 T 28-03-2018 IPR010440 Lipopolysaccharide kinase GO:0005524|GO:0016020|GO:0016773 Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 CFK41_RS17135 68a9c922eda89a36d42555ca1b8504bc 275 SUPERFAMILY SSF51658 2 257 1.33E-28 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS17135 68a9c922eda89a36d42555ca1b8504bc 275 Gene3D G3DSA:3.20.20.150 1 261 8.6E-34 T 28-03-2018 CFK41_RS17135 68a9c922eda89a36d42555ca1b8504bc 275 Pfam PF01261 Xylose isomerase-like TIM barrel 29 197 3.8E-21 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS15305 62125f6bb892a49de8081f6c0d21bd87 282 PRINTS PR00069 Aldo-keto reductase signature 37 61 1.2E-45 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS15305 62125f6bb892a49de8081f6c0d21bd87 282 PRINTS PR00069 Aldo-keto reductase signature 125 142 1.2E-45 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS15305 62125f6bb892a49de8081f6c0d21bd87 282 PRINTS PR00069 Aldo-keto reductase signature 93 111 1.2E-45 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS15305 62125f6bb892a49de8081f6c0d21bd87 282 PRINTS PR00069 Aldo-keto reductase signature 159 188 1.2E-45 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS15305 62125f6bb892a49de8081f6c0d21bd87 282 PRINTS PR00069 Aldo-keto reductase signature 197 221 1.2E-45 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS15305 62125f6bb892a49de8081f6c0d21bd87 282 Gene3D G3DSA:3.20.20.100 1 278 1.0E-86 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS15305 62125f6bb892a49de8081f6c0d21bd87 282 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 41 58 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CFK41_RS15305 62125f6bb892a49de8081f6c0d21bd87 282 SUPERFAMILY SSF51430 6 266 2.1E-85 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS15305 62125f6bb892a49de8081f6c0d21bd87 282 Pfam PF00248 Aldo/keto reductase family 18 261 5.5E-47 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS15305 62125f6bb892a49de8081f6c0d21bd87 282 PIRSF PIRSF000097 113 280 9.0E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS15305 62125f6bb892a49de8081f6c0d21bd87 282 PIRSF PIRSF000097 1 118 5.8E-32 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS16145 0a18ef69b0def5a718ba6068da3db537 605 Pfam PF00664 ABC transporter transmembrane region 49 319 5.2E-40 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS16145 0a18ef69b0def5a718ba6068da3db537 605 Gene3D G3DSA:3.40.50.300 352 605 5.9E-68 T 28-03-2018 CFK41_RS16145 0a18ef69b0def5a718ba6068da3db537 605 ProSitePatterns PS00211 ABC transporters family signature. 503 517 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS16145 0a18ef69b0def5a718ba6068da3db537 605 Gene3D G3DSA:1.20.1560.10 7 351 1.5E-62 T 28-03-2018 CFK41_RS16145 0a18ef69b0def5a718ba6068da3db537 605 SMART SM00382 391 577 6.5E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS16145 0a18ef69b0def5a718ba6068da3db537 605 Pfam PF00005 ABC transporter 382 531 8.2E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS16145 0a18ef69b0def5a718ba6068da3db537 605 SUPERFAMILY SSF90123 34 355 4.32E-70 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS16145 0a18ef69b0def5a718ba6068da3db537 605 SUPERFAMILY SSF52540 355 601 2.61E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS14750 2826f155db07f63bfc706fdcedefaf70 207 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 24 38 5.1E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS14750 2826f155db07f63bfc706fdcedefaf70 207 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 54 5.1E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS14750 2826f155db07f63bfc706fdcedefaf70 207 Pfam PF07729 FCD domain 74 193 2.1E-22 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS14750 2826f155db07f63bfc706fdcedefaf70 207 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 64 7.9E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS14750 2826f155db07f63bfc706fdcedefaf70 207 SUPERFAMILY SSF46785 5 68 1.06E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS14750 2826f155db07f63bfc706fdcedefaf70 207 SMART SM00895 74 195 8.3E-18 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS14750 2826f155db07f63bfc706fdcedefaf70 207 SMART SM00345 6 64 1.9E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS14750 2826f155db07f63bfc706fdcedefaf70 207 Gene3D G3DSA:1.10.10.10 2 71 1.0E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS14750 2826f155db07f63bfc706fdcedefaf70 207 Gene3D G3DSA:1.20.120.530 72 206 2.1E-27 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS14750 2826f155db07f63bfc706fdcedefaf70 207 SUPERFAMILY SSF48008 69 203 7.06E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS13625 d5f7d705f6de32f3fe77b1155d569cf8 579 SMART SM01016 6 87 5.2E-28 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CFK41_RS13625 d5f7d705f6de32f3fe77b1155d569cf8 579 PRINTS PR01038 Arginyl-tRNA synthetase signature 155 168 4.3E-25 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CFK41_RS13625 d5f7d705f6de32f3fe77b1155d569cf8 579 PRINTS PR01038 Arginyl-tRNA synthetase signature 116 131 4.3E-25 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CFK41_RS13625 d5f7d705f6de32f3fe77b1155d569cf8 579 PRINTS PR01038 Arginyl-tRNA synthetase signature 131 147 4.3E-25 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CFK41_RS13625 d5f7d705f6de32f3fe77b1155d569cf8 579 PRINTS PR01038 Arginyl-tRNA synthetase signature 306 327 4.3E-25 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CFK41_RS13625 d5f7d705f6de32f3fe77b1155d569cf8 579 Gene3D G3DSA:1.10.730.10 445 579 1.9E-42 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS13625 d5f7d705f6de32f3fe77b1155d569cf8 579 Pfam PF05746 DALR anticodon binding domain 463 579 3.2E-32 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CFK41_RS13625 d5f7d705f6de32f3fe77b1155d569cf8 579 Gene3D G3DSA:3.40.50.620 109 444 1.4E-43 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS13625 d5f7d705f6de32f3fe77b1155d569cf8 579 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 124 135 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS13625 d5f7d705f6de32f3fe77b1155d569cf8 579 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 32 579 1.8E-140 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CFK41_RS13625 d5f7d705f6de32f3fe77b1155d569cf8 579 Hamap MF_00123 Arginine--tRNA ligase [argS]. 6 579 25.079 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CFK41_RS13625 d5f7d705f6de32f3fe77b1155d569cf8 579 SMART SM00836 463 579 1.2E-36 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CFK41_RS13625 d5f7d705f6de32f3fe77b1155d569cf8 579 SUPERFAMILY SSF52374 111 454 1.65E-78 T 28-03-2018 CFK41_RS13625 d5f7d705f6de32f3fe77b1155d569cf8 579 Pfam PF00750 tRNA synthetases class I (R) 112 448 5.5E-99 T 28-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 CFK41_RS13625 d5f7d705f6de32f3fe77b1155d569cf8 579 SUPERFAMILY SSF55190 9 98 3.53E-19 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CFK41_RS13625 d5f7d705f6de32f3fe77b1155d569cf8 579 Gene3D G3DSA:3.30.1360.70 3 104 3.5E-23 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CFK41_RS13625 d5f7d705f6de32f3fe77b1155d569cf8 579 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 8 87 1.3E-20 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CFK41_RS13625 d5f7d705f6de32f3fe77b1155d569cf8 579 SUPERFAMILY SSF47323 457 579 2.49E-32 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS10370 3b68849edbe194541365811ab1000f11 111 Gene3D G3DSA:2.20.28.10 13 42 0.0012 T 28-03-2018 CFK41_RS10370 3b68849edbe194541365811ab1000f11 111 Pfam PF09723 Zinc ribbon domain 2 41 7.2E-14 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CFK41_RS10370 3b68849edbe194541365811ab1000f11 111 Gene3D G3DSA:2.20.25.10 2 12 0.0042 T 28-03-2018 CFK41_RS10370 3b68849edbe194541365811ab1000f11 111 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 2 52 2.8E-18 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CFK41_RS10370 3b68849edbe194541365811ab1000f11 111 SMART SM00834 2 42 3.1E-11 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CFK41_RS00040 dd73f118ec664adc3a1757a3cdb6ab9c 392 SUPERFAMILY SSF103473 9 384 2.75E-33 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS00040 dd73f118ec664adc3a1757a3cdb6ab9c 392 Gene3D G3DSA:1.20.1250.20 5 188 2.0E-8 T 28-03-2018 CFK41_RS00040 dd73f118ec664adc3a1757a3cdb6ab9c 392 Pfam PF07690 Major Facilitator Superfamily 30 329 5.6E-18 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS00040 dd73f118ec664adc3a1757a3cdb6ab9c 392 Gene3D G3DSA:1.20.1250.20 206 388 3.5E-18 T 28-03-2018 CFK41_RS15835 0b53149c94aba7d5429ec70eef172bf7 1297 Gene3D G3DSA:2.60.120.260 1105 1290 6.9E-11 T 28-03-2018 IPR008979 Galactose-binding domain-like CFK41_RS15835 0b53149c94aba7d5429ec70eef172bf7 1297 Gene3D G3DSA:2.60.120.260 798 973 3.6E-14 T 28-03-2018 IPR008979 Galactose-binding domain-like CFK41_RS15835 0b53149c94aba7d5429ec70eef172bf7 1297 SUPERFAMILY SSF56496 78 131 3.74E-10 T 28-03-2018 IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain CFK41_RS15835 0b53149c94aba7d5429ec70eef172bf7 1297 Gene3D G3DSA:2.130.10.10 340 568 7.2E-7 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CFK41_RS15835 0b53149c94aba7d5429ec70eef172bf7 1297 SUPERFAMILY SSF50969 352 598 3.06E-5 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like CFK41_RS15835 0b53149c94aba7d5429ec70eef172bf7 1297 Gene3D G3DSA:2.60.40.10 702 797 5.2E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS15835 0b53149c94aba7d5429ec70eef172bf7 1297 SUPERFAMILY SSF49785 808 955 5.42E-8 T 28-03-2018 IPR008979 Galactose-binding domain-like CFK41_RS15835 0b53149c94aba7d5429ec70eef172bf7 1297 Gene3D G3DSA:3.90.215.10 75 256 5.6E-10 T 28-03-2018 IPR014716 Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 CFK41_RS09935 d51946137ce98ac5100c6080b8662840 805 SUPERFAMILY SSF81271 436 507 1.59E-20 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CFK41_RS09935 d51946137ce98ac5100c6080b8662840 805 Gene3D G3DSA:3.30.70.260 716 796 1.8E-11 T 28-03-2018 CFK41_RS09935 d51946137ce98ac5100c6080b8662840 805 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 85 788 5.1E-242 T 28-03-2018 IPR004811 RelA/SpoT family GO:0015969 CFK41_RS09935 d51946137ce98ac5100c6080b8662840 805 SUPERFAMILY SSF81301 237 452 8.5E-62 T 28-03-2018 CFK41_RS09935 d51946137ce98ac5100c6080b8662840 805 Pfam PF13328 HD domain 85 232 3.1E-46 T 28-03-2018 IPR003607 HD/PDEase domain CFK41_RS09935 d51946137ce98ac5100c6080b8662840 805 SMART SM00954 292 402 1.0E-62 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CFK41_RS09935 d51946137ce98ac5100c6080b8662840 805 Pfam PF13291 ACT domain 712 788 5.7E-18 T 28-03-2018 IPR002912 ACT domain CFK41_RS09935 d51946137ce98ac5100c6080b8662840 805 Gene3D G3DSA:3.10.20.30 442 514 2.4E-25 T 28-03-2018 IPR012675 Beta-grasp domain CFK41_RS09935 d51946137ce98ac5100c6080b8662840 805 SUPERFAMILY SSF55021 713 790 8.24E-11 T 28-03-2018 CFK41_RS09935 d51946137ce98ac5100c6080b8662840 805 SUPERFAMILY SSF109604 62 247 7.38E-68 T 28-03-2018 CFK41_RS09935 d51946137ce98ac5100c6080b8662840 805 SMART SM00471 100 210 9.2E-12 T 28-03-2018 IPR003607 HD/PDEase domain CFK41_RS09935 d51946137ce98ac5100c6080b8662840 805 Pfam PF04607 Region found in RelA / SpoT proteins 292 400 4.4E-36 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CFK41_RS09935 d51946137ce98ac5100c6080b8662840 805 Gene3D G3DSA:3.30.460.10 249 382 1.9E-44 T 28-03-2018 CFK41_RS09935 d51946137ce98ac5100c6080b8662840 805 Pfam PF02824 TGS domain 448 507 8.7E-21 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CFK41_RS06960 d66c3c0767d705b0412394e138b0f6fa 352 Gene3D G3DSA:3.40.50.1100 40 146 2.2E-25 T 28-03-2018 CFK41_RS06960 d66c3c0767d705b0412394e138b0f6fa 352 Gene3D G3DSA:3.40.50.1100 147 334 9.7E-48 T 28-03-2018 CFK41_RS06960 d66c3c0767d705b0412394e138b0f6fa 352 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 53 66 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CFK41_RS06960 d66c3c0767d705b0412394e138b0f6fa 352 PIRSF PIRSF038945 1 352 4.3E-156 T 28-03-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 CFK41_RS06960 d66c3c0767d705b0412394e138b0f6fa 352 SUPERFAMILY SSF53686 6 333 2.1E-97 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CFK41_RS06960 d66c3c0767d705b0412394e138b0f6fa 352 TIGRFAM TIGR00260 thrC: threonine synthase 11 326 1.4E-89 T 28-03-2018 IPR004450 Threonine synthase-like CFK41_RS06960 d66c3c0767d705b0412394e138b0f6fa 352 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 26 319 2.2E-70 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CFK41_RS01370 e6b4d3c19a56deca4ec64fb9dad5aa31 276 SUPERFAMILY SSF161098 2 276 5.05E-58 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01370 e6b4d3c19a56deca4ec64fb9dad5aa31 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 269 2.0E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01370 e6b4d3c19a56deca4ec64fb9dad5aa31 276 Gene3D G3DSA:1.10.3720.10 1 263 3.3E-37 T 28-03-2018 CFK41_RS06260 5e7148abdfb1f2b3415d5977577e5b23 99 Pfam PF02467 Transcription factor WhiB 31 94 1.6E-27 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain CFK41_RS06260 5e7148abdfb1f2b3415d5977577e5b23 99 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 99 19.261 T 28-03-2018 IPR003482 Transcription factor WhiB CFK41_RS09525 f21315331274253120c30b9f37e3592d 401 Gene3D G3DSA:3.40.50.880 165 395 2.8E-48 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS09525 f21315331274253120c30b9f37e3592d 401 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 286 303 3.4E-30 T 28-03-2018 CFK41_RS09525 f21315331274253120c30b9f37e3592d 401 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 311 322 3.4E-30 T 28-03-2018 CFK41_RS09525 f21315331274253120c30b9f37e3592d 401 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 238 252 3.4E-30 T 28-03-2018 CFK41_RS09525 f21315331274253120c30b9f37e3592d 401 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 269 285 3.4E-30 T 28-03-2018 CFK41_RS09525 f21315331274253120c30b9f37e3592d 401 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 199 213 3.4E-30 T 28-03-2018 CFK41_RS09525 f21315331274253120c30b9f37e3592d 401 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 21 149 1.9E-48 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CFK41_RS09525 f21315331274253120c30b9f37e3592d 401 PRINTS PR00096 Glutamine amidotransferase superfamily signature 241 250 3.0E-10 T 28-03-2018 CFK41_RS09525 f21315331274253120c30b9f37e3592d 401 PRINTS PR00096 Glutamine amidotransferase superfamily signature 365 378 3.0E-10 T 28-03-2018 CFK41_RS09525 f21315331274253120c30b9f37e3592d 401 PRINTS PR00096 Glutamine amidotransferase superfamily signature 269 280 3.0E-10 T 28-03-2018 CFK41_RS09525 f21315331274253120c30b9f37e3592d 401 Gene3D G3DSA:3.50.30.20 19 164 3.1E-58 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CFK41_RS09525 f21315331274253120c30b9f37e3592d 401 Pfam PF00117 Glutamine amidotransferase class-I 203 387 7.4E-36 T 28-03-2018 IPR017926 Glutamine amidotransferase CFK41_RS09525 f21315331274253120c30b9f37e3592d 401 SMART SM01097 20 150 2.3E-81 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CFK41_RS09525 f21315331274253120c30b9f37e3592d 401 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 20 394 43.987 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CFK41_RS09525 f21315331274253120c30b9f37e3592d 401 PRINTS PR00097 Anthranilate synthase component II signature 269 280 9.5E-5 T 28-03-2018 CFK41_RS09525 f21315331274253120c30b9f37e3592d 401 PRINTS PR00097 Anthranilate synthase component II signature 241 250 9.5E-5 T 28-03-2018 CFK41_RS09525 f21315331274253120c30b9f37e3592d 401 PRINTS PR00097 Anthranilate synthase component II signature 365 378 9.5E-5 T 28-03-2018 CFK41_RS09525 f21315331274253120c30b9f37e3592d 401 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 22 388 1.1E-127 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CFK41_RS09525 f21315331274253120c30b9f37e3592d 401 SUPERFAMILY SSF52317 177 393 7.99E-47 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS09525 f21315331274253120c30b9f37e3592d 401 SUPERFAMILY SSF52021 21 155 1.06E-52 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CFK41_RS14215 d6eab8cd828ea5e330ea9aaa9c9841d2 771 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 411 626 9.8E-25 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CFK41_RS14215 d6eab8cd828ea5e330ea9aaa9c9841d2 771 SUPERFAMILY SSF52279 410 616 1.7E-18 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CFK41_RS14215 d6eab8cd828ea5e330ea9aaa9c9841d2 771 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 94 364 5.3E-56 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS14215 d6eab8cd828ea5e330ea9aaa9c9841d2 771 Gene3D G3DSA:3.40.50.1700 395 644 1.6E-37 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CFK41_RS14215 d6eab8cd828ea5e330ea9aaa9c9841d2 771 Gene3D G3DSA:3.20.20.300 16 382 3.9E-78 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS14215 d6eab8cd828ea5e330ea9aaa9c9841d2 771 PRINTS PR00133 Glycosyl hydrolase family 3 signature 218 234 1.5E-15 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS14215 d6eab8cd828ea5e330ea9aaa9c9841d2 771 PRINTS PR00133 Glycosyl hydrolase family 3 signature 132 151 1.5E-15 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS14215 d6eab8cd828ea5e330ea9aaa9c9841d2 771 PRINTS PR00133 Glycosyl hydrolase family 3 signature 109 125 1.5E-15 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS14215 d6eab8cd828ea5e330ea9aaa9c9841d2 771 PRINTS PR00133 Glycosyl hydrolase family 3 signature 178 194 1.5E-15 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS14215 d6eab8cd828ea5e330ea9aaa9c9841d2 771 PRINTS PR00133 Glycosyl hydrolase family 3 signature 288 306 1.5E-15 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS14215 d6eab8cd828ea5e330ea9aaa9c9841d2 771 SUPERFAMILY SSF51445 74 374 1.47E-72 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS14215 d6eab8cd828ea5e330ea9aaa9c9841d2 771 SUPERFAMILY SSF51445 10 42 1.47E-72 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS13355 17d2d7b651dd40d8572daedb9334718f 478 Pfam PF16257 tagaturonate epimerase 43 469 4.4E-125 T 28-03-2018 IPR032586 Tagaturonate epimerase CFK41_RS13355 17d2d7b651dd40d8572daedb9334718f 478 Gene3D G3DSA:3.20.20.150 175 236 0.052 T 28-03-2018 CFK41_RS06915 c5466d60d7878d0d8c08c30934c8a30b 1292 SUPERFAMILY SSF52777 169 411 3.47E-49 T 28-03-2018 CFK41_RS06915 c5466d60d7878d0d8c08c30934c8a30b 1292 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 448 1289 0.0 T 28-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CFK41_RS06915 c5466d60d7878d0d8c08c30934c8a30b 1292 Gene3D G3DSA:3.40.50.970 525 881 3.2E-87 T 28-03-2018 CFK41_RS06915 c5466d60d7878d0d8c08c30934c8a30b 1292 Pfam PF02779 Transketolase, pyrimidine binding domain 955 1148 1.7E-57 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CFK41_RS06915 c5466d60d7878d0d8c08c30934c8a30b 1292 Pfam PF00676 Dehydrogenase E1 component 569 882 1.1E-55 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CFK41_RS06915 c5466d60d7878d0d8c08c30934c8a30b 1292 SUPERFAMILY SSF52518 942 1155 1.86E-46 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CFK41_RS06915 c5466d60d7878d0d8c08c30934c8a30b 1292 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 1152 1290 6.8E-45 T 28-03-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CFK41_RS06915 c5466d60d7878d0d8c08c30934c8a30b 1292 Gene3D G3DSA:3.40.50.970 951 1162 2.5E-54 T 28-03-2018 CFK41_RS06915 c5466d60d7878d0d8c08c30934c8a30b 1292 SMART SM00861 955 1148 1.6E-52 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CFK41_RS06915 c5466d60d7878d0d8c08c30934c8a30b 1292 SUPERFAMILY SSF52518 479 881 2.09E-85 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CFK41_RS06915 c5466d60d7878d0d8c08c30934c8a30b 1292 Gene3D G3DSA:3.30.559.10 161 412 1.8E-46 T 28-03-2018 CFK41_RS06915 c5466d60d7878d0d8c08c30934c8a30b 1292 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 178 409 1.3E-47 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CFK41_RS06915 c5466d60d7878d0d8c08c30934c8a30b 1292 Gene3D G3DSA:1.10.287.1150 443 524 8.2E-23 T 28-03-2018 CFK41_RS06915 c5466d60d7878d0d8c08c30934c8a30b 1292 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 9 44 2.3E-10 T 28-03-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CFK41_RS04255 ef9459d2cf8830c9cb15396c8006f3d9 217 SUPERFAMILY SSF81296 41 133 1.19E-22 T 28-03-2018 IPR014756 Immunoglobulin E-set CFK41_RS04255 ef9459d2cf8830c9cb15396c8006f3d9 217 Gene3D G3DSA:2.60.40.1220 41 136 2.3E-26 T 28-03-2018 CFK41_RS04255 ef9459d2cf8830c9cb15396c8006f3d9 217 Pfam PF04234 CopC domain 42 132 4.9E-23 T 28-03-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 CFK41_RS12320 a0e3e9f9448e3fd20fda382f2e14b180 332 SUPERFAMILY SSF51735 1 316 1.23E-82 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS12320 a0e3e9f9448e3fd20fda382f2e14b180 332 Gene3D G3DSA:3.40.50.720 1 172 7.7E-31 T 28-03-2018 CFK41_RS12320 a0e3e9f9448e3fd20fda382f2e14b180 332 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 4 318 1.3E-94 T 28-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 CFK41_RS12320 a0e3e9f9448e3fd20fda382f2e14b180 332 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 251 1.4E-51 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CFK41_RS12320 a0e3e9f9448e3fd20fda382f2e14b180 332 Gene3D G3DSA:3.90.25.10 173 323 2.4E-33 T 28-03-2018 CFK41_RS06830 affd1b6027c8ebd8096a640a6c1248d7 1564 SUPERFAMILY SSF52540 36 225 1.08E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS06830 affd1b6027c8ebd8096a640a6c1248d7 1564 SUPERFAMILY SSF52540 265 418 1.08E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS06830 affd1b6027c8ebd8096a640a6c1248d7 1564 Pfam PF00271 Helicase conserved C-terminal domain 295 414 8.8E-13 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS06830 affd1b6027c8ebd8096a640a6c1248d7 1564 Gene3D G3DSA:3.40.50.300 273 443 3.0E-24 T 28-03-2018 CFK41_RS06830 affd1b6027c8ebd8096a640a6c1248d7 1564 Gene3D G3DSA:3.40.50.300 8 250 8.4E-36 T 28-03-2018 CFK41_RS06830 affd1b6027c8ebd8096a640a6c1248d7 1564 SMART SM00487 23 252 3.9E-32 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CFK41_RS06830 affd1b6027c8ebd8096a640a6c1248d7 1564 SMART SM00490 311 414 1.3E-12 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS06830 affd1b6027c8ebd8096a640a6c1248d7 1564 Pfam PF00270 DEAD/DEAH box helicase 28 223 3.2E-23 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CFK41_RS06830 affd1b6027c8ebd8096a640a6c1248d7 1564 Pfam PF08494 DEAD/H associated 678 865 9.3E-70 T 28-03-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 CFK41_RS05820 a02e7ad5e1f0329c665e3dfd3e88fa09 490 ProSitePatterns PS00163 Fumarate lyases signature. 300 309 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CFK41_RS05820 a02e7ad5e1f0329c665e3dfd3e88fa09 490 PRINTS PR00145 Argininosuccinate lyase family signature 167 187 4.2E-50 T 28-03-2018 CFK41_RS05820 a02e7ad5e1f0329c665e3dfd3e88fa09 490 PRINTS PR00145 Argininosuccinate lyase family signature 300 316 4.2E-50 T 28-03-2018 CFK41_RS05820 a02e7ad5e1f0329c665e3dfd3e88fa09 490 PRINTS PR00145 Argininosuccinate lyase family signature 256 280 4.2E-50 T 28-03-2018 CFK41_RS05820 a02e7ad5e1f0329c665e3dfd3e88fa09 490 PRINTS PR00145 Argininosuccinate lyase family signature 335 354 4.2E-50 T 28-03-2018 CFK41_RS05820 a02e7ad5e1f0329c665e3dfd3e88fa09 490 PRINTS PR00145 Argininosuccinate lyase family signature 218 234 4.2E-50 T 28-03-2018 CFK41_RS05820 a02e7ad5e1f0329c665e3dfd3e88fa09 490 PRINTS PR00145 Argininosuccinate lyase family signature 126 148 4.2E-50 T 28-03-2018 CFK41_RS05820 a02e7ad5e1f0329c665e3dfd3e88fa09 490 TIGRFAM TIGR00838 argH: argininosuccinate lyase 27 477 1.2E-172 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CFK41_RS05820 a02e7ad5e1f0329c665e3dfd3e88fa09 490 Pfam PF14698 Argininosuccinate lyase C-terminal 388 456 1.1E-23 T 28-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CFK41_RS05820 a02e7ad5e1f0329c665e3dfd3e88fa09 490 Pfam PF00206 Lyase 39 325 6.7E-63 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CFK41_RS05820 a02e7ad5e1f0329c665e3dfd3e88fa09 490 Hamap MF_00006 Argininosuccinate lyase [argH]. 26 478 39.034 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CFK41_RS05820 a02e7ad5e1f0329c665e3dfd3e88fa09 490 SUPERFAMILY SSF48557 30 481 3.46E-131 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CFK41_RS05820 a02e7ad5e1f0329c665e3dfd3e88fa09 490 Gene3D G3DSA:1.10.40.30 400 457 1.2E-26 T 28-03-2018 CFK41_RS05820 a02e7ad5e1f0329c665e3dfd3e88fa09 490 Gene3D G3DSA:1.10.275.10 26 131 1.7E-31 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CFK41_RS05820 a02e7ad5e1f0329c665e3dfd3e88fa09 490 PRINTS PR00149 Fumarate lyase superfamily signature 172 190 3.3E-25 T 28-03-2018 IPR000362 Fumarate lyase family CFK41_RS05820 a02e7ad5e1f0329c665e3dfd3e88fa09 490 PRINTS PR00149 Fumarate lyase superfamily signature 127 145 3.3E-25 T 28-03-2018 IPR000362 Fumarate lyase family CFK41_RS05820 a02e7ad5e1f0329c665e3dfd3e88fa09 490 PRINTS PR00149 Fumarate lyase superfamily signature 256 283 3.3E-25 T 28-03-2018 IPR000362 Fumarate lyase family CFK41_RS05820 a02e7ad5e1f0329c665e3dfd3e88fa09 490 PRINTS PR00149 Fumarate lyase superfamily signature 300 316 3.3E-25 T 28-03-2018 IPR000362 Fumarate lyase family CFK41_RS05820 a02e7ad5e1f0329c665e3dfd3e88fa09 490 Gene3D G3DSA:1.20.200.10 132 399 1.3E-89 T 28-03-2018 CFK41_RS03430 a8500d12218d1d99ff7b4620b665f189 392 SUPERFAMILY SSF52540 17 217 6.3E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS03430 a8500d12218d1d99ff7b4620b665f189 392 Pfam PF13177 DNA polymerase III, delta subunit 23 177 7.0E-39 T 28-03-2018 CFK41_RS03430 a8500d12218d1d99ff7b4620b665f189 392 Gene3D G3DSA:1.20.272.10 286 392 3.6E-16 T 28-03-2018 CFK41_RS03430 a8500d12218d1d99ff7b4620b665f189 392 SMART SM00382 40 204 0.003 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS03430 a8500d12218d1d99ff7b4620b665f189 392 Gene3D G3DSA:3.40.50.300 17 179 1.1E-27 T 28-03-2018 CFK41_RS09635 d2324081a6d701586aa9861a35341ba6 152 Pfam PF14534 Domain of unknown function (DUF4440) 30 139 1.2E-7 T 28-03-2018 IPR027843 Domain of unknown function DUF4440 CFK41_RS09635 d2324081a6d701586aa9861a35341ba6 152 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 25 148 4.8E-15 T 28-03-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 CFK41_RS09635 d2324081a6d701586aa9861a35341ba6 152 Gene3D G3DSA:3.10.450.50 5 152 2.0E-15 T 28-03-2018 CFK41_RS09635 d2324081a6d701586aa9861a35341ba6 152 SUPERFAMILY SSF54427 21 150 1.09E-19 T 28-03-2018 IPR032710 NTF2-like domain CFK41_RS01730 e660cd3af121af260d3fb879e225b403 500 Gene3D G3DSA:3.40.190.10 323 449 1.3E-5 T 28-03-2018 CFK41_RS01730 e660cd3af121af260d3fb879e225b403 500 Pfam PF13416 Bacterial extracellular solute-binding protein 63 291 9.4E-17 T 28-03-2018 CFK41_RS01730 e660cd3af121af260d3fb879e225b403 500 Gene3D G3DSA:3.40.190.10 35 202 7.6E-28 T 28-03-2018 CFK41_RS01730 e660cd3af121af260d3fb879e225b403 500 SUPERFAMILY SSF53850 23 498 7.97E-75 T 28-03-2018 CFK41_RS12925 f7f6db3fe16ee24caf32a6bd9394540a 551 SUPERFAMILY SSF52540 146 345 8.07E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS12925 f7f6db3fe16ee24caf32a6bd9394540a 551 SMART SM00487 178 353 1.4E-20 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CFK41_RS12925 f7f6db3fe16ee24caf32a6bd9394540a 551 Gene3D G3DSA:3.40.50.300 172 355 1.7E-26 T 28-03-2018 CFK41_RS12925 f7f6db3fe16ee24caf32a6bd9394540a 551 SUPERFAMILY SSF52540 393 510 5.13E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS12925 f7f6db3fe16ee24caf32a6bd9394540a 551 SUPERFAMILY SSF52540 290 360 5.13E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS12925 f7f6db3fe16ee24caf32a6bd9394540a 551 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 353 541 1.8E-43 T 28-03-2018 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 CFK41_RS12925 f7f6db3fe16ee24caf32a6bd9394540a 551 Gene3D G3DSA:3.40.50.300 385 533 2.3E-18 T 28-03-2018 CFK41_RS12925 f7f6db3fe16ee24caf32a6bd9394540a 551 SMART SM00490 423 500 6.1E-10 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS12925 f7f6db3fe16ee24caf32a6bd9394540a 551 Pfam PF04851 Type III restriction enzyme, res subunit 181 326 2.0E-12 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CFK41_RS12925 f7f6db3fe16ee24caf32a6bd9394540a 551 Pfam PF13625 Helicase conserved C-terminal domain 6 134 4.8E-42 T 28-03-2018 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 CFK41_RS05925 199b422c57c1fc7b0da553bf108d6520 89 Gene3D G3DSA:1.10.287.850 1 89 3.9E-10 T 28-03-2018 CFK41_RS15270 280f3b674d18735c03ebe6fed23f4b8c 329 Gene3D G3DSA:3.40.50.920 195 327 7.0E-40 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CFK41_RS15270 280f3b674d18735c03ebe6fed23f4b8c 329 SUPERFAMILY SSF52922 194 326 1.44E-38 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CFK41_RS15270 280f3b674d18735c03ebe6fed23f4b8c 329 SUPERFAMILY SSF52518 4 205 2.82E-68 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CFK41_RS15270 280f3b674d18735c03ebe6fed23f4b8c 329 SMART SM00861 6 181 1.4E-66 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CFK41_RS15270 280f3b674d18735c03ebe6fed23f4b8c 329 Pfam PF02780 Transketolase, C-terminal domain 196 318 3.1E-39 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CFK41_RS15270 280f3b674d18735c03ebe6fed23f4b8c 329 Pfam PF02779 Transketolase, pyrimidine binding domain 5 180 2.2E-50 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CFK41_RS15270 280f3b674d18735c03ebe6fed23f4b8c 329 Gene3D G3DSA:3.40.50.970 2 194 3.3E-66 T 28-03-2018 CFK41_RS04960 c821c6749dc6d0d9f375b472d3ddee85 163 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 85 158 1.1E-12 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CFK41_RS04960 c821c6749dc6d0d9f375b472d3ddee85 163 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 21 52 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CFK41_RS04960 c821c6749dc6d0d9f375b472d3ddee85 163 Pfam PF03449 Transcription elongation factor, N-terminal 9 78 4.9E-26 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CFK41_RS04960 c821c6749dc6d0d9f375b472d3ddee85 163 Gene3D G3DSA:1.10.287.180 8 78 3.9E-26 T 28-03-2018 CFK41_RS04960 c821c6749dc6d0d9f375b472d3ddee85 163 PIRSF PIRSF006092 2 162 3.4E-34 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CFK41_RS04960 c821c6749dc6d0d9f375b472d3ddee85 163 SUPERFAMILY SSF46557 8 80 1.29E-22 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CFK41_RS04960 c821c6749dc6d0d9f375b472d3ddee85 163 Gene3D G3DSA:3.10.50.30 79 163 2.9E-15 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CFK41_RS04960 c821c6749dc6d0d9f375b472d3ddee85 163 SUPERFAMILY SSF54534 84 158 1.01E-10 T 28-03-2018 CFK41_RS04960 c821c6749dc6d0d9f375b472d3ddee85 163 Hamap MF_00105 Transcription elongation factor GreA [greA]. 6 159 26.294 T 28-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 CFK41_RS03135 892dca4150d0c464803dd764f8a09ff6 438 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 6 435 93.597 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CFK41_RS03135 892dca4150d0c464803dd764f8a09ff6 438 Gene3D G3DSA:3.40.640.10 175 322 8.9E-32 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS03135 892dca4150d0c464803dd764f8a09ff6 438 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 7 431 2.8E-166 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CFK41_RS03135 892dca4150d0c464803dd764f8a09ff6 438 Gene3D G3DSA:3.90.1150.10 323 437 1.1E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS03135 892dca4150d0c464803dd764f8a09ff6 438 Pfam PF00202 Aminotransferase class-III 37 428 3.3E-67 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CFK41_RS03135 892dca4150d0c464803dd764f8a09ff6 438 Gene3D G3DSA:3.90.1150.10 1 174 1.1E-41 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS03135 892dca4150d0c464803dd764f8a09ff6 438 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 241 281 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CFK41_RS03135 892dca4150d0c464803dd764f8a09ff6 438 SUPERFAMILY SSF53383 4 431 3.74E-105 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS09210 9da5a58d8cb2bdc02a2922647211eee5 80 PRINTS PR01651 Protein-export SecG membrane protein signature 26 40 1.3E-5 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CFK41_RS09210 9da5a58d8cb2bdc02a2922647211eee5 80 PRINTS PR01651 Protein-export SecG membrane protein signature 57 79 1.3E-5 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CFK41_RS09210 9da5a58d8cb2bdc02a2922647211eee5 80 PRINTS PR01651 Protein-export SecG membrane protein signature 6 26 1.3E-5 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CFK41_RS09210 9da5a58d8cb2bdc02a2922647211eee5 80 Pfam PF03840 Preprotein translocase SecG subunit 7 76 1.3E-15 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CFK41_RS09210 9da5a58d8cb2bdc02a2922647211eee5 80 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 6 76 1.5E-16 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CFK41_RS14885 ff72929ff72dabcb583e954718fdb249 486 Pfam PF07690 Major Facilitator Superfamily 84 406 2.8E-34 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS14885 ff72929ff72dabcb583e954718fdb249 486 Gene3D G3DSA:1.20.1250.20 62 263 2.4E-31 T 28-03-2018 CFK41_RS14885 ff72929ff72dabcb583e954718fdb249 486 Gene3D G3DSA:1.20.1250.20 267 480 3.8E-16 T 28-03-2018 CFK41_RS14885 ff72929ff72dabcb583e954718fdb249 486 SUPERFAMILY SSF103473 61 472 1.57E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS04730 7c7c4f90d08f82c4ce1665a45855a931 666 SMART SM00701 195 333 2.1E-41 T 28-03-2018 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CFK41_RS04730 7c7c4f90d08f82c4ce1665a45855a931 666 Gene3D G3DSA:3.40.80.10 186 392 7.2E-43 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CFK41_RS04730 7c7c4f90d08f82c4ce1665a45855a931 666 SMART SM00644 208 370 2.4E-5 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CFK41_RS04730 7c7c4f90d08f82c4ce1665a45855a931 666 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 219 370 2.7E-14 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CFK41_RS04730 7c7c4f90d08f82c4ce1665a45855a931 666 Pfam PF00395 S-layer homology domain 551 594 3.0E-9 T 28-03-2018 IPR001119 S-layer homology domain CFK41_RS04730 7c7c4f90d08f82c4ce1665a45855a931 666 Pfam PF00395 S-layer homology domain 614 656 1.8E-10 T 28-03-2018 IPR001119 S-layer homology domain CFK41_RS04730 7c7c4f90d08f82c4ce1665a45855a931 666 Pfam PF00395 S-layer homology domain 490 529 0.0028 T 28-03-2018 IPR001119 S-layer homology domain CFK41_RS04730 7c7c4f90d08f82c4ce1665a45855a931 666 SUPERFAMILY SSF55846 195 382 8.38E-46 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CFK41_RS10410 886a5d0591d9ca7f35cd615e8fa549e8 333 SUPERFAMILY SSF161098 87 317 2.09E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS10410 886a5d0591d9ca7f35cd615e8fa549e8 333 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 328 1.3E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS10410 886a5d0591d9ca7f35cd615e8fa549e8 333 Gene3D G3DSA:1.10.3720.10 43 331 1.1E-39 T 28-03-2018 CFK41_RS07065 f9751a371cd94df987351a36eb8c3253 495 SUPERFAMILY SSF50615 23 102 2.51E-23 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CFK41_RS07065 f9751a371cd94df987351a36eb8c3253 495 Gene3D G3DSA:1.10.1140.10 377 487 7.6E-36 T 28-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CFK41_RS07065 f9751a371cd94df987351a36eb8c3253 495 SMART SM00382 170 433 2.0E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS07065 f9751a371cd94df987351a36eb8c3253 495 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 23 487 1.1E-229 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CFK41_RS07065 f9751a371cd94df987351a36eb8c3253 495 Gene3D G3DSA:3.40.50.300 103 376 1.0E-88 T 28-03-2018 CFK41_RS07065 f9751a371cd94df987351a36eb8c3253 495 SUPERFAMILY SSF52540 104 376 2.44E-88 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS07065 f9751a371cd94df987351a36eb8c3253 495 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 26 100 2.1E-18 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CFK41_RS07065 f9751a371cd94df987351a36eb8c3253 495 Hamap MF_01347 ATP synthase subunit beta [atpB]. 21 489 53.9 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CFK41_RS07065 f9751a371cd94df987351a36eb8c3253 495 Gene3D G3DSA:2.40.10.170 14 102 4.4E-27 T 28-03-2018 CFK41_RS07065 f9751a371cd94df987351a36eb8c3253 495 SUPERFAMILY SSF47917 374 488 1.41E-45 T 28-03-2018 CFK41_RS07065 f9751a371cd94df987351a36eb8c3253 495 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 158 371 1.5E-64 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CFK41_RS13205 a91347f9121d8ccd3c9e3137fe432a5f 309 Gene3D G3DSA:1.10.3720.10 13 297 9.3E-40 T 28-03-2018 CFK41_RS13205 a91347f9121d8ccd3c9e3137fe432a5f 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 295 1.6E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS13205 a91347f9121d8ccd3c9e3137fe432a5f 309 SUPERFAMILY SSF161098 22 309 4.97E-59 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS12595 672f1d709daece3ae1b282170953b017 566 Pfam PF01384 Phosphate transporter family 91 554 9.7E-114 T 28-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 CFK41_RS16470 bd9ec82fc5ce348cad5633fef75bb602 406 Gene3D G3DSA:3.40.50.720 1 158 2.7E-41 T 28-03-2018 CFK41_RS16470 bd9ec82fc5ce348cad5633fef75bb602 406 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 11 130 8.1E-27 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS16470 bd9ec82fc5ce348cad5633fef75bb602 406 SUPERFAMILY SSF51735 5 172 6.01E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS16470 bd9ec82fc5ce348cad5633fef75bb602 406 Gene3D G3DSA:3.30.360.10 159 396 3.5E-55 T 28-03-2018 CFK41_RS16470 bd9ec82fc5ce348cad5633fef75bb602 406 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 152 221 5.5E-11 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CFK41_RS16470 bd9ec82fc5ce348cad5633fef75bb602 406 SUPERFAMILY SSF55347 146 329 1.8E-39 T 28-03-2018 CFK41_RS11920 a6ed1ecfc21bb97ee534f0457440bfdf 156 Pfam PF00886 Ribosomal protein S16 9 67 1.2E-23 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS11920 a6ed1ecfc21bb97ee534f0457440bfdf 156 SUPERFAMILY SSF54565 2 94 6.15E-33 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS11920 a6ed1ecfc21bb97ee534f0457440bfdf 156 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 23.051 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS11920 a6ed1ecfc21bb97ee534f0457440bfdf 156 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 4.0E-31 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS11920 a6ed1ecfc21bb97ee534f0457440bfdf 156 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 28-03-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS11920 a6ed1ecfc21bb97ee534f0457440bfdf 156 Gene3D G3DSA:3.30.1320.10 2 84 1.3E-30 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS00420 079620809f08b915792a225e4e592b98 545 Gene3D G3DSA:3.20.20.140 36 293 3.0E-15 T 28-03-2018 CFK41_RS00420 079620809f08b915792a225e4e592b98 545 Pfam PF02811 PHP domain 47 129 2.1E-6 T 28-03-2018 IPR004013 PHP domain GO:0003824 CFK41_RS00420 079620809f08b915792a225e4e592b98 545 SMART SM00481 46 122 1.7E-9 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CFK41_RS00420 079620809f08b915792a225e4e592b98 545 SUPERFAMILY SSF89550 264 281 9.29E-20 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CFK41_RS00420 079620809f08b915792a225e4e592b98 545 SUPERFAMILY SSF89550 43 132 9.29E-20 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CFK41_RS00420 079620809f08b915792a225e4e592b98 545 SUPERFAMILY SSF89550 164 223 9.29E-20 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CFK41_RS00235 fab11177784d05a36bb6dda082b6ce91 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 4.9E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CFK41_RS00235 fab11177784d05a36bb6dda082b6ce91 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 4.9E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CFK41_RS00235 fab11177784d05a36bb6dda082b6ce91 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 4.9E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CFK41_RS00235 fab11177784d05a36bb6dda082b6ce91 300 Gene3D G3DSA:1.10.10.10 1 88 6.9E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS00235 fab11177784d05a36bb6dda082b6ce91 300 Gene3D G3DSA:3.40.190.10 184 271 4.5E-12 T 28-03-2018 CFK41_RS00235 fab11177784d05a36bb6dda082b6ce91 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 4.6E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CFK41_RS00235 fab11177784d05a36bb6dda082b6ce91 300 Gene3D G3DSA:3.40.190.10 94 183 2.1E-14 T 28-03-2018 CFK41_RS00235 fab11177784d05a36bb6dda082b6ce91 300 SUPERFAMILY SSF46785 7 116 3.15E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS00235 fab11177784d05a36bb6dda082b6ce91 300 Pfam PF03466 LysR substrate binding domain 94 296 6.6E-31 T 28-03-2018 IPR005119 LysR, substrate-binding CFK41_RS00235 fab11177784d05a36bb6dda082b6ce91 300 SUPERFAMILY SSF53850 95 297 2.58E-29 T 28-03-2018 CFK41_RS13435 461ac12e0eaadce34adbb550775aae82 90 Pfam PF00381 PTS HPr component phosphorylation site 3 83 7.6E-26 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CFK41_RS13435 461ac12e0eaadce34adbb550775aae82 90 Gene3D G3DSA:3.30.1340.10 1 88 2.7E-28 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CFK41_RS13435 461ac12e0eaadce34adbb550775aae82 90 PRINTS PR00107 Phosphocarrier protein signature 13 29 3.4E-12 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CFK41_RS13435 461ac12e0eaadce34adbb550775aae82 90 PRINTS PR00107 Phosphocarrier protein signature 54 71 3.4E-12 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CFK41_RS13435 461ac12e0eaadce34adbb550775aae82 90 PRINTS PR00107 Phosphocarrier protein signature 39 54 3.4E-12 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CFK41_RS13435 461ac12e0eaadce34adbb550775aae82 90 SUPERFAMILY SSF55594 1 87 2.49E-22 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CFK41_RS13435 461ac12e0eaadce34adbb550775aae82 90 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 83 2.2E-26 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CFK41_RS12120 6d55a6756b7dd23c55f882317391799c 889 Gene3D G3DSA:3.30.2070.10 408 449 6.5E-5 T 28-03-2018 CFK41_RS12120 6d55a6756b7dd23c55f882317391799c 889 Pfam PF00384 Molybdopterin oxidoreductase 402 445 4.0E-6 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CFK41_RS12120 6d55a6756b7dd23c55f882317391799c 889 Pfam PF00384 Molybdopterin oxidoreductase 2 376 1.0E-22 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CFK41_RS12120 6d55a6756b7dd23c55f882317391799c 889 Gene3D G3DSA:3.40.228.10 1 274 1.0E-70 T 28-03-2018 CFK41_RS12120 6d55a6756b7dd23c55f882317391799c 889 Gene3D G3DSA:3.40.228.10 541 635 1.0E-14 T 28-03-2018 CFK41_RS12120 6d55a6756b7dd23c55f882317391799c 889 Pfam PF01568 Molydopterin dinucleotide binding domain 691 809 1.1E-10 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CFK41_RS12120 6d55a6756b7dd23c55f882317391799c 889 SUPERFAMILY SSF50692 626 655 4.29E-32 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CFK41_RS12120 6d55a6756b7dd23c55f882317391799c 889 SUPERFAMILY SSF50692 686 816 4.29E-32 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CFK41_RS12120 6d55a6756b7dd23c55f882317391799c 889 SUPERFAMILY SSF53706 2 646 5.1E-196 T 28-03-2018 CFK41_RS12120 6d55a6756b7dd23c55f882317391799c 889 Gene3D G3DSA:2.40.40.20 636 817 7.2E-27 T 28-03-2018 CFK41_RS04555 896a10ec99cbbc08cbad0beef4c58972 488 Gene3D G3DSA:3.40.190.10 252 431 0.013 T 28-03-2018 CFK41_RS04555 896a10ec99cbbc08cbad0beef4c58972 488 Pfam PF01547 Bacterial extracellular solute-binding protein 92 391 1.2E-21 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CFK41_RS04555 896a10ec99cbbc08cbad0beef4c58972 488 Gene3D G3DSA:3.40.190.10 67 242 2.1E-26 T 28-03-2018 CFK41_RS04555 896a10ec99cbbc08cbad0beef4c58972 488 TIGRFAM TIGR03851 chitin_NgcE: carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding protein 31 485 5.3E-191 T 28-03-2018 IPR022386 Carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding protein CFK41_RS04555 896a10ec99cbbc08cbad0beef4c58972 488 SUPERFAMILY SSF53850 76 476 6.86E-44 T 28-03-2018 CFK41_RS04715 b7ffefd5a69533126cb6ca3f136b30ca 134 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 15 131 8.4E-57 T 28-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS04715 b7ffefd5a69533126cb6ca3f136b30ca 134 PIRSF PIRSF002131 2 134 3.2E-52 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CFK41_RS04715 b7ffefd5a69533126cb6ca3f136b30ca 134 SUPERFAMILY SSF53137 19 134 1.77E-47 T 28-03-2018 CFK41_RS04715 b7ffefd5a69533126cb6ca3f136b30ca 134 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 6 134 32.632 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CFK41_RS04715 b7ffefd5a69533126cb6ca3f136b30ca 134 Gene3D G3DSA:3.30.420.80 8 134 2.0E-44 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CFK41_RS04715 b7ffefd5a69533126cb6ca3f136b30ca 134 ProSitePatterns PS00054 Ribosomal protein S11 signature. 102 124 - T 28-03-2018 IPR018102 Ribosomal S11, conserved site CFK41_RS04715 b7ffefd5a69533126cb6ca3f136b30ca 134 Pfam PF00411 Ribosomal protein S11 24 133 9.9E-47 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CFK41_RS12530 30d405ef82372f9b8d119df04a6671aa 699 Pfam PF01515 Phosphate acetyl/butaryl transferase 371 686 5.3E-131 T 28-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CFK41_RS12530 30d405ef82372f9b8d119df04a6671aa 699 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 385 686 3.9E-127 T 28-03-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CFK41_RS12530 30d405ef82372f9b8d119df04a6671aa 699 SUPERFAMILY SSF52540 8 212 2.34E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS12530 30d405ef82372f9b8d119df04a6671aa 699 PIRSF PIRSF006107 5 192 7.6E-12 T 28-03-2018 IPR016475 Phosphate acetyltransferase, bacteria GO:0008959 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CFK41_RS12530 30d405ef82372f9b8d119df04a6671aa 699 PIRSF PIRSF006107 181 694 1.8E-173 T 28-03-2018 IPR016475 Phosphate acetyltransferase, bacteria GO:0008959 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CFK41_RS12530 30d405ef82372f9b8d119df04a6671aa 699 Gene3D G3DSA:3.40.50.300 4 207 2.7E-26 T 28-03-2018 CFK41_RS12530 30d405ef82372f9b8d119df04a6671aa 699 Pfam PF07085 DRTGG domain 211 323 1.8E-20 T 28-03-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CFK41_RS12530 30d405ef82372f9b8d119df04a6671aa 699 Gene3D G3DSA:3.40.718.10 387 665 1.5E-67 T 28-03-2018 CFK41_RS12530 30d405ef82372f9b8d119df04a6671aa 699 Pfam PF13500 AAA domain 7 206 3.6E-20 T 28-03-2018 CFK41_RS12530 30d405ef82372f9b8d119df04a6671aa 699 SUPERFAMILY SSF75138 206 327 1.07E-20 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CFK41_RS12530 30d405ef82372f9b8d119df04a6671aa 699 SUPERFAMILY SSF53659 368 689 1.56E-97 T 28-03-2018 CFK41_RS12530 30d405ef82372f9b8d119df04a6671aa 699 Gene3D G3DSA:3.40.1390.20 208 346 4.2E-24 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CFK41_RS00310 ebb1a19f4a2beedf8c52a7b54a6e2770 177 SUPERFAMILY SSF52540 5 122 1.8E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS00310 ebb1a19f4a2beedf8c52a7b54a6e2770 177 Pfam PF13671 AAA domain 5 143 2.5E-22 T 28-03-2018 CFK41_RS00310 ebb1a19f4a2beedf8c52a7b54a6e2770 177 Gene3D G3DSA:3.40.50.300 2 149 1.5E-16 T 28-03-2018 CFK41_RS08195 893aa217f2d9cba410f2dfbbef029cd1 328 Gene3D G3DSA:3.30.300.20 217 328 2.7E-38 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CFK41_RS08195 893aa217f2d9cba410f2dfbbef029cd1 328 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 25 188 6.4E-21 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CFK41_RS08195 893aa217f2d9cba410f2dfbbef029cd1 328 Gene3D G3DSA:3.40.50.300 40 216 1.0E-31 T 28-03-2018 CFK41_RS08195 893aa217f2d9cba410f2dfbbef029cd1 328 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 102 117 1.0E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CFK41_RS08195 893aa217f2d9cba410f2dfbbef029cd1 328 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 46 1.0E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CFK41_RS08195 893aa217f2d9cba410f2dfbbef029cd1 328 Gene3D G3DSA:3.40.50.300 17 39 0.0031 T 28-03-2018 CFK41_RS08195 893aa217f2d9cba410f2dfbbef029cd1 328 SUPERFAMILY SSF52540 26 234 5.47E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS08195 893aa217f2d9cba410f2dfbbef029cd1 328 Hamap MF_00367 GTPase Era [era]. 21 328 34.557 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS08195 893aa217f2d9cba410f2dfbbef029cd1 328 TIGRFAM TIGR00436 era: GTP-binding protein Era 24 311 2.8E-71 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS08195 893aa217f2d9cba410f2dfbbef029cd1 328 Pfam PF01926 50S ribosome-binding GTPase 26 129 4.9E-21 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CFK41_RS08195 893aa217f2d9cba410f2dfbbef029cd1 328 SUPERFAMILY SSF54814 201 328 2.25E-32 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CFK41_RS08195 893aa217f2d9cba410f2dfbbef029cd1 328 Pfam PF07650 KH domain 252 317 1.0E-16 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS08510 2f0f2c20691007337ab9a6f389d6b5df 340 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 24 60 8.4E-8 T 28-03-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CFK41_RS08510 2f0f2c20691007337ab9a6f389d6b5df 340 PIRSF PIRSF005963 4 319 2.1E-119 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CFK41_RS08510 2f0f2c20691007337ab9a6f389d6b5df 340 SUPERFAMILY SSF102114 42 309 3.66E-57 T 28-03-2018 CFK41_RS08510 2f0f2c20691007337ab9a6f389d6b5df 340 Pfam PF04055 Radical SAM superfamily 80 235 4.3E-11 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CFK41_RS08510 2f0f2c20691007337ab9a6f389d6b5df 340 SMART SM00729 71 276 4.8E-11 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CFK41_RS08510 2f0f2c20691007337ab9a6f389d6b5df 340 Hamap MF_00206 Lipoyl synthase [lipA]. 1 309 130.737 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CFK41_RS08510 2f0f2c20691007337ab9a6f389d6b5df 340 Gene3D G3DSA:3.80.30.20 68 281 1.4E-21 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CFK41_RS08510 2f0f2c20691007337ab9a6f389d6b5df 340 TIGRFAM TIGR00510 lipA: lipoyl synthase 21 305 2.0E-99 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CFK41_RS00840 1e40e53fb3e0227475c7dbef194327c6 1156 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 667 1150 35.1 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CFK41_RS00840 1e40e53fb3e0227475c7dbef194327c6 1156 Pfam PF00152 tRNA synthetases class II (D, K and N) 807 1147 1.3E-64 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS00840 1e40e53fb3e0227475c7dbef194327c6 1156 Gene3D G3DSA:3.40.630.30 316 586 3.8E-4 T 28-03-2018 CFK41_RS00840 1e40e53fb3e0227475c7dbef194327c6 1156 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 285 589 4.3E-86 T 28-03-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal CFK41_RS00840 1e40e53fb3e0227475c7dbef194327c6 1156 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 663 1149 3.6E-139 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CFK41_RS00840 1e40e53fb3e0227475c7dbef194327c6 1156 PRINTS PR00982 Lysyl-tRNA synthetase signature 1033 1049 1.2E-28 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CFK41_RS00840 1e40e53fb3e0227475c7dbef194327c6 1156 PRINTS PR00982 Lysyl-tRNA synthetase signature 887 900 1.2E-28 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CFK41_RS00840 1e40e53fb3e0227475c7dbef194327c6 1156 PRINTS PR00982 Lysyl-tRNA synthetase signature 842 852 1.2E-28 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CFK41_RS00840 1e40e53fb3e0227475c7dbef194327c6 1156 PRINTS PR00982 Lysyl-tRNA synthetase signature 905 922 1.2E-28 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CFK41_RS00840 1e40e53fb3e0227475c7dbef194327c6 1156 PRINTS PR00982 Lysyl-tRNA synthetase signature 858 874 1.2E-28 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CFK41_RS00840 1e40e53fb3e0227475c7dbef194327c6 1156 Pfam PF01336 OB-fold nucleic acid binding domain 713 783 3.6E-12 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CFK41_RS00840 1e40e53fb3e0227475c7dbef194327c6 1156 SUPERFAMILY SSF55681 805 1148 1.88E-89 T 28-03-2018 CFK41_RS00840 1e40e53fb3e0227475c7dbef194327c6 1156 SUPERFAMILY SSF50249 660 798 8.14E-31 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS00840 1e40e53fb3e0227475c7dbef194327c6 1156 Gene3D G3DSA:2.40.50.140 661 798 6.8E-33 T 28-03-2018 CFK41_RS00840 1e40e53fb3e0227475c7dbef194327c6 1156 Gene3D G3DSA:3.30.930.10 799 1147 2.0E-77 T 28-03-2018 CFK41_RS00840 1e40e53fb3e0227475c7dbef194327c6 1156 Pfam PF16995 Transmembrane region of lysyl-tRNA synthetase 43 267 4.6E-21 T 28-03-2018 IPR031553 Lysyl-tRNA synthetase, N-terminal transmembrane region KEGG: 00970+6.1.1.6 CFK41_RS13975 da07d16af6eda77a82260725152dbfa7 297 Gene3D G3DSA:2.115.10.20 163 296 3.3E-18 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CFK41_RS13975 da07d16af6eda77a82260725152dbfa7 297 SUPERFAMILY SSF75005 31 252 4.71E-32 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CFK41_RS13975 da07d16af6eda77a82260725152dbfa7 297 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 36 204 1.7E-12 T 28-03-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal CFK41_RS13975 da07d16af6eda77a82260725152dbfa7 297 Gene3D G3DSA:2.115.10.20 30 162 6.5E-24 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CFK41_RS03800 9a84df0c92ac5aa77280b05f4132daa8 450 SUPERFAMILY SSF103473 18 439 1.2E-34 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS03800 9a84df0c92ac5aa77280b05f4132daa8 450 Pfam PF11700 Vacuole effluxer Atg22 like 77 439 2.1E-28 T 28-03-2018 IPR024671 Autophagy-related protein 22-like CFK41_RS03800 9a84df0c92ac5aa77280b05f4132daa8 450 Gene3D G3DSA:1.20.1250.20 22 242 1.4E-11 T 28-03-2018 CFK41_RS03800 9a84df0c92ac5aa77280b05f4132daa8 450 Gene3D G3DSA:1.20.1250.20 247 439 2.6E-18 T 28-03-2018 CFK41_RS10155 b08efa6af6d45d5904adda5abdf123ba 387 SUPERFAMILY SSF53383 28 382 4.59E-66 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS10155 b08efa6af6d45d5904adda5abdf123ba 387 PIRSF PIRSF000525 14 385 1.8E-74 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CFK41_RS10155 b08efa6af6d45d5904adda5abdf123ba 387 Gene3D G3DSA:3.90.1150.10 272 385 1.6E-22 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS10155 b08efa6af6d45d5904adda5abdf123ba 387 Pfam PF00266 Aminotransferase class-V 37 343 1.0E-11 T 28-03-2018 IPR000192 Aminotransferase class V domain CFK41_RS10155 b08efa6af6d45d5904adda5abdf123ba 387 TIGRFAM TIGR01366 serC_3: putative phosphoserine aminotransferase 23 383 9.2E-169 T 28-03-2018 IPR006272 Phosphoserine aminotransferase, Mycobacterial-type GO:0004648|GO:0006564|GO:0009058 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52 CFK41_RS10155 b08efa6af6d45d5904adda5abdf123ba 387 Gene3D G3DSA:3.40.640.10 33 271 2.5E-19 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS14185 21dc1b03a4d3ab6b2266eb096d1d3d77 244 Gene3D G3DSA:1.10.10.10 7 80 1.6E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS14185 21dc1b03a4d3ab6b2266eb096d1d3d77 244 Gene3D G3DSA:1.20.120.530 81 229 2.6E-29 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS14185 21dc1b03a4d3ab6b2266eb096d1d3d77 244 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 78 1.3E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS14185 21dc1b03a4d3ab6b2266eb096d1d3d77 244 SUPERFAMILY SSF48008 84 219 1.2E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS14185 21dc1b03a4d3ab6b2266eb096d1d3d77 244 Pfam PF07729 FCD domain 88 210 1.6E-23 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS14185 21dc1b03a4d3ab6b2266eb096d1d3d77 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 68 5.1E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS14185 21dc1b03a4d3ab6b2266eb096d1d3d77 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 52 5.1E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS14185 21dc1b03a4d3ab6b2266eb096d1d3d77 244 SMART SM00895 88 212 2.1E-17 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS14185 21dc1b03a4d3ab6b2266eb096d1d3d77 244 SMART SM00345 20 78 3.2E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS14185 21dc1b03a4d3ab6b2266eb096d1d3d77 244 SUPERFAMILY SSF46785 15 102 2.6E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS01170 6f732f4c28ab83916c009df963664605 451 Gene3D G3DSA:3.40.190.10 228 399 2.2E-9 T 28-03-2018 CFK41_RS01170 6f732f4c28ab83916c009df963664605 451 SUPERFAMILY SSF53850 62 438 3.16E-65 T 28-03-2018 CFK41_RS01170 6f732f4c28ab83916c009df963664605 451 Gene3D G3DSA:3.40.190.10 47 227 3.8E-33 T 28-03-2018 CFK41_RS01170 6f732f4c28ab83916c009df963664605 451 Pfam PF13416 Bacterial extracellular solute-binding protein 80 388 1.3E-41 T 28-03-2018 CFK41_RS02745 4304cca0af8fdbe0f842cf72b1bd3271 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 179 197 4.7E-14 T 28-03-2018 CFK41_RS02745 4304cca0af8fdbe0f842cf72b1bd3271 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 301 323 4.7E-14 T 28-03-2018 CFK41_RS02745 4304cca0af8fdbe0f842cf72b1bd3271 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 121 139 4.7E-14 T 28-03-2018 CFK41_RS02745 4304cca0af8fdbe0f842cf72b1bd3271 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 25 44 4.7E-14 T 28-03-2018 CFK41_RS02745 4304cca0af8fdbe0f842cf72b1bd3271 483 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 24 46 1.4E-6 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CFK41_RS02745 4304cca0af8fdbe0f842cf72b1bd3271 483 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 311 329 1.4E-6 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CFK41_RS02745 4304cca0af8fdbe0f842cf72b1bd3271 483 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 175 199 1.4E-6 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CFK41_RS02745 4304cca0af8fdbe0f842cf72b1bd3271 483 Gene3D G3DSA:3.50.50.60 150 350 7.0E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS02745 4304cca0af8fdbe0f842cf72b1bd3271 483 SUPERFAMILY SSF51905 24 354 2.52E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS02745 4304cca0af8fdbe0f842cf72b1bd3271 483 Gene3D G3DSA:3.50.50.60 23 149 2.5E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS02745 4304cca0af8fdbe0f842cf72b1bd3271 483 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 24 340 1.6E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS10255 3e34cfe5679d88ca6760a23d5d5db952 308 Pfam PF08544 GHMP kinases C terminal 212 281 3.1E-12 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CFK41_RS10255 3e34cfe5679d88ca6760a23d5d5db952 308 Gene3D G3DSA:3.30.230.10 8 165 4.9E-42 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CFK41_RS10255 3e34cfe5679d88ca6760a23d5d5db952 308 SUPERFAMILY SSF54211 8 161 1.21E-39 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CFK41_RS10255 3e34cfe5679d88ca6760a23d5d5db952 308 Gene3D G3DSA:3.30.70.890 166 297 5.6E-31 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CFK41_RS10255 3e34cfe5679d88ca6760a23d5d5db952 308 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 8 290 29.975 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CFK41_RS10255 3e34cfe5679d88ca6760a23d5d5db952 308 SUPERFAMILY SSF55060 168 283 4.32E-24 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CFK41_RS10255 3e34cfe5679d88ca6760a23d5d5db952 308 PIRSF PIRSF010376 6 305 5.9E-74 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CFK41_RS10255 3e34cfe5679d88ca6760a23d5d5db952 308 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 6 281 7.0E-56 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CFK41_RS10255 3e34cfe5679d88ca6760a23d5d5db952 308 Pfam PF00288 GHMP kinases N terminal domain 93 149 1.4E-10 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CFK41_RS15175 6120bfd22b416d15f604fac227e8b0f2 624 SUPERFAMILY SSF48208 236 617 1.12E-94 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CFK41_RS15175 6120bfd22b416d15f604fac227e8b0f2 624 Pfam PF00723 Glycosyl hydrolases family 15 255 568 1.2E-52 T 28-03-2018 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 CFK41_RS15175 6120bfd22b416d15f604fac227e8b0f2 624 Gene3D G3DSA:1.50.10.10 223 578 7.3E-90 T 28-03-2018 CFK41_RS09460 25ec2e2737a608a747fe2eb134dfe6c9 277 SUPERFAMILY SSF51366 16 259 6.97E-73 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CFK41_RS09460 25ec2e2737a608a747fe2eb134dfe6c9 277 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 57 74 - T 28-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 CFK41_RS09460 25ec2e2737a608a747fe2eb134dfe6c9 277 Gene3D G3DSA:3.20.20.70 15 266 8.8E-62 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS09460 25ec2e2737a608a747fe2eb134dfe6c9 277 Pfam PF00218 Indole-3-glycerol phosphate synthase 8 259 2.2E-76 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CFK41_RS09460 25ec2e2737a608a747fe2eb134dfe6c9 277 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 6 263 32.532 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CFK41_RS03815 a23a3803356db185e7abe064e8f6c40a 526 Pfam PF00361 Proton-conducting membrane transporter 132 420 1.2E-65 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CFK41_RS03815 a23a3803356db185e7abe064e8f6c40a 526 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 325 344 7.8E-14 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CFK41_RS03815 a23a3803356db185e7abe064e8f6c40a 526 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 377 403 7.8E-14 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CFK41_RS03815 a23a3803356db185e7abe064e8f6c40a 526 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 239 263 7.8E-14 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CFK41_RS03815 a23a3803356db185e7abe064e8f6c40a 526 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 138 157 7.8E-14 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CFK41_RS03815 a23a3803356db185e7abe064e8f6c40a 526 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 168 192 7.8E-14 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CFK41_RS17215 50740c8f540f76a41c32a6f47f5099f9 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 9.9E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17215 50740c8f540f76a41c32a6f47f5099f9 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 9.9E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17215 50740c8f540f76a41c32a6f47f5099f9 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 9.9E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17215 50740c8f540f76a41c32a6f47f5099f9 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 9.9E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17215 50740c8f540f76a41c32a6f47f5099f9 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 9.9E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17215 50740c8f540f76a41c32a6f47f5099f9 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 9.9E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17215 50740c8f540f76a41c32a6f47f5099f9 256 Gene3D G3DSA:3.40.50.10090 2 52 1.5E-7 T 28-03-2018 CFK41_RS17215 50740c8f540f76a41c32a6f47f5099f9 256 SUPERFAMILY SSF51735 8 255 3.56E-73 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS17215 50740c8f540f76a41c32a6f47f5099f9 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 194 0.0033 T 28-03-2018 CFK41_RS17215 50740c8f540f76a41c32a6f47f5099f9 256 Gene3D G3DSA:3.40.50.720 53 256 8.8E-57 T 28-03-2018 CFK41_RS17215 50740c8f540f76a41c32a6f47f5099f9 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 3.3E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17215 50740c8f540f76a41c32a6f47f5099f9 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 3.3E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17215 50740c8f540f76a41c32a6f47f5099f9 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 3.3E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17215 50740c8f540f76a41c32a6f47f5099f9 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 252 2.9E-60 T 28-03-2018 CFK41_RS17215 50740c8f540f76a41c32a6f47f5099f9 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CFK41_RS13460 c663d8ba40c60c882c19fe12935acd76 328 SMART SM00829 9 310 3.0E-26 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CFK41_RS13460 c663d8ba40c60c882c19fe12935acd76 328 Pfam PF00107 Zinc-binding dehydrogenase 141 255 7.8E-26 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CFK41_RS13460 c663d8ba40c60c882c19fe12935acd76 328 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 3 312 4.9E-109 T 28-03-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 CFK41_RS13460 c663d8ba40c60c882c19fe12935acd76 328 Gene3D G3DSA:3.40.50.720 133 243 4.8E-25 T 28-03-2018 CFK41_RS13460 c663d8ba40c60c882c19fe12935acd76 328 Gene3D G3DSA:3.90.180.10 1 132 3.0E-29 T 28-03-2018 CFK41_RS13460 c663d8ba40c60c882c19fe12935acd76 328 SUPERFAMILY SSF50129 3 127 5.17E-27 T 28-03-2018 IPR011032 GroES-like CFK41_RS13460 c663d8ba40c60c882c19fe12935acd76 328 SUPERFAMILY SSF51735 101 271 1.73E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS13460 c663d8ba40c60c882c19fe12935acd76 328 Gene3D G3DSA:3.90.180.10 244 314 3.9E-6 T 28-03-2018 CFK41_RS03050 7c636e618c2d881bc65da900aaa966a4 372 SUPERFAMILY SSF53756 2 365 1.38E-80 T 28-03-2018 CFK41_RS03050 7c636e618c2d881bc65da900aaa966a4 372 Gene3D G3DSA:3.40.50.2000 2 188 1.2E-20 T 28-03-2018 CFK41_RS03050 7c636e618c2d881bc65da900aaa966a4 372 Gene3D G3DSA:3.40.50.2000 189 350 1.5E-38 T 28-03-2018 CFK41_RS03050 7c636e618c2d881bc65da900aaa966a4 372 Pfam PF13439 Glycosyltransferase Family 4 15 178 1.6E-25 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CFK41_RS03050 7c636e618c2d881bc65da900aaa966a4 372 Pfam PF00534 Glycosyl transferases group 1 198 345 4.0E-28 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CFK41_RS09060 8636591245c54471f62168db65f2cf21 238 Pfam PF00005 ABC transporter 20 159 3.4E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS09060 8636591245c54471f62168db65f2cf21 238 Gene3D G3DSA:3.40.50.300 1 235 5.1E-58 T 28-03-2018 CFK41_RS09060 8636591245c54471f62168db65f2cf21 238 SUPERFAMILY SSF52540 3 220 1.94E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS09060 8636591245c54471f62168db65f2cf21 238 SMART SM00382 29 207 1.5E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS06570 afb6d850ca7e8a821fd6e997db21b11b 620 Pfam PF00005 ABC transporter 376 537 6.1E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS06570 afb6d850ca7e8a821fd6e997db21b11b 620 SMART SM00382 384 587 3.6E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS06570 afb6d850ca7e8a821fd6e997db21b11b 620 ProSitePatterns PS00211 ABC transporters family signature. 510 524 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS06570 afb6d850ca7e8a821fd6e997db21b11b 620 Gene3D G3DSA:1.10.3720.10 12 265 8.1E-35 T 28-03-2018 CFK41_RS06570 afb6d850ca7e8a821fd6e997db21b11b 620 Gene3D G3DSA:3.40.50.300 352 617 2.1E-65 T 28-03-2018 CFK41_RS06570 afb6d850ca7e8a821fd6e997db21b11b 620 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 276 2.5E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS06570 afb6d850ca7e8a821fd6e997db21b11b 620 SUPERFAMILY SSF161098 68 247 4.32E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS06570 afb6d850ca7e8a821fd6e997db21b11b 620 SUPERFAMILY SSF52540 355 609 2.56E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS01545 d37da7911624a718b234288026276c19 280 Pfam PF06724 Domain of Unknown Function (DUF1206) 34 101 1.1E-16 T 28-03-2018 IPR009597 Domain of unknown function DUF1206 CFK41_RS01545 d37da7911624a718b234288026276c19 280 Pfam PF06724 Domain of Unknown Function (DUF1206) 119 184 1.6E-12 T 28-03-2018 IPR009597 Domain of unknown function DUF1206 CFK41_RS01545 d37da7911624a718b234288026276c19 280 Pfam PF06724 Domain of Unknown Function (DUF1206) 209 277 1.9E-13 T 28-03-2018 IPR009597 Domain of unknown function DUF1206 CFK41_RS01545 d37da7911624a718b234288026276c19 280 Gene3D G3DSA:1.20.1300.10 2 245 2.3E-5 T 28-03-2018 CFK41_RS12230 f3c24ff376e2b0ef5f3e994fe883d525 848 SUPERFAMILY SSF74650 15 294 1.48E-59 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CFK41_RS12230 f3c24ff376e2b0ef5f3e994fe883d525 848 PIRSF PIRSF036289 12 795 5.9E-194 T 28-03-2018 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase CFK41_RS12230 f3c24ff376e2b0ef5f3e994fe883d525 848 Gene3D G3DSA:2.60.420.10 717 787 1.5E-23 T 28-03-2018 CFK41_RS12230 f3c24ff376e2b0ef5f3e994fe883d525 848 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 32 293 4.0E-58 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 CFK41_RS12230 f3c24ff376e2b0ef5f3e994fe883d525 848 Gene3D G3DSA:1.50.10.10 343 716 4.4E-105 T 28-03-2018 CFK41_RS12230 f3c24ff376e2b0ef5f3e994fe883d525 848 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 349 730 5.8E-122 T 28-03-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 CFK41_RS12230 f3c24ff376e2b0ef5f3e994fe883d525 848 Gene3D G3DSA:2.70.98.40 13 296 6.2E-77 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 CFK41_RS12230 f3c24ff376e2b0ef5f3e994fe883d525 848 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 734 784 9.9E-16 T 28-03-2018 IPR005194 Glycoside hydrolase family 65, C-terminal CFK41_RS12230 f3c24ff376e2b0ef5f3e994fe883d525 848 SUPERFAMILY SSF48208 299 781 1.25E-117 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CFK41_RS01775 293a28f6c8894291d083035cdfddb880 191 Pfam PF01872 RibD C-terminal domain 5 183 2.3E-25 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CFK41_RS01775 293a28f6c8894291d083035cdfddb880 191 SUPERFAMILY SSF53597 4 190 1.44E-22 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CFK41_RS01775 293a28f6c8894291d083035cdfddb880 191 Gene3D G3DSA:3.40.430.10 4 189 2.5E-28 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CFK41_RS13000 8a7d4802f6937f29a53d9bba0c3f1117 154 Gene3D G3DSA:3.40.250.10 18 153 6.9E-21 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS13000 8a7d4802f6937f29a53d9bba0c3f1117 154 SMART SM00450 40 144 1.7E-12 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS13000 8a7d4802f6937f29a53d9bba0c3f1117 154 SUPERFAMILY SSF52821 26 146 1.57E-20 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS13000 8a7d4802f6937f29a53d9bba0c3f1117 154 Pfam PF00581 Rhodanese-like domain 42 138 1.8E-7 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS12620 ae0a7dad475c1cf2c1702e99b1d6fc07 98 Gene3D G3DSA:2.30.33.40 1 97 2.2E-39 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CFK41_RS12620 ae0a7dad475c1cf2c1702e99b1d6fc07 98 Hamap MF_00580 10 kDa chaperonin [groS]. 4 97 26.482 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CFK41_RS12620 ae0a7dad475c1cf2c1702e99b1d6fc07 98 ProSitePatterns PS00681 Chaperonins cpn10 signature. 5 29 - T 28-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 CFK41_RS12620 ae0a7dad475c1cf2c1702e99b1d6fc07 98 SMART SM00883 4 96 4.7E-55 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CFK41_RS12620 ae0a7dad475c1cf2c1702e99b1d6fc07 98 Pfam PF00166 Chaperonin 10 Kd subunit 5 96 1.9E-35 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CFK41_RS12620 ae0a7dad475c1cf2c1702e99b1d6fc07 98 PRINTS PR00297 10kDa chaperonin signature 83 96 3.2E-32 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CFK41_RS12620 ae0a7dad475c1cf2c1702e99b1d6fc07 98 PRINTS PR00297 10kDa chaperonin signature 62 74 3.2E-32 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CFK41_RS12620 ae0a7dad475c1cf2c1702e99b1d6fc07 98 PRINTS PR00297 10kDa chaperonin signature 5 20 3.2E-32 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CFK41_RS12620 ae0a7dad475c1cf2c1702e99b1d6fc07 98 PRINTS PR00297 10kDa chaperonin signature 27 48 3.2E-32 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CFK41_RS12620 ae0a7dad475c1cf2c1702e99b1d6fc07 98 SUPERFAMILY SSF50129 3 97 5.65E-35 T 28-03-2018 IPR011032 GroES-like CFK41_RS16860 75d33c82a49806eb7bc2297a801bd556 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 278 8.8E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS16860 75d33c82a49806eb7bc2297a801bd556 287 Gene3D G3DSA:1.10.3720.10 7 287 2.5E-46 T 28-03-2018 CFK41_RS16860 75d33c82a49806eb7bc2297a801bd556 287 SUPERFAMILY SSF161098 49 275 5.49E-55 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS14695 966a65f0530996d91529e83fc1f8aed9 221 Pfam PF07729 FCD domain 83 206 1.1E-20 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS14695 966a65f0530996d91529e83fc1f8aed9 221 SUPERFAMILY SSF46785 11 77 7.54E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS14695 966a65f0530996d91529e83fc1f8aed9 221 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 65 1.3E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS14695 966a65f0530996d91529e83fc1f8aed9 221 SMART SM00895 83 207 2.5E-15 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS14695 966a65f0530996d91529e83fc1f8aed9 221 Gene3D G3DSA:1.20.120.530 77 221 2.3E-29 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS14695 966a65f0530996d91529e83fc1f8aed9 221 SMART SM00345 16 73 9.8E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS14695 966a65f0530996d91529e83fc1f8aed9 221 SUPERFAMILY SSF48008 80 212 3.14E-24 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS14695 966a65f0530996d91529e83fc1f8aed9 221 Gene3D G3DSA:1.10.10.10 5 76 4.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS03770 caec2316d6bf8d9f8687669b3fb7362b 677 SUPERFAMILY SSF52833 25 159 1.22E-28 T 28-03-2018 IPR012336 Thioredoxin-like fold CFK41_RS03770 caec2316d6bf8d9f8687669b3fb7362b 677 Gene3D G3DSA:2.120.10.30 171 418 1.1E-14 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CFK41_RS03770 caec2316d6bf8d9f8687669b3fb7362b 677 SUPERFAMILY SSF101898 176 222 8.11E-23 T 28-03-2018 CFK41_RS03770 caec2316d6bf8d9f8687669b3fb7362b 677 SUPERFAMILY SSF101898 314 542 8.11E-23 T 28-03-2018 CFK41_RS03770 caec2316d6bf8d9f8687669b3fb7362b 677 Gene3D G3DSA:2.130.10.10 419 567 0.011 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CFK41_RS03770 caec2316d6bf8d9f8687669b3fb7362b 677 Pfam PF01436 NHL repeat 181 208 5.7E-5 T 28-03-2018 IPR001258 NHL repeat GO:0005515 CFK41_RS03770 caec2316d6bf8d9f8687669b3fb7362b 677 Pfam PF13905 Thioredoxin-like 40 134 1.4E-8 T 28-03-2018 IPR012336 Thioredoxin-like fold CFK41_RS03770 caec2316d6bf8d9f8687669b3fb7362b 677 Gene3D G3DSA:3.40.30.10 7 158 3.5E-21 T 28-03-2018 CFK41_RS11915 aa271ada5a4feef2b6a2602097c56dc9 80 SUPERFAMILY SSF54814 19 64 4.8E-6 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CFK41_RS11915 aa271ada5a4feef2b6a2602097c56dc9 80 Hamap MF_00088 UPF0109 protein . 4 75 19.107 T 28-03-2018 IPR020627 Uncharacterised protein family UPF0109 CFK41_RS11915 aa271ada5a4feef2b6a2602097c56dc9 80 Pfam PF13083 KH domain 6 67 1.3E-16 T 28-03-2018 CFK41_RS11915 aa271ada5a4feef2b6a2602097c56dc9 80 Gene3D G3DSA:3.30.300.20 1 78 2.3E-11 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CFK41_RS08185 c9af2bd1379ae765dfe991fa69420b91 153 SUPERFAMILY SSF55486 5 146 1.07E-38 T 28-03-2018 CFK41_RS08185 c9af2bd1379ae765dfe991fa69420b91 153 Gene3D G3DSA:3.40.390.30 2 153 4.0E-43 T 28-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 CFK41_RS08185 c9af2bd1379ae765dfe991fa69420b91 153 Pfam PF02130 Uncharacterized protein family UPF0054 20 144 1.7E-36 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CFK41_RS08185 c9af2bd1379ae765dfe991fa69420b91 153 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 36 144 1.1E-32 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CFK41_RS08185 c9af2bd1379ae765dfe991fa69420b91 153 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 116 126 - T 28-03-2018 IPR020549 Endoribonuclease YbeY, conserved site CFK41_RS08185 c9af2bd1379ae765dfe991fa69420b91 153 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 152 21.4 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CFK41_RS04865 a12952f2b630aaa10c79804667149c63 304 Gene3D G3DSA:3.30.470.20 117 253 5.6E-49 T 28-03-2018 CFK41_RS04865 a12952f2b630aaa10c79804667149c63 304 Gene3D G3DSA:3.30.200.20 14 116 1.5E-31 T 28-03-2018 CFK41_RS04865 a12952f2b630aaa10c79804667149c63 304 SUPERFAMILY SSF56104 14 304 1.01E-89 T 28-03-2018 CFK41_RS04865 a12952f2b630aaa10c79804667149c63 304 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 17 301 22.718 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CFK41_RS04865 a12952f2b630aaa10c79804667149c63 304 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 20 301 2.2E-65 T 28-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 CFK41_RS04865 a12952f2b630aaa10c79804667149c63 304 ProSitePatterns PS01058 SAICAR synthetase signature 2. 208 216 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CFK41_RS04865 a12952f2b630aaa10c79804667149c63 304 Pfam PF01259 SAICAR synthetase 20 272 1.9E-92 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CFK41_RS14635 6af98b8ae2fb399b12d141fbf80df6f5 153 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 15 128 1.1E-9 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CFK41_RS14635 6af98b8ae2fb399b12d141fbf80df6f5 153 Gene3D G3DSA:3.10.180.10 4 142 1.4E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS14635 6af98b8ae2fb399b12d141fbf80df6f5 153 SUPERFAMILY SSF54593 13 134 9.53E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS00115 253fe5fab9b19d6aa36c827114d9e279 869 Pfam PF17390 Bacterial alpha-L-rhamnosidase C-terminal domain 794 852 3.3E-10 T 28-03-2018 IPR035398 Alpha-L-rhamnosidase C-terminal domain CFK41_RS00115 253fe5fab9b19d6aa36c827114d9e279 869 Gene3D G3DSA:2.60.120.260 155 356 8.6E-21 T 28-03-2018 IPR008979 Galactose-binding domain-like CFK41_RS00115 253fe5fab9b19d6aa36c827114d9e279 869 Gene3D G3DSA:1.50.10.10 468 788 1.2E-32 T 28-03-2018 CFK41_RS00115 253fe5fab9b19d6aa36c827114d9e279 869 SUPERFAMILY SSF48208 544 853 2.65E-31 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CFK41_RS00115 253fe5fab9b19d6aa36c827114d9e279 869 SUPERFAMILY SSF49265 67 155 4.74E-5 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CFK41_RS00115 253fe5fab9b19d6aa36c827114d9e279 869 Pfam PF05592 Bacterial alpha-L-rhamnosidase concanavalin-like domain 369 451 4.9E-5 T 28-03-2018 IPR008902 Alpha-L-rhamnosidase, concanavalin-like domain CFK41_RS00115 253fe5fab9b19d6aa36c827114d9e279 869 Gene3D G3DSA:2.60.420.10 789 861 4.2E-16 T 28-03-2018 CFK41_RS00115 253fe5fab9b19d6aa36c827114d9e279 869 Pfam PF17389 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain 537 786 1.0E-24 T 28-03-2018 IPR035396 Alpha-L-rhamnosidase, six-hairpin glycosidase domain CFK41_RS00115 253fe5fab9b19d6aa36c827114d9e279 869 Pfam PF17389 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain 470 527 2.9E-8 T 28-03-2018 IPR035396 Alpha-L-rhamnosidase, six-hairpin glycosidase domain CFK41_RS00115 253fe5fab9b19d6aa36c827114d9e279 869 Gene3D G3DSA:2.60.120.260 361 467 1.6E-9 T 28-03-2018 IPR008979 Galactose-binding domain-like CFK41_RS00115 253fe5fab9b19d6aa36c827114d9e279 869 Gene3D G3DSA:2.60.40.10 50 154 5.7E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS02855 26505385595e2c207af95d795e731312 630 Gene3D G3DSA:1.20.1560.10 26 362 2.1E-49 T 28-03-2018 CFK41_RS02855 26505385595e2c207af95d795e731312 630 Pfam PF00005 ABC transporter 403 552 2.7E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS02855 26505385595e2c207af95d795e731312 630 Pfam PF00664 ABC transporter transmembrane region 44 326 1.1E-26 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS02855 26505385595e2c207af95d795e731312 630 SMART SM00382 412 598 4.6E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS02855 26505385595e2c207af95d795e731312 630 SUPERFAMILY SSF90123 39 359 1.02E-56 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS02855 26505385595e2c207af95d795e731312 630 Gene3D G3DSA:3.40.50.300 382 627 9.5E-65 T 28-03-2018 CFK41_RS02855 26505385595e2c207af95d795e731312 630 ProSitePatterns PS00211 ABC transporters family signature. 524 538 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS02855 26505385595e2c207af95d795e731312 630 SUPERFAMILY SSF52540 380 623 5.96E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS12475 ed035d9707c0a44e9e8694dd4e641201 231 Gene3D G3DSA:3.40.50.1000 92 230 8.4E-25 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS12475 ed035d9707c0a44e9e8694dd4e641201 231 SUPERFAMILY SSF56784 19 229 1.38E-40 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS12475 ed035d9707c0a44e9e8694dd4e641201 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 23 202 1.8E-20 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS12475 ed035d9707c0a44e9e8694dd4e641201 231 Gene3D G3DSA:1.10.150.240 36 91 5.9E-16 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CFK41_RS04540 d47296ea669ee3ce69304e3fe0fbed94 715 Hamap MF_00054_B Elongation factor G [fusA]. 8 712 107.403 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CFK41_RS04540 d47296ea669ee3ce69304e3fe0fbed94 715 Gene3D G3DSA:3.30.230.10 510 634 4.8E-41 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CFK41_RS04540 d47296ea669ee3ce69304e3fe0fbed94 715 Pfam PF00679 Elongation factor G C-terminus 621 707 4.7E-31 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CFK41_RS04540 d47296ea669ee3ce69304e3fe0fbed94 715 Gene3D G3DSA:3.30.70.240 635 712 3.2E-31 T 28-03-2018 CFK41_RS04540 d47296ea669ee3ce69304e3fe0fbed94 715 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.1E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS04540 d47296ea669ee3ce69304e3fe0fbed94 715 PRINTS PR00315 GTP-binding elongation factor signature 80 90 2.1E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS04540 d47296ea669ee3ce69304e3fe0fbed94 715 PRINTS PR00315 GTP-binding elongation factor signature 132 141 2.1E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS04540 d47296ea669ee3ce69304e3fe0fbed94 715 PRINTS PR00315 GTP-binding elongation factor signature 96 107 2.1E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS04540 d47296ea669ee3ce69304e3fe0fbed94 715 PRINTS PR00315 GTP-binding elongation factor signature 60 68 2.1E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS04540 d47296ea669ee3ce69304e3fe0fbed94 715 Gene3D G3DSA:2.40.30.10 297 415 5.3E-30 T 28-03-2018 CFK41_RS04540 d47296ea669ee3ce69304e3fe0fbed94 715 SUPERFAMILY SSF50447 281 421 1.48E-34 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CFK41_RS04540 d47296ea669ee3ce69304e3fe0fbed94 715 Pfam PF00009 Elongation factor Tu GTP binding domain 11 298 1.0E-65 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS04540 d47296ea669ee3ce69304e3fe0fbed94 715 Pfam PF14492 Elongation Factor G, domain II 421 495 5.1E-34 T 28-03-2018 CFK41_RS04540 d47296ea669ee3ce69304e3fe0fbed94 715 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CFK41_RS04540 d47296ea669ee3ce69304e3fe0fbed94 715 SUPERFAMILY SSF54211 496 620 1.9E-38 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CFK41_RS04540 d47296ea669ee3ce69304e3fe0fbed94 715 TIGRFAM TIGR00484 EF-G: translation elongation factor G 8 712 0.0 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CFK41_RS04540 d47296ea669ee3ce69304e3fe0fbed94 715 Gene3D G3DSA:3.40.50.300 7 296 4.9E-59 T 28-03-2018 CFK41_RS04540 d47296ea669ee3ce69304e3fe0fbed94 715 SUPERFAMILY SSF54980 624 711 5.04E-31 T 28-03-2018 IPR035647 EF-G domain III/V-like CFK41_RS04540 d47296ea669ee3ce69304e3fe0fbed94 715 Pfam PF03144 Elongation factor Tu domain 2 341 408 2.0E-15 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CFK41_RS04540 d47296ea669ee3ce69304e3fe0fbed94 715 SUPERFAMILY SSF54980 421 498 7.55E-25 T 28-03-2018 IPR035647 EF-G domain III/V-like CFK41_RS04540 d47296ea669ee3ce69304e3fe0fbed94 715 SMART SM00838 621 708 8.0E-58 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CFK41_RS04540 d47296ea669ee3ce69304e3fe0fbed94 715 SMART SM00889 497 619 1.8E-67 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CFK41_RS04540 d47296ea669ee3ce69304e3fe0fbed94 715 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 182 1.0E-36 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CFK41_RS04540 d47296ea669ee3ce69304e3fe0fbed94 715 Pfam PF03764 Elongation factor G, domain IV 496 619 2.2E-44 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CFK41_RS04540 d47296ea669ee3ce69304e3fe0fbed94 715 SUPERFAMILY SSF52540 8 298 6.9E-106 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS04540 d47296ea669ee3ce69304e3fe0fbed94 715 Gene3D G3DSA:3.30.70.870 416 509 2.4E-37 T 28-03-2018 CFK41_RS11270 775fe8f5bdc63b63c69b845bce7e209a 453 Gene3D G3DSA:2.30.30.240 16 84 4.7E-10 T 28-03-2018 CFK41_RS11270 775fe8f5bdc63b63c69b845bce7e209a 453 Pfam PF00571 CBS domain 292 354 0.005 T 28-03-2018 IPR000644 CBS domain CFK41_RS11270 775fe8f5bdc63b63c69b845bce7e209a 453 Pfam PF00571 CBS domain 360 414 7.3E-9 T 28-03-2018 IPR000644 CBS domain CFK41_RS11270 775fe8f5bdc63b63c69b845bce7e209a 453 SUPERFAMILY SSF158791 172 288 1.96E-31 T 28-03-2018 CFK41_RS11270 775fe8f5bdc63b63c69b845bce7e209a 453 SMART SM00924 188 291 2.1E-36 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CFK41_RS11270 775fe8f5bdc63b63c69b845bce7e209a 453 SUPERFAMILY SSF54631 290 426 1.52E-26 T 28-03-2018 CFK41_RS11270 775fe8f5bdc63b63c69b845bce7e209a 453 SMART SM00116 367 415 3.7E-4 T 28-03-2018 IPR000644 CBS domain CFK41_RS11270 775fe8f5bdc63b63c69b845bce7e209a 453 SMART SM00116 298 356 90.0 T 28-03-2018 IPR000644 CBS domain CFK41_RS11270 775fe8f5bdc63b63c69b845bce7e209a 453 Gene3D G3DSA:3.10.580.10 286 452 2.7E-23 T 28-03-2018 CFK41_RS11270 775fe8f5bdc63b63c69b845bce7e209a 453 Pfam PF03448 MgtE intracellular N domain 188 288 8.6E-28 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CFK41_RS11270 775fe8f5bdc63b63c69b845bce7e209a 453 Gene3D G3DSA:1.25.60.10 169 285 2.8E-24 T 28-03-2018 CFK41_RS05910 c9daf9a59054c294d5c858510edc4807 59 Gene3D G3DSA:1.10.287.1060 3 59 4.5E-4 T 28-03-2018 CFK41_RS06950 e1f827084d49287dbe0aa100311baa3f 470 SUPERFAMILY SSF50621 305 468 2.07E-43 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CFK41_RS06950 e1f827084d49287dbe0aa100311baa3f 470 SUPERFAMILY SSF51419 60 331 4.51E-75 T 28-03-2018 IPR029066 PLP-binding barrel CFK41_RS06950 e1f827084d49287dbe0aa100311baa3f 470 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 337 426 2.0E-13 T 28-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CFK41_RS06950 e1f827084d49287dbe0aa100311baa3f 470 Gene3D G3DSA:2.40.37.10 317 469 2.2E-34 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CFK41_RS06950 e1f827084d49287dbe0aa100311baa3f 470 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 49 469 37.944 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CFK41_RS06950 e1f827084d49287dbe0aa100311baa3f 470 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 38 468 7.6E-134 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CFK41_RS06950 e1f827084d49287dbe0aa100311baa3f 470 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 96 114 - T 28-03-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site CFK41_RS06950 e1f827084d49287dbe0aa100311baa3f 470 Gene3D G3DSA:3.20.20.10 68 316 1.7E-65 T 28-03-2018 IPR029066 PLP-binding barrel CFK41_RS06950 e1f827084d49287dbe0aa100311baa3f 470 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 231 244 4.1E-14 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CFK41_RS06950 e1f827084d49287dbe0aa100311baa3f 470 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 116 128 4.1E-14 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CFK41_RS06950 e1f827084d49287dbe0aa100311baa3f 470 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 96 114 4.1E-14 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CFK41_RS06950 e1f827084d49287dbe0aa100311baa3f 470 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 320 339 4.1E-14 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CFK41_RS06950 e1f827084d49287dbe0aa100311baa3f 470 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 426 439 4.1E-14 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CFK41_RS06950 e1f827084d49287dbe0aa100311baa3f 470 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 71 329 3.2E-60 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CFK41_RS06950 e1f827084d49287dbe0aa100311baa3f 470 PRINTS PR01181 Diaminopimelate decarboxylase signature 114 131 8.2E-25 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CFK41_RS06950 e1f827084d49287dbe0aa100311baa3f 470 PRINTS PR01181 Diaminopimelate decarboxylase signature 203 212 8.2E-25 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CFK41_RS06950 e1f827084d49287dbe0aa100311baa3f 470 PRINTS PR01181 Diaminopimelate decarboxylase signature 436 458 8.2E-25 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CFK41_RS06950 e1f827084d49287dbe0aa100311baa3f 470 PRINTS PR01181 Diaminopimelate decarboxylase signature 353 371 8.2E-25 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CFK41_RS06950 e1f827084d49287dbe0aa100311baa3f 470 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 270 283 - T 28-03-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site CFK41_RS04445 1036cd70bdf225224998c753fb98e86c 96 Pfam PF11222 Protein of unknown function (DUF3017) 21 92 4.0E-9 T 28-03-2018 IPR021385 Protein of unknown function DUF3017 CFK41_RS11050 690a37c73f4bbdf7a430ecfb5015300d 193 PIRSF PIRSF037394 1 192 3.3E-56 T 28-03-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted CFK41_RS11050 690a37c73f4bbdf7a430ecfb5015300d 193 Pfam PF09819 ABC-type cobalt transport system, permease component 7 127 1.7E-36 T 28-03-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted CFK41_RS01440 f57cbdb06a182eb1e4c7ca7d447d0ec1 226 Pfam PF04854 Protein of unknown function, DUF624 20 86 7.6E-7 T 28-03-2018 IPR006938 Protein of unknown function DUF624 CFK41_RS14690 21228fbf8e81c13a15619045d47e4545 284 Gene3D G3DSA:1.10.3720.10 9 271 1.9E-44 T 28-03-2018 CFK41_RS14690 21228fbf8e81c13a15619045d47e4545 284 SUPERFAMILY SSF161098 16 284 3.55E-68 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS14690 21228fbf8e81c13a15619045d47e4545 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 276 3.5E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS10060 50761ce9d44b3a9e978e3d1f955c7335 152 SUPERFAMILY SSF51316 14 143 2.72E-50 T 28-03-2018 IPR011057 Mss4-like CFK41_RS10060 50761ce9d44b3a9e978e3d1f955c7335 152 Pfam PF01641 SelR domain 19 138 5.0E-49 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CFK41_RS10060 50761ce9d44b3a9e978e3d1f955c7335 152 Gene3D G3DSA:2.170.150.20 7 149 4.1E-53 T 28-03-2018 CFK41_RS10060 50761ce9d44b3a9e978e3d1f955c7335 152 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 16 138 5.2E-42 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CFK41_RS16240 9f764f1556959da0918bc0c1165a2c70 403 Gene3D G3DSA:3.30.420.40 233 378 3.4E-30 T 28-03-2018 CFK41_RS16240 9f764f1556959da0918bc0c1165a2c70 403 ProSitePatterns PS01125 ROK family signature. 226 253 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CFK41_RS16240 9f764f1556959da0918bc0c1165a2c70 403 Gene3D G3DSA:3.30.420.40 80 232 5.9E-30 T 28-03-2018 CFK41_RS16240 9f764f1556959da0918bc0c1165a2c70 403 Pfam PF00480 ROK family 147 395 4.6E-41 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CFK41_RS16240 9f764f1556959da0918bc0c1165a2c70 403 Pfam PF12802 MarR family 13 60 4.9E-7 T 28-03-2018 CFK41_RS16240 9f764f1556959da0918bc0c1165a2c70 403 Gene3D G3DSA:1.10.10.10 16 77 3.8E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS16240 9f764f1556959da0918bc0c1165a2c70 403 SUPERFAMILY SSF53067 85 396 7.21E-45 T 28-03-2018 CFK41_RS16240 9f764f1556959da0918bc0c1165a2c70 403 SUPERFAMILY SSF46785 13 75 1.17E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS10810 3c9c50aa89f6ba9d130749a0dc8d4c8d 299 Gene3D G3DSA:1.10.3720.10 13 286 2.2E-40 T 28-03-2018 CFK41_RS10810 3c9c50aa89f6ba9d130749a0dc8d4c8d 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 288 3.4E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS10810 3c9c50aa89f6ba9d130749a0dc8d4c8d 299 SUPERFAMILY SSF161098 25 299 2.88E-61 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS06415 2cbc21e9ddeb94f9fb01c5f9062caa4b 82 Pfam PF02467 Transcription factor WhiB 3 71 4.6E-25 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain CFK41_RS06415 2cbc21e9ddeb94f9fb01c5f9062caa4b 82 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 76 17.258 T 28-03-2018 IPR003482 Transcription factor WhiB CFK41_RS04680 6988cfffd92f6008b744f9de7d076d0b 155 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 13 152 2.3E-47 T 28-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04680 6988cfffd92f6008b744f9de7d076d0b 155 ProSitePatterns PS00475 Ribosomal protein L15 signature. 119 149 - T 28-03-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04680 6988cfffd92f6008b744f9de7d076d0b 155 Gene3D G3DSA:3.100.10.10 47 155 2.0E-31 T 28-03-2018 CFK41_RS04680 6988cfffd92f6008b744f9de7d076d0b 155 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 14 155 19.409 T 28-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 CFK41_RS04680 6988cfffd92f6008b744f9de7d076d0b 155 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 37 153 4.0E-34 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P CFK41_RS04680 6988cfffd92f6008b744f9de7d076d0b 155 SUPERFAMILY SSF52080 15 154 1.57E-42 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P CFK41_RS04205 10460a714e8540b2d1b8b8c221546b38 302 Gene3D G3DSA:1.10.3720.10 50 278 5.6E-28 T 28-03-2018 CFK41_RS04205 10460a714e8540b2d1b8b8c221546b38 302 SUPERFAMILY SSF161098 90 272 1.83E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS04205 10460a714e8540b2d1b8b8c221546b38 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 272 8.0E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS09585 4cbb309be5e0d5e88a71f7e8d61cda73 112 Gene3D G3DSA:2.102.10.10 4 112 5.9E-25 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CFK41_RS09585 4cbb309be5e0d5e88a71f7e8d61cda73 112 Pfam PF00355 Rieske [2Fe-2S] domain 6 92 1.8E-17 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CFK41_RS09585 4cbb309be5e0d5e88a71f7e8d61cda73 112 SUPERFAMILY SSF50022 3 106 3.54E-27 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CFK41_RS11125 1affc09cc32f08da877623b7660741f6 235 Pfam PF04167 Protein of unknown function (DUF402) 110 169 2.4E-15 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CFK41_RS11125 1affc09cc32f08da877623b7660741f6 235 Gene3D G3DSA:2.40.380.10 23 216 1.2E-55 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CFK41_RS11125 1affc09cc32f08da877623b7660741f6 235 SUPERFAMILY SSF159234 49 218 2.35E-35 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CFK41_RS07615 d14c92677f256dc4a906c813802f0138 257 Pfam PF13531 Bacterial extracellular solute-binding protein 37 254 1.6E-44 T 28-03-2018 CFK41_RS07615 d14c92677f256dc4a906c813802f0138 257 SUPERFAMILY SSF53850 36 254 1.0E-54 T 28-03-2018 CFK41_RS07615 d14c92677f256dc4a906c813802f0138 257 PIRSF PIRSF004846 5 257 1.8E-60 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 CFK41_RS07615 d14c92677f256dc4a906c813802f0138 257 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 42 253 6.2E-35 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 CFK41_RS07615 d14c92677f256dc4a906c813802f0138 257 Gene3D G3DSA:3.40.190.10 210 257 1.4E-4 T 28-03-2018 CFK41_RS07615 d14c92677f256dc4a906c813802f0138 257 Gene3D G3DSA:3.40.190.10 36 128 6.4E-26 T 28-03-2018 CFK41_RS07615 d14c92677f256dc4a906c813802f0138 257 Gene3D G3DSA:3.40.190.10 129 209 1.0E-20 T 28-03-2018 CFK41_RS01875 9a388f7b06bdcc23e23b9156d2343a6c 387 Gene3D G3DSA:3.20.20.30 1 348 2.4E-71 T 28-03-2018 CFK41_RS01875 9a388f7b06bdcc23e23b9156d2343a6c 387 SUPERFAMILY SSF51679 1 333 3.42E-71 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CFK41_RS01875 9a388f7b06bdcc23e23b9156d2343a6c 387 Pfam PF00296 Luciferase-like monooxygenase 1 295 1.6E-57 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CFK41_RS01875 9a388f7b06bdcc23e23b9156d2343a6c 387 TIGRFAM TIGR04036 LLM_CE1758_fam: putative luciferase-like monooxygenase, FMN-dependent, CE1758 family 1 355 1.7E-212 T 28-03-2018 IPR023934 Luciferase-like monooxygenase, FMN-dependent, putative CFK41_RS10665 90b30d4f736bdf5168ccaa9d4322fafa 392 Gene3D G3DSA:1.10.287.1060 315 378 0.22 T 28-03-2018 CFK41_RS10665 90b30d4f736bdf5168ccaa9d4322fafa 392 Gene3D G3DSA:1.10.287.850 1 84 1.2E-4 T 28-03-2018 CFK41_RS13715 61829495f1868289a1736501c9956e38 612 SMART SM00382 387 573 7.8E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS13715 61829495f1868289a1736501c9956e38 612 SUPERFAMILY SSF52540 360 597 5.21E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS13715 61829495f1868289a1736501c9956e38 612 ProSitePatterns PS00211 ABC transporters family signature. 499 513 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS13715 61829495f1868289a1736501c9956e38 612 Pfam PF00664 ABC transporter transmembrane region 20 296 2.1E-32 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS13715 61829495f1868289a1736501c9956e38 612 Gene3D G3DSA:1.20.1560.10 1 330 6.5E-47 T 28-03-2018 CFK41_RS13715 61829495f1868289a1736501c9956e38 612 Pfam PF00005 ABC transporter 378 527 7.0E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS13715 61829495f1868289a1736501c9956e38 612 Gene3D G3DSA:3.40.50.300 350 603 3.4E-73 T 28-03-2018 CFK41_RS13715 61829495f1868289a1736501c9956e38 612 SUPERFAMILY SSF90123 6 313 7.32E-51 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS08180 80c9a94115b331a7a274f03f9419cbb7 348 Pfam PF02562 PhoH-like protein 125 327 1.8E-93 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 CFK41_RS08180 80c9a94115b331a7a274f03f9419cbb7 348 SUPERFAMILY SSF52540 124 286 2.28E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS08180 80c9a94115b331a7a274f03f9419cbb7 348 Gene3D G3DSA:3.40.50.300 122 328 2.6E-29 T 28-03-2018 CFK41_RS07595 6d13119e354200b9ef2f477f4045d117 294 PRINTS PR00412 Epoxide hydrolase signature 66 81 5.6E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CFK41_RS07595 6d13119e354200b9ef2f477f4045d117 294 PRINTS PR00412 Epoxide hydrolase signature 121 134 5.6E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CFK41_RS07595 6d13119e354200b9ef2f477f4045d117 294 PRINTS PR00412 Epoxide hydrolase signature 268 290 5.6E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CFK41_RS07595 6d13119e354200b9ef2f477f4045d117 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 121 134 2.1E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CFK41_RS07595 6d13119e354200b9ef2f477f4045d117 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 66 81 2.1E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CFK41_RS07595 6d13119e354200b9ef2f477f4045d117 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 2.1E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CFK41_RS07595 6d13119e354200b9ef2f477f4045d117 294 SUPERFAMILY SSF53474 20 292 7.01E-53 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS07595 6d13119e354200b9ef2f477f4045d117 294 Pfam PF12697 Alpha/beta hydrolase family 44 285 5.2E-21 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CFK41_RS07595 6d13119e354200b9ef2f477f4045d117 294 Gene3D G3DSA:3.40.50.1820 8 294 7.7E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS09185 10ee357cf6deb5ca11806a5ed8beaee9 316 Pfam PF01040 UbiA prenyltransferase family 42 279 1.3E-61 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CFK41_RS09185 10ee357cf6deb5ca11806a5ed8beaee9 316 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 26 313 19.427 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CFK41_RS09185 10ee357cf6deb5ca11806a5ed8beaee9 316 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 81 103 - T 28-03-2018 IPR030470 UbiA prenyltransferase conserved site CFK41_RS09185 10ee357cf6deb5ca11806a5ed8beaee9 316 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 30 311 2.4E-91 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CFK41_RS15825 b926e2f136dbde12975718064c979610 366 Gene3D G3DSA:3.90.550.10 35 312 3.1E-40 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS15825 b926e2f136dbde12975718064c979610 366 SUPERFAMILY SSF53448 54 295 5.91E-41 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS15825 b926e2f136dbde12975718064c979610 366 Pfam PF00535 Glycosyl transferase family 2 69 195 1.7E-20 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CFK41_RS16755 0db45b0fec6dca5e02de9c3503ae8729 404 SUPERFAMILY SSF103473 3 398 5.36E-35 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS16755 0db45b0fec6dca5e02de9c3503ae8729 404 Gene3D G3DSA:1.20.1250.20 206 403 8.2E-18 T 28-03-2018 CFK41_RS16755 0db45b0fec6dca5e02de9c3503ae8729 404 Pfam PF07690 Major Facilitator Superfamily 254 394 7.0E-10 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS16755 0db45b0fec6dca5e02de9c3503ae8729 404 Pfam PF07690 Major Facilitator Superfamily 12 242 1.9E-14 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS16755 0db45b0fec6dca5e02de9c3503ae8729 404 Gene3D G3DSA:1.20.1250.20 2 197 3.7E-16 T 28-03-2018 CFK41_RS15915 d3dbcfb7e1381b56ab2c80af3dc099bf 396 Pfam PF01238 Phosphomannose isomerase type I 3 358 7.8E-62 T 28-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CFK41_RS15915 d3dbcfb7e1381b56ab2c80af3dc099bf 396 Gene3D G3DSA:2.60.120.10 301 396 3.6E-18 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CFK41_RS15915 d3dbcfb7e1381b56ab2c80af3dc099bf 396 SUPERFAMILY SSF51182 2 378 2.52E-84 T 28-03-2018 IPR011051 RmlC-like cupin domain CFK41_RS15915 d3dbcfb7e1381b56ab2c80af3dc099bf 396 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 9 387 3.5E-66 T 28-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CFK41_RS15915 d3dbcfb7e1381b56ab2c80af3dc099bf 396 ProSitePatterns PS00966 Phosphomannose isomerase type I signature 2. 260 285 - T 28-03-2018 IPR018050 Phosphomannose isomerase, type I, conserved site GO:0004476 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CFK41_RS15915 d3dbcfb7e1381b56ab2c80af3dc099bf 396 ProSitePatterns PS00965 Phosphomannose isomerase type I signature 1. 122 130 - T 28-03-2018 IPR018050 Phosphomannose isomerase, type I, conserved site GO:0004476 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CFK41_RS15915 d3dbcfb7e1381b56ab2c80af3dc099bf 396 PRINTS PR00714 Phosphomannose isomerase type I signature 77 98 5.2E-54 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CFK41_RS15915 d3dbcfb7e1381b56ab2c80af3dc099bf 396 PRINTS PR00714 Phosphomannose isomerase type I signature 241 260 5.2E-54 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CFK41_RS15915 d3dbcfb7e1381b56ab2c80af3dc099bf 396 PRINTS PR00714 Phosphomannose isomerase type I signature 279 298 5.2E-54 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CFK41_RS15915 d3dbcfb7e1381b56ab2c80af3dc099bf 396 PRINTS PR00714 Phosphomannose isomerase type I signature 225 240 5.2E-54 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CFK41_RS15915 d3dbcfb7e1381b56ab2c80af3dc099bf 396 PRINTS PR00714 Phosphomannose isomerase type I signature 31 46 5.2E-54 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CFK41_RS15915 d3dbcfb7e1381b56ab2c80af3dc099bf 396 PRINTS PR00714 Phosphomannose isomerase type I signature 260 279 5.2E-54 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CFK41_RS15915 d3dbcfb7e1381b56ab2c80af3dc099bf 396 PRINTS PR00714 Phosphomannose isomerase type I signature 4 22 5.2E-54 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CFK41_RS15915 d3dbcfb7e1381b56ab2c80af3dc099bf 396 PRINTS PR00714 Phosphomannose isomerase type I signature 122 145 5.2E-54 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CFK41_RS15915 d3dbcfb7e1381b56ab2c80af3dc099bf 396 PIRSF PIRSF001480 1 396 1.6E-92 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CFK41_RS15915 d3dbcfb7e1381b56ab2c80af3dc099bf 396 Gene3D G3DSA:2.60.120.10 1 300 3.4E-70 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CFK41_RS01560 9e7cee16b85df76839eb6b9e59798512 430 Gene3D G3DSA:3.30.43.10 6 71 1.3E-6 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CFK41_RS01560 9e7cee16b85df76839eb6b9e59798512 430 Gene3D G3DSA:3.30.465.10 72 191 3.5E-26 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CFK41_RS01560 9e7cee16b85df76839eb6b9e59798512 430 Gene3D G3DSA:3.40.462.10 302 396 0.002 T 28-03-2018 IPR016170 Vanillyl-alcohol oxidase/Cytokinin dehydrogenase C-terminal domain CFK41_RS01560 9e7cee16b85df76839eb6b9e59798512 430 Pfam PF04030 D-arabinono-1,4-lactone oxidase 300 426 1.4E-21 T 28-03-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 CFK41_RS01560 9e7cee16b85df76839eb6b9e59798512 430 PIRSF PIRSF000136 10 208 9.2E-35 T 28-03-2018 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 CFK41_RS01560 9e7cee16b85df76839eb6b9e59798512 430 PIRSF PIRSF000136 297 430 5.7E-10 T 28-03-2018 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 CFK41_RS01560 9e7cee16b85df76839eb6b9e59798512 430 Pfam PF01565 FAD binding domain 32 158 7.4E-19 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CFK41_RS01560 9e7cee16b85df76839eb6b9e59798512 430 SUPERFAMILY SSF56176 10 188 3.64E-32 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CFK41_RS02030 644903809b320f4b92d1a68e4d1ebeef 379 SUPERFAMILY SSF47090 147 194 4.47E-8 T 28-03-2018 IPR002477 Peptidoglycan binding-like CFK41_RS02030 644903809b320f4b92d1a68e4d1ebeef 379 Gene3D G3DSA:1.20.141.10 147 168 3.0E-5 T 28-03-2018 CFK41_RS02030 644903809b320f4b92d1a68e4d1ebeef 379 Gene3D G3DSA:1.20.141.10 169 204 1.6E-5 T 28-03-2018 CFK41_RS02030 644903809b320f4b92d1a68e4d1ebeef 379 SUPERFAMILY SSF47090 94 145 1.73E-11 T 28-03-2018 IPR002477 Peptidoglycan binding-like CFK41_RS02030 644903809b320f4b92d1a68e4d1ebeef 379 Pfam PF01471 Putative peptidoglycan binding domain 94 141 2.3E-9 T 28-03-2018 IPR002477 Peptidoglycan binding-like CFK41_RS02030 644903809b320f4b92d1a68e4d1ebeef 379 Pfam PF01471 Putative peptidoglycan binding domain 158 193 3.3E-6 T 28-03-2018 IPR002477 Peptidoglycan binding-like CFK41_RS02030 644903809b320f4b92d1a68e4d1ebeef 379 Gene3D G3DSA:1.10.101.10 87 146 2.2E-10 T 28-03-2018 IPR002477 Peptidoglycan binding-like CFK41_RS02030 644903809b320f4b92d1a68e4d1ebeef 379 Gene3D G3DSA:3.90.70.10 220 378 9.7E-8 T 28-03-2018 CFK41_RS04015 c69d894921e791f6e3b4f586f73555f8 1319 Gene3D G3DSA:3.30.300.30 423 540 5.9E-22 T 28-03-2018 CFK41_RS04015 c69d894921e791f6e3b4f586f73555f8 1319 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 793 821 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CFK41_RS04015 c69d894921e791f6e3b4f586f73555f8 1319 Pfam PF00501 AMP-binding enzyme 45 427 3.4E-69 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CFK41_RS04015 c69d894921e791f6e3b4f586f73555f8 1319 Gene3D G3DSA:1.10.1200.10 541 608 2.3E-16 T 28-03-2018 CFK41_RS04015 c69d894921e791f6e3b4f586f73555f8 1319 SMART SM00823 Phosphopantetheine attachment site 533 601 2.8E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CFK41_RS04015 c69d894921e791f6e3b4f586f73555f8 1319 TIGRFAM TIGR02353 NRPS_term_dom: non-ribosomal peptide synthetase terminal domain of unknown function 620 1310 1.2E-210 T 28-03-2018 IPR012728 Non-ribosomal peptide synthetase, C-terminal CFK41_RS04015 c69d894921e791f6e3b4f586f73555f8 1319 Gene3D G3DSA:2.160.10.10 732 840 9.7E-16 T 28-03-2018 CFK41_RS04015 c69d894921e791f6e3b4f586f73555f8 1319 Gene3D G3DSA:3.40.50.980 186 342 6.1E-34 T 28-03-2018 CFK41_RS04015 c69d894921e791f6e3b4f586f73555f8 1319 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 784 817 2.1E-5 T 28-03-2018 IPR001451 Hexapeptide repeat CFK41_RS04015 c69d894921e791f6e3b4f586f73555f8 1319 SUPERFAMILY SSF47336 529 598 2.73E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CFK41_RS04015 c69d894921e791f6e3b4f586f73555f8 1319 SUPERFAMILY SSF51161 1197 1313 8.18E-17 T 28-03-2018 IPR011004 Trimeric LpxA-like CFK41_RS04015 c69d894921e791f6e3b4f586f73555f8 1319 SUPERFAMILY SSF56801 38 545 2.88E-110 T 28-03-2018 CFK41_RS04015 c69d894921e791f6e3b4f586f73555f8 1319 SUPERFAMILY SSF51161 904 1078 6.1E-17 T 28-03-2018 IPR011004 Trimeric LpxA-like CFK41_RS04015 c69d894921e791f6e3b4f586f73555f8 1319 SUPERFAMILY SSF51161 734 836 2.22E-19 T 28-03-2018 IPR011004 Trimeric LpxA-like CFK41_RS04015 c69d894921e791f6e3b4f586f73555f8 1319 Gene3D G3DSA:3.40.50.980 36 185 7.6E-33 T 28-03-2018 CFK41_RS04015 c69d894921e791f6e3b4f586f73555f8 1319 ProSitePatterns PS00455 Putative AMP-binding domain signature. 180 191 - T 28-03-2018 IPR020845 AMP-binding, conserved site CFK41_RS04015 c69d894921e791f6e3b4f586f73555f8 1319 Pfam PF00550 Phosphopantetheine attachment site 535 597 6.6E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CFK41_RS04015 c69d894921e791f6e3b4f586f73555f8 1319 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 66 450 9.6E-102 T 28-03-2018 IPR010071 Amino acid adenylation domain CFK41_RS04015 c69d894921e791f6e3b4f586f73555f8 1319 Gene3D G3DSA:2.30.38.10 343 418 5.0E-14 T 28-03-2018 CFK41_RS04015 c69d894921e791f6e3b4f586f73555f8 1319 Gene3D G3DSA:2.160.10.10 1131 1312 1.9E-12 T 28-03-2018 CFK41_RS04015 c69d894921e791f6e3b4f586f73555f8 1319 Gene3D G3DSA:2.160.10.10 918 1074 4.4E-9 T 28-03-2018 CFK41_RS12370 327520254b72046b311c592fd41bb2be 296 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 240 253 - T 28-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site CFK41_RS12370 327520254b72046b311c592fd41bb2be 296 Pfam PF02629 CoA binding domain 6 104 1.7E-25 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CFK41_RS12370 327520254b72046b311c592fd41bb2be 296 SUPERFAMILY SSF51735 1 128 5.02E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS12370 327520254b72046b311c592fd41bb2be 296 Gene3D G3DSA:3.40.50.261 126 296 1.4E-47 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CFK41_RS12370 327520254b72046b311c592fd41bb2be 296 SMART SM00881 4 105 9.0E-30 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CFK41_RS12370 327520254b72046b311c592fd41bb2be 296 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 291 3.9E-125 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CFK41_RS12370 327520254b72046b311c592fd41bb2be 296 Pfam PF00549 CoA-ligase 158 275 8.8E-15 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CFK41_RS12370 327520254b72046b311c592fd41bb2be 296 Gene3D G3DSA:3.40.50.720 1 125 2.8E-39 T 28-03-2018 CFK41_RS12370 327520254b72046b311c592fd41bb2be 296 PIRSF PIRSF001553 1 295 1.3E-117 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CFK41_RS12370 327520254b72046b311c592fd41bb2be 296 SUPERFAMILY SSF52210 129 290 8.11E-45 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CFK41_RS12370 327520254b72046b311c592fd41bb2be 296 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 292 39.71 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CFK41_RS12370 327520254b72046b311c592fd41bb2be 296 PRINTS PR01798 Succinyl-CoA synthase signature 212 225 3.1E-34 T 28-03-2018 CFK41_RS12370 327520254b72046b311c592fd41bb2be 296 PRINTS PR01798 Succinyl-CoA synthase signature 244 261 3.1E-34 T 28-03-2018 CFK41_RS12370 327520254b72046b311c592fd41bb2be 296 PRINTS PR01798 Succinyl-CoA synthase signature 87 104 3.1E-34 T 28-03-2018 CFK41_RS12370 327520254b72046b311c592fd41bb2be 296 PRINTS PR01798 Succinyl-CoA synthase signature 181 199 3.1E-34 T 28-03-2018 CFK41_RS12370 327520254b72046b311c592fd41bb2be 296 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 158 185 - T 28-03-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site CFK41_RS06995 ade1c24dfd2be905e661c48c2dc4a10f 670 SUPERFAMILY SSF55347 134 305 6.05E-33 T 28-03-2018 CFK41_RS06995 ade1c24dfd2be905e661c48c2dc4a10f 670 Pfam PF00248 Aldo/keto reductase family 385 663 2.0E-44 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS06995 ade1c24dfd2be905e661c48c2dc4a10f 670 Gene3D G3DSA:3.20.20.100 372 667 4.7E-58 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS06995 ade1c24dfd2be905e661c48c2dc4a10f 670 Gene3D G3DSA:3.40.50.720 1 141 1.1E-37 T 28-03-2018 CFK41_RS06995 ade1c24dfd2be905e661c48c2dc4a10f 670 Gene3D G3DSA:3.30.360.10 142 341 1.3E-32 T 28-03-2018 CFK41_RS06995 ade1c24dfd2be905e661c48c2dc4a10f 670 SUPERFAMILY SSF51430 364 664 1.57E-62 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS06995 ade1c24dfd2be905e661c48c2dc4a10f 670 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 126 1.3E-20 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS06995 ade1c24dfd2be905e661c48c2dc4a10f 670 SUPERFAMILY SSF51735 5 160 7.62E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS14350 d5179468f271bc1e9c9f15350a9451af 363 Gene3D G3DSA:3.40.50.2300 87 196 7.0E-21 T 28-03-2018 CFK41_RS14350 d5179468f271bc1e9c9f15350a9451af 363 Pfam PF08220 DeoR-like helix-turn-helix domain 6 60 4.9E-16 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CFK41_RS14350 d5179468f271bc1e9c9f15350a9451af 363 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CFK41_RS14350 d5179468f271bc1e9c9f15350a9451af 363 Gene3D G3DSA:1.10.10.10 1 65 1.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS14350 d5179468f271bc1e9c9f15350a9451af 363 SUPERFAMILY SSF53822 97 362 1.76E-38 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS14350 d5179468f271bc1e9c9f15350a9451af 363 Pfam PF13377 Periplasmic binding protein-like domain 199 359 1.8E-23 T 28-03-2018 CFK41_RS14350 d5179468f271bc1e9c9f15350a9451af 363 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 3.8E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CFK41_RS14350 d5179468f271bc1e9c9f15350a9451af 363 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 3.8E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CFK41_RS14350 d5179468f271bc1e9c9f15350a9451af 363 SUPERFAMILY SSF46785 3 59 5.74E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS14350 d5179468f271bc1e9c9f15350a9451af 363 Gene3D G3DSA:3.40.50.2300 197 362 1.9E-27 T 28-03-2018 CFK41_RS14350 d5179468f271bc1e9c9f15350a9451af 363 SMART SM00420 6 58 3.5E-17 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CFK41_RS11460 e6823ae890d849ffa03d4016946b8ee0 96 Pfam PF02325 YGGT family 11 90 2.0E-11 T 28-03-2018 IPR003425 CCB3/YggT GO:0016020 CFK41_RS09950 7dfe384f07bfc4a50647a505f295a923 637 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 37 532 1.0E-101 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CFK41_RS09950 7dfe384f07bfc4a50647a505f295a923 637 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 284 522 1.2E-55 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CFK41_RS09950 7dfe384f07bfc4a50647a505f295a923 637 Gene3D G3DSA:1.20.1640.10 318 539 1.7E-23 T 28-03-2018 CFK41_RS09950 7dfe384f07bfc4a50647a505f295a923 637 SUPERFAMILY SSF82866 336 539 3.79E-24 T 28-03-2018 CFK41_RS09950 7dfe384f07bfc4a50647a505f295a923 637 Pfam PF02355 Protein export membrane protein 358 535 1.3E-7 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CFK41_RS09950 7dfe384f07bfc4a50647a505f295a923 637 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 1 546 35.977 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CFK41_RS17300 ca915a18f40449910d79e5a15e027e91 209 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 91 193 3.5E-34 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CFK41_RS17300 ca915a18f40449910d79e5a15e027e91 209 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 160 167 - T 28-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CFK41_RS17300 ca915a18f40449910d79e5a15e027e91 209 PIRSF PIRSF000349 1 202 6.2E-75 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CFK41_RS17300 ca915a18f40449910d79e5a15e027e91 209 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 1.3E-21 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CFK41_RS17300 ca915a18f40449910d79e5a15e027e91 209 PRINTS PR01703 Manganese superoxide dismutase signature 158 170 1.3E-21 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CFK41_RS17300 ca915a18f40449910d79e5a15e027e91 209 PRINTS PR01703 Manganese superoxide dismutase signature 120 128 1.3E-21 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CFK41_RS17300 ca915a18f40449910d79e5a15e027e91 209 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 1.3E-21 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CFK41_RS17300 ca915a18f40449910d79e5a15e027e91 209 PRINTS PR01703 Manganese superoxide dismutase signature 67 80 1.3E-21 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CFK41_RS17300 ca915a18f40449910d79e5a15e027e91 209 Gene3D G3DSA:1.10.287.990 21 84 7.7E-22 T 28-03-2018 CFK41_RS17300 ca915a18f40449910d79e5a15e027e91 209 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 84 1.9E-31 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CFK41_RS17300 ca915a18f40449910d79e5a15e027e91 209 SUPERFAMILY SSF54719 84 198 9.3E-43 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CFK41_RS17300 ca915a18f40449910d79e5a15e027e91 209 SUPERFAMILY SSF46609 3 88 4.06E-32 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CFK41_RS01310 ac381e94302364ff3b6dd7f5aab32b12 389 SUPERFAMILY SSF55347 134 288 7.85E-7 T 28-03-2018 CFK41_RS01310 ac381e94302364ff3b6dd7f5aab32b12 389 SUPERFAMILY SSF51735 3 155 2.05E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS01310 ac381e94302364ff3b6dd7f5aab32b12 389 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 124 1.9E-15 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS01310 ac381e94302364ff3b6dd7f5aab32b12 389 Gene3D G3DSA:3.40.50.720 1 145 9.3E-29 T 28-03-2018 CFK41_RS01310 ac381e94302364ff3b6dd7f5aab32b12 389 Gene3D G3DSA:3.30.360.10 146 334 1.0E-13 T 28-03-2018 CFK41_RS11690 283fc0953c66ca825dc747da9d5674d6 104 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 4 99 4.0E-11 T 28-03-2018 IPR008407 Branched-chain amino acid transport, AzlD CFK41_RS16330 bfe09819343d11de9e8d3e6046b720c1 214 SUPERFAMILY SSF48498 99 206 2.16E-12 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CFK41_RS16330 bfe09819343d11de9e8d3e6046b720c1 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 3.1E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS16330 bfe09819343d11de9e8d3e6046b720c1 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 3.1E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS16330 bfe09819343d11de9e8d3e6046b720c1 214 Gene3D G3DSA:1.10.10.60 1 70 2.6E-18 T 28-03-2018 CFK41_RS16330 bfe09819343d11de9e8d3e6046b720c1 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 73 1.2E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS16330 bfe09819343d11de9e8d3e6046b720c1 214 SUPERFAMILY SSF46689 15 77 1.1E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS16330 bfe09819343d11de9e8d3e6046b720c1 214 Gene3D G3DSA:1.10.357.10 71 210 7.9E-15 T 28-03-2018 CFK41_RS17055 994d131508589e25c34b5e4535830e0b 283 Gene3D G3DSA:3.90.850.10 22 283 2.8E-74 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CFK41_RS17055 994d131508589e25c34b5e4535830e0b 283 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 75 277 1.1E-63 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CFK41_RS17055 994d131508589e25c34b5e4535830e0b 283 SUPERFAMILY SSF56529 64 279 9.42E-69 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CFK41_RS04010 00dfb717845ac46b7a5c79aa183c1fbd 440 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 305 317 8.4E-17 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CFK41_RS04010 00dfb717845ac46b7a5c79aa183c1fbd 440 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 135 150 8.4E-17 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CFK41_RS04010 00dfb717845ac46b7a5c79aa183c1fbd 440 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 182 197 8.4E-17 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CFK41_RS04010 00dfb717845ac46b7a5c79aa183c1fbd 440 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 286 301 8.4E-17 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CFK41_RS04010 00dfb717845ac46b7a5c79aa183c1fbd 440 Gene3D G3DSA:2.60.40.1730 12 200 1.3E-40 T 28-03-2018 CFK41_RS04010 00dfb717845ac46b7a5c79aa183c1fbd 440 Gene3D G3DSA:1.10.390.10 278 429 1.1E-33 T 28-03-2018 CFK41_RS04010 00dfb717845ac46b7a5c79aa183c1fbd 440 Pfam PF01433 Peptidase family M1 domain 233 425 4.1E-26 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CFK41_RS04010 00dfb717845ac46b7a5c79aa183c1fbd 440 SUPERFAMILY SSF55486 209 435 2.49E-49 T 28-03-2018 CFK41_RS04010 00dfb717845ac46b7a5c79aa183c1fbd 440 SUPERFAMILY SSF63737 9 198 6.54E-37 T 28-03-2018 CFK41_RS01750 3870ffa557e2c15423e7bfb56d9a8550 315 SUPERFAMILY SSF161098 35 315 4.45E-57 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01750 3870ffa557e2c15423e7bfb56d9a8550 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 306 1.5E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01750 3870ffa557e2c15423e7bfb56d9a8550 315 Gene3D G3DSA:1.10.3720.10 91 309 1.2E-36 T 28-03-2018 CFK41_RS06365 8d1ee82fdb3505401151e940a855b93f 1006 Gene3D G3DSA:3.10.450.50 720 1001 1.6E-32 T 28-03-2018 CFK41_RS06365 8d1ee82fdb3505401151e940a855b93f 1006 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 29 815 0.0 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CFK41_RS06365 8d1ee82fdb3505401151e940a855b93f 1006 ProSitePatterns PS01312 SecA family signature. 482 497 - T 28-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 CFK41_RS06365 8d1ee82fdb3505401151e940a855b93f 1006 Gene3D G3DSA:3.40.50.300 399 617 3.0E-51 T 28-03-2018 CFK41_RS06365 8d1ee82fdb3505401151e940a855b93f 1006 Pfam PF01043 SecA preprotein cross-linking domain 233 340 7.2E-35 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CFK41_RS06365 8d1ee82fdb3505401151e940a855b93f 1006 SUPERFAMILY SSF81767 233 350 1.05E-41 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CFK41_RS06365 8d1ee82fdb3505401151e940a855b93f 1006 PRINTS PR00906 SecA protein signature 116 126 7.9E-66 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CFK41_RS06365 8d1ee82fdb3505401151e940a855b93f 1006 PRINTS PR00906 SecA protein signature 169 189 7.9E-66 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CFK41_RS06365 8d1ee82fdb3505401151e940a855b93f 1006 PRINTS PR00906 SecA protein signature 358 375 7.9E-66 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CFK41_RS06365 8d1ee82fdb3505401151e940a855b93f 1006 PRINTS PR00906 SecA protein signature 62 86 7.9E-66 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CFK41_RS06365 8d1ee82fdb3505401151e940a855b93f 1006 PRINTS PR00906 SecA protein signature 395 408 7.9E-66 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CFK41_RS06365 8d1ee82fdb3505401151e940a855b93f 1006 PRINTS PR00906 SecA protein signature 321 343 7.9E-66 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CFK41_RS06365 8d1ee82fdb3505401151e940a855b93f 1006 PRINTS PR00906 SecA protein signature 100 114 7.9E-66 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CFK41_RS06365 8d1ee82fdb3505401151e940a855b93f 1006 SUPERFAMILY SSF52540 350 397 6.39E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS06365 8d1ee82fdb3505401151e940a855b93f 1006 SUPERFAMILY SSF52540 4 227 6.39E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS06365 8d1ee82fdb3505401151e940a855b93f 1006 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 831 19.386 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CFK41_RS06365 8d1ee82fdb3505401151e940a855b93f 1006 Gene3D G3DSA:1.10.3060.10 618 719 1.0E-23 T 28-03-2018 CFK41_RS06365 8d1ee82fdb3505401151e940a855b93f 1006 SUPERFAMILY SSF52540 400 609 8.06E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS06365 8d1ee82fdb3505401151e940a855b93f 1006 Pfam PF07517 SecA DEAD-like domain 7 383 1.0E-124 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CFK41_RS06365 8d1ee82fdb3505401151e940a855b93f 1006 SMART SM00958 228 340 3.1E-57 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CFK41_RS06365 8d1ee82fdb3505401151e940a855b93f 1006 SUPERFAMILY SSF81886 618 839 3.4E-64 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CFK41_RS06365 8d1ee82fdb3505401151e940a855b93f 1006 Pfam PF07516 SecA Wing and Scaffold domain 614 827 1.2E-58 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CFK41_RS06365 8d1ee82fdb3505401151e940a855b93f 1006 Gene3D G3DSA:3.40.50.300 293 398 2.1E-8 T 28-03-2018 CFK41_RS06365 8d1ee82fdb3505401151e940a855b93f 1006 Gene3D G3DSA:3.40.50.300 8 270 1.6E-53 T 28-03-2018 CFK41_RS06365 8d1ee82fdb3505401151e940a855b93f 1006 SMART SM00957 5 384 1.3E-263 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CFK41_RS04310 d7c36649dca98b6cd5360fe431f8bde9 566 Pfam PF00350 Dynamin family 61 219 1.6E-9 T 28-03-2018 IPR022812 Dynamin superfamily CFK41_RS04310 d7c36649dca98b6cd5360fe431f8bde9 566 SMART SM00382 57 244 0.0015 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS04310 d7c36649dca98b6cd5360fe431f8bde9 566 Gene3D G3DSA:3.40.50.300 32 284 3.5E-27 T 28-03-2018 CFK41_RS04310 d7c36649dca98b6cd5360fe431f8bde9 566 SUPERFAMILY SSF52540 55 270 9.05E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS05565 2840f8e0da534d1a7be278cdf059a837 165 SUPERFAMILY SSF52833 1 161 2.44E-39 T 28-03-2018 IPR012336 Thioredoxin-like fold CFK41_RS05565 2840f8e0da534d1a7be278cdf059a837 165 Pfam PF08534 Redoxin 20 159 1.1E-24 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CFK41_RS05565 2840f8e0da534d1a7be278cdf059a837 165 Hamap MF_00269 Probable thiol peroxidase [tpx]. 3 165 36.163 T 28-03-2018 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 CFK41_RS05565 2840f8e0da534d1a7be278cdf059a837 165 Gene3D G3DSA:3.40.30.10 1 165 1.1E-21 T 28-03-2018 CFK41_RS05565 2840f8e0da534d1a7be278cdf059a837 165 ProSitePatterns PS01265 Tpx family signature. 83 94 - T 28-03-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 CFK41_RS05525 c24a2b5ed5a63f678ae569e4f81ac820 521 SUPERFAMILY SSF51445 82 339 1.79E-20 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS05525 c24a2b5ed5a63f678ae569e4f81ac820 521 Gene3D G3DSA:3.20.20.80 64 366 3.4E-43 T 28-03-2018 CFK41_RS05525 c24a2b5ed5a63f678ae569e4f81ac820 521 Pfam PF02638 Glycosyl hydrolase-like 10 52 358 7.0E-85 T 28-03-2018 IPR003790 Glycosyl hydrolase-like 10 CFK41_RS08640 9c86972b338f4c11bee9c83ecf61f627 359 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 32 82 3.8E-25 T 28-03-2018 CFK41_RS08640 9c86972b338f4c11bee9c83ecf61f627 359 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 102 267 3.3E-20 T 28-03-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 CFK41_RS08640 9c86972b338f4c11bee9c83ecf61f627 359 PIRSF PIRSF017269 29 304 4.4E-80 T 28-03-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 CFK41_RS08640 9c86972b338f4c11bee9c83ecf61f627 359 Gene3D G3DSA:3.10.330.20 29 95 2.2E-20 T 28-03-2018 CFK41_RS08640 9c86972b338f4c11bee9c83ecf61f627 359 SUPERFAMILY SSF53335 34 292 2.84E-69 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS08640 9c86972b338f4c11bee9c83ecf61f627 359 Gene3D G3DSA:3.40.50.150 97 300 5.1E-36 T 28-03-2018 CFK41_RS01735 f7fa6f06f36af8926b6b780219360bdd 500 SUPERFAMILY SSF53850 23 499 4.99E-79 T 28-03-2018 CFK41_RS01735 f7fa6f06f36af8926b6b780219360bdd 500 Pfam PF13416 Bacterial extracellular solute-binding protein 60 292 8.0E-17 T 28-03-2018 CFK41_RS01735 f7fa6f06f36af8926b6b780219360bdd 500 Gene3D G3DSA:3.40.190.10 328 436 0.0034 T 28-03-2018 CFK41_RS01735 f7fa6f06f36af8926b6b780219360bdd 500 Gene3D G3DSA:3.40.190.10 35 203 1.8E-28 T 28-03-2018 CFK41_RS17440 609fef9e67896b9b79bfb422685b21e4 166 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 18 150 9.9E-40 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CFK41_RS17440 609fef9e67896b9b79bfb422685b21e4 166 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 12 155 26.508 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CFK41_RS17440 609fef9e67896b9b79bfb422685b21e4 166 Gene3D G3DSA:3.40.50.960 2 157 5.3E-54 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CFK41_RS17440 609fef9e67896b9b79bfb422685b21e4 166 SUPERFAMILY SSF52121 11 155 1.83E-50 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CFK41_RS17440 609fef9e67896b9b79bfb422685b21e4 166 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 17 151 9.8E-48 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CFK41_RS04505 99e4904ebae419e0484d3cd7c03bb7f1 172 Pfam PF00466 Ribosomal protein L10 2 98 4.5E-23 T 28-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 CFK41_RS04505 99e4904ebae419e0484d3cd7c03bb7f1 172 ProSitePatterns PS01109 Ribosomal protein L10 signature. 6 40 - T 28-03-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS04505 99e4904ebae419e0484d3cd7c03bb7f1 172 SUPERFAMILY SSF160369 1 168 4.05E-47 T 28-03-2018 CFK41_RS04505 99e4904ebae419e0484d3cd7c03bb7f1 172 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 158 23.598 T 28-03-2018 IPR022973 Ribosomal protein L10 CFK41_RS03320 3e8ef83921e64cd9159ca22e2d2795cb 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.9E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03320 3e8ef83921e64cd9159ca22e2d2795cb 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.9E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03320 3e8ef83921e64cd9159ca22e2d2795cb 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.9E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03320 3e8ef83921e64cd9159ca22e2d2795cb 235 SUPERFAMILY SSF51735 2 226 4.93E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS03320 3e8ef83921e64cd9159ca22e2d2795cb 235 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CFK41_RS03320 3e8ef83921e64cd9159ca22e2d2795cb 235 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 186 0.0063 T 28-03-2018 CFK41_RS03320 3e8ef83921e64cd9159ca22e2d2795cb 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.7E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03320 3e8ef83921e64cd9159ca22e2d2795cb 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.7E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03320 3e8ef83921e64cd9159ca22e2d2795cb 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.7E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03320 3e8ef83921e64cd9159ca22e2d2795cb 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.7E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03320 3e8ef83921e64cd9159ca22e2d2795cb 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.7E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03320 3e8ef83921e64cd9159ca22e2d2795cb 235 Gene3D G3DSA:3.40.50.720 1 233 2.3E-52 T 28-03-2018 CFK41_RS03320 3e8ef83921e64cd9159ca22e2d2795cb 235 Pfam PF00106 short chain dehydrogenase 3 200 5.5E-49 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS07255 82ab522becb47befa0c31dd53109f54c 358 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 246 265 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CFK41_RS07255 82ab522becb47befa0c31dd53109f54c 358 Hamap MF_01035 3-isopropylmalate dehydrogenase [leuB]. 12 355 56.192 T 28-03-2018 IPR023698 3-isopropylmalate dehydrogenase GO:0003862|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CFK41_RS07255 82ab522becb47befa0c31dd53109f54c 358 Gene3D G3DSA:3.40.718.10 6 357 6.5E-107 T 28-03-2018 CFK41_RS07255 82ab522becb47befa0c31dd53109f54c 358 SUPERFAMILY SSF53659 11 354 2.3E-107 T 28-03-2018 CFK41_RS07255 82ab522becb47befa0c31dd53109f54c 358 SMART SM01329 13 351 3.0E-157 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CFK41_RS07255 82ab522becb47befa0c31dd53109f54c 358 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 14 344 7.8E-86 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CFK41_RS08045 3e4fa5323a2fd4967b601fa96d16ef10 899 Gene3D G3DSA:3.40.50.980 527 681 8.5E-21 T 28-03-2018 CFK41_RS08045 3e4fa5323a2fd4967b601fa96d16ef10 899 Gene3D G3DSA:2.30.38.10 682 775 3.7E-15 T 28-03-2018 CFK41_RS08045 3e4fa5323a2fd4967b601fa96d16ef10 899 Gene3D G3DSA:3.30.300.30 787 887 4.0E-6 T 28-03-2018 CFK41_RS08045 3e4fa5323a2fd4967b601fa96d16ef10 899 ProSitePatterns PS00455 Putative AMP-binding domain signature. 521 532 - T 28-03-2018 IPR020845 AMP-binding, conserved site CFK41_RS08045 3e4fa5323a2fd4967b601fa96d16ef10 899 SUPERFAMILY SSF56801 346 889 8.63E-69 T 28-03-2018 CFK41_RS08045 3e4fa5323a2fd4967b601fa96d16ef10 899 Pfam PF00561 alpha/beta hydrolase fold 65 301 1.8E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CFK41_RS08045 3e4fa5323a2fd4967b601fa96d16ef10 899 Gene3D G3DSA:3.40.50.1820 31 321 9.4E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS08045 3e4fa5323a2fd4967b601fa96d16ef10 899 SUPERFAMILY SSF53474 43 314 9.73E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS08045 3e4fa5323a2fd4967b601fa96d16ef10 899 Pfam PF00501 AMP-binding enzyme 357 780 9.1E-54 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CFK41_RS08045 3e4fa5323a2fd4967b601fa96d16ef10 899 Gene3D G3DSA:3.40.50.980 342 526 1.6E-28 T 28-03-2018 CFK41_RS04440 26cfe2277750f973fe9fc6f9b6e52d9b 502 Gene3D G3DSA:1.10.40.30 425 474 4.6E-18 T 28-03-2018 CFK41_RS04440 26cfe2277750f973fe9fc6f9b6e52d9b 502 Pfam PF00206 Lyase 20 351 2.1E-95 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CFK41_RS04440 26cfe2277750f973fe9fc6f9b6e52d9b 502 Gene3D G3DSA:1.10.275.10 10 147 1.4E-53 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CFK41_RS04440 26cfe2277750f973fe9fc6f9b6e52d9b 502 Pfam PF10415 Fumarase C C-terminus 417 469 1.0E-16 T 28-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CFK41_RS04440 26cfe2277750f973fe9fc6f9b6e52d9b 502 ProSitePatterns PS00163 Fumarate lyases signature. 326 335 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CFK41_RS04440 26cfe2277750f973fe9fc6f9b6e52d9b 502 SUPERFAMILY SSF48557 12 469 6.19E-145 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CFK41_RS04440 26cfe2277750f973fe9fc6f9b6e52d9b 502 Gene3D G3DSA:1.20.200.10 148 424 5.0E-79 T 28-03-2018 CFK41_RS04440 26cfe2277750f973fe9fc6f9b6e52d9b 502 PRINTS PR00149 Fumarate lyase superfamily signature 280 307 1.2E-28 T 28-03-2018 IPR000362 Fumarate lyase family CFK41_RS04440 26cfe2277750f973fe9fc6f9b6e52d9b 502 PRINTS PR00149 Fumarate lyase superfamily signature 326 342 1.2E-28 T 28-03-2018 IPR000362 Fumarate lyase family CFK41_RS04440 26cfe2277750f973fe9fc6f9b6e52d9b 502 PRINTS PR00149 Fumarate lyase superfamily signature 144 162 1.2E-28 T 28-03-2018 IPR000362 Fumarate lyase family CFK41_RS04440 26cfe2277750f973fe9fc6f9b6e52d9b 502 PRINTS PR00149 Fumarate lyase superfamily signature 189 207 1.2E-28 T 28-03-2018 IPR000362 Fumarate lyase family CFK41_RS05975 8f172320b41d0f25e3dc9a0e32dc1a53 299 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 121 4.6E-34 T 28-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CFK41_RS05975 8f172320b41d0f25e3dc9a0e32dc1a53 299 Gene3D G3DSA:3.40.50.10860 11 138 7.8E-42 T 28-03-2018 CFK41_RS05975 8f172320b41d0f25e3dc9a0e32dc1a53 299 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 124 292 4.3E-57 T 28-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CFK41_RS05975 8f172320b41d0f25e3dc9a0e32dc1a53 299 SUPERFAMILY SSF53223 1 122 9.5E-36 T 28-03-2018 CFK41_RS05975 8f172320b41d0f25e3dc9a0e32dc1a53 299 SUPERFAMILY SSF51735 123 291 1.31E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS05975 8f172320b41d0f25e3dc9a0e32dc1a53 299 Gene3D G3DSA:3.40.50.720 139 274 9.7E-33 T 28-03-2018 CFK41_RS05975 8f172320b41d0f25e3dc9a0e32dc1a53 299 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 75 102 6.6E-62 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CFK41_RS05975 8f172320b41d0f25e3dc9a0e32dc1a53 299 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 266 284 6.6E-62 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CFK41_RS05975 8f172320b41d0f25e3dc9a0e32dc1a53 299 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 110 131 6.6E-62 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CFK41_RS05975 8f172320b41d0f25e3dc9a0e32dc1a53 299 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 159 179 6.6E-62 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CFK41_RS05975 8f172320b41d0f25e3dc9a0e32dc1a53 299 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 34 56 6.6E-62 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CFK41_RS05975 8f172320b41d0f25e3dc9a0e32dc1a53 299 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 210 239 6.6E-62 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CFK41_RS05975 8f172320b41d0f25e3dc9a0e32dc1a53 299 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 293 35.795 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CFK41_RS16695 094bff7178117b8bc717e0b8b9d40c68 168 SUPERFAMILY SSF53927 8 150 5.52E-36 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CFK41_RS16695 094bff7178117b8bc717e0b8b9d40c68 168 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 8 106 1.3E-20 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CFK41_RS16695 094bff7178117b8bc717e0b8b9d40c68 168 Gene3D G3DSA:3.40.140.10 2 154 1.0E-35 T 28-03-2018 CFK41_RS08400 e8a8c2ec4adfe1298183666af1f56c22 139 Pfam PF11253 Protein of unknown function (DUF3052) 16 137 1.8E-50 T 28-03-2018 IPR021412 Protein of unknown function DUF3052 CFK41_RS11725 4947002301e5c5111562ed0e4c4120a8 520 Pfam PF03734 L,D-transpeptidase catalytic domain 396 518 5.3E-22 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CFK41_RS11725 4947002301e5c5111562ed0e4c4120a8 520 SUPERFAMILY SSF141523 394 518 1.57E-28 T 28-03-2018 CFK41_RS11725 4947002301e5c5111562ed0e4c4120a8 520 Gene3D G3DSA:2.40.440.10 388 520 1.0E-31 T 28-03-2018 CFK41_RS11725 4947002301e5c5111562ed0e4c4120a8 520 Pfam PF12229 Putative peptidoglycan binding domain 94 196 1.3E-5 T 28-03-2018 IPR022029 Putative peptidoglycan binding domain CFK41_RS07835 4faaaf73bbb540e77c4b03e7b34962dc 545 Gene3D G3DSA:3.40.190.10 185 542 9.8E-39 T 28-03-2018 CFK41_RS07835 4faaaf73bbb540e77c4b03e7b34962dc 545 Pfam PF13416 Bacterial extracellular solute-binding protein 69 386 9.0E-11 T 28-03-2018 CFK41_RS07835 4faaaf73bbb540e77c4b03e7b34962dc 545 Gene3D G3DSA:3.40.190.10 48 184 3.3E-7 T 28-03-2018 CFK41_RS07835 4faaaf73bbb540e77c4b03e7b34962dc 545 SUPERFAMILY SSF53850 37 540 7.44E-62 T 28-03-2018 CFK41_RS00910 ab21adb8b98169516e10c26528ee7d0a 227 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 9 227 2.1E-69 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CFK41_RS00910 ab21adb8b98169516e10c26528ee7d0a 227 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 196 209 - T 28-03-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CFK41_RS00910 ab21adb8b98169516e10c26528ee7d0a 227 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 51 132 2.1E-17 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CFK41_RS00910 ab21adb8b98169516e10c26528ee7d0a 227 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 16 227 36.632 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CFK41_RS00910 ab21adb8b98169516e10c26528ee7d0a 227 Gene3D G3DSA:2.30.110.10 19 227 4.3E-65 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CFK41_RS00910 ab21adb8b98169516e10c26528ee7d0a 227 PIRSF PIRSF000190 2 227 1.3E-67 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CFK41_RS00910 ab21adb8b98169516e10c26528ee7d0a 227 SUPERFAMILY SSF50475 24 227 8.84E-60 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CFK41_RS00910 ab21adb8b98169516e10c26528ee7d0a 227 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 186 227 1.3E-16 T 28-03-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CFK41_RS03890 ec9e8f4be5abe40ca9368ac0af4f1297 331 Pfam PF00005 ABC transporter 30 168 1.8E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS03890 ec9e8f4be5abe40ca9368ac0af4f1297 331 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS03890 ec9e8f4be5abe40ca9368ac0af4f1297 331 SUPERFAMILY SSF52540 10 233 3.95E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS03890 ec9e8f4be5abe40ca9368ac0af4f1297 331 Gene3D G3DSA:3.40.50.300 13 278 2.9E-58 T 28-03-2018 CFK41_RS03890 ec9e8f4be5abe40ca9368ac0af4f1297 331 SMART SM00382 38 216 2.6E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS03995 0f116dbf1bdd5e08db10c9e71622f206 466 Pfam PF00083 Sugar (and other) transporter 16 230 1.4E-25 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CFK41_RS03995 0f116dbf1bdd5e08db10c9e71622f206 466 SUPERFAMILY SSF103473 11 432 8.11E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS03995 0f116dbf1bdd5e08db10c9e71622f206 466 Pfam PF07690 Major Facilitator Superfamily 254 432 1.9E-8 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS03995 0f116dbf1bdd5e08db10c9e71622f206 466 Gene3D G3DSA:1.20.1250.20 222 448 5.8E-23 T 28-03-2018 CFK41_RS03995 0f116dbf1bdd5e08db10c9e71622f206 466 Gene3D G3DSA:1.20.1250.20 6 221 1.8E-23 T 28-03-2018 CFK41_RS03995 0f116dbf1bdd5e08db10c9e71622f206 466 ProSitePatterns PS00217 Sugar transport proteins signature 2. 124 149 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CFK41_RS16750 a7187fb86ed9b5f9121498a08d66b0d4 225 SMART SM00422 1 70 7.1E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS16750 a7187fb86ed9b5f9121498a08d66b0d4 225 Gene3D G3DSA:1.10.1660.10 56 139 8.9E-4 T 28-03-2018 CFK41_RS16750 a7187fb86ed9b5f9121498a08d66b0d4 225 Gene3D G3DSA:1.10.1660.10 1 55 4.4E-19 T 28-03-2018 CFK41_RS16750 a7187fb86ed9b5f9121498a08d66b0d4 225 SUPERFAMILY SSF46955 1 103 3.63E-22 T 28-03-2018 IPR009061 Putative DNA-binding domain CFK41_RS16750 a7187fb86ed9b5f9121498a08d66b0d4 225 Pfam PF00376 MerR family regulatory protein 2 39 1.2E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS11770 f7129e45e664d08c65b5a6b531c29318 594 Gene3D G3DSA:3.90.960.10 255 399 3.7E-27 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CFK41_RS11770 f7129e45e664d08c65b5a6b531c29318 594 Gene3D G3DSA:3.30.930.10 400 481 1.6E-7 T 28-03-2018 CFK41_RS11770 f7129e45e664d08c65b5a6b531c29318 594 Gene3D G3DSA:3.30.930.10 25 254 5.6E-53 T 28-03-2018 CFK41_RS11770 f7129e45e664d08c65b5a6b531c29318 594 Pfam PF03129 Anticodon binding domain 499 589 6.5E-17 T 28-03-2018 IPR004154 Anticodon-binding CFK41_RS11770 f7129e45e664d08c65b5a6b531c29318 594 Pfam PF04073 Aminoacyl-tRNA editing domain 263 398 7.2E-16 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CFK41_RS11770 f7129e45e664d08c65b5a6b531c29318 594 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 480 6.5E-40 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS11770 f7129e45e664d08c65b5a6b531c29318 594 SUPERFAMILY SSF55826 287 403 1.28E-7 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CFK41_RS11770 f7129e45e664d08c65b5a6b531c29318 594 SUPERFAMILY SSF52954 486 590 2.29E-26 T 28-03-2018 IPR004154 Anticodon-binding CFK41_RS11770 f7129e45e664d08c65b5a6b531c29318 594 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 3 587 2.4E-160 T 28-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CFK41_RS11770 f7129e45e664d08c65b5a6b531c29318 594 SUPERFAMILY SSF55681 430 501 1.81E-86 T 28-03-2018 CFK41_RS11770 f7129e45e664d08c65b5a6b531c29318 594 SUPERFAMILY SSF55681 11 237 1.81E-86 T 28-03-2018 CFK41_RS11770 f7129e45e664d08c65b5a6b531c29318 594 Gene3D G3DSA:3.40.50.800 482 593 1.4E-27 T 28-03-2018 IPR004154 Anticodon-binding CFK41_RS11770 f7129e45e664d08c65b5a6b531c29318 594 PRINTS PR01046 Prolyl-tRNA synthetase signature 105 116 6.8E-15 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CFK41_RS11770 f7129e45e664d08c65b5a6b531c29318 594 PRINTS PR01046 Prolyl-tRNA synthetase signature 135 143 6.8E-15 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CFK41_RS11770 f7129e45e664d08c65b5a6b531c29318 594 PRINTS PR01046 Prolyl-tRNA synthetase signature 145 156 6.8E-15 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CFK41_RS11770 f7129e45e664d08c65b5a6b531c29318 594 PRINTS PR01046 Prolyl-tRNA synthetase signature 69 87 6.8E-15 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CFK41_RS11770 f7129e45e664d08c65b5a6b531c29318 594 Hamap MF_01569 Proline--tRNA ligase [proS]. 2 592 35.609 T 28-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CFK41_RS01610 6320e67382af67755a2be64449e89be8 303 Gene3D G3DSA:1.10.3720.10 24 290 3.9E-40 T 28-03-2018 CFK41_RS01610 6320e67382af67755a2be64449e89be8 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 293 2.5E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01610 6320e67382af67755a2be64449e89be8 303 SUPERFAMILY SSF161098 32 303 2.75E-66 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS00460 2f1aa396eaa5781dae9dfbb51dc769ed 496 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 302 454 2.4E-21 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CFK41_RS00460 2f1aa396eaa5781dae9dfbb51dc769ed 496 SUPERFAMILY SSF53067 262 493 6.26E-32 T 28-03-2018 CFK41_RS00460 2f1aa396eaa5781dae9dfbb51dc769ed 496 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 15 260 4.0E-35 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CFK41_RS00460 2f1aa396eaa5781dae9dfbb51dc769ed 496 Gene3D G3DSA:3.30.420.40 258 496 1.4E-37 T 28-03-2018 CFK41_RS00460 2f1aa396eaa5781dae9dfbb51dc769ed 496 Gene3D G3DSA:3.30.420.40 10 257 1.3E-53 T 28-03-2018 CFK41_RS00460 2f1aa396eaa5781dae9dfbb51dc769ed 496 SUPERFAMILY SSF53067 15 263 2.74E-46 T 28-03-2018 CFK41_RS00460 2f1aa396eaa5781dae9dfbb51dc769ed 496 PIRSF PIRSF000538 13 496 8.5E-76 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CFK41_RS10335 a0eb581356ab83a30ed616a566fb1585 220 Pfam PF02525 Flavodoxin-like fold 3 163 5.7E-15 T 28-03-2018 IPR003680 Flavodoxin-like fold CFK41_RS10335 a0eb581356ab83a30ed616a566fb1585 220 SUPERFAMILY SSF52218 4 203 5.94E-24 T 28-03-2018 IPR029039 Flavoprotein-like domain CFK41_RS10335 a0eb581356ab83a30ed616a566fb1585 220 Gene3D G3DSA:3.40.50.360 1 217 5.9E-23 T 28-03-2018 IPR029039 Flavoprotein-like domain CFK41_RS11350 fa3cdcf76f237b4e958fa989a54d96bf 109 SUPERFAMILY SSF54862 3 92 2.2E-21 T 28-03-2018 CFK41_RS11350 fa3cdcf76f237b4e958fa989a54d96bf 109 Gene3D G3DSA:3.30.70.20 27 49 4.2E-11 T 28-03-2018 CFK41_RS11350 fa3cdcf76f237b4e958fa989a54d96bf 109 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CFK41_RS11350 fa3cdcf76f237b4e958fa989a54d96bf 109 Gene3D G3DSA:3.30.70.20 50 95 2.0E-6 T 28-03-2018 CFK41_RS11350 fa3cdcf76f237b4e958fa989a54d96bf 109 PRINTS PR00354 7Fe ferredoxin signature 19 29 1.7E-16 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CFK41_RS11350 fa3cdcf76f237b4e958fa989a54d96bf 109 PRINTS PR00354 7Fe ferredoxin signature 9 19 1.7E-16 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CFK41_RS11350 fa3cdcf76f237b4e958fa989a54d96bf 109 PRINTS PR00354 7Fe ferredoxin signature 35 52 1.7E-16 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CFK41_RS11350 fa3cdcf76f237b4e958fa989a54d96bf 109 Gene3D G3DSA:3.30.70.20 2 26 0.23 T 28-03-2018 CFK41_RS11350 fa3cdcf76f237b4e958fa989a54d96bf 109 Pfam PF00037 4Fe-4S binding domain 34 56 3.3E-8 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CFK41_RS16265 5840d5f40d1baac010acfab15b087918 305 Gene3D G3DSA:3.30.470.20 99 294 1.1E-9 T 28-03-2018 CFK41_RS16265 5840d5f40d1baac010acfab15b087918 305 Gene3D G3DSA:3.40.50.20 2 98 9.6E-4 T 28-03-2018 CFK41_RS16265 5840d5f40d1baac010acfab15b087918 305 SUPERFAMILY SSF56059 95 277 3.05E-13 T 28-03-2018 CFK41_RS16490 fcd98b0431a49512c059048707ab27a4 523 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 355 507 3.5E-31 T 28-03-2018 IPR006512 YidE/YbjL duplication CFK41_RS16490 fcd98b0431a49512c059048707ab27a4 523 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 20 154 3.1E-21 T 28-03-2018 IPR006512 YidE/YbjL duplication CFK41_RS16490 fcd98b0431a49512c059048707ab27a4 523 Pfam PF02080 TrkA-C domain 270 336 8.4E-13 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CFK41_RS16490 fcd98b0431a49512c059048707ab27a4 523 Gene3D G3DSA:3.30.70.1450 258 342 8.9E-12 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CFK41_RS16490 fcd98b0431a49512c059048707ab27a4 523 Gene3D G3DSA:3.30.70.1450 178 257 9.0E-6 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CFK41_RS16490 fcd98b0431a49512c059048707ab27a4 523 SUPERFAMILY SSF116726 267 337 7.98E-11 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CFK41_RS16490 fcd98b0431a49512c059048707ab27a4 523 Pfam PF06826 Predicted Permease Membrane Region 13 165 3.0E-25 T 28-03-2018 IPR006512 YidE/YbjL duplication CFK41_RS16490 fcd98b0431a49512c059048707ab27a4 523 Pfam PF06826 Predicted Permease Membrane Region 351 520 1.7E-28 T 28-03-2018 IPR006512 YidE/YbjL duplication CFK41_RS02330 6c04f46dca387cb012051f864d681741 476 Gene3D G3DSA:3.60.15.10 10 266 1.8E-34 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS02330 6c04f46dca387cb012051f864d681741 476 SMART SM00450 370 465 9.3E-11 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS02330 6c04f46dca387cb012051f864d681741 476 SMART SM00450 269 369 1.5 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS02330 6c04f46dca387cb012051f864d681741 476 SUPERFAMILY SSF52821 365 462 4.98E-21 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS02330 6c04f46dca387cb012051f864d681741 476 SUPERFAMILY SSF56281 12 259 3.36E-46 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS02330 6c04f46dca387cb012051f864d681741 476 Gene3D G3DSA:3.40.250.10 267 361 2.3E-9 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS02330 6c04f46dca387cb012051f864d681741 476 Gene3D G3DSA:3.40.250.10 362 475 2.4E-18 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS02330 6c04f46dca387cb012051f864d681741 476 SUPERFAMILY SSF52821 235 352 1.96E-13 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS02330 6c04f46dca387cb012051f864d681741 476 Pfam PF00581 Rhodanese-like domain 378 460 3.4E-9 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS02330 6c04f46dca387cb012051f864d681741 476 Pfam PF00753 Metallo-beta-lactamase superfamily 11 192 7.5E-10 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS02330 6c04f46dca387cb012051f864d681741 476 SMART SM00849 12 192 9.4E-22 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS13175 d94fb68c24f85718471ab1647886c4f4 140 Gene3D G3DSA:3.30.300.20 45 140 6.6E-29 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CFK41_RS13175 d94fb68c24f85718471ab1647886c4f4 140 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 4 137 4.4E-52 T 28-03-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 CFK41_RS13175 d94fb68c24f85718471ab1647886c4f4 140 Pfam PF02566 OsmC-like protein 39 135 5.1E-19 T 28-03-2018 IPR003718 OsmC/Ohr family CFK41_RS13175 d94fb68c24f85718471ab1647886c4f4 140 SUPERFAMILY SSF82784 1 137 4.19E-41 T 28-03-2018 IPR003718 OsmC/Ohr family CFK41_RS13175 d94fb68c24f85718471ab1647886c4f4 140 Gene3D G3DSA:2.20.25.10 1 44 7.6E-16 T 28-03-2018 CFK41_RS09655 48dd44a2d5a973daa3c359748455b435 381 Gene3D G3DSA:1.10.10.10 291 380 2.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS09655 48dd44a2d5a973daa3c359748455b435 381 SUPERFAMILY SSF46785 324 376 6.43E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS09655 48dd44a2d5a973daa3c359748455b435 381 Pfam PF01022 Bacterial regulatory protein, arsR family 325 354 1.2E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS09655 48dd44a2d5a973daa3c359748455b435 381 SMART SM00418 317 377 0.0011 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS16690 ec3d1663c965938d5626e6df7b5322d7 312 Pfam PF01226 Formate/nitrite transporter 9 258 1.7E-64 T 28-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 CFK41_RS16690 ec3d1663c965938d5626e6df7b5322d7 312 Gene3D G3DSA:1.20.1080.10 4 269 1.8E-68 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CFK41_RS07395 13a88921a002e9329442839945551971 342 SUPERFAMILY SSF56042 159 328 4.53E-21 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CFK41_RS07395 13a88921a002e9329442839945551971 342 SUPERFAMILY SSF55326 18 153 2.22E-30 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CFK41_RS07395 13a88921a002e9329442839945551971 342 Gene3D G3DSA:3.30.1330.10 11 157 2.3E-28 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CFK41_RS07395 13a88921a002e9329442839945551971 342 Gene3D G3DSA:3.90.650.10 161 341 9.8E-29 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CFK41_RS07395 13a88921a002e9329442839945551971 342 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 19 305 3.7E-63 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CFK41_RS07395 13a88921a002e9329442839945551971 342 Pfam PF00586 AIR synthase related protein, N-terminal domain 42 152 6.9E-19 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CFK41_RS07395 13a88921a002e9329442839945551971 342 PIRSF PIRSF005303 14 341 3.2E-67 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CFK41_RS06930 191b94f2694c4e284080b091cc9c4bd5 269 Gene3D G3DSA:2.70.70.10 74 269 7.8E-41 T 28-03-2018 CFK41_RS06930 191b94f2694c4e284080b091cc9c4bd5 269 Pfam PF01551 Peptidase family M23 169 264 3.3E-27 T 28-03-2018 IPR016047 Peptidase M23 CFK41_RS06930 191b94f2694c4e284080b091cc9c4bd5 269 SUPERFAMILY SSF51261 130 268 2.46E-47 T 28-03-2018 IPR011055 Duplicated hybrid motif CFK41_RS14075 dddb82cf29634223c6ede6569c8126f2 155 Gene3D G3DSA:3.40.50.300 1 155 8.8E-21 T 28-03-2018 CFK41_RS14075 dddb82cf29634223c6ede6569c8126f2 155 SUPERFAMILY SSF52540 4 153 4.0E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS14075 dddb82cf29634223c6ede6569c8126f2 155 Pfam PF13671 AAA domain 4 142 1.1E-20 T 28-03-2018 CFK41_RS14930 c21c99ac590fe8c36d923c275135cc73 102 TIGRFAM TIGR03462 CarR_dom_SF: lycopene cyclase domain 1 94 2.0E-13 T 28-03-2018 IPR017825 Lycopene cyclase domain GO:0016872 KEGG: 00906+2.5.1.32+5.5.1.19|MetaCyc: PWY-5943|MetaCyc: PWY-5947|MetaCyc: PWY-7591 CFK41_RS04800 5258baad16eb1d6b411289a3af572436 324 Gene3D G3DSA:3.90.245.10 1 319 1.3E-88 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CFK41_RS04800 5258baad16eb1d6b411289a3af572436 324 SUPERFAMILY SSF53590 3 314 1.57E-81 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CFK41_RS04800 5258baad16eb1d6b411289a3af572436 324 ProSitePatterns PS01247 Inosine-uridine preferring nucleoside hydrolase family signature. 8 18 - T 28-03-2018 IPR015910 Inosine/uridine-preferring nucleoside hydrolase, conserved site GO:0016799 CFK41_RS04800 5258baad16eb1d6b411289a3af572436 324 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 4 307 6.0E-71 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CFK41_RS10265 334723391287bec2db1ae2c43a1fe804 355 Gene3D G3DSA:3.20.20.140 74 354 2.1E-69 T 28-03-2018 CFK41_RS10265 334723391287bec2db1ae2c43a1fe804 355 Pfam PF01026 TatD related DNase 77 347 3.0E-56 T 28-03-2018 IPR001130 TatD family GO:0016788 CFK41_RS10265 334723391287bec2db1ae2c43a1fe804 355 SUPERFAMILY SSF51556 75 348 2.27E-64 T 28-03-2018 IPR032466 Metal-dependent hydrolase CFK41_RS14295 1f23881c78e8f34220731848c59c39f8 490 Gene3D G3DSA:3.40.190.10 101 225 2.4E-21 T 28-03-2018 CFK41_RS14295 1f23881c78e8f34220731848c59c39f8 490 SUPERFAMILY SSF53850 97 484 6.73E-50 T 28-03-2018 CFK41_RS14295 1f23881c78e8f34220731848c59c39f8 490 Pfam PF01547 Bacterial extracellular solute-binding protein 112 398 1.0E-29 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CFK41_RS14295 1f23881c78e8f34220731848c59c39f8 490 Gene3D G3DSA:3.40.190.10 226 428 9.3E-26 T 28-03-2018 CFK41_RS14655 143ee149c2069fbec4fe71bcf7b8c552 542 SMART SM00813 300 534 2.0E-5 T 28-03-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 CFK41_RS14655 143ee149c2069fbec4fe71bcf7b8c552 542 Gene3D G3DSA:2.60.40.1180 399 542 3.1E-16 T 28-03-2018 CFK41_RS14655 143ee149c2069fbec4fe71bcf7b8c552 542 SUPERFAMILY SSF51445 17 404 4.73E-59 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS14655 143ee149c2069fbec4fe71bcf7b8c552 542 Gene3D G3DSA:3.20.20.80 18 398 3.2E-73 T 28-03-2018 CFK41_RS14655 143ee149c2069fbec4fe71bcf7b8c552 542 SUPERFAMILY SSF51011 388 540 8.27E-10 T 28-03-2018 CFK41_RS04120 d2746d1d3add347fe3eb8d1a95b3fad9 427 SUPERFAMILY SSF103473 6 411 6.54E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS04120 d2746d1d3add347fe3eb8d1a95b3fad9 427 Pfam PF07690 Major Facilitator Superfamily 26 263 3.4E-14 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS04120 d2746d1d3add347fe3eb8d1a95b3fad9 427 Gene3D G3DSA:1.20.1250.20 223 411 7.4E-23 T 28-03-2018 CFK41_RS04120 d2746d1d3add347fe3eb8d1a95b3fad9 427 Gene3D G3DSA:1.20.1250.20 2 208 2.8E-18 T 28-03-2018 CFK41_RS09765 2a179a9bfd166c396feea911ffafd09b 469 Gene3D G3DSA:1.10.10.10 398 469 3.2E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS09765 2a179a9bfd166c396feea911ffafd09b 469 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 232 468 6.0E-113 T 28-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 CFK41_RS09765 2a179a9bfd166c396feea911ffafd09b 469 Pfam PF04539 Sigma-70 region 3 315 391 3.4E-29 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS09765 2a179a9bfd166c396feea911ffafd09b 469 Pfam PF04545 Sigma-70, region 4 404 457 3.0E-18 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS09765 2a179a9bfd166c396feea911ffafd09b 469 SUPERFAMILY SSF88946 162 306 6.39E-51 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS09765 2a179a9bfd166c396feea911ffafd09b 469 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 260 273 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS09765 2a179a9bfd166c396feea911ffafd09b 469 PRINTS PR00046 Major sigma-70 factor signature 429 444 4.6E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS09765 2a179a9bfd166c396feea911ffafd09b 469 PRINTS PR00046 Major sigma-70 factor signature 444 455 4.6E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS09765 2a179a9bfd166c396feea911ffafd09b 469 PRINTS PR00046 Major sigma-70 factor signature 284 292 4.6E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS09765 2a179a9bfd166c396feea911ffafd09b 469 PRINTS PR00046 Major sigma-70 factor signature 408 420 4.6E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS09765 2a179a9bfd166c396feea911ffafd09b 469 PRINTS PR00046 Major sigma-70 factor signature 260 273 4.6E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS09765 2a179a9bfd166c396feea911ffafd09b 469 Pfam PF04542 Sigma-70 region 2 236 305 4.9E-22 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS09765 2a179a9bfd166c396feea911ffafd09b 469 SUPERFAMILY SSF88659 367 468 2.24E-27 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS09765 2a179a9bfd166c396feea911ffafd09b 469 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 232 457 2.7E-36 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS09765 2a179a9bfd166c396feea911ffafd09b 469 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 56 469 31.085 T 28-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 CFK41_RS09765 2a179a9bfd166c396feea911ffafd09b 469 SUPERFAMILY SSF88659 309 382 2.24E-21 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS09765 2a179a9bfd166c396feea911ffafd09b 469 Gene3D G3DSA:1.10.10.10 306 356 1.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS09765 2a179a9bfd166c396feea911ffafd09b 469 Pfam PF00140 Sigma-70 factor, region 1.2 165 198 5.1E-14 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS09765 2a179a9bfd166c396feea911ffafd09b 469 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 429 455 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS09765 2a179a9bfd166c396feea911ffafd09b 469 Gene3D G3DSA:1.10.601.10 108 305 5.5E-74 T 28-03-2018 CFK41_RS13675 807bc79070767ee40b4941a10ea5f381 178 Pfam PF13671 AAA domain 11 127 1.3E-8 T 28-03-2018 CFK41_RS13675 807bc79070767ee40b4941a10ea5f381 178 SUPERFAMILY SSF52540 8 171 6.8E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS13675 807bc79070767ee40b4941a10ea5f381 178 Gene3D G3DSA:3.40.50.300 6 175 3.2E-14 T 28-03-2018 CFK41_RS13545 ce94f609d870c0f62a0736c062c6074a 935 Pfam PF01565 FAD binding domain 28 164 2.7E-32 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CFK41_RS13545 ce94f609d870c0f62a0736c062c6074a 935 Pfam PF02913 FAD linked oxidases, C-terminal domain 253 499 2.6E-53 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CFK41_RS13545 ce94f609d870c0f62a0736c062c6074a 935 Pfam PF13183 4Fe-4S dicluster domain 522 595 2.2E-9 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CFK41_RS13545 ce94f609d870c0f62a0736c062c6074a 935 Gene3D G3DSA:1.10.1060.10 505 619 1.0E-15 T 28-03-2018 CFK41_RS13545 ce94f609d870c0f62a0736c062c6074a 935 Gene3D G3DSA:3.30.43.10 11 79 2.4E-12 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CFK41_RS13545 ce94f609d870c0f62a0736c062c6074a 935 Gene3D G3DSA:1.10.45.10 461 500 7.5E-11 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CFK41_RS13545 ce94f609d870c0f62a0736c062c6074a 935 SUPERFAMILY SSF55103 257 506 1.11E-47 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CFK41_RS13545 ce94f609d870c0f62a0736c062c6074a 935 Pfam PF02754 Cysteine-rich domain 834 914 0.004 T 28-03-2018 IPR004017 Cysteine-rich domain CFK41_RS13545 ce94f609d870c0f62a0736c062c6074a 935 Pfam PF02754 Cysteine-rich domain 724 796 0.016 T 28-03-2018 IPR004017 Cysteine-rich domain CFK41_RS13545 ce94f609d870c0f62a0736c062c6074a 935 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 525 536 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CFK41_RS13545 ce94f609d870c0f62a0736c062c6074a 935 SUPERFAMILY SSF46548 486 609 7.15E-18 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CFK41_RS13545 ce94f609d870c0f62a0736c062c6074a 935 SUPERFAMILY SSF56176 8 251 1.02E-47 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CFK41_RS13545 ce94f609d870c0f62a0736c062c6074a 935 Gene3D G3DSA:3.30.465.10 80 274 2.7E-28 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CFK41_RS13960 f27f0930fdba113c16a1fa06194e87c0 318 SUPERFAMILY SSF161098 77 302 2.35E-59 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS13960 f27f0930fdba113c16a1fa06194e87c0 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 306 5.2E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS13960 f27f0930fdba113c16a1fa06194e87c0 318 Gene3D G3DSA:1.20.58.370 23 63 8.2E-4 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CFK41_RS13960 f27f0930fdba113c16a1fa06194e87c0 318 Gene3D G3DSA:1.10.3720.10 81 312 4.0E-41 T 28-03-2018 CFK41_RS11675 b28958a1ff563682a6ac3b9b33bcb7c6 914 SUPERFAMILY SSF144010 678 908 3.66E-13 T 28-03-2018 CFK41_RS11675 b28958a1ff563682a6ac3b9b33bcb7c6 914 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 551 6.9E-124 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CFK41_RS11675 b28958a1ff563682a6ac3b9b33bcb7c6 914 Pfam PF13537 Glutamine amidotransferase domain 45 171 1.1E-44 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CFK41_RS11675 b28958a1ff563682a6ac3b9b33bcb7c6 914 SUPERFAMILY SSF56235 1 223 8.58E-57 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CFK41_RS11675 b28958a1ff563682a6ac3b9b33bcb7c6 914 Gene3D G3DSA:3.60.20.10 1 227 3.5E-50 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CFK41_RS11675 b28958a1ff563682a6ac3b9b33bcb7c6 914 Gene3D G3DSA:3.30.1330.100 672 913 2.3E-9 T 28-03-2018 CFK41_RS11675 b28958a1ff563682a6ac3b9b33bcb7c6 914 SUPERFAMILY SSF52402 245 405 5.58E-52 T 28-03-2018 CFK41_RS11675 b28958a1ff563682a6ac3b9b33bcb7c6 914 SUPERFAMILY SSF52402 470 608 5.58E-52 T 28-03-2018 CFK41_RS11675 b28958a1ff563682a6ac3b9b33bcb7c6 914 Gene3D G3DSA:3.40.50.620 232 621 7.9E-54 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS11675 b28958a1ff563682a6ac3b9b33bcb7c6 914 Pfam PF00733 Asparagine synthase 250 616 1.5E-68 T 28-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CFK41_RS01955 fd91a9cfea8481fc653d9f9efa6626c4 528 Pfam PF03806 AbgT putative transporter family 18 526 5.8E-145 T 28-03-2018 IPR004697 p-Aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 CFK41_RS14290 bee5cdbea2bf0440e977d533a7fc6af2 328 SUPERFAMILY SSF47413 2 58 4.69E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS14290 bee5cdbea2bf0440e977d533a7fc6af2 328 Pfam PF13377 Periplasmic binding protein-like domain 163 325 1.1E-29 T 28-03-2018 CFK41_RS14290 bee5cdbea2bf0440e977d533a7fc6af2 328 SUPERFAMILY SSF53822 59 326 2.08E-57 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS14290 bee5cdbea2bf0440e977d533a7fc6af2 328 Gene3D G3DSA:3.40.50.2300 57 160 2.0E-29 T 28-03-2018 CFK41_RS14290 bee5cdbea2bf0440e977d533a7fc6af2 328 Gene3D G3DSA:1.10.260.40 3 56 1.1E-11 T 28-03-2018 CFK41_RS14290 bee5cdbea2bf0440e977d533a7fc6af2 328 Gene3D G3DSA:3.40.50.2300 161 328 1.1E-44 T 28-03-2018 CFK41_RS14290 bee5cdbea2bf0440e977d533a7fc6af2 328 SMART SM00354 1 70 2.4E-7 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS13740 d8b5ebea44048d98d4ee50c13e0fb1be 309 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS13740 d8b5ebea44048d98d4ee50c13e0fb1be 309 Gene3D G3DSA:3.40.50.300 7 272 5.5E-59 T 28-03-2018 CFK41_RS13740 d8b5ebea44048d98d4ee50c13e0fb1be 309 SUPERFAMILY SSF52540 9 223 2.11E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS13740 d8b5ebea44048d98d4ee50c13e0fb1be 309 Pfam PF00005 ABC transporter 26 162 7.6E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS13740 d8b5ebea44048d98d4ee50c13e0fb1be 309 SMART SM00382 35 210 1.0E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS08025 3f00584390bf44416d6edf151f7787fe 202 Gene3D G3DSA:3.30.60.20 145 199 6.5E-15 T 28-03-2018 CFK41_RS08025 3f00584390bf44416d6edf151f7787fe 202 Gene3D G3DSA:3.40.50.300 2 144 9.6E-39 T 28-03-2018 CFK41_RS08025 3f00584390bf44416d6edf151f7787fe 202 Pfam PF00265 Thymidine kinase 2 189 1.3E-33 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CFK41_RS08025 3f00584390bf44416d6edf151f7787fe 202 SUPERFAMILY SSF52540 1 144 1.5E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS08025 3f00584390bf44416d6edf151f7787fe 202 PIRSF PIRSF035805 1 198 3.4E-46 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CFK41_RS08025 3f00584390bf44416d6edf151f7787fe 202 SUPERFAMILY SSF57716 146 192 5.7E-7 T 28-03-2018 CFK41_RS15320 e1dec05a243f226169a2231a3637715e 155 Gene3D G3DSA:3.90.79.10 1 144 1.6E-19 T 28-03-2018 CFK41_RS15320 e1dec05a243f226169a2231a3637715e 155 SUPERFAMILY SSF55811 2 139 2.98E-20 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CFK41_RS15320 e1dec05a243f226169a2231a3637715e 155 Pfam PF00293 NUDIX domain 4 130 1.2E-11 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CFK41_RS06525 9d6130900bb70191b2b7b9e647c02a97 675 SUPERFAMILY SSF52279 464 673 1.31E-11 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CFK41_RS06525 9d6130900bb70191b2b7b9e647c02a97 675 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 128 421 1.8E-32 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS06525 9d6130900bb70191b2b7b9e647c02a97 675 Gene3D G3DSA:3.20.20.300 30 447 9.9E-83 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS06525 9d6130900bb70191b2b7b9e647c02a97 675 Gene3D G3DSA:3.40.50.1700 449 674 5.6E-15 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CFK41_RS06525 9d6130900bb70191b2b7b9e647c02a97 675 SUPERFAMILY SSF51445 31 68 1.9E-65 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS06525 9d6130900bb70191b2b7b9e647c02a97 675 SUPERFAMILY SSF51445 105 463 1.9E-65 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS06525 9d6130900bb70191b2b7b9e647c02a97 675 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 464 672 2.7E-7 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CFK41_RS00835 a68583bbfe066b62d36d8340c21f2024 437 SUPERFAMILY SSF103473 1 407 9.68E-66 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS00835 a68583bbfe066b62d36d8340c21f2024 437 Gene3D G3DSA:1.20.1250.20 3 201 1.8E-24 T 28-03-2018 CFK41_RS00835 a68583bbfe066b62d36d8340c21f2024 437 Gene3D G3DSA:1.20.1250.20 202 420 3.7E-22 T 28-03-2018 CFK41_RS00835 a68583bbfe066b62d36d8340c21f2024 437 ProSitePatterns PS00217 Sugar transport proteins signature 2. 103 128 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CFK41_RS00835 a68583bbfe066b62d36d8340c21f2024 437 Pfam PF07690 Major Facilitator Superfamily 16 366 5.2E-31 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS13785 6af9e98dba08c687e79d6a487b54f930 406 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 336 376 1.9E-9 T 28-03-2018 IPR011964 YVTN beta-propeller repeat CFK41_RS13785 6af9e98dba08c687e79d6a487b54f930 406 Gene3D G3DSA:2.130.10.10 39 236 1.4E-18 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CFK41_RS13785 6af9e98dba08c687e79d6a487b54f930 406 SUPERFAMILY SSF51004 98 398 2.14E-47 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain CFK41_RS13785 6af9e98dba08c687e79d6a487b54f930 406 Gene3D G3DSA:2.130.10.10 237 294 4.7E-12 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CFK41_RS13785 6af9e98dba08c687e79d6a487b54f930 406 Gene3D G3DSA:2.130.10.10 295 404 8.2E-23 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CFK41_RS13785 6af9e98dba08c687e79d6a487b54f930 406 Pfam PF10282 Lactonase, 7-bladed beta-propeller 312 403 3.5E-6 T 28-03-2018 IPR019405 Lactonase, 7-bladed beta propeller CFK41_RS03075 c923316a6fa5d1880eb354c343491359 292 Gene3D G3DSA:1.10.3720.10 46 291 1.1E-24 T 28-03-2018 CFK41_RS03075 c923316a6fa5d1880eb354c343491359 292 SUPERFAMILY SSF161098 94 275 2.75E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS03075 c923316a6fa5d1880eb354c343491359 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 287 8.0E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS13195 eadf6673e788908e0023371a1c88e133 746 PIRSF PIRSF005536 17 692 3.1E-165 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CFK41_RS13195 eadf6673e788908e0023371a1c88e133 746 Gene3D G3DSA:3.20.20.70 308 625 6.4E-45 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS13195 eadf6673e788908e0023371a1c88e133 746 SUPERFAMILY SSF51445 322 655 3.09E-89 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS13195 eadf6673e788908e0023371a1c88e133 746 Pfam PF02065 Melibiase 290 627 1.7E-109 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CFK41_RS13195 eadf6673e788908e0023371a1c88e133 746 PRINTS PR00743 Glycosyl hydrolase family 36 signature 326 340 5.1E-36 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CFK41_RS13195 eadf6673e788908e0023371a1c88e133 746 PRINTS PR00743 Glycosyl hydrolase family 36 signature 241 256 5.1E-36 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CFK41_RS13195 eadf6673e788908e0023371a1c88e133 746 PRINTS PR00743 Glycosyl hydrolase family 36 signature 354 369 5.1E-36 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CFK41_RS13195 eadf6673e788908e0023371a1c88e133 746 PRINTS PR00743 Glycosyl hydrolase family 36 signature 513 529 5.1E-36 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CFK41_RS13195 eadf6673e788908e0023371a1c88e133 746 PRINTS PR00743 Glycosyl hydrolase family 36 signature 404 426 5.1E-36 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CFK41_RS13195 eadf6673e788908e0023371a1c88e133 746 PRINTS PR00743 Glycosyl hydrolase family 36 signature 463 478 5.1E-36 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CFK41_RS13195 eadf6673e788908e0023371a1c88e133 746 PRINTS PR00743 Glycosyl hydrolase family 36 signature 538 554 5.1E-36 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CFK41_RS13195 eadf6673e788908e0023371a1c88e133 746 Gene3D G3DSA:2.60.40.1180 627 742 2.4E-14 T 28-03-2018 CFK41_RS13195 eadf6673e788908e0023371a1c88e133 746 Gene3D G3DSA:2.70.98.60 16 307 4.5E-65 T 28-03-2018 CFK41_RS13195 eadf6673e788908e0023371a1c88e133 746 Pfam PF16874 Glycosyl hydrolase family 36 C-terminal domain 645 727 1.4E-8 T 28-03-2018 IPR031705 Glycosyl hydrolase family 36, C-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CFK41_RS13195 eadf6673e788908e0023371a1c88e133 746 Pfam PF16875 Glycosyl hydrolase family 36 N-terminal domain 42 284 1.2E-47 T 28-03-2018 IPR031704 Glycosyl hydrolase family 36, N-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CFK41_RS13195 eadf6673e788908e0023371a1c88e133 746 ProSitePatterns PS00512 Alpha-galactosidase signature. 355 371 - T 28-03-2018 IPR000111 Glycoside hydrolase family 27/36, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CFK41_RS15805 ce028bad6463f219db96b1b2328075e6 151 SUPERFAMILY SSF52374 2 134 3.22E-23 T 28-03-2018 CFK41_RS15805 ce028bad6463f219db96b1b2328075e6 151 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 67 1.0E-15 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CFK41_RS15805 ce028bad6463f219db96b1b2328075e6 151 Pfam PF01467 Cytidylyltransferase-like 5 131 8.4E-13 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CFK41_RS15805 ce028bad6463f219db96b1b2328075e6 151 Gene3D G3DSA:3.40.50.620 1 138 4.8E-26 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS03270 f1f03c18e7c151209d4cf150b96cd230 331 Pfam PF01032 FecCD transport family 16 324 3.7E-84 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CFK41_RS03270 f1f03c18e7c151209d4cf150b96cd230 331 SUPERFAMILY SSF81345 3 324 5.62E-72 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CFK41_RS03270 f1f03c18e7c151209d4cf150b96cd230 331 Gene3D G3DSA:1.10.3470.10 1 331 5.2E-60 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CFK41_RS08955 405333eb522cf9cfe142ee425d2f3d85 379 Gene3D G3DSA:3.40.50.720 2 155 5.5E-35 T 28-03-2018 CFK41_RS08955 405333eb522cf9cfe142ee425d2f3d85 379 SUPERFAMILY SSF51735 5 169 4.18E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS08955 405333eb522cf9cfe142ee425d2f3d85 379 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 149 260 9.3E-13 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CFK41_RS08955 405333eb522cf9cfe142ee425d2f3d85 379 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 10 126 3.2E-22 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS08955 405333eb522cf9cfe142ee425d2f3d85 379 SUPERFAMILY SSF55347 143 303 5.89E-38 T 28-03-2018 CFK41_RS08955 405333eb522cf9cfe142ee425d2f3d85 379 Gene3D G3DSA:3.30.360.10 156 379 7.7E-52 T 28-03-2018 CFK41_RS01300 43463a1215194587119f29da08e85b4a 308 SUPERFAMILY SSF161098 34 308 1.7E-74 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01300 43463a1215194587119f29da08e85b4a 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 124 301 1.9E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01300 43463a1215194587119f29da08e85b4a 308 Gene3D G3DSA:1.10.3720.10 40 300 1.3E-45 T 28-03-2018 CFK41_RS16645 4f43a25cf4d1ea815dab444ecea57c3c 483 Pfam PF16347 Domain of unknown function (DUF4976) 356 466 3.8E-18 T 28-03-2018 IPR032506 Domain of unknown function DUF4976 Reactome: R-HSA-2024096 CFK41_RS16645 4f43a25cf4d1ea815dab444ecea57c3c 483 SUPERFAMILY SSF53649 3 467 1.74E-124 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CFK41_RS16645 4f43a25cf4d1ea815dab444ecea57c3c 483 Pfam PF00884 Sulfatase 4 348 3.8E-65 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CFK41_RS16645 4f43a25cf4d1ea815dab444ecea57c3c 483 Gene3D G3DSA:3.40.720.10 307 377 1.0E-10 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CFK41_RS16645 4f43a25cf4d1ea815dab444ecea57c3c 483 Gene3D G3DSA:3.40.720.10 1 306 1.3E-93 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CFK41_RS16645 4f43a25cf4d1ea815dab444ecea57c3c 483 Gene3D G3DSA:3.30.1120.10 378 479 5.4E-16 T 28-03-2018 CFK41_RS16645 4f43a25cf4d1ea815dab444ecea57c3c 483 ProSitePatterns PS00523 Sulfatases signature 1. 50 62 - T 28-03-2018 IPR024607 Sulfatase, conserved site CFK41_RS14355 1513597562bed05781a0ed825ca30811 287 SUPERFAMILY SSF161098 41 268 3.66E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS14355 1513597562bed05781a0ed825ca30811 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 250 2.2E-11 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS14355 1513597562bed05781a0ed825ca30811 287 Gene3D G3DSA:1.10.3720.10 1 282 1.9E-37 T 28-03-2018 CFK41_RS07355 28cf61898644c9cc98a96efc7ae76cc6 479 Gene3D G3DSA:3.30.499.10 1 154 4.3E-38 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS07355 28cf61898644c9cc98a96efc7ae76cc6 479 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 467 58.263 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CFK41_RS07355 28cf61898644c9cc98a96efc7ae76cc6 479 Gene3D G3DSA:3.40.1060.10 155 289 3.6E-43 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS07355 28cf61898644c9cc98a96efc7ae76cc6 479 SUPERFAMILY SSF53732 3 466 2.22E-158 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS07355 28cf61898644c9cc98a96efc7ae76cc6 479 Pfam PF00330 Aconitase family (aconitate hydratase) 7 458 1.6E-151 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS07355 28cf61898644c9cc98a96efc7ae76cc6 479 ProSitePatterns PS01244 Aconitase family signature 2. 400 413 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CFK41_RS07355 28cf61898644c9cc98a96efc7ae76cc6 479 PRINTS PR00415 Aconitase family signature 210 223 8.7E-49 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS07355 28cf61898644c9cc98a96efc7ae76cc6 479 PRINTS PR00415 Aconitase family signature 344 355 8.7E-49 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS07355 28cf61898644c9cc98a96efc7ae76cc6 479 PRINTS PR00415 Aconitase family signature 83 96 8.7E-49 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS07355 28cf61898644c9cc98a96efc7ae76cc6 479 PRINTS PR00415 Aconitase family signature 134 149 8.7E-49 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS07355 28cf61898644c9cc98a96efc7ae76cc6 479 PRINTS PR00415 Aconitase family signature 196 209 8.7E-49 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS07355 28cf61898644c9cc98a96efc7ae76cc6 479 PRINTS PR00415 Aconitase family signature 287 301 8.7E-49 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS07355 28cf61898644c9cc98a96efc7ae76cc6 479 PRINTS PR00415 Aconitase family signature 120 133 8.7E-49 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS07355 28cf61898644c9cc98a96efc7ae76cc6 479 PRINTS PR00415 Aconitase family signature 400 413 8.7E-49 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS07355 28cf61898644c9cc98a96efc7ae76cc6 479 PRINTS PR00415 Aconitase family signature 109 117 8.7E-49 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS07355 28cf61898644c9cc98a96efc7ae76cc6 479 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 460 2.5E-218 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CFK41_RS07355 28cf61898644c9cc98a96efc7ae76cc6 479 Gene3D G3DSA:3.30.499.10 325 477 2.0E-49 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CFK41_RS09425 03faf176c5689ad7d13948f4b0c5936d 108 Gene3D G3DSA:1.10.720.10 74 108 7.5E-7 T 28-03-2018 CFK41_RS07500 e5f2fb4c5ac849906d3eff82a90ee55c 556 SUPERFAMILY SSF90123 13 333 4.19E-45 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS07500 e5f2fb4c5ac849906d3eff82a90ee55c 556 Gene3D G3DSA:3.40.50.300 328 556 5.5E-49 T 28-03-2018 CFK41_RS07500 e5f2fb4c5ac849906d3eff82a90ee55c 556 SMART SM00382 366 556 7.3E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS07500 e5f2fb4c5ac849906d3eff82a90ee55c 556 ProSitePatterns PS00211 ABC transporters family signature. 481 495 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS07500 e5f2fb4c5ac849906d3eff82a90ee55c 556 SUPERFAMILY SSF52540 335 556 1.9E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS07500 e5f2fb4c5ac849906d3eff82a90ee55c 556 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 23 549 1.6E-151 T 28-03-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 CFK41_RS07500 e5f2fb4c5ac849906d3eff82a90ee55c 556 Pfam PF00005 ABC transporter 361 509 4.7E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS07500 e5f2fb4c5ac849906d3eff82a90ee55c 556 Gene3D G3DSA:1.20.1560.10 14 327 1.3E-33 T 28-03-2018 CFK41_RS07500 e5f2fb4c5ac849906d3eff82a90ee55c 556 Pfam PF00664 ABC transporter transmembrane region 33 281 3.8E-17 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS07860 ec1944ad2414e90d45393087a8cd7d12 355 Gene3D G3DSA:3.40.50.1980 35 167 4.4E-23 T 28-03-2018 CFK41_RS07860 ec1944ad2414e90d45393087a8cd7d12 355 Gene3D G3DSA:3.40.50.1980 179 346 6.7E-22 T 28-03-2018 CFK41_RS07860 ec1944ad2414e90d45393087a8cd7d12 355 SUPERFAMILY SSF53807 45 345 2.28E-39 T 28-03-2018 CFK41_RS07860 ec1944ad2414e90d45393087a8cd7d12 355 Pfam PF01497 Periplasmic binding protein 61 294 1.1E-21 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CFK41_RS14710 bf8c070c3bd107e93d1dd2d06454ee05 254 Pfam PF07090 Putative glutamine amidotransferase 3 246 1.2E-91 T 28-03-2018 IPR010768 Putative glutamine amidotransferase CFK41_RS14710 bf8c070c3bd107e93d1dd2d06454ee05 254 Gene3D G3DSA:3.40.50.880 1 248 8.2E-46 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS14710 bf8c070c3bd107e93d1dd2d06454ee05 254 SUPERFAMILY SSF52317 3 246 1.3E-62 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS00380 940095a76f4bb5dfddc313ee7cefbb06 382 Gene3D G3DSA:3.90.1200.10 181 365 2.0E-18 T 28-03-2018 CFK41_RS00380 940095a76f4bb5dfddc313ee7cefbb06 382 Pfam PF01636 Phosphotransferase enzyme family 119 333 2.4E-19 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CFK41_RS00380 940095a76f4bb5dfddc313ee7cefbb06 382 SUPERFAMILY SSF56112 88 334 2.6E-31 T 28-03-2018 IPR011009 Protein kinase-like domain CFK41_RS00380 940095a76f4bb5dfddc313ee7cefbb06 382 Gene3D G3DSA:3.30.200.20 86 176 0.0025 T 28-03-2018 CFK41_RS09630 41722174320b97fde9a9e71ad0da0f76 651 SMART SM00861 340 504 5.8E-37 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CFK41_RS09630 41722174320b97fde9a9e71ad0da0f76 651 Gene3D G3DSA:3.40.50.970 60 319 6.7E-57 T 28-03-2018 CFK41_RS09630 41722174320b97fde9a9e71ad0da0f76 651 Pfam PF02779 Transketolase, pyrimidine binding domain 341 501 6.8E-26 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CFK41_RS09630 41722174320b97fde9a9e71ad0da0f76 651 ProSitePatterns PS00802 Transketolase signature 2. 446 462 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CFK41_RS09630 41722174320b97fde9a9e71ad0da0f76 651 SUPERFAMILY SSF52922 526 650 1.83E-14 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CFK41_RS09630 41722174320b97fde9a9e71ad0da0f76 651 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 66 251 1.4E-68 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CFK41_RS09630 41722174320b97fde9a9e71ad0da0f76 651 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 258 303 2.2E-5 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CFK41_RS09630 41722174320b97fde9a9e71ad0da0f76 651 SUPERFAMILY SSF52518 79 386 3.33E-47 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CFK41_RS09630 41722174320b97fde9a9e71ad0da0f76 651 Gene3D G3DSA:3.40.50.970 320 510 7.9E-40 T 28-03-2018 CFK41_RS09630 41722174320b97fde9a9e71ad0da0f76 651 Gene3D G3DSA:3.40.50.920 517 651 3.4E-17 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CFK41_RS09630 41722174320b97fde9a9e71ad0da0f76 651 ProSitePatterns PS00801 Transketolase signature 1. 85 104 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CFK41_RS09630 41722174320b97fde9a9e71ad0da0f76 651 Pfam PF02780 Transketolase, C-terminal domain 526 642 1.8E-13 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CFK41_RS09630 41722174320b97fde9a9e71ad0da0f76 651 SUPERFAMILY SSF52518 317 502 8.16E-43 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CFK41_RS05240 6a4e030735ffe9e8607f40bcb135fbe8 239 SUPERFAMILY SSF54593 132 232 4.93E-7 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS05240 6a4e030735ffe9e8607f40bcb135fbe8 239 Gene3D G3DSA:3.10.180.10 2 123 1.4E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS05240 6a4e030735ffe9e8607f40bcb135fbe8 239 Gene3D G3DSA:3.10.180.10 127 238 2.9E-10 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS05240 6a4e030735ffe9e8607f40bcb135fbe8 239 SUPERFAMILY SSF54593 4 118 4.23E-12 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS16935 068513d2f3e71fc193b1829187ba5ee9 636 SUPERFAMILY SSF52518 11 224 4.61E-30 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CFK41_RS16935 068513d2f3e71fc193b1829187ba5ee9 636 SUPERFAMILY SSF52518 411 622 1.09E-44 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CFK41_RS16935 068513d2f3e71fc193b1829187ba5ee9 636 Gene3D G3DSA:3.40.50.1220 229 387 9.5E-42 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CFK41_RS16935 068513d2f3e71fc193b1829187ba5ee9 636 Gene3D G3DSA:3.40.50.970 388 600 6.4E-36 T 28-03-2018 CFK41_RS16935 068513d2f3e71fc193b1829187ba5ee9 636 TIGRFAM TIGR04377 myo_inos_iolD: 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase 13 633 1.8E-262 T 28-03-2018 IPR030817 3,5/4-Trihydroxycyclohexa-1,2-dione hydrolase GO:0016823|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 CFK41_RS16935 068513d2f3e71fc193b1829187ba5ee9 636 Gene3D G3DSA:3.40.50.970 8 228 1.1E-43 T 28-03-2018 CFK41_RS16935 068513d2f3e71fc193b1829187ba5ee9 636 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 234 368 3.7E-34 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CFK41_RS16935 068513d2f3e71fc193b1829187ba5ee9 636 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 431 589 5.1E-36 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CFK41_RS16935 068513d2f3e71fc193b1829187ba5ee9 636 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 15 213 7.2E-34 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CFK41_RS16935 068513d2f3e71fc193b1829187ba5ee9 636 SUPERFAMILY SSF52467 200 378 3.07E-44 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CFK41_RS00665 dd098dd2aee9ff7bbfa5e324bf2c3102 302 Gene3D G3DSA:3.40.50.1820 3 293 1.3E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS00665 dd098dd2aee9ff7bbfa5e324bf2c3102 302 Pfam PF00561 alpha/beta hydrolase fold 30 277 5.5E-21 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CFK41_RS00665 dd098dd2aee9ff7bbfa5e324bf2c3102 302 SUPERFAMILY SSF53474 9 291 1.25E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS00665 dd098dd2aee9ff7bbfa5e324bf2c3102 302 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 32 40 2.0E-9 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CFK41_RS00665 dd098dd2aee9ff7bbfa5e324bf2c3102 302 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 112 126 2.0E-9 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CFK41_RS00665 dd098dd2aee9ff7bbfa5e324bf2c3102 302 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 58 69 2.0E-9 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CFK41_RS14585 b7474835e3165119146bf4b4e86f087d 316 Gene3D G3DSA:3.40.1190.20 10 307 1.3E-55 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS14585 b7474835e3165119146bf4b4e86f087d 316 Pfam PF00294 pfkB family carbohydrate kinase 12 299 9.6E-46 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CFK41_RS14585 b7474835e3165119146bf4b4e86f087d 316 SUPERFAMILY SSF53613 10 299 1.18E-65 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS13210 947db3b3c3163a2c7f80f324601147d8 461 SUPERFAMILY SSF53850 35 459 8.51E-54 T 28-03-2018 CFK41_RS13210 947db3b3c3163a2c7f80f324601147d8 461 Gene3D G3DSA:3.40.190.10 33 211 3.1E-25 T 28-03-2018 CFK41_RS13210 947db3b3c3163a2c7f80f324601147d8 461 Gene3D G3DSA:3.40.190.10 249 413 1.9E-10 T 28-03-2018 CFK41_RS13210 947db3b3c3163a2c7f80f324601147d8 461 Pfam PF13416 Bacterial extracellular solute-binding protein 66 389 1.5E-23 T 28-03-2018 CFK41_RS12435 8d39fe417212fedcdf5e2364096986d3 494 SUPERFAMILY SSF56235 23 279 7.55E-66 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CFK41_RS12435 8d39fe417212fedcdf5e2364096986d3 494 Pfam PF13522 Glutamine amidotransferase domain 83 221 1.1E-17 T 28-03-2018 CFK41_RS12435 8d39fe417212fedcdf5e2364096986d3 494 Pfam PF00156 Phosphoribosyl transferase domain 291 397 5.7E-7 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CFK41_RS12435 8d39fe417212fedcdf5e2364096986d3 494 Gene3D G3DSA:3.60.20.10 174 245 1.5E-22 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CFK41_RS12435 8d39fe417212fedcdf5e2364096986d3 494 Gene3D G3DSA:3.60.20.10 27 173 6.3E-38 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CFK41_RS12435 8d39fe417212fedcdf5e2364096986d3 494 SUPERFAMILY SSF53271 262 474 2.15E-67 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CFK41_RS12435 8d39fe417212fedcdf5e2364096986d3 494 PIRSF PIRSF000485 19 479 2.3E-158 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CFK41_RS12435 8d39fe417212fedcdf5e2364096986d3 494 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 23 468 2.5E-157 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CFK41_RS12435 8d39fe417212fedcdf5e2364096986d3 494 Gene3D G3DSA:3.40.50.2020 246 453 4.2E-31 T 28-03-2018 CFK41_RS12435 8d39fe417212fedcdf5e2364096986d3 494 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 22 467 45.783 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CFK41_RS02090 5087aa557a6d23eac75381bf774bedc7 159 PIRSF PIRSF009151 31 159 6.0E-52 T 28-03-2018 IPR008497 Protein of unknown function DUF779 CFK41_RS02090 5087aa557a6d23eac75381bf774bedc7 159 Pfam PF05610 Protein of unknown function (DUF779) 55 156 3.9E-44 T 28-03-2018 IPR008497 Protein of unknown function DUF779 CFK41_RS04685 3eeab14be78b1c36ba148889ed0b67bb 434 Hamap MF_01465 Protein translocase subunit SecY [secY]. 4 433 27.689 T 28-03-2018 IPR026593 Protein translocase subunit SecY CFK41_RS04685 3eeab14be78b1c36ba148889ed0b67bb 434 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 14 428 3.2E-125 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CFK41_RS04685 3eeab14be78b1c36ba148889ed0b67bb 434 SUPERFAMILY SSF103491 2 423 1.83E-116 T 28-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CFK41_RS04685 3eeab14be78b1c36ba148889ed0b67bb 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 269 288 1.8E-96 T 28-03-2018 CFK41_RS04685 3eeab14be78b1c36ba148889ed0b67bb 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 368 386 1.8E-96 T 28-03-2018 CFK41_RS04685 3eeab14be78b1c36ba148889ed0b67bb 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 156 181 1.8E-96 T 28-03-2018 CFK41_RS04685 3eeab14be78b1c36ba148889ed0b67bb 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 182 205 1.8E-96 T 28-03-2018 CFK41_RS04685 3eeab14be78b1c36ba148889ed0b67bb 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 73 93 1.8E-96 T 28-03-2018 CFK41_RS04685 3eeab14be78b1c36ba148889ed0b67bb 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 114 137 1.8E-96 T 28-03-2018 CFK41_RS04685 3eeab14be78b1c36ba148889ed0b67bb 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 17 35 1.8E-96 T 28-03-2018 CFK41_RS04685 3eeab14be78b1c36ba148889ed0b67bb 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 402 420 1.8E-96 T 28-03-2018 CFK41_RS04685 3eeab14be78b1c36ba148889ed0b67bb 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 313 335 1.8E-96 T 28-03-2018 CFK41_RS04685 3eeab14be78b1c36ba148889ed0b67bb 434 Gene3D G3DSA:1.10.3370.10 1 434 1.9E-145 T 28-03-2018 CFK41_RS04685 3eeab14be78b1c36ba148889ed0b67bb 434 ProSitePatterns PS00755 Protein secY signature 1. 74 93 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CFK41_RS04685 3eeab14be78b1c36ba148889ed0b67bb 434 PIRSF PIRSF004557 1 434 8.9E-116 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CFK41_RS04685 3eeab14be78b1c36ba148889ed0b67bb 434 Pfam PF00344 SecY translocase 74 417 6.1E-108 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CFK41_RS16295 cc40e4446bd2f858a4fa7c530c3fab97 993 SUPERFAMILY SSF51445 26 373 2.42E-53 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS16295 cc40e4446bd2f858a4fa7c530c3fab97 993 Pfam PF14310 Fibronectin type III-like domain 772 849 8.3E-9 T 28-03-2018 IPR026891 Fibronectin type III-like domain CFK41_RS16295 cc40e4446bd2f858a4fa7c530c3fab97 993 Gene3D G3DSA:3.40.50.1700 367 735 1.5E-33 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CFK41_RS16295 cc40e4446bd2f858a4fa7c530c3fab97 993 SMART SM01217 772 849 1.8E-6 T 28-03-2018 IPR026891 Fibronectin type III-like domain CFK41_RS16295 cc40e4446bd2f858a4fa7c530c3fab97 993 SUPERFAMILY SSF52279 381 439 1.7E-20 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CFK41_RS16295 cc40e4446bd2f858a4fa7c530c3fab97 993 SUPERFAMILY SSF52279 591 733 1.7E-20 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CFK41_RS16295 cc40e4446bd2f858a4fa7c530c3fab97 993 PRINTS PR00133 Glycosyl hydrolase family 3 signature 79 98 2.4E-5 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS16295 cc40e4446bd2f858a4fa7c530c3fab97 993 PRINTS PR00133 Glycosyl hydrolase family 3 signature 166 182 2.4E-5 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS16295 cc40e4446bd2f858a4fa7c530c3fab97 993 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 53 317 1.1E-29 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS16295 cc40e4446bd2f858a4fa7c530c3fab97 993 Gene3D G3DSA:2.60.40.10 749 862 1.9E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS16295 cc40e4446bd2f858a4fa7c530c3fab97 993 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 375 733 2.3E-27 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CFK41_RS16295 cc40e4446bd2f858a4fa7c530c3fab97 993 Gene3D G3DSA:3.20.20.300 11 366 2.4E-62 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS02210 eab1c3469a2e90aeec7352e995564898 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 216 1.5E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02210 eab1c3469a2e90aeec7352e995564898 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 1.5E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02210 eab1c3469a2e90aeec7352e995564898 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 1.5E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02210 eab1c3469a2e90aeec7352e995564898 313 Gene3D G3DSA:3.40.50.720 2 313 3.6E-48 T 28-03-2018 CFK41_RS02210 eab1c3469a2e90aeec7352e995564898 313 SUPERFAMILY SSF51735 13 262 5.6E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS02210 eab1c3469a2e90aeec7352e995564898 313 Pfam PF00106 short chain dehydrogenase 18 215 6.6E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS05765 3f39226d852acc89e3f8cf6febe76acb 373 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 259 343 1.1E-21 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CFK41_RS05765 3f39226d852acc89e3f8cf6febe76acb 373 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 261 325 5.6E-15 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CFK41_RS05765 3f39226d852acc89e3f8cf6febe76acb 373 SUPERFAMILY SSF52540 26 281 7.41E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS05765 3f39226d852acc89e3f8cf6febe76acb 373 SMART SM00382 55 259 4.9E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS05765 3f39226d852acc89e3f8cf6febe76acb 373 Gene3D G3DSA:3.40.50.300 23 360 7.6E-67 T 28-03-2018 CFK41_RS05765 3f39226d852acc89e3f8cf6febe76acb 373 Pfam PF00005 ABC transporter 47 209 6.1E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS05765 3f39226d852acc89e3f8cf6febe76acb 373 ProSitePatterns PS00211 ABC transporters family signature. 182 196 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS03215 cb19031991e03c7ad551f9946e5fd6d1 427 Gene3D G3DSA:3.20.20.105 8 427 7.0E-131 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CFK41_RS03215 cb19031991e03c7ad551f9946e5fd6d1 427 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 17 421 44.349 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CFK41_RS03215 cb19031991e03c7ad551f9946e5fd6d1 427 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 25 419 9.1E-122 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CFK41_RS03215 cb19031991e03c7ad551f9946e5fd6d1 427 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 19 420 7.5E-117 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CFK41_RS03215 cb19031991e03c7ad551f9946e5fd6d1 427 SUPERFAMILY SSF51713 149 422 1.05E-123 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CFK41_RS03215 cb19031991e03c7ad551f9946e5fd6d1 427 SUPERFAMILY SSF51713 19 116 1.05E-123 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CFK41_RS03215 cb19031991e03c7ad551f9946e5fd6d1 427 Pfam PF01702 Queuine tRNA-ribosyltransferase 176 417 1.0E-73 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CFK41_RS07585 1e98814a1ea59ab1764b3b26e0e3b6e8 338 Gene3D G3DSA:3.20.20.70 1 338 1.0E-44 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS07585 1e98814a1ea59ab1764b3b26e0e3b6e8 338 Pfam PF03060 Nitronate monooxygenase 9 336 1.3E-67 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CFK41_RS07585 1e98814a1ea59ab1764b3b26e0e3b6e8 338 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 205 225 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CFK41_RS07585 1e98814a1ea59ab1764b3b26e0e3b6e8 338 SUPERFAMILY SSF51412 3 337 5.65E-49 T 28-03-2018 CFK41_RS14020 9b7e4f7094ed34187a6c7b043dc6ffbc 357 Gene3D G3DSA:3.40.50.2300 194 356 7.0E-12 T 28-03-2018 CFK41_RS14020 9b7e4f7094ed34187a6c7b043dc6ffbc 357 ProSitePatterns PS00356 LacI-type HTH domain signature. 23 41 - T 28-03-2018 CFK41_RS14020 9b7e4f7094ed34187a6c7b043dc6ffbc 357 SUPERFAMILY SSF47413 20 81 4.59E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS14020 9b7e4f7094ed34187a6c7b043dc6ffbc 357 Gene3D G3DSA:3.40.50.2300 77 193 1.5E-10 T 28-03-2018 CFK41_RS14020 9b7e4f7094ed34187a6c7b043dc6ffbc 357 Pfam PF00356 Bacterial regulatory proteins, lacI family 22 71 9.3E-14 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS14020 9b7e4f7094ed34187a6c7b043dc6ffbc 357 Pfam PF13377 Periplasmic binding protein-like domain 193 309 1.2E-10 T 28-03-2018 CFK41_RS14020 9b7e4f7094ed34187a6c7b043dc6ffbc 357 SMART SM00354 20 94 2.1E-17 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS14020 9b7e4f7094ed34187a6c7b043dc6ffbc 357 SUPERFAMILY SSF53822 85 321 3.66E-17 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS14020 9b7e4f7094ed34187a6c7b043dc6ffbc 357 Gene3D G3DSA:1.10.260.40 21 76 3.2E-19 T 28-03-2018 CFK41_RS05120 7a0c1dd685e19cea1b26cf309f0e8b6b 107 SUPERFAMILY SSF47413 18 101 1.21E-26 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS05120 7a0c1dd685e19cea1b26cf309f0e8b6b 107 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 17 88 1.2E-29 T 28-03-2018 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 CFK41_RS05120 7a0c1dd685e19cea1b26cf309f0e8b6b 107 Gene3D G3DSA:1.10.260.40 1 105 1.1E-14 T 28-03-2018 CFK41_RS05120 7a0c1dd685e19cea1b26cf309f0e8b6b 107 SMART SM00530 22 78 2.8E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CFK41_RS05120 7a0c1dd685e19cea1b26cf309f0e8b6b 107 Pfam PF01381 Helix-turn-helix 31 77 2.6E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CFK41_RS03755 277ee7247959bcde358a3749565bf7b0 431 SUPERFAMILY SSF53383 7 427 5.11E-113 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS03755 277ee7247959bcde358a3749565bf7b0 431 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 7 428 2.0E-188 T 28-03-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 CFK41_RS03755 277ee7247959bcde358a3749565bf7b0 431 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 202 216 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CFK41_RS03755 277ee7247959bcde358a3749565bf7b0 431 PIRSF PIRSF001434 1 431 8.7E-122 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CFK41_RS03755 277ee7247959bcde358a3749565bf7b0 431 Gene3D G3DSA:3.40.640.10 6 294 1.3E-54 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS03755 277ee7247959bcde358a3749565bf7b0 431 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 9 428 2.9E-128 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CFK41_RS03755 277ee7247959bcde358a3749565bf7b0 431 Gene3D G3DSA:3.90.1150.10 296 431 9.3E-45 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS14665 2c4ed7f90d37049646a27765fb1b72a7 373 Gene3D G3DSA:3.30.420.40 265 350 1.0E-9 T 28-03-2018 CFK41_RS14665 2c4ed7f90d37049646a27765fb1b72a7 373 Pfam PF00480 ROK family 159 262 2.8E-22 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CFK41_RS14665 2c4ed7f90d37049646a27765fb1b72a7 373 SUPERFAMILY SSF53067 82 192 3.11E-12 T 28-03-2018 CFK41_RS14665 2c4ed7f90d37049646a27765fb1b72a7 373 Pfam PF12802 MarR family 15 69 1.7E-6 T 28-03-2018 CFK41_RS14665 2c4ed7f90d37049646a27765fb1b72a7 373 SUPERFAMILY SSF53067 200 348 2.96E-33 T 28-03-2018 CFK41_RS14665 2c4ed7f90d37049646a27765fb1b72a7 373 Gene3D G3DSA:3.30.420.40 214 264 6.6E-20 T 28-03-2018 CFK41_RS14665 2c4ed7f90d37049646a27765fb1b72a7 373 SUPERFAMILY SSF46785 11 76 2.16E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS14665 2c4ed7f90d37049646a27765fb1b72a7 373 ProSitePatterns PS01125 ROK family signature. 207 234 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CFK41_RS14665 2c4ed7f90d37049646a27765fb1b72a7 373 Gene3D G3DSA:1.10.10.10 12 81 3.7E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS14665 2c4ed7f90d37049646a27765fb1b72a7 373 Gene3D G3DSA:3.30.420.40 83 213 1.1E-18 T 28-03-2018 CFK41_RS10685 1a13c4463aa747fb0df45d43df4a4ed8 489 Gene3D G3DSA:3.90.1300.10 10 488 5.1E-104 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CFK41_RS10685 1a13c4463aa747fb0df45d43df4a4ed8 489 SUPERFAMILY SSF75304 11 476 1.96E-103 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CFK41_RS10685 1a13c4463aa747fb0df45d43df4a4ed8 489 ProSitePatterns PS00571 Amidases signature. 165 196 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CFK41_RS10685 1a13c4463aa747fb0df45d43df4a4ed8 489 Pfam PF01425 Amidase 28 467 3.2E-75 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CFK41_RS03410 b30b3dde59b8240ec883e81119cb0632 230 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 208 224 - T 28-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CFK41_RS03410 b30b3dde59b8240ec883e81119cb0632 230 Hamap MF_00942 Endonuclease III [nth]. 1 230 31.995 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CFK41_RS03410 b30b3dde59b8240ec883e81119cb0632 230 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 48 176 1.3E-18 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CFK41_RS03410 b30b3dde59b8240ec883e81119cb0632 230 SMART SM00525 207 227 3.0E-6 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CFK41_RS03410 b30b3dde59b8240ec883e81119cb0632 230 Gene3D G3DSA:1.10.340.30 29 131 2.3E-25 T 28-03-2018 CFK41_RS03410 b30b3dde59b8240ec883e81119cb0632 230 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 208 224 8.1E-8 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CFK41_RS03410 b30b3dde59b8240ec883e81119cb0632 230 SMART SM00478 52 206 4.2E-37 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CFK41_RS03410 b30b3dde59b8240ec883e81119cb0632 230 PIRSF PIRSF001435 14 230 3.5E-36 T 28-03-2018 CFK41_RS03410 b30b3dde59b8240ec883e81119cb0632 230 SUPERFAMILY SSF48150 26 225 2.36E-58 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CFK41_RS03410 b30b3dde59b8240ec883e81119cb0632 230 Gene3D G3DSA:1.10.1670.10 132 229 5.6E-25 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CFK41_RS13905 71de397d24a3591345d85c866082fc90 246 Gene3D G3DSA:3.40.50.300 14 216 3.7E-18 T 28-03-2018 CFK41_RS13905 71de397d24a3591345d85c866082fc90 246 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 15 183 2.2E-30 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CFK41_RS13905 71de397d24a3591345d85c866082fc90 246 PIRSF PIRSF005624 3 217 3.4E-44 T 28-03-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 CFK41_RS13905 71de397d24a3591345d85c866082fc90 246 SUPERFAMILY SSF52540 7 211 1.27E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS13905 71de397d24a3591345d85c866082fc90 246 Hamap MF_01389 Urease accessory protein UreG [ureG]. 11 208 40.601 T 28-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 CFK41_RS13905 71de397d24a3591345d85c866082fc90 246 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 13 202 1.2E-71 T 28-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 CFK41_RS14345 874cb15edebbdbf34b824fd97f542495 350 SUPERFAMILY SSF52283 34 154 3.68E-13 T 28-03-2018 CFK41_RS14345 874cb15edebbdbf34b824fd97f542495 350 SUPERFAMILY SSF51735 124 311 5.37E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS14345 874cb15edebbdbf34b824fd97f542495 350 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 54 311 5.4E-6 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CFK41_RS14345 874cb15edebbdbf34b824fd97f542495 350 Gene3D G3DSA:3.40.50.720 28 136 3.5E-17 T 28-03-2018 CFK41_RS14345 874cb15edebbdbf34b824fd97f542495 350 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 134 310 9.1E-46 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CFK41_RS14345 874cb15edebbdbf34b824fd97f542495 350 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 221 243 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CFK41_RS14345 874cb15edebbdbf34b824fd97f542495 350 Gene3D G3DSA:3.40.50.720 137 310 2.8E-46 T 28-03-2018 CFK41_RS04810 b994a74d1b7047245585fea2879b5dd8 277 SUPERFAMILY SSF89082 177 268 3.92E-25 T 28-03-2018 IPR012925 TipAS antibiotic-recognition domain CFK41_RS04810 b994a74d1b7047245585fea2879b5dd8 277 Gene3D G3DSA:1.10.1660.10 14 176 2.3E-33 T 28-03-2018 CFK41_RS04810 b994a74d1b7047245585fea2879b5dd8 277 ProSitePatterns PS00552 MerR-type HTH domain signature. 19 41 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS04810 b994a74d1b7047245585fea2879b5dd8 277 Pfam PF13411 MerR HTH family regulatory protein 17 83 3.2E-12 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS04810 b994a74d1b7047245585fea2879b5dd8 277 SMART SM00422 16 85 1.9E-25 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS04810 b994a74d1b7047245585fea2879b5dd8 277 Gene3D G3DSA:1.10.490.50 178 267 7.5E-25 T 28-03-2018 CFK41_RS04810 b994a74d1b7047245585fea2879b5dd8 277 SUPERFAMILY SSF46955 16 121 4.76E-27 T 28-03-2018 IPR009061 Putative DNA-binding domain CFK41_RS04810 b994a74d1b7047245585fea2879b5dd8 277 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 28 41 9.2E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS04810 b994a74d1b7047245585fea2879b5dd8 277 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 52 72 9.2E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS04810 b994a74d1b7047245585fea2879b5dd8 277 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 17 28 9.2E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS04810 b994a74d1b7047245585fea2879b5dd8 277 Pfam PF07739 TipAS antibiotic-recognition domain 148 262 2.5E-34 T 28-03-2018 IPR012925 TipAS antibiotic-recognition domain CFK41_RS12590 5b7102e9cbd34b12c0fa880c71a517d0 499 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 11 485 2.5E-153 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CFK41_RS12590 5b7102e9cbd34b12c0fa880c71a517d0 499 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 11 467 6.9E-175 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CFK41_RS12590 5b7102e9cbd34b12c0fa880c71a517d0 499 PIRSF PIRSF000130 3 499 6.8E-195 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CFK41_RS12590 5b7102e9cbd34b12c0fa880c71a517d0 499 SMART SM01240 10 485 1.6E-288 T 28-03-2018 CFK41_RS12590 5b7102e9cbd34b12c0fa880c71a517d0 499 Pfam PF00571 CBS domain 157 207 2.3E-8 T 28-03-2018 IPR000644 CBS domain CFK41_RS12590 5b7102e9cbd34b12c0fa880c71a517d0 499 Pfam PF00571 CBS domain 98 143 1.3E-5 T 28-03-2018 IPR000644 CBS domain CFK41_RS12590 5b7102e9cbd34b12c0fa880c71a517d0 499 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 301 313 - T 28-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 CFK41_RS12590 5b7102e9cbd34b12c0fa880c71a517d0 499 SMART SM00116 162 210 1.6E-6 T 28-03-2018 IPR000644 CBS domain CFK41_RS12590 5b7102e9cbd34b12c0fa880c71a517d0 499 SMART SM00116 99 147 6.7E-5 T 28-03-2018 IPR000644 CBS domain CFK41_RS12590 5b7102e9cbd34b12c0fa880c71a517d0 499 Gene3D G3DSA:3.20.20.70 8 499 9.2E-103 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS12590 5b7102e9cbd34b12c0fa880c71a517d0 499 SUPERFAMILY SSF54631 67 207 1.39E-28 T 28-03-2018 CFK41_RS12590 5b7102e9cbd34b12c0fa880c71a517d0 499 SUPERFAMILY SSF51412 221 488 4.97E-113 T 28-03-2018 CFK41_RS12590 5b7102e9cbd34b12c0fa880c71a517d0 499 SUPERFAMILY SSF51412 10 93 4.97E-113 T 28-03-2018 CFK41_RS12590 5b7102e9cbd34b12c0fa880c71a517d0 499 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 11 498 78.699 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CFK41_RS05160 f70dc4b67023f5bb1c8ea33997b0082c 163 SMART SM00903 11 153 9.3E-29 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CFK41_RS05160 f70dc4b67023f5bb1c8ea33997b0082c 163 SUPERFAMILY SSF50475 3 153 5.89E-31 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CFK41_RS05160 f70dc4b67023f5bb1c8ea33997b0082c 163 Gene3D G3DSA:2.30.110.10 2 155 7.8E-28 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CFK41_RS05160 f70dc4b67023f5bb1c8ea33997b0082c 163 Pfam PF01613 Flavin reductase like domain 14 154 2.1E-21 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CFK41_RS05785 250e37466b08464a25b4c66d688a0f32 380 Gene3D G3DSA:3.30.360.10 189 348 3.4E-49 T 28-03-2018 CFK41_RS05785 250e37466b08464a25b4c66d688a0f32 380 SMART SM00859 32 167 1.3E-36 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CFK41_RS05785 250e37466b08464a25b4c66d688a0f32 380 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 191 351 1.0E-11 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CFK41_RS05785 250e37466b08464a25b4c66d688a0f32 380 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 32 380 3.1E-101 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CFK41_RS05785 250e37466b08464a25b4c66d688a0f32 380 SUPERFAMILY SSF55347 182 348 9.59E-42 T 28-03-2018 CFK41_RS05785 250e37466b08464a25b4c66d688a0f32 380 Gene3D G3DSA:3.40.50.720 22 188 4.1E-38 T 28-03-2018 CFK41_RS05785 250e37466b08464a25b4c66d688a0f32 380 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 177 193 - T 28-03-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CFK41_RS05785 250e37466b08464a25b4c66d688a0f32 380 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 31 374 35.563 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CFK41_RS05785 250e37466b08464a25b4c66d688a0f32 380 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 32 159 2.1E-25 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CFK41_RS05785 250e37466b08464a25b4c66d688a0f32 380 SUPERFAMILY SSF51735 30 204 1.12E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS05100 4cc5be72731d64cc3b72b90bbf6d2633 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 249 4.6E-46 T 28-03-2018 CFK41_RS05100 4cc5be72731d64cc3b72b90bbf6d2633 251 SUPERFAMILY SSF51735 7 250 6.86E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS05100 4cc5be72731d64cc3b72b90bbf6d2633 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 2.1E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS05100 4cc5be72731d64cc3b72b90bbf6d2633 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 2.1E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS05100 4cc5be72731d64cc3b72b90bbf6d2633 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.1E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS05100 4cc5be72731d64cc3b72b90bbf6d2633 251 Gene3D G3DSA:3.40.50.720 1 251 1.2E-54 T 28-03-2018 CFK41_RS05100 4cc5be72731d64cc3b72b90bbf6d2633 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 7.2E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS05100 4cc5be72731d64cc3b72b90bbf6d2633 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 7.2E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS05100 4cc5be72731d64cc3b72b90bbf6d2633 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 7.2E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS05100 4cc5be72731d64cc3b72b90bbf6d2633 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 7.2E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS05100 4cc5be72731d64cc3b72b90bbf6d2633 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 7.2E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS06970 114689c36674a002e2c05827a1a442ab 714 Pfam PF07498 Rho termination factor, N-terminal domain 9 43 7.3E-11 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CFK41_RS06970 114689c36674a002e2c05827a1a442ab 714 TIGRFAM TIGR00767 rho: transcription termination factor Rho 8 702 3.8E-185 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CFK41_RS06970 114689c36674a002e2c05827a1a442ab 714 SUPERFAMILY SSF52540 406 656 7.89E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS06970 114689c36674a002e2c05827a1a442ab 714 Hamap MF_01884 Transcription termination factor Rho [rho]. 305 704 184.922 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CFK41_RS06970 114689c36674a002e2c05827a1a442ab 714 Gene3D G3DSA:2.40.50.140 312 404 5.4E-26 T 28-03-2018 CFK41_RS06970 114689c36674a002e2c05827a1a442ab 714 SUPERFAMILY SSF50249 314 368 5.65E-10 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS06970 114689c36674a002e2c05827a1a442ab 714 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 445 648 1.3E-21 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CFK41_RS06970 114689c36674a002e2c05827a1a442ab 714 SMART SM00959 9 51 3.6E-10 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CFK41_RS06970 114689c36674a002e2c05827a1a442ab 714 SMART SM00382 455 640 3.4E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS06970 114689c36674a002e2c05827a1a442ab 714 SUPERFAMILY SSF68912 8 44 2.79E-5 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CFK41_RS06970 114689c36674a002e2c05827a1a442ab 714 Gene3D G3DSA:3.40.50.300 417 704 2.0E-53 T 28-03-2018 CFK41_RS06970 114689c36674a002e2c05827a1a442ab 714 Gene3D G3DSA:1.10.720.10 9 43 2.1E-12 T 28-03-2018 CFK41_RS06970 114689c36674a002e2c05827a1a442ab 714 Pfam PF07497 Rho termination factor, RNA-binding domain 315 412 2.0E-23 T 28-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 CFK41_RS06910 9bde3ee6b35db9efca7bd8890923a144 214 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 20 194 5.7E-16 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CFK41_RS06910 9bde3ee6b35db9efca7bd8890923a144 214 Gene3D G3DSA:3.40.50.1110 15 203 1.1E-18 T 28-03-2018 CFK41_RS06910 9bde3ee6b35db9efca7bd8890923a144 214 SUPERFAMILY SSF52266 13 202 3.3E-28 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CFK41_RS14220 6b73b60db3f61cea213f015647c0ec92 488 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 296 439 4.4E-22 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CFK41_RS14220 6b73b60db3f61cea213f015647c0ec92 488 PIRSF PIRSF000538 1 486 9.2E-86 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CFK41_RS14220 6b73b60db3f61cea213f015647c0ec92 488 SUPERFAMILY SSF53067 250 483 4.58E-33 T 28-03-2018 CFK41_RS14220 6b73b60db3f61cea213f015647c0ec92 488 Gene3D G3DSA:3.30.420.40 244 487 7.4E-38 T 28-03-2018 CFK41_RS14220 6b73b60db3f61cea213f015647c0ec92 488 SUPERFAMILY SSF53067 4 247 1.78E-41 T 28-03-2018 CFK41_RS14220 6b73b60db3f61cea213f015647c0ec92 488 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 246 2.4E-36 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CFK41_RS14220 6b73b60db3f61cea213f015647c0ec92 488 Gene3D G3DSA:3.30.420.40 1 243 1.5E-53 T 28-03-2018 CFK41_RS17340 5eb95c54a028f74ddcca4b0c8051cf27 209 SUPERFAMILY SSF51735 37 180 6.48E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS17340 5eb95c54a028f74ddcca4b0c8051cf27 209 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 102 2.7E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17340 5eb95c54a028f74ddcca4b0c8051cf27 209 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 112 131 2.7E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17340 5eb95c54a028f74ddcca4b0c8051cf27 209 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 39 50 2.7E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17340 5eb95c54a028f74ddcca4b0c8051cf27 209 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 150 2.7E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17340 5eb95c54a028f74ddcca4b0c8051cf27 209 Gene3D G3DSA:3.40.50.720 33 190 1.7E-24 T 28-03-2018 CFK41_RS17340 5eb95c54a028f74ddcca4b0c8051cf27 209 Pfam PF00106 short chain dehydrogenase 38 151 1.1E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17340 5eb95c54a028f74ddcca4b0c8051cf27 209 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 39 50 1.8E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17340 5eb95c54a028f74ddcca4b0c8051cf27 209 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 100 1.8E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17340 5eb95c54a028f74ddcca4b0c8051cf27 209 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 112 131 1.8E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS07735 da2cf3e6a563ae118cfdc6b6c971ad65 216 SUPERFAMILY SSF46894 141 215 1.09E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CFK41_RS07735 da2cf3e6a563ae118cfdc6b6c971ad65 216 SMART SM00448 2 117 1.0E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS07735 da2cf3e6a563ae118cfdc6b6c971ad65 216 Gene3D G3DSA:1.10.10.10 136 215 4.3E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS07735 da2cf3e6a563ae118cfdc6b6c971ad65 216 SUPERFAMILY SSF52172 1 134 2.56E-35 T 28-03-2018 IPR011006 CheY-like superfamily CFK41_RS07735 da2cf3e6a563ae118cfdc6b6c971ad65 216 SMART SM00421 153 210 9.5E-25 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS07735 da2cf3e6a563ae118cfdc6b6c971ad65 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 1.7E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS07735 da2cf3e6a563ae118cfdc6b6c971ad65 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 1.7E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS07735 da2cf3e6a563ae118cfdc6b6c971ad65 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 1.7E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS07735 da2cf3e6a563ae118cfdc6b6c971ad65 216 Gene3D G3DSA:3.40.50.2300 1 135 2.1E-40 T 28-03-2018 CFK41_RS07735 da2cf3e6a563ae118cfdc6b6c971ad65 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 210 1.6E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS07735 da2cf3e6a563ae118cfdc6b6c971ad65 216 Pfam PF00072 Response regulator receiver domain 4 118 6.4E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS02120 5dd8666dba330093052250b3203b0c58 354 SUPERFAMILY SSF103481 40 134 4.32E-10 T 28-03-2018 CFK41_RS02120 5dd8666dba330093052250b3203b0c58 354 SUPERFAMILY SSF103481 211 289 1.31E-10 T 28-03-2018 CFK41_RS02120 5dd8666dba330093052250b3203b0c58 354 Pfam PF00892 EamA-like transporter family 142 282 2.5E-12 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CFK41_RS02120 5dd8666dba330093052250b3203b0c58 354 Pfam PF00892 EamA-like transporter family 7 130 6.2E-11 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CFK41_RS11520 a2e006acde8f2eb205cb7c9c293e08f5 607 Pfam PF03717 Penicillin-binding Protein dimerisation domain 86 243 1.2E-12 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CFK41_RS11520 a2e006acde8f2eb205cb7c9c293e08f5 607 SUPERFAMILY SSF56601 214 599 4.64E-89 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CFK41_RS11520 a2e006acde8f2eb205cb7c9c293e08f5 607 Gene3D G3DSA:3.90.1310.10 55 257 1.1E-39 T 28-03-2018 CFK41_RS11520 a2e006acde8f2eb205cb7c9c293e08f5 607 Pfam PF00905 Penicillin binding protein transpeptidase domain 286 581 4.1E-72 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CFK41_RS11520 a2e006acde8f2eb205cb7c9c293e08f5 607 Gene3D G3DSA:3.40.710.10 258 593 4.2E-91 T 28-03-2018 CFK41_RS11520 a2e006acde8f2eb205cb7c9c293e08f5 607 SUPERFAMILY SSF56519 83 260 1.1E-35 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CFK41_RS16970 5b608e93280c1ad0a6f5d39fc4cc23c9 348 SUPERFAMILY SSF161098 104 308 9.68E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS16970 5b608e93280c1ad0a6f5d39fc4cc23c9 348 Gene3D G3DSA:1.10.3720.10 2 314 3.1E-34 T 28-03-2018 CFK41_RS16970 5b608e93280c1ad0a6f5d39fc4cc23c9 348 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 127 324 1.8E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS11450 bcb45dcce6e009009bf5e75c1ada0679 177 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 86 101 8.4E-14 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CFK41_RS11450 bcb45dcce6e009009bf5e75c1ada0679 177 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 43 51 8.4E-14 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CFK41_RS11450 bcb45dcce6e009009bf5e75c1ada0679 177 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 124 140 8.4E-14 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CFK41_RS11450 bcb45dcce6e009009bf5e75c1ada0679 177 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 2 149 13.799 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CFK41_RS11450 bcb45dcce6e009009bf5e75c1ada0679 177 TIGRFAM TIGR00077 lspA: signal peptidase II 3 144 1.3E-25 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CFK41_RS11450 bcb45dcce6e009009bf5e75c1ada0679 177 Pfam PF01252 Signal peptidase (SPase) II 4 142 2.3E-32 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CFK41_RS09850 7eb0d37ad37e855732847fd42b5c46db 266 Gene3D G3DSA:1.10.760.10 28 137 5.7E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CFK41_RS09850 7eb0d37ad37e855732847fd42b5c46db 266 SUPERFAMILY SSF46626 14 133 7.76E-20 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CFK41_RS09850 7eb0d37ad37e855732847fd42b5c46db 266 PIRSF PIRSF000007 1 265 4.5E-102 T 28-03-2018 IPR009152 Cytochrome bc1 complex, cytochrome c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 CFK41_RS09850 7eb0d37ad37e855732847fd42b5c46db 266 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 147 220 1.6E-11 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CFK41_RS09850 7eb0d37ad37e855732847fd42b5c46db 266 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 46 126 1.8E-7 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CFK41_RS09850 7eb0d37ad37e855732847fd42b5c46db 266 SUPERFAMILY SSF46626 128 222 1.36E-27 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CFK41_RS09850 7eb0d37ad37e855732847fd42b5c46db 266 Gene3D G3DSA:1.10.760.10 138 233 4.4E-16 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CFK41_RS10510 73dfcb3e17cb6e7ca2479be621b2d3f4 184 SUPERFAMILY SSF53271 4 182 9.7E-61 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CFK41_RS10510 73dfcb3e17cb6e7ca2479be621b2d3f4 184 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 13 177 3.8E-65 T 28-03-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 CFK41_RS10510 73dfcb3e17cb6e7ca2479be621b2d3f4 184 Pfam PF00156 Phosphoribosyl transferase domain 14 164 3.0E-29 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CFK41_RS10510 73dfcb3e17cb6e7ca2479be621b2d3f4 184 Gene3D G3DSA:3.40.50.2020 1 184 6.5E-49 T 28-03-2018 CFK41_RS07380 8b833b81d2335cec258182ff9d712cb9 332 SUPERFAMILY SSF51735 6 181 1.01E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS07380 8b833b81d2335cec258182ff9d712cb9 332 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 5 323 35.105 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CFK41_RS07380 8b833b81d2335cec258182ff9d712cb9 332 Gene3D G3DSA:3.40.50.720 2 180 3.8E-38 T 28-03-2018 CFK41_RS07380 8b833b81d2335cec258182ff9d712cb9 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 59 86 7.9E-43 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CFK41_RS07380 8b833b81d2335cec258182ff9d712cb9 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 174 198 7.9E-43 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CFK41_RS07380 8b833b81d2335cec258182ff9d712cb9 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 9 26 7.9E-43 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CFK41_RS07380 8b833b81d2335cec258182ff9d712cb9 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 134 154 7.9E-43 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CFK41_RS07380 8b833b81d2335cec258182ff9d712cb9 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 239 256 7.9E-43 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CFK41_RS07380 8b833b81d2335cec258182ff9d712cb9 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 199 223 7.9E-43 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CFK41_RS07380 8b833b81d2335cec258182ff9d712cb9 332 PIRSF PIRSF000114 2 332 2.2E-88 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CFK41_RS07380 8b833b81d2335cec258182ff9d712cb9 332 Gene3D G3DSA:1.10.1040.10 181 331 4.2E-48 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CFK41_RS07380 8b833b81d2335cec258182ff9d712cb9 332 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 8 160 2.1E-43 T 28-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CFK41_RS07380 8b833b81d2335cec258182ff9d712cb9 332 SUPERFAMILY SSF48179 180 332 8.33E-51 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CFK41_RS07380 8b833b81d2335cec258182ff9d712cb9 332 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 181 320 9.9E-46 T 28-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CFK41_RS10225 79d2d5f624f2bde720e0b637622037c0 502 SUPERFAMILY SSF51161 230 446 2.71E-42 T 28-03-2018 IPR011004 Trimeric LpxA-like CFK41_RS10225 79d2d5f624f2bde720e0b637622037c0 502 SUPERFAMILY SSF53448 11 263 7.38E-62 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS10225 79d2d5f624f2bde720e0b637622037c0 502 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 9 462 39.45 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CFK41_RS10225 79d2d5f624f2bde720e0b637622037c0 502 Pfam PF12804 MobA-like NTP transferase domain 12 148 6.1E-25 T 28-03-2018 IPR025877 MobA-like NTP transferase CFK41_RS10225 79d2d5f624f2bde720e0b637622037c0 502 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 405 439 1.4E-4 T 28-03-2018 IPR001451 Hexapeptide repeat CFK41_RS10225 79d2d5f624f2bde720e0b637622037c0 502 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 276 310 2.0E-4 T 28-03-2018 IPR001451 Hexapeptide repeat CFK41_RS10225 79d2d5f624f2bde720e0b637622037c0 502 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 362 395 2.2E-4 T 28-03-2018 IPR001451 Hexapeptide repeat CFK41_RS10225 79d2d5f624f2bde720e0b637622037c0 502 Gene3D G3DSA:3.90.550.10 4 262 4.2E-59 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS10225 79d2d5f624f2bde720e0b637622037c0 502 Gene3D G3DSA:2.160.10.10 263 448 5.8E-41 T 28-03-2018 CFK41_RS10225 79d2d5f624f2bde720e0b637622037c0 502 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 11 463 2.4E-167 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CFK41_RS08625 e8906a3093975ecc2d41e7fb4eb6f6d9 414 Hamap MF_01697 L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [mshC]. 9 412 49.978 T 28-03-2018 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 CFK41_RS08625 e8906a3093975ecc2d41e7fb4eb6f6d9 414 Gene3D G3DSA:1.20.120.640 333 412 9.7E-11 T 28-03-2018 CFK41_RS08625 e8906a3093975ecc2d41e7fb4eb6f6d9 414 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 249 270 8.6E-17 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CFK41_RS08625 e8906a3093975ecc2d41e7fb4eb6f6d9 414 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 42 53 8.6E-17 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CFK41_RS08625 e8906a3093975ecc2d41e7fb4eb6f6d9 414 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 78 87 8.6E-17 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CFK41_RS08625 e8906a3093975ecc2d41e7fb4eb6f6d9 414 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 218 236 8.6E-17 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CFK41_RS08625 e8906a3093975ecc2d41e7fb4eb6f6d9 414 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 33 340 1.9E-77 T 28-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 CFK41_RS08625 e8906a3093975ecc2d41e7fb4eb6f6d9 414 TIGRFAM TIGR03447 mycothiol_MshC: cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 2 412 3.9E-164 T 28-03-2018 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 CFK41_RS08625 e8906a3093975ecc2d41e7fb4eb6f6d9 414 SUPERFAMILY SSF52374 20 336 2.57E-64 T 28-03-2018 CFK41_RS08625 e8906a3093975ecc2d41e7fb4eb6f6d9 414 Gene3D G3DSA:3.40.50.620 1 332 8.5E-66 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS04620 b2cfb7c2d18c1ef29bcfa8cc17822bc7 111 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 33 104 1.0E-32 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS04620 b2cfb7c2d18c1ef29bcfa8cc17822bc7 111 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 33 104 7.0E-26 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS04620 b2cfb7c2d18c1ef29bcfa8cc17822bc7 111 SUPERFAMILY SSF50249 33 110 5.57E-29 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS04620 b2cfb7c2d18c1ef29bcfa8cc17822bc7 111 Gene3D G3DSA:2.40.50.140 33 110 7.8E-28 T 28-03-2018 CFK41_RS04620 b2cfb7c2d18c1ef29bcfa8cc17822bc7 111 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 33 108 24.007 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS04620 b2cfb7c2d18c1ef29bcfa8cc17822bc7 111 PRINTS PR00973 Ribosomal protein S17 family signature 84 94 3.3E-10 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS04620 b2cfb7c2d18c1ef29bcfa8cc17822bc7 111 PRINTS PR00973 Ribosomal protein S17 family signature 52 75 3.3E-10 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS04620 b2cfb7c2d18c1ef29bcfa8cc17822bc7 111 PRINTS PR00973 Ribosomal protein S17 family signature 94 101 3.3E-10 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS04620 b2cfb7c2d18c1ef29bcfa8cc17822bc7 111 Pfam PF00366 Ribosomal protein S17 38 105 3.0E-29 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS14760 3b7081218853a37e975c80f9b06eb6ce 493 Gene3D G3DSA:3.40.50.1820 3 451 6.7E-69 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS14760 3b7081218853a37e975c80f9b06eb6ce 493 SUPERFAMILY SSF53474 16 427 3.94E-66 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS14760 3b7081218853a37e975c80f9b06eb6ce 493 Pfam PF00135 Carboxylesterase family 18 402 1.5E-52 T 28-03-2018 IPR002018 Carboxylesterase, type B CFK41_RS02660 43d78a8046e9bfe9a47fc63d5c8fbf7f 74 Gene3D G3DSA:3.30.565.10 1 74 2.9E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS02660 43d78a8046e9bfe9a47fc63d5c8fbf7f 74 SUPERFAMILY SSF55874 4 73 6.43E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS17165 150887560908734eba4cc4ba561b3530 253 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 247 30.357 T 28-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS17165 150887560908734eba4cc4ba561b3530 253 SUPERFAMILY SSF51351 3 246 7.85E-66 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS17165 150887560908734eba4cc4ba561b3530 253 Pfam PF00121 Triosephosphate isomerase 5 243 2.6E-60 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS17165 150887560908734eba4cc4ba561b3530 253 Gene3D G3DSA:3.20.20.70 1 253 4.2E-71 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS15865 823df551c16b6e3cd5a8fe15e3b06e8d 481 SUPERFAMILY SSF103473 453 478 6.15E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS15865 823df551c16b6e3cd5a8fe15e3b06e8d 481 SUPERFAMILY SSF103473 4 183 6.15E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS15865 823df551c16b6e3cd5a8fe15e3b06e8d 481 SUPERFAMILY SSF103473 230 401 6.15E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS15865 823df551c16b6e3cd5a8fe15e3b06e8d 481 Pfam PF07690 Major Facilitator Superfamily 5 391 8.2E-46 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS15865 823df551c16b6e3cd5a8fe15e3b06e8d 481 Gene3D G3DSA:1.20.1250.20 241 480 4.4E-22 T 28-03-2018 CFK41_RS15865 823df551c16b6e3cd5a8fe15e3b06e8d 481 Gene3D G3DSA:1.20.1250.20 1 183 4.4E-28 T 28-03-2018 CFK41_RS05970 2034bc6e870df90ce021d8aae3db1c12 422 Gene3D G3DSA:3.40.640.10 37 273 3.9E-49 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS05970 2034bc6e870df90ce021d8aae3db1c12 422 PIRSF PIRSF000412 2 420 1.8E-149 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CFK41_RS05970 2034bc6e870df90ce021d8aae3db1c12 422 SUPERFAMILY SSF53383 5 417 2.74E-162 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS05970 2034bc6e870df90ce021d8aae3db1c12 422 Pfam PF00464 Serine hydroxymethyltransferase 9 389 1.5E-157 T 28-03-2018 CFK41_RS05970 2034bc6e870df90ce021d8aae3db1c12 422 Gene3D G3DSA:3.90.1150.10 274 415 1.2E-49 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS05970 2034bc6e870df90ce021d8aae3db1c12 422 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 417 48.868 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CFK41_RS13335 ebac735b2e99056bb8b295ebf8afd737 573 Gene3D G3DSA:3.40.50.720 123 246 5.8E-11 T 28-03-2018 CFK41_RS13335 ebac735b2e99056bb8b295ebf8afd737 573 Gene3D G3DSA:3.40.50.720 349 474 1.1E-19 T 28-03-2018 CFK41_RS13335 ebac735b2e99056bb8b295ebf8afd737 573 Gene3D G3DSA:3.30.70.1450 493 569 0.0051 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CFK41_RS13335 ebac735b2e99056bb8b295ebf8afd737 573 SUPERFAMILY SSF81324 20 143 1.2E-18 T 28-03-2018 CFK41_RS13335 ebac735b2e99056bb8b295ebf8afd737 573 Pfam PF02254 TrkA-N domain 355 474 1.6E-21 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CFK41_RS13335 ebac735b2e99056bb8b295ebf8afd737 573 Pfam PF02254 TrkA-N domain 133 245 8.8E-9 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CFK41_RS13335 ebac735b2e99056bb8b295ebf8afd737 573 SUPERFAMILY SSF51735 354 488 2.66E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS13335 ebac735b2e99056bb8b295ebf8afd737 573 SUPERFAMILY SSF116726 276 345 1.14E-6 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CFK41_RS13335 ebac735b2e99056bb8b295ebf8afd737 573 Gene3D G3DSA:1.10.287.70 8 117 6.6E-17 T 28-03-2018 CFK41_RS13335 ebac735b2e99056bb8b295ebf8afd737 573 Gene3D G3DSA:3.30.70.1450 271 348 9.1E-9 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CFK41_RS13335 ebac735b2e99056bb8b295ebf8afd737 573 Pfam PF07885 Ion channel 32 104 3.9E-13 T 28-03-2018 IPR013099 Potassium channel domain CFK41_RS13335 ebac735b2e99056bb8b295ebf8afd737 573 SUPERFAMILY SSF51735 131 260 1.38E-12 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS02430 7d93954f44ae69f3372acb6450b029c6 367 Pfam PF00005 ABC transporter 70 200 9.8E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS02430 7d93954f44ae69f3372acb6450b029c6 367 SMART SM00382 78 249 7.1E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS02430 7d93954f44ae69f3372acb6450b029c6 367 Gene3D G3DSA:3.40.50.300 30 320 1.0E-43 T 28-03-2018 CFK41_RS02430 7d93954f44ae69f3372acb6450b029c6 367 ProSitePatterns PS00211 ABC transporters family signature. 173 187 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS02430 7d93954f44ae69f3372acb6450b029c6 367 SUPERFAMILY SSF52540 67 263 5.1E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS13680 9e5d0ac9132cb62ff2336ed38363a1d8 553 SUPERFAMILY SSF51905 488 552 6.55E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS13680 9e5d0ac9132cb62ff2336ed38363a1d8 553 SUPERFAMILY SSF51905 6 280 6.55E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS13680 9e5d0ac9132cb62ff2336ed38363a1d8 553 PIRSF PIRSF036654 2 552 2.9E-267 T 28-03-2018 IPR014614 Uncharacterised conserved protein UCP036654 GO:0016627|GO:0055114 CFK41_RS13680 9e5d0ac9132cb62ff2336ed38363a1d8 553 Pfam PF00890 FAD binding domain 8 534 6.0E-100 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CFK41_RS13680 9e5d0ac9132cb62ff2336ed38363a1d8 553 Gene3D G3DSA:3.50.50.60 2 551 8.8E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS13350 33d1efc61c0b2b527a1bb42992227f3e 344 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 132 5.8E-23 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CFK41_RS13350 33d1efc61c0b2b527a1bb42992227f3e 344 SUPERFAMILY SSF50129 1 173 2.28E-40 T 28-03-2018 IPR011032 GroES-like CFK41_RS13350 33d1efc61c0b2b527a1bb42992227f3e 344 Gene3D G3DSA:3.40.50.720 162 285 3.3E-26 T 28-03-2018 CFK41_RS13350 33d1efc61c0b2b527a1bb42992227f3e 344 SUPERFAMILY SSF51735 138 304 3.47E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS13350 33d1efc61c0b2b527a1bb42992227f3e 344 SMART SM00829 7 338 0.0052 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CFK41_RS13350 33d1efc61c0b2b527a1bb42992227f3e 344 Pfam PF00107 Zinc-binding dehydrogenase 174 300 5.0E-24 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CFK41_RS13350 33d1efc61c0b2b527a1bb42992227f3e 344 Gene3D G3DSA:3.90.180.10 1 161 1.2E-41 T 28-03-2018 CFK41_RS06130 b2de22dcc5f4615d1b3aed337f53ae73 231 SMART SM00862 149 225 2.3E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CFK41_RS06130 b2de22dcc5f4615d1b3aed337f53ae73 231 Pfam PF00072 Response regulator receiver domain 5 115 1.0E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS06130 b2de22dcc5f4615d1b3aed337f53ae73 231 Gene3D G3DSA:1.10.10.10 124 231 4.7E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS06130 b2de22dcc5f4615d1b3aed337f53ae73 231 Gene3D G3DSA:3.40.50.2300 1 123 2.0E-36 T 28-03-2018 CFK41_RS06130 b2de22dcc5f4615d1b3aed337f53ae73 231 SMART SM00448 2 114 1.5E-39 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS06130 b2de22dcc5f4615d1b3aed337f53ae73 231 SUPERFAMILY SSF52172 3 182 7.47E-39 T 28-03-2018 IPR011006 CheY-like superfamily CFK41_RS06130 b2de22dcc5f4615d1b3aed337f53ae73 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 225 3.3E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CFK41_RS00785 34a3a871cafcc43fd1ce4f98084952a2 333 SUPERFAMILY SSF81345 24 329 1.83E-64 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CFK41_RS00785 34a3a871cafcc43fd1ce4f98084952a2 333 Pfam PF01032 FecCD transport family 30 328 8.2E-63 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CFK41_RS00785 34a3a871cafcc43fd1ce4f98084952a2 333 Gene3D G3DSA:1.10.3470.10 11 331 5.7E-39 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CFK41_RS00430 fdd230e3fce3b9aee3fc5d28b5fbc35c 478 Pfam PF02614 Glucuronate isomerase 22 449 1.5E-74 T 28-03-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 CFK41_RS00430 fdd230e3fce3b9aee3fc5d28b5fbc35c 478 Gene3D G3DSA:3.20.20.140 103 471 7.9E-116 T 28-03-2018 CFK41_RS00430 fdd230e3fce3b9aee3fc5d28b5fbc35c 478 Gene3D G3DSA:3.20.20.140 6 94 5.5E-21 T 28-03-2018 CFK41_RS00430 fdd230e3fce3b9aee3fc5d28b5fbc35c 478 SUPERFAMILY SSF51556 8 469 1.5E-138 T 28-03-2018 IPR032466 Metal-dependent hydrolase CFK41_RS17090 0e1845ffced542c487a6c1fb74da2966 330 SUPERFAMILY SSF52283 24 143 2.08E-21 T 28-03-2018 CFK41_RS17090 0e1845ffced542c487a6c1fb74da2966 330 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 233 249 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CFK41_RS17090 0e1845ffced542c487a6c1fb74da2966 330 Gene3D G3DSA:3.40.50.720 121 293 7.1E-50 T 28-03-2018 CFK41_RS17090 0e1845ffced542c487a6c1fb74da2966 330 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 32 325 4.0E-19 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CFK41_RS17090 0e1845ffced542c487a6c1fb74da2966 330 SUPERFAMILY SSF51735 111 292 5.07E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS17090 0e1845ffced542c487a6c1fb74da2966 330 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 119 292 8.6E-53 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CFK41_RS17090 0e1845ffced542c487a6c1fb74da2966 330 Gene3D G3DSA:3.40.50.720 1 120 7.3E-20 T 28-03-2018 CFK41_RS14915 35dd1fe7522d110bc3083ddf0d72434d 288 Gene3D G3DSA:1.10.600.10 12 288 3.0E-49 T 28-03-2018 IPR008949 Isoprenoid synthase domain CFK41_RS14915 35dd1fe7522d110bc3083ddf0d72434d 288 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 174 200 - T 28-03-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CFK41_RS14915 35dd1fe7522d110bc3083ddf0d72434d 288 SUPERFAMILY SSF48576 26 286 2.48E-55 T 28-03-2018 IPR008949 Isoprenoid synthase domain CFK41_RS14915 35dd1fe7522d110bc3083ddf0d72434d 288 Pfam PF00494 Squalene/phytoene synthase 28 271 5.2E-35 T 28-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 CFK41_RS01285 736dcda3e4bccaea9d570fccc1d1612e 436 Gene3D G3DSA:3.40.190.10 31 211 4.1E-29 T 28-03-2018 CFK41_RS01285 736dcda3e4bccaea9d570fccc1d1612e 436 SUPERFAMILY SSF53850 21 429 4.03E-43 T 28-03-2018 CFK41_RS01285 736dcda3e4bccaea9d570fccc1d1612e 436 Pfam PF13416 Bacterial extracellular solute-binding protein 58 363 2.6E-23 T 28-03-2018 CFK41_RS01285 736dcda3e4bccaea9d570fccc1d1612e 436 Gene3D G3DSA:3.40.190.10 235 380 1.6E-4 T 28-03-2018 CFK41_RS11830 53d2fb6aaef3a316bbd1fa9d1d658d71 188 Hamap MF_00040 Ribosome-recycling factor [frr]. 6 188 25.003 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CFK41_RS11830 53d2fb6aaef3a316bbd1fa9d1d658d71 188 Pfam PF01765 Ribosome recycling factor 24 185 3.0E-55 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CFK41_RS11830 53d2fb6aaef3a316bbd1fa9d1d658d71 188 Gene3D G3DSA:1.10.132.20 6 76 1.1E-9 T 28-03-2018 CFK41_RS11830 53d2fb6aaef3a316bbd1fa9d1d658d71 188 Gene3D G3DSA:1.10.132.20 77 187 1.8E-32 T 28-03-2018 CFK41_RS11830 53d2fb6aaef3a316bbd1fa9d1d658d71 188 TIGRFAM TIGR00496 frr: ribosome recycling factor 14 187 3.4E-59 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CFK41_RS11830 53d2fb6aaef3a316bbd1fa9d1d658d71 188 SUPERFAMILY SSF55194 7 185 3.14E-63 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CFK41_RS17310 aac50d5f702717cd2179a6418ca52439 109 Gene3D G3DSA:3.30.70.20 3 44 7.3E-11 T 28-03-2018 CFK41_RS17310 aac50d5f702717cd2179a6418ca52439 109 Pfam PF00037 4Fe-4S binding domain 34 55 3.5E-8 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CFK41_RS17310 aac50d5f702717cd2179a6418ca52439 109 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CFK41_RS17310 aac50d5f702717cd2179a6418ca52439 109 SUPERFAMILY SSF54862 3 95 5.68E-20 T 28-03-2018 CFK41_RS17310 aac50d5f702717cd2179a6418ca52439 109 PRINTS PR00354 7Fe ferredoxin signature 19 29 1.7E-16 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CFK41_RS17310 aac50d5f702717cd2179a6418ca52439 109 PRINTS PR00354 7Fe ferredoxin signature 9 19 1.7E-16 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CFK41_RS17310 aac50d5f702717cd2179a6418ca52439 109 PRINTS PR00354 7Fe ferredoxin signature 35 52 1.7E-16 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CFK41_RS17310 aac50d5f702717cd2179a6418ca52439 109 Gene3D G3DSA:3.30.70.20 45 95 1.8E-8 T 28-03-2018 CFK41_RS15245 45925aeb942c3392e92539719585a7fe 318 SUPERFAMILY SSF100950 66 315 8.37E-53 T 28-03-2018 CFK41_RS15245 45925aeb942c3392e92539719585a7fe 318 Gene3D G3DSA:3.40.50.1360 53 316 4.5E-35 T 28-03-2018 CFK41_RS15245 45925aeb942c3392e92539719585a7fe 318 Pfam PF04198 Putative sugar-binding domain 65 315 1.1E-52 T 28-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 CFK41_RS15245 45925aeb942c3392e92539719585a7fe 318 Gene3D G3DSA:1.10.10.60 1 52 3.0E-14 T 28-03-2018 CFK41_RS15245 45925aeb942c3392e92539719585a7fe 318 SUPERFAMILY SSF46689 14 73 2.87E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS15245 45925aeb942c3392e92539719585a7fe 318 Pfam PF04545 Sigma-70, region 4 15 47 6.1E-6 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS03060 40fb80593c26947c5249054ce23acc56 280 Gene3D G3DSA:1.10.101.10 76 155 3.0E-20 T 28-03-2018 IPR002477 Peptidoglycan binding-like CFK41_RS03060 40fb80593c26947c5249054ce23acc56 280 Gene3D G3DSA:3.90.1720.10 162 275 3.1E-34 T 28-03-2018 CFK41_RS03060 40fb80593c26947c5249054ce23acc56 280 SUPERFAMILY SSF54001 163 270 1.73E-36 T 28-03-2018 CFK41_RS03060 40fb80593c26947c5249054ce23acc56 280 Pfam PF01471 Putative peptidoglycan binding domain 90 145 6.7E-14 T 28-03-2018 IPR002477 Peptidoglycan binding-like CFK41_RS03060 40fb80593c26947c5249054ce23acc56 280 Pfam PF00877 NlpC/P60 family 184 265 1.3E-21 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CFK41_RS03060 40fb80593c26947c5249054ce23acc56 280 SUPERFAMILY SSF47090 81 146 3.66E-16 T 28-03-2018 IPR002477 Peptidoglycan binding-like CFK41_RS15060 52eef5ce721bb2219a3064bb6a13f45f 104 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 80 7.8E-18 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS15060 52eef5ce721bb2219a3064bb6a13f45f 104 SUPERFAMILY SSF143800 1 80 1.73E-20 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS15060 52eef5ce721bb2219a3064bb6a13f45f 104 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 25.786 T 28-03-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS15060 52eef5ce721bb2219a3064bb6a13f45f 104 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS15060 52eef5ce721bb2219a3064bb6a13f45f 104 PRINTS PR01249 Ribosomal protein L31 signature 2 19 2.4E-17 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS15060 52eef5ce721bb2219a3064bb6a13f45f 104 PRINTS PR01249 Ribosomal protein L31 signature 45 60 2.4E-17 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS15060 52eef5ce721bb2219a3064bb6a13f45f 104 PRINTS PR01249 Ribosomal protein L31 signature 60 78 2.4E-17 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS15060 52eef5ce721bb2219a3064bb6a13f45f 104 Pfam PF01197 Ribosomal protein L31 1 79 4.2E-28 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS13330 53d703a35dc6b105629d92c83aaacf30 158 Pfam PF00578 AhpC/TSA family 10 138 1.1E-31 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CFK41_RS13330 53d703a35dc6b105629d92c83aaacf30 158 SUPERFAMILY SSF52833 8 152 1.23E-38 T 28-03-2018 IPR012336 Thioredoxin-like fold CFK41_RS13330 53d703a35dc6b105629d92c83aaacf30 158 Gene3D G3DSA:3.40.30.10 2 156 6.8E-33 T 28-03-2018 CFK41_RS11115 6aa6d9a9b7146a27eae0c7faa43ba9f6 604 Gene3D G3DSA:3.30.565.10 477 601 2.7E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS11115 6aa6d9a9b7146a27eae0c7faa43ba9f6 604 SUPERFAMILY SSF55874 489 597 2.06E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS11115 6aa6d9a9b7146a27eae0c7faa43ba9f6 604 SMART SM00387 507 600 4.8E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS11115 6aa6d9a9b7146a27eae0c7faa43ba9f6 604 Pfam PF07730 Histidine kinase 402 468 3.8E-17 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CFK41_RS11115 6aa6d9a9b7146a27eae0c7faa43ba9f6 604 Pfam PF13796 Putative sensor 21 189 2.2E-13 T 28-03-2018 IPR025828 Putative sensor domain CFK41_RS06105 552d08085f0251b8c09ecaa24017595b 566 Pfam PF05960 Bacterial protein of unknown function (DUF885) 36 565 4.3E-149 T 28-03-2018 IPR010281 Protein of unknown function DUF885 CFK41_RS16535 be5e4169b75c1bfeca073cc3a8f3b69d 501 Gene3D G3DSA:1.10.1040.10 284 496 2.9E-39 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CFK41_RS16535 be5e4169b75c1bfeca073cc3a8f3b69d 501 SUPERFAMILY SSF48179 286 490 1.26E-35 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CFK41_RS16535 be5e4169b75c1bfeca073cc3a8f3b69d 501 SUPERFAMILY SSF51735 22 282 2.72E-75 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS16535 be5e4169b75c1bfeca073cc3a8f3b69d 501 PRINTS PR00084 Mannitol dehydrogenase signature 29 39 4.2E-17 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CFK41_RS16535 be5e4169b75c1bfeca073cc3a8f3b69d 501 PRINTS PR00084 Mannitol dehydrogenase signature 179 192 4.2E-17 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CFK41_RS16535 be5e4169b75c1bfeca073cc3a8f3b69d 501 PRINTS PR00084 Mannitol dehydrogenase signature 250 265 4.2E-17 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CFK41_RS16535 be5e4169b75c1bfeca073cc3a8f3b69d 501 PRINTS PR00084 Mannitol dehydrogenase signature 220 233 4.2E-17 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CFK41_RS16535 be5e4169b75c1bfeca073cc3a8f3b69d 501 Gene3D G3DSA:3.40.50.720 16 283 1.6E-86 T 28-03-2018 CFK41_RS16535 be5e4169b75c1bfeca073cc3a8f3b69d 501 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 28 188 9.7E-28 T 28-03-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 CFK41_RS16535 be5e4169b75c1bfeca073cc3a8f3b69d 501 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 220 447 5.6E-55 T 28-03-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 CFK41_RS16535 be5e4169b75c1bfeca073cc3a8f3b69d 501 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 220 232 - T 28-03-2018 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CFK41_RS17150 23d5324e818fa22912fc8d1eeee1e77b 571 SUPERFAMILY SSF101473 370 567 1.09E-40 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CFK41_RS17150 23d5324e818fa22912fc8d1eeee1e77b 571 Gene3D G3DSA:3.30.1180.20 183 335 1.1E-40 T 28-03-2018 CFK41_RS17150 23d5324e818fa22912fc8d1eeee1e77b 571 Gene3D G3DSA:3.40.50.10440 12 182 2.9E-51 T 28-03-2018 CFK41_RS17150 23d5324e818fa22912fc8d1eeee1e77b 571 Pfam PF02734 DAK2 domain 394 566 1.1E-40 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CFK41_RS17150 23d5324e818fa22912fc8d1eeee1e77b 571 SMART SM01120 393 568 1.1E-47 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CFK41_RS17150 23d5324e818fa22912fc8d1eeee1e77b 571 SUPERFAMILY SSF82549 11 332 3.14E-97 T 28-03-2018 CFK41_RS17150 23d5324e818fa22912fc8d1eeee1e77b 571 Pfam PF02733 Dak1 domain 18 330 1.1E-102 T 28-03-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CFK41_RS06670 15981f658dff4a22251a4b48354e3147 147 Gene3D G3DSA:3.40.630.30 15 147 4.4E-16 T 28-03-2018 CFK41_RS06670 15981f658dff4a22251a4b48354e3147 147 Pfam PF13673 Acetyltransferase (GNAT) domain 51 139 5.5E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS06670 15981f658dff4a22251a4b48354e3147 147 SUPERFAMILY SSF55729 25 138 1.26E-16 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS06255 6ca5feb944f5f73c3814ad68f1610153 364 Gene3D G3DSA:3.30.1330.100 125 230 1.3E-22 T 28-03-2018 CFK41_RS06255 6ca5feb944f5f73c3814ad68f1610153 364 Gene3D G3DSA:3.30.1330.100 15 123 4.9E-19 T 28-03-2018 CFK41_RS06255 6ca5feb944f5f73c3814ad68f1610153 364 SUPERFAMILY SSF144010 21 250 8.89E-52 T 28-03-2018 CFK41_RS06255 6ca5feb944f5f73c3814ad68f1610153 364 Pfam PF01996 F420-0:Gamma-glutamyl ligase 95 223 8.4E-29 T 28-03-2018 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 CFK41_RS06055 0d4f30073d49944d0350dd2dd13ca5ee 336 Gene3D G3DSA:3.90.180.10 2 169 1.4E-39 T 28-03-2018 CFK41_RS06055 0d4f30073d49944d0350dd2dd13ca5ee 336 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CFK41_RS06055 0d4f30073d49944d0350dd2dd13ca5ee 336 Pfam PF00107 Zinc-binding dehydrogenase 179 297 4.0E-12 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CFK41_RS06055 0d4f30073d49944d0350dd2dd13ca5ee 336 SUPERFAMILY SSF50129 2 178 7.15E-43 T 28-03-2018 IPR011032 GroES-like CFK41_RS06055 0d4f30073d49944d0350dd2dd13ca5ee 336 SUPERFAMILY SSF51735 146 300 1.36E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS06055 0d4f30073d49944d0350dd2dd13ca5ee 336 Gene3D G3DSA:3.40.50.720 170 282 2.1E-14 T 28-03-2018 CFK41_RS06055 0d4f30073d49944d0350dd2dd13ca5ee 336 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 139 2.4E-21 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CFK41_RS09495 61007459b2c020a0433047e0f65a1974 426 SUPERFAMILY SSF102645 195 422 1.03E-53 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CFK41_RS09495 61007459b2c020a0433047e0f65a1974 426 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 8 418 4.4E-101 T 28-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 CFK41_RS09495 61007459b2c020a0433047e0f65a1974 426 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 197 392 8.8E-56 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CFK41_RS09495 61007459b2c020a0433047e0f65a1974 426 SUPERFAMILY SSF52507 6 180 2.22E-51 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CFK41_RS09495 61007459b2c020a0433047e0f65a1974 426 Gene3D G3DSA:3.40.50.10300 192 425 8.3E-52 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CFK41_RS09495 61007459b2c020a0433047e0f65a1974 426 Pfam PF02441 Flavoprotein 12 180 1.8E-34 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CFK41_RS09495 61007459b2c020a0433047e0f65a1974 426 Gene3D G3DSA:3.40.50.1950 3 191 3.5E-46 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CFK41_RS06625 c34ae9f6836d4ba99d0a18669883b906 258 Pfam PF12706 Beta-lactamase superfamily domain 35 226 2.8E-22 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS06625 c34ae9f6836d4ba99d0a18669883b906 258 SUPERFAMILY SSF56281 1 257 3.14E-48 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS06625 c34ae9f6836d4ba99d0a18669883b906 258 Gene3D G3DSA:3.60.15.10 1 258 4.3E-42 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS14645 22088a6d55674e312eb3ec115dfa35fb 405 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 41 153 3.3E-13 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CFK41_RS14645 22088a6d55674e312eb3ec115dfa35fb 405 Gene3D G3DSA:3.40.50.720 224 395 5.9E-10 T 28-03-2018 CFK41_RS14645 22088a6d55674e312eb3ec115dfa35fb 405 SMART SM01002 175 336 1.1E-8 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CFK41_RS14645 22088a6d55674e312eb3ec115dfa35fb 405 SUPERFAMILY SSF51735 172 342 2.17E-15 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS14645 22088a6d55674e312eb3ec115dfa35fb 405 SMART SM01003 35 172 1.1E-22 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CFK41_RS14645 22088a6d55674e312eb3ec115dfa35fb 405 SUPERFAMILY SSF52283 37 208 3.66E-29 T 28-03-2018 CFK41_RS14645 22088a6d55674e312eb3ec115dfa35fb 405 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 264 389 2.0E-10 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CFK41_RS14645 22088a6d55674e312eb3ec115dfa35fb 405 Gene3D G3DSA:3.40.50.720 31 223 4.0E-24 T 28-03-2018 CFK41_RS11750 9e4725c7753fdfe0176fb9d099a3721d 100 SUPERFAMILY SSF64376 7 84 1.7E-18 T 28-03-2018 IPR007393 Domain of unknown function DUF448 CFK41_RS11750 9e4725c7753fdfe0176fb9d099a3721d 100 Pfam PF04296 Protein of unknown function (DUF448) 11 87 4.0E-20 T 28-03-2018 IPR007393 Domain of unknown function DUF448 CFK41_RS11750 9e4725c7753fdfe0176fb9d099a3721d 100 Gene3D G3DSA:3.30.1230.10 1 93 2.1E-23 T 28-03-2018 IPR007393 Domain of unknown function DUF448 CFK41_RS08380 fc81a0044f4ed637354c58652d367c36 82 Gene3D G3DSA:1.10.1200.10 2 82 1.2E-19 T 28-03-2018 CFK41_RS08380 fc81a0044f4ed637354c58652d367c36 82 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 38 77 2.0E-13 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CFK41_RS08380 fc81a0044f4ed637354c58652d367c36 82 Pfam PF00550 Phosphopantetheine attachment site 12 77 1.0E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CFK41_RS08380 fc81a0044f4ed637354c58652d367c36 82 Hamap MF_01217 Acyl carrier protein [acpP]. 7 81 16.936 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CFK41_RS08380 fc81a0044f4ed637354c58652d367c36 82 SUPERFAMILY SSF47336 3 80 1.57E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CFK41_RS15005 414aae3334c1165cff59e47ea72a6664 161 Gene3D G3DSA:2.30.110.10 4 159 2.5E-19 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CFK41_RS15005 414aae3334c1165cff59e47ea72a6664 161 Pfam PF16242 Pyridoxamine 5'-phosphate oxidase like 11 151 7.3E-35 T 28-03-2018 CFK41_RS15005 414aae3334c1165cff59e47ea72a6664 161 SUPERFAMILY SSF50475 9 135 3.14E-27 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CFK41_RS03950 3f23b802ee5ccb79e6e55b7265ce86ba 132 TIGRFAM TIGR00333 nrdI: nrdI protein 5 130 7.8E-48 T 28-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI CFK41_RS03950 3f23b802ee5ccb79e6e55b7265ce86ba 132 Gene3D G3DSA:3.40.50.360 4 132 7.2E-27 T 28-03-2018 IPR029039 Flavoprotein-like domain CFK41_RS03950 3f23b802ee5ccb79e6e55b7265ce86ba 132 Hamap MF_00128 Protein NrdI [nrdI]. 3 132 33.37 T 28-03-2018 IPR020852 Ribonucleotide reductase, class Ib, NrdI, bacterial CFK41_RS03950 3f23b802ee5ccb79e6e55b7265ce86ba 132 PIRSF PIRSF005087 1 132 1.4E-52 T 28-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI CFK41_RS03950 3f23b802ee5ccb79e6e55b7265ce86ba 132 Pfam PF07972 NrdI Flavodoxin like 5 123 8.5E-48 T 28-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI CFK41_RS03950 3f23b802ee5ccb79e6e55b7265ce86ba 132 SUPERFAMILY SSF52218 4 131 2.01E-25 T 28-03-2018 IPR029039 Flavoprotein-like domain CFK41_RS05965 382913216a29724760f19842a3ffacf3 374 SUPERFAMILY SSF56176 3 81 5.14E-10 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CFK41_RS05965 382913216a29724760f19842a3ffacf3 374 Gene3D G3DSA:3.30.43.10 1 65 3.2E-20 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CFK41_RS05965 382913216a29724760f19842a3ffacf3 374 SUPERFAMILY SSF56194 241 372 2.62E-32 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CFK41_RS05965 382913216a29724760f19842a3ffacf3 374 Gene3D G3DSA:3.90.78.10 264 374 1.9E-37 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CFK41_RS05965 382913216a29724760f19842a3ffacf3 374 SUPERFAMILY SSF56176 110 214 9.16E-17 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CFK41_RS05965 382913216a29724760f19842a3ffacf3 374 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 374 67.798 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CFK41_RS05965 382913216a29724760f19842a3ffacf3 374 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 243 369 2.3E-36 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CFK41_RS05965 382913216a29724760f19842a3ffacf3 374 Gene3D G3DSA:3.30.465.10 97 256 1.0E-47 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CFK41_RS05965 382913216a29724760f19842a3ffacf3 374 Pfam PF01565 FAD binding domain 18 64 2.6E-7 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CFK41_RS05965 382913216a29724760f19842a3ffacf3 374 Pfam PF01565 FAD binding domain 81 166 1.4E-9 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CFK41_RS07955 e1284eab8edcc045551e256b7d3c6362 499 Gene3D G3DSA:3.50.50.60 2 483 4.4E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS07955 e1284eab8edcc045551e256b7d3c6362 499 Pfam PF13450 NAD(P)-binding Rossmann-like domain 13 62 2.0E-9 T 28-03-2018 CFK41_RS07955 e1284eab8edcc045551e256b7d3c6362 499 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 304 325 4.5E-7 T 28-03-2018 CFK41_RS07955 e1284eab8edcc045551e256b7d3c6362 499 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 4.5E-7 T 28-03-2018 CFK41_RS07955 e1284eab8edcc045551e256b7d3c6362 499 SUPERFAMILY SSF51905 452 483 1.78E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS07955 e1284eab8edcc045551e256b7d3c6362 499 SUPERFAMILY SSF51905 10 312 1.78E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS11360 b5555a60ea2dab5712a2555d1bc2433b 193 Pfam PF01066 CDP-alcohol phosphatidyltransferase 12 75 1.4E-13 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CFK41_RS11360 b5555a60ea2dab5712a2555d1bc2433b 193 PIRSF PIRSF000847 8 184 2.4E-34 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CFK41_RS11360 b5555a60ea2dab5712a2555d1bc2433b 193 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 53 75 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CFK41_RS13820 b11000921625513efcc87e7285546549 633 Pfam PF00905 Penicillin binding protein transpeptidase domain 354 631 2.5E-39 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CFK41_RS13820 b11000921625513efcc87e7285546549 633 Pfam PF03717 Penicillin-binding Protein dimerisation domain 155 315 2.4E-5 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CFK41_RS13820 b11000921625513efcc87e7285546549 633 SUPERFAMILY SSF56519 149 333 1.22E-13 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CFK41_RS13820 b11000921625513efcc87e7285546549 633 SUPERFAMILY SSF56601 290 632 1.24E-55 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CFK41_RS13820 b11000921625513efcc87e7285546549 633 Gene3D G3DSA:3.40.710.10 336 633 5.0E-54 T 28-03-2018 CFK41_RS13820 b11000921625513efcc87e7285546549 633 Gene3D G3DSA:3.90.1310.10 218 335 1.1E-7 T 28-03-2018 CFK41_RS04845 055d009c63288092038a6f71f9ebe302 241 Gene3D G3DSA:3.60.15.10 1 216 6.8E-25 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS04845 055d009c63288092038a6f71f9ebe302 241 SUPERFAMILY SSF56281 8 207 3.8E-22 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS04845 055d009c63288092038a6f71f9ebe302 241 Pfam PF13483 Beta-lactamase superfamily domain 3 201 1.5E-15 T 28-03-2018 CFK41_RS04845 055d009c63288092038a6f71f9ebe302 241 SMART SM00849 7 201 7.2E-4 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS02655 ec97807920d396291b2c3ad469025207 394 SUPERFAMILY SSF50129 2 189 4.57E-55 T 28-03-2018 IPR011032 GroES-like CFK41_RS02655 ec97807920d396291b2c3ad469025207 394 Gene3D G3DSA:3.40.50.720 179 343 4.0E-27 T 28-03-2018 CFK41_RS02655 ec97807920d396291b2c3ad469025207 394 Pfam PF00107 Zinc-binding dehydrogenase 189 255 2.0E-10 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CFK41_RS02655 ec97807920d396291b2c3ad469025207 394 SUPERFAMILY SSF51735 156 349 1.87E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS02655 ec97807920d396291b2c3ad469025207 394 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CFK41_RS02655 ec97807920d396291b2c3ad469025207 394 Pfam PF13823 Alcohol dehydrogenase GroES-associated 2 23 6.6E-8 T 28-03-2018 IPR027399 Alcohol dehydrogenase GroES-associated CFK41_RS02655 ec97807920d396291b2c3ad469025207 394 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 141 1.1E-26 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CFK41_RS02655 ec97807920d396291b2c3ad469025207 394 Gene3D G3DSA:3.90.180.10 1 178 1.2E-43 T 28-03-2018 CFK41_RS04545 3ba31c3e55e57c448314c3b3767790ee 395 SUPERFAMILY SSF52540 6 220 1.15E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS04545 3ba31c3e55e57c448314c3b3767790ee 395 Pfam PF03143 Elongation factor Tu C-terminal domain 299 393 2.1E-32 T 28-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal CFK41_RS04545 3ba31c3e55e57c448314c3b3767790ee 395 SUPERFAMILY SSF50465 299 394 2.82E-35 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CFK41_RS04545 3ba31c3e55e57c448314c3b3767790ee 395 Gene3D G3DSA:3.40.50.300 2 76 1.1E-10 T 28-03-2018 CFK41_RS04545 3ba31c3e55e57c448314c3b3767790ee 395 PRINTS PR00315 GTP-binding elongation factor signature 96 107 2.6E-23 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS04545 3ba31c3e55e57c448314c3b3767790ee 395 PRINTS PR00315 GTP-binding elongation factor signature 60 68 2.6E-23 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS04545 3ba31c3e55e57c448314c3b3767790ee 395 PRINTS PR00315 GTP-binding elongation factor signature 80 90 2.6E-23 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS04545 3ba31c3e55e57c448314c3b3767790ee 395 PRINTS PR00315 GTP-binding elongation factor signature 133 142 2.6E-23 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS04545 3ba31c3e55e57c448314c3b3767790ee 395 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.6E-23 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS04545 3ba31c3e55e57c448314c3b3767790ee 395 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CFK41_RS04545 3ba31c3e55e57c448314c3b3767790ee 395 Gene3D G3DSA:2.40.30.10 193 299 3.1E-30 T 28-03-2018 CFK41_RS04545 3ba31c3e55e57c448314c3b3767790ee 395 Gene3D G3DSA:3.40.50.300 77 192 3.0E-31 T 28-03-2018 CFK41_RS04545 3ba31c3e55e57c448314c3b3767790ee 395 SUPERFAMILY SSF50447 206 302 1.23E-29 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CFK41_RS04545 3ba31c3e55e57c448314c3b3767790ee 395 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 395 57.346 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CFK41_RS04545 3ba31c3e55e57c448314c3b3767790ee 395 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 394 3.1E-209 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CFK41_RS04545 3ba31c3e55e57c448314c3b3767790ee 395 Pfam PF00009 Elongation factor Tu GTP binding domain 10 202 2.0E-55 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CFK41_RS04545 3ba31c3e55e57c448314c3b3767790ee 395 Gene3D G3DSA:2.40.30.10 301 394 5.2E-32 T 28-03-2018 CFK41_RS04545 3ba31c3e55e57c448314c3b3767790ee 395 Pfam PF03144 Elongation factor Tu domain 2 226 294 9.3E-16 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CFK41_RS04545 3ba31c3e55e57c448314c3b3767790ee 395 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 157 3.7E-13 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CFK41_RS06745 345d40e0b67be12121f077a4323d2123 263 SUPERFAMILY SSF51735 7 240 4.45E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS06745 345d40e0b67be12121f077a4323d2123 263 Gene3D G3DSA:3.40.50.720 1 250 3.6E-38 T 28-03-2018 CFK41_RS06745 345d40e0b67be12121f077a4323d2123 263 Pfam PF01370 NAD dependent epimerase/dehydratase family 10 168 2.9E-24 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CFK41_RS06745 345d40e0b67be12121f077a4323d2123 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 128 156 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CFK41_RS14895 b424004fc6bd2f2ed67c2d791f86a316 206 SUPERFAMILY SSF55811 13 193 1.62E-43 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CFK41_RS14895 b424004fc6bd2f2ed67c2d791f86a316 206 Pfam PF00293 NUDIX domain 40 179 2.8E-15 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CFK41_RS14895 b424004fc6bd2f2ed67c2d791f86a316 206 PIRSF PIRSF018427 2 203 1.5E-47 T 28-03-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 CFK41_RS14895 b424004fc6bd2f2ed67c2d791f86a316 206 Gene3D G3DSA:3.90.79.10 4 204 4.4E-25 T 28-03-2018 CFK41_RS14895 b424004fc6bd2f2ed67c2d791f86a316 206 Hamap MF_00202 Isopentenyl-diphosphate Delta-isomerase [idi]. 13 202 33.5 T 28-03-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 CFK41_RS14895 b424004fc6bd2f2ed67c2d791f86a316 206 TIGRFAM TIGR02150 IPP_isom_1: isopentenyl-diphosphate delta-isomerase 15 189 7.8E-38 T 28-03-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 CFK41_RS01385 c259362b5f6152e8757acc8446e908ab 690 Gene3D G3DSA:3.40.225.10 307 408 0.018 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CFK41_RS01385 c259362b5f6152e8757acc8446e908ab 690 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 433 450 1.2E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS01385 c259362b5f6152e8757acc8446e908ab 690 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 506 517 1.2E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS01385 c259362b5f6152e8757acc8446e908ab 690 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 554 570 1.2E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS01385 c259362b5f6152e8757acc8446e908ab 690 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 580 599 1.2E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS01385 c259362b5f6152e8757acc8446e908ab 690 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 601 618 1.2E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS01385 c259362b5f6152e8757acc8446e908ab 690 SMART SM01007 20 222 2.7E-32 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CFK41_RS01385 c259362b5f6152e8757acc8446e908ab 690 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 506 517 3.5E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS01385 c259362b5f6152e8757acc8446e908ab 690 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 560 568 3.5E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS01385 c259362b5f6152e8757acc8446e908ab 690 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 580 599 3.5E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS01385 c259362b5f6152e8757acc8446e908ab 690 SUPERFAMILY SSF51735 425 687 3.4E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS01385 c259362b5f6152e8757acc8446e908ab 690 TIGRFAM TIGR02632 RhaD_aldol-ADH: rhamnulose-1-phosphate aldolase/alcohol dehydrogenase 18 690 0.0 T 28-03-2018 IPR013454 Bifunctional rhamnulose-1-phosphate aldolase/alcohol dehydrogenase CFK41_RS01385 c259362b5f6152e8757acc8446e908ab 690 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 23 211 1.7E-22 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CFK41_RS01385 c259362b5f6152e8757acc8446e908ab 690 Gene3D G3DSA:3.40.225.10 12 252 2.2E-36 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CFK41_RS01385 c259362b5f6152e8757acc8446e908ab 690 SUPERFAMILY SSF53639 19 218 9.22E-30 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CFK41_RS01385 c259362b5f6152e8757acc8446e908ab 690 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 441 684 4.7E-45 T 28-03-2018 CFK41_RS01385 c259362b5f6152e8757acc8446e908ab 690 Gene3D G3DSA:3.40.50.720 409 687 4.4E-53 T 28-03-2018 CFK41_RS13145 fbb4468cf13e38272fb4a5db17afc5c2 682 Gene3D G3DSA:3.30.200.20 14 109 2.5E-19 T 28-03-2018 CFK41_RS13145 fbb4468cf13e38272fb4a5db17afc5c2 682 Pfam PF00069 Protein kinase domain 28 287 2.6E-37 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CFK41_RS13145 fbb4468cf13e38272fb4a5db17afc5c2 682 SMART SM00220 28 297 2.7E-37 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CFK41_RS13145 fbb4468cf13e38272fb4a5db17afc5c2 682 Gene3D G3DSA:1.10.510.10 110 464 1.6E-32 T 28-03-2018 CFK41_RS13145 fbb4468cf13e38272fb4a5db17afc5c2 682 SUPERFAMILY SSF56112 379 451 3.2E-56 T 28-03-2018 IPR011009 Protein kinase-like domain CFK41_RS13145 fbb4468cf13e38272fb4a5db17afc5c2 682 SUPERFAMILY SSF56112 27 294 3.2E-56 T 28-03-2018 IPR011009 Protein kinase-like domain CFK41_RS13145 fbb4468cf13e38272fb4a5db17afc5c2 682 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 34 56 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CFK41_RS13145 fbb4468cf13e38272fb4a5db17afc5c2 682 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 146 158 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CFK41_RS09415 dbba34ca60e12bf367b5dfb8c9afd576 857 ProSitePatterns PS00333 ATP-dependent DNA ligase signature 2. 710 734 - T 28-03-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 CFK41_RS09415 dbba34ca60e12bf367b5dfb8c9afd576 857 Pfam PF01068 ATP dependent DNA ligase domain 538 734 1.4E-33 T 28-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 CFK41_RS09415 dbba34ca60e12bf367b5dfb8c9afd576 857 Pfam PF13298 DNA polymerase Ligase (LigD) 356 433 8.3E-31 T 28-03-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain CFK41_RS09415 dbba34ca60e12bf367b5dfb8c9afd576 857 SUPERFAMILY SSF56091 535 734 4.32E-41 T 28-03-2018 CFK41_RS09415 dbba34ca60e12bf367b5dfb8c9afd576 857 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 16 267 3.1E-75 T 28-03-2018 IPR014145 DNA ligase D, polymerase domain CFK41_RS09415 dbba34ca60e12bf367b5dfb8c9afd576 857 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 539 854 1.3E-77 T 28-03-2018 IPR014146 DNA ligase D, ligase domain CFK41_RS09415 dbba34ca60e12bf367b5dfb8c9afd576 857 Gene3D G3DSA:3.30.1490.70 679 724 3.0E-14 T 28-03-2018 CFK41_RS09415 dbba34ca60e12bf367b5dfb8c9afd576 857 Pfam PF04679 ATP dependent DNA ligase C terminal region 753 848 7.1E-25 T 28-03-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 CFK41_RS09415 dbba34ca60e12bf367b5dfb8c9afd576 857 SUPERFAMILY SSF50249 738 854 3.26E-29 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS09415 dbba34ca60e12bf367b5dfb8c9afd576 857 Gene3D G3DSA:3.30.470.30 508 678 1.3E-31 T 28-03-2018 CFK41_RS09415 dbba34ca60e12bf367b5dfb8c9afd576 857 Gene3D G3DSA:2.40.50.140 725 850 1.6E-34 T 28-03-2018 CFK41_RS09415 dbba34ca60e12bf367b5dfb8c9afd576 857 TIGRFAM TIGR02777 LigD_PE_dom: DNA ligase D, 3'-phosphoesterase domain 316 433 9.0E-44 T 28-03-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain CFK41_RS16605 3b58dcca12020e3aec56b81280a557ad 187 Gene3D G3DSA:1.20.120.450 3 186 1.3E-24 T 28-03-2018 CFK41_RS16605 3b58dcca12020e3aec56b81280a557ad 187 SUPERFAMILY SSF109854 73 183 3.21E-14 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CFK41_RS16605 3b58dcca12020e3aec56b81280a557ad 187 Pfam PF12867 DinB superfamily 14 176 3.9E-15 T 28-03-2018 IPR024775 DinB-like domain CFK41_RS09625 a01068e3ceecda47b44a19054a7402fa 273 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 178 196 - T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CFK41_RS09625 a01068e3ceecda47b44a19054a7402fa 273 SUPERFAMILY SSF55920 17 260 3.79E-60 T 28-03-2018 IPR000994 Peptidase M24 CFK41_RS09625 a01068e3ceecda47b44a19054a7402fa 273 Gene3D G3DSA:3.90.230.10 5 271 1.5E-57 T 28-03-2018 CFK41_RS09625 a01068e3ceecda47b44a19054a7402fa 273 Pfam PF00557 Metallopeptidase family M24 20 253 1.2E-36 T 28-03-2018 IPR000994 Peptidase M24 CFK41_RS09625 a01068e3ceecda47b44a19054a7402fa 273 Hamap MF_01974 Methionine aminopeptidase [map]. 9 262 29.822 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CFK41_RS09625 a01068e3ceecda47b44a19054a7402fa 273 PRINTS PR00599 Methionine aminopeptidase-1 signature 203 215 2.9E-14 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CFK41_RS09625 a01068e3ceecda47b44a19054a7402fa 273 PRINTS PR00599 Methionine aminopeptidase-1 signature 172 184 2.9E-14 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CFK41_RS09625 a01068e3ceecda47b44a19054a7402fa 273 PRINTS PR00599 Methionine aminopeptidase-1 signature 80 93 2.9E-14 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CFK41_RS09625 a01068e3ceecda47b44a19054a7402fa 273 PRINTS PR00599 Methionine aminopeptidase-1 signature 102 118 2.9E-14 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CFK41_RS09625 a01068e3ceecda47b44a19054a7402fa 273 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 17 261 3.5E-61 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CFK41_RS05950 2f533e675477535db4337a44100fcd17 56 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 8 56 18.969 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS05950 2f533e675477535db4337a44100fcd17 56 SUPERFAMILY SSF57829 5 56 2.75E-19 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CFK41_RS05950 2f533e675477535db4337a44100fcd17 56 ProSitePatterns PS00582 Ribosomal protein L33 signature. 24 43 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS05950 2f533e675477535db4337a44100fcd17 56 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 8 56 2.4E-20 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS05950 2f533e675477535db4337a44100fcd17 56 Pfam PF00471 Ribosomal protein L33 11 56 1.2E-22 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS09795 0ba71b2ddf11ad18a2ce8a488effed28 704 SMART SM00220 19 281 4.5E-62 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CFK41_RS09795 0ba71b2ddf11ad18a2ce8a488effed28 704 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 138 150 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CFK41_RS09795 0ba71b2ddf11ad18a2ce8a488effed28 704 Pfam PF00069 Protein kinase domain 19 271 6.2E-49 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CFK41_RS09795 0ba71b2ddf11ad18a2ce8a488effed28 704 Pfam PF03793 PASTA domain 445 506 2.5E-15 T 28-03-2018 IPR005543 PASTA domain CFK41_RS09795 0ba71b2ddf11ad18a2ce8a488effed28 704 Pfam PF03793 PASTA domain 579 638 1.2E-9 T 28-03-2018 IPR005543 PASTA domain CFK41_RS09795 0ba71b2ddf11ad18a2ce8a488effed28 704 Pfam PF03793 PASTA domain 644 703 7.1E-10 T 28-03-2018 IPR005543 PASTA domain CFK41_RS09795 0ba71b2ddf11ad18a2ce8a488effed28 704 Pfam PF03793 PASTA domain 513 572 7.5E-10 T 28-03-2018 IPR005543 PASTA domain CFK41_RS09795 0ba71b2ddf11ad18a2ce8a488effed28 704 SUPERFAMILY SSF56112 16 273 7.62E-74 T 28-03-2018 IPR011009 Protein kinase-like domain CFK41_RS09795 0ba71b2ddf11ad18a2ce8a488effed28 704 SMART SM00740 574 639 2.4E-7 T 28-03-2018 IPR005543 PASTA domain CFK41_RS09795 0ba71b2ddf11ad18a2ce8a488effed28 704 SMART SM00740 440 506 6.3E-13 T 28-03-2018 IPR005543 PASTA domain CFK41_RS09795 0ba71b2ddf11ad18a2ce8a488effed28 704 SMART SM00740 507 573 7.9E-7 T 28-03-2018 IPR005543 PASTA domain CFK41_RS09795 0ba71b2ddf11ad18a2ce8a488effed28 704 SMART SM00740 640 703 4.9E-6 T 28-03-2018 IPR005543 PASTA domain CFK41_RS09795 0ba71b2ddf11ad18a2ce8a488effed28 704 Gene3D G3DSA:3.30.200.20 3 87 8.5E-18 T 28-03-2018 CFK41_RS09795 0ba71b2ddf11ad18a2ce8a488effed28 704 Gene3D G3DSA:1.10.510.10 88 371 2.2E-50 T 28-03-2018 CFK41_RS16910 dda3d2a5462946b5287323304ed59dfb 297 Gene3D G3DSA:2.60.120.10 22 124 3.6E-31 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CFK41_RS16910 dda3d2a5462946b5287323304ed59dfb 297 TIGRFAM TIGR04378 myo_inos_iolB: 5-deoxy-glucuronate isomerase 28 280 9.4E-76 T 28-03-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 CFK41_RS16910 dda3d2a5462946b5287323304ed59dfb 297 PIRSF PIRSF036628 6 285 1.2E-78 T 28-03-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 CFK41_RS16910 dda3d2a5462946b5287323304ed59dfb 297 Gene3D G3DSA:2.60.120.10 125 284 8.1E-61 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CFK41_RS16910 dda3d2a5462946b5287323304ed59dfb 297 Pfam PF04962 KduI/IolB family 23 279 8.4E-79 T 28-03-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 CFK41_RS16910 dda3d2a5462946b5287323304ed59dfb 297 SUPERFAMILY SSF51182 28 263 1.47E-51 T 28-03-2018 IPR011051 RmlC-like cupin domain CFK41_RS05065 401ab4cfbc7fab4099dd7c10de04502a 311 Gene3D G3DSA:3.40.50.1820 3 289 2.3E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS05065 401ab4cfbc7fab4099dd7c10de04502a 311 Pfam PF12146 Serine aminopeptidase, S33 33 267 5.1E-12 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CFK41_RS05065 401ab4cfbc7fab4099dd7c10de04502a 311 SUPERFAMILY SSF53474 180 272 2.89E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS05065 401ab4cfbc7fab4099dd7c10de04502a 311 SUPERFAMILY SSF53474 8 151 2.89E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS12535 ec44f4dc8e47bd32fa2361defd798b71 406 Hamap MF_00020 Acetate kinase [ackA]. 1 405 157.1 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CFK41_RS12535 ec44f4dc8e47bd32fa2361defd798b71 406 TIGRFAM TIGR00016 ackA: acetate kinase 7 398 8.6E-124 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CFK41_RS12535 ec44f4dc8e47bd32fa2361defd798b71 406 PRINTS PR00471 Acetate kinase family signature 328 344 2.6E-32 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CFK41_RS12535 ec44f4dc8e47bd32fa2361defd798b71 406 PRINTS PR00471 Acetate kinase family signature 9 20 2.6E-32 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CFK41_RS12535 ec44f4dc8e47bd32fa2361defd798b71 406 PRINTS PR00471 Acetate kinase family signature 177 190 2.6E-32 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CFK41_RS12535 ec44f4dc8e47bd32fa2361defd798b71 406 PRINTS PR00471 Acetate kinase family signature 383 395 2.6E-32 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CFK41_RS12535 ec44f4dc8e47bd32fa2361defd798b71 406 PRINTS PR00471 Acetate kinase family signature 306 319 2.6E-32 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CFK41_RS12535 ec44f4dc8e47bd32fa2361defd798b71 406 PIRSF PIRSF000722 5 405 6.6E-128 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CFK41_RS12535 ec44f4dc8e47bd32fa2361defd798b71 406 Pfam PF00871 Acetokinase family 9 396 2.0E-127 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CFK41_RS12535 ec44f4dc8e47bd32fa2361defd798b71 406 Gene3D G3DSA:3.30.420.40 8 199 2.8E-63 T 28-03-2018 CFK41_RS12535 ec44f4dc8e47bd32fa2361defd798b71 406 SUPERFAMILY SSF53067 161 403 4.24E-73 T 28-03-2018 CFK41_RS12535 ec44f4dc8e47bd32fa2361defd798b71 406 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 9 20 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CFK41_RS12535 ec44f4dc8e47bd32fa2361defd798b71 406 SUPERFAMILY SSF53067 8 198 1.39E-56 T 28-03-2018 CFK41_RS12535 ec44f4dc8e47bd32fa2361defd798b71 406 Gene3D G3DSA:3.30.420.40 203 405 1.5E-71 T 28-03-2018 CFK41_RS14890 d7ee645362dc98084199a4c4c8eac164 176 SMART SM00347 44 148 3.3E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS14890 d7ee645362dc98084199a4c4c8eac164 176 Gene3D G3DSA:1.10.10.10 3 166 3.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS14890 d7ee645362dc98084199a4c4c8eac164 176 Pfam PF12802 MarR family 51 112 6.3E-10 T 28-03-2018 CFK41_RS14890 d7ee645362dc98084199a4c4c8eac164 176 SUPERFAMILY SSF46785 24 164 3.36E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS00340 5254dac5b83222fe0525b6ff94d835fa 249 Gene3D G3DSA:3.90.1200.10 71 219 3.5E-21 T 28-03-2018 CFK41_RS00340 5254dac5b83222fe0525b6ff94d835fa 249 SUPERFAMILY SSF56112 4 238 2.77E-27 T 28-03-2018 IPR011009 Protein kinase-like domain CFK41_RS00340 5254dac5b83222fe0525b6ff94d835fa 249 Pfam PF01636 Phosphotransferase enzyme family 32 212 1.4E-20 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CFK41_RS08725 705d4711e776a4d12af8c316244a868d 665 Gene3D G3DSA:1.10.10.10 324 388 0.0012 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS08725 705d4711e776a4d12af8c316244a868d 665 Pfam PF13280 WYL domain 139 302 6.1E-22 T 28-03-2018 IPR026881 WYL domain CFK41_RS08725 705d4711e776a4d12af8c316244a868d 665 Pfam PF13280 WYL domain 503 658 5.8E-14 T 28-03-2018 IPR026881 WYL domain CFK41_RS02985 9fa51f5ef4e5ba2f91d745f8f6a8aeb3 222 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 58 72 7.1E-9 T 28-03-2018 CFK41_RS02985 9fa51f5ef4e5ba2f91d745f8f6a8aeb3 222 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 89 105 7.1E-9 T 28-03-2018 CFK41_RS02985 9fa51f5ef4e5ba2f91d745f8f6a8aeb3 222 Gene3D G3DSA:3.40.50.880 11 206 2.5E-55 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS02985 9fa51f5ef4e5ba2f91d745f8f6a8aeb3 222 PRINTS PR00096 Glutamine amidotransferase superfamily signature 89 100 1.6E-14 T 28-03-2018 CFK41_RS02985 9fa51f5ef4e5ba2f91d745f8f6a8aeb3 222 PRINTS PR00096 Glutamine amidotransferase superfamily signature 179 192 1.6E-14 T 28-03-2018 CFK41_RS02985 9fa51f5ef4e5ba2f91d745f8f6a8aeb3 222 PRINTS PR00096 Glutamine amidotransferase superfamily signature 61 70 1.6E-14 T 28-03-2018 CFK41_RS02985 9fa51f5ef4e5ba2f91d745f8f6a8aeb3 222 Pfam PF00117 Glutamine amidotransferase class-I 15 200 4.6E-49 T 28-03-2018 IPR017926 Glutamine amidotransferase CFK41_RS02985 9fa51f5ef4e5ba2f91d745f8f6a8aeb3 222 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 13 201 2.1E-59 T 28-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CFK41_RS02985 9fa51f5ef4e5ba2f91d745f8f6a8aeb3 222 PRINTS PR00097 Anthranilate synthase component II signature 114 122 4.9E-33 T 28-03-2018 CFK41_RS02985 9fa51f5ef4e5ba2f91d745f8f6a8aeb3 222 PRINTS PR00097 Anthranilate synthase component II signature 179 192 4.9E-33 T 28-03-2018 CFK41_RS02985 9fa51f5ef4e5ba2f91d745f8f6a8aeb3 222 PRINTS PR00097 Anthranilate synthase component II signature 89 100 4.9E-33 T 28-03-2018 CFK41_RS02985 9fa51f5ef4e5ba2f91d745f8f6a8aeb3 222 PRINTS PR00097 Anthranilate synthase component II signature 13 27 4.9E-33 T 28-03-2018 CFK41_RS02985 9fa51f5ef4e5ba2f91d745f8f6a8aeb3 222 PRINTS PR00097 Anthranilate synthase component II signature 134 146 4.9E-33 T 28-03-2018 CFK41_RS02985 9fa51f5ef4e5ba2f91d745f8f6a8aeb3 222 PRINTS PR00097 Anthranilate synthase component II signature 61 70 4.9E-33 T 28-03-2018 CFK41_RS02985 9fa51f5ef4e5ba2f91d745f8f6a8aeb3 222 SUPERFAMILY SSF52317 12 204 3.44E-53 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS04570 7baee299ea7815b2affa5fe3dfc2366a 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 26.779 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04570 7baee299ea7815b2affa5fe3dfc2366a 102 Gene3D G3DSA:3.30.70.600 4 102 1.3E-35 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CFK41_RS04570 7baee299ea7815b2affa5fe3dfc2366a 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 4.3E-45 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04570 7baee299ea7815b2affa5fe3dfc2366a 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 28-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04570 7baee299ea7815b2affa5fe3dfc2366a 102 SMART SM01403 7 101 3.7E-55 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CFK41_RS04570 7baee299ea7815b2affa5fe3dfc2366a 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 3.3E-21 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04570 7baee299ea7815b2affa5fe3dfc2366a 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 3.3E-21 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04570 7baee299ea7815b2affa5fe3dfc2366a 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 3.3E-21 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04570 7baee299ea7815b2affa5fe3dfc2366a 102 SUPERFAMILY SSF54999 5 102 3.4E-37 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CFK41_RS04570 7baee299ea7815b2affa5fe3dfc2366a 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 1.1E-34 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CFK41_RS14475 eac2372a11d22b52c24b04d04148dae8 495 Gene3D G3DSA:3.60.60.10 1 316 5.0E-52 T 28-03-2018 CFK41_RS14475 eac2372a11d22b52c24b04d04148dae8 495 Pfam PF03577 Peptidase family C69 3 427 8.2E-165 T 28-03-2018 IPR005322 Peptidase C69, dipeptidase A GO:0006508|GO:0016805 CFK41_RS08155 b7ae056134b461285fb91e63a631c800 334 SMART SM00382 50 237 2.7E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS08155 b7ae056134b461285fb91e63a631c800 334 Gene3D G3DSA:3.40.50.300 1 282 5.7E-51 T 28-03-2018 CFK41_RS08155 b7ae056134b461285fb91e63a631c800 334 SUPERFAMILY SSF52540 39 245 3.34E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS08155 b7ae056134b461285fb91e63a631c800 334 Pfam PF00005 ABC transporter 42 185 1.5E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS17390 41e501741482f028f57b872f7f6254f1 209 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 45 204 2.2E-18 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS17390 41e501741482f028f57b872f7f6254f1 209 Gene3D G3DSA:1.10.10.10 115 208 4.2E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS17390 41e501741482f028f57b872f7f6254f1 209 Pfam PF04542 Sigma-70 region 2 50 116 1.9E-15 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS17390 41e501741482f028f57b872f7f6254f1 209 Pfam PF08281 Sigma-70, region 4 149 196 5.1E-11 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS17390 41e501741482f028f57b872f7f6254f1 209 SUPERFAMILY SSF88946 33 126 8.24E-22 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS17390 41e501741482f028f57b872f7f6254f1 209 SUPERFAMILY SSF88659 144 205 2.83E-12 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS17390 41e501741482f028f57b872f7f6254f1 209 Gene3D G3DSA:1.10.1740.10 29 114 6.0E-21 T 28-03-2018 CFK41_RS06565 96a592a97640b00b6f89669339c33a31 325 SUPERFAMILY SSF161098 96 305 1.09E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS06565 96a592a97640b00b6f89669339c33a31 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 322 3.7E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS06565 96a592a97640b00b6f89669339c33a31 325 Gene3D G3DSA:1.10.3720.10 1 311 1.2E-32 T 28-03-2018 CFK41_RS00625 3ae337ecc085d417d45f255c75c57918 377 Pfam PF01636 Phosphotransferase enzyme family 64 315 5.9E-19 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CFK41_RS00625 3ae337ecc085d417d45f255c75c57918 377 SUPERFAMILY SSF56112 64 355 4.96E-28 T 28-03-2018 IPR011009 Protein kinase-like domain CFK41_RS00625 3ae337ecc085d417d45f255c75c57918 377 Gene3D G3DSA:3.90.1200.10 142 362 8.7E-21 T 28-03-2018 CFK41_RS12655 c03b40365dda617020560e789698aed5 366 Gene3D G3DSA:3.20.20.70 31 366 2.5E-79 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS12655 c03b40365dda617020560e789698aed5 366 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 35 366 39.594 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CFK41_RS12655 c03b40365dda617020560e789698aed5 366 SMART SM00729 44 240 1.2E-8 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CFK41_RS12655 c03b40365dda617020560e789698aed5 366 SUPERFAMILY SSF102114 36 314 4.58E-69 T 28-03-2018 CFK41_RS12655 c03b40365dda617020560e789698aed5 366 Pfam PF04055 Radical SAM superfamily 49 210 1.4E-31 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CFK41_RS12655 c03b40365dda617020560e789698aed5 366 Pfam PF06463 Molybdenum Cofactor Synthesis C 217 348 8.7E-33 T 28-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 CFK41_RS12655 c03b40365dda617020560e789698aed5 366 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 50 61 - T 28-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 CFK41_RS12655 c03b40365dda617020560e789698aed5 366 Pfam PF13353 4Fe-4S single cluster domain 53 159 1.1E-4 T 28-03-2018 CFK41_RS12655 c03b40365dda617020560e789698aed5 366 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 35 366 3.6E-108 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CFK41_RS07460 4c89529b91f70a6041952269e2d5b684 163 Gene3D G3DSA:3.40.50.620 1 161 8.8E-29 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS07460 4c89529b91f70a6041952269e2d5b684 163 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 4 157 1.4E-45 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CFK41_RS07460 4c89529b91f70a6041952269e2d5b684 163 SUPERFAMILY SSF52374 1 157 3.22E-33 T 28-03-2018 CFK41_RS07460 4c89529b91f70a6041952269e2d5b684 163 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 161 27.411 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CFK41_RS07460 4c89529b91f70a6041952269e2d5b684 163 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 55 1.1E-12 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CFK41_RS07460 4c89529b91f70a6041952269e2d5b684 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 1.0E-12 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CFK41_RS07460 4c89529b91f70a6041952269e2d5b684 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 1.0E-12 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CFK41_RS07460 4c89529b91f70a6041952269e2d5b684 163 Pfam PF01467 Cytidylyltransferase-like 6 136 7.7E-12 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CFK41_RS13490 c2833890be9247cc93ab8612e6b1ebdb 324 SUPERFAMILY SSF55021 186 284 7.12E-23 T 28-03-2018 CFK41_RS13490 c2833890be9247cc93ab8612e6b1ebdb 324 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 232 239 - T 28-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CFK41_RS13490 c2833890be9247cc93ab8612e6b1ebdb 324 Gene3D G3DSA:3.40.190.10 100 180 3.1E-24 T 28-03-2018 CFK41_RS13490 c2833890be9247cc93ab8612e6b1ebdb 324 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 167 189 - T 28-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CFK41_RS13490 c2833890be9247cc93ab8612e6b1ebdb 324 Gene3D G3DSA:3.30.70.260 194 291 9.0E-29 T 28-03-2018 CFK41_RS13490 c2833890be9247cc93ab8612e6b1ebdb 324 SUPERFAMILY SSF53850 1 197 3.47E-44 T 28-03-2018 CFK41_RS13490 c2833890be9247cc93ab8612e6b1ebdb 324 Pfam PF01842 ACT domain 205 270 4.3E-8 T 28-03-2018 IPR002912 ACT domain CFK41_RS13490 c2833890be9247cc93ab8612e6b1ebdb 324 Pfam PF00800 Prephenate dehydratase 4 192 3.0E-46 T 28-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CFK41_RS13490 c2833890be9247cc93ab8612e6b1ebdb 324 Gene3D G3DSA:3.40.190.10 1 99 1.3E-23 T 28-03-2018 CFK41_RS13490 c2833890be9247cc93ab8612e6b1ebdb 324 PIRSF PIRSF001500 1 286 2.1E-57 T 28-03-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CFK41_RS11235 2ada6a5cc2669b0beab93d6d5e9a8310 1069 Gene3D G3DSA:3.40.50.300 27 302 2.2E-19 T 28-03-2018 CFK41_RS11235 2ada6a5cc2669b0beab93d6d5e9a8310 1069 Gene3D G3DSA:3.90.320.10 691 1004 2.9E-12 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CFK41_RS11235 2ada6a5cc2669b0beab93d6d5e9a8310 1069 Pfam PF13245 AAA domain 35 273 1.0E-5 T 28-03-2018 CFK41_RS11235 2ada6a5cc2669b0beab93d6d5e9a8310 1069 Gene3D G3DSA:1.10.486.10 426 607 1.5E-9 T 28-03-2018 CFK41_RS11235 2ada6a5cc2669b0beab93d6d5e9a8310 1069 Gene3D G3DSA:3.40.50.300 303 422 7.2E-7 T 28-03-2018 CFK41_RS11235 2ada6a5cc2669b0beab93d6d5e9a8310 1069 Pfam PF12705 PD-(D/E)XK nuclease superfamily 821 1061 6.0E-30 T 28-03-2018 CFK41_RS11235 2ada6a5cc2669b0beab93d6d5e9a8310 1069 SUPERFAMILY SSF52540 696 733 2.22E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11235 2ada6a5cc2669b0beab93d6d5e9a8310 1069 SUPERFAMILY SSF52540 500 664 2.22E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11235 2ada6a5cc2669b0beab93d6d5e9a8310 1069 SUPERFAMILY SSF52540 30 468 2.22E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS08230 330ccad8f022fa2c856be4ef140bd21a 244 Hamap MF_00201 DNA repair protein RecO [recO]. 4 242 25.284 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CFK41_RS08230 330ccad8f022fa2c856be4ef140bd21a 244 SUPERFAMILY SSF50249 4 81 4.8E-21 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS08230 330ccad8f022fa2c856be4ef140bd21a 244 TIGRFAM TIGR00613 reco: DNA repair protein RecO 7 238 1.9E-37 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CFK41_RS08230 330ccad8f022fa2c856be4ef140bd21a 244 Pfam PF02565 Recombination protein O C terminal 88 239 1.9E-26 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CFK41_RS08230 330ccad8f022fa2c856be4ef140bd21a 244 Pfam PF11967 Recombination protein O N terminal 5 81 6.6E-28 T 28-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal CFK41_RS08230 330ccad8f022fa2c856be4ef140bd21a 244 SUPERFAMILY SSF57863 84 234 1.46E-33 T 28-03-2018 CFK41_RS08230 330ccad8f022fa2c856be4ef140bd21a 244 Gene3D G3DSA:2.40.50.140 3 83 8.8E-31 T 28-03-2018 CFK41_RS06795 558445f81f4e11a5340603b27dd42940 434 Gene3D G3DSA:1.20.1250.20 14 209 6.5E-18 T 28-03-2018 CFK41_RS06795 558445f81f4e11a5340603b27dd42940 434 Gene3D G3DSA:1.20.1250.20 216 430 3.1E-8 T 28-03-2018 CFK41_RS06795 558445f81f4e11a5340603b27dd42940 434 Pfam PF05977 Transmembrane secretion effector 16 428 2.0E-36 T 28-03-2018 IPR010290 Transmembrane secretion effector CFK41_RS06795 558445f81f4e11a5340603b27dd42940 434 SUPERFAMILY SSF103473 24 423 4.97E-31 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS14575 f03b47feb686d827d7415a89d7cc42bf 416 SUPERFAMILY SSF51419 54 259 1.83E-21 T 28-03-2018 IPR029066 PLP-binding barrel CFK41_RS14575 f03b47feb686d827d7415a89d7cc42bf 416 Pfam PF14031 Putative serine dehydratase domain 306 402 1.7E-16 T 28-03-2018 IPR026956 D-serine dehydratase-like domain CFK41_RS14575 f03b47feb686d827d7415a89d7cc42bf 416 Pfam PF01168 Alanine racemase, N-terminal domain 54 232 4.2E-10 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CFK41_RS14575 f03b47feb686d827d7415a89d7cc42bf 416 Gene3D G3DSA:3.20.20.10 33 289 9.7E-32 T 28-03-2018 IPR029066 PLP-binding barrel CFK41_RS14575 f03b47feb686d827d7415a89d7cc42bf 416 SMART SM01119 306 403 7.1E-36 T 28-03-2018 IPR026956 D-serine dehydratase-like domain CFK41_RS04510 d6a129b01425dd22f6a171acbd67a3a4 129 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 129 6.0E-46 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04510 d6a129b01425dd22f6a171acbd67a3a4 129 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 3 129 24.139 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04510 d6a129b01425dd22f6a171acbd67a3a4 129 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 6 51 1.5E-17 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04510 d6a129b01425dd22f6a171acbd67a3a4 129 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 63 129 1.5E-28 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04510 d6a129b01425dd22f6a171acbd67a3a4 129 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 64 104 1.0E-10 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04510 d6a129b01425dd22f6a171acbd67a3a4 129 Gene3D G3DSA:1.20.5.710 4 58 3.2E-14 T 28-03-2018 CFK41_RS04510 d6a129b01425dd22f6a171acbd67a3a4 129 SUPERFAMILY SSF54736 58 129 1.19E-23 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CFK41_RS04510 d6a129b01425dd22f6a171acbd67a3a4 129 Gene3D G3DSA:3.30.1390.10 59 129 2.4E-28 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CFK41_RS04510 d6a129b01425dd22f6a171acbd67a3a4 129 SUPERFAMILY SSF48300 5 65 3.66E-14 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS07280 f992c9967b06b44b0273beb23124386d 853 SMART SM00490 281 367 3.3E-15 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS07280 f992c9967b06b44b0273beb23124386d 853 Gene3D G3DSA:3.40.50.300 214 418 5.8E-21 T 28-03-2018 CFK41_RS07280 f992c9967b06b44b0273beb23124386d 853 Pfam PF12029 Domain of unknown function (DUF3516) 378 845 2.5E-171 T 28-03-2018 IPR021904 Protein of unknown function DUF3516 CFK41_RS07280 f992c9967b06b44b0273beb23124386d 853 SUPERFAMILY SSF52540 48 254 7.79E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS07280 f992c9967b06b44b0273beb23124386d 853 SUPERFAMILY SSF52540 287 378 7.79E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS07280 f992c9967b06b44b0273beb23124386d 853 Gene3D G3DSA:3.40.50.300 22 205 2.7E-29 T 28-03-2018 CFK41_RS07280 f992c9967b06b44b0273beb23124386d 853 Pfam PF00270 DEAD/DEAH box helicase 37 184 2.2E-12 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CFK41_RS07280 f992c9967b06b44b0273beb23124386d 853 SMART SM00487 31 212 6.4E-24 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CFK41_RS07280 f992c9967b06b44b0273beb23124386d 853 Pfam PF00271 Helicase conserved C-terminal domain 291 367 7.8E-6 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS09385 b29da89a30bc2b08d408f248918f7abf 543 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 244 1.9E-16 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CFK41_RS09385 b29da89a30bc2b08d408f248918f7abf 543 Gene3D G3DSA:3.40.50.720 1 333 1.2E-37 T 28-03-2018 CFK41_RS09385 b29da89a30bc2b08d408f248918f7abf 543 SUPERFAMILY SSF51735 1 327 2.13E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS06090 be38c2e6ae5ede2dcf4756b193a0ec40 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 308 330 2.7E-31 T 28-03-2018 CFK41_RS06090 be38c2e6ae5ede2dcf4756b193a0ec40 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 195 213 2.7E-31 T 28-03-2018 CFK41_RS06090 be38c2e6ae5ede2dcf4756b193a0ec40 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 279 295 2.7E-31 T 28-03-2018 CFK41_RS06090 be38c2e6ae5ede2dcf4756b193a0ec40 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 2.7E-31 T 28-03-2018 CFK41_RS06090 be38c2e6ae5ede2dcf4756b193a0ec40 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 17 36 2.7E-31 T 28-03-2018 CFK41_RS06090 be38c2e6ae5ede2dcf4756b193a0ec40 481 Gene3D G3DSA:3.30.390.30 371 477 1.1E-24 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CFK41_RS06090 be38c2e6ae5ede2dcf4756b193a0ec40 481 Gene3D G3DSA:3.50.50.60 288 370 3.2E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS06090 be38c2e6ae5ede2dcf4756b193a0ec40 481 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 364 469 3.8E-20 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CFK41_RS06090 be38c2e6ae5ede2dcf4756b193a0ec40 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 48 63 2.3E-48 T 28-03-2018 CFK41_RS06090 be38c2e6ae5ede2dcf4756b193a0ec40 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 195 220 2.3E-48 T 28-03-2018 CFK41_RS06090 be38c2e6ae5ede2dcf4756b193a0ec40 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 280 294 2.3E-48 T 28-03-2018 CFK41_RS06090 be38c2e6ae5ede2dcf4756b193a0ec40 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 323 330 2.3E-48 T 28-03-2018 CFK41_RS06090 be38c2e6ae5ede2dcf4756b193a0ec40 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 424 439 2.3E-48 T 28-03-2018 CFK41_RS06090 be38c2e6ae5ede2dcf4756b193a0ec40 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 16 38 2.3E-48 T 28-03-2018 CFK41_RS06090 be38c2e6ae5ede2dcf4756b193a0ec40 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 168 2.3E-48 T 28-03-2018 CFK41_RS06090 be38c2e6ae5ede2dcf4756b193a0ec40 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 359 380 2.3E-48 T 28-03-2018 CFK41_RS06090 be38c2e6ae5ede2dcf4756b193a0ec40 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 446 466 2.3E-48 T 28-03-2018 CFK41_RS06090 be38c2e6ae5ede2dcf4756b193a0ec40 481 PIRSF PIRSF000350 4 474 4.2E-71 T 28-03-2018 CFK41_RS06090 be38c2e6ae5ede2dcf4756b193a0ec40 481 Gene3D G3DSA:3.50.50.60 166 287 5.8E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS06090 be38c2e6ae5ede2dcf4756b193a0ec40 481 SUPERFAMILY SSF51905 87 352 9.48E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS06090 be38c2e6ae5ede2dcf4756b193a0ec40 481 SUPERFAMILY SSF51905 8 59 9.48E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS06090 be38c2e6ae5ede2dcf4756b193a0ec40 481 SUPERFAMILY SSF55424 363 473 2.75E-25 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CFK41_RS06090 be38c2e6ae5ede2dcf4756b193a0ec40 481 Gene3D G3DSA:3.50.50.60 12 165 2.1E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS06090 be38c2e6ae5ede2dcf4756b193a0ec40 481 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 16 343 1.5E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS00435 e98e5054d1ffe5d16753affb6276f90c 423 SUPERFAMILY SSF51735 11 238 1.12E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS00435 e98e5054d1ffe5d16753affb6276f90c 423 SUPERFAMILY SSF48179 239 419 5.44E-36 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CFK41_RS00435 e98e5054d1ffe5d16753affb6276f90c 423 Gene3D G3DSA:3.40.50.720 4 237 1.2E-73 T 28-03-2018 CFK41_RS00435 e98e5054d1ffe5d16753affb6276f90c 423 Gene3D G3DSA:1.10.1040.10 242 421 4.7E-39 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CFK41_RS00435 e98e5054d1ffe5d16753affb6276f90c 423 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 173 400 1.1E-57 T 28-03-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 CFK41_RS00435 e98e5054d1ffe5d16753affb6276f90c 423 PRINTS PR00084 Mannitol dehydrogenase signature 138 151 1.9E-14 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CFK41_RS00435 e98e5054d1ffe5d16753affb6276f90c 423 PRINTS PR00084 Mannitol dehydrogenase signature 174 187 1.9E-14 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CFK41_RS00435 e98e5054d1ffe5d16753affb6276f90c 423 PRINTS PR00084 Mannitol dehydrogenase signature 204 219 1.9E-14 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CFK41_RS00435 e98e5054d1ffe5d16753affb6276f90c 423 PRINTS PR00084 Mannitol dehydrogenase signature 12 22 1.9E-14 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CFK41_RS00435 e98e5054d1ffe5d16753affb6276f90c 423 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 11 147 3.3E-17 T 28-03-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 CFK41_RS04395 0e0bb46fc65347cd3567a27b9e17126d 325 SUPERFAMILY SSF51604 78 292 6.16E-50 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS04395 0e0bb46fc65347cd3567a27b9e17126d 325 Pfam PF13378 Enolase C-terminal domain-like 99 292 3.4E-35 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS04395 0e0bb46fc65347cd3567a27b9e17126d 325 Gene3D G3DSA:3.30.390.10 14 94 4.9E-35 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS04395 0e0bb46fc65347cd3567a27b9e17126d 325 Gene3D G3DSA:3.20.20.120 95 279 7.1E-42 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS04395 0e0bb46fc65347cd3567a27b9e17126d 325 SMART SM00922 87 187 1.3E-19 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CFK41_RS04395 0e0bb46fc65347cd3567a27b9e17126d 325 Hamap MF_00470 o-succinylbenzoate synthase [menC]. 9 293 22.321 T 28-03-2018 IPR010196 o-Succinylbenzoate synthase, MenC type1 GO:0000287|GO:0009234|GO:0016836 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS13095 20b81530272aca27d5352dd7a4534faf 152 SUPERFAMILY SSF55961 1 107 6.6E-18 T 28-03-2018 CFK41_RS13095 20b81530272aca27d5352dd7a4534faf 152 Gene3D G3DSA:3.30.530.20 1 152 2.1E-23 T 28-03-2018 IPR023393 START-like domain CFK41_RS13095 20b81530272aca27d5352dd7a4534faf 152 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 107 2.4E-13 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CFK41_RS15350 f303fed94a729d311bc0055128cbd34a 381 Gene3D G3DSA:3.40.640.10 13 246 8.9E-51 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS15350 f303fed94a729d311bc0055128cbd34a 381 Gene3D G3DSA:3.90.1150.10 247 365 1.7E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS15350 f303fed94a729d311bc0055128cbd34a 381 SUPERFAMILY SSF53383 1 374 9.84E-91 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS15350 f303fed94a729d311bc0055128cbd34a 381 PIRSF PIRSF005572 1 380 1.9E-104 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CFK41_RS15350 f303fed94a729d311bc0055128cbd34a 381 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 189 208 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CFK41_RS15350 f303fed94a729d311bc0055128cbd34a 381 Pfam PF00266 Aminotransferase class-V 3 340 1.5E-61 T 28-03-2018 IPR000192 Aminotransferase class V domain CFK41_RS00945 d3eef1bc356e3e8af24f99520e305174 431 Gene3D G3DSA:1.10.540.10 49 165 4.6E-18 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CFK41_RS00945 d3eef1bc356e3e8af24f99520e305174 431 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 167 265 2.2E-20 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CFK41_RS00945 d3eef1bc356e3e8af24f99520e305174 431 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 383 402 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CFK41_RS00945 d3eef1bc356e3e8af24f99520e305174 431 Gene3D G3DSA:1.20.140.10 266 429 8.3E-37 T 28-03-2018 CFK41_RS00945 d3eef1bc356e3e8af24f99520e305174 431 SUPERFAMILY SSF56645 64 275 1.44E-52 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CFK41_RS00945 d3eef1bc356e3e8af24f99520e305174 431 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 284 424 3.5E-30 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CFK41_RS00945 d3eef1bc356e3e8af24f99520e305174 431 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 63 162 1.4E-14 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CFK41_RS00945 d3eef1bc356e3e8af24f99520e305174 431 SUPERFAMILY SSF47203 279 427 4.19E-38 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CFK41_RS00945 d3eef1bc356e3e8af24f99520e305174 431 Gene3D G3DSA:2.40.110.10 166 265 2.7E-27 T 28-03-2018 CFK41_RS06165 460f292e9bbd3e305e50a8dc0a8810c9 1158 Gene3D G3DSA:3.40.50.2000 1028 1148 2.2E-6 T 28-03-2018 CFK41_RS06165 460f292e9bbd3e305e50a8dc0a8810c9 1158 Gene3D G3DSA:3.40.50.2000 201 369 2.3E-32 T 28-03-2018 CFK41_RS06165 460f292e9bbd3e305e50a8dc0a8810c9 1158 Pfam PF00534 Glycosyl transferases group 1 214 363 2.5E-26 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CFK41_RS06165 460f292e9bbd3e305e50a8dc0a8810c9 1158 SUPERFAMILY SSF53756 2 380 2.42E-44 T 28-03-2018 CFK41_RS06165 460f292e9bbd3e305e50a8dc0a8810c9 1158 SUPERFAMILY SSF53756 1029 1134 4.49E-7 T 28-03-2018 CFK41_RS03915 6f4c887920bc3fab6e0dfc3f748748f1 257 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 183 5.9E-6 T 28-03-2018 CFK41_RS03915 6f4c887920bc3fab6e0dfc3f748748f1 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 9.9E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03915 6f4c887920bc3fab6e0dfc3f748748f1 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 9.9E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03915 6f4c887920bc3fab6e0dfc3f748748f1 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 9.9E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03915 6f4c887920bc3fab6e0dfc3f748748f1 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 9.9E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03915 6f4c887920bc3fab6e0dfc3f748748f1 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 9.9E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03915 6f4c887920bc3fab6e0dfc3f748748f1 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 9.9E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03915 6f4c887920bc3fab6e0dfc3f748748f1 257 Gene3D G3DSA:3.40.50.720 48 253 7.5E-69 T 28-03-2018 CFK41_RS03915 6f4c887920bc3fab6e0dfc3f748748f1 257 Gene3D G3DSA:3.40.50.720 1 47 5.0E-10 T 28-03-2018 CFK41_RS03915 6f4c887920bc3fab6e0dfc3f748748f1 257 SUPERFAMILY SSF51735 1 246 2.86E-83 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS03915 6f4c887920bc3fab6e0dfc3f748748f1 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 243 1.5E-65 T 28-03-2018 CFK41_RS03915 6f4c887920bc3fab6e0dfc3f748748f1 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 3.7E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03915 6f4c887920bc3fab6e0dfc3f748748f1 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 3.7E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03915 6f4c887920bc3fab6e0dfc3f748748f1 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 3.7E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03915 6f4c887920bc3fab6e0dfc3f748748f1 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CFK41_RS06510 fd74ab754759520c85df0151dc788381 168 Gene3D G3DSA:2.40.280.10 22 140 4.4E-46 T 28-03-2018 IPR023620 Small protein B CFK41_RS06510 fd74ab754759520c85df0151dc788381 168 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 22 145 1.0E-40 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CFK41_RS06510 fd74ab754759520c85df0151dc788381 168 SUPERFAMILY SSF74982 17 145 4.19E-48 T 28-03-2018 IPR023620 Small protein B CFK41_RS06510 fd74ab754759520c85df0151dc788381 168 Pfam PF01668 SmpB protein 22 164 2.6E-56 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CFK41_RS06510 fd74ab754759520c85df0151dc788381 168 Hamap MF_00023 SsrA-binding protein [smpB]. 1 168 61.159 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CFK41_RS06510 fd74ab754759520c85df0151dc788381 168 TIGRFAM TIGR00086 smpB: SsrA-binding protein 22 163 2.5E-53 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CFK41_RS06510 fd74ab754759520c85df0151dc788381 168 ProSitePatterns PS01317 SsrA-binding protein. 40 52 - T 28-03-2018 IPR020081 SsrA-binding protein, conserved site CFK41_RS13260 87024cbc694902b004bbca980d3a7cdb 372 PRINTS PR01217 Proline rich extensin signature 122 143 1.8E-9 T 28-03-2018 CFK41_RS13260 87024cbc694902b004bbca980d3a7cdb 372 PRINTS PR01217 Proline rich extensin signature 145 161 1.8E-9 T 28-03-2018 CFK41_RS13260 87024cbc694902b004bbca980d3a7cdb 372 PRINTS PR01217 Proline rich extensin signature 101 113 1.8E-9 T 28-03-2018 CFK41_RS13260 87024cbc694902b004bbca980d3a7cdb 372 PRINTS PR01217 Proline rich extensin signature 170 187 1.8E-9 T 28-03-2018 CFK41_RS13260 87024cbc694902b004bbca980d3a7cdb 372 PRINTS PR01217 Proline rich extensin signature 189 214 1.8E-9 T 28-03-2018 CFK41_RS15565 1d25381f9f78736b2fffdfa4882b1dd4 354 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS15565 1d25381f9f78736b2fffdfa4882b1dd4 354 Pfam PF00005 ABC transporter 41 187 6.7E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS15565 1d25381f9f78736b2fffdfa4882b1dd4 354 Gene3D G3DSA:3.40.50.300 14 260 4.9E-69 T 28-03-2018 CFK41_RS15565 1d25381f9f78736b2fffdfa4882b1dd4 354 SUPERFAMILY SSF52540 17 254 7.73E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS15565 1d25381f9f78736b2fffdfa4882b1dd4 354 SMART SM00382 48 236 4.7E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS15565 1d25381f9f78736b2fffdfa4882b1dd4 354 Gene3D G3DSA:3.30.70.260 261 354 8.5E-11 T 28-03-2018 CFK41_RS08960 eb3209aecef08a0e6fa9afffcb61584e 333 Pfam PF01261 Xylose isomerase-like TIM barrel 22 273 3.8E-39 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS08960 eb3209aecef08a0e6fa9afffcb61584e 333 SUPERFAMILY SSF51658 4 316 3.4E-58 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS08960 eb3209aecef08a0e6fa9afffcb61584e 333 Pfam PF07582 AP endonuclease family 2 C terminus 274 328 5.7E-22 T 28-03-2018 IPR011418 AP endonuclease, family 2, C-terminal CFK41_RS08960 eb3209aecef08a0e6fa9afffcb61584e 333 Gene3D G3DSA:3.20.20.150 1 318 2.2E-59 T 28-03-2018 CFK41_RS01165 105fb3fb4d823baa74dcc2fb5c8605b8 310 Gene3D G3DSA:1.10.3720.10 32 297 3.8E-36 T 28-03-2018 CFK41_RS01165 105fb3fb4d823baa74dcc2fb5c8605b8 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 303 7.3E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01165 105fb3fb4d823baa74dcc2fb5c8605b8 310 SUPERFAMILY SSF161098 41 309 2.15E-62 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS10120 309be1ba0921c185aea027dfd63773b3 281 Gene3D G3DSA:3.40.50.150 65 280 5.9E-51 T 28-03-2018 CFK41_RS10120 309be1ba0921c185aea027dfd63773b3 281 SUPERFAMILY SSF53335 62 190 1.28E-17 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS10120 309be1ba0921c185aea027dfd63773b3 281 Pfam PF01728 FtsJ-like methyltransferase 63 241 6.8E-17 T 28-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 CFK41_RS10120 309be1ba0921c185aea027dfd63773b3 281 SUPERFAMILY SSF55174 5 55 5.3E-11 T 28-03-2018 CFK41_RS10120 309be1ba0921c185aea027dfd63773b3 281 Gene3D G3DSA:3.10.290.10 3 64 2.3E-14 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CFK41_RS10120 309be1ba0921c185aea027dfd63773b3 281 SMART SM00363 4 68 2.9E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CFK41_RS10120 309be1ba0921c185aea027dfd63773b3 281 PIRSF PIRSF005578 1 263 7.6E-81 T 28-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 CFK41_RS10120 309be1ba0921c185aea027dfd63773b3 281 Pfam PF01479 S4 domain 5 48 2.4E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CFK41_RS04280 9c0770a41f1e9334c4c7c922479b199c 288 PIRSF PIRSF000193 24 288 2.9E-68 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CFK41_RS04280 9c0770a41f1e9334c4c7c922479b199c 288 Gene3D G3DSA:3.40.50.720 21 183 2.2E-31 T 28-03-2018 CFK41_RS04280 9c0770a41f1e9334c4c7c922479b199c 288 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 25 118 4.7E-18 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CFK41_RS04280 9c0770a41f1e9334c4c7c922479b199c 288 SUPERFAMILY SSF51735 25 177 4.85E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS04280 9c0770a41f1e9334c4c7c922479b199c 288 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 181 285 9.2E-28 T 28-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CFK41_RS04280 9c0770a41f1e9334c4c7c922479b199c 288 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 24 285 23.621 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CFK41_RS04280 9c0770a41f1e9334c4c7c922479b199c 288 SUPERFAMILY SSF48179 181 286 7.99E-27 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CFK41_RS04280 9c0770a41f1e9334c4c7c922479b199c 288 Gene3D G3DSA:1.10.3730.10 184 288 7.4E-33 T 28-03-2018 CFK41_RS04280 9c0770a41f1e9334c4c7c922479b199c 288 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 26 285 9.5E-69 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CFK41_RS03240 e1160ce47b0da37e75234e37ef04faec 483 Pfam PF07690 Major Facilitator Superfamily 34 431 4.6E-26 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS03240 e1160ce47b0da37e75234e37ef04faec 483 Gene3D G3DSA:1.20.1250.20 281 483 1.1E-7 T 28-03-2018 CFK41_RS03240 e1160ce47b0da37e75234e37ef04faec 483 Gene3D G3DSA:1.20.1250.20 18 212 1.5E-22 T 28-03-2018 CFK41_RS03240 e1160ce47b0da37e75234e37ef04faec 483 SUPERFAMILY SSF103473 30 221 1.4E-35 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS03240 e1160ce47b0da37e75234e37ef04faec 483 SUPERFAMILY SSF103473 270 476 1.4E-35 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS04065 16e9d492f5f3ec0f53def30cec387c63 302 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 40 299 4.3E-47 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CFK41_RS04065 16e9d492f5f3ec0f53def30cec387c63 302 Gene3D G3DSA:3.40.190.10 30 181 3.1E-31 T 28-03-2018 CFK41_RS04065 16e9d492f5f3ec0f53def30cec387c63 302 Gene3D G3DSA:3.40.190.10 183 302 4.7E-14 T 28-03-2018 CFK41_RS04065 16e9d492f5f3ec0f53def30cec387c63 302 SUPERFAMILY SSF53850 41 300 5.43E-47 T 28-03-2018 CFK41_RS01295 dac21e1505938a9e25c1277375b9d9a4 312 Gene3D G3DSA:1.20.58.370 6 60 2.0E-6 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CFK41_RS01295 dac21e1505938a9e25c1277375b9d9a4 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 303 6.7E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01295 dac21e1505938a9e25c1277375b9d9a4 312 SUPERFAMILY SSF161098 70 298 6.93E-53 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01295 dac21e1505938a9e25c1277375b9d9a4 312 Gene3D G3DSA:1.10.3720.10 78 308 9.9E-42 T 28-03-2018 CFK41_RS12660 ae1524c81f6107541b184d1b7794943f 87 Gene3D G3DSA:3.10.20.30 8 87 2.0E-17 T 28-03-2018 IPR012675 Beta-grasp domain CFK41_RS12660 ae1524c81f6107541b184d1b7794943f 87 Pfam PF02597 ThiS family 12 87 2.3E-7 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CFK41_RS12660 ae1524c81f6107541b184d1b7794943f 87 SUPERFAMILY SSF54285 10 87 1.07E-9 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CFK41_RS15795 0760cc0e8efeb4884f66e8456725e414 804 Gene3D G3DSA:3.20.20.210 36 424 4.7E-109 T 28-03-2018 CFK41_RS15795 0760cc0e8efeb4884f66e8456725e414 804 SUPERFAMILY SSF51726 442 796 2.75E-104 T 28-03-2018 CFK41_RS15795 0760cc0e8efeb4884f66e8456725e414 804 PIRSF PIRSF000382 36 801 5.2E-276 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CFK41_RS15795 0760cc0e8efeb4884f66e8456725e414 804 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 40 356 8.7E-87 T 28-03-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CFK41_RS15795 0760cc0e8efeb4884f66e8456725e414 804 SUPERFAMILY SSF51726 38 411 1.44E-76 T 28-03-2018 CFK41_RS15795 0760cc0e8efeb4884f66e8456725e414 804 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 470 792 1.2E-137 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CFK41_RS15795 0760cc0e8efeb4884f66e8456725e414 804 Gene3D G3DSA:3.20.20.210 429 798 3.7E-119 T 28-03-2018 CFK41_RS07565 abd3142b28d70b3ba8895e79ee5ed613 210 PIRSF PIRSF000709 4 114 2.0E-8 T 28-03-2018 CFK41_RS07565 abd3142b28d70b3ba8895e79ee5ed613 210 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 10 19 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CFK41_RS07565 abd3142b28d70b3ba8895e79ee5ed613 210 SMART SM00855 7 160 2.6E-23 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CFK41_RS07565 abd3142b28d70b3ba8895e79ee5ed613 210 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 8 191 4.3E-50 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CFK41_RS07565 abd3142b28d70b3ba8895e79ee5ed613 210 Gene3D G3DSA:3.40.50.1240 5 205 1.0E-45 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CFK41_RS07565 abd3142b28d70b3ba8895e79ee5ed613 210 SUPERFAMILY SSF53254 6 203 1.73E-49 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CFK41_RS10860 d3a0aacb73989c39a9e472de7b07cf37 225 SUPERFAMILY SSF51064 169 220 7.98E-17 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CFK41_RS10860 d3a0aacb73989c39a9e472de7b07cf37 225 Gene3D G3DSA:2.30.22.10 167 222 7.0E-22 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CFK41_RS10860 d3a0aacb73989c39a9e472de7b07cf37 225 Gene3D G3DSA:3.90.20.20 58 166 5.7E-10 T 28-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 CFK41_RS10860 d3a0aacb73989c39a9e472de7b07cf37 225 SUPERFAMILY SSF58014 81 167 5.1E-10 T 28-03-2018 CFK41_RS10860 d3a0aacb73989c39a9e472de7b07cf37 225 Hamap MF_01151 Protein GrpE [grpE]. 31 223 14.473 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CFK41_RS10860 d3a0aacb73989c39a9e472de7b07cf37 225 Pfam PF01025 GrpE 80 220 2.5E-31 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CFK41_RS10860 d3a0aacb73989c39a9e472de7b07cf37 225 PRINTS PR00773 GrpE protein signature 126 141 6.9E-17 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CFK41_RS10860 d3a0aacb73989c39a9e472de7b07cf37 225 PRINTS PR00773 GrpE protein signature 202 221 6.9E-17 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CFK41_RS10860 d3a0aacb73989c39a9e472de7b07cf37 225 PRINTS PR00773 GrpE protein signature 175 190 6.9E-17 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CFK41_RS10860 d3a0aacb73989c39a9e472de7b07cf37 225 PRINTS PR00773 GrpE protein signature 98 114 6.9E-17 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CFK41_RS05645 7913b80b4d1f90ad8eb0e6ca8116626a 207 SUPERFAMILY SSF54211 11 95 2.4E-32 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CFK41_RS05645 7913b80b4d1f90ad8eb0e6ca8116626a 207 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 11 207 40.146 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CFK41_RS05645 7913b80b4d1f90ad8eb0e6ca8116626a 207 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 169 181 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CFK41_RS05645 7913b80b4d1f90ad8eb0e6ca8116626a 207 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 40 187 5.2E-59 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CFK41_RS05645 7913b80b4d1f90ad8eb0e6ca8116626a 207 SUPERFAMILY SSF54211 96 191 3.41E-28 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CFK41_RS05645 7913b80b4d1f90ad8eb0e6ca8116626a 207 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 70 83 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CFK41_RS05645 7913b80b4d1f90ad8eb0e6ca8116626a 207 Gene3D G3DSA:3.30.230.40 99 207 2.0E-32 T 28-03-2018 CFK41_RS05645 7913b80b4d1f90ad8eb0e6ca8116626a 207 Gene3D G3DSA:3.30.230.40 8 97 1.7E-33 T 28-03-2018 CFK41_RS13505 1edce42d5c45b512b09aedcba864d339 166 Gene3D G3DSA:3.40.630.30 1 166 1.3E-19 T 28-03-2018 CFK41_RS13505 1edce42d5c45b512b09aedcba864d339 166 SUPERFAMILY SSF55729 2 150 6.62E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS13505 1edce42d5c45b512b09aedcba864d339 166 Pfam PF13302 Acetyltransferase (GNAT) domain 2 140 2.6E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS02075 cb2f4a963108478844e18ff183723855 189 Gene3D G3DSA:3.40.430.10 1 188 5.9E-34 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CFK41_RS02075 cb2f4a963108478844e18ff183723855 189 SUPERFAMILY SSF53597 2 188 2.36E-27 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CFK41_RS02075 cb2f4a963108478844e18ff183723855 189 Pfam PF01872 RibD C-terminal domain 4 180 1.1E-9 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CFK41_RS01065 11749716000d9c4211b610949e661b89 273 SUPERFAMILY SSF161098 67 252 1.57E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01065 11749716000d9c4211b610949e661b89 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 268 3.5E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01065 11749716000d9c4211b610949e661b89 273 Gene3D G3DSA:1.10.3720.10 59 269 3.8E-39 T 28-03-2018 CFK41_RS01065 11749716000d9c4211b610949e661b89 273 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 64 161 3.9E-22 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CFK41_RS14990 f9ac5f1a8ddefc791161b1574f440de8 266 Pfam PF02525 Flavodoxin-like fold 12 222 7.9E-44 T 28-03-2018 IPR003680 Flavodoxin-like fold CFK41_RS14990 f9ac5f1a8ddefc791161b1574f440de8 266 SUPERFAMILY SSF52218 13 244 2.0E-44 T 28-03-2018 IPR029039 Flavoprotein-like domain CFK41_RS14990 f9ac5f1a8ddefc791161b1574f440de8 266 Gene3D G3DSA:3.40.50.360 4 265 5.2E-42 T 28-03-2018 IPR029039 Flavoprotein-like domain CFK41_RS15925 6c9a40557a3c328249de89927617197f 583 Gene3D G3DSA:3.40.50.970 1 187 2.4E-40 T 28-03-2018 CFK41_RS15925 6c9a40557a3c328249de89927617197f 583 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 193 323 4.7E-27 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CFK41_RS15925 6c9a40557a3c328249de89927617197f 583 Gene3D G3DSA:3.40.50.1220 188 372 4.2E-33 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CFK41_RS15925 6c9a40557a3c328249de89927617197f 583 SUPERFAMILY SSF52467 183 348 6.55E-36 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CFK41_RS15925 6c9a40557a3c328249de89927617197f 583 Gene3D G3DSA:3.40.50.970 373 557 6.1E-35 T 28-03-2018 CFK41_RS15925 6c9a40557a3c328249de89927617197f 583 SUPERFAMILY SSF52518 1 173 3.34E-41 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CFK41_RS15925 6c9a40557a3c328249de89927617197f 583 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 6 171 1.4E-40 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CFK41_RS15925 6c9a40557a3c328249de89927617197f 583 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 387 533 1.3E-33 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CFK41_RS15925 6c9a40557a3c328249de89927617197f 583 SUPERFAMILY SSF52518 364 552 1.05E-54 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CFK41_RS15925 6c9a40557a3c328249de89927617197f 583 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 424 443 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CFK41_RS01490 0b7d9f3935046dca8eaea80349915d7e 288 SUPERFAMILY SSF161098 41 273 1.31E-41 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01490 0b7d9f3935046dca8eaea80349915d7e 288 Gene3D G3DSA:1.10.3720.10 1 286 7.9E-35 T 28-03-2018 CFK41_RS01490 0b7d9f3935046dca8eaea80349915d7e 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 281 7.0E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS00505 ec443f66efa122a2dc5cb2bd3398a31a 124 SUPERFAMILY SSF54593 1 120 3.09E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS00505 ec443f66efa122a2dc5cb2bd3398a31a 124 Gene3D G3DSA:3.10.180.10 1 121 3.5E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS00505 ec443f66efa122a2dc5cb2bd3398a31a 124 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 116 4.9E-7 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CFK41_RS10890 e5c826d754ba9764228d19e65bc9d2c1 95 Pfam PF09723 Zinc ribbon domain 1 40 1.1E-12 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CFK41_RS10890 e5c826d754ba9764228d19e65bc9d2c1 95 SMART SM00834 1 41 3.4E-11 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CFK41_RS10890 e5c826d754ba9764228d19e65bc9d2c1 95 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 46 4.1E-13 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CFK41_RS11610 6dbf6fc0944a3f562b603094fafe81a2 283 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 5 280 1.3E-60 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CFK41_RS11610 6dbf6fc0944a3f562b603094fafe81a2 283 SUPERFAMILY SSF54506 5 142 2.04E-30 T 28-03-2018 CFK41_RS11610 6dbf6fc0944a3f562b603094fafe81a2 283 Gene3D G3DSA:3.10.310.10 143 268 5.9E-36 T 28-03-2018 CFK41_RS11610 6dbf6fc0944a3f562b603094fafe81a2 283 SUPERFAMILY SSF54506 148 280 1.11E-27 T 28-03-2018 CFK41_RS11610 6dbf6fc0944a3f562b603094fafe81a2 283 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 5 283 28.674 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CFK41_RS11610 6dbf6fc0944a3f562b603094fafe81a2 283 Pfam PF01678 Diaminopimelate epimerase 160 275 4.8E-19 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CFK41_RS11610 6dbf6fc0944a3f562b603094fafe81a2 283 Pfam PF01678 Diaminopimelate epimerase 7 139 5.4E-30 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CFK41_RS11610 6dbf6fc0944a3f562b603094fafe81a2 283 Gene3D G3DSA:3.10.310.10 1 142 6.5E-45 T 28-03-2018 CFK41_RS11610 6dbf6fc0944a3f562b603094fafe81a2 283 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 75 89 - T 28-03-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CFK41_RS13910 192347cf84b2850a16f2ec2057f642d3 221 Pfam PF01730 UreF 56 175 5.6E-12 T 28-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 CFK41_RS00780 ea38d51773ea34fbcaf1cd29b79ddcf1 334 SUPERFAMILY SSF53807 47 316 3.92E-47 T 28-03-2018 CFK41_RS00780 ea38d51773ea34fbcaf1cd29b79ddcf1 334 Gene3D G3DSA:3.40.50.1980 32 164 7.2E-17 T 28-03-2018 CFK41_RS00780 ea38d51773ea34fbcaf1cd29b79ddcf1 334 Pfam PF01497 Periplasmic binding protein 64 309 8.6E-38 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CFK41_RS00780 ea38d51773ea34fbcaf1cd29b79ddcf1 334 Gene3D G3DSA:3.40.50.1980 165 334 6.7E-30 T 28-03-2018 CFK41_RS11730 1a27c5e16b54746c9ebf3e9e0b268223 316 Gene3D G3DSA:3.30.2350.10 4 225 3.0E-74 T 28-03-2018 CFK41_RS11730 1a27c5e16b54746c9ebf3e9e0b268223 316 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 181 214 3.7E-9 T 28-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 CFK41_RS11730 1a27c5e16b54746c9ebf3e9e0b268223 316 SUPERFAMILY SSF55120 5 220 4.89E-66 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CFK41_RS11730 1a27c5e16b54746c9ebf3e9e0b268223 316 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 6 216 7.9E-66 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CFK41_RS11730 1a27c5e16b54746c9ebf3e9e0b268223 316 Gene3D G3DSA:2.30.130.10 232 310 3.3E-13 T 28-03-2018 IPR002478 PUA domain GO:0003723 CFK41_RS11730 1a27c5e16b54746c9ebf3e9e0b268223 316 Pfam PF09142 tRNA Pseudouridine synthase II, C terminal 242 310 3.9E-7 T 28-03-2018 IPR015225 tRNA pseudouridine synthase II, TruB, subfamily 2, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CFK41_RS11730 1a27c5e16b54746c9ebf3e9e0b268223 316 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 5 310 16.857 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CFK41_RS11730 1a27c5e16b54746c9ebf3e9e0b268223 316 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 27 180 4.7E-48 T 28-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 CFK41_RS07385 238747428dfeaaa6da21626730b8b66b 371 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 3 364 38.925 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CFK41_RS07385 238747428dfeaaa6da21626730b8b66b 371 SUPERFAMILY SSF52440 1 144 3.26E-33 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CFK41_RS07385 238747428dfeaaa6da21626730b8b66b 371 Gene3D G3DSA:3.40.50.20 1 140 1.2E-40 T 28-03-2018 CFK41_RS07385 238747428dfeaaa6da21626730b8b66b 371 SUPERFAMILY SSF56059 145 364 2.95E-53 T 28-03-2018 CFK41_RS07385 238747428dfeaaa6da21626730b8b66b 371 Gene3D G3DSA:3.30.470.20 221 369 3.9E-38 T 28-03-2018 CFK41_RS07385 238747428dfeaaa6da21626730b8b66b 371 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 306 334 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CFK41_RS07385 238747428dfeaaa6da21626730b8b66b 371 PIRSF PIRSF039102 1 369 4.1E-106 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CFK41_RS07385 238747428dfeaaa6da21626730b8b66b 371 Gene3D G3DSA:3.30.1490.20 141 220 1.6E-18 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CFK41_RS07385 238747428dfeaaa6da21626730b8b66b 371 Pfam PF07478 D-ala D-ala ligase C-terminus 154 361 7.0E-62 T 28-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CFK41_RS07385 238747428dfeaaa6da21626730b8b66b 371 Pfam PF01820 D-ala D-ala ligase N-terminus 5 135 3.5E-28 T 28-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CFK41_RS07385 238747428dfeaaa6da21626730b8b66b 371 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 5 363 7.3E-96 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CFK41_RS07385 238747428dfeaaa6da21626730b8b66b 371 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 112 123 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CFK41_RS07250 10d32ddaf3e8e078423de7e6ca96f743 535 SMART SM00997 132 289 0.0087 T 28-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CFK41_RS07250 10d32ddaf3e8e078423de7e6ca96f743 535 SUPERFAMILY SSF55021 448 527 9.99E-10 T 28-03-2018 CFK41_RS07250 10d32ddaf3e8e078423de7e6ca96f743 535 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 6 533 1.3E-172 T 28-03-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 CFK41_RS07250 10d32ddaf3e8e078423de7e6ca96f743 535 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 285 2.6E-60 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CFK41_RS07250 10d32ddaf3e8e078423de7e6ca96f743 535 Gene3D G3DSA:3.40.50.720 113 288 8.7E-54 T 28-03-2018 CFK41_RS07250 10d32ddaf3e8e078423de7e6ca96f743 535 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 144 171 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CFK41_RS07250 10d32ddaf3e8e078423de7e6ca96f743 535 Gene3D G3DSA:3.30.70.260 454 531 2.3E-9 T 28-03-2018 CFK41_RS07250 10d32ddaf3e8e078423de7e6ca96f743 535 SUPERFAMILY SSF52283 3 135 1.02E-35 T 28-03-2018 CFK41_RS07250 10d32ddaf3e8e078423de7e6ca96f743 535 SUPERFAMILY SSF143548 324 453 7.32E-30 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CFK41_RS07250 10d32ddaf3e8e078423de7e6ca96f743 535 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 6 317 1.1E-31 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CFK41_RS07250 10d32ddaf3e8e078423de7e6ca96f743 535 Gene3D G3DSA:3.30.1330.90 319 453 1.2E-27 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CFK41_RS07250 10d32ddaf3e8e078423de7e6ca96f743 535 Gene3D G3DSA:3.40.50.720 3 112 2.7E-31 T 28-03-2018 CFK41_RS07250 10d32ddaf3e8e078423de7e6ca96f743 535 SUPERFAMILY SSF51735 101 285 1.24E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS10220 037d6e9a016abebd0a22f9c7a82fe866 326 SMART SM01400 12 128 5.8E-66 T 28-03-2018 CFK41_RS10220 037d6e9a016abebd0a22f9c7a82fe866 326 Gene3D G3DSA:3.40.50.2020 9 164 2.7E-60 T 28-03-2018 CFK41_RS10220 037d6e9a016abebd0a22f9c7a82fe866 326 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 12 323 44.077 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CFK41_RS10220 037d6e9a016abebd0a22f9c7a82fe866 326 SUPERFAMILY SSF53271 77 314 8.6E-59 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CFK41_RS10220 037d6e9a016abebd0a22f9c7a82fe866 326 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 136 151 - T 28-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 CFK41_RS10220 037d6e9a016abebd0a22f9c7a82fe866 326 Pfam PF14572 Phosphoribosyl synthetase-associated domain 216 322 5.4E-23 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CFK41_RS10220 037d6e9a016abebd0a22f9c7a82fe866 326 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 14 323 8.6E-112 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CFK41_RS10220 037d6e9a016abebd0a22f9c7a82fe866 326 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 13 128 5.4E-42 T 28-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CFK41_RS10220 037d6e9a016abebd0a22f9c7a82fe866 326 Gene3D G3DSA:3.40.50.2020 165 301 3.1E-38 T 28-03-2018 CFK41_RS03585 4680ef5e0c3d3d0aed902ace17545f9d 314 Pfam PF00293 NUDIX domain 13 124 1.7E-20 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CFK41_RS03585 4680ef5e0c3d3d0aed902ace17545f9d 314 Gene3D G3DSA:3.90.79.10 1 148 1.7E-34 T 28-03-2018 CFK41_RS03585 4680ef5e0c3d3d0aed902ace17545f9d 314 Gene3D G3DSA:3.40.50.1240 150 312 3.7E-19 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CFK41_RS03585 4680ef5e0c3d3d0aed902ace17545f9d 314 SMART SM00855 150 264 2.3E-6 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CFK41_RS03585 4680ef5e0c3d3d0aed902ace17545f9d 314 PRINTS PR00502 NUDIX hydrolase family signature 39 53 1.7E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CFK41_RS03585 4680ef5e0c3d3d0aed902ace17545f9d 314 PRINTS PR00502 NUDIX hydrolase family signature 53 68 1.7E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CFK41_RS03585 4680ef5e0c3d3d0aed902ace17545f9d 314 SUPERFAMILY SSF53254 151 265 5.57E-14 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CFK41_RS03585 4680ef5e0c3d3d0aed902ace17545f9d 314 SUPERFAMILY SSF55811 6 140 2.3E-30 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CFK41_RS03585 4680ef5e0c3d3d0aed902ace17545f9d 314 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 151 229 1.6E-10 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CFK41_RS03585 4680ef5e0c3d3d0aed902ace17545f9d 314 ProSitePatterns PS00893 Nudix box signature. 44 65 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CFK41_RS02065 8593dc85c85822cd98c88a6b0bf8629b 300 Gene3D G3DSA:2.60.120.280 29 178 4.6E-14 T 28-03-2018 CFK41_RS02065 8593dc85c85822cd98c88a6b0bf8629b 300 Pfam PF02311 AraC-like ligand binding domain 45 96 5.9E-11 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CFK41_RS02065 8593dc85c85822cd98c88a6b0bf8629b 300 SMART SM00342 209 292 3.8E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CFK41_RS02065 8593dc85c85822cd98c88a6b0bf8629b 300 Gene3D G3DSA:1.10.10.60 249 295 7.4E-10 T 28-03-2018 CFK41_RS02065 8593dc85c85822cd98c88a6b0bf8629b 300 SUPERFAMILY SSF46689 195 240 3.76E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS02065 8593dc85c85822cd98c88a6b0bf8629b 300 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 246 288 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CFK41_RS02065 8593dc85c85822cd98c88a6b0bf8629b 300 SUPERFAMILY SSF46689 245 294 4.93E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS02065 8593dc85c85822cd98c88a6b0bf8629b 300 SUPERFAMILY SSF51215 33 97 5.23E-13 T 28-03-2018 CFK41_RS02065 8593dc85c85822cd98c88a6b0bf8629b 300 Pfam PF12833 Helix-turn-helix domain 216 293 3.8E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CFK41_RS02065 8593dc85c85822cd98c88a6b0bf8629b 300 Gene3D G3DSA:1.10.10.60 189 248 3.8E-11 T 28-03-2018 CFK41_RS05895 29ae8b5d57ef172d1eb93e1b93c94f5d 1488 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 110 196 1.1E-15 T 28-03-2018 IPR032030 YscD, cytoplasmic domain CFK41_RS05895 29ae8b5d57ef172d1eb93e1b93c94f5d 1488 SUPERFAMILY SSF52540 665 877 2.31E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS05895 29ae8b5d57ef172d1eb93e1b93c94f5d 1488 Gene3D G3DSA:3.40.50.300 1225 1427 5.0E-6 T 28-03-2018 CFK41_RS05895 29ae8b5d57ef172d1eb93e1b93c94f5d 1488 SUPERFAMILY SSF49879 101 197 2.3E-19 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 CFK41_RS05895 29ae8b5d57ef172d1eb93e1b93c94f5d 1488 SMART SM00382 1021 1197 0.096 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS05895 29ae8b5d57ef172d1eb93e1b93c94f5d 1488 SMART SM00382 1299 1486 1.0 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS05895 29ae8b5d57ef172d1eb93e1b93c94f5d 1488 SMART SM00382 696 869 0.52 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS05895 29ae8b5d57ef172d1eb93e1b93c94f5d 1488 Pfam PF01580 FtsK/SpoIIIE family 669 876 1.5E-28 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CFK41_RS05895 29ae8b5d57ef172d1eb93e1b93c94f5d 1488 Pfam PF01580 FtsK/SpoIIIE family 1013 1200 2.0E-23 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CFK41_RS05895 29ae8b5d57ef172d1eb93e1b93c94f5d 1488 Gene3D G3DSA:3.40.50.300 630 883 2.1E-22 T 28-03-2018 CFK41_RS05895 29ae8b5d57ef172d1eb93e1b93c94f5d 1488 Gene3D G3DSA:3.40.50.300 993 1210 7.6E-14 T 28-03-2018 CFK41_RS05895 29ae8b5d57ef172d1eb93e1b93c94f5d 1488 SUPERFAMILY SSF52540 1299 1414 5.25E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS05895 29ae8b5d57ef172d1eb93e1b93c94f5d 1488 Gene3D G3DSA:2.60.200.20 103 210 2.0E-18 T 28-03-2018 CFK41_RS05895 29ae8b5d57ef172d1eb93e1b93c94f5d 1488 SUPERFAMILY SSF52540 1022 1200 5.43E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS06560 ceb983114ea3ba45eca2b6b3246d906b 551 Gene3D G3DSA:3.10.105.10 292 507 4.5E-37 T 28-03-2018 CFK41_RS06560 ceb983114ea3ba45eca2b6b3246d906b 551 PIRSF PIRSF002741 4 515 7.3E-59 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CFK41_RS06560 ceb983114ea3ba45eca2b6b3246d906b 551 Gene3D G3DSA:3.90.76.10 69 160 1.3E-18 T 28-03-2018 CFK41_RS06560 ceb983114ea3ba45eca2b6b3246d906b 551 Gene3D G3DSA:3.40.190.10 161 291 1.6E-22 T 28-03-2018 CFK41_RS06560 ceb983114ea3ba45eca2b6b3246d906b 551 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 83 433 5.7E-63 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CFK41_RS06560 ceb983114ea3ba45eca2b6b3246d906b 551 SUPERFAMILY SSF53850 52 522 5.43E-87 T 28-03-2018 CFK41_RS02905 23a9efb3b2acd570832f65cd5d249313 258 Pfam PF00106 short chain dehydrogenase 4 187 4.8E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02905 23a9efb3b2acd570832f65cd5d249313 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 7.0E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02905 23a9efb3b2acd570832f65cd5d249313 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 7.0E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02905 23a9efb3b2acd570832f65cd5d249313 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 7.0E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02905 23a9efb3b2acd570832f65cd5d249313 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 7.0E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02905 23a9efb3b2acd570832f65cd5d249313 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 7.0E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02905 23a9efb3b2acd570832f65cd5d249313 258 SUPERFAMILY SSF51735 3 247 1.23E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS02905 23a9efb3b2acd570832f65cd5d249313 258 Gene3D G3DSA:3.40.50.720 4 242 2.3E-44 T 28-03-2018 CFK41_RS02905 23a9efb3b2acd570832f65cd5d249313 258 PIRSF PIRSF000126 1 258 7.2E-58 T 28-03-2018 CFK41_RS02905 23a9efb3b2acd570832f65cd5d249313 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 4.0E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02905 23a9efb3b2acd570832f65cd5d249313 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 4.0E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02905 23a9efb3b2acd570832f65cd5d249313 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 4.0E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS04210 45c14391ebf0d46efb034c0616f87373 443 SUPERFAMILY SSF54631 273 387 1.12E-12 T 28-03-2018 CFK41_RS04210 45c14391ebf0d46efb034c0616f87373 443 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 37 388 6.5E-116 T 28-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 CFK41_RS04210 45c14391ebf0d46efb034c0616f87373 443 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS04210 45c14391ebf0d46efb034c0616f87373 443 Gene3D G3DSA:3.10.580.10 269 389 9.0E-11 T 28-03-2018 CFK41_RS04210 45c14391ebf0d46efb034c0616f87373 443 SUPERFAMILY SSF52540 42 269 6.82E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS04210 45c14391ebf0d46efb034c0616f87373 443 SMART SM00382 52 249 5.7E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS04210 45c14391ebf0d46efb034c0616f87373 443 Pfam PF00005 ABC transporter 45 191 5.9E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS04210 45c14391ebf0d46efb034c0616f87373 443 Gene3D G3DSA:3.40.50.300 1 268 6.8E-71 T 28-03-2018 CFK41_RS09540 69cfa9b5b3c54c1d984dc790879e67c2 320 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 48 55 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CFK41_RS09540 69cfa9b5b3c54c1d984dc790879e67c2 320 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 48 67 4.1E-19 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CFK41_RS09540 69cfa9b5b3c54c1d984dc790879e67c2 320 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 134 145 4.1E-19 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CFK41_RS09540 69cfa9b5b3c54c1d984dc790879e67c2 320 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 274 297 4.1E-19 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CFK41_RS09540 69cfa9b5b3c54c1d984dc790879e67c2 320 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 262 271 4.1E-19 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CFK41_RS09540 69cfa9b5b3c54c1d984dc790879e67c2 320 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 2 309 4.5E-88 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CFK41_RS09540 69cfa9b5b3c54c1d984dc790879e67c2 320 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 159 307 1.8E-18 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CFK41_RS09540 69cfa9b5b3c54c1d984dc790879e67c2 320 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 146 4.0E-43 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CFK41_RS09540 69cfa9b5b3c54c1d984dc790879e67c2 320 SUPERFAMILY SSF53671 1 309 3.67E-88 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CFK41_RS09540 69cfa9b5b3c54c1d984dc790879e67c2 320 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 311 39.514 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CFK41_RS09540 69cfa9b5b3c54c1d984dc790879e67c2 320 Gene3D G3DSA:3.40.50.1370 1 166 1.7E-60 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CFK41_RS09540 69cfa9b5b3c54c1d984dc790879e67c2 320 Gene3D G3DSA:3.40.50.1370 167 311 5.9E-40 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CFK41_RS09540 69cfa9b5b3c54c1d984dc790879e67c2 320 PRINTS PR00101 Aspartate carbamoyltransferase signature 133 150 3.2E-29 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CFK41_RS09540 69cfa9b5b3c54c1d984dc790879e67c2 320 PRINTS PR00101 Aspartate carbamoyltransferase signature 266 271 3.2E-29 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CFK41_RS09540 69cfa9b5b3c54c1d984dc790879e67c2 320 PRINTS PR00101 Aspartate carbamoyltransferase signature 38 60 3.2E-29 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CFK41_RS09540 69cfa9b5b3c54c1d984dc790879e67c2 320 PRINTS PR00101 Aspartate carbamoyltransferase signature 224 233 3.2E-29 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CFK41_RS09540 69cfa9b5b3c54c1d984dc790879e67c2 320 PRINTS PR00101 Aspartate carbamoyltransferase signature 290 304 3.2E-29 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CFK41_RS09540 69cfa9b5b3c54c1d984dc790879e67c2 320 PRINTS PR00101 Aspartate carbamoyltransferase signature 76 85 3.2E-29 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CFK41_RS11940 b262d160b89dbb186166832f5f4f7683 533 SUPERFAMILY SSF52540 42 357 1.57E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11940 b262d160b89dbb186166832f5f4f7683 533 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 271 284 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CFK41_RS11940 b262d160b89dbb186166832f5f4f7683 533 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 8.4E-22 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CFK41_RS11940 b262d160b89dbb186166832f5f4f7683 533 SUPERFAMILY SSF47446 330 432 5.4E-35 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CFK41_RS11940 b262d160b89dbb186166832f5f4f7683 533 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 429 1.1E-173 T 28-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 CFK41_RS11940 b262d160b89dbb186166832f5f4f7683 533 SMART SM00963 1 86 6.8E-34 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CFK41_RS11940 b262d160b89dbb186166832f5f4f7683 533 Gene3D G3DSA:1.20.120.140 1 91 4.1E-27 T 28-03-2018 CFK41_RS11940 b262d160b89dbb186166832f5f4f7683 533 SMART SM00962 100 298 2.4E-102 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CFK41_RS11940 b262d160b89dbb186166832f5f4f7683 533 Gene3D G3DSA:3.40.50.300 93 299 1.9E-38 T 28-03-2018 CFK41_RS11940 b262d160b89dbb186166832f5f4f7683 533 SMART SM00382 99 303 3.4E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS11940 b262d160b89dbb186166832f5f4f7683 533 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 444 33.503 T 28-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 CFK41_RS11940 b262d160b89dbb186166832f5f4f7683 533 Pfam PF00448 SRP54-type protein, GTPase domain 100 297 3.7E-68 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CFK41_RS11940 b262d160b89dbb186166832f5f4f7683 533 Gene3D G3DSA:1.10.260.30 330 433 2.0E-36 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CFK41_RS11940 b262d160b89dbb186166832f5f4f7683 533 Pfam PF02978 Signal peptide binding domain 331 428 2.7E-32 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CFK41_RS14830 a2f1c5733cf4f0cfe840d902d73d9306 349 Gene3D G3DSA:3.20.20.100 9 326 9.9E-94 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS14830 a2f1c5733cf4f0cfe840d902d73d9306 349 Pfam PF00248 Aldo/keto reductase family 22 323 8.2E-75 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS14830 a2f1c5733cf4f0cfe840d902d73d9306 349 SUPERFAMILY SSF51430 9 325 3.4E-99 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS11885 98a6ea342b42a152ab3f7628475275f4 263 Pfam PF00717 Peptidase S24-like 74 116 6.0E-10 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CFK41_RS11885 98a6ea342b42a152ab3f7628475275f4 263 SUPERFAMILY SSF51306 67 114 4.55E-42 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CFK41_RS11885 98a6ea342b42a152ab3f7628475275f4 263 SUPERFAMILY SSF51306 144 249 4.55E-42 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CFK41_RS11885 98a6ea342b42a152ab3f7628475275f4 263 ProSitePatterns PS00501 Signal peptidases I serine active site. 77 84 - T 28-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CFK41_RS11885 98a6ea342b42a152ab3f7628475275f4 263 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 53 243 1.0E-38 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CFK41_RS11885 98a6ea342b42a152ab3f7628475275f4 263 Gene3D G3DSA:2.10.109.10 64 255 2.1E-43 T 28-03-2018 CFK41_RS11885 98a6ea342b42a152ab3f7628475275f4 263 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 197 216 3.0E-20 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CFK41_RS11885 98a6ea342b42a152ab3f7628475275f4 263 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 68 84 3.0E-20 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CFK41_RS11885 98a6ea342b42a152ab3f7628475275f4 263 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 149 161 3.0E-20 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CFK41_RS11885 98a6ea342b42a152ab3f7628475275f4 263 ProSitePatterns PS00761 Signal peptidases I signature 3. 202 215 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CFK41_RS11885 98a6ea342b42a152ab3f7628475275f4 263 Pfam PF10502 Signal peptidase, peptidase S26 133 239 1.4E-4 T 28-03-2018 IPR019533 Peptidase S26 CFK41_RS02150 d0b5d28976bcbfa975dd3c2b9b7e27cb 84 Gene3D G3DSA:3.40.1620.10 9 54 4.9E-7 T 28-03-2018 CFK41_RS02150 d0b5d28976bcbfa975dd3c2b9b7e27cb 84 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 13 52 2.5E-6 T 28-03-2018 CFK41_RS13070 e226c84e6141d1cae5b003097696a7b5 264 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 25 252 5.1E-13 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS13070 e226c84e6141d1cae5b003097696a7b5 264 Gene3D G3DSA:3.60.10.10 1 264 2.1E-33 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS13070 e226c84e6141d1cae5b003097696a7b5 264 SUPERFAMILY SSF56219 2 257 3.14E-35 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS07935 06ba0feb4cc2dabd925cd6ab13ae098c 1131 Gene3D G3DSA:2.60.120.430 579 755 9.8E-19 T 28-03-2018 CFK41_RS07935 06ba0feb4cc2dabd925cd6ab13ae098c 1131 Gene3D G3DSA:3.60.21.10 762 1042 2.3E-24 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CFK41_RS07935 06ba0feb4cc2dabd925cd6ab13ae098c 1131 Gene3D G3DSA:2.60.40.1080 503 578 5.0E-4 T 28-03-2018 CFK41_RS07935 06ba0feb4cc2dabd925cd6ab13ae098c 1131 Gene3D G3DSA:2.60.40.1080 1043 1130 2.8E-10 T 28-03-2018 CFK41_RS07935 06ba0feb4cc2dabd925cd6ab13ae098c 1131 SUPERFAMILY SSF56300 774 986 6.01E-24 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CFK41_RS07935 06ba0feb4cc2dabd925cd6ab13ae098c 1131 Pfam PF09992 Phosphodiester glycosidase 268 408 5.5E-26 T 28-03-2018 IPR018711 Phosphodiester glycosidase CFK41_RS07935 06ba0feb4cc2dabd925cd6ab13ae098c 1131 Pfam PF00149 Calcineurin-like phosphoesterase 774 963 6.4E-11 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CFK41_RS12615 a3a4fc06ffa18ce2a27c6dadc7ab6b80 528 SUPERFAMILY SSF52029 184 374 1.57E-77 T 28-03-2018 IPR027409 GroEL-like apical domain CFK41_RS12615 a3a4fc06ffa18ce2a27c6dadc7ab6b80 528 SUPERFAMILY SSF48592 1 226 1.26E-61 T 28-03-2018 CFK41_RS12615 a3a4fc06ffa18ce2a27c6dadc7ab6b80 528 PRINTS PR00298 60kDa chaperonin signature 26 52 3.5E-70 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CFK41_RS12615 a3a4fc06ffa18ce2a27c6dadc7ab6b80 528 PRINTS PR00298 60kDa chaperonin signature 348 373 3.5E-70 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CFK41_RS12615 a3a4fc06ffa18ce2a27c6dadc7ab6b80 528 PRINTS PR00298 60kDa chaperonin signature 266 289 3.5E-70 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CFK41_RS12615 a3a4fc06ffa18ce2a27c6dadc7ab6b80 528 PRINTS PR00298 60kDa chaperonin signature 82 109 3.5E-70 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CFK41_RS12615 a3a4fc06ffa18ce2a27c6dadc7ab6b80 528 PRINTS PR00298 60kDa chaperonin signature 396 417 3.5E-70 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CFK41_RS12615 a3a4fc06ffa18ce2a27c6dadc7ab6b80 528 Gene3D G3DSA:1.10.560.10 372 514 5.0E-24 T 28-03-2018 IPR027413 GroEL-like equatorial domain CFK41_RS12615 a3a4fc06ffa18ce2a27c6dadc7ab6b80 528 Gene3D G3DSA:3.50.7.10 191 371 2.5E-89 T 28-03-2018 IPR027409 GroEL-like apical domain CFK41_RS12615 a3a4fc06ffa18ce2a27c6dadc7ab6b80 528 Hamap MF_00600 60 kDa chaperonin [groL]. 1 528 39.399 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CFK41_RS12615 a3a4fc06ffa18ce2a27c6dadc7ab6b80 528 SUPERFAMILY SSF48592 318 521 3.21E-32 T 28-03-2018 CFK41_RS12615 a3a4fc06ffa18ce2a27c6dadc7ab6b80 528 Gene3D G3DSA:1.10.560.10 1 190 2.5E-39 T 28-03-2018 IPR027413 GroEL-like equatorial domain CFK41_RS12615 a3a4fc06ffa18ce2a27c6dadc7ab6b80 528 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 28-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CFK41_RS12615 a3a4fc06ffa18ce2a27c6dadc7ab6b80 528 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 2.7E-236 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CFK41_RS12615 a3a4fc06ffa18ce2a27c6dadc7ab6b80 528 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 1.5E-94 T 28-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CFK41_RS02020 6abdfe854d400d25aea404e49ee0bb8f 416 Pfam PF02386 Cation transport protein 14 395 1.0E-55 T 28-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 CFK41_RS17240 5d7eea17590427fe8f51792a7426f26d 447 Gene3D G3DSA:3.40.640.10 104 328 6.1E-31 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS17240 5d7eea17590427fe8f51792a7426f26d 447 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 1.2E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS17240 5d7eea17590427fe8f51792a7426f26d 447 SUPERFAMILY SSF46785 14 83 1.59E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS17240 5d7eea17590427fe8f51792a7426f26d 447 Gene3D G3DSA:3.90.1150.10 329 447 1.3E-13 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS17240 5d7eea17590427fe8f51792a7426f26d 447 Gene3D G3DSA:1.10.10.10 5 78 1.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS17240 5d7eea17590427fe8f51792a7426f26d 447 SUPERFAMILY SSF53383 82 444 3.88E-56 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS17240 5d7eea17590427fe8f51792a7426f26d 447 Pfam PF00155 Aminotransferase class I and II 101 439 3.2E-21 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CFK41_RS17240 5d7eea17590427fe8f51792a7426f26d 447 SMART SM00345 17 76 6.9E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS12000 47aed6cd7242c1a56f51a160b650e613 1098 Gene3D G3DSA:1.10.730.10 644 875 1.3E-53 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS12000 47aed6cd7242c1a56f51a160b650e613 1098 Gene3D G3DSA:3.40.50.620 430 643 7.0E-59 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS12000 47aed6cd7242c1a56f51a160b650e613 1098 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 3 1087 13.467 T 28-03-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CFK41_RS12000 47aed6cd7242c1a56f51a160b650e613 1098 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 53 64 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS12000 47aed6cd7242c1a56f51a160b650e613 1098 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 23 681 8.8E-165 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS12000 47aed6cd7242c1a56f51a160b650e613 1098 Gene3D G3DSA:3.40.50.620 33 211 4.7E-33 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS12000 47aed6cd7242c1a56f51a160b650e613 1098 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 14 892 1.0E-237 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CFK41_RS12000 47aed6cd7242c1a56f51a160b650e613 1098 SUPERFAMILY SSF50677 208 433 4.4E-34 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CFK41_RS12000 47aed6cd7242c1a56f51a160b650e613 1098 SUPERFAMILY SSF47323 701 912 1.23E-39 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS12000 47aed6cd7242c1a56f51a160b650e613 1098 Gene3D G3DSA:3.90.740.10 212 429 1.5E-47 T 28-03-2018 CFK41_RS12000 47aed6cd7242c1a56f51a160b650e613 1098 Pfam PF08264 Anticodon-binding domain of tRNA 742 879 3.7E-24 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CFK41_RS12000 47aed6cd7242c1a56f51a160b650e613 1098 SUPERFAMILY SSF52374 433 680 1.32E-127 T 28-03-2018 CFK41_RS12000 47aed6cd7242c1a56f51a160b650e613 1098 SUPERFAMILY SSF52374 13 203 1.32E-127 T 28-03-2018 CFK41_RS12000 47aed6cd7242c1a56f51a160b650e613 1098 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 566 579 2.3E-21 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CFK41_RS12000 47aed6cd7242c1a56f51a160b650e613 1098 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 606 615 2.3E-21 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CFK41_RS12000 47aed6cd7242c1a56f51a160b650e613 1098 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 236 259 2.3E-21 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CFK41_RS12000 47aed6cd7242c1a56f51a160b650e613 1098 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 46 57 2.3E-21 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CFK41_RS05225 efe0fc3fae6e756ef5d65087e2992211 183 SUPERFAMILY SSF50475 20 181 2.55E-39 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CFK41_RS05225 efe0fc3fae6e756ef5d65087e2992211 183 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 146 182 8.1E-9 T 28-03-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CFK41_RS05225 efe0fc3fae6e756ef5d65087e2992211 183 Gene3D G3DSA:2.30.110.10 150 183 5.0E-8 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CFK41_RS05225 efe0fc3fae6e756ef5d65087e2992211 183 Gene3D G3DSA:2.30.110.10 39 149 2.9E-32 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CFK41_RS05225 efe0fc3fae6e756ef5d65087e2992211 183 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 47 123 2.8E-18 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CFK41_RS05225 efe0fc3fae6e756ef5d65087e2992211 183 PIRSF PIRSF000190 2 145 2.1E-35 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CFK41_RS05225 efe0fc3fae6e756ef5d65087e2992211 183 PIRSF PIRSF000190 140 183 4.9E-8 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CFK41_RS16050 afa1e74d27010a736a95d7764d2829f5 298 SUPERFAMILY SSF51735 1 296 1.4E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS16050 afa1e74d27010a736a95d7764d2829f5 298 Gene3D G3DSA:3.40.50.720 132 291 2.9E-12 T 28-03-2018 CFK41_RS16050 afa1e74d27010a736a95d7764d2829f5 298 Gene3D G3DSA:3.30.1780.10 1 131 5.5E-31 T 28-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CFK41_RS16050 afa1e74d27010a736a95d7764d2829f5 298 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 8 193 1.6E-20 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CFK41_RS02820 47bc3ac7cee5bd3164d7cf5db9069d04 250 Gene3D G3DSA:3.40.50.1820 1 248 4.0E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS02820 47bc3ac7cee5bd3164d7cf5db9069d04 250 Pfam PF12146 Serine aminopeptidase, S33 31 132 8.6E-11 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CFK41_RS02820 47bc3ac7cee5bd3164d7cf5db9069d04 250 SUPERFAMILY SSF53474 181 249 1.92E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS02820 47bc3ac7cee5bd3164d7cf5db9069d04 250 SUPERFAMILY SSF53474 3 137 1.92E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS13400 a6d5690634d181aea28d15f4956fca77 370 SUPERFAMILY SSF51679 10 365 8.64E-84 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CFK41_RS13400 a6d5690634d181aea28d15f4956fca77 370 Pfam PF00296 Luciferase-like monooxygenase 9 339 1.0E-75 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CFK41_RS13400 a6d5690634d181aea28d15f4956fca77 370 Gene3D G3DSA:3.20.20.30 9 369 9.9E-83 T 28-03-2018 CFK41_RS02670 e9b301e904c6bd9135d138c549ab3467 381 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 13 127 1.1E-16 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS02670 e9b301e904c6bd9135d138c549ab3467 381 Gene3D G3DSA:3.30.360.10 149 363 1.3E-35 T 28-03-2018 CFK41_RS02670 e9b301e904c6bd9135d138c549ab3467 381 SUPERFAMILY SSF55347 138 330 1.01E-27 T 28-03-2018 CFK41_RS02670 e9b301e904c6bd9135d138c549ab3467 381 Gene3D G3DSA:3.40.50.720 4 148 6.5E-31 T 28-03-2018 CFK41_RS02670 e9b301e904c6bd9135d138c549ab3467 381 SUPERFAMILY SSF51735 6 162 6.5E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS03935 60a34c73e457a2c98b4b6ed2d24254bf 213 SUPERFAMILY SSF69593 5 210 1.11E-42 T 28-03-2018 CFK41_RS03935 60a34c73e457a2c98b4b6ed2d24254bf 213 Pfam PF01553 Acyltransferase 23 153 2.3E-25 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CFK41_RS03935 60a34c73e457a2c98b4b6ed2d24254bf 213 SMART SM00563 37 156 4.9E-34 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CFK41_RS03935 60a34c73e457a2c98b4b6ed2d24254bf 213 Gene3D G3DSA:3.40.1130.10 3 212 2.5E-48 T 28-03-2018 CFK41_RS08765 f804a4fb7d378bc420ccd8004ca86af1 181 Pfam PF04186 FxsA cytoplasmic membrane protein 27 131 2.5E-13 T 28-03-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 CFK41_RS11505 a7e989f40636d7af6fd9edc30dce3036 366 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 17 353 3.0E-94 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CFK41_RS11505 a7e989f40636d7af6fd9edc30dce3036 366 ProSitePatterns PS01348 MraY family signature 2. 182 193 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CFK41_RS11505 a7e989f40636d7af6fd9edc30dce3036 366 ProSitePatterns PS01347 MraY family signature 1. 46 58 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CFK41_RS11505 a7e989f40636d7af6fd9edc30dce3036 366 Pfam PF00953 Glycosyl transferase family 4 81 283 3.3E-34 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CFK41_RS11505 a7e989f40636d7af6fd9edc30dce3036 366 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 46 58 7.1E-6 T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CFK41_RS11505 a7e989f40636d7af6fd9edc30dce3036 366 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 357 22.908 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CFK41_RS12980 44f08a6c8dd37435400951d819c1fc49 253 Gene3D G3DSA:3.40.50.150 3 251 1.4E-29 T 28-03-2018 CFK41_RS12980 44f08a6c8dd37435400951d819c1fc49 253 Pfam PF13649 Methyltransferase domain 46 138 6.7E-12 T 28-03-2018 CFK41_RS12980 44f08a6c8dd37435400951d819c1fc49 253 SUPERFAMILY SSF53335 12 245 4.11E-28 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS07930 0b3d74782da58932a7a8a690d06e74d8 652 Gene3D G3DSA:3.30.1360.60 403 478 3.2E-23 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CFK41_RS07930 0b3d74782da58932a7a8a690d06e74d8 652 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 523 646 8.5E-47 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CFK41_RS07930 0b3d74782da58932a7a8a690d06e74d8 652 Pfam PF02378 Phosphotransferase system, EIIC 9 314 5.9E-69 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CFK41_RS07930 0b3d74782da58932a7a8a690d06e74d8 652 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 525 643 1.0E-40 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CFK41_RS07930 0b3d74782da58932a7a8a690d06e74d8 652 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 417 434 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CFK41_RS07930 0b3d74782da58932a7a8a690d06e74d8 652 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 374 464 7.9E-17 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CFK41_RS07930 0b3d74782da58932a7a8a690d06e74d8 652 Pfam PF00367 phosphotransferase system, EIIB 408 439 3.4E-11 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CFK41_RS07930 0b3d74782da58932a7a8a690d06e74d8 652 SUPERFAMILY SSF51261 517 648 2.79E-47 T 28-03-2018 IPR011055 Duplicated hybrid motif CFK41_RS07930 0b3d74782da58932a7a8a690d06e74d8 652 TIGRFAM TIGR01998 PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component 2 475 2.6E-172 T 28-03-2018 IPR010974 Phosphotransferase system, N-acetylglucosamine-specific IIBC component GO:0008982|GO:0009401|GO:0015572|GO:0016021|GO:0019866 CFK41_RS07930 0b3d74782da58932a7a8a690d06e74d8 652 Gene3D G3DSA:2.70.70.10 512 652 5.2E-51 T 28-03-2018 CFK41_RS07930 0b3d74782da58932a7a8a690d06e74d8 652 SUPERFAMILY SSF55604 405 478 2.22E-18 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CFK41_RS07930 0b3d74782da58932a7a8a690d06e74d8 652 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 585 597 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CFK41_RS11820 2cc8bea7c7a7009d37cebee0db024093 436 Gene3D G3DSA:3.20.20.70 62 390 8.2E-32 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS11820 2cc8bea7c7a7009d37cebee0db024093 436 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 53 407 65.199 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CFK41_RS11820 2cc8bea7c7a7009d37cebee0db024093 436 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 55 410 9.7E-95 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CFK41_RS11820 2cc8bea7c7a7009d37cebee0db024093 436 SUPERFAMILY SSF102114 148 366 1.83E-14 T 28-03-2018 CFK41_RS11820 2cc8bea7c7a7009d37cebee0db024093 436 PIRSF PIRSF006004 42 421 1.4E-115 T 28-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CFK41_RS11820 2cc8bea7c7a7009d37cebee0db024093 436 Pfam PF04055 Radical SAM superfamily 161 330 1.9E-13 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CFK41_RS01075 9aa77076470ba9b62d9e969b1a8077e4 283 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS01075 9aa77076470ba9b62d9e969b1a8077e4 283 SMART SM00382 27 212 2.8E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS01075 9aa77076470ba9b62d9e969b1a8077e4 283 Pfam PF00005 ABC transporter 19 163 7.9E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS01075 9aa77076470ba9b62d9e969b1a8077e4 283 SUPERFAMILY SSF52540 2 239 1.54E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS01075 9aa77076470ba9b62d9e969b1a8077e4 283 Gene3D G3DSA:3.40.50.300 1 251 4.2E-70 T 28-03-2018 CFK41_RS15515 53258ee2d3971b6629d1255de330df56 93 PRINTS PR00107 Phosphocarrier protein signature 13 29 6.8E-11 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CFK41_RS15515 53258ee2d3971b6629d1255de330df56 93 PRINTS PR00107 Phosphocarrier protein signature 39 54 6.8E-11 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CFK41_RS15515 53258ee2d3971b6629d1255de330df56 93 PRINTS PR00107 Phosphocarrier protein signature 54 71 6.8E-11 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CFK41_RS15515 53258ee2d3971b6629d1255de330df56 93 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 28-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site CFK41_RS15515 53258ee2d3971b6629d1255de330df56 93 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 83 3.3E-23 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CFK41_RS15515 53258ee2d3971b6629d1255de330df56 93 Gene3D G3DSA:3.30.1340.10 1 88 1.7E-26 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CFK41_RS15515 53258ee2d3971b6629d1255de330df56 93 SUPERFAMILY SSF55594 1 88 1.7E-21 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CFK41_RS15515 53258ee2d3971b6629d1255de330df56 93 Pfam PF00381 PTS HPr component phosphorylation site 4 83 1.4E-24 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CFK41_RS04605 d03b2d98d0089258b0476bad45e428a6 280 SUPERFAMILY SSF54814 2 110 3.14E-33 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CFK41_RS04605 d03b2d98d0089258b0476bad45e428a6 280 SUPERFAMILY SSF54821 111 210 1.7E-35 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04605 d03b2d98d0089258b0476bad45e428a6 280 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 214 9.9E-91 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CFK41_RS04605 d03b2d98d0089258b0476bad45e428a6 280 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 210 37.763 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CFK41_RS04605 d03b2d98d0089258b0476bad45e428a6 280 Gene3D G3DSA:3.30.1140.32 112 212 5.0E-34 T 28-03-2018 CFK41_RS04605 d03b2d98d0089258b0476bad45e428a6 280 Pfam PF07650 KH domain 43 114 2.3E-18 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04605 d03b2d98d0089258b0476bad45e428a6 280 Pfam PF00189 Ribosomal protein S3, C-terminal domain 124 206 4.1E-35 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04605 d03b2d98d0089258b0476bad45e428a6 280 SMART SM00322 64 129 2.9E-6 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CFK41_RS04605 d03b2d98d0089258b0476bad45e428a6 280 ProSitePatterns PS00548 Ribosomal protein S3 signature. 167 201 - T 28-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04605 d03b2d98d0089258b0476bad45e428a6 280 Gene3D G3DSA:3.30.300.20 17 111 5.4E-29 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CFK41_RS12840 56351ec38f82639415fce03a2ef6b05b 720 SUPERFAMILY SSF50993 19 451 1.7E-42 T 28-03-2018 CFK41_RS12840 56351ec38f82639415fce03a2ef6b05b 720 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 518 542 1.1E-45 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CFK41_RS12840 56351ec38f82639415fce03a2ef6b05b 720 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 491 509 1.1E-45 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CFK41_RS12840 56351ec38f82639415fce03a2ef6b05b 720 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 546 565 1.1E-45 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CFK41_RS12840 56351ec38f82639415fce03a2ef6b05b 720 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 649 671 1.1E-45 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CFK41_RS12840 56351ec38f82639415fce03a2ef6b05b 720 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 576 596 1.1E-45 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CFK41_RS12840 56351ec38f82639415fce03a2ef6b05b 720 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 630 645 1.1E-45 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CFK41_RS12840 56351ec38f82639415fce03a2ef6b05b 720 SUPERFAMILY SSF53474 458 713 3.41E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS12840 56351ec38f82639415fce03a2ef6b05b 720 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 18 425 6.9E-22 T 28-03-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 CFK41_RS12840 56351ec38f82639415fce03a2ef6b05b 720 Gene3D G3DSA:2.130.10.120 78 431 5.9E-23 T 28-03-2018 CFK41_RS12840 56351ec38f82639415fce03a2ef6b05b 720 Gene3D G3DSA:3.40.50.1820 432 719 1.6E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS12840 56351ec38f82639415fce03a2ef6b05b 720 Pfam PF00326 Prolyl oligopeptidase family 515 717 1.1E-46 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CFK41_RS02680 7919aa22c59d2ab7ccb9bf0153e5010d 223 Gene3D G3DSA:1.10.357.10 93 222 1.8E-14 T 28-03-2018 CFK41_RS02680 7919aa22c59d2ab7ccb9bf0153e5010d 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 69 92 4.7E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS02680 7919aa22c59d2ab7ccb9bf0153e5010d 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 61 4.7E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS02680 7919aa22c59d2ab7ccb9bf0153e5010d 223 Gene3D G3DSA:1.10.10.60 9 92 4.8E-20 T 28-03-2018 CFK41_RS02680 7919aa22c59d2ab7ccb9bf0153e5010d 223 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 155 206 8.8E-7 T 28-03-2018 CFK41_RS02680 7919aa22c59d2ab7ccb9bf0153e5010d 223 SUPERFAMILY SSF48498 129 218 3.89E-15 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CFK41_RS02680 7919aa22c59d2ab7ccb9bf0153e5010d 223 SUPERFAMILY SSF46689 40 100 3.14E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS02680 7919aa22c59d2ab7ccb9bf0153e5010d 223 Pfam PF00440 Bacterial regulatory proteins, tetR family 48 94 3.4E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS04780 2244f3a617f3a35b32681fe64e396aa5 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 71 1.0E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS04780 2244f3a617f3a35b32681fe64e396aa5 222 Gene3D G3DSA:1.10.357.10 109 215 2.4E-5 T 28-03-2018 CFK41_RS04780 2244f3a617f3a35b32681fe64e396aa5 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 1.1E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS04780 2244f3a617f3a35b32681fe64e396aa5 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 1.1E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS04780 2244f3a617f3a35b32681fe64e396aa5 222 SUPERFAMILY SSF48498 101 176 1.96E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CFK41_RS04780 2244f3a617f3a35b32681fe64e396aa5 222 SUPERFAMILY SSF46689 15 90 2.36E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS04780 2244f3a617f3a35b32681fe64e396aa5 222 Gene3D G3DSA:1.10.10.60 12 55 6.3E-16 T 28-03-2018 CFK41_RS04780 2244f3a617f3a35b32681fe64e396aa5 222 Gene3D G3DSA:1.10.260.40 56 108 9.8E-10 T 28-03-2018 CFK41_RS08385 b321149135451b11eb2ff739804d398d 333 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 242 330 8.5E-29 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CFK41_RS08385 b321149135451b11eb2ff739804d398d 333 SUPERFAMILY SSF53901 15 330 5.34E-61 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CFK41_RS08385 b321149135451b11eb2ff739804d398d 333 Gene3D G3DSA:3.40.47.10 174 331 1.5E-34 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CFK41_RS08385 b321149135451b11eb2ff739804d398d 333 Gene3D G3DSA:3.40.47.10 12 173 2.5E-31 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CFK41_RS08385 b321149135451b11eb2ff739804d398d 333 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 117 194 7.3E-26 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CFK41_RS08385 b321149135451b11eb2ff739804d398d 333 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 15 330 1.4E-92 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CFK41_RS08970 879f4ebc5fd67dc6a7cad08528812d3f 339 SUPERFAMILY SSF53335 150 299 1.47E-28 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS08970 879f4ebc5fd67dc6a7cad08528812d3f 339 Gene3D G3DSA:3.40.50.150 145 324 8.7E-28 T 28-03-2018 CFK41_RS08970 879f4ebc5fd67dc6a7cad08528812d3f 339 Pfam PF01170 Putative RNA methylase family UPF0020 159 330 7.9E-23 T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CFK41_RS08970 879f4ebc5fd67dc6a7cad08528812d3f 339 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 258 264 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CFK41_RS16335 5865a07ba7431431426a4ebd81c1b99b 559 SUPERFAMILY SSF53850 31 38 1.74E-44 T 28-03-2018 CFK41_RS16335 5865a07ba7431431426a4ebd81c1b99b 559 SUPERFAMILY SSF53850 95 557 1.74E-44 T 28-03-2018 CFK41_RS16335 5865a07ba7431431426a4ebd81c1b99b 559 Gene3D G3DSA:3.40.190.10 232 559 5.2E-21 T 28-03-2018 CFK41_RS16335 5865a07ba7431431426a4ebd81c1b99b 559 Pfam PF13416 Bacterial extracellular solute-binding protein 116 341 3.3E-9 T 28-03-2018 CFK41_RS16335 5865a07ba7431431426a4ebd81c1b99b 559 Gene3D G3DSA:3.40.190.10 91 231 3.9E-13 T 28-03-2018 CFK41_RS02285 1503030e2fff73f6ff14f2bc86d44081 756 Pfam PF04542 Sigma-70 region 2 71 137 6.8E-8 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS02285 1503030e2fff73f6ff14f2bc86d44081 756 Pfam PF13490 Putative zinc-finger 235 268 1.5E-5 T 28-03-2018 IPR027383 Putative zinc-finger CFK41_RS02285 1503030e2fff73f6ff14f2bc86d44081 756 Gene3D G3DSA:1.10.1740.10 44 128 6.2E-17 T 28-03-2018 CFK41_RS02285 1503030e2fff73f6ff14f2bc86d44081 756 Gene3D G3DSA:2.60.40.1310 524 658 1.8E-7 T 28-03-2018 CFK41_RS02285 1503030e2fff73f6ff14f2bc86d44081 756 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 68 219 1.3E-18 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS02285 1503030e2fff73f6ff14f2bc86d44081 756 SUPERFAMILY SSF88946 48 147 7.06E-16 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS02285 1503030e2fff73f6ff14f2bc86d44081 756 Pfam PF08281 Sigma-70, region 4 167 214 8.0E-7 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS02285 1503030e2fff73f6ff14f2bc86d44081 756 SUPERFAMILY SSF88659 161 219 6.54E-10 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS02285 1503030e2fff73f6ff14f2bc86d44081 756 Gene3D G3DSA:1.10.10.10 129 224 3.8E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS00530 14c63b3163d8cde0d2ae71b7c13c0a19 630 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 410 483 5.3E-6 T 28-03-2018 IPR018905 Alpha-galactosidase, NEW3 domain CFK41_RS00530 14c63b3163d8cde0d2ae71b7c13c0a19 630 Gene3D G3DSA:2.60.40.10 395 504 5.1E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS00530 14c63b3163d8cde0d2ae71b7c13c0a19 630 Gene3D G3DSA:1.50.10.20 39 391 1.1E-56 T 28-03-2018 CFK41_RS00530 14c63b3163d8cde0d2ae71b7c13c0a19 630 Pfam PF03663 Glycosyl hydrolase family 76 64 384 2.8E-44 T 28-03-2018 IPR005198 Glycoside hydrolase, family 76 KEGG: 00052+3.2.1.10|KEGG: 00500+3.2.1.10 CFK41_RS00530 14c63b3163d8cde0d2ae71b7c13c0a19 630 SUPERFAMILY SSF48208 51 347 2.45E-44 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CFK41_RS07045 86a510bf6cdcd4327788f9a43054be8d 181 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 30 173 8.1E-31 T 28-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 CFK41_RS07045 86a510bf6cdcd4327788f9a43054be8d 181 Hamap MF_01398 ATP synthase subunit b [atpF]. 19 154 12.569 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CFK41_RS07045 86a510bf6cdcd4327788f9a43054be8d 181 Gene3D G3DSA:1.20.5.620 78 138 2.1E-9 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CFK41_RS07045 86a510bf6cdcd4327788f9a43054be8d 181 SUPERFAMILY SSF81573 78 137 2.88E-10 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CFK41_RS07045 86a510bf6cdcd4327788f9a43054be8d 181 Pfam PF00430 ATP synthase B/B' CF(0) 23 152 1.8E-28 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CFK41_RS15330 659332c9f488b08d7d03d84a08769194 318 Pfam PF04545 Sigma-70, region 4 15 48 7.6E-7 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS15330 659332c9f488b08d7d03d84a08769194 318 Gene3D G3DSA:3.40.50.1360 53 316 8.6E-35 T 28-03-2018 CFK41_RS15330 659332c9f488b08d7d03d84a08769194 318 Pfam PF04198 Putative sugar-binding domain 65 316 1.7E-51 T 28-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 CFK41_RS15330 659332c9f488b08d7d03d84a08769194 318 SUPERFAMILY SSF46689 14 74 4.48E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS15330 659332c9f488b08d7d03d84a08769194 318 SUPERFAMILY SSF100950 67 315 1.17E-51 T 28-03-2018 CFK41_RS15330 659332c9f488b08d7d03d84a08769194 318 Gene3D G3DSA:1.10.10.60 1 52 1.2E-15 T 28-03-2018 CFK41_RS16920 eaa6c7ce6ced87257615ad37ae5b35e3 366 Pfam PF00294 pfkB family carbohydrate kinase 186 327 3.7E-26 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CFK41_RS16920 eaa6c7ce6ced87257615ad37ae5b35e3 366 Pfam PF00294 pfkB family carbohydrate kinase 7 159 5.4E-17 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CFK41_RS16920 eaa6c7ce6ced87257615ad37ae5b35e3 366 SUPERFAMILY SSF53613 5 330 3.38E-59 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS16920 eaa6c7ce6ced87257615ad37ae5b35e3 366 Gene3D G3DSA:3.40.1190.20 6 339 8.0E-72 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS10805 eb79daee00f8f61be754d6424018c722 525 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 316 516 2.3E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS10805 eb79daee00f8f61be754d6424018c722 525 Gene3D G3DSA:1.20.58.370 10 101 1.3E-16 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CFK41_RS10805 eb79daee00f8f61be754d6424018c722 525 SUPERFAMILY SSF160964 20 276 1.09E-49 T 28-03-2018 CFK41_RS10805 eb79daee00f8f61be754d6424018c722 525 Pfam PF16296 N-terminal of TM subunit in PBP-dependent ABC transporters 80 161 2.3E-26 T 28-03-2018 IPR032550 PBP-dependent ABC transporters TM subunit, N-terminal CFK41_RS10805 eb79daee00f8f61be754d6424018c722 525 SUPERFAMILY SSF161098 277 511 1.06E-54 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS10805 eb79daee00f8f61be754d6424018c722 525 Gene3D G3DSA:3.10.650.10 206 285 5.7E-15 T 28-03-2018 CFK41_RS10805 eb79daee00f8f61be754d6424018c722 525 Gene3D G3DSA:1.10.3720.10 286 519 4.7E-47 T 28-03-2018 CFK41_RS01175 4eabc893f98218155ec9b3db345896cd 673 Gene3D G3DSA:1.50.10.10 255 442 7.0E-24 T 28-03-2018 CFK41_RS01175 4eabc893f98218155ec9b3db345896cd 673 Gene3D G3DSA:1.50.10.10 443 672 5.1E-37 T 28-03-2018 CFK41_RS01175 4eabc893f98218155ec9b3db345896cd 673 Pfam PF06202 Amylo-alpha-1,6-glucosidase 287 662 4.0E-7 T 28-03-2018 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-6798695|Reactome: R-HSA-70221 CFK41_RS01175 4eabc893f98218155ec9b3db345896cd 673 SUPERFAMILY SSF48208 283 667 3.26E-58 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CFK41_RS01175 4eabc893f98218155ec9b3db345896cd 673 Pfam PF14742 N-terminal domain of (some) glycogen debranching enzymes 39 213 4.9E-14 T 28-03-2018 IPR032856 Putative glycogen debranching enzyme, N-terminal CFK41_RS10915 cb55d5df9d54193705be65282c29c9a0 145 SUPERFAMILY SSF49299 13 75 5.49E-8 T 28-03-2018 IPR000601 PKD domain CFK41_RS10915 cb55d5df9d54193705be65282c29c9a0 145 Pfam PF00801 PKD domain 26 71 1.5E-5 T 28-03-2018 IPR000601 PKD domain CFK41_RS10915 cb55d5df9d54193705be65282c29c9a0 145 Gene3D G3DSA:2.60.40.10 2 101 3.7E-9 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS01885 c2bf10e7e73fe80355adc5e4e69cf9f1 210 Pfam PF13671 AAA domain 3 142 4.8E-19 T 28-03-2018 CFK41_RS01885 c2bf10e7e73fe80355adc5e4e69cf9f1 210 SUPERFAMILY SSF52540 5 166 4.47E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS01885 c2bf10e7e73fe80355adc5e4e69cf9f1 210 Gene3D G3DSA:3.40.50.300 2 174 1.1E-19 T 28-03-2018 CFK41_RS00860 77a2235184d3eab2447363197c749767 609 Pfam PF00144 Beta-lactamase 104 431 3.6E-62 T 28-03-2018 IPR001466 Beta-lactamase-related CFK41_RS00860 77a2235184d3eab2447363197c749767 609 Gene3D G3DSA:3.40.710.10 67 452 3.2E-88 T 28-03-2018 CFK41_RS00860 77a2235184d3eab2447363197c749767 609 SUPERFAMILY SSF56601 80 428 1.03E-81 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CFK41_RS06635 b86671d5908493ff11f7936d798d7e97 215 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 12 213 44.477 T 28-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 CFK41_RS06635 b86671d5908493ff11f7936d798d7e97 215 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 14 204 1.4E-44 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CFK41_RS06635 b86671d5908493ff11f7936d798d7e97 215 SUPERFAMILY SSF52972 12 206 1.44E-59 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CFK41_RS06635 b86671d5908493ff11f7936d798d7e97 215 Pfam PF01725 Ham1 family 14 204 1.3E-52 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CFK41_RS06635 b86671d5908493ff11f7936d798d7e97 215 Gene3D G3DSA:3.90.950.10 2 209 6.6E-74 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CFK41_RS04990 62535cfdfbc0acd1131668bb82d17584 436 Gene3D G3DSA:3.40.50.300 224 430 5.3E-18 T 28-03-2018 CFK41_RS04990 62535cfdfbc0acd1131668bb82d17584 436 Pfam PF13638 PIN domain 12 150 1.1E-30 T 28-03-2018 IPR002716 PIN domain CFK41_RS04990 62535cfdfbc0acd1131668bb82d17584 436 Gene3D G3DSA:3.40.50.1010 9 182 5.5E-32 T 28-03-2018 IPR029060 PIN domain-like CFK41_RS04990 62535cfdfbc0acd1131668bb82d17584 436 Pfam PF02562 PhoH-like protein 226 430 9.4E-56 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 CFK41_RS04990 62535cfdfbc0acd1131668bb82d17584 436 SUPERFAMILY SSF52540 225 406 4.95E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS04990 62535cfdfbc0acd1131668bb82d17584 436 SUPERFAMILY SSF88723 102 149 3.92E-10 T 28-03-2018 IPR029060 PIN domain-like CFK41_RS04990 62535cfdfbc0acd1131668bb82d17584 436 SUPERFAMILY SSF88723 11 69 3.92E-10 T 28-03-2018 IPR029060 PIN domain-like CFK41_RS04990 62535cfdfbc0acd1131668bb82d17584 436 SMART SM00670 10 137 3.4E-13 T 28-03-2018 IPR002716 PIN domain CFK41_RS13045 135827d67a7c8c6866293a84bb7a488b 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 278 1.2E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS13045 135827d67a7c8c6866293a84bb7a488b 281 SUPERFAMILY SSF161098 78 266 3.27E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS13045 135827d67a7c8c6866293a84bb7a488b 281 Gene3D G3DSA:1.10.3720.10 6 273 7.7E-41 T 28-03-2018 CFK41_RS11185 923dbf5b4e7ee99cd7b13fd4a728ed85 383 SUPERFAMILY SSF54211 248 360 1.9E-18 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CFK41_RS11185 923dbf5b4e7ee99cd7b13fd4a728ed85 383 Pfam PF13180 PDZ domain 170 237 1.8E-9 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CFK41_RS11185 923dbf5b4e7ee99cd7b13fd4a728ed85 383 Gene3D G3DSA:3.30.230.10 75 381 1.2E-39 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CFK41_RS11185 923dbf5b4e7ee99cd7b13fd4a728ed85 383 SUPERFAMILY SSF50156 173 271 3.42E-17 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CFK41_RS11185 923dbf5b4e7ee99cd7b13fd4a728ed85 383 SMART SM00228 163 229 7.6E-6 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CFK41_RS11185 923dbf5b4e7ee99cd7b13fd4a728ed85 383 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 270 354 6.4E-7 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CFK41_RS04085 08b05041726a687f6e677f0cef61a140 322 SMART SM00829 10 320 5.6E-9 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CFK41_RS04085 08b05041726a687f6e677f0cef61a140 322 Pfam PF13602 Zinc-binding dehydrogenase 187 320 7.6E-13 T 28-03-2018 CFK41_RS04085 08b05041726a687f6e677f0cef61a140 322 SUPERFAMILY SSF51735 115 264 9.38E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS04085 08b05041726a687f6e677f0cef61a140 322 SUPERFAMILY SSF50129 1 148 1.83E-33 T 28-03-2018 IPR011032 GroES-like CFK41_RS04085 08b05041726a687f6e677f0cef61a140 322 Gene3D G3DSA:3.40.50.720 141 263 1.7E-21 T 28-03-2018 CFK41_RS04085 08b05041726a687f6e677f0cef61a140 322 Gene3D G3DSA:3.90.180.10 1 140 5.5E-36 T 28-03-2018 CFK41_RS04085 08b05041726a687f6e677f0cef61a140 322 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 84 1.1E-5 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CFK41_RS01395 fad6bd9d9f4e3496c9cd02c4203ee354 645 SUPERFAMILY SSF49452 350 442 2.55E-9 T 28-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 CFK41_RS01395 fad6bd9d9f4e3496c9cd02c4203ee354 645 SUPERFAMILY SSF49785 465 642 2.55E-17 T 28-03-2018 IPR008979 Galactose-binding domain-like CFK41_RS01395 fad6bd9d9f4e3496c9cd02c4203ee354 645 Pfam PF14686 Polysaccharide lyase family 4, domain II 379 439 1.6E-11 T 28-03-2018 IPR029413 Rhamnogalacturonan lyase, domain II CFK41_RS01395 fad6bd9d9f4e3496c9cd02c4203ee354 645 Gene3D G3DSA:2.60.40.1120 350 451 1.4E-10 T 28-03-2018 CFK41_RS01395 fad6bd9d9f4e3496c9cd02c4203ee354 645 Gene3D G3DSA:2.60.120.260 462 644 5.0E-29 T 28-03-2018 IPR008979 Galactose-binding domain-like CFK41_RS01395 fad6bd9d9f4e3496c9cd02c4203ee354 645 Gene3D G3DSA:2.70.98.10 38 349 5.1E-33 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CFK41_RS01395 fad6bd9d9f4e3496c9cd02c4203ee354 645 Pfam PF14683 Polysaccharide lyase family 4, domain III 465 642 6.7E-20 T 28-03-2018 IPR029411 Rhamnogalacturonan lyase, domain III CFK41_RS01395 fad6bd9d9f4e3496c9cd02c4203ee354 645 SUPERFAMILY SSF74650 40 321 3.45E-13 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CFK41_RS09170 d828c096aeeab34d4ff15293501e1e39 300 Pfam PF01479 S4 domain 61 104 5.0E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CFK41_RS09170 d828c096aeeab34d4ff15293501e1e39 300 SUPERFAMILY SSF55120 117 295 1.03E-38 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CFK41_RS09170 d828c096aeeab34d4ff15293501e1e39 300 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 160 174 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CFK41_RS09170 d828c096aeeab34d4ff15293501e1e39 300 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 127 287 2.6E-44 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CFK41_RS09170 d828c096aeeab34d4ff15293501e1e39 300 Gene3D G3DSA:3.10.290.10 56 117 1.1E-17 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CFK41_RS09170 d828c096aeeab34d4ff15293501e1e39 300 Pfam PF00849 RNA pseudouridylate synthase 124 257 7.0E-21 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CFK41_RS09170 d828c096aeeab34d4ff15293501e1e39 300 Gene3D G3DSA:3.30.70.580 118 203 2.3E-18 T 28-03-2018 CFK41_RS09170 d828c096aeeab34d4ff15293501e1e39 300 Gene3D G3DSA:3.30.70.1560 204 274 6.9E-16 T 28-03-2018 CFK41_RS09170 d828c096aeeab34d4ff15293501e1e39 300 SMART SM00363 61 120 5.9E-11 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CFK41_RS09170 d828c096aeeab34d4ff15293501e1e39 300 SUPERFAMILY SSF55174 57 126 1.0E-13 T 28-03-2018 CFK41_RS13470 a8135ffec9bb233f9e539516a88b93e9 288 SUPERFAMILY SSF56784 29 287 1.32E-50 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS13470 a8135ffec9bb233f9e539516a88b93e9 288 ProSitePatterns PS01229 Hypothetical cof family signature 2. 237 259 - T 28-03-2018 CFK41_RS13470 a8135ffec9bb233f9e539516a88b93e9 288 Pfam PF08282 haloacid dehalogenase-like hydrolase 33 280 2.5E-43 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS13470 a8135ffec9bb233f9e539516a88b93e9 288 Gene3D G3DSA:3.40.50.1000 7 288 2.2E-38 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS13470 a8135ffec9bb233f9e539516a88b93e9 288 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 31 256 4.5E-21 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CFK41_RS06080 69803d3595386fd872b1dc2449356d8f 571 SUPERFAMILY SSF53738 312 448 4.71E-26 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS06080 69803d3595386fd872b1dc2449356d8f 571 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 149 163 6.8E-5 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS06080 69803d3595386fd872b1dc2449356d8f 571 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 304 319 6.8E-5 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS06080 69803d3595386fd872b1dc2449356d8f 571 SUPERFAMILY SSF53738 45 222 9.42E-39 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS06080 69803d3595386fd872b1dc2449356d8f 571 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 150 159 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS06080 69803d3595386fd872b1dc2449356d8f 571 Gene3D G3DSA:3.40.120.10 20 221 6.7E-56 T 28-03-2018 CFK41_RS06080 69803d3595386fd872b1dc2449356d8f 571 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 456 532 2.9E-7 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS06080 69803d3595386fd872b1dc2449356d8f 571 SUPERFAMILY SSF55957 452 540 4.97E-15 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS06080 69803d3595386fd872b1dc2449356d8f 571 Gene3D G3DSA:3.30.310.50 450 571 4.4E-17 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS06080 69803d3595386fd872b1dc2449356d8f 571 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 53 195 6.0E-35 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS06080 69803d3595386fd872b1dc2449356d8f 571 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 230 320 4.4E-23 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS06080 69803d3595386fd872b1dc2449356d8f 571 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 333 435 3.4E-14 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS06080 69803d3595386fd872b1dc2449356d8f 571 SUPERFAMILY SSF53738 219 320 2.43E-20 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CFK41_RS06080 69803d3595386fd872b1dc2449356d8f 571 Gene3D G3DSA:3.40.120.10 345 448 1.3E-31 T 28-03-2018 CFK41_RS06080 69803d3595386fd872b1dc2449356d8f 571 Gene3D G3DSA:3.40.120.10 222 344 2.7E-28 T 28-03-2018 CFK41_RS00285 7fcf8ed9510c065cf165c343f9b63522 424 Gene3D G3DSA:1.20.1250.20 211 413 2.9E-15 T 28-03-2018 CFK41_RS00285 7fcf8ed9510c065cf165c343f9b63522 424 Gene3D G3DSA:1.20.1250.20 1 205 1.8E-25 T 28-03-2018 CFK41_RS00285 7fcf8ed9510c065cf165c343f9b63522 424 SUPERFAMILY SSF103473 3 406 6.67E-40 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS00285 7fcf8ed9510c065cf165c343f9b63522 424 Pfam PF07690 Major Facilitator Superfamily 15 356 6.6E-26 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS06315 9d02ed35d8d498753a2c7ffe7bc5ffd4 342 Gene3D G3DSA:3.40.50.300 45 211 2.5E-27 T 28-03-2018 CFK41_RS06315 9d02ed35d8d498753a2c7ffe7bc5ffd4 342 Gene3D G3DSA:1.10.8.300 230 338 1.3E-31 T 28-03-2018 CFK41_RS06315 9d02ed35d8d498753a2c7ffe7bc5ffd4 342 PIRSF PIRSF002849 16 342 2.6E-126 T 28-03-2018 CFK41_RS06315 9d02ed35d8d498753a2c7ffe7bc5ffd4 342 SUPERFAMILY SSF52540 25 314 1.58E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS06315 9d02ed35d8d498753a2c7ffe7bc5ffd4 342 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 64 194 1.2E-63 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CFK41_RS03365 9d4eeec5b3c1acc6c05804ceacd2b5e6 367 SUPERFAMILY SSF47090 84 149 3.4E-16 T 28-03-2018 IPR002477 Peptidoglycan binding-like CFK41_RS03365 9d4eeec5b3c1acc6c05804ceacd2b5e6 367 Pfam PF01471 Putative peptidoglycan binding domain 171 226 1.2E-12 T 28-03-2018 IPR002477 Peptidoglycan binding-like CFK41_RS03365 9d4eeec5b3c1acc6c05804ceacd2b5e6 367 Pfam PF01471 Putative peptidoglycan binding domain 95 149 5.0E-12 T 28-03-2018 IPR002477 Peptidoglycan binding-like CFK41_RS03365 9d4eeec5b3c1acc6c05804ceacd2b5e6 367 SUPERFAMILY SSF47090 161 226 7.06E-16 T 28-03-2018 IPR002477 Peptidoglycan binding-like CFK41_RS03365 9d4eeec5b3c1acc6c05804ceacd2b5e6 367 SUPERFAMILY SSF54001 249 363 2.89E-33 T 28-03-2018 CFK41_RS03365 9d4eeec5b3c1acc6c05804ceacd2b5e6 367 Pfam PF00877 NlpC/P60 family 265 353 1.8E-22 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CFK41_RS03365 9d4eeec5b3c1acc6c05804ceacd2b5e6 367 Gene3D G3DSA:1.10.101.10 83 158 4.3E-20 T 28-03-2018 IPR002477 Peptidoglycan binding-like CFK41_RS03365 9d4eeec5b3c1acc6c05804ceacd2b5e6 367 Gene3D G3DSA:1.10.101.10 159 231 1.3E-19 T 28-03-2018 IPR002477 Peptidoglycan binding-like CFK41_RS03365 9d4eeec5b3c1acc6c05804ceacd2b5e6 367 Gene3D G3DSA:3.90.1720.10 246 363 6.9E-32 T 28-03-2018 CFK41_RS14975 9cf6b5f0d525ade5e0132ec1cf38ead1 573 SUPERFAMILY SSF51905 12 234 1.13E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS14975 9cf6b5f0d525ade5e0132ec1cf38ead1 573 Pfam PF13454 FAD-NAD(P)-binding 17 177 1.1E-28 T 28-03-2018 CFK41_RS14975 9cf6b5f0d525ade5e0132ec1cf38ead1 573 Gene3D G3DSA:3.50.50.60 8 201 6.8E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS09260 28998aea4d4daf80f3853c21b2981cbb 586 SMART SM00482 326 546 1.1E-9 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CFK41_RS09260 28998aea4d4daf80f3853c21b2981cbb 586 Pfam PF00476 DNA polymerase family A 236 564 5.2E-24 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CFK41_RS09260 28998aea4d4daf80f3853c21b2981cbb 586 SUPERFAMILY SSF56672 170 564 5.11E-57 T 28-03-2018 CFK41_RS09260 28998aea4d4daf80f3853c21b2981cbb 586 Gene3D G3DSA:3.30.70.370 300 585 7.7E-22 T 28-03-2018 CFK41_RS16375 21231a1a352a29fa46ce2f37451b4c6f 397 TIGRFAM TIGR02631 xylA_Arthro: xylose isomerase 6 393 7.4E-185 T 28-03-2018 IPR013453 Xylose isomerase, actinobacteria GO:0009045|GO:0042732 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CFK41_RS16375 21231a1a352a29fa46ce2f37451b4c6f 397 Gene3D G3DSA:3.20.20.150 5 395 1.6E-69 T 28-03-2018 CFK41_RS16375 21231a1a352a29fa46ce2f37451b4c6f 397 Pfam PF01261 Xylose isomerase-like TIM barrel 42 266 5.6E-21 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS16375 21231a1a352a29fa46ce2f37451b4c6f 397 PRINTS PR00688 Xylose isomerase signature 179 203 2.7E-57 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CFK41_RS16375 21231a1a352a29fa46ce2f37451b4c6f 397 PRINTS PR00688 Xylose isomerase signature 130 151 2.7E-57 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CFK41_RS16375 21231a1a352a29fa46ce2f37451b4c6f 397 PRINTS PR00688 Xylose isomerase signature 288 299 2.7E-57 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CFK41_RS16375 21231a1a352a29fa46ce2f37451b4c6f 397 PRINTS PR00688 Xylose isomerase signature 157 176 2.7E-57 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CFK41_RS16375 21231a1a352a29fa46ce2f37451b4c6f 397 PRINTS PR00688 Xylose isomerase signature 249 260 2.7E-57 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CFK41_RS16375 21231a1a352a29fa46ce2f37451b4c6f 397 PRINTS PR00688 Xylose isomerase signature 221 248 2.7E-57 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CFK41_RS16375 21231a1a352a29fa46ce2f37451b4c6f 397 PRINTS PR00688 Xylose isomerase signature 83 103 2.7E-57 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CFK41_RS16375 21231a1a352a29fa46ce2f37451b4c6f 397 PRINTS PR00688 Xylose isomerase signature 46 68 2.7E-57 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CFK41_RS16375 21231a1a352a29fa46ce2f37451b4c6f 397 PRINTS PR00688 Xylose isomerase signature 106 125 2.7E-57 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CFK41_RS16375 21231a1a352a29fa46ce2f37451b4c6f 397 Hamap MF_00455 Xylose isomerase [xylA]. 1 392 31.079 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CFK41_RS16375 21231a1a352a29fa46ce2f37451b4c6f 397 SUPERFAMILY SSF51658 5 394 2.63E-97 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS07080 b07d97988e4868cd58607589ef9a3147 412 Pfam PF01979 Amidohydrolase family 67 396 3.7E-23 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CFK41_RS07080 b07d97988e4868cd58607589ef9a3147 412 SUPERFAMILY SSF51338 381 411 5.4E-8 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS07080 b07d97988e4868cd58607589ef9a3147 412 SUPERFAMILY SSF51338 23 70 5.4E-8 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS07080 b07d97988e4868cd58607589ef9a3147 412 Gene3D G3DSA:3.20.20.140 86 381 4.4E-91 T 28-03-2018 CFK41_RS07080 b07d97988e4868cd58607589ef9a3147 412 Gene3D G3DSA:2.30.40.10 19 85 5.9E-10 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS07080 b07d97988e4868cd58607589ef9a3147 412 PIRSF PIRSF038994 21 412 8.9E-87 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CFK41_RS07080 b07d97988e4868cd58607589ef9a3147 412 SUPERFAMILY SSF51556 71 381 5.26E-75 T 28-03-2018 IPR032466 Metal-dependent hydrolase CFK41_RS03685 78b40e42500bc653316068afa2cbc815 326 SUPERFAMILY SSF48371 110 167 4.32E-17 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CFK41_RS03685 78b40e42500bc653316068afa2cbc815 326 SUPERFAMILY SSF48371 201 297 4.32E-17 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CFK41_RS03685 78b40e42500bc653316068afa2cbc815 326 Gene3D G3DSA:1.25.40.70 245 294 5.2E-7 T 28-03-2018 CFK41_RS03685 78b40e42500bc653316068afa2cbc815 326 Pfam PF13646 HEAT repeats 211 289 2.4E-8 T 28-03-2018 CFK41_RS03685 78b40e42500bc653316068afa2cbc815 326 SMART SM00567 E-Z type HEAT repeats 216 245 66.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CFK41_RS03685 78b40e42500bc653316068afa2cbc815 326 SMART SM00567 E-Z type HEAT repeats 248 277 0.72 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CFK41_RS03685 78b40e42500bc653316068afa2cbc815 326 Gene3D G3DSA:1.25.10.10 10 244 3.1E-9 T 28-03-2018 IPR011989 Armadillo-like helical CFK41_RS06725 0502f20f94c65a07f5a7889a9f472818 766 SUPERFAMILY SSF55008 14 80 2.62E-17 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CFK41_RS06725 0502f20f94c65a07f5a7889a9f472818 766 Pfam PF00702 haloacid dehalogenase-like hydrolase 440 656 1.2E-47 T 28-03-2018 CFK41_RS06725 0502f20f94c65a07f5a7889a9f472818 766 Gene3D G3DSA:3.30.70.100 4 89 1.5E-19 T 28-03-2018 CFK41_RS06725 0502f20f94c65a07f5a7889a9f472818 766 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 208 745 1.1E-151 T 28-03-2018 CFK41_RS06725 0502f20f94c65a07f5a7889a9f472818 766 Pfam PF00122 E1-E2 ATPase 247 422 1.6E-51 T 28-03-2018 CFK41_RS06725 0502f20f94c65a07f5a7889a9f472818 766 SUPERFAMILY SSF56784 442 462 1.65E-57 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS06725 0502f20f94c65a07f5a7889a9f472818 766 SUPERFAMILY SSF56784 501 742 1.65E-57 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS06725 0502f20f94c65a07f5a7889a9f472818 766 Pfam PF00403 Heavy-metal-associated domain 18 75 8.7E-13 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CFK41_RS06725 0502f20f94c65a07f5a7889a9f472818 766 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 446 452 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CFK41_RS06725 0502f20f94c65a07f5a7889a9f472818 766 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 444 458 4.7E-26 T 28-03-2018 CFK41_RS06725 0502f20f94c65a07f5a7889a9f472818 766 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 567 578 4.7E-26 T 28-03-2018 CFK41_RS06725 0502f20f94c65a07f5a7889a9f472818 766 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 589 599 4.7E-26 T 28-03-2018 CFK41_RS06725 0502f20f94c65a07f5a7889a9f472818 766 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 642 661 4.7E-26 T 28-03-2018 CFK41_RS06725 0502f20f94c65a07f5a7889a9f472818 766 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 665 677 4.7E-26 T 28-03-2018 CFK41_RS06725 0502f20f94c65a07f5a7889a9f472818 766 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 294 308 4.7E-26 T 28-03-2018 CFK41_RS06725 0502f20f94c65a07f5a7889a9f472818 766 SUPERFAMILY SSF81665 691 720 7.59E-14 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CFK41_RS06725 0502f20f94c65a07f5a7889a9f472818 766 SUPERFAMILY SSF81665 345 438 7.59E-14 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CFK41_RS06725 0502f20f94c65a07f5a7889a9f472818 766 SUPERFAMILY SSF81665 206 248 7.59E-14 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CFK41_RS06725 0502f20f94c65a07f5a7889a9f472818 766 ProSitePatterns PS01047 Heavy-metal-associated domain. 20 48 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CFK41_RS06725 0502f20f94c65a07f5a7889a9f472818 766 Gene3D G3DSA:3.40.1110.10 459 571 1.4E-29 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CFK41_RS06725 0502f20f94c65a07f5a7889a9f472818 766 Gene3D G3DSA:3.40.50.1000 572 701 9.1E-38 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS06725 0502f20f94c65a07f5a7889a9f472818 766 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 218 722 1.1E-87 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CFK41_RS06725 0502f20f94c65a07f5a7889a9f472818 766 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 614 630 8.5E-10 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CFK41_RS06725 0502f20f94c65a07f5a7889a9f472818 766 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 504 522 8.5E-10 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CFK41_RS06725 0502f20f94c65a07f5a7889a9f472818 766 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 642 658 8.5E-10 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CFK41_RS06725 0502f20f94c65a07f5a7889a9f472818 766 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 673 698 8.5E-10 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CFK41_RS06725 0502f20f94c65a07f5a7889a9f472818 766 Gene3D G3DSA:1.20.1110.10 205 458 3.3E-49 T 28-03-2018 CFK41_RS06725 0502f20f94c65a07f5a7889a9f472818 766 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 163 744 3.2E-177 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CFK41_RS06725 0502f20f94c65a07f5a7889a9f472818 766 SUPERFAMILY SSF81653 250 344 3.66E-24 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CFK41_RS06020 12ec358990e74f5fab1c133db7a77e2c 371 SUPERFAMILY SSF53822 81 215 4.12E-7 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS06020 12ec358990e74f5fab1c133db7a77e2c 371 Gene3D G3DSA:3.40.50.2300 165 369 4.9E-37 T 28-03-2018 CFK41_RS06020 12ec358990e74f5fab1c133db7a77e2c 371 Gene3D G3DSA:3.40.50.2300 41 164 2.0E-33 T 28-03-2018 CFK41_RS06020 12ec358990e74f5fab1c133db7a77e2c 371 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 45 360 1.6E-48 T 28-03-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 CFK41_RS13015 737cfbbc09e22ce61eda1dcd4308059a 322 Gene3D G3DSA:1.20.1510.10 12 210 8.8E-39 T 28-03-2018 CFK41_RS13015 737cfbbc09e22ce61eda1dcd4308059a 322 SUPERFAMILY SSF161111 14 212 6.54E-50 T 28-03-2018 CFK41_RS13015 737cfbbc09e22ce61eda1dcd4308059a 322 SUPERFAMILY SSF160240 214 294 1.24E-16 T 28-03-2018 CFK41_RS13015 737cfbbc09e22ce61eda1dcd4308059a 322 Pfam PF01545 Cation efflux family 18 211 8.8E-38 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CFK41_RS13015 737cfbbc09e22ce61eda1dcd4308059a 322 Gene3D G3DSA:3.30.70.1350 211 300 5.1E-18 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CFK41_RS13015 737cfbbc09e22ce61eda1dcd4308059a 322 Pfam PF16916 Dimerisation domain of Zinc Transporter 215 292 2.4E-18 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CFK41_RS13015 737cfbbc09e22ce61eda1dcd4308059a 322 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 15 284 4.9E-67 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CFK41_RS12780 9c55e81dee610cf72ec244a4fb16a1fa 276 Gene3D G3DSA:3.40.50.300 17 275 4.3E-73 T 28-03-2018 CFK41_RS12780 9c55e81dee610cf72ec244a4fb16a1fa 276 SMART SM00382 55 246 1.9E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS12780 9c55e81dee610cf72ec244a4fb16a1fa 276 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS12780 9c55e81dee610cf72ec244a4fb16a1fa 276 Pfam PF00005 ABC transporter 47 197 1.0E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS12780 9c55e81dee610cf72ec244a4fb16a1fa 276 SUPERFAMILY SSF52540 22 268 8.1E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11980 ad9cd6c4f16447c9702852d78a3fd309 462 SUPERFAMILY SSF53623 17 314 1.14E-82 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CFK41_RS11980 ad9cd6c4f16447c9702852d78a3fd309 462 Gene3D G3DSA:3.40.1190.10 17 318 2.7E-80 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CFK41_RS11980 ad9cd6c4f16447c9702852d78a3fd309 462 TIGRFAM TIGR01499 folC: bifunctional protein FolC 38 455 3.6E-99 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CFK41_RS11980 ad9cd6c4f16447c9702852d78a3fd309 462 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 58 81 - T 28-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 CFK41_RS11980 ad9cd6c4f16447c9702852d78a3fd309 462 Gene3D G3DSA:3.90.190.20 319 460 1.2E-25 T 28-03-2018 CFK41_RS11980 ad9cd6c4f16447c9702852d78a3fd309 462 PIRSF PIRSF001563 13 461 3.2E-110 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CFK41_RS11980 ad9cd6c4f16447c9702852d78a3fd309 462 Pfam PF08245 Mur ligase middle domain 60 292 9.8E-19 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CFK41_RS11980 ad9cd6c4f16447c9702852d78a3fd309 462 Pfam PF02875 Mur ligase family, glutamate ligase domain 318 391 4.0E-8 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CFK41_RS11980 ad9cd6c4f16447c9702852d78a3fd309 462 SUPERFAMILY SSF53244 318 459 5.68E-23 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CFK41_RS12325 84fd648b0ddce8aaeeba988480f846a9 486 PIRSF PIRSF000130 1 486 5.0E-138 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CFK41_RS12325 84fd648b0ddce8aaeeba988480f846a9 486 SUPERFAMILY SSF51412 8 91 1.57E-89 T 28-03-2018 CFK41_RS12325 84fd648b0ddce8aaeeba988480f846a9 486 SUPERFAMILY SSF51412 204 468 1.57E-89 T 28-03-2018 CFK41_RS12325 84fd648b0ddce8aaeeba988480f846a9 486 Pfam PF00571 CBS domain 91 140 7.0E-4 T 28-03-2018 IPR000644 CBS domain CFK41_RS12325 84fd648b0ddce8aaeeba988480f846a9 486 TIGRFAM TIGR01303 IMP_DH_rel_1: IMP dehydrogenase family protein 5 482 8.6E-210 T 28-03-2018 IPR005991 IMP dehydrogenase-related 1 CFK41_RS12325 84fd648b0ddce8aaeeba988480f846a9 486 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 11 480 2.9E-101 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CFK41_RS12325 84fd648b0ddce8aaeeba988480f846a9 486 Gene3D G3DSA:3.20.20.70 3 475 2.1E-79 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS12325 84fd648b0ddce8aaeeba988480f846a9 486 SMART SM01240 9 481 9.1E-178 T 28-03-2018 CFK41_RS12325 84fd648b0ddce8aaeeba988480f846a9 486 SUPERFAMILY SSF54631 90 204 3.98E-14 T 28-03-2018 CFK41_RS06140 0eb0e61c48957c255b763f04e3884ddc 402 Gene3D G3DSA:3.40.50.20 15 101 3.9E-19 T 28-03-2018 CFK41_RS06140 0eb0e61c48957c255b763f04e3884ddc 402 SUPERFAMILY SSF51246 318 385 2.04E-16 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CFK41_RS06140 0eb0e61c48957c255b763f04e3884ddc 402 SUPERFAMILY SSF52440 14 110 1.44E-17 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CFK41_RS06140 0eb0e61c48957c255b763f04e3884ddc 402 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 18 374 2.0E-109 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CFK41_RS06140 0eb0e61c48957c255b763f04e3884ddc 402 Pfam PF02222 ATP-grasp domain 124 292 5.0E-47 T 28-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type CFK41_RS06140 0eb0e61c48957c255b763f04e3884ddc 402 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 17 371 37.853 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CFK41_RS06140 0eb0e61c48957c255b763f04e3884ddc 402 SUPERFAMILY SSF56059 115 312 7.78E-55 T 28-03-2018 CFK41_RS06140 0eb0e61c48957c255b763f04e3884ddc 402 Gene3D G3DSA:3.30.470.20 192 386 5.4E-46 T 28-03-2018 CFK41_RS06140 0eb0e61c48957c255b763f04e3884ddc 402 Gene3D G3DSA:3.30.1490.20 107 191 1.6E-13 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CFK41_RS11590 c1a877b116aa590832f44718553f1f47 234 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 189 201 4.9E-10 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CFK41_RS11590 c1a877b116aa590832f44718553f1f47 234 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 150 160 4.9E-10 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CFK41_RS11590 c1a877b116aa590832f44718553f1f47 234 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 161 172 4.9E-10 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CFK41_RS11590 c1a877b116aa590832f44718553f1f47 234 Gene3D G3DSA:1.10.10.10 23 88 1.1E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS11590 c1a877b116aa590832f44718553f1f47 234 TIGRFAM TIGR00498 lexA: repressor LexA 22 233 5.4E-74 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CFK41_RS11590 c1a877b116aa590832f44718553f1f47 234 SUPERFAMILY SSF51306 113 232 6.28E-34 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CFK41_RS11590 c1a877b116aa590832f44718553f1f47 234 Hamap MF_00015 LexA repressor [lexA]. 23 234 32.477 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CFK41_RS11590 c1a877b116aa590832f44718553f1f47 234 Pfam PF01726 LexA DNA binding domain 22 85 7.4E-26 T 28-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 CFK41_RS11590 c1a877b116aa590832f44718553f1f47 234 Pfam PF00717 Peptidase S24-like 153 214 3.7E-13 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CFK41_RS11590 c1a877b116aa590832f44718553f1f47 234 Gene3D G3DSA:2.10.109.10 119 234 2.1E-25 T 28-03-2018 CFK41_RS11590 c1a877b116aa590832f44718553f1f47 234 SUPERFAMILY SSF46785 23 89 1.03E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS01660 27d37ce2dfb9ce5229fcb05feeaa9347 267 SUPERFAMILY SSF55831 6 267 9.16E-125 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CFK41_RS01660 27d37ce2dfb9ce5229fcb05feeaa9347 267 Hamap MF_00008 Thymidylate synthase [thyA]. 4 267 39.373 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CFK41_RS01660 27d37ce2dfb9ce5229fcb05feeaa9347 267 ProSitePatterns PS00091 Thymidylate synthase active site. 129 157 - T 28-03-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CFK41_RS01660 27d37ce2dfb9ce5229fcb05feeaa9347 267 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 6 88 2.2E-37 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CFK41_RS01660 27d37ce2dfb9ce5229fcb05feeaa9347 267 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 87 267 1.8E-92 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CFK41_RS01660 27d37ce2dfb9ce5229fcb05feeaa9347 267 Gene3D G3DSA:3.30.572.10 4 267 2.4E-128 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CFK41_RS01660 27d37ce2dfb9ce5229fcb05feeaa9347 267 Pfam PF00303 Thymidylate synthase 6 267 1.7E-122 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CFK41_RS01660 27d37ce2dfb9ce5229fcb05feeaa9347 267 PRINTS PR00108 Thymidylate synthase family signature 118 137 1.2E-46 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CFK41_RS01660 27d37ce2dfb9ce5229fcb05feeaa9347 267 PRINTS PR00108 Thymidylate synthase family signature 144 159 1.2E-46 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CFK41_RS01660 27d37ce2dfb9ce5229fcb05feeaa9347 267 PRINTS PR00108 Thymidylate synthase family signature 45 66 1.2E-46 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CFK41_RS01660 27d37ce2dfb9ce5229fcb05feeaa9347 267 PRINTS PR00108 Thymidylate synthase family signature 200 217 1.2E-46 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CFK41_RS01660 27d37ce2dfb9ce5229fcb05feeaa9347 267 PRINTS PR00108 Thymidylate synthase family signature 162 188 1.2E-46 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CFK41_RS16380 7f98bba647f188d9e06d216b6351314b 396 Gene3D G3DSA:3.30.420.40 79 209 1.6E-17 T 28-03-2018 CFK41_RS16380 7f98bba647f188d9e06d216b6351314b 396 SUPERFAMILY SSF53067 209 384 1.57E-37 T 28-03-2018 CFK41_RS16380 7f98bba647f188d9e06d216b6351314b 396 Pfam PF00480 ROK family 84 373 4.1E-42 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CFK41_RS16380 7f98bba647f188d9e06d216b6351314b 396 Gene3D G3DSA:1.10.10.10 7 78 1.8E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS16380 7f98bba647f188d9e06d216b6351314b 396 SUPERFAMILY SSF53067 83 201 2.2E-13 T 28-03-2018 CFK41_RS16380 7f98bba647f188d9e06d216b6351314b 396 Gene3D G3DSA:3.30.420.40 210 384 1.2E-39 T 28-03-2018 CFK41_RS16380 7f98bba647f188d9e06d216b6351314b 396 SUPERFAMILY SSF46785 5 70 5.96E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS15500 a957f5335fcafe7c5a6f96d43236b0a7 452 SUPERFAMILY SSF55031 301 337 3.79E-11 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CFK41_RS15500 a957f5335fcafe7c5a6f96d43236b0a7 452 SUPERFAMILY SSF55031 215 260 3.79E-11 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CFK41_RS15500 a957f5335fcafe7c5a6f96d43236b0a7 452 PIRSF PIRSF036696 11 261 3.0E-29 T 28-03-2018 CFK41_RS15500 a957f5335fcafe7c5a6f96d43236b0a7 452 PIRSF PIRSF036696 294 442 3.2E-8 T 28-03-2018 CFK41_RS15500 a957f5335fcafe7c5a6f96d43236b0a7 452 Gene3D G3DSA:3.30.70.360 219 364 7.1E-23 T 28-03-2018 CFK41_RS15500 a957f5335fcafe7c5a6f96d43236b0a7 452 Pfam PF01546 Peptidase family M20/M25/M40 91 449 8.9E-33 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CFK41_RS15500 a957f5335fcafe7c5a6f96d43236b0a7 452 Pfam PF07687 Peptidase dimerisation domain 212 341 8.3E-17 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CFK41_RS15500 a957f5335fcafe7c5a6f96d43236b0a7 452 Gene3D G3DSA:3.40.630.10 7 218 1.3E-43 T 28-03-2018 CFK41_RS15500 a957f5335fcafe7c5a6f96d43236b0a7 452 SUPERFAMILY SSF53187 8 215 2.26E-52 T 28-03-2018 CFK41_RS15500 a957f5335fcafe7c5a6f96d43236b0a7 452 SUPERFAMILY SSF53187 362 449 2.26E-52 T 28-03-2018 CFK41_RS01335 cbc5d206c186009a3bb35a0cd7b40aa2 363 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 242 325 4.0E-23 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CFK41_RS01335 cbc5d206c186009a3bb35a0cd7b40aa2 363 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 244 313 2.1E-18 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CFK41_RS01335 cbc5d206c186009a3bb35a0cd7b40aa2 363 Pfam PF00005 ABC transporter 37 191 6.4E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS01335 cbc5d206c186009a3bb35a0cd7b40aa2 363 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS01335 cbc5d206c186009a3bb35a0cd7b40aa2 363 Gene3D G3DSA:3.40.50.300 13 336 1.1E-69 T 28-03-2018 CFK41_RS01335 cbc5d206c186009a3bb35a0cd7b40aa2 363 SUPERFAMILY SSF52540 16 264 1.13E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS01335 cbc5d206c186009a3bb35a0cd7b40aa2 363 SMART SM00382 45 244 1.7E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS00335 bf9d54de29e6305a3c9f38066cac072c 208 SUPERFAMILY SSF55729 22 199 2.44E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS00335 bf9d54de29e6305a3c9f38066cac072c 208 Pfam PF00583 Acetyltransferase (GNAT) family 106 182 4.7E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS00335 bf9d54de29e6305a3c9f38066cac072c 208 Gene3D G3DSA:3.40.630.30 18 208 2.3E-28 T 28-03-2018 CFK41_RS13025 27c28ac65540d9554a175e70594a49f0 493 Pfam PF01565 FAD binding domain 76 213 8.9E-39 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CFK41_RS13025 27c28ac65540d9554a175e70594a49f0 493 SUPERFAMILY SSF55103 253 492 8.99E-44 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CFK41_RS13025 27c28ac65540d9554a175e70594a49f0 493 Gene3D G3DSA:1.10.45.10 453 491 2.1E-12 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CFK41_RS13025 27c28ac65540d9554a175e70594a49f0 493 SUPERFAMILY SSF56176 62 250 1.73E-62 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CFK41_RS13025 27c28ac65540d9554a175e70594a49f0 493 Gene3D G3DSA:3.30.465.10 126 270 5.5E-40 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CFK41_RS13025 27c28ac65540d9554a175e70594a49f0 493 Gene3D G3DSA:3.30.43.10 10 125 3.5E-18 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CFK41_RS13025 27c28ac65540d9554a175e70594a49f0 493 Pfam PF02913 FAD linked oxidases, C-terminal domain 250 491 2.1E-45 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CFK41_RS12695 c22cb37c716ace52e44640dbe2631cfa 418 Gene3D G3DSA:2.170.190.11 49 148 2.9E-23 T 28-03-2018 CFK41_RS12695 c22cb37c716ace52e44640dbe2631cfa 418 SUPERFAMILY SSF53218 185 327 4.45E-29 T 28-03-2018 IPR001453 MoaB/Mog domain CFK41_RS12695 c22cb37c716ace52e44640dbe2631cfa 418 Gene3D G3DSA:3.40.980.10 157 335 1.4E-37 T 28-03-2018 IPR001453 MoaB/Mog domain CFK41_RS12695 c22cb37c716ace52e44640dbe2631cfa 418 Pfam PF00994 Probable molybdopterin binding domain 188 327 1.0E-18 T 28-03-2018 IPR001453 MoaB/Mog domain CFK41_RS12695 c22cb37c716ace52e44640dbe2631cfa 418 SUPERFAMILY SSF63882 17 182 9.94E-37 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CFK41_RS12695 c22cb37c716ace52e44640dbe2631cfa 418 SMART SM00852 187 328 1.3E-27 T 28-03-2018 IPR001453 MoaB/Mog domain CFK41_RS12695 c22cb37c716ace52e44640dbe2631cfa 418 Pfam PF03453 MoeA N-terminal region (domain I and II) 16 174 1.6E-32 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CFK41_RS09905 19067b6ccf3ed58e20e20d66c53999f1 603 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 2 582 32.123 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CFK41_RS09905 19067b6ccf3ed58e20e20d66c53999f1 603 SUPERFAMILY SSF55261 285 407 9.16E-35 T 28-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CFK41_RS09905 19067b6ccf3ed58e20e20d66c53999f1 603 Gene3D G3DSA:2.40.50.140 1 103 1.3E-25 T 28-03-2018 CFK41_RS09905 19067b6ccf3ed58e20e20d66c53999f1 603 Pfam PF02938 GAD domain 309 388 3.0E-15 T 28-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 CFK41_RS09905 19067b6ccf3ed58e20e20d66c53999f1 603 PRINTS PR01042 Aspartyl-tRNA synthetase signature 516 530 1.2E-25 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS09905 19067b6ccf3ed58e20e20d66c53999f1 603 PRINTS PR01042 Aspartyl-tRNA synthetase signature 204 217 1.2E-25 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS09905 19067b6ccf3ed58e20e20d66c53999f1 603 PRINTS PR01042 Aspartyl-tRNA synthetase signature 187 199 1.2E-25 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS09905 19067b6ccf3ed58e20e20d66c53999f1 603 PRINTS PR01042 Aspartyl-tRNA synthetase signature 472 488 1.2E-25 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS09905 19067b6ccf3ed58e20e20d66c53999f1 603 Pfam PF00152 tRNA synthetases class II (D, K and N) 115 555 4.2E-98 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS09905 19067b6ccf3ed58e20e20d66c53999f1 603 Gene3D G3DSA:3.30.930.10 128 584 3.7E-104 T 28-03-2018 CFK41_RS09905 19067b6ccf3ed58e20e20d66c53999f1 603 SUPERFAMILY SSF55681 394 555 8.36E-97 T 28-03-2018 CFK41_RS09905 19067b6ccf3ed58e20e20d66c53999f1 603 SUPERFAMILY SSF55681 115 307 8.36E-97 T 28-03-2018 CFK41_RS09905 19067b6ccf3ed58e20e20d66c53999f1 603 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 3 579 9.1E-210 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CFK41_RS09905 19067b6ccf3ed58e20e20d66c53999f1 603 SUPERFAMILY SSF50249 2 100 2.48E-28 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS09905 19067b6ccf3ed58e20e20d66c53999f1 603 Pfam PF01336 OB-fold nucleic acid binding domain 19 97 1.2E-12 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CFK41_RS16585 f56f1d3ee0a93e3b80eb35d33a08d74f 184 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 39 153 3.2E-10 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CFK41_RS16585 f56f1d3ee0a93e3b80eb35d33a08d74f 184 Gene3D G3DSA:3.30.530.20 14 183 3.4E-21 T 28-03-2018 IPR023393 START-like domain CFK41_RS16585 f56f1d3ee0a93e3b80eb35d33a08d74f 184 SUPERFAMILY SSF55961 25 163 1.1E-23 T 28-03-2018 CFK41_RS10825 b4ac40dd98089b14546071c129621cca 427 Gene3D G3DSA:3.30.470.20 129 417 9.6E-28 T 28-03-2018 CFK41_RS10825 b4ac40dd98089b14546071c129621cca 427 SUPERFAMILY SSF56059 136 336 4.77E-23 T 28-03-2018 CFK41_RS04380 5e0fe883ed1273244dec3355b24876eb 331 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 21 329 51.45 T 28-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 CFK41_RS04380 5e0fe883ed1273244dec3355b24876eb 331 SUPERFAMILY SSF52096 59 326 1.34E-71 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CFK41_RS04380 5e0fe883ed1273244dec3355b24876eb 331 TIGRFAM TIGR01929 menB: naphthoate synthase 60 326 3.1E-114 T 28-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 CFK41_RS04380 5e0fe883ed1273244dec3355b24876eb 331 Gene3D G3DSA:3.90.226.10 13 269 4.0E-61 T 28-03-2018 CFK41_RS04380 5e0fe883ed1273244dec3355b24876eb 331 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 167 187 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CFK41_RS04380 5e0fe883ed1273244dec3355b24876eb 331 Gene3D G3DSA:1.10.12.10 270 318 5.2E-16 T 28-03-2018 IPR014748 Crontonase, C-terminal CFK41_RS04380 5e0fe883ed1273244dec3355b24876eb 331 Pfam PF00378 Enoyl-CoA hydratase/isomerase 62 324 1.7E-54 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CFK41_RS15355 98bb034eee0a2d68f11c9b6ba2fd5ac7 286 SUPERFAMILY SSF54675 5 109 2.33E-30 T 28-03-2018 CFK41_RS15355 98bb034eee0a2d68f11c9b6ba2fd5ac7 286 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 110 279 5.0E-53 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CFK41_RS15355 98bb034eee0a2d68f11c9b6ba2fd5ac7 286 Gene3D G3DSA:3.20.20.70 131 270 6.6E-37 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS15355 98bb034eee0a2d68f11c9b6ba2fd5ac7 286 SUPERFAMILY SSF51690 110 280 9.03E-53 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CFK41_RS15355 98bb034eee0a2d68f11c9b6ba2fd5ac7 286 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 11 280 9.0E-91 T 28-03-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 CFK41_RS15355 98bb034eee0a2d68f11c9b6ba2fd5ac7 286 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 20 108 2.9E-26 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CFK41_RS15355 98bb034eee0a2d68f11c9b6ba2fd5ac7 286 Gene3D G3DSA:3.90.1170.20 1 130 4.8E-44 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CFK41_RS15355 98bb034eee0a2d68f11c9b6ba2fd5ac7 286 PIRSF PIRSF006250 1 283 3.8E-82 T 28-03-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 CFK41_RS16995 a5f29b6d30da57bde600326cf5e7d325 312 SUPERFAMILY SSF51556 25 303 5.76E-44 T 28-03-2018 IPR032466 Metal-dependent hydrolase CFK41_RS16995 a5f29b6d30da57bde600326cf5e7d325 312 Gene3D G3DSA:3.20.20.140 22 311 2.0E-41 T 28-03-2018 CFK41_RS16995 a5f29b6d30da57bde600326cf5e7d325 312 Pfam PF04909 Amidohydrolase 26 303 2.7E-26 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CFK41_RS00810 ac4ac9ee7d5dd14713f15fb93d63ad0d 484 PIRSF PIRSF006060 3 482 3.8E-77 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CFK41_RS00810 ac4ac9ee7d5dd14713f15fb93d63ad0d 484 Pfam PF13520 Amino acid permease 35 443 1.1E-43 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CFK41_RS13055 8500b766661574c7e3e96e0d9ffd158d 160 Gene3D G3DSA:3.40.630.30 2 159 1.4E-22 T 28-03-2018 CFK41_RS13055 8500b766661574c7e3e96e0d9ffd158d 160 Pfam PF00583 Acetyltransferase (GNAT) family 52 131 2.0E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS13055 8500b766661574c7e3e96e0d9ffd158d 160 SUPERFAMILY SSF55729 18 155 1.3E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS01555 6ac1eeaa20b5f65cfa530741aaf502a7 437 Gene3D G3DSA:3.20.20.70 1 336 2.1E-70 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS01555 6ac1eeaa20b5f65cfa530741aaf502a7 437 SUPERFAMILY SSF51011 342 436 1.58E-5 T 28-03-2018 CFK41_RS01555 6ac1eeaa20b5f65cfa530741aaf502a7 437 PRINTS PR00740 Glycosyl hydrolase family 27 signature 191 209 2.0E-11 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CFK41_RS01555 6ac1eeaa20b5f65cfa530741aaf502a7 437 PRINTS PR00740 Glycosyl hydrolase family 27 signature 291 312 2.0E-11 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CFK41_RS01555 6ac1eeaa20b5f65cfa530741aaf502a7 437 PRINTS PR00740 Glycosyl hydrolase family 27 signature 97 118 2.0E-11 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CFK41_RS01555 6ac1eeaa20b5f65cfa530741aaf502a7 437 PRINTS PR00740 Glycosyl hydrolase family 27 signature 3 22 2.0E-11 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CFK41_RS01555 6ac1eeaa20b5f65cfa530741aaf502a7 437 SUPERFAMILY SSF51445 4 115 4.56E-62 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS01555 6ac1eeaa20b5f65cfa530741aaf502a7 437 SUPERFAMILY SSF51445 150 333 4.56E-62 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS01555 6ac1eeaa20b5f65cfa530741aaf502a7 437 Pfam PF16499 Alpha galactosidase A 9 112 9.9E-5 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CFK41_RS01555 6ac1eeaa20b5f65cfa530741aaf502a7 437 Pfam PF16499 Alpha galactosidase A 158 333 3.1E-14 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CFK41_RS01555 6ac1eeaa20b5f65cfa530741aaf502a7 437 Gene3D G3DSA:2.60.40.1180 337 437 1.2E-13 T 28-03-2018 CFK41_RS02025 e3c549a37b4e80ada6996d4d68050014 233 SUPERFAMILY SSF116726 146 229 9.02E-15 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CFK41_RS02025 e3c549a37b4e80ada6996d4d68050014 233 Gene3D G3DSA:3.40.50.720 19 151 6.7E-23 T 28-03-2018 CFK41_RS02025 e3c549a37b4e80ada6996d4d68050014 233 Gene3D G3DSA:3.30.70.1450 152 232 1.5E-15 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CFK41_RS02025 e3c549a37b4e80ada6996d4d68050014 233 Pfam PF02080 TrkA-C domain 171 229 1.3E-8 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CFK41_RS02025 e3c549a37b4e80ada6996d4d68050014 233 Pfam PF02254 TrkA-N domain 21 136 6.0E-26 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CFK41_RS02025 e3c549a37b4e80ada6996d4d68050014 233 SUPERFAMILY SSF51735 20 149 2.91E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS11155 2f326049f735f7be2c07982e1b0f82ff 311 Pfam PF13622 Thioesterase-like superfamily 46 305 1.7E-53 T 28-03-2018 CFK41_RS11155 2f326049f735f7be2c07982e1b0f82ff 311 SUPERFAMILY SSF54637 140 306 6.22E-46 T 28-03-2018 IPR029069 HotDog domain CFK41_RS11155 2f326049f735f7be2c07982e1b0f82ff 311 SUPERFAMILY SSF54637 37 138 5.08E-28 T 28-03-2018 IPR029069 HotDog domain CFK41_RS11155 2f326049f735f7be2c07982e1b0f82ff 311 Gene3D G3DSA:3.10.129.10 153 309 2.2E-46 T 28-03-2018 CFK41_RS11155 2f326049f735f7be2c07982e1b0f82ff 311 Gene3D G3DSA:3.10.129.10 9 140 4.5E-34 T 28-03-2018 CFK41_RS16280 111a803602eab7d9ac2115df6ad173cd 317 SUPERFAMILY SSF161098 26 317 1.12E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS16280 111a803602eab7d9ac2115df6ad173cd 317 Gene3D G3DSA:1.10.3720.10 87 312 3.0E-31 T 28-03-2018 CFK41_RS16280 111a803602eab7d9ac2115df6ad173cd 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 129 310 1.5E-10 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS07675 be614656f7ce35f54900657e66e0fbda 564 SUPERFAMILY SSF52540 10 259 3.26E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS07675 be614656f7ce35f54900657e66e0fbda 564 ProSitePatterns PS00211 ABC transporters family signature. 436 450 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS07675 be614656f7ce35f54900657e66e0fbda 564 SUPERFAMILY SSF52540 304 535 7.93E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS07675 be614656f7ce35f54900657e66e0fbda 564 SMART SM00382 38 246 1.1E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS07675 be614656f7ce35f54900657e66e0fbda 564 SMART SM00382 320 513 5.3E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS07675 be614656f7ce35f54900657e66e0fbda 564 Gene3D G3DSA:3.40.50.300 286 559 9.4E-71 T 28-03-2018 CFK41_RS07675 be614656f7ce35f54900657e66e0fbda 564 Gene3D G3DSA:3.40.50.300 7 285 1.8E-69 T 28-03-2018 CFK41_RS07675 be614656f7ce35f54900657e66e0fbda 564 Pfam PF00005 ABC transporter 312 464 1.9E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS07675 be614656f7ce35f54900657e66e0fbda 564 Pfam PF00005 ABC transporter 30 187 1.8E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS07675 be614656f7ce35f54900657e66e0fbda 564 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 280 9.8E-4 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CFK41_RS07675 be614656f7ce35f54900657e66e0fbda 564 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 515 547 6.6E-4 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CFK41_RS07675 be614656f7ce35f54900657e66e0fbda 564 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS03650 61c3891e89f26edc1c74dbb1fb9b5596 346 SUPERFAMILY SSF53474 70 346 7.76E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS03650 61c3891e89f26edc1c74dbb1fb9b5596 346 Pfam PF00561 alpha/beta hydrolase fold 95 198 5.0E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CFK41_RS03650 61c3891e89f26edc1c74dbb1fb9b5596 346 Gene3D G3DSA:3.40.50.1820 62 346 7.6E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS13560 34aff8918b36ea4371f040b16b30f2b2 143 ProSitePatterns PS00519 AsnC-type HTH domain signature. 22 48 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CFK41_RS13560 34aff8918b36ea4371f040b16b30f2b2 143 SUPERFAMILY SSF46785 4 58 1.62E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS13560 34aff8918b36ea4371f040b16b30f2b2 143 SUPERFAMILY SSF54909 66 141 3.62E-15 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CFK41_RS13560 34aff8918b36ea4371f040b16b30f2b2 143 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 8.5E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CFK41_RS13560 34aff8918b36ea4371f040b16b30f2b2 143 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 8.5E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CFK41_RS13560 34aff8918b36ea4371f040b16b30f2b2 143 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 8.5E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CFK41_RS13560 34aff8918b36ea4371f040b16b30f2b2 143 SMART SM00344 4 110 8.5E-15 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CFK41_RS13560 34aff8918b36ea4371f040b16b30f2b2 143 Pfam PF13404 AsnC-type helix-turn-helix domain 4 44 9.5E-13 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CFK41_RS13560 34aff8918b36ea4371f040b16b30f2b2 143 Gene3D G3DSA:1.10.10.10 1 48 3.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS13560 34aff8918b36ea4371f040b16b30f2b2 143 Gene3D G3DSA:3.30.70.920 49 137 9.7E-20 T 28-03-2018 CFK41_RS13560 34aff8918b36ea4371f040b16b30f2b2 143 Pfam PF01037 Lrp/AsnC ligand binding domain 72 139 2.5E-15 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CFK41_RS03205 a3059a63e172634e850644aea66cfa72 812 Pfam PF01757 Acyltransferase family 140 483 3.1E-16 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CFK41_RS11290 dc1259c2a431b22f73f1333b3659b07e 217 Pfam PF13578 Methyltransferase domain 64 164 2.2E-10 T 28-03-2018 CFK41_RS11290 dc1259c2a431b22f73f1333b3659b07e 217 SUPERFAMILY SSF53335 40 215 4.58E-23 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS11290 dc1259c2a431b22f73f1333b3659b07e 217 Gene3D G3DSA:3.40.50.150 7 216 2.7E-23 T 28-03-2018 CFK41_RS07160 6583071838f72b0b454e1152302a9e18 374 Gene3D G3DSA:3.20.20.210 89 324 2.0E-5 T 28-03-2018 CFK41_RS16275 b667931d125d046a0f1cea9e815e61fa 364 Gene3D G3DSA:3.40.50.2300 89 206 7.3E-25 T 28-03-2018 CFK41_RS16275 b667931d125d046a0f1cea9e815e61fa 364 Gene3D G3DSA:1.10.10.10 18 45 0.0064 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS16275 b667931d125d046a0f1cea9e815e61fa 364 Gene3D G3DSA:1.10.260.40 46 88 6.6E-20 T 28-03-2018 CFK41_RS16275 b667931d125d046a0f1cea9e815e61fa 364 ProSitePatterns PS00356 LacI-type HTH domain signature. 35 53 - T 28-03-2018 CFK41_RS16275 b667931d125d046a0f1cea9e815e61fa 364 SMART SM00354 32 105 3.9E-24 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS16275 b667931d125d046a0f1cea9e815e61fa 364 Pfam PF00356 Bacterial regulatory proteins, lacI family 34 78 4.7E-16 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS16275 b667931d125d046a0f1cea9e815e61fa 364 Gene3D G3DSA:3.40.50.2300 207 364 6.6E-18 T 28-03-2018 CFK41_RS16275 b667931d125d046a0f1cea9e815e61fa 364 SUPERFAMILY SSF47413 32 90 1.36E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS16275 b667931d125d046a0f1cea9e815e61fa 364 SUPERFAMILY SSF53822 89 349 2.08E-32 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS16275 b667931d125d046a0f1cea9e815e61fa 364 Pfam PF13377 Periplasmic binding protein-like domain 198 362 1.2E-20 T 28-03-2018 CFK41_RS15020 6e1c0a54d557a28e25004c9f71255d4b 296 Pfam PF13560 Helix-turn-helix domain 18 85 1.0E-8 T 28-03-2018 CFK41_RS15020 6e1c0a54d557a28e25004c9f71255d4b 296 SMART SM00530 6 82 2.7E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CFK41_RS15020 6e1c0a54d557a28e25004c9f71255d4b 296 SUPERFAMILY SSF47413 31 81 4.57E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS15020 6e1c0a54d557a28e25004c9f71255d4b 296 Gene3D G3DSA:1.10.260.40 1 93 5.4E-10 T 28-03-2018 CFK41_RS04435 da6de5ab5fad2f29c03d28311967ac4d 301 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 53 281 1.7E-113 T 28-03-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 CFK41_RS04435 da6de5ab5fad2f29c03d28311967ac4d 301 Gene3D G3DSA:3.40.50.300 6 298 6.6E-99 T 28-03-2018 CFK41_RS04435 da6de5ab5fad2f29c03d28311967ac4d 301 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 54 280 1.4E-102 T 28-03-2018 IPR022488 Polyphosphate kinase-2-related CFK41_RS04435 da6de5ab5fad2f29c03d28311967ac4d 301 PIRSF PIRSF028756 24 301 5.5E-119 T 28-03-2018 IPR016898 Polyphosphate kinase 2 CFK41_RS04435 da6de5ab5fad2f29c03d28311967ac4d 301 SUPERFAMILY SSF52540 85 271 1.36E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS05700 d6607b9edebf20b3265d312ab50eb09e 300 Gene3D G3DSA:3.40.1280.10 146 300 7.6E-42 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CFK41_RS05700 d6607b9edebf20b3265d312ab50eb09e 300 Pfam PF00588 SpoU rRNA Methylase family 151 290 3.5E-35 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CFK41_RS05700 d6607b9edebf20b3265d312ab50eb09e 300 SUPERFAMILY SSF75217 142 296 4.38E-39 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CFK41_RS05700 d6607b9edebf20b3265d312ab50eb09e 300 Gene3D G3DSA:3.30.1330.30 2 130 9.0E-28 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CFK41_RS05700 d6607b9edebf20b3265d312ab50eb09e 300 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 38 95 9.2E-6 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CFK41_RS05700 d6607b9edebf20b3265d312ab50eb09e 300 SUPERFAMILY SSF55315 10 95 1.41E-10 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CFK41_RS05700 d6607b9edebf20b3265d312ab50eb09e 300 SMART SM00967 37 132 0.0076 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CFK41_RS12870 497ae7ea73f2c67d84f48e9f031d5cce 495 Pfam PF13396 Phospholipase_D-nuclease N-terminal 31 66 3.4E-8 T 28-03-2018 IPR027379 Cardiolipin synthase N-terminal CFK41_RS12870 497ae7ea73f2c67d84f48e9f031d5cce 495 SUPERFAMILY SSF56024 108 323 7.85E-42 T 28-03-2018 CFK41_RS12870 497ae7ea73f2c67d84f48e9f031d5cce 495 SUPERFAMILY SSF56024 282 481 7.18E-43 T 28-03-2018 CFK41_RS12870 497ae7ea73f2c67d84f48e9f031d5cce 495 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 25 494 7.4E-96 T 28-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 CFK41_RS12870 497ae7ea73f2c67d84f48e9f031d5cce 495 Pfam PF13091 PLD-like domain 336 457 4.1E-21 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CFK41_RS12870 497ae7ea73f2c67d84f48e9f031d5cce 495 Pfam PF13091 PLD-like domain 144 253 4.5E-9 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CFK41_RS12870 497ae7ea73f2c67d84f48e9f031d5cce 495 Gene3D G3DSA:3.30.870.10 125 314 1.9E-25 T 28-03-2018 CFK41_RS12870 497ae7ea73f2c67d84f48e9f031d5cce 495 Gene3D G3DSA:3.30.870.10 315 480 5.3E-20 T 28-03-2018 CFK41_RS12870 497ae7ea73f2c67d84f48e9f031d5cce 495 SMART SM00155 227 254 5.6 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CFK41_RS12870 497ae7ea73f2c67d84f48e9f031d5cce 495 SMART SM00155 408 435 0.026 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CFK41_RS01245 7e7d42273a124c7c1f3bd87a5fd2dfdd 552 Pfam PF00005 ABC transporter 309 467 1.8E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS01245 7e7d42273a124c7c1f3bd87a5fd2dfdd 552 Pfam PF00005 ABC transporter 21 176 4.1E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS01245 7e7d42273a124c7c1f3bd87a5fd2dfdd 552 SUPERFAMILY SSF52540 288 539 8.14E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS01245 7e7d42273a124c7c1f3bd87a5fd2dfdd 552 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 519 547 3.4E-6 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CFK41_RS01245 7e7d42273a124c7c1f3bd87a5fd2dfdd 552 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 227 267 1.3E-5 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CFK41_RS01245 7e7d42273a124c7c1f3bd87a5fd2dfdd 552 SUPERFAMILY SSF52540 8 232 1.68E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS01245 7e7d42273a124c7c1f3bd87a5fd2dfdd 552 ProSitePatterns PS00211 ABC transporters family signature. 440 454 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS01245 7e7d42273a124c7c1f3bd87a5fd2dfdd 552 Gene3D G3DSA:3.40.50.300 1 283 2.6E-67 T 28-03-2018 CFK41_RS01245 7e7d42273a124c7c1f3bd87a5fd2dfdd 552 Gene3D G3DSA:3.40.50.300 284 551 8.4E-72 T 28-03-2018 CFK41_RS01245 7e7d42273a124c7c1f3bd87a5fd2dfdd 552 SMART SM00382 29 225 2.8E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS01245 7e7d42273a124c7c1f3bd87a5fd2dfdd 552 SMART SM00382 317 517 1.7E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS07810 b1c5dd8996e80d0bf207969464216d20 374 Gene3D G3DSA:3.30.360.10 144 341 7.2E-26 T 28-03-2018 CFK41_RS07810 b1c5dd8996e80d0bf207969464216d20 374 SUPERFAMILY SSF55347 138 276 4.25E-16 T 28-03-2018 CFK41_RS07810 b1c5dd8996e80d0bf207969464216d20 374 Gene3D G3DSA:3.40.50.720 5 143 2.6E-24 T 28-03-2018 CFK41_RS07810 b1c5dd8996e80d0bf207969464216d20 374 SUPERFAMILY SSF51735 5 162 4.29E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS07810 b1c5dd8996e80d0bf207969464216d20 374 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 11 132 2.2E-12 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS01420 454fe3911407579a55aada92b0e2e6fd 282 SUPERFAMILY SSF161098 36 265 7.96E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01420 454fe3911407579a55aada92b0e2e6fd 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 69 274 2.3E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01420 454fe3911407579a55aada92b0e2e6fd 282 Gene3D G3DSA:1.10.3720.10 1 278 4.0E-34 T 28-03-2018 CFK41_RS01710 c97eede638d4d34ceb4d2d51194d03ab 654 SMART SM00354 7 77 2.9E-23 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS01710 c97eede638d4d34ceb4d2d51194d03ab 654 Gene3D G3DSA:3.40.50.2300 179 312 2.0E-31 T 28-03-2018 CFK41_RS01710 c97eede638d4d34ceb4d2d51194d03ab 654 SUPERFAMILY SSF53822 64 312 2.14E-51 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS01710 c97eede638d4d34ceb4d2d51194d03ab 654 SUPERFAMILY SSF47413 8 65 1.57E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS01710 c97eede638d4d34ceb4d2d51194d03ab 654 Pfam PF14100 Methane oxygenase PmoA 376 649 2.1E-53 T 28-03-2018 IPR029475 Methane oxygenase PmoA CFK41_RS01710 c97eede638d4d34ceb4d2d51194d03ab 654 Gene3D G3DSA:1.10.10.10 1 22 1.8E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS01710 c97eede638d4d34ceb4d2d51194d03ab 654 Gene3D G3DSA:3.40.50.2300 61 178 4.4E-36 T 28-03-2018 CFK41_RS01710 c97eede638d4d34ceb4d2d51194d03ab 654 Pfam PF00356 Bacterial regulatory proteins, lacI family 9 54 1.4E-14 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS01710 c97eede638d4d34ceb4d2d51194d03ab 654 Pfam PF13377 Periplasmic binding protein-like domain 172 336 2.1E-24 T 28-03-2018 CFK41_RS01710 c97eede638d4d34ceb4d2d51194d03ab 654 Gene3D G3DSA:1.10.260.40 23 60 6.7E-21 T 28-03-2018 CFK41_RS08120 3e6dbec42ad19bb74f01b80c302c534a 391 Pfam PF04055 Radical SAM superfamily 17 193 1.9E-21 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CFK41_RS08120 3e6dbec42ad19bb74f01b80c302c534a 391 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 14 349 6.0E-77 T 28-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 CFK41_RS08120 3e6dbec42ad19bb74f01b80c302c534a 391 SMART SM00729 12 240 6.3E-52 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CFK41_RS08120 3e6dbec42ad19bb74f01b80c302c534a 391 Gene3D G3DSA:3.20.20.70 4 331 2.1E-47 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS08120 3e6dbec42ad19bb74f01b80c302c534a 391 SUPERFAMILY SSF102114 7 389 2.35E-101 T 28-03-2018 CFK41_RS06280 454c5279e6d09c7d22e60534be486a0d 132 Pfam PF12005 Protein of unknown function (DUF3499) 3 128 1.7E-40 T 28-03-2018 IPR021888 Protein of unknown function DUF3499 CFK41_RS12605 d26e95287bbd49e1cddfea7b4b3aee1a 295 Pfam PF00849 RNA pseudouridylate synthase 87 241 2.5E-20 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CFK41_RS12605 d26e95287bbd49e1cddfea7b4b3aee1a 295 SUPERFAMILY SSF55120 74 288 6.56E-43 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CFK41_RS12605 d26e95287bbd49e1cddfea7b4b3aee1a 295 Gene3D G3DSA:3.30.2350.10 79 294 6.2E-41 T 28-03-2018 CFK41_RS10325 a2bc1aec0b612ca7a8b6527657bb92c8 258 Pfam PF00557 Metallopeptidase family M24 14 246 6.6E-35 T 28-03-2018 IPR000994 Peptidase M24 CFK41_RS10325 a2bc1aec0b612ca7a8b6527657bb92c8 258 Hamap MF_01974 Methionine aminopeptidase [map]. 2 255 30.24 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CFK41_RS10325 a2bc1aec0b612ca7a8b6527657bb92c8 258 PRINTS PR00599 Methionine aminopeptidase-1 signature 166 178 8.0E-14 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CFK41_RS10325 a2bc1aec0b612ca7a8b6527657bb92c8 258 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 8.0E-14 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CFK41_RS10325 a2bc1aec0b612ca7a8b6527657bb92c8 258 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 8.0E-14 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CFK41_RS10325 a2bc1aec0b612ca7a8b6527657bb92c8 258 PRINTS PR00599 Methionine aminopeptidase-1 signature 197 209 8.0E-14 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CFK41_RS10325 a2bc1aec0b612ca7a8b6527657bb92c8 258 SUPERFAMILY SSF55920 1 256 1.57E-60 T 28-03-2018 IPR000994 Peptidase M24 CFK41_RS10325 a2bc1aec0b612ca7a8b6527657bb92c8 258 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 254 1.3E-62 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CFK41_RS10325 a2bc1aec0b612ca7a8b6527657bb92c8 258 Gene3D G3DSA:3.90.230.10 1 256 5.4E-57 T 28-03-2018 CFK41_RS09270 e519914d1fa7378dc2fea07b377e51cc 148 Gene3D G3DSA:1.10.440.10 1 116 2.3E-6 T 28-03-2018 IPR024796 T4 endonuclease V CFK41_RS08865 6a16104f37c556f2ba56ae4854dd8683 343 SUPERFAMILY SSF50129 1 175 2.28E-48 T 28-03-2018 IPR011032 GroES-like CFK41_RS08865 6a16104f37c556f2ba56ae4854dd8683 343 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CFK41_RS08865 6a16104f37c556f2ba56ae4854dd8683 343 Gene3D G3DSA:3.90.180.10 1 149 1.2E-39 T 28-03-2018 CFK41_RS08865 6a16104f37c556f2ba56ae4854dd8683 343 SMART SM00829 9 335 8.8E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CFK41_RS08865 6a16104f37c556f2ba56ae4854dd8683 343 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 135 7.8E-25 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CFK41_RS08865 6a16104f37c556f2ba56ae4854dd8683 343 Pfam PF00107 Zinc-binding dehydrogenase 177 303 3.5E-18 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CFK41_RS08865 6a16104f37c556f2ba56ae4854dd8683 343 Gene3D G3DSA:3.40.50.720 150 332 7.1E-28 T 28-03-2018 CFK41_RS08865 6a16104f37c556f2ba56ae4854dd8683 343 SUPERFAMILY SSF51735 140 307 1.36E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS01060 b376ca47464219b40d28e7ee6a13c2ce 232 SUPERFAMILY SSF161098 9 196 1.19E-39 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01060 b376ca47464219b40d28e7ee6a13c2ce 232 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 210 5.3E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01060 b376ca47464219b40d28e7ee6a13c2ce 232 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 7 105 2.4E-27 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CFK41_RS01060 b376ca47464219b40d28e7ee6a13c2ce 232 Gene3D G3DSA:1.10.3720.10 2 216 1.9E-36 T 28-03-2018 CFK41_RS16195 4000b23aa5954a6e8d6cfb9acdf80425 1031 SUPERFAMILY SSF58104 519 721 6.28E-6 T 28-03-2018 CFK41_RS16195 4000b23aa5954a6e8d6cfb9acdf80425 1031 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 232 259 2.6E-7 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CFK41_RS16195 4000b23aa5954a6e8d6cfb9acdf80425 1031 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 738 765 2.7E-4 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CFK41_RS16195 4000b23aa5954a6e8d6cfb9acdf80425 1031 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 239 266 3.2E-7 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CFK41_RS16195 4000b23aa5954a6e8d6cfb9acdf80425 1031 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 255 280 4.6E-6 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CFK41_RS16195 4000b23aa5954a6e8d6cfb9acdf80425 1031 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 338 362 1.8E-4 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CFK41_RS16195 4000b23aa5954a6e8d6cfb9acdf80425 1031 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 766 793 3.0E-8 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CFK41_RS16195 4000b23aa5954a6e8d6cfb9acdf80425 1031 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 327 350 2.6E-4 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CFK41_RS16195 4000b23aa5954a6e8d6cfb9acdf80425 1031 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 289 315 7.4E-5 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CFK41_RS16195 4000b23aa5954a6e8d6cfb9acdf80425 1031 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 220 245 1.4E-5 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CFK41_RS16195 4000b23aa5954a6e8d6cfb9acdf80425 1031 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 711 737 3.5E-6 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CFK41_RS16195 4000b23aa5954a6e8d6cfb9acdf80425 1031 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 683 709 7.9E-5 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CFK41_RS16195 4000b23aa5954a6e8d6cfb9acdf80425 1031 Pfam PF12698 ABC-2 family transporter protein 826 1011 9.8E-12 T 28-03-2018 CFK41_RS16195 4000b23aa5954a6e8d6cfb9acdf80425 1031 Gene3D G3DSA:1.10.287.950 620 717 7.4E-10 T 28-03-2018 CFK41_RS16195 4000b23aa5954a6e8d6cfb9acdf80425 1031 Gene3D G3DSA:3.40.1710.10 77 244 3.3E-18 T 28-03-2018 CFK41_RS16195 4000b23aa5954a6e8d6cfb9acdf80425 1031 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 49 215 2.2E-32 T 28-03-2018 IPR017500 Phage infection protein, YhgE, N-terminal CFK41_RS16195 4000b23aa5954a6e8d6cfb9acdf80425 1031 Gene3D G3DSA:1.10.287.950 718 805 7.0E-11 T 28-03-2018 CFK41_RS16195 4000b23aa5954a6e8d6cfb9acdf80425 1031 Gene3D G3DSA:1.10.287.950 287 370 8.1E-6 T 28-03-2018 CFK41_RS16195 4000b23aa5954a6e8d6cfb9acdf80425 1031 Gene3D G3DSA:1.20.120.570 513 619 0.0026 T 28-03-2018 CFK41_RS16195 4000b23aa5954a6e8d6cfb9acdf80425 1031 Gene3D G3DSA:1.20.120.570 371 507 1.3E-4 T 28-03-2018 CFK41_RS16195 4000b23aa5954a6e8d6cfb9acdf80425 1031 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 815 1014 3.9E-52 T 28-03-2018 IPR017501 Phage infection protein, YhgE, C-terminal CFK41_RS08060 31707629db596ae858baf6a3b9561f68 282 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 218 281 4.5E-18 T 28-03-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain CFK41_RS08060 31707629db596ae858baf6a3b9561f68 282 Pfam PF10531 SLBB domain 135 189 8.4E-15 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CFK41_RS08060 31707629db596ae858baf6a3b9561f68 282 Gene3D G3DSA:1.10.150.280 227 282 8.1E-20 T 28-03-2018 CFK41_RS08060 31707629db596ae858baf6a3b9561f68 282 Gene3D G3DSA:3.10.560.10 124 226 3.7E-13 T 28-03-2018 CFK41_RS08060 31707629db596ae858baf6a3b9561f68 282 Pfam PF12836 Helix-hairpin-helix motif 220 279 8.8E-24 T 28-03-2018 CFK41_RS08060 31707629db596ae858baf6a3b9561f68 282 SUPERFAMILY SSF47781 214 282 4.45E-28 T 28-03-2018 IPR010994 RuvA domain 2-like CFK41_RS08060 31707629db596ae858baf6a3b9561f68 282 SMART SM00278 230 249 0.0022 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CFK41_RS08060 31707629db596ae858baf6a3b9561f68 282 SMART SM00278 260 279 200.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CFK41_RS08660 7050a18d7812b213fcd265a4374bf8ad 485 Pfam PF03136 Pup-ligase protein 4 440 1.8E-137 T 28-03-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 CFK41_RS08660 7050a18d7812b213fcd265a4374bf8ad 485 TIGRFAM TIGR03686 pupylate_PafA: Pup--protein ligase 3 469 2.2E-173 T 28-03-2018 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 CFK41_RS08660 7050a18d7812b213fcd265a4374bf8ad 485 Hamap MF_02111 Pup--protein ligase [pafA]. 1 470 46.007 T 28-03-2018 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 CFK41_RS17350 0e558a0ac008cf8c72b7ac937cb330a5 399 Gene3D G3DSA:2.60.40.10 307 394 0.064 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS17350 0e558a0ac008cf8c72b7ac937cb330a5 399 Gene3D G3DSA:2.60.40.10 211 306 0.028 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS10560 e57519cae80ce4f23d1c6363828e1273 481 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 1.3E-23 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CFK41_RS10560 e57519cae80ce4f23d1c6363828e1273 481 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 1.3E-23 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CFK41_RS10560 e57519cae80ce4f23d1c6363828e1273 481 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 194 212 1.3E-23 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CFK41_RS10560 e57519cae80ce4f23d1c6363828e1273 481 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 225 246 1.3E-23 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CFK41_RS10560 e57519cae80ce4f23d1c6363828e1273 481 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 17 315 4.1E-107 T 28-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 CFK41_RS10560 e57519cae80ce4f23d1c6363828e1273 481 SMART SM00840 352 416 8.5E-11 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CFK41_RS10560 e57519cae80ce4f23d1c6363828e1273 481 Gene3D G3DSA:3.40.50.620 1 307 1.4E-76 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS10560 e57519cae80ce4f23d1c6363828e1273 481 Gene3D G3DSA:1.20.120.640 308 407 8.8E-15 T 28-03-2018 CFK41_RS10560 e57519cae80ce4f23d1c6363828e1273 481 SUPERFAMILY SSF52374 4 314 8.58E-77 T 28-03-2018 CFK41_RS10560 e57519cae80ce4f23d1c6363828e1273 481 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 476 7.0E-126 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CFK41_RS10560 e57519cae80ce4f23d1c6363828e1273 481 Pfam PF09190 DALR domain 352 408 7.0E-8 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CFK41_RS10560 e57519cae80ce4f23d1c6363828e1273 481 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 478 33.747 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CFK41_RS10560 e57519cae80ce4f23d1c6363828e1273 481 SUPERFAMILY SSF47323 344 477 4.71E-29 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS12305 974d9e577607fa2b8957e053fce9cbe8 105 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 4 60 1.5E-8 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CFK41_RS12305 974d9e577607fa2b8957e053fce9cbe8 105 Gene3D G3DSA:3.40.50.2300 1 97 2.4E-17 T 28-03-2018 CFK41_RS12305 974d9e577607fa2b8957e053fce9cbe8 105 SUPERFAMILY SSF52794 1 78 1.05E-12 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CFK41_RS00520 28e38fa974fa416c99990e2b278bcda1 215 Pfam PF00395 S-layer homology domain 25 68 1.3E-5 T 28-03-2018 IPR001119 S-layer homology domain CFK41_RS10925 fd604030ac373438202a55bd505e37e0 505 Gene3D G3DSA:1.10.4100.10 7 331 7.1E-87 T 28-03-2018 CFK41_RS10925 fd604030ac373438202a55bd505e37e0 505 SUPERFAMILY SSF103378 18 483 7.45E-126 T 28-03-2018 IPR005656 MmgE/PrpD GO:0016829 CFK41_RS10925 fd604030ac373438202a55bd505e37e0 505 Pfam PF03972 MmgE/PrpD family 20 474 1.8E-129 T 28-03-2018 IPR005656 MmgE/PrpD GO:0016829 CFK41_RS10200 8134435e501b5364f79ac0fee0567106 229 SUPERFAMILY SSF101386 2 95 4.11E-17 T 28-03-2018 CFK41_RS10200 8134435e501b5364f79ac0fee0567106 229 Gene3D G3DSA:1.10.287.1080 144 220 0.021 T 28-03-2018 CFK41_RS10200 8134435e501b5364f79ac0fee0567106 229 Gene3D G3DSA:1.10.287.1080 1 121 6.5E-28 T 28-03-2018 CFK41_RS10200 8134435e501b5364f79ac0fee0567106 229 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 16 93 9.3E-22 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CFK41_RS06835 32c8316b9c61958cc05772f897be637a 209 SUPERFAMILY SSF54719 84 198 5.63E-43 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CFK41_RS06835 32c8316b9c61958cc05772f897be637a 209 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 160 167 - T 28-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CFK41_RS06835 32c8316b9c61958cc05772f897be637a 209 PIRSF PIRSF000349 1 202 3.0E-75 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CFK41_RS06835 32c8316b9c61958cc05772f897be637a 209 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 1.3E-21 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CFK41_RS06835 32c8316b9c61958cc05772f897be637a 209 PRINTS PR01703 Manganese superoxide dismutase signature 158 170 1.3E-21 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CFK41_RS06835 32c8316b9c61958cc05772f897be637a 209 PRINTS PR01703 Manganese superoxide dismutase signature 120 128 1.3E-21 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CFK41_RS06835 32c8316b9c61958cc05772f897be637a 209 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 1.3E-21 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CFK41_RS06835 32c8316b9c61958cc05772f897be637a 209 PRINTS PR01703 Manganese superoxide dismutase signature 67 80 1.3E-21 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CFK41_RS06835 32c8316b9c61958cc05772f897be637a 209 Gene3D G3DSA:1.10.287.990 21 84 7.7E-22 T 28-03-2018 CFK41_RS06835 32c8316b9c61958cc05772f897be637a 209 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 84 1.9E-31 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CFK41_RS06835 32c8316b9c61958cc05772f897be637a 209 SUPERFAMILY SSF46609 3 88 4.06E-32 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CFK41_RS06835 32c8316b9c61958cc05772f897be637a 209 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 91 193 1.8E-34 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CFK41_RS11490 7bde6a40f1213cbf9bfe63be7f973b5a 362 Gene3D G3DSA:3.40.50.2000 174 353 2.1E-36 T 28-03-2018 CFK41_RS11490 7bde6a40f1213cbf9bfe63be7f973b5a 362 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 193 350 3.9E-33 T 28-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CFK41_RS11490 7bde6a40f1213cbf9bfe63be7f973b5a 362 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 1 354 1.6E-78 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CFK41_RS11490 7bde6a40f1213cbf9bfe63be7f973b5a 362 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 8 359 29.904 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CFK41_RS11490 7bde6a40f1213cbf9bfe63be7f973b5a 362 Gene3D G3DSA:3.40.50.2000 1 173 2.6E-34 T 28-03-2018 CFK41_RS11490 7bde6a40f1213cbf9bfe63be7f973b5a 362 SUPERFAMILY SSF53756 7 360 3.59E-92 T 28-03-2018 CFK41_RS11490 7bde6a40f1213cbf9bfe63be7f973b5a 362 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 8 147 5.6E-31 T 28-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CFK41_RS05270 b23670343d71e59ce55bad186787bf46 538 Gene3D G3DSA:3.60.21.10 159 538 1.4E-35 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CFK41_RS05270 b23670343d71e59ce55bad186787bf46 538 SUPERFAMILY SSF56300 157 536 2.62E-36 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CFK41_RS05270 b23670343d71e59ce55bad186787bf46 538 Pfam PF09423 PhoD-like phosphatase 168 480 5.3E-75 T 28-03-2018 IPR018946 Alkaline phosphatase D-related CFK41_RS13790 958bf0d352491c954b47252eb123ee61 346 Gene3D G3DSA:3.40.630.30 166 337 1.7E-10 T 28-03-2018 CFK41_RS13790 958bf0d352491c954b47252eb123ee61 346 SUPERFAMILY SSF55729 210 333 3.01E-10 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS13790 958bf0d352491c954b47252eb123ee61 346 SUPERFAMILY SSF55729 1 111 1.29E-12 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS13790 958bf0d352491c954b47252eb123ee61 346 Pfam PF00583 Acetyltransferase (GNAT) family 56 111 1.1E-4 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS13790 958bf0d352491c954b47252eb123ee61 346 Gene3D G3DSA:3.40.630.30 97 154 7.2E-6 T 28-03-2018 CFK41_RS13790 958bf0d352491c954b47252eb123ee61 346 Gene3D G3DSA:3.40.630.30 1 96 9.3E-6 T 28-03-2018 CFK41_RS00170 5f12784e3aa47910c2cd995380fb9df3 310 Pfam PF01636 Phosphotransferase enzyme family 57 261 4.0E-28 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CFK41_RS00170 5f12784e3aa47910c2cd995380fb9df3 310 Gene3D G3DSA:1.10.510.10 62 298 7.9E-21 T 28-03-2018 CFK41_RS00170 5f12784e3aa47910c2cd995380fb9df3 310 SUPERFAMILY SSF56112 18 268 8.16E-32 T 28-03-2018 IPR011009 Protein kinase-like domain CFK41_RS07175 2e35b6ee59a3647616b0e89d879db0eb 739 Gene3D G3DSA:1.10.10.10 379 568 3.9E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS07175 2e35b6ee59a3647616b0e89d879db0eb 739 Gene3D G3DSA:3.40.50.300 13 232 1.2E-26 T 28-03-2018 CFK41_RS07175 2e35b6ee59a3647616b0e89d879db0eb 739 SMART SM00487 31 237 5.5E-24 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CFK41_RS07175 2e35b6ee59a3647616b0e89d879db0eb 739 SMART SM00490 273 354 2.1E-21 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS07175 2e35b6ee59a3647616b0e89d879db0eb 739 Gene3D G3DSA:3.40.50.2020 598 739 7.0E-13 T 28-03-2018 CFK41_RS07175 2e35b6ee59a3647616b0e89d879db0eb 739 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 34 369 1.0E-65 T 28-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CFK41_RS07175 2e35b6ee59a3647616b0e89d879db0eb 739 SUPERFAMILY SSF53271 606 736 1.61E-8 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CFK41_RS07175 2e35b6ee59a3647616b0e89d879db0eb 739 Pfam PF00271 Helicase conserved C-terminal domain 250 353 4.1E-14 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS07175 2e35b6ee59a3647616b0e89d879db0eb 739 Pfam PF00270 DEAD/DEAH box helicase 38 207 8.8E-19 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CFK41_RS07175 2e35b6ee59a3647616b0e89d879db0eb 739 SUPERFAMILY SSF52540 79 373 3.98E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS07175 2e35b6ee59a3647616b0e89d879db0eb 739 Gene3D G3DSA:3.40.50.300 238 378 1.2E-26 T 28-03-2018 CFK41_RS01090 5f58d7a2900695ef1e5fe8e1278565bf 319 Gene3D G3DSA:3.40.190.10 202 319 4.4E-15 T 28-03-2018 CFK41_RS01090 5f58d7a2900695ef1e5fe8e1278565bf 319 SUPERFAMILY SSF53850 57 318 1.68E-43 T 28-03-2018 CFK41_RS01090 5f58d7a2900695ef1e5fe8e1278565bf 319 Gene3D G3DSA:3.40.190.10 44 201 2.2E-25 T 28-03-2018 CFK41_RS01090 5f58d7a2900695ef1e5fe8e1278565bf 319 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 56 315 6.9E-43 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CFK41_RS08915 d6713964ef2538b5bb0b45f34cc36a29 256 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 33 237 4.4E-26 T 28-03-2018 IPR003744 Queuosine precursor transporter CFK41_RS08915 d6713964ef2538b5bb0b45f34cc36a29 256 Pfam PF02592 Putative vitamin uptake transporter 68 231 1.6E-38 T 28-03-2018 IPR003744 Queuosine precursor transporter CFK41_RS03640 409171c578b6cb11fdd6b9a00a67f31d 471 Gene3D G3DSA:1.10.275.10 9 123 8.7E-34 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CFK41_RS03640 409171c578b6cb11fdd6b9a00a67f31d 471 PRINTS PR00149 Fumarate lyase superfamily signature 255 282 2.0E-16 T 28-03-2018 IPR000362 Fumarate lyase family CFK41_RS03640 409171c578b6cb11fdd6b9a00a67f31d 471 PRINTS PR00149 Fumarate lyase superfamily signature 167 185 2.0E-16 T 28-03-2018 IPR000362 Fumarate lyase family CFK41_RS03640 409171c578b6cb11fdd6b9a00a67f31d 471 PRINTS PR00149 Fumarate lyase superfamily signature 121 139 2.0E-16 T 28-03-2018 IPR000362 Fumarate lyase family CFK41_RS03640 409171c578b6cb11fdd6b9a00a67f31d 471 PRINTS PR00149 Fumarate lyase superfamily signature 299 315 2.0E-16 T 28-03-2018 IPR000362 Fumarate lyase family CFK41_RS03640 409171c578b6cb11fdd6b9a00a67f31d 471 Pfam PF08328 Adenylosuccinate lyase C-terminal 336 456 3.6E-41 T 28-03-2018 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 CFK41_RS03640 409171c578b6cb11fdd6b9a00a67f31d 471 SUPERFAMILY SSF48557 15 464 1.1E-88 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CFK41_RS03640 409171c578b6cb11fdd6b9a00a67f31d 471 ProSitePatterns PS00163 Fumarate lyases signature. 299 308 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CFK41_RS03640 409171c578b6cb11fdd6b9a00a67f31d 471 Pfam PF00206 Lyase 19 315 2.7E-46 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CFK41_RS03640 409171c578b6cb11fdd6b9a00a67f31d 471 Gene3D G3DSA:1.10.40.30 395 456 2.7E-23 T 28-03-2018 CFK41_RS03640 409171c578b6cb11fdd6b9a00a67f31d 471 Gene3D G3DSA:1.20.200.10 124 394 9.7E-73 T 28-03-2018 CFK41_RS09510 b9f5b2290b6312d74ca31d9c03a5bbcf 108 PIRSF PIRSF002134 42 108 6.6E-6 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS09510 b9f5b2290b6312d74ca31d9c03a5bbcf 108 Gene3D G3DSA:1.10.8.50 72 108 4.7E-4 T 28-03-2018 CFK41_RS09510 b9f5b2290b6312d74ca31d9c03a5bbcf 108 Gene3D G3DSA:1.10.150.20 9 71 0.0014 T 28-03-2018 CFK41_RS09510 b9f5b2290b6312d74ca31d9c03a5bbcf 108 SUPERFAMILY SSF46946 60 106 4.71E-8 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CFK41_RS05585 ef57532b235fef924d30b4a8d6507484 742 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 1 738 0.0 T 28-03-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CFK41_RS05585 ef57532b235fef924d30b4a8d6507484 742 Gene3D G3DSA:3.40.718.10 413 710 1.5E-41 T 28-03-2018 CFK41_RS05585 ef57532b235fef924d30b4a8d6507484 742 Gene3D G3DSA:3.40.718.10 17 408 8.7E-41 T 28-03-2018 CFK41_RS05585 ef57532b235fef924d30b4a8d6507484 742 Pfam PF03971 Monomeric isocitrate dehydrogenase 3 736 0.0 T 28-03-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CFK41_RS05585 ef57532b235fef924d30b4a8d6507484 742 SUPERFAMILY SSF53659 3 738 0.0 T 28-03-2018 CFK41_RS05585 ef57532b235fef924d30b4a8d6507484 742 PIRSF PIRSF009407 1 739 0.0 T 28-03-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CFK41_RS01600 0d01252439d2300729fda9176811d80d 456 Gene3D G3DSA:3.40.190.10 183 451 1.9E-24 T 28-03-2018 CFK41_RS01600 0d01252439d2300729fda9176811d80d 456 SUPERFAMILY SSF53850 54 446 1.6E-41 T 28-03-2018 CFK41_RS01600 0d01252439d2300729fda9176811d80d 456 Gene3D G3DSA:3.40.190.10 56 182 3.8E-12 T 28-03-2018 CFK41_RS01600 0d01252439d2300729fda9176811d80d 456 Pfam PF13416 Bacterial extracellular solute-binding protein 77 380 1.2E-17 T 28-03-2018 CFK41_RS12670 2eb6b7adfe69ada23c674f97b159af55 343 Gene3D G3DSA:1.10.3720.10 4 331 1.1E-31 T 28-03-2018 CFK41_RS12670 2eb6b7adfe69ada23c674f97b159af55 343 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 134 342 1.7E-33 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS12670 2eb6b7adfe69ada23c674f97b159af55 343 SUPERFAMILY SSF161098 113 325 2.4E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS00555 20dc9cf82da971ccc8c13a639d30888a 553 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 47 533 3.8E-161 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CFK41_RS00555 20dc9cf82da971ccc8c13a639d30888a 553 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 85 533 3.8E-133 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CFK41_RS14190 b2e6b2ddf0ee1ef86393bce107b82d45 576 Pfam PF01229 Glycosyl hydrolases family 39 107 572 1.1E-49 T 28-03-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101 CFK41_RS14190 b2e6b2ddf0ee1ef86393bce107b82d45 576 SUPERFAMILY SSF51445 107 424 5.73E-48 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS14190 b2e6b2ddf0ee1ef86393bce107b82d45 576 Gene3D G3DSA:3.20.20.80 68 418 6.3E-30 T 28-03-2018 CFK41_RS14190 b2e6b2ddf0ee1ef86393bce107b82d45 576 PRINTS PR00745 Glycosyl hydrolase family 39 signature 126 142 5.0E-7 T 28-03-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101 CFK41_RS14190 b2e6b2ddf0ee1ef86393bce107b82d45 576 PRINTS PR00745 Glycosyl hydrolase family 39 signature 516 530 5.0E-7 T 28-03-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101 CFK41_RS14190 b2e6b2ddf0ee1ef86393bce107b82d45 576 PRINTS PR00745 Glycosyl hydrolase family 39 signature 505 516 5.0E-7 T 28-03-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101 CFK41_RS14190 b2e6b2ddf0ee1ef86393bce107b82d45 576 PRINTS PR00745 Glycosyl hydrolase family 39 signature 264 278 5.0E-7 T 28-03-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101 CFK41_RS14190 b2e6b2ddf0ee1ef86393bce107b82d45 576 SUPERFAMILY SSF51011 439 574 4.68E-22 T 28-03-2018 CFK41_RS14190 b2e6b2ddf0ee1ef86393bce107b82d45 576 Gene3D G3DSA:2.60.40.1500 419 576 7.9E-37 T 28-03-2018 CFK41_RS10535 4e62db6150f7ecb37a6a507166b6436b 233 Pfam PF01327 Polypeptide deformylase 27 190 8.5E-31 T 28-03-2018 IPR023635 Peptide deformylase CFK41_RS10535 4e62db6150f7ecb37a6a507166b6436b 233 Hamap MF_00163 Peptide deformylase [def]. 25 205 20.641 T 28-03-2018 IPR023635 Peptide deformylase CFK41_RS10535 4e62db6150f7ecb37a6a507166b6436b 233 Gene3D G3DSA:3.90.45.10 9 201 6.5E-43 T 28-03-2018 IPR023635 Peptide deformylase CFK41_RS10535 4e62db6150f7ecb37a6a507166b6436b 233 PRINTS PR01576 Peptide deformylase signature 130 141 3.3E-20 T 28-03-2018 IPR023635 Peptide deformylase CFK41_RS10535 4e62db6150f7ecb37a6a507166b6436b 233 PRINTS PR01576 Peptide deformylase signature 58 87 3.3E-20 T 28-03-2018 IPR023635 Peptide deformylase CFK41_RS10535 4e62db6150f7ecb37a6a507166b6436b 233 PRINTS PR01576 Peptide deformylase signature 165 194 3.3E-20 T 28-03-2018 IPR023635 Peptide deformylase CFK41_RS10535 4e62db6150f7ecb37a6a507166b6436b 233 SUPERFAMILY SSF56420 26 191 4.06E-35 T 28-03-2018 IPR023635 Peptide deformylase CFK41_RS01865 e4773ece79cc1e39544c095f88e8d9a9 406 ProSitePatterns PS00216 Sugar transport proteins signature 1. 71 87 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CFK41_RS01865 e4773ece79cc1e39544c095f88e8d9a9 406 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 16 383 3.6E-85 T 28-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 CFK41_RS01865 e4773ece79cc1e39544c095f88e8d9a9 406 Gene3D G3DSA:1.20.1250.20 12 202 1.1E-26 T 28-03-2018 CFK41_RS01865 e4773ece79cc1e39544c095f88e8d9a9 406 Pfam PF07690 Major Facilitator Superfamily 21 365 8.8E-46 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS01865 e4773ece79cc1e39544c095f88e8d9a9 406 Gene3D G3DSA:1.20.1250.20 208 405 1.3E-15 T 28-03-2018 CFK41_RS01865 e4773ece79cc1e39544c095f88e8d9a9 406 SUPERFAMILY SSF103473 6 399 9.81E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS01865 e4773ece79cc1e39544c095f88e8d9a9 406 PRINTS PR01035 Tetracycline resistance protein signature 27 43 1.0E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CFK41_RS01865 e4773ece79cc1e39544c095f88e8d9a9 406 PRINTS PR01035 Tetracycline resistance protein signature 84 108 1.0E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CFK41_RS01865 e4773ece79cc1e39544c095f88e8d9a9 406 PRINTS PR01035 Tetracycline resistance protein signature 142 164 1.0E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CFK41_RS05455 1ef7190fe1d547dc0a8809ee19d515eb 348 SUPERFAMILY SSF81345 16 342 9.02E-74 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CFK41_RS05455 1ef7190fe1d547dc0a8809ee19d515eb 348 Pfam PF01032 FecCD transport family 35 342 4.1E-80 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CFK41_RS05455 1ef7190fe1d547dc0a8809ee19d515eb 348 Gene3D G3DSA:1.10.3470.10 18 348 3.1E-58 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CFK41_RS05955 28deeb430eda78df72c3a276b7b448f1 149 PIRSF PIRSF018072 1 149 1.0E-46 T 28-03-2018 IPR016709 Uncharacterised protein family UPF0336 CFK41_RS05955 28deeb430eda78df72c3a276b7b448f1 149 Gene3D G3DSA:3.10.129.10 6 149 5.3E-36 T 28-03-2018 CFK41_RS05955 28deeb430eda78df72c3a276b7b448f1 149 SUPERFAMILY SSF54637 10 149 9.13E-35 T 28-03-2018 IPR029069 HotDog domain CFK41_RS05955 28deeb430eda78df72c3a276b7b448f1 149 Pfam PF13452 N-terminal half of MaoC dehydratase 20 138 7.4E-26 T 28-03-2018 CFK41_RS03490 a81cb69ae5d9db282ab83c666e08a223 66 Pfam PF14029 Protein of unknown function (DUF4244) 12 63 2.6E-21 T 28-03-2018 IPR025338 Protein of unknown function DUF4244 CFK41_RS05280 a859044f4e5d75dc86df48abfdf5446c 261 Pfam PF00005 ABC transporter 35 184 1.9E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS05280 a859044f4e5d75dc86df48abfdf5446c 261 SUPERFAMILY SSF52540 19 254 5.82E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS05280 a859044f4e5d75dc86df48abfdf5446c 261 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS05280 a859044f4e5d75dc86df48abfdf5446c 261 SMART SM00382 44 232 2.4E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS05280 a859044f4e5d75dc86df48abfdf5446c 261 PIRSF PIRSF039085 16 260 7.0E-107 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CFK41_RS05280 a859044f4e5d75dc86df48abfdf5446c 261 Gene3D G3DSA:3.40.50.300 15 259 2.2E-72 T 28-03-2018 CFK41_RS05790 921c13ada4c8612e2f5337b567aa1fc6 389 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 2 388 4.7E-105 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CFK41_RS05790 921c13ada4c8612e2f5337b567aa1fc6 389 SUPERFAMILY SSF56266 6 385 2.75E-121 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CFK41_RS05790 921c13ada4c8612e2f5337b567aa1fc6 389 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 17 387 2.0E-100 T 28-03-2018 CFK41_RS05790 921c13ada4c8612e2f5337b567aa1fc6 389 Pfam PF01960 ArgJ family 11 389 3.5E-126 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CFK41_RS05790 921c13ada4c8612e2f5337b567aa1fc6 389 Gene3D G3DSA:3.60.70.12 1 262 8.5E-93 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CFK41_RS05790 921c13ada4c8612e2f5337b567aa1fc6 389 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 389 126.549 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CFK41_RS15725 f94a7e18fc4ad37c39fa0d26b5bc76df 586 Gene3D G3DSA:1.25.40.10 190 462 7.6E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CFK41_RS11445 efacad5d51fdf1c33339b049e7a42fd7 308 Gene3D G3DSA:3.10.290.10 2 72 7.6E-14 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CFK41_RS11445 efacad5d51fdf1c33339b049e7a42fd7 308 Pfam PF00849 RNA pseudouridylate synthase 90 244 1.8E-31 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CFK41_RS11445 efacad5d51fdf1c33339b049e7a42fd7 308 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 14 306 3.8E-83 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CFK41_RS11445 efacad5d51fdf1c33339b049e7a42fd7 308 Gene3D G3DSA:3.30.2350.10 81 308 2.1E-64 T 28-03-2018 CFK41_RS11445 efacad5d51fdf1c33339b049e7a42fd7 308 SUPERFAMILY SSF55174 13 105 1.77E-9 T 28-03-2018 CFK41_RS11445 efacad5d51fdf1c33339b049e7a42fd7 308 SMART SM00363 16 78 2.6E-5 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CFK41_RS11445 efacad5d51fdf1c33339b049e7a42fd7 308 Pfam PF01479 S4 domain 16 60 6.8E-6 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CFK41_RS11445 efacad5d51fdf1c33339b049e7a42fd7 308 SUPERFAMILY SSF55120 79 306 1.67E-67 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CFK41_RS17255 a538ef3fe36ebcb13bb8f66196553d62 164 Pfam PF12724 Flavodoxin domain 4 147 4.7E-26 T 28-03-2018 IPR026816 Flavodoxin domain CFK41_RS17255 a538ef3fe36ebcb13bb8f66196553d62 164 SUPERFAMILY SSF52218 1 162 1.19E-17 T 28-03-2018 IPR029039 Flavoprotein-like domain CFK41_RS17255 a538ef3fe36ebcb13bb8f66196553d62 164 Gene3D G3DSA:3.40.50.360 1 164 9.9E-19 T 28-03-2018 IPR029039 Flavoprotein-like domain CFK41_RS06445 ae014f08d7e101f00a5ab93cf985a6cd 248 SUPERFAMILY SSF143081 2 239 4.58E-58 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) CFK41_RS06445 ae014f08d7e101f00a5ab93cf985a6cd 248 Gene3D G3DSA:3.90.1680.10 1 246 4.7E-66 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) CFK41_RS06445 ae014f08d7e101f00a5ab93cf985a6cd 248 Pfam PF02586 SOS response associated peptidase (SRAP) 1 233 3.7E-57 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) CFK41_RS00020 132583f818e8b2faff51db7e222dcac7 548 Pfam PF13320 Domain of unknown function (DUF4091) 429 499 5.7E-16 T 28-03-2018 IPR025150 Domain of unknown function DUF4091 CFK41_RS00020 132583f818e8b2faff51db7e222dcac7 548 Gene3D G3DSA:3.20.20.80 166 504 2.9E-5 T 28-03-2018 CFK41_RS14275 882518406c0578136851353649ad87e8 512 Gene3D G3DSA:3.40.190.10 167 510 3.0E-23 T 28-03-2018 CFK41_RS14275 882518406c0578136851353649ad87e8 512 Gene3D G3DSA:3.40.190.10 19 166 9.0E-12 T 28-03-2018 CFK41_RS14275 882518406c0578136851353649ad87e8 512 SUPERFAMILY SSF53850 30 507 3.39E-54 T 28-03-2018 CFK41_RS14275 882518406c0578136851353649ad87e8 512 Pfam PF13416 Bacterial extracellular solute-binding protein 39 322 6.2E-15 T 28-03-2018 CFK41_RS04400 663ee48a125e7065ffafaafbae0edb13 570 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 21 569 27.941 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CFK41_RS04400 663ee48a125e7065ffafaafbae0edb13 570 Gene3D G3DSA:3.40.50.970 24 218 1.6E-49 T 28-03-2018 CFK41_RS04400 663ee48a125e7065ffafaafbae0edb13 570 PIRSF PIRSF004983 23 568 9.4E-115 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CFK41_RS04400 663ee48a125e7065ffafaafbae0edb13 570 SUPERFAMILY SSF52518 388 547 7.0E-13 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CFK41_RS04400 663ee48a125e7065ffafaafbae0edb13 570 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 30 448 8.4E-99 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CFK41_RS04400 663ee48a125e7065ffafaafbae0edb13 570 SUPERFAMILY SSF52518 30 209 2.08E-30 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CFK41_RS04400 663ee48a125e7065ffafaafbae0edb13 570 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 30 198 2.8E-28 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CFK41_RS04400 663ee48a125e7065ffafaafbae0edb13 570 Gene3D G3DSA:3.40.50.970 387 556 3.3E-13 T 28-03-2018 CFK41_RS04400 663ee48a125e7065ffafaafbae0edb13 570 Gene3D G3DSA:3.40.50.1220 240 386 5.8E-14 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CFK41_RS00590 2c2260f5e6e48b4a371287dcef0435d4 246 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 18 234 3.3E-33 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CFK41_RS00590 2c2260f5e6e48b4a371287dcef0435d4 246 SUPERFAMILY SSF51695 12 237 2.07E-56 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CFK41_RS00590 2c2260f5e6e48b4a371287dcef0435d4 246 Gene3D G3DSA:3.20.20.190 1 242 2.3E-56 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CFK41_RS13570 afb7b739a14a82492e5410138a84ffa8 308 PIRSF PIRSF028188 1 304 3.1E-107 T 28-03-2018 IPR014541 Predicted amidinotransferase, FN0238 type CFK41_RS13570 afb7b739a14a82492e5410138a84ffa8 308 Gene3D G3DSA:3.75.10.10 4 300 5.2E-39 T 28-03-2018 CFK41_RS13570 afb7b739a14a82492e5410138a84ffa8 308 SUPERFAMILY SSF55909 8 300 2.35E-35 T 28-03-2018 CFK41_RS13570 afb7b739a14a82492e5410138a84ffa8 308 Pfam PF02274 Amidinotransferase 11 300 1.2E-63 T 28-03-2018 CFK41_RS10745 d8b07a0acd03e55ce82d7cff2139de45 123 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 2 122 36.784 T 28-03-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CFK41_RS10745 d8b07a0acd03e55ce82d7cff2139de45 123 SUPERFAMILY SSF51230 3 122 9.55E-40 T 28-03-2018 IPR011053 Single hybrid motif CFK41_RS10745 d8b07a0acd03e55ce82d7cff2139de45 123 Gene3D G3DSA:2.40.50.100 3 123 3.5E-42 T 28-03-2018 CFK41_RS10745 d8b07a0acd03e55ce82d7cff2139de45 123 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 122 2.1E-46 T 28-03-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CFK41_RS10745 d8b07a0acd03e55ce82d7cff2139de45 123 Pfam PF01597 Glycine cleavage H-protein 5 122 7.3E-43 T 28-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate CFK41_RS10745 d8b07a0acd03e55ce82d7cff2139de45 123 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 46 75 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CFK41_RS10405 bf3db9ef4870387892edaa21808e202e 317 SUPERFAMILY SSF161098 27 317 5.74E-55 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS10405 bf3db9ef4870387892edaa21808e202e 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 131 310 1.8E-11 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS10405 bf3db9ef4870387892edaa21808e202e 317 Gene3D G3DSA:1.10.3720.10 21 304 4.1E-35 T 28-03-2018 CFK41_RS16370 fee0f99dcbff47863ed8cf9c46dd9960 463 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 240 422 1.2E-30 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CFK41_RS16370 fee0f99dcbff47863ed8cf9c46dd9960 463 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 122 134 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CFK41_RS16370 fee0f99dcbff47863ed8cf9c46dd9960 463 SUPERFAMILY SSF53067 235 427 2.53E-44 T 28-03-2018 CFK41_RS16370 fee0f99dcbff47863ed8cf9c46dd9960 463 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 231 9.5E-40 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CFK41_RS16370 fee0f99dcbff47863ed8cf9c46dd9960 463 Gene3D G3DSA:3.30.420.40 1 232 2.7E-54 T 28-03-2018 CFK41_RS16370 fee0f99dcbff47863ed8cf9c46dd9960 463 SUPERFAMILY SSF53067 4 232 7.38E-39 T 28-03-2018 CFK41_RS16370 fee0f99dcbff47863ed8cf9c46dd9960 463 TIGRFAM TIGR01312 XylB: xylulokinase 6 426 4.6E-123 T 28-03-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 CFK41_RS16370 fee0f99dcbff47863ed8cf9c46dd9960 463 Gene3D G3DSA:3.30.420.40 233 462 4.0E-47 T 28-03-2018 CFK41_RS16370 fee0f99dcbff47863ed8cf9c46dd9960 463 PIRSF PIRSF000538 2 436 2.4E-75 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CFK41_RS01510 cd1d6774443aa39ea029c95a617f11a0 886 Pfam PF01301 Glycosyl hydrolases family 35 15 252 9.2E-53 T 28-03-2018 IPR031330 Glycoside hydrolase 35, catalytic domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CFK41_RS01510 cd1d6774443aa39ea029c95a617f11a0 886 SUPERFAMILY SSF51445 13 325 1.24E-53 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS01510 cd1d6774443aa39ea029c95a617f11a0 886 Gene3D G3DSA:3.20.20.80 2 330 1.4E-38 T 28-03-2018 CFK41_RS01510 cd1d6774443aa39ea029c95a617f11a0 886 PRINTS PR00742 Glycosyl hydrolase family 35 signature 153 168 3.4E-14 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CFK41_RS01510 cd1d6774443aa39ea029c95a617f11a0 886 PRINTS PR00742 Glycosyl hydrolase family 35 signature 95 114 3.4E-14 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CFK41_RS01510 cd1d6774443aa39ea029c95a617f11a0 886 PRINTS PR00742 Glycosyl hydrolase family 35 signature 39 57 3.4E-14 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CFK41_RS01510 cd1d6774443aa39ea029c95a617f11a0 886 PRINTS PR00742 Glycosyl hydrolase family 35 signature 295 311 3.4E-14 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CFK41_RS01510 cd1d6774443aa39ea029c95a617f11a0 886 PRINTS PR00742 Glycosyl hydrolase family 35 signature 18 35 3.4E-14 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CFK41_RS01400 2686a046bf9c1df813240420168d9c14 445 Gene3D G3DSA:3.40.50.720 1 155 2.9E-29 T 28-03-2018 CFK41_RS01400 2686a046bf9c1df813240420168d9c14 445 SUPERFAMILY SSF51735 4 168 1.05E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS01400 2686a046bf9c1df813240420168d9c14 445 SUPERFAMILY SSF55347 280 330 2.35E-26 T 28-03-2018 CFK41_RS01400 2686a046bf9c1df813240420168d9c14 445 SUPERFAMILY SSF55347 142 227 2.35E-26 T 28-03-2018 CFK41_RS01400 2686a046bf9c1df813240420168d9c14 445 Gene3D G3DSA:3.30.360.10 156 443 3.7E-43 T 28-03-2018 CFK41_RS01400 2686a046bf9c1df813240420168d9c14 445 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 136 1.6E-14 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS01400 2686a046bf9c1df813240420168d9c14 445 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 149 228 1.5E-17 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CFK41_RS04465 4368cface565d4adbcc3c09aab9e58cb 339 Gene3D G3DSA:3.20.20.140 3 339 1.4E-67 T 28-03-2018 CFK41_RS04465 4368cface565d4adbcc3c09aab9e58cb 339 Pfam PF00962 Adenosine/AMP deaminase 14 331 2.7E-67 T 28-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 CFK41_RS04465 4368cface565d4adbcc3c09aab9e58cb 339 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 14 334 8.4E-85 T 28-03-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 CFK41_RS04465 4368cface565d4adbcc3c09aab9e58cb 339 ProSitePatterns PS00485 Adenosine and AMP deaminase signature. 279 285 - T 28-03-2018 IPR006650 Adenosine/AMP deaminase active site GO:0009168|GO:0019239 Reactome: R-HSA-74217 CFK41_RS04465 4368cface565d4adbcc3c09aab9e58cb 339 SUPERFAMILY SSF51556 11 328 3.24E-53 T 28-03-2018 IPR032466 Metal-dependent hydrolase CFK41_RS05430 efcb4d5d275319126a45292035042cd5 338 Pfam PF06737 Transglycosylase-like domain 49 124 1.5E-34 T 28-03-2018 IPR010618 Transglycosylase-like CFK41_RS05430 efcb4d5d275319126a45292035042cd5 338 Gene3D G3DSA:1.10.101.10 287 315 0.019 T 28-03-2018 IPR002477 Peptidoglycan binding-like CFK41_RS05430 efcb4d5d275319126a45292035042cd5 338 Gene3D G3DSA:1.10.101.10 270 286 0.094 T 28-03-2018 IPR002477 Peptidoglycan binding-like CFK41_RS05430 efcb4d5d275319126a45292035042cd5 338 SUPERFAMILY SSF53955 51 126 1.24E-30 T 28-03-2018 IPR023346 Lysozyme-like domain CFK41_RS05430 efcb4d5d275319126a45292035042cd5 338 Gene3D G3DSA:1.10.101.10 252 269 0.2 T 28-03-2018 IPR002477 Peptidoglycan binding-like CFK41_RS05430 efcb4d5d275319126a45292035042cd5 338 Gene3D G3DSA:1.10.530.10 17 129 3.2E-29 T 28-03-2018 CFK41_RS12240 2dd2f692c38d06a9f71fe441860a881c 188 PRINTS PR01576 Peptide deformylase signature 126 155 1.9E-27 T 28-03-2018 IPR023635 Peptide deformylase CFK41_RS12240 2dd2f692c38d06a9f71fe441860a881c 188 PRINTS PR01576 Peptide deformylase signature 94 105 1.9E-27 T 28-03-2018 IPR023635 Peptide deformylase CFK41_RS12240 2dd2f692c38d06a9f71fe441860a881c 188 PRINTS PR01576 Peptide deformylase signature 33 62 1.9E-27 T 28-03-2018 IPR023635 Peptide deformylase CFK41_RS12240 2dd2f692c38d06a9f71fe441860a881c 188 PRINTS PR01576 Peptide deformylase signature 106 124 1.9E-27 T 28-03-2018 IPR023635 Peptide deformylase CFK41_RS12240 2dd2f692c38d06a9f71fe441860a881c 188 Gene3D G3DSA:3.90.45.10 1 172 1.5E-48 T 28-03-2018 IPR023635 Peptide deformylase CFK41_RS12240 2dd2f692c38d06a9f71fe441860a881c 188 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 159 6.8E-32 T 28-03-2018 IPR023635 Peptide deformylase CFK41_RS12240 2dd2f692c38d06a9f71fe441860a881c 188 Pfam PF01327 Polypeptide deformylase 4 156 7.1E-35 T 28-03-2018 IPR023635 Peptide deformylase CFK41_RS12240 2dd2f692c38d06a9f71fe441860a881c 188 SUPERFAMILY SSF56420 1 163 4.71E-46 T 28-03-2018 IPR023635 Peptide deformylase CFK41_RS12240 2dd2f692c38d06a9f71fe441860a881c 188 PIRSF PIRSF004749 1 173 2.3E-37 T 28-03-2018 IPR023635 Peptide deformylase CFK41_RS12240 2dd2f692c38d06a9f71fe441860a881c 188 Hamap MF_00163 Peptide deformylase [def]. 2 168 24.826 T 28-03-2018 IPR023635 Peptide deformylase CFK41_RS10045 1eff7d658bc2f420ad6de911a24c8515 596 PIRSF PIRSF006337 2 581 1.6E-201 T 28-03-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CFK41_RS10045 1eff7d658bc2f420ad6de911a24c8515 596 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 14 538 1.1E-199 T 28-03-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CFK41_RS10045 1eff7d658bc2f420ad6de911a24c8515 596 SMART SM00642 109 512 2.0E-9 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CFK41_RS10045 1eff7d658bc2f420ad6de911a24c8515 596 Pfam PF11941 Domain of unknown function (DUF3459) 504 586 7.9E-8 T 28-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) CFK41_RS10045 1eff7d658bc2f420ad6de911a24c8515 596 Gene3D G3DSA:2.60.40.10 5 88 1.8E-17 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS10045 1eff7d658bc2f420ad6de911a24c8515 596 Gene3D G3DSA:3.20.20.80 98 520 1.8E-79 T 28-03-2018 CFK41_RS10045 1eff7d658bc2f420ad6de911a24c8515 596 SUPERFAMILY SSF51445 94 519 3.05E-105 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS10045 1eff7d658bc2f420ad6de911a24c8515 596 SUPERFAMILY SSF81296 12 88 3.6E-15 T 28-03-2018 IPR014756 Immunoglobulin E-set CFK41_RS10045 1eff7d658bc2f420ad6de911a24c8515 596 Pfam PF00128 Alpha amylase, catalytic domain 124 216 5.4E-12 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CFK41_RS08260 e7a89bd6cc9e37fd33178e8a050d86e6 154 Gene3D G3DSA:1.10.10.10 1 79 7.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS08260 e7a89bd6cc9e37fd33178e8a050d86e6 154 Pfam PF01475 Ferric uptake regulator family 3 118 1.3E-31 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CFK41_RS08260 e7a89bd6cc9e37fd33178e8a050d86e6 154 SUPERFAMILY SSF46785 3 124 1.25E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS09715 e21bf51e5490d475f250c16f8498c91e 904 Gene3D G3DSA:3.40.50.261 335 493 5.7E-25 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CFK41_RS09715 e21bf51e5490d475f250c16f8498c91e 904 SUPERFAMILY SSF52210 503 636 1.02E-5 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CFK41_RS09715 e21bf51e5490d475f250c16f8498c91e 904 Pfam PF13420 Acetyltransferase (GNAT) domain 43 180 2.3E-9 T 28-03-2018 CFK41_RS09715 e21bf51e5490d475f250c16f8498c91e 904 Gene3D G3DSA:3.40.50.261 494 711 2.9E-6 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CFK41_RS09715 e21bf51e5490d475f250c16f8498c91e 904 Gene3D G3DSA:3.30.470.20 757 888 4.1E-27 T 28-03-2018 CFK41_RS09715 e21bf51e5490d475f250c16f8498c91e 904 Gene3D G3DSA:3.40.630.30 31 214 1.8E-24 T 28-03-2018 CFK41_RS09715 e21bf51e5490d475f250c16f8498c91e 904 Gene3D G3DSA:3.40.50.720 215 334 6.9E-31 T 28-03-2018 CFK41_RS09715 e21bf51e5490d475f250c16f8498c91e 904 Gene3D G3DSA:3.30.1490.20 712 756 3.9E-13 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CFK41_RS09715 e21bf51e5490d475f250c16f8498c91e 904 SUPERFAMILY SSF52210 341 499 4.32E-22 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CFK41_RS09715 e21bf51e5490d475f250c16f8498c91e 904 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 361 497 8.4E-31 T 28-03-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain CFK41_RS09715 e21bf51e5490d475f250c16f8498c91e 904 Pfam PF13549 ATP-grasp domain 674 883 1.1E-46 T 28-03-2018 CFK41_RS09715 e21bf51e5490d475f250c16f8498c91e 904 SUPERFAMILY SSF55729 41 181 1.77E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS09715 e21bf51e5490d475f250c16f8498c91e 904 SUPERFAMILY SSF51735 208 345 2.79E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS09715 e21bf51e5490d475f250c16f8498c91e 904 Pfam PF13380 CoA binding domain 219 342 6.9E-15 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CFK41_RS09715 e21bf51e5490d475f250c16f8498c91e 904 SMART SM00881 215 310 2.6E-24 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CFK41_RS09715 e21bf51e5490d475f250c16f8498c91e 904 SUPERFAMILY SSF56059 682 878 4.01E-22 T 28-03-2018 CFK41_RS01805 04920b182e16fd587348ff5d0b49f34e 181 Gene3D G3DSA:3.40.50.300 3 175 4.3E-17 T 28-03-2018 CFK41_RS01805 04920b182e16fd587348ff5d0b49f34e 181 Pfam PF13238 AAA domain 8 114 5.1E-8 T 28-03-2018 CFK41_RS01805 04920b182e16fd587348ff5d0b49f34e 181 SUPERFAMILY SSF52540 7 174 8.0E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS08685 450beca8736f580dc3d6413149036a2f 321 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 299 2.0E-67 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CFK41_RS08685 450beca8736f580dc3d6413149036a2f 321 SUPERFAMILY SSF53328 1 203 1.44E-54 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CFK41_RS08685 450beca8736f580dc3d6413149036a2f 321 Gene3D G3DSA:3.40.50.170 1 205 1.7E-58 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CFK41_RS08685 450beca8736f580dc3d6413149036a2f 321 SUPERFAMILY SSF50486 205 303 6.12E-25 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CFK41_RS08685 450beca8736f580dc3d6413149036a2f 321 Pfam PF02911 Formyl transferase, C-terminal domain 203 299 8.2E-23 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CFK41_RS08685 450beca8736f580dc3d6413149036a2f 321 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 302 32.627 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CFK41_RS08685 450beca8736f580dc3d6413149036a2f 321 Gene3D G3DSA:3.10.25.10 206 305 4.3E-26 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CFK41_RS08685 450beca8736f580dc3d6413149036a2f 321 Pfam PF00551 Formyl transferase 7 180 5.5E-35 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CFK41_RS12025 69afeecf2ccbd3f9cae0ce52782ef52f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 1.7E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS12025 69afeecf2ccbd3f9cae0ce52782ef52f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.7E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS12025 69afeecf2ccbd3f9cae0ce52782ef52f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.7E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS12025 69afeecf2ccbd3f9cae0ce52782ef52f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.7E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS12025 69afeecf2ccbd3f9cae0ce52782ef52f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.7E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS12025 69afeecf2ccbd3f9cae0ce52782ef52f 261 Pfam PF00106 short chain dehydrogenase 14 194 1.8E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS12025 69afeecf2ccbd3f9cae0ce52782ef52f 261 SUPERFAMILY SSF51735 14 243 1.33E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS12025 69afeecf2ccbd3f9cae0ce52782ef52f 261 Gene3D G3DSA:3.40.50.720 11 258 8.1E-52 T 28-03-2018 CFK41_RS03400 ca324c73cef9ec4ae94c69d8eaa1543b 309 Pfam PF00753 Metallo-beta-lactamase superfamily 66 224 1.2E-14 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS03400 ca324c73cef9ec4ae94c69d8eaa1543b 309 Gene3D G3DSA:3.60.15.10 45 281 2.5E-28 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS03400 ca324c73cef9ec4ae94c69d8eaa1543b 309 SMART SM00849 68 235 8.0E-19 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS03400 ca324c73cef9ec4ae94c69d8eaa1543b 309 SUPERFAMILY SSF56281 62 306 1.54E-36 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS09560 69dfd116775938d12388f9708d765c41 206 SUPERFAMILY SSF46785 142 179 1.09E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS09560 69dfd116775938d12388f9708d765c41 206 Gene3D G3DSA:1.10.10.10 112 167 8.5E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS09560 69dfd116775938d12388f9708d765c41 206 Gene3D G3DSA:1.10.10.10 168 196 0.0016 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS09560 69dfd116775938d12388f9708d765c41 206 Pfam PF13412 Winged helix-turn-helix DNA-binding 150 179 8.7E-9 T 28-03-2018 CFK41_RS05395 8bb6387f06270d7fae2461a1b5daf4cf 362 SUPERFAMILY SSF53850 108 325 4.53E-9 T 28-03-2018 CFK41_RS05395 8bb6387f06270d7fae2461a1b5daf4cf 362 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 94 360 2.8E-27 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CFK41_RS05395 8bb6387f06270d7fae2461a1b5daf4cf 362 Gene3D G3DSA:3.40.190.10 173 335 5.9E-14 T 28-03-2018 CFK41_RS05395 8bb6387f06270d7fae2461a1b5daf4cf 362 PIRSF PIRSF017082 37 361 3.5E-75 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CFK41_RS15475 ad7e925b772b8ac320533594023e6368 452 SUPERFAMILY SSF53649 20 428 3.34E-52 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CFK41_RS15475 ad7e925b772b8ac320533594023e6368 452 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 23 285 4.8E-40 T 28-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 CFK41_RS15475 ad7e925b772b8ac320533594023e6368 452 Gene3D G3DSA:3.40.720.10 20 452 9.1E-41 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CFK41_RS10655 a2f36084399a1a523b77a161bbe42536 467 Gene3D G3DSA:3.40.190.10 31 198 4.1E-25 T 28-03-2018 CFK41_RS10655 a2f36084399a1a523b77a161bbe42536 467 Pfam PF13416 Bacterial extracellular solute-binding protein 57 381 1.1E-22 T 28-03-2018 CFK41_RS10655 a2f36084399a1a523b77a161bbe42536 467 Gene3D G3DSA:3.40.190.10 199 402 3.4E-5 T 28-03-2018 CFK41_RS10655 a2f36084399a1a523b77a161bbe42536 467 SUPERFAMILY SSF53850 41 439 4.35E-51 T 28-03-2018 CFK41_RS11805 99f641f83e4ae7aeabc2c2c275e6b24c 401 Gene3D G3DSA:3.40.50.720 6 160 3.5E-37 T 28-03-2018 CFK41_RS11805 99f641f83e4ae7aeabc2c2c275e6b24c 401 SUPERFAMILY SSF51735 7 160 1.31E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS11805 99f641f83e4ae7aeabc2c2c275e6b24c 401 Gene3D G3DSA:1.10.1740.10 313 397 6.6E-20 T 28-03-2018 CFK41_RS11805 99f641f83e4ae7aeabc2c2c275e6b24c 401 SUPERFAMILY SSF55347 138 274 4.58E-51 T 28-03-2018 CFK41_RS11805 99f641f83e4ae7aeabc2c2c275e6b24c 401 SUPERFAMILY SSF69055 303 397 2.75E-21 T 28-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CFK41_RS11805 99f641f83e4ae7aeabc2c2c275e6b24c 401 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 7 393 2.4E-105 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CFK41_RS11805 99f641f83e4ae7aeabc2c2c275e6b24c 401 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 9 144 5.3E-31 T 28-03-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CFK41_RS11805 99f641f83e4ae7aeabc2c2c275e6b24c 401 Pfam PF13288 DXP reductoisomerase C-terminal domain 272 390 7.2E-28 T 28-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CFK41_RS11805 99f641f83e4ae7aeabc2c2c275e6b24c 401 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 9 395 40.041 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CFK41_RS11805 99f641f83e4ae7aeabc2c2c275e6b24c 401 PIRSF PIRSF006205 6 401 4.5E-123 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CFK41_RS11805 99f641f83e4ae7aeabc2c2c275e6b24c 401 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 156 239 1.1E-33 T 28-03-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CFK41_RS00610 9edcda809ece61ddc840c58403b17115 447 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 193 215 2.5E-31 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CFK41_RS00610 9edcda809ece61ddc840c58403b17115 447 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 113 127 2.5E-31 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CFK41_RS00610 9edcda809ece61ddc840c58403b17115 447 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 371 382 2.5E-31 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CFK41_RS00610 9edcda809ece61ddc840c58403b17115 447 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 235 255 2.5E-31 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CFK41_RS00610 9edcda809ece61ddc840c58403b17115 447 SMART SM00839 204 445 8.3E-85 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CFK41_RS00610 9edcda809ece61ddc840c58403b17115 447 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 202 445 1.9E-84 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CFK41_RS00610 9edcda809ece61ddc840c58403b17115 447 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 56 184 1.7E-48 T 28-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CFK41_RS00610 9edcda809ece61ddc840c58403b17115 447 Gene3D G3DSA:1.10.285.10 373 447 2.4E-23 T 28-03-2018 CFK41_RS00610 9edcda809ece61ddc840c58403b17115 447 Gene3D G3DSA:1.10.285.10 5 59 1.1E-6 T 28-03-2018 CFK41_RS00610 9edcda809ece61ddc840c58403b17115 447 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 121 134 - T 28-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CFK41_RS00610 9edcda809ece61ddc840c58403b17115 447 Gene3D G3DSA:3.40.50.720 209 372 7.9E-43 T 28-03-2018 CFK41_RS00610 9edcda809ece61ddc840c58403b17115 447 SUPERFAMILY SSF51735 202 446 1.25E-70 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS00610 9edcda809ece61ddc840c58403b17115 447 SUPERFAMILY SSF53223 6 196 2.14E-73 T 28-03-2018 CFK41_RS00610 9edcda809ece61ddc840c58403b17115 447 Gene3D G3DSA:3.40.50.10860 60 189 2.8E-53 T 28-03-2018 CFK41_RS00610 9edcda809ece61ddc840c58403b17115 447 PIRSF PIRSF000185 21 447 1.8E-115 T 28-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 CFK41_RS04285 71f2fcc1fbd5197232797ac0b87d1925 221 Gene3D G3DSA:3.40.50.720 9 139 1.9E-18 T 28-03-2018 CFK41_RS04285 71f2fcc1fbd5197232797ac0b87d1925 221 SUPERFAMILY SSF116726 135 218 8.76E-15 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CFK41_RS04285 71f2fcc1fbd5197232797ac0b87d1925 221 SUPERFAMILY SSF51735 10 138 1.81E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS04285 71f2fcc1fbd5197232797ac0b87d1925 221 Pfam PF02080 TrkA-C domain 157 218 2.3E-7 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CFK41_RS04285 71f2fcc1fbd5197232797ac0b87d1925 221 Gene3D G3DSA:3.30.70.1450 140 220 2.7E-13 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CFK41_RS04285 71f2fcc1fbd5197232797ac0b87d1925 221 Pfam PF02254 TrkA-N domain 10 125 4.4E-23 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CFK41_RS06430 67c7460b67a97a23fd157b292e01c5ea 245 Gene3D G3DSA:3.40.50.300 16 243 1.4E-60 T 28-03-2018 CFK41_RS06430 67c7460b67a97a23fd157b292e01c5ea 245 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS06430 67c7460b67a97a23fd157b292e01c5ea 245 SMART SM00382 48 234 1.7E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS06430 67c7460b67a97a23fd157b292e01c5ea 245 Pfam PF00005 ABC transporter 39 185 3.2E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS06430 67c7460b67a97a23fd157b292e01c5ea 245 SUPERFAMILY SSF52540 21 240 1.86E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS17265 53cdc6c89563839b3fcc13a88a624311 478 Pfam PF07690 Major Facilitator Superfamily 37 415 3.3E-28 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS17265 53cdc6c89563839b3fcc13a88a624311 478 SUPERFAMILY SSF103473 255 457 2.49E-40 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS17265 53cdc6c89563839b3fcc13a88a624311 478 SUPERFAMILY SSF103473 1 211 2.49E-40 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS17265 53cdc6c89563839b3fcc13a88a624311 478 Gene3D G3DSA:1.20.1250.20 18 204 3.9E-23 T 28-03-2018 CFK41_RS17265 53cdc6c89563839b3fcc13a88a624311 478 Gene3D G3DSA:1.20.1250.20 274 462 6.4E-12 T 28-03-2018 CFK41_RS17265 53cdc6c89563839b3fcc13a88a624311 478 PRINTS PR01036 Tetracycline resistance protein TetB signature 120 140 6.8E-7 T 28-03-2018 CFK41_RS17265 53cdc6c89563839b3fcc13a88a624311 478 PRINTS PR01036 Tetracycline resistance protein TetB signature 403 422 6.8E-7 T 28-03-2018 CFK41_RS17265 53cdc6c89563839b3fcc13a88a624311 478 PRINTS PR01036 Tetracycline resistance protein TetB signature 150 174 6.8E-7 T 28-03-2018 CFK41_RS08890 8ee3300e67bba67c89a3c19232ed399b 1141 Gene3D G3DSA:3.20.20.140 50 331 9.7E-29 T 28-03-2018 CFK41_RS08890 8ee3300e67bba67c89a3c19232ed399b 1141 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 374 791 9.3E-138 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CFK41_RS08890 8ee3300e67bba67c89a3c19232ed399b 1141 SMART SM00481 52 119 2.7E-18 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CFK41_RS08890 8ee3300e67bba67c89a3c19232ed399b 1141 SUPERFAMILY SSF89550 51 153 2.94E-15 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CFK41_RS08890 8ee3300e67bba67c89a3c19232ed399b 1141 SUPERFAMILY SSF89550 213 293 2.94E-15 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CFK41_RS08890 8ee3300e67bba67c89a3c19232ed399b 1141 Gene3D G3DSA:2.40.50.140 1038 1134 6.3E-7 T 28-03-2018 CFK41_RS08890 8ee3300e67bba67c89a3c19232ed399b 1141 Pfam PF14579 Helix-hairpin-helix motif 865 975 4.8E-25 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CFK41_RS08890 8ee3300e67bba67c89a3c19232ed399b 1141 Pfam PF02811 PHP domain 53 229 2.5E-23 T 28-03-2018 IPR004013 PHP domain GO:0003824 CFK41_RS08890 8ee3300e67bba67c89a3c19232ed399b 1141 Gene3D G3DSA:1.10.150.280 905 971 1.9E-8 T 28-03-2018 CFK41_RS08890 8ee3300e67bba67c89a3c19232ed399b 1141 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 52 1086 3.7E-176 T 28-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CFK41_RS08890 8ee3300e67bba67c89a3c19232ed399b 1141 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 51 1141 12.127 T 28-03-2018 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CFK41_RS08225 ddff6bf42234ceb61220e281199b7d7b 238 Pfam PF12787 EcsC protein family 79 234 1.9E-9 T 28-03-2018 IPR024787 EcsC protein CFK41_RS05345 c06f78ed15576119e7def6cdfa3ced0a 164 Gene3D G3DSA:2.30.110.10 1 163 2.4E-34 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CFK41_RS05345 c06f78ed15576119e7def6cdfa3ced0a 164 SUPERFAMILY SSF50475 5 157 2.4E-36 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CFK41_RS05345 c06f78ed15576119e7def6cdfa3ced0a 164 SMART SM00903 11 156 4.8E-35 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CFK41_RS05345 c06f78ed15576119e7def6cdfa3ced0a 164 Pfam PF01613 Flavin reductase like domain 12 157 6.1E-25 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CFK41_RS01205 353f2f82e00a6490e8ad6c2aab428ee8 456 Gene3D G3DSA:1.20.1250.20 249 456 1.3E-30 T 28-03-2018 CFK41_RS01205 353f2f82e00a6490e8ad6c2aab428ee8 456 ProSitePatterns PS00217 Sugar transport proteins signature 2. 132 157 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CFK41_RS01205 353f2f82e00a6490e8ad6c2aab428ee8 456 ProSitePatterns PS00216 Sugar transport proteins signature 1. 90 106 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CFK41_RS01205 353f2f82e00a6490e8ad6c2aab428ee8 456 SUPERFAMILY SSF103473 1 454 1.44E-83 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS01205 353f2f82e00a6490e8ad6c2aab428ee8 456 Pfam PF00083 Sugar (and other) transporter 72 456 7.9E-53 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CFK41_RS01205 353f2f82e00a6490e8ad6c2aab428ee8 456 Gene3D G3DSA:1.20.1250.20 32 228 6.4E-33 T 28-03-2018 CFK41_RS01405 737397e4c7612bc9ea6bc8079c296dfb 702 Gene3D G3DSA:1.50.10.10 262 672 3.9E-54 T 28-03-2018 CFK41_RS01405 737397e4c7612bc9ea6bc8079c296dfb 702 SUPERFAMILY SSF48208 294 692 1.93E-42 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CFK41_RS01405 737397e4c7612bc9ea6bc8079c296dfb 702 Gene3D G3DSA:2.70.98.50 120 261 2.2E-4 T 28-03-2018 CFK41_RS10730 ca4e08dbb78d708debce11d749347042 381 Pfam PF13439 Glycosyltransferase Family 4 15 185 5.8E-24 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CFK41_RS10730 ca4e08dbb78d708debce11d749347042 381 Gene3D G3DSA:3.40.50.2000 204 356 2.7E-35 T 28-03-2018 CFK41_RS10730 ca4e08dbb78d708debce11d749347042 381 Gene3D G3DSA:3.40.50.2000 1 203 8.0E-19 T 28-03-2018 CFK41_RS10730 ca4e08dbb78d708debce11d749347042 381 SUPERFAMILY SSF53756 2 367 5.76E-69 T 28-03-2018 CFK41_RS10730 ca4e08dbb78d708debce11d749347042 381 Pfam PF00534 Glycosyl transferases group 1 203 349 7.6E-24 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CFK41_RS07575 e8ab73d7b3b3efc6f2329c0b0bd282b7 304 Pfam PF00248 Aldo/keto reductase family 3 281 6.0E-63 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS07575 e8ab73d7b3b3efc6f2329c0b0bd282b7 304 Gene3D G3DSA:3.20.20.100 1 303 1.1E-80 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS07575 e8ab73d7b3b3efc6f2329c0b0bd282b7 304 SUPERFAMILY SSF51430 4 282 6.42E-76 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS04330 f961b888998e7774d5fe9dd3724a38eb 185 Gene3D G3DSA:1.10.10.10 40 169 1.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS04330 f961b888998e7774d5fe9dd3724a38eb 185 Pfam PF12802 MarR family 56 116 2.1E-11 T 28-03-2018 CFK41_RS04330 f961b888998e7774d5fe9dd3724a38eb 185 SUPERFAMILY SSF46785 18 165 5.65E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS04330 f961b888998e7774d5fe9dd3724a38eb 185 SMART SM00347 50 153 1.8E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS04330 f961b888998e7774d5fe9dd3724a38eb 185 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 108 5.4E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS04330 f961b888998e7774d5fe9dd3724a38eb 185 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 92 5.4E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS04330 f961b888998e7774d5fe9dd3724a38eb 185 PRINTS PR00598 Bacterial regulatory protein MarR family signature 112 128 5.4E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS06490 b556d6cce2e610a7441c43304ed5152d 371 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 5 363 4.3E-147 T 28-03-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 CFK41_RS06490 b556d6cce2e610a7441c43304ed5152d 371 Pfam PF00472 RF-1 domain 229 336 7.2E-35 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CFK41_RS06490 b556d6cce2e610a7441c43304ed5152d 371 Gene3D G3DSA:1.20.58.410 3 115 8.6E-26 T 28-03-2018 CFK41_RS06490 b556d6cce2e610a7441c43304ed5152d 371 Gene3D G3DSA:3.30.160.20 224 319 4.8E-30 T 28-03-2018 CFK41_RS06490 b556d6cce2e610a7441c43304ed5152d 371 SMART SM00937 84 194 1.9E-50 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CFK41_RS06490 b556d6cce2e610a7441c43304ed5152d 371 SUPERFAMILY SSF75620 29 365 7.98E-119 T 28-03-2018 CFK41_RS06490 b556d6cce2e610a7441c43304ed5152d 371 Pfam PF03462 PCRF domain 30 219 8.2E-59 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CFK41_RS06490 b556d6cce2e610a7441c43304ed5152d 371 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 244 260 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CFK41_RS08080 6d91be32d9285218b1f4b0722b6fdf8c 211 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 89 206 9.1E-9 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CFK41_RS08080 6d91be32d9285218b1f4b0722b6fdf8c 211 SUPERFAMILY SSF50118 87 205 4.14E-8 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CFK41_RS08080 6d91be32d9285218b1f4b0722b6fdf8c 211 Gene3D G3DSA:2.30.30.110 82 210 5.7E-16 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CFK41_RS09835 3c8046f8e9c17602e331dd85bf6d9297 93 SUPERFAMILY SSF54909 2 78 1.27E-17 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CFK41_RS09835 3c8046f8e9c17602e331dd85bf6d9297 93 Gene3D G3DSA:3.30.70.920 1 83 3.1E-18 T 28-03-2018 CFK41_RS09835 3c8046f8e9c17602e331dd85bf6d9297 93 Pfam PF01037 Lrp/AsnC ligand binding domain 6 77 9.4E-15 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CFK41_RS15140 68dec7e2b1117e1e615abfc99a4f324e 294 Gene3D G3DSA:1.10.3720.10 61 294 9.7E-33 T 28-03-2018 CFK41_RS15140 68dec7e2b1117e1e615abfc99a4f324e 294 Gene3D G3DSA:1.20.58.370 1 36 1.3E-4 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CFK41_RS15140 68dec7e2b1117e1e615abfc99a4f324e 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 286 4.6E-10 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS15140 68dec7e2b1117e1e615abfc99a4f324e 294 SUPERFAMILY SSF161098 55 281 2.09E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS15085 fcaadbf24526a910503cf623aa6cda77 511 SUPERFAMILY SSF51905 11 187 5.78E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS15085 fcaadbf24526a910503cf623aa6cda77 511 SUPERFAMILY SSF51905 270 376 5.78E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS15085 fcaadbf24526a910503cf623aa6cda77 511 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 166 181 3.3E-35 T 28-03-2018 CFK41_RS15085 fcaadbf24526a910503cf623aa6cda77 511 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 314 3.3E-35 T 28-03-2018 CFK41_RS15085 fcaadbf24526a910503cf623aa6cda77 511 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 334 350 3.3E-35 T 28-03-2018 CFK41_RS15085 fcaadbf24526a910503cf623aa6cda77 511 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 13 35 3.3E-35 T 28-03-2018 CFK41_RS15085 fcaadbf24526a910503cf623aa6cda77 511 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 298 3.3E-35 T 28-03-2018 CFK41_RS15085 fcaadbf24526a910503cf623aa6cda77 511 Gene3D G3DSA:3.50.50.60 10 354 2.4E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS15085 fcaadbf24526a910503cf623aa6cda77 511 Pfam PF01494 FAD binding domain 11 345 2.1E-65 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CFK41_RS00845 7fc7b1b247f3e994defe8189bbc2278d 225 Gene3D G3DSA:1.20.1250.20 70 219 9.4E-5 T 28-03-2018 CFK41_RS00845 7fc7b1b247f3e994defe8189bbc2278d 225 SUPERFAMILY SSF103473 63 221 3.66E-5 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS00845 7fc7b1b247f3e994defe8189bbc2278d 225 Pfam PF06197 Protein of unknown function (DUF998) 26 202 3.2E-15 T 28-03-2018 IPR009339 Protein of unknown function DUF998 CFK41_RS03845 29ddf9d6b41fd84b846fab1d8fcc4f10 380 Pfam PF08281 Sigma-70, region 4 100 149 4.2E-8 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS03845 29ddf9d6b41fd84b846fab1d8fcc4f10 380 Gene3D G3DSA:1.10.10.10 69 156 2.8E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS03845 29ddf9d6b41fd84b846fab1d8fcc4f10 380 Gene3D G3DSA:1.10.1740.10 3 68 4.5E-15 T 28-03-2018 CFK41_RS03845 29ddf9d6b41fd84b846fab1d8fcc4f10 380 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 149 7.2E-13 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS03845 29ddf9d6b41fd84b846fab1d8fcc4f10 380 SUPERFAMILY SSF88946 3 82 2.2E-12 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS03845 29ddf9d6b41fd84b846fab1d8fcc4f10 380 SUPERFAMILY SSF88659 94 150 5.23E-9 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS03845 29ddf9d6b41fd84b846fab1d8fcc4f10 380 Pfam PF04542 Sigma-70 region 2 5 70 5.3E-10 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS07980 3aeb4f8229f73c015a687d1317f6811f 254 Pfam PF02585 GlcNAc-PI de-N-acetylase 31 157 1.8E-24 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CFK41_RS07980 3aeb4f8229f73c015a687d1317f6811f 254 SUPERFAMILY SSF102588 28 218 7.98E-37 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CFK41_RS07980 3aeb4f8229f73c015a687d1317f6811f 254 Gene3D G3DSA:3.40.50.10320 5 254 4.1E-42 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CFK41_RS15930 4ace528dc7b916e8fdc168ed8bae8da8 442 Gene3D G3DSA:3.10.580.10 195 345 9.7E-31 T 28-03-2018 CFK41_RS15930 4ace528dc7b916e8fdc168ed8bae8da8 442 SUPERFAMILY SSF56176 360 435 7.91E-18 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CFK41_RS15930 4ace528dc7b916e8fdc168ed8bae8da8 442 Gene3D G3DSA:3.30.465.10 358 429 1.1E-21 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CFK41_RS15930 4ace528dc7b916e8fdc168ed8bae8da8 442 SMART SM00116 223 272 1.5 T 28-03-2018 IPR000644 CBS domain CFK41_RS15930 4ace528dc7b916e8fdc168ed8bae8da8 442 SMART SM00116 284 332 9.9 T 28-03-2018 IPR000644 CBS domain CFK41_RS15930 4ace528dc7b916e8fdc168ed8bae8da8 442 Pfam PF00571 CBS domain 220 269 3.0E-5 T 28-03-2018 IPR000644 CBS domain CFK41_RS15930 4ace528dc7b916e8fdc168ed8bae8da8 442 Pfam PF00571 CBS domain 287 332 1.7E-5 T 28-03-2018 IPR000644 CBS domain CFK41_RS15930 4ace528dc7b916e8fdc168ed8bae8da8 442 Pfam PF01595 Domain of unknown function DUF21 11 194 4.1E-39 T 28-03-2018 IPR002550 Domain of unknown function DUF21 CFK41_RS15930 4ace528dc7b916e8fdc168ed8bae8da8 442 SMART SM01091 351 430 7.1E-20 T 28-03-2018 IPR005170 Transporter-associated domain CFK41_RS15930 4ace528dc7b916e8fdc168ed8bae8da8 442 SUPERFAMILY SSF54631 211 342 2.27E-26 T 28-03-2018 CFK41_RS15930 4ace528dc7b916e8fdc168ed8bae8da8 442 Pfam PF03471 Transporter associated domain 360 427 3.0E-19 T 28-03-2018 IPR005170 Transporter-associated domain CFK41_RS09975 903a8eaba2617aeb08f080f5699372a1 252 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 238 5.8E-95 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS09975 903a8eaba2617aeb08f080f5699372a1 252 Pfam PF01709 Transcriptional regulator 5 238 4.0E-89 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS09975 903a8eaba2617aeb08f080f5699372a1 252 Gene3D G3DSA:3.30.70.980 179 249 7.7E-13 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS09975 903a8eaba2617aeb08f080f5699372a1 252 Gene3D G3DSA:3.30.70.980 84 178 4.7E-29 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS09975 903a8eaba2617aeb08f080f5699372a1 252 Gene3D G3DSA:1.10.10.200 1 77 2.5E-30 T 28-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like CFK41_RS09975 903a8eaba2617aeb08f080f5699372a1 252 SUPERFAMILY SSF75625 3 247 1.07E-89 T 28-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS09975 903a8eaba2617aeb08f080f5699372a1 252 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 240 34.702 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS07825 d5587c56d748d3a1ea3df94f84ceeb9a 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 304 2.4E-10 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS07825 d5587c56d748d3a1ea3df94f84ceeb9a 311 Gene3D G3DSA:1.10.3720.10 78 305 2.6E-35 T 28-03-2018 CFK41_RS07825 d5587c56d748d3a1ea3df94f84ceeb9a 311 SUPERFAMILY SSF161098 23 311 5.15E-53 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS04200 b1529ec15d683210afb8bf605eb5249e 305 Gene3D G3DSA:3.40.190.10 31 134 4.7E-16 T 28-03-2018 CFK41_RS04200 b1529ec15d683210afb8bf605eb5249e 305 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 45 294 9.3E-54 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CFK41_RS04200 b1529ec15d683210afb8bf605eb5249e 305 SUPERFAMILY SSF53850 42 299 9.72E-65 T 28-03-2018 CFK41_RS04200 b1529ec15d683210afb8bf605eb5249e 305 Gene3D G3DSA:3.40.190.100 135 252 1.9E-32 T 28-03-2018 CFK41_RS14905 94c61150f3a2d3e14c375a01078bb795 520 Gene3D G3DSA:3.30.530.20 342 520 5.3E-11 T 28-03-2018 IPR023393 START-like domain CFK41_RS14905 94c61150f3a2d3e14c375a01078bb795 520 Pfam PF11066 Protein of unknown function (DUF2867) 338 483 1.4E-34 T 28-03-2018 IPR021295 Protein of unknown function DUF2867 CFK41_RS14905 94c61150f3a2d3e14c375a01078bb795 520 SUPERFAMILY SSF51735 10 287 4.62E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS14905 94c61150f3a2d3e14c375a01078bb795 520 SUPERFAMILY SSF55961 345 493 8.93E-7 T 28-03-2018 CFK41_RS14905 94c61150f3a2d3e14c375a01078bb795 520 Gene3D G3DSA:3.40.50.720 1 310 1.8E-30 T 28-03-2018 CFK41_RS14905 94c61150f3a2d3e14c375a01078bb795 520 Pfam PF13460 NAD(P)H-binding 14 123 1.7E-19 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS04495 1f79695122c357d4c872574035a50950 239 PIRSF PIRSF002155 1 227 3.1E-72 T 28-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04495 1f79695122c357d4c872574035a50950 239 Gene3D G3DSA:3.30.190.20 150 228 4.3E-17 T 28-03-2018 CFK41_RS04495 1f79695122c357d4c872574035a50950 239 Gene3D G3DSA:3.40.50.790 68 149 2.4E-34 T 28-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich CFK41_RS04495 1f79695122c357d4c872574035a50950 239 Pfam PF00687 Ribosomal protein L1p/L10e family 32 220 2.4E-51 T 28-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein CFK41_RS04495 1f79695122c357d4c872574035a50950 239 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 1 229 41.358 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CFK41_RS04495 1f79695122c357d4c872574035a50950 239 SUPERFAMILY SSF56808 7 227 3.66E-79 T 28-03-2018 IPR023674 Ribosomal protein L1-like CFK41_RS04495 1f79695122c357d4c872574035a50950 239 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 28-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04495 1f79695122c357d4c872574035a50950 239 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 5 228 1.4E-96 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CFK41_RS03140 6f4aa4f9c7230f73e72cd9fe07d313fb 345 Pfam PF00490 Delta-aminolevulinic acid dehydratase 16 332 2.1E-135 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CFK41_RS03140 6f4aa4f9c7230f73e72cd9fe07d313fb 345 SUPERFAMILY SSF51569 13 334 7.91E-130 T 28-03-2018 CFK41_RS03140 6f4aa4f9c7230f73e72cd9fe07d313fb 345 PIRSF PIRSF001415 9 336 4.8E-140 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CFK41_RS03140 6f4aa4f9c7230f73e72cd9fe07d313fb 345 Gene3D G3DSA:3.20.20.70 6 337 2.7E-144 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS03140 6f4aa4f9c7230f73e72cd9fe07d313fb 345 SMART SM01004 13 333 5.3E-208 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CFK41_RS03140 6f4aa4f9c7230f73e72cd9fe07d313fb 345 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 252 268 4.3E-56 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CFK41_RS03140 6f4aa4f9c7230f73e72cd9fe07d313fb 345 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 201 220 4.3E-56 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CFK41_RS03140 6f4aa4f9c7230f73e72cd9fe07d313fb 345 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 163 182 4.3E-56 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CFK41_RS03140 6f4aa4f9c7230f73e72cd9fe07d313fb 345 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 277 292 4.3E-56 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CFK41_RS03140 6f4aa4f9c7230f73e72cd9fe07d313fb 345 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 307 326 4.3E-56 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CFK41_RS03140 6f4aa4f9c7230f73e72cd9fe07d313fb 345 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 132 146 4.3E-56 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CFK41_RS03140 6f4aa4f9c7230f73e72cd9fe07d313fb 345 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 252 264 - T 28-03-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CFK41_RS12995 5c5e8572ce7e6f73bd19575603258451 528 SMART SM00490 259 340 4.4E-22 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS12995 5c5e8572ce7e6f73bd19575603258451 528 Gene3D G3DSA:3.40.50.300 2 228 2.0E-49 T 28-03-2018 CFK41_RS12995 5c5e8572ce7e6f73bd19575603258451 528 SUPERFAMILY SSF52540 77 358 3.65E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS12995 5c5e8572ce7e6f73bd19575603258451 528 Pfam PF00271 Helicase conserved C-terminal domain 241 340 5.0E-20 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS12995 5c5e8572ce7e6f73bd19575603258451 528 Pfam PF00270 DEAD/DEAH box helicase 28 199 2.0E-41 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CFK41_RS12995 5c5e8572ce7e6f73bd19575603258451 528 SMART SM00487 23 225 2.8E-47 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CFK41_RS12995 5c5e8572ce7e6f73bd19575603258451 528 Gene3D G3DSA:3.40.50.300 229 507 2.7E-34 T 28-03-2018 CFK41_RS10945 8276bc2ec9f9ebf1df6f92b7b5bfd283 421 Gene3D G3DSA:3.20.20.70 32 404 4.5E-99 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS10945 8276bc2ec9f9ebf1df6f92b7b5bfd283 421 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 298 304 - T 28-03-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 CFK41_RS10945 8276bc2ec9f9ebf1df6f92b7b5bfd283 421 SUPERFAMILY SSF51395 34 400 4.87E-93 T 28-03-2018 CFK41_RS10945 8276bc2ec9f9ebf1df6f92b7b5bfd283 421 PIRSF PIRSF000138 16 405 1.8E-128 T 28-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CFK41_RS10945 8276bc2ec9f9ebf1df6f92b7b5bfd283 421 Pfam PF01070 FMN-dependent dehydrogenase 43 401 4.3E-124 T 28-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 CFK41_RS04080 4e20507428786d12de3d9d8070ad0eba 145 SUPERFAMILY SSF46785 5 139 7.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS04080 4e20507428786d12de3d9d8070ad0eba 145 ProSitePatterns PS01117 MarR-type HTH domain signature. 66 100 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CFK41_RS04080 4e20507428786d12de3d9d8070ad0eba 145 Pfam PF13463 Winged helix DNA-binding domain 41 100 3.6E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS04080 4e20507428786d12de3d9d8070ad0eba 145 Gene3D G3DSA:1.10.10.10 3 145 4.7E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS04080 4e20507428786d12de3d9d8070ad0eba 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 1.9E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS04080 4e20507428786d12de3d9d8070ad0eba 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 1.9E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS04080 4e20507428786d12de3d9d8070ad0eba 145 SMART SM00347 28 123 7.7E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS04595 25b390a04dff716b3a8290c8a1d1dff1 93 SUPERFAMILY SSF54570 3 85 7.98E-33 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04595 25b390a04dff716b3a8290c8a1d1dff1 93 PIRSF PIRSF002144 1 93 7.4E-30 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04595 25b390a04dff716b3a8290c8a1d1dff1 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 2.3E-44 T 28-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 CFK41_RS04595 25b390a04dff716b3a8290c8a1d1dff1 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 28-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04595 25b390a04dff716b3a8290c8a1d1dff1 93 Pfam PF00203 Ribosomal protein S19 3 83 2.8E-33 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04595 25b390a04dff716b3a8290c8a1d1dff1 93 Gene3D G3DSA:3.30.860.10 1 92 1.5E-36 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04595 25b390a04dff716b3a8290c8a1d1dff1 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 6.5E-22 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04595 25b390a04dff716b3a8290c8a1d1dff1 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 6.5E-22 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04595 25b390a04dff716b3a8290c8a1d1dff1 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 6.5E-22 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04595 25b390a04dff716b3a8290c8a1d1dff1 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 23.766 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS15120 63c12bb7622dc85e0822b85a02d6c519 626 PIRSF PIRSF006336 2 622 3.8E-178 T 28-03-2018 IPR026283 Beta-galactosidase 1-like GO:0004565 CFK41_RS15120 63c12bb7622dc85e0822b85a02d6c519 626 Pfam PF01301 Glycosyl hydrolases family 35 12 324 3.0E-108 T 28-03-2018 IPR031330 Glycoside hydrolase 35, catalytic domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CFK41_RS15120 63c12bb7622dc85e0822b85a02d6c519 626 SUPERFAMILY SSF51445 11 326 7.76E-92 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS15120 63c12bb7622dc85e0822b85a02d6c519 626 PRINTS PR00742 Glycosyl hydrolase family 35 signature 15 32 3.9E-49 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CFK41_RS15120 63c12bb7622dc85e0822b85a02d6c519 626 PRINTS PR00742 Glycosyl hydrolase family 35 signature 146 161 3.9E-49 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CFK41_RS15120 63c12bb7622dc85e0822b85a02d6c519 626 PRINTS PR00742 Glycosyl hydrolase family 35 signature 36 54 3.9E-49 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CFK41_RS15120 63c12bb7622dc85e0822b85a02d6c519 626 PRINTS PR00742 Glycosyl hydrolase family 35 signature 91 110 3.9E-49 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CFK41_RS15120 63c12bb7622dc85e0822b85a02d6c519 626 PRINTS PR00742 Glycosyl hydrolase family 35 signature 268 283 3.9E-49 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CFK41_RS15120 63c12bb7622dc85e0822b85a02d6c519 626 PRINTS PR00742 Glycosyl hydrolase family 35 signature 565 581 3.9E-49 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CFK41_RS15120 63c12bb7622dc85e0822b85a02d6c519 626 PRINTS PR00742 Glycosyl hydrolase family 35 signature 232 247 3.9E-49 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CFK41_RS15120 63c12bb7622dc85e0822b85a02d6c519 626 PRINTS PR00742 Glycosyl hydrolase family 35 signature 294 310 3.9E-49 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CFK41_RS15120 63c12bb7622dc85e0822b85a02d6c519 626 Gene3D G3DSA:3.20.20.80 5 331 1.3E-70 T 28-03-2018 CFK41_RS15120 63c12bb7622dc85e0822b85a02d6c519 626 Gene3D G3DSA:2.60.120.260 535 604 7.3E-6 T 28-03-2018 IPR008979 Galactose-binding domain-like CFK41_RS15120 63c12bb7622dc85e0822b85a02d6c519 626 SUPERFAMILY SSF49785 471 611 6.8E-22 T 28-03-2018 IPR008979 Galactose-binding domain-like CFK41_RS15120 63c12bb7622dc85e0822b85a02d6c519 626 Gene3D G3DSA:2.60.120.260 355 512 3.5E-17 T 28-03-2018 IPR008979 Galactose-binding domain-like CFK41_RS09320 83199ee575c799a210230945f7b57cbd 418 Gene3D G3DSA:3.60.150.10 1 416 1.3E-131 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CFK41_RS09320 83199ee575c799a210230945f7b57cbd 418 Hamap MF_00300 Chorismate synthase [aroC]. 2 391 33.588 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CFK41_RS09320 83199ee575c799a210230945f7b57cbd 418 Pfam PF01264 Chorismate synthase 2 384 3.8E-113 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CFK41_RS09320 83199ee575c799a210230945f7b57cbd 418 SUPERFAMILY SSF103263 1 404 1.83E-127 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CFK41_RS09320 83199ee575c799a210230945f7b57cbd 418 PIRSF PIRSF001456 1 401 1.2E-119 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CFK41_RS09320 83199ee575c799a210230945f7b57cbd 418 ProSitePatterns PS00787 Chorismate synthase signature 1. 8 23 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CFK41_RS09320 83199ee575c799a210230945f7b57cbd 418 TIGRFAM TIGR00033 aroC: chorismate synthase 2 388 2.4E-119 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CFK41_RS01940 cd88fcb4759d81aaa53c88c803b97359 518 Pfam PF03611 PTS system sugar-specific permease component 15 425 1.7E-127 T 28-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 CFK41_RS14180 8d1d17a5b75752e97475faa5e0272561 272 Gene3D G3DSA:3.40.190.10 62 149 1.1E-18 T 28-03-2018 CFK41_RS14180 8d1d17a5b75752e97475faa5e0272561 272 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 1 36 1.3E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CFK41_RS14180 8d1d17a5b75752e97475faa5e0272561 272 SUPERFAMILY SSF53850 62 265 8.53E-32 T 28-03-2018 CFK41_RS14180 8d1d17a5b75752e97475faa5e0272561 272 SUPERFAMILY SSF46785 1 61 8.16E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS14180 8d1d17a5b75752e97475faa5e0272561 272 Pfam PF03466 LysR substrate binding domain 61 262 5.6E-37 T 28-03-2018 IPR005119 LysR, substrate-binding CFK41_RS14180 8d1d17a5b75752e97475faa5e0272561 272 Gene3D G3DSA:1.10.10.10 1 60 1.2E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS14180 8d1d17a5b75752e97475faa5e0272561 272 Gene3D G3DSA:3.40.190.10 150 240 1.2E-19 T 28-03-2018 CFK41_RS15535 bc829b4e41e9b32ab41a455182ebd785 712 SUPERFAMILY SSF53474 450 668 3.52E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS15535 bc829b4e41e9b32ab41a455182ebd785 712 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 34 431 2.4E-30 T 28-03-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 CFK41_RS15535 bc829b4e41e9b32ab41a455182ebd785 712 Pfam PF00326 Prolyl oligopeptidase family 496 688 9.7E-41 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CFK41_RS15535 bc829b4e41e9b32ab41a455182ebd785 712 Gene3D G3DSA:2.130.10.120 152 432 9.5E-24 T 28-03-2018 CFK41_RS15535 bc829b4e41e9b32ab41a455182ebd785 712 SUPERFAMILY SSF50993 21 441 3.14E-41 T 28-03-2018 CFK41_RS15535 bc829b4e41e9b32ab41a455182ebd785 712 Gene3D G3DSA:3.40.50.1820 8 135 1.0E-11 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS15535 bc829b4e41e9b32ab41a455182ebd785 712 Gene3D G3DSA:3.40.50.1820 433 693 5.0E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS15535 bc829b4e41e9b32ab41a455182ebd785 712 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 622 637 6.7E-32 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CFK41_RS15535 bc829b4e41e9b32ab41a455182ebd785 712 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 505 529 6.7E-32 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CFK41_RS15535 bc829b4e41e9b32ab41a455182ebd785 712 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 533 552 6.7E-32 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CFK41_RS15535 bc829b4e41e9b32ab41a455182ebd785 712 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 563 583 6.7E-32 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CFK41_RS15535 bc829b4e41e9b32ab41a455182ebd785 712 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 479 497 6.7E-32 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CFK41_RS15535 bc829b4e41e9b32ab41a455182ebd785 712 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 640 662 6.7E-32 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CFK41_RS03475 fdf2d0038f97e8f3d824d890246176e2 829 TIGRFAM TIGR03817 DECH_helic: helicase/secretion neighborhood putative DEAH-box helicase 23 827 0.0 T 28-03-2018 IPR022307 DEAD/DEAH-box helicase, putative, actinobacteria CFK41_RS03475 fdf2d0038f97e8f3d824d890246176e2 829 SUPERFAMILY SSF52540 315 466 1.7E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS03475 fdf2d0038f97e8f3d824d890246176e2 829 SUPERFAMILY SSF52540 70 239 1.7E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS03475 fdf2d0038f97e8f3d824d890246176e2 829 SMART SM00490 378 459 1.2E-12 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS03475 fdf2d0038f97e8f3d824d890246176e2 829 Pfam PF00270 DEAD/DEAH box helicase 62 237 3.9E-26 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CFK41_RS03475 fdf2d0038f97e8f3d824d890246176e2 829 SMART SM00487 55 267 1.2E-25 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CFK41_RS03475 fdf2d0038f97e8f3d824d890246176e2 829 Pfam PF09369 Domain of unknown function (DUF1998) 724 803 1.9E-19 T 28-03-2018 IPR018973 DEAD/DEAH-box helicase, putative CFK41_RS03475 fdf2d0038f97e8f3d824d890246176e2 829 Gene3D G3DSA:3.40.50.300 39 260 5.2E-35 T 28-03-2018 CFK41_RS03475 fdf2d0038f97e8f3d824d890246176e2 829 Pfam PF00271 Helicase conserved C-terminal domain 341 458 8.9E-13 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS03475 fdf2d0038f97e8f3d824d890246176e2 829 Gene3D G3DSA:3.40.50.300 328 486 4.3E-22 T 28-03-2018 CFK41_RS01890 59499469364ac88d824a9e8ec8e9cfd4 175 SUPERFAMILY SSF55729 7 148 2.79E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS01890 59499469364ac88d824a9e8ec8e9cfd4 175 Pfam PF00583 Acetyltransferase (GNAT) family 49 137 3.4E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS01890 59499469364ac88d824a9e8ec8e9cfd4 175 Gene3D G3DSA:3.40.630.30 1 166 5.6E-22 T 28-03-2018 CFK41_RS14255 097b6301effa1e6e9bb5352d0a81141b 718 SUPERFAMILY SSF52317 391 611 2.44E-18 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS14255 097b6301effa1e6e9bb5352d0a81141b 718 Gene3D G3DSA:3.20.20.80 10 314 1.6E-22 T 28-03-2018 CFK41_RS14255 097b6301effa1e6e9bb5352d0a81141b 718 SUPERFAMILY SSF51445 66 239 2.29E-6 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS14255 097b6301effa1e6e9bb5352d0a81141b 718 Gene3D G3DSA:3.40.50.880 373 607 8.0E-30 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS14255 097b6301effa1e6e9bb5352d0a81141b 718 Pfam PF14871 Hypothetical glycosyl hydrolase 6 44 171 3.4E-19 T 28-03-2018 IPR028212 Hypothetical glycosyl hydrolase 6 CFK41_RS08150 584a1395dabd2e1ecd6f60fae1438b0b 262 SUPERFAMILY SSF75217 83 261 1.52E-40 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CFK41_RS08150 584a1395dabd2e1ecd6f60fae1438b0b 262 SUPERFAMILY SSF88697 13 72 1.44E-8 T 28-03-2018 IPR015947 PUA-like domain CFK41_RS08150 584a1395dabd2e1ecd6f60fae1438b0b 262 PIRSF PIRSF015601 11 261 1.2E-43 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CFK41_RS08150 584a1395dabd2e1ecd6f60fae1438b0b 262 Gene3D G3DSA:3.40.1280.10 9 262 2.0E-63 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CFK41_RS08150 584a1395dabd2e1ecd6f60fae1438b0b 262 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 24 258 4.4E-29 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CFK41_RS08150 584a1395dabd2e1ecd6f60fae1438b0b 262 Pfam PF04452 RNA methyltransferase 26 256 6.6E-55 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CFK41_RS01625 c57c07cd267176e8fc3aa961c2a2f9a1 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 277 9.3E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01625 c57c07cd267176e8fc3aa961c2a2f9a1 284 SUPERFAMILY SSF161098 13 284 7.48E-61 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01625 c57c07cd267176e8fc3aa961c2a2f9a1 284 Gene3D G3DSA:1.10.3720.10 6 271 4.4E-40 T 28-03-2018 CFK41_RS08805 352ce1f0519de11b8c359299a9341ef1 225 Gene3D G3DSA:1.10.150.210 39 73 2.3E-21 T 28-03-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 CFK41_RS08805 352ce1f0519de11b8c359299a9341ef1 225 Gene3D G3DSA:3.30.70.260 4 38 0.019 T 28-03-2018 CFK41_RS08805 352ce1f0519de11b8c359299a9341ef1 225 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 12 214 1.1E-67 T 28-03-2018 CFK41_RS08805 352ce1f0519de11b8c359299a9341ef1 225 SUPERFAMILY SSF56784 15 214 1.07E-45 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS08805 352ce1f0519de11b8c359299a9341ef1 225 Pfam PF12710 haloacid dehalogenase-like hydrolase 18 184 4.4E-25 T 28-03-2018 CFK41_RS08805 352ce1f0519de11b8c359299a9341ef1 225 Gene3D G3DSA:3.40.50.1000 74 213 7.8E-28 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS08805 352ce1f0519de11b8c359299a9341ef1 225 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 16 186 2.8E-30 T 28-03-2018 CFK41_RS10770 b7b9fa5a7b47c64e25b0b795df472d72 259 Gene3D G3DSA:3.40.50.1220 12 249 3.8E-47 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CFK41_RS10770 b7b9fa5a7b47c64e25b0b795df472d72 259 SUPERFAMILY SSF52467 13 245 3.07E-58 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CFK41_RS10770 b7b9fa5a7b47c64e25b0b795df472d72 259 Pfam PF02146 Sir2 family 21 196 9.5E-32 T 28-03-2018 IPR003000 Sirtuin family GO:0070403 CFK41_RS10205 7e016204c9c5d2a77f8ceb445425219e 1203 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 60 1137 28.015 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CFK41_RS10205 7e016204c9c5d2a77f8ceb445425219e 1203 SMART SM01058 511 616 2.4E-42 T 28-03-2018 IPR003711 CarD-like/TRCF domain CFK41_RS10205 7e016204c9c5d2a77f8ceb445425219e 1203 SUPERFAMILY SSF52540 54 360 8.82E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS10205 7e016204c9c5d2a77f8ceb445425219e 1203 SMART SM00487 640 830 2.5E-24 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CFK41_RS10205 7e016204c9c5d2a77f8ceb445425219e 1203 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 180 1116 0.0 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CFK41_RS10205 7e016204c9c5d2a77f8ceb445425219e 1203 SUPERFAMILY SSF52540 822 1029 1.27E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS10205 7e016204c9c5d2a77f8ceb445425219e 1203 SMART SM00982 1043 1140 7.7E-31 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CFK41_RS10205 7e016204c9c5d2a77f8ceb445425219e 1203 Gene3D G3DSA:3.40.50.300 830 996 1.2E-24 T 28-03-2018 CFK41_RS10205 7e016204c9c5d2a77f8ceb445425219e 1203 Pfam PF03461 TRCF domain 1044 1129 2.0E-22 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CFK41_RS10205 7e016204c9c5d2a77f8ceb445425219e 1203 SUPERFAMILY SSF52540 565 823 3.23E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS10205 7e016204c9c5d2a77f8ceb445425219e 1203 SUPERFAMILY SSF143517 1030 1186 2.35E-31 T 28-03-2018 CFK41_RS10205 7e016204c9c5d2a77f8ceb445425219e 1203 SUPERFAMILY SSF141259 504 584 5.75E-15 T 28-03-2018 IPR003711 CarD-like/TRCF domain CFK41_RS10205 7e016204c9c5d2a77f8ceb445425219e 1203 Pfam PF00270 DEAD/DEAH box helicase 647 806 3.4E-14 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CFK41_RS10205 7e016204c9c5d2a77f8ceb445425219e 1203 Gene3D G3DSA:3.40.50.300 31 189 0.18 T 28-03-2018 CFK41_RS10205 7e016204c9c5d2a77f8ceb445425219e 1203 Pfam PF02559 CarD-like/TRCF domain 512 615 2.9E-28 T 28-03-2018 IPR003711 CarD-like/TRCF domain CFK41_RS10205 7e016204c9c5d2a77f8ceb445425219e 1203 Pfam PF00271 Helicase conserved C-terminal domain 850 949 3.7E-14 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS10205 7e016204c9c5d2a77f8ceb445425219e 1203 Gene3D G3DSA:3.40.50.300 318 826 2.8E-32 T 28-03-2018 CFK41_RS10205 7e016204c9c5d2a77f8ceb445425219e 1203 SMART SM00490 866 950 6.8E-17 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS13200 a2a937bd885ab8415b80a66aecd317bb 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 296 1.8E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS13200 a2a937bd885ab8415b80a66aecd317bb 305 SUPERFAMILY SSF160964 24 58 1.31E-5 T 28-03-2018 CFK41_RS13200 a2a937bd885ab8415b80a66aecd317bb 305 Gene3D G3DSA:1.10.3720.10 74 300 2.7E-44 T 28-03-2018 CFK41_RS13200 a2a937bd885ab8415b80a66aecd317bb 305 SUPERFAMILY SSF161098 66 291 7.72E-62 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS13200 a2a937bd885ab8415b80a66aecd317bb 305 Gene3D G3DSA:1.20.58.370 5 56 3.6E-9 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CFK41_RS10320 60c1201ece06526c4f0bb1ec00eff316 105 SMART SM00530 20 74 6.4E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CFK41_RS10320 60c1201ece06526c4f0bb1ec00eff316 105 SUPERFAMILY SSF47413 11 81 7.7E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS10320 60c1201ece06526c4f0bb1ec00eff316 105 Pfam PF13560 Helix-turn-helix domain 16 72 3.4E-9 T 28-03-2018 CFK41_RS10320 60c1201ece06526c4f0bb1ec00eff316 105 Gene3D G3DSA:1.10.260.40 6 92 5.2E-13 T 28-03-2018 CFK41_RS06620 a119f388928460d0ca71a630190ed83f 270 Hamap MF_00258 Glutamate racemase [murI]. 4 258 36.05 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CFK41_RS06620 a119f388928460d0ca71a630190ed83f 270 Gene3D G3DSA:3.40.50.1860 120 267 1.8E-43 T 28-03-2018 CFK41_RS06620 a119f388928460d0ca71a630190ed83f 270 SUPERFAMILY SSF53681 5 107 9.16E-35 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CFK41_RS06620 a119f388928460d0ca71a630190ed83f 270 SUPERFAMILY SSF53681 109 241 1.39E-34 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CFK41_RS06620 a119f388928460d0ca71a630190ed83f 270 TIGRFAM TIGR00067 glut_race: glutamate racemase 6 246 2.5E-69 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CFK41_RS06620 a119f388928460d0ca71a630190ed83f 270 Pfam PF01177 Asp/Glu/Hydantoin racemase 6 211 3.4E-35 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CFK41_RS06620 a119f388928460d0ca71a630190ed83f 270 Gene3D G3DSA:3.40.50.1860 2 119 4.7E-27 T 28-03-2018 CFK41_RS06620 a119f388928460d0ca71a630190ed83f 270 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 70 78 - T 28-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CFK41_RS06620 a119f388928460d0ca71a630190ed83f 270 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 179 189 - T 28-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CFK41_RS01740 856f4c2f608086e1018aa39431ce1d8b 422 Gene3D G3DSA:2.160.20.10 10 373 2.4E-91 T 28-03-2018 IPR012334 Pectin lyase fold CFK41_RS01740 856f4c2f608086e1018aa39431ce1d8b 422 SMART SM00710 216 237 1.6 T 28-03-2018 IPR006626 Parallel beta-helix repeat CFK41_RS01740 856f4c2f608086e1018aa39431ce1d8b 422 SMART SM00710 389 411 3400.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CFK41_RS01740 856f4c2f608086e1018aa39431ce1d8b 422 SMART SM00710 184 205 23.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CFK41_RS01740 856f4c2f608086e1018aa39431ce1d8b 422 SMART SM00710 243 264 2.9 T 28-03-2018 IPR006626 Parallel beta-helix repeat CFK41_RS01740 856f4c2f608086e1018aa39431ce1d8b 422 SMART SM00710 157 183 62.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CFK41_RS01740 856f4c2f608086e1018aa39431ce1d8b 422 Pfam PF00295 Glycosyl hydrolases family 28 99 298 1.4E-42 T 28-03-2018 IPR000743 Glycoside hydrolase, family 28 GO:0004650|GO:0005975 CFK41_RS01740 856f4c2f608086e1018aa39431ce1d8b 422 ProSitePatterns PS00502 Polygalacturonase active site. 223 237 - T 28-03-2018 IPR000743 Glycoside hydrolase, family 28 GO:0004650|GO:0005975 CFK41_RS01740 856f4c2f608086e1018aa39431ce1d8b 422 SUPERFAMILY SSF51126 16 363 1.65E-85 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CFK41_RS04970 b2df5d7c963844a4bef2d4b833a98fc5 303 TIGRFAM TIGR03446 mycothiol_Mca: mycothiol conjugate amidase Mca 12 294 4.0E-122 T 28-03-2018 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 CFK41_RS04970 b2df5d7c963844a4bef2d4b833a98fc5 303 SUPERFAMILY SSF102588 11 295 1.96E-68 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CFK41_RS04970 b2df5d7c963844a4bef2d4b833a98fc5 303 Hamap MF_01482 Mycothiol S-conjugate amidase [mca]. 15 295 48.58 T 28-03-2018 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 CFK41_RS04970 b2df5d7c963844a4bef2d4b833a98fc5 303 Gene3D G3DSA:3.40.50.10320 9 301 3.9E-68 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CFK41_RS04970 b2df5d7c963844a4bef2d4b833a98fc5 303 Pfam PF02585 GlcNAc-PI de-N-acetylase 16 162 1.5E-23 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CFK41_RS09275 9af2226d3d24399cb790259b7515bdca 184 Pfam PF13671 AAA domain 12 133 1.4E-7 T 28-03-2018 CFK41_RS09275 9af2226d3d24399cb790259b7515bdca 184 SUPERFAMILY SSF52540 5 171 1.5E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS09275 9af2226d3d24399cb790259b7515bdca 184 Gene3D G3DSA:3.40.50.300 1 174 1.3E-15 T 28-03-2018 CFK41_RS05500 7c3c2c80ccb5b257aeed6cc08bd875a0 253 SMART SM01134 73 234 8.6E-56 T 28-03-2018 CFK41_RS05500 7c3c2c80ccb5b257aeed6cc08bd875a0 253 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CFK41_RS05500 7c3c2c80ccb5b257aeed6cc08bd875a0 253 SUPERFAMILY SSF46785 4 62 1.07E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS05500 7c3c2c80ccb5b257aeed6cc08bd875a0 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 3.9E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CFK41_RS05500 7c3c2c80ccb5b257aeed6cc08bd875a0 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 3.9E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CFK41_RS05500 7c3c2c80ccb5b257aeed6cc08bd875a0 253 Gene3D G3DSA:3.40.50.1360 73 239 2.8E-34 T 28-03-2018 CFK41_RS05500 7c3c2c80ccb5b257aeed6cc08bd875a0 253 Pfam PF08220 DeoR-like helix-turn-helix domain 6 56 2.8E-15 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CFK41_RS05500 7c3c2c80ccb5b257aeed6cc08bd875a0 253 SUPERFAMILY SSF100950 74 234 2.3E-25 T 28-03-2018 CFK41_RS05500 7c3c2c80ccb5b257aeed6cc08bd875a0 253 Gene3D G3DSA:1.10.10.10 1 62 3.9E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS05500 7c3c2c80ccb5b257aeed6cc08bd875a0 253 SMART SM00420 6 58 8.6E-14 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CFK41_RS05500 7c3c2c80ccb5b257aeed6cc08bd875a0 253 Pfam PF00455 DeoR C terminal sensor domain 75 232 1.4E-41 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CFK41_RS04405 4f4f80d9a4af2ed25c9e892ac4bb7ea4 514 Gene3D G3DSA:2.40.10.10 199 279 1.4E-24 T 28-03-2018 CFK41_RS04405 4f4f80d9a4af2ed25c9e892ac4bb7ea4 514 SUPERFAMILY SSF50156 393 513 7.89E-19 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CFK41_RS04405 4f4f80d9a4af2ed25c9e892ac4bb7ea4 514 Gene3D G3DSA:2.40.10.10 280 412 1.9E-41 T 28-03-2018 CFK41_RS04405 4f4f80d9a4af2ed25c9e892ac4bb7ea4 514 PRINTS PR00834 HtrA/DegQ protease family signature 261 281 2.4E-33 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CFK41_RS04405 4f4f80d9a4af2ed25c9e892ac4bb7ea4 514 PRINTS PR00834 HtrA/DegQ protease family signature 458 470 2.4E-33 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CFK41_RS04405 4f4f80d9a4af2ed25c9e892ac4bb7ea4 514 PRINTS PR00834 HtrA/DegQ protease family signature 303 327 2.4E-33 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CFK41_RS04405 4f4f80d9a4af2ed25c9e892ac4bb7ea4 514 PRINTS PR00834 HtrA/DegQ protease family signature 371 388 2.4E-33 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CFK41_RS04405 4f4f80d9a4af2ed25c9e892ac4bb7ea4 514 PRINTS PR00834 HtrA/DegQ protease family signature 240 252 2.4E-33 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CFK41_RS04405 4f4f80d9a4af2ed25c9e892ac4bb7ea4 514 SMART SM00228 422 500 2.2E-8 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CFK41_RS04405 4f4f80d9a4af2ed25c9e892ac4bb7ea4 514 Gene3D G3DSA:2.30.42.10 420 513 6.2E-18 T 28-03-2018 CFK41_RS04405 4f4f80d9a4af2ed25c9e892ac4bb7ea4 514 SUPERFAMILY SSF50494 204 417 7.7E-55 T 28-03-2018 IPR009003 Peptidase S1, PA clan CFK41_RS04405 4f4f80d9a4af2ed25c9e892ac4bb7ea4 514 Pfam PF13180 PDZ domain 423 509 2.4E-14 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CFK41_RS04405 4f4f80d9a4af2ed25c9e892ac4bb7ea4 514 Pfam PF13365 Trypsin-like peptidase domain 231 378 1.4E-34 T 28-03-2018 CFK41_RS04250 23ed44c26668f17124abda817dd7e985 477 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 352 372 - T 28-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site CFK41_RS04250 23ed44c26668f17124abda817dd7e985 477 Pfam PF12804 MobA-like NTP transferase domain 14 167 1.8E-26 T 28-03-2018 IPR025877 MobA-like NTP transferase CFK41_RS04250 23ed44c26668f17124abda817dd7e985 477 Gene3D G3DSA:3.60.110.10 208 473 2.4E-63 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CFK41_RS04250 23ed44c26668f17124abda817dd7e985 477 Gene3D G3DSA:3.90.550.10 6 207 6.6E-27 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS04250 23ed44c26668f17124abda817dd7e985 477 Pfam PF00795 Carbon-nitrogen hydrolase 214 462 1.4E-37 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CFK41_RS04250 23ed44c26668f17124abda817dd7e985 477 SUPERFAMILY SSF56317 214 470 9.03E-62 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CFK41_RS04250 23ed44c26668f17124abda817dd7e985 477 SUPERFAMILY SSF53448 12 204 1.65E-23 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS14055 02634b5d600113971074ba8f30f6725f 222 Pfam PF00072 Response regulator receiver domain 4 118 5.2E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS14055 02634b5d600113971074ba8f30f6725f 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.2E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS14055 02634b5d600113971074ba8f30f6725f 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.2E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS14055 02634b5d600113971074ba8f30f6725f 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.2E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS14055 02634b5d600113971074ba8f30f6725f 222 Gene3D G3DSA:3.40.50.2300 1 128 2.6E-36 T 28-03-2018 CFK41_RS14055 02634b5d600113971074ba8f30f6725f 222 SUPERFAMILY SSF52172 1 128 6.26E-35 T 28-03-2018 IPR011006 CheY-like superfamily CFK41_RS14055 02634b5d600113971074ba8f30f6725f 222 SMART SM00448 2 117 4.7E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS14055 02634b5d600113971074ba8f30f6725f 222 Gene3D G3DSA:1.10.10.10 129 219 4.2E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS14055 02634b5d600113971074ba8f30f6725f 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 209 4.8E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS14055 02634b5d600113971074ba8f30f6725f 222 SMART SM00421 152 209 4.3E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS14055 02634b5d600113971074ba8f30f6725f 222 SUPERFAMILY SSF46894 147 216 3.23E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CFK41_RS14125 bdf4975cef025e11407c909568b65dc2 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 247 1.6E-46 T 28-03-2018 CFK41_RS14125 bdf4975cef025e11407c909568b65dc2 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 4.6E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS14125 bdf4975cef025e11407c909568b65dc2 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 4.6E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS14125 bdf4975cef025e11407c909568b65dc2 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 4.6E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS14125 bdf4975cef025e11407c909568b65dc2 253 Gene3D G3DSA:3.40.50.720 2 37 3.3E-6 T 28-03-2018 CFK41_RS14125 bdf4975cef025e11407c909568b65dc2 253 Gene3D G3DSA:3.40.50.720 38 253 2.0E-49 T 28-03-2018 CFK41_RS14125 bdf4975cef025e11407c909568b65dc2 253 SUPERFAMILY SSF51735 2 250 1.3E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS14125 bdf4975cef025e11407c909568b65dc2 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.7E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS14125 bdf4975cef025e11407c909568b65dc2 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.7E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS14125 bdf4975cef025e11407c909568b65dc2 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.7E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS14125 bdf4975cef025e11407c909568b65dc2 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 1.7E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS14125 bdf4975cef025e11407c909568b65dc2 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 1.7E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS14125 bdf4975cef025e11407c909568b65dc2 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.7E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS14125 bdf4975cef025e11407c909568b65dc2 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CFK41_RS17080 a9fc2e8ab24619b158eeac8151479706 364 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 54 111 2.4E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CFK41_RS17080 a9fc2e8ab24619b158eeac8151479706 364 SUPERFAMILY SSF53850 136 352 1.07E-32 T 28-03-2018 CFK41_RS17080 a9fc2e8ab24619b158eeac8151479706 364 Gene3D G3DSA:3.40.190.10 137 225 6.2E-23 T 28-03-2018 CFK41_RS17080 a9fc2e8ab24619b158eeac8151479706 364 SUPERFAMILY SSF46785 53 161 2.12E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS17080 a9fc2e8ab24619b158eeac8151479706 364 Pfam PF03466 LysR substrate binding domain 137 349 3.2E-33 T 28-03-2018 IPR005119 LysR, substrate-binding CFK41_RS17080 a9fc2e8ab24619b158eeac8151479706 364 Gene3D G3DSA:1.10.10.10 51 133 2.0E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS17080 a9fc2e8ab24619b158eeac8151479706 364 Gene3D G3DSA:3.40.190.10 226 320 1.1E-11 T 28-03-2018 CFK41_RS09660 b9b02572135955367894cac6709c83d8 324 SUPERFAMILY SSF50129 4 134 7.54E-27 T 28-03-2018 IPR011032 GroES-like CFK41_RS09660 b9b02572135955367894cac6709c83d8 324 Pfam PF00107 Zinc-binding dehydrogenase 150 281 7.2E-16 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CFK41_RS09660 b9b02572135955367894cac6709c83d8 324 SUPERFAMILY SSF51735 116 277 8.61E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS09660 b9b02572135955367894cac6709c83d8 324 SMART SM00829 18 320 8.6E-7 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CFK41_RS09660 b9b02572135955367894cac6709c83d8 324 Gene3D G3DSA:3.40.50.720 141 264 1.0E-17 T 28-03-2018 CFK41_RS09660 b9b02572135955367894cac6709c83d8 324 Pfam PF16884 N-terminal domain of oxidoreductase 6 102 2.2E-23 T 28-03-2018 CFK41_RS09660 b9b02572135955367894cac6709c83d8 324 Gene3D G3DSA:3.90.180.10 1 140 4.4E-28 T 28-03-2018 CFK41_RS10345 5f77ca75841ac387f754b52fd66e279e 295 Gene3D G3DSA:3.40.190.80 165 292 7.2E-20 T 28-03-2018 CFK41_RS10345 5f77ca75841ac387f754b52fd66e279e 295 Gene3D G3DSA:3.30.540.10 11 164 3.8E-39 T 28-03-2018 CFK41_RS10345 5f77ca75841ac387f754b52fd66e279e 295 SUPERFAMILY SSF56655 17 256 1.3E-57 T 28-03-2018 CFK41_RS10345 5f77ca75841ac387f754b52fd66e279e 295 PRINTS PR00377 Inositol monophosphatase superfamily signature 74 90 1.4E-34 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CFK41_RS10345 5f77ca75841ac387f754b52fd66e279e 295 PRINTS PR00377 Inositol monophosphatase superfamily signature 102 118 1.4E-34 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CFK41_RS10345 5f77ca75841ac387f754b52fd66e279e 295 PRINTS PR00377 Inositol monophosphatase superfamily signature 199 220 1.4E-34 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CFK41_RS10345 5f77ca75841ac387f754b52fd66e279e 295 PRINTS PR00377 Inositol monophosphatase superfamily signature 150 173 1.4E-34 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CFK41_RS10345 5f77ca75841ac387f754b52fd66e279e 295 PRINTS PR00377 Inositol monophosphatase superfamily signature 230 254 1.4E-34 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CFK41_RS10345 5f77ca75841ac387f754b52fd66e279e 295 PRINTS PR00377 Inositol monophosphatase superfamily signature 52 72 1.4E-34 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CFK41_RS10345 5f77ca75841ac387f754b52fd66e279e 295 Pfam PF00459 Inositol monophosphatase family 17 275 1.3E-47 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CFK41_RS03705 2a9ebce99cd8ffe8cc1801379339fe67 370 SUPERFAMILY SSF52518 27 356 2.18E-83 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CFK41_RS03705 2a9ebce99cd8ffe8cc1801379339fe67 370 Gene3D G3DSA:3.40.50.970 1 354 2.0E-76 T 28-03-2018 CFK41_RS03705 2a9ebce99cd8ffe8cc1801379339fe67 370 Pfam PF00676 Dehydrogenase E1 component 37 314 5.0E-66 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CFK41_RS16305 ec7c71b30d5d894a2eda398acf9b2c2c 676 SUPERFAMILY SSF52317 395 599 6.71E-47 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS16305 ec7c71b30d5d894a2eda398acf9b2c2c 676 Pfam PF08532 Beta-galactosidase trimerisation domain 398 598 2.7E-50 T 28-03-2018 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CFK41_RS16305 ec7c71b30d5d894a2eda398acf9b2c2c 676 Pfam PF02449 Beta-galactosidase 16 382 4.0E-117 T 28-03-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CFK41_RS16305 ec7c71b30d5d894a2eda398acf9b2c2c 676 Gene3D G3DSA:2.60.40.1180 609 663 8.2E-11 T 28-03-2018 CFK41_RS16305 ec7c71b30d5d894a2eda398acf9b2c2c 676 SUPERFAMILY SSF51445 12 383 5.45E-89 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS16305 ec7c71b30d5d894a2eda398acf9b2c2c 676 Gene3D G3DSA:3.20.20.80 10 371 6.4E-76 T 28-03-2018 CFK41_RS16305 ec7c71b30d5d894a2eda398acf9b2c2c 676 Gene3D G3DSA:3.40.50.880 395 603 1.3E-56 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS16305 ec7c71b30d5d894a2eda398acf9b2c2c 676 Pfam PF08533 Beta-galactosidase C-terminal domain 610 663 5.8E-9 T 28-03-2018 IPR013739 Beta-galactosidase C-terminal GO:0004565|GO:0006012 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CFK41_RS16305 ec7c71b30d5d894a2eda398acf9b2c2c 676 PIRSF PIRSF001084 7 666 3.2E-203 T 28-03-2018 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CFK41_RS07685 09f6dd73341ef572792ae2599c9d528a 190 SUPERFAMILY SSF55811 57 179 1.35E-29 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CFK41_RS07685 09f6dd73341ef572792ae2599c9d528a 190 Gene3D G3DSA:3.90.79.10 52 187 1.2E-29 T 28-03-2018 CFK41_RS07685 09f6dd73341ef572792ae2599c9d528a 190 ProSitePatterns PS00893 Nudix box signature. 90 111 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CFK41_RS07685 09f6dd73341ef572792ae2599c9d528a 190 PRINTS PR00502 NUDIX hydrolase family signature 99 114 8.4E-8 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CFK41_RS07685 09f6dd73341ef572792ae2599c9d528a 190 PRINTS PR00502 NUDIX hydrolase family signature 85 99 8.4E-8 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CFK41_RS07685 09f6dd73341ef572792ae2599c9d528a 190 Pfam PF00293 NUDIX domain 58 167 2.3E-19 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CFK41_RS11255 448edd32f138c2bfdd663396c193d543 617 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 188 196 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CFK41_RS11255 448edd32f138c2bfdd663396c193d543 617 SMART SM00490 296 377 2.3E-32 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS11255 448edd32f138c2bfdd663396c193d543 617 Pfam PF00271 Helicase conserved C-terminal domain 268 377 1.2E-27 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS11255 448edd32f138c2bfdd663396c193d543 617 SUPERFAMILY SSF52540 109 395 1.53E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11255 448edd32f138c2bfdd663396c193d543 617 Gene3D G3DSA:3.40.50.300 260 394 8.8E-43 T 28-03-2018 CFK41_RS11255 448edd32f138c2bfdd663396c193d543 617 Pfam PF00270 DEAD/DEAH box helicase 56 225 3.0E-47 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CFK41_RS11255 448edd32f138c2bfdd663396c193d543 617 SMART SM00487 51 260 2.5E-55 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CFK41_RS11255 448edd32f138c2bfdd663396c193d543 617 Gene3D G3DSA:3.40.50.300 30 259 5.0E-57 T 28-03-2018 CFK41_RS04795 c96b31ff0a42cd82a234a0d40d690511 327 SUPERFAMILY SSF54637 76 191 2.94E-10 T 28-03-2018 IPR029069 HotDog domain CFK41_RS04795 c96b31ff0a42cd82a234a0d40d690511 327 Gene3D G3DSA:3.10.129.10 69 196 1.7E-23 T 28-03-2018 CFK41_RS04795 c96b31ff0a42cd82a234a0d40d690511 327 Pfam PF01575 MaoC like domain 197 287 5.9E-15 T 28-03-2018 IPR002539 MaoC-like domain CFK41_RS04795 c96b31ff0a42cd82a234a0d40d690511 327 SUPERFAMILY SSF54637 210 311 5.6E-18 T 28-03-2018 IPR029069 HotDog domain CFK41_RS04795 c96b31ff0a42cd82a234a0d40d690511 327 Gene3D G3DSA:3.10.129.10 197 327 7.7E-18 T 28-03-2018 CFK41_RS04525 88d1392cefcc62104aa9c20a693c761c 427 Gene3D G3DSA:1.10.530.10 272 427 2.1E-34 T 28-03-2018 CFK41_RS04525 88d1392cefcc62104aa9c20a693c761c 427 SUPERFAMILY SSF53955 345 426 1.8E-32 T 28-03-2018 IPR023346 Lysozyme-like domain CFK41_RS04525 88d1392cefcc62104aa9c20a693c761c 427 SMART SM01208 199 277 2.3E-25 T 28-03-2018 IPR011098 G5 domain CFK41_RS04525 88d1392cefcc62104aa9c20a693c761c 427 Pfam PF03990 Domain of unknown function (DUF348) 89 127 3.8E-7 T 28-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 CFK41_RS04525 88d1392cefcc62104aa9c20a693c761c 427 Pfam PF03990 Domain of unknown function (DUF348) 33 72 3.4E-7 T 28-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 CFK41_RS04525 88d1392cefcc62104aa9c20a693c761c 427 Gene3D G3DSA:2.20.230.10 198 271 8.0E-19 T 28-03-2018 CFK41_RS04525 88d1392cefcc62104aa9c20a693c761c 427 Pfam PF07501 G5 domain 202 276 7.0E-19 T 28-03-2018 IPR011098 G5 domain CFK41_RS04525 88d1392cefcc62104aa9c20a693c761c 427 Pfam PF06737 Transglycosylase-like domain 347 420 2.0E-34 T 28-03-2018 IPR010618 Transglycosylase-like CFK41_RS05180 61c28d322273f129b03b29bd7c418551 178 TIGRFAM TIGR03847 TIGR03847: conserved hypothetical protein 4 175 3.9E-66 T 28-03-2018 IPR021441 Protein of unknown function DUF3090 CFK41_RS05180 61c28d322273f129b03b29bd7c418551 178 Pfam PF11290 Protein of unknown function (DUF3090) 6 173 6.5E-60 T 28-03-2018 IPR021441 Protein of unknown function DUF3090 CFK41_RS07965 4e906f3e0ac8b9fe8313adf126b31d4e 214 Pfam PF03352 Methyladenine glycosylase 17 191 7.8E-62 T 28-03-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 CFK41_RS07965 4e906f3e0ac8b9fe8313adf126b31d4e 214 SUPERFAMILY SSF48150 13 194 8.63E-62 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CFK41_RS07965 4e906f3e0ac8b9fe8313adf126b31d4e 214 Gene3D G3DSA:1.10.340.30 12 194 2.5E-71 T 28-03-2018 CFK41_RS14605 f6232def283e366f30d12c48ef2af649 255 Pfam PF13309 HTH domain 189 250 1.8E-18 T 28-03-2018 CFK41_RS14605 f6232def283e366f30d12c48ef2af649 255 ProDom PD037769 DNA-BINDING YHEO UNCHARACTERIZED BACTERIA SIMILAR HI0575 CONTAINING TRANSCRIPTION REGULATOR HELIX-TURN-HELIX 50 151 3.0E-20 T 28-03-2018 IPR013559 YheO-like CFK41_RS14605 f6232def283e366f30d12c48ef2af649 255 Pfam PF08348 YheO-like PAS domain 49 159 3.9E-34 T 28-03-2018 IPR013559 YheO-like CFK41_RS14605 f6232def283e366f30d12c48ef2af649 255 Gene3D G3DSA:1.10.10.10 207 255 0.0015 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS06690 933a0c891fe54d21bada9aa5d00be435 331 SUPERFAMILY SSF50129 1 147 8.65E-34 T 28-03-2018 IPR011032 GroES-like CFK41_RS06690 933a0c891fe54d21bada9aa5d00be435 331 SMART SM00829 8 328 1.7E-33 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CFK41_RS06690 933a0c891fe54d21bada9aa5d00be435 331 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 89 9.2E-11 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CFK41_RS06690 933a0c891fe54d21bada9aa5d00be435 331 SUPERFAMILY SSF51735 115 295 4.71E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS06690 933a0c891fe54d21bada9aa5d00be435 331 Gene3D G3DSA:3.90.180.10 1 193 7.0E-55 T 28-03-2018 CFK41_RS06690 933a0c891fe54d21bada9aa5d00be435 331 Gene3D G3DSA:3.90.180.10 194 331 3.9E-14 T 28-03-2018 CFK41_RS06690 933a0c891fe54d21bada9aa5d00be435 331 Pfam PF13602 Zinc-binding dehydrogenase 185 328 1.4E-33 T 28-03-2018 CFK41_RS02825 1ec68666b7a5015abb13504f78be22f0 387 Gene3D G3DSA:3.60.21.10 1 65 2.5E-14 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CFK41_RS02825 1ec68666b7a5015abb13504f78be22f0 387 Gene3D G3DSA:3.60.21.10 66 276 1.6E-30 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CFK41_RS02825 1ec68666b7a5015abb13504f78be22f0 387 Pfam PF00149 Calcineurin-like phosphoesterase 1 96 7.3E-12 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CFK41_RS02825 1ec68666b7a5015abb13504f78be22f0 387 SUPERFAMILY SSF56300 1 315 3.12E-53 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CFK41_RS02825 1ec68666b7a5015abb13504f78be22f0 387 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 275 359 8.2E-11 T 28-03-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain CFK41_RS02825 1ec68666b7a5015abb13504f78be22f0 387 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 251 2.8E-52 T 28-03-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 CFK41_RS11220 561c49c2bf38ee6d174d3edd1d598be9 305 Pfam PF09296 NADH pyrophosphatase-like rudimentary NUDIX domain 37 131 1.6E-9 T 28-03-2018 IPR015375 NADH pyrophosphatase-like, N-terminal GO:0016787 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 CFK41_RS11220 561c49c2bf38ee6d174d3edd1d598be9 305 Gene3D G3DSA:3.90.79.10 166 305 9.4E-33 T 28-03-2018 CFK41_RS11220 561c49c2bf38ee6d174d3edd1d598be9 305 ProSitePatterns PS00893 Nudix box signature. 200 221 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CFK41_RS11220 561c49c2bf38ee6d174d3edd1d598be9 305 SUPERFAMILY SSF55811 118 298 4.06E-40 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CFK41_RS11220 561c49c2bf38ee6d174d3edd1d598be9 305 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 133 164 2.4E-6 T 28-03-2018 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 CFK41_RS11220 561c49c2bf38ee6d174d3edd1d598be9 305 Pfam PF00293 NUDIX domain 169 277 4.2E-21 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CFK41_RS04600 55b190c3a7dcb3e4fe1f6bef083a7c7a 117 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 112 1.3E-41 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04600 55b190c3a7dcb3e4fe1f6bef083a7c7a 117 ProSitePatterns PS00464 Ribosomal protein L22 signature. 88 112 - T 28-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04600 55b190c3a7dcb3e4fe1f6bef083a7c7a 117 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 115 28.306 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04600 55b190c3a7dcb3e4fe1f6bef083a7c7a 117 SUPERFAMILY SSF54843 1 115 2.22E-38 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CFK41_RS04600 55b190c3a7dcb3e4fe1f6bef083a7c7a 117 Pfam PF00237 Ribosomal protein L22p/L17e 5 112 5.3E-34 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CFK41_RS04600 55b190c3a7dcb3e4fe1f6bef083a7c7a 117 Gene3D G3DSA:3.90.470.10 1 117 8.4E-42 T 28-03-2018 CFK41_RS10330 415c05f17116059c42d90e488620e754 104 Gene3D G3DSA:1.10.10.10 1 100 3.5E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS10330 415c05f17116059c42d90e488620e754 104 SUPERFAMILY SSF46785 1 95 1.8E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS10330 415c05f17116059c42d90e488620e754 104 Pfam PF01638 HxlR-like helix-turn-helix 3 89 1.2E-20 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CFK41_RS06695 eeedb89868a7470c9ab5bf624b48781d 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 7.9E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS06695 eeedb89868a7470c9ab5bf624b48781d 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 7.9E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS06695 eeedb89868a7470c9ab5bf624b48781d 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 66 1.4E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS06695 eeedb89868a7470c9ab5bf624b48781d 204 SUPERFAMILY SSF46689 9 92 4.19E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS06695 eeedb89868a7470c9ab5bf624b48781d 204 Gene3D G3DSA:1.10.357.10 2 201 1.0E-22 T 28-03-2018 CFK41_RS06600 1bc722ca1517e0812e0039d3ade96075 619 Gene3D G3DSA:3.40.50.300 288 545 6.8E-7 T 28-03-2018 CFK41_RS06600 1bc722ca1517e0812e0039d3ade96075 619 Pfam PF04851 Type III restriction enzyme, res subunit 56 209 1.2E-12 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CFK41_RS06600 1bc722ca1517e0812e0039d3ade96075 619 SMART SM00487 53 238 9.9E-12 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CFK41_RS06600 1bc722ca1517e0812e0039d3ade96075 619 SUPERFAMILY SSF52540 171 243 3.55E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS06600 1bc722ca1517e0812e0039d3ade96075 619 SUPERFAMILY SSF52540 302 421 3.55E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS06600 1bc722ca1517e0812e0039d3ade96075 619 Gene3D G3DSA:3.40.50.300 52 218 3.7E-20 T 28-03-2018 CFK41_RS06600 1bc722ca1517e0812e0039d3ade96075 619 SUPERFAMILY SSF52540 54 221 3.26E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS10600 c9a7bf5c42f563ec02a16014098e5f79 57 Gene3D G3DSA:1.10.1220.10 9 51 1.1E-11 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CFK41_RS10600 c9a7bf5c42f563ec02a16014098e5f79 57 Pfam PF01402 Ribbon-helix-helix protein, copG family 15 51 9.5E-6 T 28-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CFK41_RS10600 c9a7bf5c42f563ec02a16014098e5f79 57 SUPERFAMILY SSF47598 11 53 2.97E-7 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CFK41_RS10740 e05fb718be02c413fa00b75140e1fac7 980 SUPERFAMILY SSF53383 15 447 2.42E-92 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS10740 e05fb718be02c413fa00b75140e1fac7 980 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 15 975 0.0 T 28-03-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CFK41_RS10740 e05fb718be02c413fa00b75140e1fac7 980 Gene3D G3DSA:3.90.1150.10 785 917 6.7E-42 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS10740 e05fb718be02c413fa00b75140e1fac7 980 Gene3D G3DSA:3.40.640.10 527 784 9.1E-39 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS10740 e05fb718be02c413fa00b75140e1fac7 980 Gene3D G3DSA:3.40.640.10 100 347 7.8E-34 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS10740 e05fb718be02c413fa00b75140e1fac7 980 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 6 979 23.543 T 28-03-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CFK41_RS10740 e05fb718be02c413fa00b75140e1fac7 980 SUPERFAMILY SSF53383 956 978 3.09E-97 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS10740 e05fb718be02c413fa00b75140e1fac7 980 SUPERFAMILY SSF53383 485 899 3.09E-97 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS10740 e05fb718be02c413fa00b75140e1fac7 980 Gene3D G3DSA:3.90.1150.10 348 450 5.9E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS10740 e05fb718be02c413fa00b75140e1fac7 980 Pfam PF02347 Glycine cleavage system P-protein 14 445 2.3E-155 T 28-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CFK41_RS10740 e05fb718be02c413fa00b75140e1fac7 980 Pfam PF02347 Glycine cleavage system P-protein 484 738 5.0E-11 T 28-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CFK41_RS07320 fe67f823a81f87b846cd19e0a0b6f9b3 258 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 61 255 6.8E-63 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CFK41_RS07320 fe67f823a81f87b846cd19e0a0b6f9b3 258 Pfam PF10370 Domain of unknown function (DUF2437) 1 55 2.6E-17 T 28-03-2018 IPR018833 Domain of unknown function DUF2437 CFK41_RS07320 fe67f823a81f87b846cd19e0a0b6f9b3 258 Gene3D G3DSA:3.90.850.10 33 258 3.2E-85 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CFK41_RS07320 fe67f823a81f87b846cd19e0a0b6f9b3 258 SUPERFAMILY SSF56529 53 256 4.19E-75 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CFK41_RS05560 a5c82fa513bb26cca201860b42bd696f 296 Gene3D G3DSA:3.40.50.300 6 296 2.5E-81 T 28-03-2018 CFK41_RS05560 a5c82fa513bb26cca201860b42bd696f 296 TIGRFAM TIGR03709 PPK2_rel_1: polyphosphate:nucleotide phosphotransferase, PPK2 family 22 287 3.1E-104 T 28-03-2018 IPR022300 Polyphosphate:nucleotide phosphotransferase, PPK2 GO:0006797|GO:0016776 CFK41_RS05560 a5c82fa513bb26cca201860b42bd696f 296 PIRSF PIRSF028756 6 294 8.7E-71 T 28-03-2018 IPR016898 Polyphosphate kinase 2 CFK41_RS05560 a5c82fa513bb26cca201860b42bd696f 296 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 47 273 2.7E-68 T 28-03-2018 IPR022488 Polyphosphate kinase-2-related CFK41_RS05560 a5c82fa513bb26cca201860b42bd696f 296 SUPERFAMILY SSF52540 82 272 1.06E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS14640 43666ef82d5b8d9afa941217e4632505 259 Pfam PF00583 Acetyltransferase (GNAT) family 116 222 3.7E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS14640 43666ef82d5b8d9afa941217e4632505 259 Gene3D G3DSA:3.40.630.30 82 252 1.6E-24 T 28-03-2018 CFK41_RS14640 43666ef82d5b8d9afa941217e4632505 259 SUPERFAMILY SSF55729 61 229 8.51E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS12315 af8a621f0f391d7871fb5d29232a9ef1 440 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 347 439 7.6E-26 T 28-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CFK41_RS12315 af8a621f0f391d7871fb5d29232a9ef1 440 Gene3D G3DSA:3.40.50.1100 37 150 1.0E-27 T 28-03-2018 CFK41_RS12315 af8a621f0f391d7871fb5d29232a9ef1 440 Gene3D G3DSA:3.40.50.1100 151 342 1.7E-40 T 28-03-2018 CFK41_RS12315 af8a621f0f391d7871fb5d29232a9ef1 440 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 25 310 1.5E-68 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CFK41_RS12315 af8a621f0f391d7871fb5d29232a9ef1 440 TIGRFAM TIGR02079 THD1: threonine dehydratase 16 439 8.1E-159 T 28-03-2018 IPR011820 L-threonine dehydratase biosynthetic IlvA GO:0004794 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CFK41_RS12315 af8a621f0f391d7871fb5d29232a9ef1 440 SUPERFAMILY SSF53686 14 384 6.68E-87 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CFK41_RS12315 af8a621f0f391d7871fb5d29232a9ef1 440 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 52 65 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CFK41_RS15465 05037babab8dbf2b70feb8430653bf91 329 SMART SM00870 4 321 8.3E-90 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CFK41_RS15465 05037babab8dbf2b70feb8430653bf91 329 Gene3D G3DSA:3.40.50.40 207 326 3.2E-22 T 28-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 CFK41_RS15465 05037babab8dbf2b70feb8430653bf91 329 PIRSF PIRSF001220 2 328 5.8E-74 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CFK41_RS15465 05037babab8dbf2b70feb8430653bf91 329 PRINTS PR00139 Asparaginase/glutaminase family signature 79 97 2.1E-14 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CFK41_RS15465 05037babab8dbf2b70feb8430653bf91 329 PRINTS PR00139 Asparaginase/glutaminase family signature 255 273 2.1E-14 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CFK41_RS15465 05037babab8dbf2b70feb8430653bf91 329 PRINTS PR00139 Asparaginase/glutaminase family signature 5 16 2.1E-14 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CFK41_RS15465 05037babab8dbf2b70feb8430653bf91 329 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 80 90 - T 28-03-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 CFK41_RS15465 05037babab8dbf2b70feb8430653bf91 329 SUPERFAMILY SSF53774 5 325 5.23E-78 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CFK41_RS15465 05037babab8dbf2b70feb8430653bf91 329 Gene3D G3DSA:3.40.50.1170 3 201 1.4E-44 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CFK41_RS15465 05037babab8dbf2b70feb8430653bf91 329 Pfam PF00710 Asparaginase, N-terminal 5 187 1.6E-47 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CFK41_RS15465 05037babab8dbf2b70feb8430653bf91 329 PIRSF PIRSF500176 3 328 4.3E-72 T 28-03-2018 CFK41_RS04725 b33759738ea1228e58cbba466ec349e7 219 Gene3D G3DSA:3.90.1030.10 1 117 5.4E-42 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04725 b33759738ea1228e58cbba466ec349e7 219 Pfam PF01196 Ribosomal protein L17 21 116 2.5E-34 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04725 b33759738ea1228e58cbba466ec349e7 219 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04725 b33759738ea1228e58cbba466ec349e7 219 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 24.939 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04725 b33759738ea1228e58cbba466ec349e7 219 SUPERFAMILY SSF64263 1 119 4.32E-43 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04725 b33759738ea1228e58cbba466ec349e7 219 Gene3D G3DSA:3.40.10.10 123 217 2.6E-13 T 28-03-2018 IPR035451 Ada-like domain CFK41_RS04725 b33759738ea1228e58cbba466ec349e7 219 TIGRFAM TIGR00059 L17: ribosomal protein bL17 9 116 3.1E-37 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS03265 7be63d7872f3bb4628c7a8907da87d5b 344 Gene3D G3DSA:3.40.50.1980 172 342 3.7E-20 T 28-03-2018 CFK41_RS03265 7be63d7872f3bb4628c7a8907da87d5b 344 Gene3D G3DSA:3.40.50.1980 38 171 2.3E-23 T 28-03-2018 CFK41_RS03265 7be63d7872f3bb4628c7a8907da87d5b 344 SUPERFAMILY SSF53807 42 333 1.26E-39 T 28-03-2018 CFK41_RS03265 7be63d7872f3bb4628c7a8907da87d5b 344 Pfam PF01497 Periplasmic binding protein 59 309 1.6E-24 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CFK41_RS00725 43322b60d1aacf331bb1da153494f2e4 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 2.4E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS00725 43322b60d1aacf331bb1da153494f2e4 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 2.4E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS00725 43322b60d1aacf331bb1da153494f2e4 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 2.4E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS00725 43322b60d1aacf331bb1da153494f2e4 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 2.4E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS00725 43322b60d1aacf331bb1da153494f2e4 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 258 4.1E-33 T 28-03-2018 CFK41_RS00725 43322b60d1aacf331bb1da153494f2e4 263 SUPERFAMILY SSF51735 13 258 8.97E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS00725 43322b60d1aacf331bb1da153494f2e4 263 Gene3D G3DSA:3.40.50.720 2 260 9.6E-45 T 28-03-2018 CFK41_RS11375 48eb05631be83458bab03c88f913fc75 629 SUPERFAMILY SSF52540 327 576 4.0E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11375 48eb05631be83458bab03c88f913fc75 629 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS11375 48eb05631be83458bab03c88f913fc75 629 ProSitePatterns PS00211 ABC transporters family signature. 477 491 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS11375 48eb05631be83458bab03c88f913fc75 629 SMART SM00382 362 554 2.4E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS11375 48eb05631be83458bab03c88f913fc75 629 SMART SM00382 48 247 6.5E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS11375 48eb05631be83458bab03c88f913fc75 629 SUPERFAMILY SSF52540 19 269 4.91E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11375 48eb05631be83458bab03c88f913fc75 629 Pfam PF00005 ABC transporter 40 198 5.4E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS11375 48eb05631be83458bab03c88f913fc75 629 Pfam PF00005 ABC transporter 354 504 6.0E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS11375 48eb05631be83458bab03c88f913fc75 629 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 556 584 9.1E-4 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CFK41_RS11375 48eb05631be83458bab03c88f913fc75 629 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 249 292 9.5E-7 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CFK41_RS11375 48eb05631be83458bab03c88f913fc75 629 Gene3D G3DSA:3.40.50.300 16 317 3.4E-70 T 28-03-2018 CFK41_RS11375 48eb05631be83458bab03c88f913fc75 629 Gene3D G3DSA:3.40.50.300 324 611 4.1E-73 T 28-03-2018 CFK41_RS06555 457082d3f25a6625cf37e9636757f499 332 Gene3D G3DSA:3.40.630.30 22 157 1.7E-15 T 28-03-2018 CFK41_RS06555 457082d3f25a6625cf37e9636757f499 332 Pfam PF00583 Acetyltransferase (GNAT) family 57 123 1.6E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS06555 457082d3f25a6625cf37e9636757f499 332 Pfam PF00583 Acetyltransferase (GNAT) family 224 300 2.5E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS06555 457082d3f25a6625cf37e9636757f499 332 Gene3D G3DSA:3.40.630.30 162 320 2.8E-21 T 28-03-2018 CFK41_RS06555 457082d3f25a6625cf37e9636757f499 332 SUPERFAMILY SSF55729 144 309 1.08E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS06555 457082d3f25a6625cf37e9636757f499 332 SUPERFAMILY SSF55729 28 128 3.26E-15 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS11625 d5744e69161ed24a9653a4ab18f3e4d0 533 SMART SM00729 172 390 6.4E-59 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CFK41_RS11625 d5744e69161ed24a9653a4ab18f3e4d0 533 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 25 470 1.2E-140 T 28-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CFK41_RS11625 d5744e69161ed24a9653a4ab18f3e4d0 533 SUPERFAMILY SSF102114 157 398 1.27E-56 T 28-03-2018 CFK41_RS11625 d5744e69161ed24a9653a4ab18f3e4d0 533 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 176 196 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CFK41_RS11625 d5744e69161ed24a9653a4ab18f3e4d0 533 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 26 439 1.2E-127 T 28-03-2018 CFK41_RS11625 d5744e69161ed24a9653a4ab18f3e4d0 533 Pfam PF04055 Radical SAM superfamily 176 347 2.9E-29 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CFK41_RS11625 d5744e69161ed24a9653a4ab18f3e4d0 533 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 24 474 64.311 T 28-03-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 CFK41_RS11625 d5744e69161ed24a9653a4ab18f3e4d0 533 Gene3D G3DSA:3.80.30.20 169 402 4.4E-52 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CFK41_RS11625 d5744e69161ed24a9653a4ab18f3e4d0 533 Pfam PF00919 Uncharacterized protein family UPF0004 26 129 2.8E-24 T 28-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CFK41_RS01105 43600800d10dd17268ec663da5fcdd2f 159 Gene3D G3DSA:3.30.530.20 5 159 7.9E-19 T 28-03-2018 IPR023393 START-like domain CFK41_RS01105 43600800d10dd17268ec663da5fcdd2f 159 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 28 144 7.2E-9 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CFK41_RS01105 43600800d10dd17268ec663da5fcdd2f 159 SUPERFAMILY SSF55961 12 156 4.66E-18 T 28-03-2018 CFK41_RS03325 9d00963cd7514ab1106aac2db3e64758 228 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 221 4.0E-42 T 28-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CFK41_RS03325 9d00963cd7514ab1106aac2db3e64758 228 SUPERFAMILY SSF53448 2 220 1.6E-39 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS03325 9d00963cd7514ab1106aac2db3e64758 228 Gene3D G3DSA:3.90.550.10 2 228 6.3E-38 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS05930 9789f6334648e164914396fd15d3886b 162 SUPERFAMILY SSF89963 5 87 1.57E-28 T 28-03-2018 IPR007551 Protein of unknown function DUF520 CFK41_RS05930 9789f6334648e164914396fd15d3886b 162 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 3 162 26.037 T 28-03-2018 IPR007551 Protein of unknown function DUF520 CFK41_RS05930 9789f6334648e164914396fd15d3886b 162 Gene3D G3DSA:3.30.70.860 97 162 3.2E-30 T 28-03-2018 IPR035571 UPF0234/UPF0381 domain CFK41_RS05930 9789f6334648e164914396fd15d3886b 162 Gene3D G3DSA:3.30.70.990 12 96 6.2E-33 T 28-03-2018 IPR035570 UPF0234 N-terminal domain CFK41_RS05930 9789f6334648e164914396fd15d3886b 162 SUPERFAMILY SSF89963 90 162 1.57E-24 T 28-03-2018 IPR007551 Protein of unknown function DUF520 CFK41_RS05930 9789f6334648e164914396fd15d3886b 162 Pfam PF04461 Protein of unknown function (DUF520) 4 162 5.8E-62 T 28-03-2018 IPR007551 Protein of unknown function DUF520 CFK41_RS04885 47b90f620978b92b029c36f509264d1b 169 SUPERFAMILY SSF54211 45 169 2.05E-42 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CFK41_RS04885 47b90f620978b92b029c36f509264d1b 169 Gene3D G3DSA:3.30.230.10 39 169 1.6E-46 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CFK41_RS04885 47b90f620978b92b029c36f509264d1b 169 ProSitePatterns PS00360 Ribosomal protein S9 signature. 107 125 - T 28-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 CFK41_RS04885 47b90f620978b92b029c36f509264d1b 169 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 39 169 32.454 T 28-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid CFK41_RS04885 47b90f620978b92b029c36f509264d1b 169 Pfam PF00380 Ribosomal protein S9/S16 48 169 2.0E-41 T 28-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 CFK41_RS04050 9c3cc14d12702f54dcb5f7696c42ab3d 502 Pfam PF01235 Sodium:alanine symporter family 69 470 6.5E-130 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CFK41_RS04050 9c3cc14d12702f54dcb5f7696c42ab3d 502 PRINTS PR00175 Sodium/alanine symporter signature 427 447 1.2E-45 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CFK41_RS04050 9c3cc14d12702f54dcb5f7696c42ab3d 502 PRINTS PR00175 Sodium/alanine symporter signature 104 126 1.2E-45 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CFK41_RS04050 9c3cc14d12702f54dcb5f7696c42ab3d 502 PRINTS PR00175 Sodium/alanine symporter signature 203 221 1.2E-45 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CFK41_RS04050 9c3cc14d12702f54dcb5f7696c42ab3d 502 PRINTS PR00175 Sodium/alanine symporter signature 231 250 1.2E-45 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CFK41_RS04050 9c3cc14d12702f54dcb5f7696c42ab3d 502 PRINTS PR00175 Sodium/alanine symporter signature 367 389 1.2E-45 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CFK41_RS04050 9c3cc14d12702f54dcb5f7696c42ab3d 502 PRINTS PR00175 Sodium/alanine symporter signature 322 340 1.2E-45 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CFK41_RS04050 9c3cc14d12702f54dcb5f7696c42ab3d 502 TIGRFAM TIGR00835 agcS: amino acid carrier protein 24 458 1.4E-118 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CFK41_RS06920 b2ad1b5b4b50462ed97c52ab58854407 364 SMART SM00387 242 361 2.7E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS06920 b2ad1b5b4b50462ed97c52ab58854407 364 Gene3D G3DSA:1.10.287.130 122 190 1.2E-18 T 28-03-2018 CFK41_RS06920 b2ad1b5b4b50462ed97c52ab58854407 364 Pfam PF00512 His Kinase A (phospho-acceptor) domain 132 196 2.0E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CFK41_RS06920 b2ad1b5b4b50462ed97c52ab58854407 364 SMART SM00304 79 131 2.1E-13 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CFK41_RS06920 b2ad1b5b4b50462ed97c52ab58854407 364 SUPERFAMILY SSF47384 115 196 1.53E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CFK41_RS06920 b2ad1b5b4b50462ed97c52ab58854407 364 SUPERFAMILY SSF158472 79 128 2.62E-11 T 28-03-2018 CFK41_RS06920 b2ad1b5b4b50462ed97c52ab58854407 364 Pfam PF00672 HAMP domain 80 127 1.2E-12 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CFK41_RS06920 b2ad1b5b4b50462ed97c52ab58854407 364 Gene3D G3DSA:3.30.565.10 191 360 2.7E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS06920 b2ad1b5b4b50462ed97c52ab58854407 364 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 243 359 3.7E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS06920 b2ad1b5b4b50462ed97c52ab58854407 364 SMART SM00388 132 196 2.1E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CFK41_RS06920 b2ad1b5b4b50462ed97c52ab58854407 364 SUPERFAMILY SSF55874 185 358 2.62E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS06920 b2ad1b5b4b50462ed97c52ab58854407 364 PRINTS PR00344 Bacterial sensor protein C-terminal signature 281 295 1.5E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS06920 b2ad1b5b4b50462ed97c52ab58854407 364 PRINTS PR00344 Bacterial sensor protein C-terminal signature 345 358 1.5E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS06920 b2ad1b5b4b50462ed97c52ab58854407 364 PRINTS PR00344 Bacterial sensor protein C-terminal signature 314 332 1.5E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS06920 b2ad1b5b4b50462ed97c52ab58854407 364 PRINTS PR00344 Bacterial sensor protein C-terminal signature 299 309 1.5E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS00680 10ab6b9af6a687be9233b82b93233a9d 420 Hamap MF_00372 Imidazolonepropionase [hutI]. 3 419 40.473 T 28-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CFK41_RS00680 10ab6b9af6a687be9233b82b93233a9d 420 SUPERFAMILY SSF51338 379 418 1.88E-14 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS00680 10ab6b9af6a687be9233b82b93233a9d 420 SUPERFAMILY SSF51338 29 72 1.88E-14 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS00680 10ab6b9af6a687be9233b82b93233a9d 420 SUPERFAMILY SSF51556 71 378 8.17E-58 T 28-03-2018 IPR032466 Metal-dependent hydrolase CFK41_RS00680 10ab6b9af6a687be9233b82b93233a9d 420 Gene3D G3DSA:2.30.40.10 19 86 3.8E-20 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS00680 10ab6b9af6a687be9233b82b93233a9d 420 Pfam PF01979 Amidohydrolase family 69 394 4.6E-11 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CFK41_RS00680 10ab6b9af6a687be9233b82b93233a9d 420 Gene3D G3DSA:3.20.20.140 87 378 2.8E-43 T 28-03-2018 CFK41_RS03725 68bf4d4be65d68fbaaf7701274f1606d 137 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 10 137 15.148 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CFK41_RS03725 68bf4d4be65d68fbaaf7701274f1606d 137 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 11 132 5.0E-20 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CFK41_RS02740 163a8234438eeccae5b53a18284c0481 408 SUPERFAMILY SSF51735 5 162 1.3E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS02740 163a8234438eeccae5b53a18284c0481 408 Gene3D G3DSA:3.40.50.720 5 153 1.3E-31 T 28-03-2018 CFK41_RS02740 163a8234438eeccae5b53a18284c0481 408 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 146 287 6.3E-6 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CFK41_RS02740 163a8234438eeccae5b53a18284c0481 408 Gene3D G3DSA:3.30.360.10 154 401 4.4E-41 T 28-03-2018 CFK41_RS02740 163a8234438eeccae5b53a18284c0481 408 SUPERFAMILY SSF55347 140 225 1.96E-26 T 28-03-2018 CFK41_RS02740 163a8234438eeccae5b53a18284c0481 408 SUPERFAMILY SSF55347 261 311 1.96E-26 T 28-03-2018 CFK41_RS02740 163a8234438eeccae5b53a18284c0481 408 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 11 129 2.1E-18 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS10940 a35c84307312382bb6a9f2278e6f8080 259 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 67 1.0E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS10940 a35c84307312382bb6a9f2278e6f8080 259 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 67 83 1.0E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS10940 a35c84307312382bb6a9f2278e6f8080 259 SUPERFAMILY SSF46785 24 101 4.02E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS10940 a35c84307312382bb6a9f2278e6f8080 259 Gene3D G3DSA:1.10.10.10 18 99 2.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS10940 a35c84307312382bb6a9f2278e6f8080 259 SMART SM00895 122 248 1.5E-14 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS10940 a35c84307312382bb6a9f2278e6f8080 259 SUPERFAMILY SSF48008 120 253 1.67E-21 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS10940 a35c84307312382bb6a9f2278e6f8080 259 Pfam PF00392 Bacterial regulatory proteins, gntR family 34 90 5.1E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS10940 a35c84307312382bb6a9f2278e6f8080 259 Gene3D G3DSA:1.20.120.530 102 259 2.4E-24 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS10940 a35c84307312382bb6a9f2278e6f8080 259 Pfam PF07729 FCD domain 122 247 1.3E-17 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS10940 a35c84307312382bb6a9f2278e6f8080 259 SMART SM00345 34 97 5.7E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS09745 bd9ea56ca95b2a3c6a7691765e4544bc 261 SUPERFAMILY SSF51366 4 261 8.63E-75 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CFK41_RS09745 bd9ea56ca95b2a3c6a7691765e4544bc 261 Pfam PF00977 Histidine biosynthesis protein 6 245 7.8E-82 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 CFK41_RS09745 bd9ea56ca95b2a3c6a7691765e4544bc 261 Gene3D G3DSA:3.20.20.70 5 257 2.4E-61 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS09745 bd9ea56ca95b2a3c6a7691765e4544bc 261 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 261 46.372 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CFK41_RS09745 bd9ea56ca95b2a3c6a7691765e4544bc 261 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 3 261 5.0E-107 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CFK41_RS03665 7280f3f06b53beb285e0d365798763d1 430 SUPERFAMILY SSF51735 5 154 4.1E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS03665 7280f3f06b53beb285e0d365798763d1 430 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 121 3.7E-15 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS03665 7280f3f06b53beb285e0d365798763d1 430 SUPERFAMILY SSF55347 129 278 1.14E-6 T 28-03-2018 CFK41_RS03665 7280f3f06b53beb285e0d365798763d1 430 Gene3D G3DSA:3.40.50.720 2 133 1.1E-29 T 28-03-2018 CFK41_RS03665 7280f3f06b53beb285e0d365798763d1 430 Gene3D G3DSA:3.30.360.10 134 400 1.1E-44 T 28-03-2018 CFK41_RS05190 f2dee51fe1ddb2a23a11bbfad6503b7e 257 SMART SM00450 119 219 7.2E-7 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS05190 f2dee51fe1ddb2a23a11bbfad6503b7e 257 SUPERFAMILY SSF52821 99 233 3.84E-22 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS05190 f2dee51fe1ddb2a23a11bbfad6503b7e 257 Gene3D G3DSA:3.40.250.10 107 225 5.3E-17 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS05980 a38e86dfc761afcfc72f01d8fdfd07a4 273 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 4 271 2.2E-53 T 28-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 CFK41_RS05980 a38e86dfc761afcfc72f01d8fdfd07a4 273 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 6 265 1.1E-16 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS05980 a38e86dfc761afcfc72f01d8fdfd07a4 273 Gene3D G3DSA:3.60.10.10 1 273 1.2E-45 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS05980 a38e86dfc761afcfc72f01d8fdfd07a4 273 SUPERFAMILY SSF56219 3 272 4.06E-60 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS09980 71520eb63a23d6d14b251e05233586ec 443 Pfam PF13367 Protease prsW family 125 328 1.5E-47 T 28-03-2018 IPR026898 Protease PrsW GO:0008233 CFK41_RS15080 32c52c4ea0c73852ee9831374977b005 385 Pfam PF14606 GDSL-like Lipase/Acylhydrolase family 201 380 3.1E-20 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CFK41_RS15080 32c52c4ea0c73852ee9831374977b005 385 SUPERFAMILY SSF52266 196 380 3.36E-23 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CFK41_RS15080 32c52c4ea0c73852ee9831374977b005 385 Gene3D G3DSA:3.40.50.1110 197 383 3.1E-25 T 28-03-2018 CFK41_RS10465 d1c415b30e7bd126656d5182c24909f4 291 Hamap MF_00158 Pantothenate synthetase [panC]. 16 286 34.188 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CFK41_RS10465 d1c415b30e7bd126656d5182c24909f4 291 Pfam PF02569 Pantoate-beta-alanine ligase 18 283 6.0E-82 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CFK41_RS10465 d1c415b30e7bd126656d5182c24909f4 291 Gene3D G3DSA:3.30.1300.10 187 290 5.7E-21 T 28-03-2018 CFK41_RS10465 d1c415b30e7bd126656d5182c24909f4 291 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 35 80 3.7E-7 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CFK41_RS10465 d1c415b30e7bd126656d5182c24909f4 291 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 19 284 2.6E-73 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CFK41_RS10465 d1c415b30e7bd126656d5182c24909f4 291 SUPERFAMILY SSF52374 15 284 2.34E-80 T 28-03-2018 CFK41_RS10465 d1c415b30e7bd126656d5182c24909f4 291 Gene3D G3DSA:3.40.50.620 6 185 3.5E-62 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS07215 7b280d864c7f15de5707e0189d696052 505 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 406 425 3.3E-9 T 28-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CFK41_RS07215 7b280d864c7f15de5707e0189d696052 505 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 363 378 3.3E-9 T 28-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CFK41_RS07215 7b280d864c7f15de5707e0189d696052 505 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 152 172 3.3E-9 T 28-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CFK41_RS07215 7b280d864c7f15de5707e0189d696052 505 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 28 47 3.3E-9 T 28-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CFK41_RS07215 7b280d864c7f15de5707e0189d696052 505 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 92 424 1.4E-59 T 28-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 CFK41_RS07215 7b280d864c7f15de5707e0189d696052 505 Gene3D G3DSA:3.40.640.10 104 378 5.4E-59 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS07215 7b280d864c7f15de5707e0189d696052 505 Gene3D G3DSA:3.90.1150.10 379 493 2.1E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS07215 7b280d864c7f15de5707e0189d696052 505 Gene3D G3DSA:1.20.1650.10 19 92 2.7E-12 T 28-03-2018 CFK41_RS07215 7b280d864c7f15de5707e0189d696052 505 SUPERFAMILY SSF53383 25 490 2.34E-115 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS02610 e623e3705a1dc35cfd7a7c1e9761d0a3 302 Gene3D G3DSA:3.40.50.720 1 292 3.7E-60 T 28-03-2018 CFK41_RS02610 e623e3705a1dc35cfd7a7c1e9761d0a3 302 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 3.3E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02610 e623e3705a1dc35cfd7a7c1e9761d0a3 302 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 3.3E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02610 e623e3705a1dc35cfd7a7c1e9761d0a3 302 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 3.3E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02610 e623e3705a1dc35cfd7a7c1e9761d0a3 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 6.7E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02610 e623e3705a1dc35cfd7a7c1e9761d0a3 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 6.7E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02610 e623e3705a1dc35cfd7a7c1e9761d0a3 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 6.7E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02610 e623e3705a1dc35cfd7a7c1e9761d0a3 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 6.7E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02610 e623e3705a1dc35cfd7a7c1e9761d0a3 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 6.7E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02610 e623e3705a1dc35cfd7a7c1e9761d0a3 302 Pfam PF00106 short chain dehydrogenase 16 206 2.2E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02610 e623e3705a1dc35cfd7a7c1e9761d0a3 302 SUPERFAMILY SSF51735 12 209 8.72E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS00120 bfbe200e4e9289dcb743724f4c68ab96 395 SUPERFAMILY SSF88946 3 84 8.24E-11 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS00120 bfbe200e4e9289dcb743724f4c68ab96 395 Pfam PF04542 Sigma-70 region 2 8 72 1.9E-8 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS00120 bfbe200e4e9289dcb743724f4c68ab96 395 SUPERFAMILY SSF88659 104 160 1.5E-9 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS00120 bfbe200e4e9289dcb743724f4c68ab96 395 Gene3D G3DSA:1.10.1740.10 2 72 1.3E-12 T 28-03-2018 CFK41_RS00120 bfbe200e4e9289dcb743724f4c68ab96 395 Pfam PF08281 Sigma-70, region 4 108 158 2.9E-7 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS00120 bfbe200e4e9289dcb743724f4c68ab96 395 Gene3D G3DSA:1.10.10.10 73 162 1.5E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS09985 c81326af80c847ca2ae77e2864babe74 185 Pfam PF01230 HIT domain 61 152 5.5E-11 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CFK41_RS09985 c81326af80c847ca2ae77e2864babe74 185 Gene3D G3DSA:3.30.428.10 13 185 4.8E-38 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CFK41_RS09985 c81326af80c847ca2ae77e2864babe74 185 SUPERFAMILY SSF54197 23 177 1.18E-38 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CFK41_RS14195 adb686c880090e83334100bd9be9acd6 285 Pfam PF00248 Aldo/keto reductase family 30 200 6.8E-35 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS14195 adb686c880090e83334100bd9be9acd6 285 Pfam PF00248 Aldo/keto reductase family 206 267 5.5E-8 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS14195 adb686c880090e83334100bd9be9acd6 285 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 131 148 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CFK41_RS14195 adb686c880090e83334100bd9be9acd6 285 PRINTS PR00069 Aldo-keto reductase signature 202 226 2.9E-39 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS14195 adb686c880090e83334100bd9be9acd6 285 PRINTS PR00069 Aldo-keto reductase signature 99 117 2.9E-39 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS14195 adb686c880090e83334100bd9be9acd6 285 PRINTS PR00069 Aldo-keto reductase signature 165 194 2.9E-39 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS14195 adb686c880090e83334100bd9be9acd6 285 PRINTS PR00069 Aldo-keto reductase signature 43 67 2.9E-39 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS14195 adb686c880090e83334100bd9be9acd6 285 PRINTS PR00069 Aldo-keto reductase signature 131 148 2.9E-39 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS14195 adb686c880090e83334100bd9be9acd6 285 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 47 64 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CFK41_RS14195 adb686c880090e83334100bd9be9acd6 285 PIRSF PIRSF000097 8 282 2.5E-68 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS14195 adb686c880090e83334100bd9be9acd6 285 Gene3D G3DSA:3.20.20.100 10 282 7.9E-90 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS14195 adb686c880090e83334100bd9be9acd6 285 SUPERFAMILY SSF51430 16 275 3.01E-86 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS14195 adb686c880090e83334100bd9be9acd6 285 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 235 250 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CFK41_RS03080 1645cd2b1e5060fc23b1ac18edac5b51 695 Gene3D G3DSA:3.30.300.30 543 657 5.9E-23 T 28-03-2018 CFK41_RS03080 1645cd2b1e5060fc23b1ac18edac5b51 695 Pfam PF00501 AMP-binding enzyme 110 549 4.9E-92 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CFK41_RS03080 1645cd2b1e5060fc23b1ac18edac5b51 695 Gene3D G3DSA:3.40.50.980 287 450 1.4E-35 T 28-03-2018 CFK41_RS03080 1645cd2b1e5060fc23b1ac18edac5b51 695 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 38 678 5.6E-237 T 28-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 CFK41_RS03080 1645cd2b1e5060fc23b1ac18edac5b51 695 Gene3D G3DSA:2.30.38.10 451 542 3.3E-14 T 28-03-2018 CFK41_RS03080 1645cd2b1e5060fc23b1ac18edac5b51 695 SUPERFAMILY SSF56801 41 679 1.44E-157 T 28-03-2018 CFK41_RS03080 1645cd2b1e5060fc23b1ac18edac5b51 695 ProSitePatterns PS00455 Putative AMP-binding domain signature. 281 292 - T 28-03-2018 IPR020845 AMP-binding, conserved site CFK41_RS03080 1645cd2b1e5060fc23b1ac18edac5b51 695 Pfam PF13193 AMP-binding enzyme C-terminal domain 558 637 3.4E-19 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CFK41_RS03080 1645cd2b1e5060fc23b1ac18edac5b51 695 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 39 103 1.8E-13 T 28-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 CFK41_RS03080 1645cd2b1e5060fc23b1ac18edac5b51 695 Gene3D G3DSA:3.40.50.980 96 286 8.5E-49 T 28-03-2018 CFK41_RS07880 30a4fbfcd7a3ee5076f9f5c4b348879e 607 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 119 495 8.9E-60 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CFK41_RS07880 30a4fbfcd7a3ee5076f9f5c4b348879e 607 SUPERFAMILY SSF53850 77 583 4.11E-89 T 28-03-2018 CFK41_RS07880 30a4fbfcd7a3ee5076f9f5c4b348879e 607 PIRSF PIRSF002741 52 570 2.2E-57 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CFK41_RS07880 30a4fbfcd7a3ee5076f9f5c4b348879e 607 Gene3D G3DSA:3.40.190.10 230 336 3.2E-15 T 28-03-2018 CFK41_RS07880 30a4fbfcd7a3ee5076f9f5c4b348879e 607 Gene3D G3DSA:3.90.76.10 81 229 1.7E-24 T 28-03-2018 CFK41_RS07880 30a4fbfcd7a3ee5076f9f5c4b348879e 607 Gene3D G3DSA:3.10.105.10 337 565 1.2E-41 T 28-03-2018 CFK41_RS08360 13af4ad3154edc2170654efc0e5b574b 158 Pfam PF02566 OsmC-like protein 46 144 1.5E-5 T 28-03-2018 IPR003718 OsmC/Ohr family CFK41_RS08360 13af4ad3154edc2170654efc0e5b574b 158 SUPERFAMILY SSF82784 20 146 9.16E-14 T 28-03-2018 IPR003718 OsmC/Ohr family CFK41_RS08360 13af4ad3154edc2170654efc0e5b574b 158 Gene3D G3DSA:3.30.300.20 17 152 1.8E-15 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CFK41_RS11345 edcdabc593b2fd9e4e9a1872c1ef5160 391 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 246 259 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CFK41_RS11345 edcdabc593b2fd9e4e9a1872c1ef5160 391 SUPERFAMILY SSF53383 18 390 1.06E-76 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS11345 edcdabc593b2fd9e4e9a1872c1ef5160 391 Gene3D G3DSA:3.40.640.10 60 282 2.7E-36 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS11345 edcdabc593b2fd9e4e9a1872c1ef5160 391 TIGRFAM TIGR03539 DapC_actino: succinyldiaminopimelate transaminase 20 388 1.3E-157 T 28-03-2018 IPR019880 Succinyldiaminopimelate transaminase, DapC, actinobacteria CFK41_RS11345 edcdabc593b2fd9e4e9a1872c1ef5160 391 Gene3D G3DSA:3.90.1150.10 283 391 7.7E-22 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS11345 edcdabc593b2fd9e4e9a1872c1ef5160 391 Pfam PF00155 Aminotransferase class I and II 42 388 9.5E-40 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CFK41_RS05375 cc0ad135c97df5b478df20c4aac0eb31 229 Pfam PF01872 RibD C-terminal domain 28 203 3.1E-18 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CFK41_RS05375 cc0ad135c97df5b478df20c4aac0eb31 229 SUPERFAMILY SSF53597 29 215 7.55E-22 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CFK41_RS05375 cc0ad135c97df5b478df20c4aac0eb31 229 Gene3D G3DSA:3.40.430.10 26 208 9.4E-24 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CFK41_RS13190 4fa9500e212ee51d8990206a2b572104 403 Pfam PF00155 Aminotransferase class I and II 33 382 4.1E-49 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CFK41_RS13190 4fa9500e212ee51d8990206a2b572104 403 Gene3D G3DSA:3.90.1150.10 280 403 1.4E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS13190 4fa9500e212ee51d8990206a2b572104 403 Gene3D G3DSA:3.40.640.10 52 279 1.9E-53 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS13190 4fa9500e212ee51d8990206a2b572104 403 SUPERFAMILY SSF53383 6 399 1.29E-93 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS05040 02a23b74cfd5cf80413d53f7b2266272 665 Gene3D G3DSA:3.40.50.410 41 231 1.4E-29 T 28-03-2018 IPR002035 von Willebrand factor, type A CFK41_RS05040 02a23b74cfd5cf80413d53f7b2266272 665 Pfam PF13519 von Willebrand factor type A domain 42 159 4.1E-13 T 28-03-2018 IPR002035 von Willebrand factor, type A CFK41_RS05040 02a23b74cfd5cf80413d53f7b2266272 665 SMART SM00327 38 228 5.6E-14 T 28-03-2018 IPR002035 von Willebrand factor, type A CFK41_RS05040 02a23b74cfd5cf80413d53f7b2266272 665 SUPERFAMILY SSF53300 42 229 1.75E-21 T 28-03-2018 IPR002035 von Willebrand factor, type A CFK41_RS16480 0f8ef986cccf00c1d321e57010d9cb8f 362 SUPERFAMILY SSF51735 1 147 3.95E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS16480 0f8ef986cccf00c1d321e57010d9cb8f 362 Gene3D G3DSA:3.30.360.10 134 342 1.2E-28 T 28-03-2018 CFK41_RS16480 0f8ef986cccf00c1d321e57010d9cb8f 362 Gene3D G3DSA:3.40.50.720 1 133 4.3E-30 T 28-03-2018 CFK41_RS16480 0f8ef986cccf00c1d321e57010d9cb8f 362 SUPERFAMILY SSF55347 127 287 3.11E-28 T 28-03-2018 CFK41_RS16480 0f8ef986cccf00c1d321e57010d9cb8f 362 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 116 2.1E-16 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS00425 92f9fa3b44ddf6831ef39cbfdf5b0095 334 Gene3D G3DSA:3.40.50.2300 64 165 1.4E-22 T 28-03-2018 CFK41_RS00425 92f9fa3b44ddf6831ef39cbfdf5b0095 334 Pfam PF13377 Periplasmic binding protein-like domain 169 327 6.2E-32 T 28-03-2018 CFK41_RS00425 92f9fa3b44ddf6831ef39cbfdf5b0095 334 SUPERFAMILY SSF47413 4 55 1.43E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS00425 92f9fa3b44ddf6831ef39cbfdf5b0095 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 51 2.2E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS00425 92f9fa3b44ddf6831ef39cbfdf5b0095 334 Gene3D G3DSA:1.10.10.60 3 20 0.0021 T 28-03-2018 CFK41_RS00425 92f9fa3b44ddf6831ef39cbfdf5b0095 334 Gene3D G3DSA:3.40.50.2300 166 330 1.3E-38 T 28-03-2018 CFK41_RS00425 92f9fa3b44ddf6831ef39cbfdf5b0095 334 SMART SM00354 5 75 2.2E-17 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS00425 92f9fa3b44ddf6831ef39cbfdf5b0095 334 SUPERFAMILY SSF53822 66 329 4.52E-52 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS00425 92f9fa3b44ddf6831ef39cbfdf5b0095 334 Gene3D G3DSA:1.10.260.40 21 63 1.9E-18 T 28-03-2018 CFK41_RS16675 0e3dca603e93f5fa2cfde80eb58b9876 286 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 13 224 3.1E-41 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CFK41_RS16675 0e3dca603e93f5fa2cfde80eb58b9876 286 Gene3D G3DSA:3.40.1010.10 10 136 7.8E-33 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CFK41_RS16675 0e3dca603e93f5fa2cfde80eb58b9876 286 SUPERFAMILY SSF53790 8 248 6.54E-65 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CFK41_RS16675 0e3dca603e93f5fa2cfde80eb58b9876 286 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 11 248 1.0E-75 T 28-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CFK41_RS16675 0e3dca603e93f5fa2cfde80eb58b9876 286 Gene3D G3DSA:3.30.950.10 137 264 1.5E-28 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CFK41_RS08800 c6be37500a19f30273e2d66cd900eba6 175 SMART SM00855 10 123 7.8E-9 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CFK41_RS08800 c6be37500a19f30273e2d66cd900eba6 175 PIRSF PIRSF000709 4 92 2.3E-4 T 28-03-2018 CFK41_RS08800 c6be37500a19f30273e2d66cd900eba6 175 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 11 76 4.8E-10 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CFK41_RS08800 c6be37500a19f30273e2d66cd900eba6 175 SUPERFAMILY SSF53254 9 158 9.59E-22 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CFK41_RS08800 c6be37500a19f30273e2d66cd900eba6 175 Gene3D G3DSA:3.40.50.1240 1 175 2.2E-28 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CFK41_RS02795 78a7e5b5328d391481852eb8f96f8302 567 Gene3D G3DSA:3.40.1800.10 363 443 5.8E-6 T 28-03-2018 CFK41_RS04430 b36c1a2230b91e4888e58d3fc3316db3 557 Pfam PF01808 AICARFT/IMPCHase bienzyme 140 479 3.6E-102 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CFK41_RS04430 b36c1a2230b91e4888e58d3fc3316db3 557 Gene3D G3DSA:3.40.140.20 246 391 5.9E-45 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CFK41_RS04430 b36c1a2230b91e4888e58d3fc3316db3 557 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 9 557 40.431 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CFK41_RS04430 b36c1a2230b91e4888e58d3fc3316db3 557 Gene3D G3DSA:3.40.140.20 392 547 3.8E-53 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CFK41_RS04430 b36c1a2230b91e4888e58d3fc3316db3 557 SUPERFAMILY SSF53927 241 557 9.33E-110 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CFK41_RS04430 b36c1a2230b91e4888e58d3fc3316db3 557 Gene3D G3DSA:3.40.50.1380 1 197 2.2E-66 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CFK41_RS04430 b36c1a2230b91e4888e58d3fc3316db3 557 SMART SM00798 140 480 9.1E-149 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CFK41_RS04430 b36c1a2230b91e4888e58d3fc3316db3 557 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 10 557 1.6E-162 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CFK41_RS04430 b36c1a2230b91e4888e58d3fc3316db3 557 PIRSF PIRSF000414 3 557 2.8E-187 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CFK41_RS04430 b36c1a2230b91e4888e58d3fc3316db3 557 SUPERFAMILY SSF52335 9 199 1.25E-63 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CFK41_RS04430 b36c1a2230b91e4888e58d3fc3316db3 557 SMART SM00851 21 135 2.9E-52 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CFK41_RS04430 b36c1a2230b91e4888e58d3fc3316db3 557 Pfam PF02142 MGS-like domain 21 135 1.5E-27 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CFK41_RS00510 fe2295df777fcfa539e0bcd27eceb473 134 Gene3D G3DSA:1.10.10.10 1 134 9.8E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS00510 fe2295df777fcfa539e0bcd27eceb473 134 SUPERFAMILY SSF46785 2 128 3.11E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS00510 fe2295df777fcfa539e0bcd27eceb473 134 Pfam PF12802 MarR family 20 77 6.8E-8 T 28-03-2018 CFK41_RS00510 fe2295df777fcfa539e0bcd27eceb473 134 SMART SM00347 15 114 7.3E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS02500 ce850e1b219c1fc7bff14800f2c75c2a 564 SUPERFAMILY SSF48230 44 260 1.01E-15 T 28-03-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 CFK41_RS02500 ce850e1b219c1fc7bff14800f2c75c2a 564 Pfam PF07940 Heparinase II/III-like protein 292 500 2.5E-18 T 28-03-2018 IPR012480 Heparinase II/III-like GO:0016829 CFK41_RS02500 ce850e1b219c1fc7bff14800f2c75c2a 564 Pfam PF16889 Heparinase II/III N-terminus 45 274 8.7E-14 T 28-03-2018 IPR031680 Heparin-sulfate lyase, N-terminal MetaCyc: PWY-7651 CFK41_RS02500 ce850e1b219c1fc7bff14800f2c75c2a 564 Gene3D G3DSA:1.50.10.100 15 314 8.9E-20 T 28-03-2018 CFK41_RS07635 04e710119045c3f1f9232be4781fe3f6 342 Pfam PF12872 OST-HTH/LOTUS domain 267 337 7.1E-11 T 28-03-2018 IPR025605 OST-HTH/LOTUS domain CFK41_RS07635 04e710119045c3f1f9232be4781fe3f6 342 Gene3D G3DSA:3.40.50.1010 1 184 6.6E-32 T 28-03-2018 IPR029060 PIN domain-like CFK41_RS07635 04e710119045c3f1f9232be4781fe3f6 342 Pfam PF01936 NYN domain 8 180 9.7E-24 T 28-03-2018 IPR021139 NYN domain, limkain-b1-type CFK41_RS15035 176266760b13ea8cc05263e0951cd142 188 Gene3D G3DSA:1.10.260.40 3 71 5.6E-19 T 28-03-2018 CFK41_RS15035 176266760b13ea8cc05263e0951cd142 188 SUPERFAMILY SSF51182 91 170 2.35E-14 T 28-03-2018 IPR011051 RmlC-like cupin domain CFK41_RS15035 176266760b13ea8cc05263e0951cd142 188 Pfam PF01381 Helix-turn-helix 16 70 2.3E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CFK41_RS15035 176266760b13ea8cc05263e0951cd142 188 Gene3D G3DSA:2.60.120.10 72 188 1.0E-13 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CFK41_RS15035 176266760b13ea8cc05263e0951cd142 188 Pfam PF07883 Cupin domain 117 173 3.9E-10 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CFK41_RS15035 176266760b13ea8cc05263e0951cd142 188 SMART SM00530 15 70 1.3E-17 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CFK41_RS15035 176266760b13ea8cc05263e0951cd142 188 SUPERFAMILY SSF47413 12 76 5.63E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS16175 bcb4355fc4c93b5448ba3de4d33c6cc2 178 SUPERFAMILY SSF50891 2 176 2.34E-58 T 28-03-2018 IPR029000 Cyclophilin-like domain CFK41_RS16175 bcb4355fc4c93b5448ba3de4d33c6cc2 178 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 134 149 3.2E-20 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CFK41_RS16175 bcb4355fc4c93b5448ba3de4d33c6cc2 178 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 121 133 3.2E-20 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CFK41_RS16175 bcb4355fc4c93b5448ba3de4d33c6cc2 178 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 57 69 3.2E-20 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CFK41_RS16175 bcb4355fc4c93b5448ba3de4d33c6cc2 178 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 16 31 3.2E-20 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CFK41_RS16175 bcb4355fc4c93b5448ba3de4d33c6cc2 178 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 106 121 3.2E-20 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CFK41_RS16175 bcb4355fc4c93b5448ba3de4d33c6cc2 178 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 52 69 - T 28-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 CFK41_RS16175 bcb4355fc4c93b5448ba3de4d33c6cc2 178 PIRSF PIRSF001467 1 178 2.6E-51 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 CFK41_RS16175 bcb4355fc4c93b5448ba3de4d33c6cc2 178 Gene3D G3DSA:2.40.100.10 2 178 1.2E-60 T 28-03-2018 IPR029000 Cyclophilin-like domain CFK41_RS16175 bcb4355fc4c93b5448ba3de4d33c6cc2 178 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 3 176 1.4E-44 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CFK41_RS03565 a366e97a11450e5c75e6d17fc6914c74 210 Pfam PF08768 Domain of unknown function (DUF1794) 13 209 1.3E-19 T 28-03-2018 IPR014878 Domain of unknown function DUF1794 CFK41_RS03565 a366e97a11450e5c75e6d17fc6914c74 210 Gene3D G3DSA:2.40.128.20 1 210 1.4E-29 T 28-03-2018 IPR012674 Calycin CFK41_RS03565 a366e97a11450e5c75e6d17fc6914c74 210 SUPERFAMILY SSF50814 8 104 1.26E-9 T 28-03-2018 IPR012674 Calycin CFK41_RS03565 a366e97a11450e5c75e6d17fc6914c74 210 SUPERFAMILY SSF50814 131 188 1.26E-9 T 28-03-2018 IPR012674 Calycin CFK41_RS12040 6181c3c547d566a34e8451741738e717 410 PRINTS PR00173 Glutamate-aspartate symporter signature 281 307 4.1E-6 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CFK41_RS12040 6181c3c547d566a34e8451741738e717 410 PRINTS PR00173 Glutamate-aspartate symporter signature 344 364 4.1E-6 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CFK41_RS12040 6181c3c547d566a34e8451741738e717 410 PRINTS PR00173 Glutamate-aspartate symporter signature 13 33 4.1E-6 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CFK41_RS12040 6181c3c547d566a34e8451741738e717 410 Gene3D G3DSA:1.10.3860.10 9 393 3.4E-66 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CFK41_RS12040 6181c3c547d566a34e8451741738e717 410 Pfam PF00375 Sodium:dicarboxylate symporter family 15 389 2.7E-75 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CFK41_RS12040 6181c3c547d566a34e8451741738e717 410 SUPERFAMILY SSF118215 15 389 1.96E-78 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CFK41_RS02265 f9ae3d05a8dd0b36e95e33b8a49f4f7d 282 Pfam PF00483 Nucleotidyl transferase 24 248 7.3E-23 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CFK41_RS02265 f9ae3d05a8dd0b36e95e33b8a49f4f7d 282 SUPERFAMILY SSF53448 23 278 2.05E-39 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS02265 f9ae3d05a8dd0b36e95e33b8a49f4f7d 282 Gene3D G3DSA:3.90.550.10 15 282 2.1E-43 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS02515 de960c5a1864c2e77f2dc4efee88bdd0 125 SMART SM00448 2 112 2.9E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS02515 de960c5a1864c2e77f2dc4efee88bdd0 125 Pfam PF00072 Response regulator receiver domain 5 112 2.4E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS02515 de960c5a1864c2e77f2dc4efee88bdd0 125 SUPERFAMILY SSF52172 2 119 1.08E-33 T 28-03-2018 IPR011006 CheY-like superfamily CFK41_RS02515 de960c5a1864c2e77f2dc4efee88bdd0 125 Gene3D G3DSA:3.40.50.2300 2 124 6.3E-33 T 28-03-2018 CFK41_RS06945 69ac40222eac84b58a49197341d29e0a 760 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 516 721 1.1E-16 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CFK41_RS06945 69ac40222eac84b58a49197341d29e0a 760 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 516 753 4.7E-31 T 28-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 CFK41_RS06945 69ac40222eac84b58a49197341d29e0a 760 Pfam PF02358 Trehalose-phosphatase 520 725 5.1E-29 T 28-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 CFK41_RS06945 69ac40222eac84b58a49197341d29e0a 760 SUPERFAMILY SSF56784 516 753 2.15E-28 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS06945 69ac40222eac84b58a49197341d29e0a 760 Gene3D G3DSA:3.40.50.2000 268 461 4.7E-39 T 28-03-2018 CFK41_RS06945 69ac40222eac84b58a49197341d29e0a 760 Pfam PF00982 Glycosyltransferase family 20 15 476 3.7E-139 T 28-03-2018 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 CFK41_RS06945 69ac40222eac84b58a49197341d29e0a 760 Gene3D G3DSA:3.40.50.1000 514 760 8.0E-19 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS06945 69ac40222eac84b58a49197341d29e0a 760 Gene3D G3DSA:3.40.50.2000 12 267 4.6E-80 T 28-03-2018 CFK41_RS06945 69ac40222eac84b58a49197341d29e0a 760 SUPERFAMILY SSF53756 15 475 5.9E-133 T 28-03-2018 CFK41_RS14265 7b0fe1b123664db9cc4fc23c57677c88 240 Gene3D G3DSA:1.10.10.10 20 101 6.3E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS14265 7b0fe1b123664db9cc4fc23c57677c88 240 Pfam PF07729 FCD domain 105 227 6.0E-19 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS14265 7b0fe1b123664db9cc4fc23c57677c88 240 SUPERFAMILY SSF48008 102 234 1.41E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS14265 7b0fe1b123664db9cc4fc23c57677c88 240 SUPERFAMILY SSF46785 29 109 1.27E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS14265 7b0fe1b123664db9cc4fc23c57677c88 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 34 93 8.7E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS14265 7b0fe1b123664db9cc4fc23c57677c88 240 Gene3D G3DSA:1.20.120.530 102 240 3.8E-24 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS14265 7b0fe1b123664db9cc4fc23c57677c88 240 SMART SM00345 37 95 2.0E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS14265 7b0fe1b123664db9cc4fc23c57677c88 240 SMART SM00895 105 228 2.4E-15 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS05380 0a1c9b3a6e5038734abf097570100f80 256 Pfam PF05988 Bacterial protein of unknown function (DUF899) 11 213 9.7E-56 T 28-03-2018 IPR010296 Protein of unknown function DUF899, thioredoxin-like CFK41_RS12890 3fe1ee9db7b3cbef2f1045e832b1f229 369 Pfam PF00480 ROK family 88 262 6.7E-22 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CFK41_RS12890 3fe1ee9db7b3cbef2f1045e832b1f229 369 Gene3D G3DSA:1.10.10.10 18 80 9.0E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS12890 3fe1ee9db7b3cbef2f1045e832b1f229 369 Gene3D G3DSA:3.30.420.40 82 223 4.6E-29 T 28-03-2018 CFK41_RS12890 3fe1ee9db7b3cbef2f1045e832b1f229 369 Pfam PF12802 MarR family 19 63 1.2E-6 T 28-03-2018 CFK41_RS12890 3fe1ee9db7b3cbef2f1045e832b1f229 369 SUPERFAMILY SSF53067 86 355 4.86E-34 T 28-03-2018 CFK41_RS12890 3fe1ee9db7b3cbef2f1045e832b1f229 369 Gene3D G3DSA:3.30.420.40 268 357 2.1E-9 T 28-03-2018 CFK41_RS12890 3fe1ee9db7b3cbef2f1045e832b1f229 369 SUPERFAMILY SSF46785 17 78 1.01E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS12890 3fe1ee9db7b3cbef2f1045e832b1f229 369 Gene3D G3DSA:3.30.420.40 224 267 2.0E-14 T 28-03-2018 CFK41_RS16425 8de5b63e1c23d023ea05fe9de3387ab4 308 Gene3D G3DSA:1.10.3720.10 26 299 6.4E-35 T 28-03-2018 CFK41_RS16425 8de5b63e1c23d023ea05fe9de3387ab4 308 SUPERFAMILY SSF161098 25 308 5.1E-56 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS16425 8de5b63e1c23d023ea05fe9de3387ab4 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 300 1.6E-10 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS05310 32cf1cda1bc1948472c83b57e7f6bec8 198 SMART SM00563 29 138 1.7E-14 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CFK41_RS05310 32cf1cda1bc1948472c83b57e7f6bec8 198 SUPERFAMILY SSF69593 20 134 2.88E-17 T 28-03-2018 CFK41_RS05310 32cf1cda1bc1948472c83b57e7f6bec8 198 Pfam PF01553 Acyltransferase 22 134 8.9E-10 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CFK41_RS05310 32cf1cda1bc1948472c83b57e7f6bec8 198 Gene3D G3DSA:3.40.1130.10 16 155 9.7E-18 T 28-03-2018 CFK41_RS09115 0473cd121f46310cf9fe01dea6c9f9a9 206 SMART SM00448 4 118 3.3E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS09115 0473cd121f46310cf9fe01dea6c9f9a9 206 ProSitePatterns PS00622 LuxR-type HTH domain signature. 160 187 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS09115 0473cd121f46310cf9fe01dea6c9f9a9 206 SMART SM00421 143 200 2.5E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS09115 0473cd121f46310cf9fe01dea6c9f9a9 206 SUPERFAMILY SSF52172 1 130 1.42E-32 T 28-03-2018 IPR011006 CheY-like superfamily CFK41_RS09115 0473cd121f46310cf9fe01dea6c9f9a9 206 Gene3D G3DSA:3.40.50.2300 3 127 2.1E-36 T 28-03-2018 CFK41_RS09115 0473cd121f46310cf9fe01dea6c9f9a9 206 Gene3D G3DSA:1.10.10.10 128 206 1.4E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS09115 0473cd121f46310cf9fe01dea6c9f9a9 206 SUPERFAMILY SSF46894 143 206 5.44E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CFK41_RS09115 0473cd121f46310cf9fe01dea6c9f9a9 206 Pfam PF00072 Response regulator receiver domain 7 118 1.2E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS09115 0473cd121f46310cf9fe01dea6c9f9a9 206 Pfam PF00196 Bacterial regulatory proteins, luxR family 145 200 4.3E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS09115 0473cd121f46310cf9fe01dea6c9f9a9 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 7.5E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS09115 0473cd121f46310cf9fe01dea6c9f9a9 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 7.5E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS09115 0473cd121f46310cf9fe01dea6c9f9a9 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 7.5E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS06235 25caa4fbbf32b3b25593981d77e818dd 701 Pfam PF13641 Glycosyltransferase like family 2 206 462 1.4E-36 T 28-03-2018 CFK41_RS06235 25caa4fbbf32b3b25593981d77e818dd 701 SUPERFAMILY SSF53448 207 345 3.38E-22 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS06235 25caa4fbbf32b3b25593981d77e818dd 701 SUPERFAMILY SSF53448 378 463 3.38E-22 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS06235 25caa4fbbf32b3b25593981d77e818dd 701 Gene3D G3DSA:3.90.550.10 192 503 1.7E-14 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS16125 463428dc62d693d95a6d51d248e37c6a 260 Pfam PF00756 Putative esterase 44 251 1.3E-27 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CFK41_RS16125 463428dc62d693d95a6d51d248e37c6a 260 Gene3D G3DSA:3.40.50.1820 5 256 1.6E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS16125 463428dc62d693d95a6d51d248e37c6a 260 SUPERFAMILY SSF53474 9 255 2.89E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS03175 a29e0f5d62b87908a1472a0c229c18bf 509 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 1 409 18.889 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CFK41_RS03175 a29e0f5d62b87908a1472a0c229c18bf 509 SUPERFAMILY SSF69075 315 412 1.03E-9 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CFK41_RS03175 a29e0f5d62b87908a1472a0c229c18bf 509 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 179 302 8.3E-8 T 28-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CFK41_RS03175 a29e0f5d62b87908a1472a0c229c18bf 509 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 316 410 1.4E-14 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CFK41_RS03175 a29e0f5d62b87908a1472a0c229c18bf 509 SUPERFAMILY SSF51735 173 301 1.05E-12 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS03175 a29e0f5d62b87908a1472a0c229c18bf 509 Gene3D G3DSA:3.40.50.720 167 310 1.5E-13 T 28-03-2018 CFK41_RS03175 a29e0f5d62b87908a1472a0c229c18bf 509 SUPERFAMILY SSF69742 2 161 3.79E-28 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CFK41_RS03175 a29e0f5d62b87908a1472a0c229c18bf 509 Gene3D G3DSA:1.10.1200.70 327 412 2.6E-12 T 28-03-2018 CFK41_RS03175 a29e0f5d62b87908a1472a0c229c18bf 509 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 7 161 3.8E-30 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CFK41_RS03175 a29e0f5d62b87908a1472a0c229c18bf 509 PIRSF PIRSF000445 1 425 2.1E-82 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CFK41_RS01695 0cedb6caa19de724b6a06d485135156a 196 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 18 187 1.5E-25 T 28-03-2018 IPR017520 Conserved hypothetical protein CHP03086 CFK41_RS01695 0cedb6caa19de724b6a06d485135156a 196 SUPERFAMILY SSF109854 9 138 3.11E-9 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CFK41_RS01695 0cedb6caa19de724b6a06d485135156a 196 Gene3D G3DSA:1.20.120.450 11 137 1.7E-11 T 28-03-2018 CFK41_RS11950 311ab63055c7b0d2e6e2b025bd5190bf 112 SUPERFAMILY SSF54913 1 112 3.61E-38 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CFK41_RS11950 311ab63055c7b0d2e6e2b025bd5190bf 112 SMART SM00938 4 105 1.5E-48 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CFK41_RS11950 311ab63055c7b0d2e6e2b025bd5190bf 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 28-03-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 CFK41_RS11950 311ab63055c7b0d2e6e2b025bd5190bf 112 PRINTS PR00340 P-II protein signature 2 17 1.5E-29 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CFK41_RS11950 311ab63055c7b0d2e6e2b025bd5190bf 112 PRINTS PR00340 P-II protein signature 52 75 1.5E-29 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CFK41_RS11950 311ab63055c7b0d2e6e2b025bd5190bf 112 PRINTS PR00340 P-II protein signature 83 103 1.5E-29 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CFK41_RS11950 311ab63055c7b0d2e6e2b025bd5190bf 112 PRINTS PR00340 P-II protein signature 23 41 1.5E-29 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CFK41_RS11950 311ab63055c7b0d2e6e2b025bd5190bf 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 4.4E-34 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CFK41_RS11950 311ab63055c7b0d2e6e2b025bd5190bf 112 Gene3D G3DSA:3.30.70.120 1 109 1.5E-40 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CFK41_RS02815 5f624497f1205463f4acbe49a8dd0fe5 553 Pfam PF03070 TENA/THI-4/PQQC family 336 533 1.3E-24 T 28-03-2018 IPR004305 Thiaminase-2/PQQC CFK41_RS02815 5f624497f1205463f4acbe49a8dd0fe5 553 SUPERFAMILY SSF53613 18 278 5.92E-66 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS02815 5f624497f1205463f4acbe49a8dd0fe5 553 Gene3D G3DSA:3.40.1190.20 9 296 1.2E-54 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS02815 5f624497f1205463f4acbe49a8dd0fe5 553 Pfam PF08543 Phosphomethylpyrimidine kinase 28 275 1.4E-73 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CFK41_RS02815 5f624497f1205463f4acbe49a8dd0fe5 553 SUPERFAMILY SSF48613 324 531 4.9E-50 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CFK41_RS02815 5f624497f1205463f4acbe49a8dd0fe5 553 Gene3D G3DSA:1.20.910.10 310 536 3.1E-43 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CFK41_RS02815 5f624497f1205463f4acbe49a8dd0fe5 553 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 21 276 1.7E-70 T 28-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CFK41_RS02290 115962abadeb1faadd03a0b195377a79 178 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 122 3.5E-8 T 28-03-2018 IPR001451 Hexapeptide repeat CFK41_RS02290 115962abadeb1faadd03a0b195377a79 178 SUPERFAMILY SSF51161 9 167 8.73E-46 T 28-03-2018 IPR011004 Trimeric LpxA-like CFK41_RS02290 115962abadeb1faadd03a0b195377a79 178 Gene3D G3DSA:2.160.10.10 2 175 1.1E-40 T 28-03-2018 CFK41_RS16300 9798b01f618394afd7e770e8ac524a76 681 Pfam PF01055 Glycosyl hydrolases family 31 241 668 4.2E-110 T 28-03-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 CFK41_RS16300 9798b01f618394afd7e770e8ac524a76 681 Gene3D G3DSA:2.60.40.1180 607 666 9.8E-19 T 28-03-2018 CFK41_RS16300 9798b01f618394afd7e770e8ac524a76 681 SUPERFAMILY SSF51445 263 602 7.18E-88 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS16300 9798b01f618394afd7e770e8ac524a76 681 SUPERFAMILY SSF74650 2 247 1.82E-57 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CFK41_RS16300 9798b01f618394afd7e770e8ac524a76 681 Pfam PF13802 Galactose mutarotase-like 159 218 2.4E-16 T 28-03-2018 IPR025887 Glycoside hydrolase family 31, N-terminal domain CFK41_RS16300 9798b01f618394afd7e770e8ac524a76 681 Gene3D G3DSA:3.20.20.80 238 606 4.3E-109 T 28-03-2018 CFK41_RS16300 9798b01f618394afd7e770e8ac524a76 681 Gene3D G3DSA:2.60.40.1760 1 237 5.5E-53 T 28-03-2018 CFK41_RS16300 9798b01f618394afd7e770e8ac524a76 681 SUPERFAMILY SSF51011 587 665 7.19E-19 T 28-03-2018 CFK41_RS05170 44847a10a46a02df1eafc7cf2d285860 190 Gene3D G3DSA:3.40.630.30 1 155 6.2E-27 T 28-03-2018 CFK41_RS05170 44847a10a46a02df1eafc7cf2d285860 190 SUPERFAMILY SSF55729 2 149 2.92E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS05170 44847a10a46a02df1eafc7cf2d285860 190 Pfam PF00583 Acetyltransferase (GNAT) family 26 129 1.2E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS02505 0c0724194dec6a52ac2ef327c9b92e1b 599 Gene3D G3DSA:3.40.50.2000 405 579 3.1E-39 T 28-03-2018 CFK41_RS02505 0c0724194dec6a52ac2ef327c9b92e1b 599 Gene3D G3DSA:3.40.50.2000 196 404 2.4E-18 T 28-03-2018 CFK41_RS02505 0c0724194dec6a52ac2ef327c9b92e1b 599 SUPERFAMILY SSF53756 198 598 3.61E-70 T 28-03-2018 CFK41_RS02505 0c0724194dec6a52ac2ef327c9b92e1b 599 Pfam PF00534 Glycosyl transferases group 1 412 576 3.7E-30 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CFK41_RS02505 0c0724194dec6a52ac2ef327c9b92e1b 599 Pfam PF13579 Glycosyl transferase 4-like domain 209 391 1.0E-19 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CFK41_RS03280 c6dcf4c179399ae0c0827b7d3ff0d696 638 SUPERFAMILY SSF63380 316 363 6.28E-7 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CFK41_RS03280 c6dcf4c179399ae0c0827b7d3ff0d696 638 SUPERFAMILY SSF63380 394 464 6.28E-7 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CFK41_RS03280 c6dcf4c179399ae0c0827b7d3ff0d696 638 Pfam PF04954 Siderophore-interacting protein 478 634 1.7E-40 T 28-03-2018 IPR007037 Siderophore-interacting protein CFK41_RS03280 c6dcf4c179399ae0c0827b7d3ff0d696 638 Gene3D G3DSA:3.40.50.300 1 309 2.9E-63 T 28-03-2018 CFK41_RS03280 c6dcf4c179399ae0c0827b7d3ff0d696 638 SMART SM00382 28 217 1.9E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS03280 c6dcf4c179399ae0c0827b7d3ff0d696 638 SUPERFAMILY SSF52540 3 230 3.13E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS03280 c6dcf4c179399ae0c0827b7d3ff0d696 638 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS03280 c6dcf4c179399ae0c0827b7d3ff0d696 638 Gene3D G3DSA:3.40.50.80 472 638 5.1E-50 T 28-03-2018 CFK41_RS03280 c6dcf4c179399ae0c0827b7d3ff0d696 638 Gene3D G3DSA:2.40.30.10 310 462 5.4E-25 T 28-03-2018 CFK41_RS03280 c6dcf4c179399ae0c0827b7d3ff0d696 638 Pfam PF08021 Siderophore-interacting FAD-binding domain 319 461 2.4E-23 T 28-03-2018 IPR013113 FAD-binding 9, siderophore-interacting CFK41_RS03280 c6dcf4c179399ae0c0827b7d3ff0d696 638 Pfam PF00005 ABC transporter 20 167 3.7E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS12055 de8f94ccc32b270f5bab1bf02904a45b 333 Pfam PF00005 ABC transporter 43 186 1.6E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS12055 de8f94ccc32b270f5bab1bf02904a45b 333 SUPERFAMILY SSF52540 37 253 7.61E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS12055 de8f94ccc32b270f5bab1bf02904a45b 333 Gene3D G3DSA:3.40.50.300 10 280 8.2E-55 T 28-03-2018 CFK41_RS12055 de8f94ccc32b270f5bab1bf02904a45b 333 SMART SM00382 51 235 4.6E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS00735 fcf02660005abc4383080560f8034ae0 201 Gene3D G3DSA:3.40.50.850 8 186 6.3E-22 T 28-03-2018 CFK41_RS00735 fcf02660005abc4383080560f8034ae0 201 Pfam PF00857 Isochorismatase family 12 172 4.1E-17 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CFK41_RS00735 fcf02660005abc4383080560f8034ae0 201 SUPERFAMILY SSF52499 11 171 1.18E-20 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CFK41_RS09190 fd3419ba245f6e08e25982c2057699f5 698 Gene3D G3DSA:3.40.50.970 350 566 2.0E-51 T 28-03-2018 CFK41_RS09190 fd3419ba245f6e08e25982c2057699f5 698 Pfam PF02779 Transketolase, pyrimidine binding domain 373 553 9.5E-46 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CFK41_RS09190 fd3419ba245f6e08e25982c2057699f5 698 ProSitePatterns PS00802 Transketolase signature 2. 496 512 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CFK41_RS09190 fd3419ba245f6e08e25982c2057699f5 698 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 15 357 8.8E-126 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CFK41_RS09190 fd3419ba245f6e08e25982c2057699f5 698 TIGRFAM TIGR00232 tktlase_bact: transketolase 17 691 3.5E-234 T 28-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 CFK41_RS09190 fd3419ba245f6e08e25982c2057699f5 698 Gene3D G3DSA:3.40.50.920 568 698 1.7E-31 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CFK41_RS09190 fd3419ba245f6e08e25982c2057699f5 698 SUPERFAMILY SSF52922 563 694 3.27E-39 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CFK41_RS09190 fd3419ba245f6e08e25982c2057699f5 698 Gene3D G3DSA:3.40.50.970 11 344 8.3E-75 T 28-03-2018 CFK41_RS09190 fd3419ba245f6e08e25982c2057699f5 698 SUPERFAMILY SSF52518 10 341 1.26E-91 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CFK41_RS09190 fd3419ba245f6e08e25982c2057699f5 698 Pfam PF02780 Transketolase, C-terminal domain 577 685 5.8E-14 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CFK41_RS09190 fd3419ba245f6e08e25982c2057699f5 698 SUPERFAMILY SSF52518 365 556 6.43E-64 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CFK41_RS09190 fd3419ba245f6e08e25982c2057699f5 698 SMART SM00861 374 554 2.1E-65 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CFK41_RS05355 a4c105c1c18f247137039499627b8710 530 SUPERFAMILY SSF54373 304 468 3.04E-40 T 28-03-2018 CFK41_RS05355 a4c105c1c18f247137039499627b8710 530 Gene3D G3DSA:4.10.450.10 62 114 1.0E-13 T 28-03-2018 CFK41_RS05355 a4c105c1c18f247137039499627b8710 530 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 268 282 - T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CFK41_RS05355 a4c105c1c18f247137039499627b8710 530 SUPERFAMILY SSF51905 14 302 1.84E-72 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS05355 a4c105c1c18f247137039499627b8710 530 SUPERFAMILY SSF51905 467 528 1.84E-72 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS05355 a4c105c1c18f247137039499627b8710 530 PIRSF PIRSF000137 1 330 1.7E-88 T 28-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CFK41_RS05355 a4c105c1c18f247137039499627b8710 530 PIRSF PIRSF000137 335 530 3.9E-46 T 28-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CFK41_RS05355 a4c105c1c18f247137039499627b8710 530 Gene3D G3DSA:3.50.50.60 3 61 0.012 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS05355 a4c105c1c18f247137039499627b8710 530 Gene3D G3DSA:3.30.560.10 115 482 1.4E-93 T 28-03-2018 CFK41_RS05355 a4c105c1c18f247137039499627b8710 530 Pfam PF05199 GMC oxidoreductase 381 520 6.4E-38 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CFK41_RS05355 a4c105c1c18f247137039499627b8710 530 Pfam PF00732 GMC oxidoreductase 15 310 3.1E-73 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CFK41_RS01115 289b5aa8f0385ae7017b843fcc336efc 169 SUPERFAMILY SSF55961 15 163 8.06E-14 T 28-03-2018 CFK41_RS01115 289b5aa8f0385ae7017b843fcc336efc 169 Gene3D G3DSA:3.30.530.20 9 169 2.0E-18 T 28-03-2018 IPR023393 START-like domain CFK41_RS06440 0676f9e61396375828ea82aefb2d312d 434 Pfam PF07730 Histidine kinase 209 275 1.9E-18 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CFK41_RS06440 0676f9e61396375828ea82aefb2d312d 434 Gene3D G3DSA:3.30.565.10 236 408 3.8E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS06440 0676f9e61396375828ea82aefb2d312d 434 SUPERFAMILY SSF55874 289 407 8.46E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS06440 0676f9e61396375828ea82aefb2d312d 434 SMART SM00387 316 409 1.0E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS00185 56db84089f9455e34954a46b0e4dccf9 252 Gene3D G3DSA:1.10.10.10 1 75 5.4E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS00185 56db84089f9455e34954a46b0e4dccf9 252 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CFK41_RS00185 56db84089f9455e34954a46b0e4dccf9 252 Gene3D G3DSA:3.40.50.1360 76 235 4.7E-25 T 28-03-2018 CFK41_RS00185 56db84089f9455e34954a46b0e4dccf9 252 SUPERFAMILY SSF46785 6 60 1.37E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS00185 56db84089f9455e34954a46b0e4dccf9 252 Pfam PF00455 DeoR C terminal sensor domain 76 230 4.2E-33 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CFK41_RS00185 56db84089f9455e34954a46b0e4dccf9 252 SMART SM01134 73 233 3.3E-42 T 28-03-2018 CFK41_RS00185 56db84089f9455e34954a46b0e4dccf9 252 SMART SM00420 6 58 6.2E-13 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CFK41_RS00185 56db84089f9455e34954a46b0e4dccf9 252 SUPERFAMILY SSF100950 78 233 1.99E-20 T 28-03-2018 CFK41_RS00185 56db84089f9455e34954a46b0e4dccf9 252 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 7.2E-13 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CFK41_RS02715 1276de63a6da298885306f48f6f268a6 388 Gene3D G3DSA:1.10.10.10 34 98 1.8E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS02715 1276de63a6da298885306f48f6f268a6 388 SUPERFAMILY SSF46785 36 101 3.26E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS02715 1276de63a6da298885306f48f6f268a6 388 Gene3D G3DSA:3.30.420.40 227 382 9.0E-32 T 28-03-2018 CFK41_RS02715 1276de63a6da298885306f48f6f268a6 388 Pfam PF00480 ROK family 281 377 3.9E-8 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CFK41_RS02715 1276de63a6da298885306f48f6f268a6 388 Pfam PF00480 ROK family 117 266 2.4E-18 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CFK41_RS02715 1276de63a6da298885306f48f6f268a6 388 Gene3D G3DSA:3.30.420.40 99 226 6.9E-21 T 28-03-2018 CFK41_RS02715 1276de63a6da298885306f48f6f268a6 388 Pfam PF01047 MarR family 43 84 1.2E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS02715 1276de63a6da298885306f48f6f268a6 388 SUPERFAMILY SSF53067 107 381 3.67E-32 T 28-03-2018 CFK41_RS15165 038fe5654c994589c6a5266a8f1ee2c9 464 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 12 312 3.8E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS15165 038fe5654c994589c6a5266a8f1ee2c9 464 SUPERFAMILY SSF55424 341 457 5.33E-28 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CFK41_RS15165 038fe5654c994589c6a5266a8f1ee2c9 464 Gene3D G3DSA:3.40.50.720 159 344 5.6E-37 T 28-03-2018 CFK41_RS15165 038fe5654c994589c6a5266a8f1ee2c9 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 191 5.9E-28 T 28-03-2018 CFK41_RS15165 038fe5654c994589c6a5266a8f1ee2c9 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 276 5.9E-28 T 28-03-2018 CFK41_RS15165 038fe5654c994589c6a5266a8f1ee2c9 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 289 311 5.9E-28 T 28-03-2018 CFK41_RS15165 038fe5654c994589c6a5266a8f1ee2c9 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 134 152 5.9E-28 T 28-03-2018 CFK41_RS15165 038fe5654c994589c6a5266a8f1ee2c9 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 5.9E-28 T 28-03-2018 CFK41_RS15165 038fe5654c994589c6a5266a8f1ee2c9 464 Gene3D G3DSA:3.50.50.60 10 158 6.7E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS15165 038fe5654c994589c6a5266a8f1ee2c9 464 SUPERFAMILY SSF51905 10 314 1.47E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS15165 038fe5654c994589c6a5266a8f1ee2c9 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 261 275 1.4E-51 T 28-03-2018 CFK41_RS15165 038fe5654c994589c6a5266a8f1ee2c9 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 46 61 1.4E-51 T 28-03-2018 CFK41_RS15165 038fe5654c994589c6a5266a8f1ee2c9 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 173 198 1.4E-51 T 28-03-2018 CFK41_RS15165 038fe5654c994589c6a5266a8f1ee2c9 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 137 146 1.4E-51 T 28-03-2018 CFK41_RS15165 038fe5654c994589c6a5266a8f1ee2c9 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 304 311 1.4E-51 T 28-03-2018 CFK41_RS15165 038fe5654c994589c6a5266a8f1ee2c9 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 341 362 1.4E-51 T 28-03-2018 CFK41_RS15165 038fe5654c994589c6a5266a8f1ee2c9 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 12 34 1.4E-51 T 28-03-2018 CFK41_RS15165 038fe5654c994589c6a5266a8f1ee2c9 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 409 424 1.4E-51 T 28-03-2018 CFK41_RS15165 038fe5654c994589c6a5266a8f1ee2c9 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 431 451 1.4E-51 T 28-03-2018 CFK41_RS15165 038fe5654c994589c6a5266a8f1ee2c9 464 PIRSF PIRSF000350 1 454 1.2E-81 T 28-03-2018 CFK41_RS15165 038fe5654c994589c6a5266a8f1ee2c9 464 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 345 455 1.2E-21 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CFK41_RS15165 038fe5654c994589c6a5266a8f1ee2c9 464 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 47 57 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CFK41_RS15165 038fe5654c994589c6a5266a8f1ee2c9 464 Gene3D G3DSA:3.30.390.30 345 462 1.7E-30 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CFK41_RS03715 7ad9a7be9af3228999a31f7fab1603bf 508 Gene3D G3DSA:3.30.559.10 261 507 1.5E-79 T 28-03-2018 CFK41_RS03715 7ad9a7be9af3228999a31f7fab1603bf 508 Pfam PF00364 Biotin-requiring enzyme 16 87 2.9E-12 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CFK41_RS03715 7ad9a7be9af3228999a31f7fab1603bf 508 Pfam PF02817 e3 binding domain 194 229 1.1E-10 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CFK41_RS03715 7ad9a7be9af3228999a31f7fab1603bf 508 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 277 503 8.9E-77 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CFK41_RS03715 7ad9a7be9af3228999a31f7fab1603bf 508 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 38 67 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CFK41_RS03715 7ad9a7be9af3228999a31f7fab1603bf 508 Gene3D G3DSA:4.10.320.10 193 235 1.7E-13 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CFK41_RS03715 7ad9a7be9af3228999a31f7fab1603bf 508 SUPERFAMILY SSF47005 193 232 3.53E-9 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CFK41_RS03715 7ad9a7be9af3228999a31f7fab1603bf 508 SUPERFAMILY SSF51230 14 107 4.19E-18 T 28-03-2018 IPR011053 Single hybrid motif CFK41_RS03715 7ad9a7be9af3228999a31f7fab1603bf 508 Gene3D G3DSA:3.90.1170.30 2 59 4.7E-8 T 28-03-2018 CFK41_RS03715 7ad9a7be9af3228999a31f7fab1603bf 508 Gene3D G3DSA:2.40.50.100 60 192 1.5E-5 T 28-03-2018 CFK41_RS03715 7ad9a7be9af3228999a31f7fab1603bf 508 SUPERFAMILY SSF52777 270 505 1.51E-76 T 28-03-2018 CFK41_RS09600 dd9243f84a2cc611840c4677d154f741 245 SUPERFAMILY SSF46785 13 220 2.94E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS09600 dd9243f84a2cc611840c4677d154f741 245 Gene3D G3DSA:1.10.10.10 10 79 2.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS09600 dd9243f84a2cc611840c4677d154f741 245 Pfam PF13412 Winged helix-turn-helix DNA-binding 26 57 2.2E-6 T 28-03-2018 CFK41_RS16550 c17d741afc89e207dceb7f2bfe45592d 321 Gene3D G3DSA:3.40.1190.20 4 320 2.8E-60 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS16550 c17d741afc89e207dceb7f2bfe45592d 321 Pfam PF00294 pfkB family carbohydrate kinase 6 298 4.5E-50 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CFK41_RS16550 c17d741afc89e207dceb7f2bfe45592d 321 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 255 268 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CFK41_RS16550 c17d741afc89e207dceb7f2bfe45592d 321 SUPERFAMILY SSF53613 6 311 3.9E-72 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS15595 2970ae4b741de4b9a3d0334778155599 262 Pfam PF00005 ABC transporter 29 165 4.9E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS15595 2970ae4b741de4b9a3d0334778155599 262 SUPERFAMILY SSF52540 12 233 1.1E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS15595 2970ae4b741de4b9a3d0334778155599 262 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS15595 2970ae4b741de4b9a3d0334778155599 262 Gene3D G3DSA:3.40.50.300 5 225 1.2E-59 T 28-03-2018 CFK41_RS15595 2970ae4b741de4b9a3d0334778155599 262 SMART SM00382 38 216 3.5E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS07300 0b86ccedf613738dd50613ac470c7f6c 361 SUPERFAMILY SSF51679 9 342 1.7E-72 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CFK41_RS07300 0b86ccedf613738dd50613ac470c7f6c 361 TIGRFAM TIGR03858 LLM_2I7G: probable oxidoreductase, LLM family 10 341 2.9E-143 T 28-03-2018 IPR022290 Conserved hypothetical protein CHP03858, luciferase-like monooxygenase, putative CFK41_RS07300 0b86ccedf613738dd50613ac470c7f6c 361 Gene3D G3DSA:3.20.20.30 2 347 9.6E-73 T 28-03-2018 CFK41_RS07300 0b86ccedf613738dd50613ac470c7f6c 361 Pfam PF00296 Luciferase-like monooxygenase 26 307 1.0E-45 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CFK41_RS14175 62f5b87987f72d361d2a9e8639f5566e 653 Gene3D G3DSA:3.40.190.10 247 379 5.5E-20 T 28-03-2018 CFK41_RS14175 62f5b87987f72d361d2a9e8639f5566e 653 Gene3D G3DSA:3.40.190.10 380 602 2.8E-31 T 28-03-2018 CFK41_RS14175 62f5b87987f72d361d2a9e8639f5566e 653 Pfam PF13416 Bacterial extracellular solute-binding protein 270 579 2.8E-27 T 28-03-2018 CFK41_RS14175 62f5b87987f72d361d2a9e8639f5566e 653 SUPERFAMILY SSF53850 231 643 7.76E-57 T 28-03-2018 CFK41_RS08130 99b7cb943b031f8ca50b0b6d75f4ec22 282 Pfam PF09685 Domain of unknown function (DUF4870) 165 281 4.9E-26 T 28-03-2018 IPR019109 Protein of unknown function DUF4870 CFK41_RS00805 48e049fbde35c3a8a9ab00b3402b9fc6 534 Pfam PF14067 LssY C-terminus 97 288 1.1E-67 T 28-03-2018 IPR025902 LssY-like C-terminal domain CFK41_RS01575 0be5396432d9dd4b686640a0ffe260fc 544 Gene3D G3DSA:3.30.420.40 277 536 7.1E-33 T 28-03-2018 CFK41_RS01575 0be5396432d9dd4b686640a0ffe260fc 544 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 25 248 2.8E-13 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CFK41_RS01575 0be5396432d9dd4b686640a0ffe260fc 544 Gene3D G3DSA:3.30.420.40 18 276 2.0E-37 T 28-03-2018 CFK41_RS01575 0be5396432d9dd4b686640a0ffe260fc 544 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 285 483 9.6E-34 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CFK41_RS01575 0be5396432d9dd4b686640a0ffe260fc 544 SUPERFAMILY SSF53067 24 246 7.22E-26 T 28-03-2018 CFK41_RS01575 0be5396432d9dd4b686640a0ffe260fc 544 SUPERFAMILY SSF53067 280 532 9.36E-17 T 28-03-2018 CFK41_RS12765 3839adf0b1776b25ccebcc792a3c6e11 543 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 103 462 2.4E-68 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CFK41_RS12765 3839adf0b1776b25ccebcc792a3c6e11 543 Gene3D G3DSA:3.90.76.10 76 179 9.5E-28 T 28-03-2018 CFK41_RS12765 3839adf0b1776b25ccebcc792a3c6e11 543 Gene3D G3DSA:3.10.105.10 312 510 7.6E-29 T 28-03-2018 CFK41_RS12765 3839adf0b1776b25ccebcc792a3c6e11 543 PIRSF PIRSF002741 19 528 1.0E-62 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CFK41_RS12765 3839adf0b1776b25ccebcc792a3c6e11 543 Gene3D G3DSA:3.40.190.10 180 311 1.6E-31 T 28-03-2018 CFK41_RS12765 3839adf0b1776b25ccebcc792a3c6e11 543 SUPERFAMILY SSF53850 56 537 7.6E-95 T 28-03-2018 CFK41_RS14700 f5dc686122b38a526ffa971344a0fac8 355 SUPERFAMILY SSF55031 171 252 1.57E-15 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CFK41_RS14700 f5dc686122b38a526ffa971344a0fac8 355 Pfam PF07687 Peptidase dimerisation domain 168 251 1.6E-14 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CFK41_RS14700 f5dc686122b38a526ffa971344a0fac8 355 Gene3D G3DSA:3.40.630.10 3 173 1.8E-21 T 28-03-2018 CFK41_RS14700 f5dc686122b38a526ffa971344a0fac8 355 Gene3D G3DSA:3.30.70.360 174 281 5.2E-18 T 28-03-2018 CFK41_RS14700 f5dc686122b38a526ffa971344a0fac8 355 SUPERFAMILY SSF53187 4 170 3.83E-43 T 28-03-2018 CFK41_RS14700 f5dc686122b38a526ffa971344a0fac8 355 SUPERFAMILY SSF53187 278 352 3.83E-43 T 28-03-2018 CFK41_RS14700 f5dc686122b38a526ffa971344a0fac8 355 Pfam PF01546 Peptidase family M20/M25/M40 66 352 3.2E-21 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CFK41_RS04875 5583b0d870196d543978097e5398ae60 312 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 26 266 3.3E-50 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CFK41_RS04875 5583b0d870196d543978097e5398ae60 312 Pfam PF01416 tRNA pseudouridine synthase 175 289 1.4E-21 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CFK41_RS04875 5583b0d870196d543978097e5398ae60 312 Pfam PF01416 tRNA pseudouridine synthase 30 135 6.4E-6 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CFK41_RS04875 5583b0d870196d543978097e5398ae60 312 SUPERFAMILY SSF55120 22 294 2.73E-71 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CFK41_RS04875 5583b0d870196d543978097e5398ae60 312 PIRSF PIRSF001430 22 305 1.8E-72 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CFK41_RS04875 5583b0d870196d543978097e5398ae60 312 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 23 288 32.691 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CFK41_RS04875 5583b0d870196d543978097e5398ae60 312 Gene3D G3DSA:3.30.70.580 20 137 1.4E-33 T 28-03-2018 CFK41_RS04875 5583b0d870196d543978097e5398ae60 312 Gene3D G3DSA:3.30.70.660 138 287 3.4E-31 T 28-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CFK41_RS17005 9630464a5485961d756f249036fbd83f 112 Gene3D G3DSA:3.40.1620.10 41 73 0.0011 T 28-03-2018 CFK41_RS17005 9630464a5485961d756f249036fbd83f 112 SUPERFAMILY SSF54909 1 102 1.5E-23 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CFK41_RS17005 9630464a5485961d756f249036fbd83f 112 Pfam PF05336 L-rhamnose mutarotase 4 91 8.7E-17 T 28-03-2018 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 CFK41_RS13655 9b4bce23813bd4fcb152039e585a8e7a 600 SUPERFAMILY SSF53474 321 455 9.49E-7 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS13655 9b4bce23813bd4fcb152039e585a8e7a 600 Pfam PF10081 Alpha/beta-hydrolase family 291 573 2.4E-108 T 28-03-2018 IPR027787 Alpha/beta-hydrolase, catalytic domain CFK41_RS13655 9b4bce23813bd4fcb152039e585a8e7a 600 Gene3D G3DSA:3.40.50.1820 320 586 7.3E-6 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS13655 9b4bce23813bd4fcb152039e585a8e7a 600 Pfam PF15420 Alpha/beta-hydrolase family N-terminus 63 273 1.9E-46 T 28-03-2018 IPR027788 Alpha/beta-hydrolase, N-terminal domain CFK41_RS10680 df1928003050fc46766dbe1a54b321c8 140 SUPERFAMILY SSF55174 13 95 3.01E-21 T 28-03-2018 CFK41_RS10680 df1928003050fc46766dbe1a54b321c8 140 PIRSF PIRSF016821 10 131 3.8E-38 T 28-03-2018 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 CFK41_RS10680 df1928003050fc46766dbe1a54b321c8 140 Gene3D G3DSA:3.10.290.10 9 109 3.8E-20 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CFK41_RS10680 df1928003050fc46766dbe1a54b321c8 140 SMART SM00363 13 70 5.2E-9 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CFK41_RS10680 df1928003050fc46766dbe1a54b321c8 140 Pfam PF01479 S4 domain 13 58 8.2E-11 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CFK41_RS16465 d9bdd7517df6f5f280003ff09b447316 270 SUPERFAMILY SSF161098 3 270 8.6E-57 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS16465 d9bdd7517df6f5f280003ff09b447316 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 265 3.5E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS16465 d9bdd7517df6f5f280003ff09b447316 270 Gene3D G3DSA:1.10.3720.10 1 258 2.9E-35 T 28-03-2018 CFK41_RS09090 c91a49148a006f78ed6590442160e86d 402 Gene3D G3DSA:3.40.350.10 1 148 1.3E-22 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CFK41_RS09090 c91a49148a006f78ed6590442160e86d 402 SUPERFAMILY SSF53092 5 150 1.92E-31 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CFK41_RS09090 c91a49148a006f78ed6590442160e86d 402 Pfam PF01321 Creatinase/Prolidase N-terminal domain 17 151 4.9E-19 T 28-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CFK41_RS09090 c91a49148a006f78ed6590442160e86d 402 Gene3D G3DSA:3.90.230.10 151 384 7.7E-40 T 28-03-2018 CFK41_RS09090 c91a49148a006f78ed6590442160e86d 402 Pfam PF00557 Metallopeptidase family M24 164 369 2.0E-29 T 28-03-2018 IPR000994 Peptidase M24 CFK41_RS09090 c91a49148a006f78ed6590442160e86d 402 SUPERFAMILY SSF55920 153 382 1.83E-47 T 28-03-2018 IPR000994 Peptidase M24 CFK41_RS09420 509e8dc07d098d29c3355c669324e3cc 352 PIRSF PIRSF006493 282 351 3400.0 T 28-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CFK41_RS09420 509e8dc07d098d29c3355c669324e3cc 352 PIRSF PIRSF006493 1 300 5.5E-76 T 28-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CFK41_RS09420 509e8dc07d098d29c3355c669324e3cc 352 SMART SM00559 52 179 1.3E-31 T 28-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 CFK41_RS09420 509e8dc07d098d29c3355c669324e3cc 352 Pfam PF02735 Ku70/Ku80 beta-barrel domain 11 176 1.0E-33 T 28-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 CFK41_RS09420 509e8dc07d098d29c3355c669324e3cc 352 Gene3D G3DSA:2.40.290.10 1 179 2.2E-30 T 28-03-2018 IPR016194 SPOC-like, C-terminal domain CFK41_RS09420 509e8dc07d098d29c3355c669324e3cc 352 SUPERFAMILY SSF100939 1 259 2.94E-52 T 28-03-2018 IPR016194 SPOC-like, C-terminal domain CFK41_RS09420 509e8dc07d098d29c3355c669324e3cc 352 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 258 29.869 T 28-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CFK41_RS09420 509e8dc07d098d29c3355c669324e3cc 352 TIGRFAM TIGR02772 Ku_bact: Ku protein 1 260 3.8E-77 T 28-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CFK41_RS00210 bb0a305cbb184d1bb7dd04bc4599ddfb 196 SUPERFAMILY SSF88659 133 193 5.61E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS00210 bb0a305cbb184d1bb7dd04bc4599ddfb 196 Pfam PF08281 Sigma-70, region 4 136 188 8.0E-12 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS00210 bb0a305cbb184d1bb7dd04bc4599ddfb 196 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 23 191 2.0E-23 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS00210 bb0a305cbb184d1bb7dd04bc4599ddfb 196 Gene3D G3DSA:1.10.10.10 98 195 8.8E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS00210 bb0a305cbb184d1bb7dd04bc4599ddfb 196 Gene3D G3DSA:1.10.1740.10 3 97 1.7E-23 T 28-03-2018 CFK41_RS00210 bb0a305cbb184d1bb7dd04bc4599ddfb 196 SUPERFAMILY SSF88946 5 108 2.35E-26 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS00210 bb0a305cbb184d1bb7dd04bc4599ddfb 196 Pfam PF04542 Sigma-70 region 2 27 95 3.6E-13 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS07230 055a74e340fccca994291a905b9b4a6a 610 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CFK41_RS07230 055a74e340fccca994291a905b9b4a6a 610 Gene3D G3DSA:3.40.50.2300 90 179 5.6E-4 T 28-03-2018 CFK41_RS07230 055a74e340fccca994291a905b9b4a6a 610 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 606 6.0E-233 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CFK41_RS07230 055a74e340fccca994291a905b9b4a6a 610 Pfam PF00920 Dehydratase family 34 604 1.3E-209 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CFK41_RS07230 055a74e340fccca994291a905b9b4a6a 610 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 607 43.758 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CFK41_RS07230 055a74e340fccca994291a905b9b4a6a 610 SUPERFAMILY SSF52016 421 607 2.51E-58 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CFK41_RS07230 055a74e340fccca994291a905b9b4a6a 610 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 509 520 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CFK41_RS07230 055a74e340fccca994291a905b9b4a6a 610 SUPERFAMILY SSF143975 3 420 1.57E-130 T 28-03-2018 CFK41_RS09965 39f51492fccbe8a8bd5eee9b289b847f 202 SUPERFAMILY SSF50249 2 62 9.14E-13 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS09965 39f51492fccbe8a8bd5eee9b289b847f 202 Pfam PF01330 RuvA N terminal domain 2 61 2.0E-17 T 28-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 CFK41_RS09965 39f51492fccbe8a8bd5eee9b289b847f 202 SUPERFAMILY SSF47781 65 132 1.37E-18 T 28-03-2018 IPR010994 RuvA domain 2-like CFK41_RS09965 39f51492fccbe8a8bd5eee9b289b847f 202 Pfam PF07499 RuvA, C-terminal domain 154 198 3.5E-9 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CFK41_RS09965 39f51492fccbe8a8bd5eee9b289b847f 202 SMART SM00278 107 126 9.2 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CFK41_RS09965 39f51492fccbe8a8bd5eee9b289b847f 202 SMART SM00278 72 91 8.7 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CFK41_RS09965 39f51492fccbe8a8bd5eee9b289b847f 202 Pfam PF14520 Helix-hairpin-helix domain 71 127 2.2E-14 T 28-03-2018 CFK41_RS09965 39f51492fccbe8a8bd5eee9b289b847f 202 Gene3D G3DSA:1.10.150.20 65 81 0.25 T 28-03-2018 CFK41_RS09965 39f51492fccbe8a8bd5eee9b289b847f 202 Gene3D G3DSA:1.10.8.50 114 165 5.3E-5 T 28-03-2018 CFK41_RS09965 39f51492fccbe8a8bd5eee9b289b847f 202 SUPERFAMILY SSF46929 154 200 2.35E-7 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CFK41_RS09965 39f51492fccbe8a8bd5eee9b289b847f 202 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 199 26.852 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CFK41_RS09965 39f51492fccbe8a8bd5eee9b289b847f 202 Gene3D G3DSA:1.10.150.20 82 113 7.6E-5 T 28-03-2018 CFK41_RS09965 39f51492fccbe8a8bd5eee9b289b847f 202 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 195 7.3E-35 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CFK41_RS09965 39f51492fccbe8a8bd5eee9b289b847f 202 Gene3D G3DSA:1.10.8.10 166 202 8.9E-11 T 28-03-2018 CFK41_RS09965 39f51492fccbe8a8bd5eee9b289b847f 202 Gene3D G3DSA:2.40.50.140 1 62 8.3E-22 T 28-03-2018 CFK41_RS10540 6bef772313eee6bed1001268b853a748 361 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS10540 6bef772313eee6bed1001268b853a748 361 Pfam PF03459 TOBE domain 292 350 1.9E-7 T 28-03-2018 IPR005116 Transport-associated OB, type 1 CFK41_RS10540 6bef772313eee6bed1001268b853a748 361 Pfam PF00005 ABC transporter 22 163 4.3E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS10540 6bef772313eee6bed1001268b853a748 361 SUPERFAMILY SSF52540 4 244 2.66E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS10540 6bef772313eee6bed1001268b853a748 361 Gene3D G3DSA:2.40.50.100 246 283 8.2E-14 T 28-03-2018 CFK41_RS10540 6bef772313eee6bed1001268b853a748 361 Gene3D G3DSA:3.40.50.300 1 245 1.2E-68 T 28-03-2018 CFK41_RS10540 6bef772313eee6bed1001268b853a748 361 SMART SM00382 30 213 2.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS10540 6bef772313eee6bed1001268b853a748 361 Gene3D G3DSA:2.40.50.140 285 340 3.5E-16 T 28-03-2018 CFK41_RS10540 6bef772313eee6bed1001268b853a748 361 SUPERFAMILY SSF50331 238 359 1.43E-26 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CFK41_RS01320 1cacda9e5610d202d23626bc0d871bd9 366 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 150 359 5.2E-36 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01320 1cacda9e5610d202d23626bc0d871bd9 366 Gene3D G3DSA:1.10.3720.10 28 348 6.9E-32 T 28-03-2018 CFK41_RS01320 1cacda9e5610d202d23626bc0d871bd9 366 SUPERFAMILY SSF161098 223 342 1.46E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01320 1cacda9e5610d202d23626bc0d871bd9 366 SUPERFAMILY SSF161098 128 196 1.46E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01055 3c994c325bc7523dcb0e4cfbbcb73a06 323 SUPERFAMILY SSF53850 14 29 1.05E-46 T 28-03-2018 CFK41_RS01055 3c994c325bc7523dcb0e4cfbbcb73a06 323 SUPERFAMILY SSF53850 70 300 1.05E-46 T 28-03-2018 CFK41_RS01055 3c994c325bc7523dcb0e4cfbbcb73a06 323 Gene3D G3DSA:3.40.190.10 71 187 4.6E-19 T 28-03-2018 CFK41_RS01055 3c994c325bc7523dcb0e4cfbbcb73a06 323 Gene3D G3DSA:3.40.190.10 188 269 1.0E-16 T 28-03-2018 CFK41_RS01055 3c994c325bc7523dcb0e4cfbbcb73a06 323 SMART SM00062 81 307 4.5E-40 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CFK41_RS01055 3c994c325bc7523dcb0e4cfbbcb73a06 323 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 99 299 4.4E-39 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CFK41_RS16455 7fd5580da0b8a2b496328e5a59bbd2b7 441 Gene3D G3DSA:3.40.190.10 42 216 2.9E-34 T 28-03-2018 CFK41_RS16455 7fd5580da0b8a2b496328e5a59bbd2b7 441 Pfam PF01547 Bacterial extracellular solute-binding protein 58 349 6.2E-26 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CFK41_RS16455 7fd5580da0b8a2b496328e5a59bbd2b7 441 SUPERFAMILY SSF53850 24 435 6.33E-57 T 28-03-2018 CFK41_RS00365 fa4dbc18116fb9fe0b37dac6410049d0 119 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 113 1.8E-7 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CFK41_RS00365 fa4dbc18116fb9fe0b37dac6410049d0 119 Gene3D G3DSA:3.10.180.10 3 118 1.8E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS00365 fa4dbc18116fb9fe0b37dac6410049d0 119 SUPERFAMILY SSF54593 6 118 8.19E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS15220 d0e3b597134c674cebf312da5bbb0f3e 436 SUPERFAMILY SSF53850 21 434 7.41E-64 T 28-03-2018 CFK41_RS15220 d0e3b597134c674cebf312da5bbb0f3e 436 Gene3D G3DSA:3.40.190.10 227 377 6.0E-10 T 28-03-2018 CFK41_RS15220 d0e3b597134c674cebf312da5bbb0f3e 436 Pfam PF01547 Bacterial extracellular solute-binding protein 59 348 1.9E-44 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CFK41_RS15220 d0e3b597134c674cebf312da5bbb0f3e 436 Gene3D G3DSA:3.40.190.10 23 203 7.5E-34 T 28-03-2018 CFK41_RS11660 4a7958bec954a7ed6b4cff75d50e6304 972 Pfam PF09397 Ftsk gamma domain 830 886 5.4E-21 T 28-03-2018 IPR018541 FtsK gamma domain CFK41_RS11660 4a7958bec954a7ed6b4cff75d50e6304 972 Pfam PF01580 FtsK/SpoIIIE family 527 726 1.0E-56 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CFK41_RS11660 4a7958bec954a7ed6b4cff75d50e6304 972 SUPERFAMILY SSF46785 826 890 2.99E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS11660 4a7958bec954a7ed6b4cff75d50e6304 972 SMART SM00843 825 889 2.7E-28 T 28-03-2018 IPR018541 FtsK gamma domain CFK41_RS11660 4a7958bec954a7ed6b4cff75d50e6304 972 SUPERFAMILY SSF52540 500 799 7.82E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11660 4a7958bec954a7ed6b4cff75d50e6304 972 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 112 219 9.8E-9 T 28-03-2018 IPR025199 DNA translocase FtsK, 4TM region CFK41_RS11660 4a7958bec954a7ed6b4cff75d50e6304 972 Gene3D G3DSA:1.10.10.10 826 880 3.2E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS11660 4a7958bec954a7ed6b4cff75d50e6304 972 Gene3D G3DSA:3.40.50.300 271 819 4.1E-47 T 28-03-2018 CFK41_RS15100 e71385a96428b293ab1c838405267786 390 SUPERFAMILY SSF55347 130 290 1.26E-24 T 28-03-2018 CFK41_RS15100 e71385a96428b293ab1c838405267786 390 Gene3D G3DSA:3.40.50.720 1 142 9.9E-36 T 28-03-2018 CFK41_RS15100 e71385a96428b293ab1c838405267786 390 Gene3D G3DSA:3.30.360.10 143 381 7.2E-40 T 28-03-2018 CFK41_RS15100 e71385a96428b293ab1c838405267786 390 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 136 218 2.5E-9 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CFK41_RS15100 e71385a96428b293ab1c838405267786 390 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 124 2.2E-20 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS15100 e71385a96428b293ab1c838405267786 390 SUPERFAMILY SSF51735 3 153 4.96E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS12895 c710e6dbf15df6338d4849bb23687331 251 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 20 249 7.8E-47 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CFK41_RS12895 c710e6dbf15df6338d4849bb23687331 251 Pfam PF01168 Alanine racemase, N-terminal domain 26 250 1.4E-21 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CFK41_RS12895 c710e6dbf15df6338d4849bb23687331 251 PIRSF PIRSF004848 10 251 1.9E-61 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CFK41_RS12895 c710e6dbf15df6338d4849bb23687331 251 Gene3D G3DSA:3.20.20.10 4 251 2.1E-56 T 28-03-2018 IPR029066 PLP-binding barrel CFK41_RS12895 c710e6dbf15df6338d4849bb23687331 251 SUPERFAMILY SSF51419 17 247 6.87E-57 T 28-03-2018 IPR029066 PLP-binding barrel CFK41_RS09035 760b060ef930fd2db9a5701bdf1ecec8 352 Pfam PF03358 NADPH-dependent FMN reductase 6 152 1.1E-31 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CFK41_RS09035 760b060ef930fd2db9a5701bdf1ecec8 352 Gene3D G3DSA:3.40.50.360 1 199 6.2E-33 T 28-03-2018 IPR029039 Flavoprotein-like domain CFK41_RS09035 760b060ef930fd2db9a5701bdf1ecec8 352 Pfam PF00583 Acetyltransferase (GNAT) family 241 335 1.5E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS09035 760b060ef930fd2db9a5701bdf1ecec8 352 SUPERFAMILY SSF52218 6 179 6.83E-32 T 28-03-2018 IPR029039 Flavoprotein-like domain CFK41_RS09035 760b060ef930fd2db9a5701bdf1ecec8 352 Gene3D G3DSA:3.40.630.30 205 345 2.3E-22 T 28-03-2018 CFK41_RS09035 760b060ef930fd2db9a5701bdf1ecec8 352 SUPERFAMILY SSF55729 207 340 2.84E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS00105 c146d097acdd82c0dfb0e647f9da5fef 222 SUPERFAMILY SSF56784 10 215 2.38E-33 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS00105 c146d097acdd82c0dfb0e647f9da5fef 222 Gene3D G3DSA:3.40.50.1000 70 221 2.9E-25 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS00105 c146d097acdd82c0dfb0e647f9da5fef 222 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 103 183 4.0E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CFK41_RS00105 c146d097acdd82c0dfb0e647f9da5fef 222 Pfam PF13419 Haloacid dehalogenase-like hydrolase 11 189 2.5E-21 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS17315 0be84dc2843d1ddb5cfeee569594d591 130 ProSitePatterns PS00552 MerR-type HTH domain signature. 19 41 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS17315 0be84dc2843d1ddb5cfeee569594d591 130 Gene3D G3DSA:1.10.1660.10 70 130 8.4E-9 T 28-03-2018 CFK41_RS17315 0be84dc2843d1ddb5cfeee569594d591 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 17 28 2.2E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS17315 0be84dc2843d1ddb5cfeee569594d591 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 28 41 2.2E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS17315 0be84dc2843d1ddb5cfeee569594d591 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 51 71 2.2E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS17315 0be84dc2843d1ddb5cfeee569594d591 130 Gene3D G3DSA:1.10.1660.10 28 69 4.8E-22 T 28-03-2018 CFK41_RS17315 0be84dc2843d1ddb5cfeee569594d591 130 SMART SM00422 16 84 1.1E-21 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS17315 0be84dc2843d1ddb5cfeee569594d591 130 SUPERFAMILY SSF46955 16 124 8.79E-28 T 28-03-2018 IPR009061 Putative DNA-binding domain CFK41_RS17315 0be84dc2843d1ddb5cfeee569594d591 130 Pfam PF13411 MerR HTH family regulatory protein 17 82 4.6E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS17315 0be84dc2843d1ddb5cfeee569594d591 130 Gene3D G3DSA:1.10.10.10 6 27 0.0019 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS09685 3fd27097eea61f4aae3738643ede11b5 179 Gene3D G3DSA:2.70.40.10 5 126 1.8E-38 T 28-03-2018 CFK41_RS09685 3fd27097eea61f4aae3738643ede11b5 179 TIGRFAM TIGR00576 dut: dUTP diphosphatase 28 162 1.1E-47 T 28-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 CFK41_RS09685 3fd27097eea61f4aae3738643ede11b5 179 Gene3D G3DSA:2.70.40.10 127 162 1.4E-11 T 28-03-2018 CFK41_RS09685 3fd27097eea61f4aae3738643ede11b5 179 Pfam PF00692 dUTPase 33 162 4.8E-34 T 28-03-2018 IPR029054 dUTPase-like CFK41_RS09685 3fd27097eea61f4aae3738643ede11b5 179 SUPERFAMILY SSF51283 23 162 4.45E-45 T 28-03-2018 IPR029054 dUTPase-like CFK41_RS12785 1dcc055c646e030a806ccf029dcf77c0 318 SUPERFAMILY SSF51569 2 308 4.29E-70 T 28-03-2018 CFK41_RS12785 1dcc055c646e030a806ccf029dcf77c0 318 PRINTS PR00146 Dihydrodipicolinate synthase signature 109 125 4.8E-6 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS12785 1dcc055c646e030a806ccf029dcf77c0 318 PRINTS PR00146 Dihydrodipicolinate synthase signature 134 151 4.8E-6 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS12785 1dcc055c646e030a806ccf029dcf77c0 318 PRINTS PR00146 Dihydrodipicolinate synthase signature 41 62 4.8E-6 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS12785 1dcc055c646e030a806ccf029dcf77c0 318 PRINTS PR00146 Dihydrodipicolinate synthase signature 77 95 4.8E-6 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS12785 1dcc055c646e030a806ccf029dcf77c0 318 Gene3D G3DSA:3.20.20.70 1 317 6.7E-75 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS12785 1dcc055c646e030a806ccf029dcf77c0 318 Pfam PF00701 Dihydrodipicolinate synthetase family 8 302 1.3E-43 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS12785 1dcc055c646e030a806ccf029dcf77c0 318 PIRSF PIRSF001365 3 317 2.7E-71 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS12785 1dcc055c646e030a806ccf029dcf77c0 318 SMART SM01130 7 306 5.3E-66 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS12785 1dcc055c646e030a806ccf029dcf77c0 318 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 139 169 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 CFK41_RS03975 5a2027395c21f10a689ce108eeb8a65c 171 Gene3D G3DSA:3.40.1000.10 20 159 1.2E-10 T 28-03-2018 CFK41_RS02145 4dfd9b734a6a26ed3040a0c322ce2e13 136 SUPERFAMILY SSF54593 1 124 2.59E-12 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS02145 4dfd9b734a6a26ed3040a0c322ce2e13 136 Gene3D G3DSA:3.10.180.10 1 128 2.6E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS16900 38c9b50c46103e26a75bbf2a4db1d109 248 Gene3D G3DSA:3.40.1410.10 89 243 1.8E-38 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CFK41_RS16900 38c9b50c46103e26a75bbf2a4db1d109 248 SUPERFAMILY SSF64288 71 244 1.27E-43 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CFK41_RS16900 38c9b50c46103e26a75bbf2a4db1d109 248 Gene3D G3DSA:1.10.10.10 6 88 2.2E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS16900 38c9b50c46103e26a75bbf2a4db1d109 248 SUPERFAMILY SSF46785 13 87 8.4E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS16900 38c9b50c46103e26a75bbf2a4db1d109 248 Pfam PF07702 UTRA domain 104 239 8.9E-33 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CFK41_RS16900 38c9b50c46103e26a75bbf2a4db1d109 248 SMART SM00866 103 240 1.0E-34 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CFK41_RS16900 38c9b50c46103e26a75bbf2a4db1d109 248 SMART SM00345 24 83 5.0E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS16900 38c9b50c46103e26a75bbf2a4db1d109 248 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 83 3.3E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS12675 9a0753176878e3f8c5b3612bfc5150ee 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 318 1.8E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS12675 9a0753176878e3f8c5b3612bfc5150ee 325 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 33 82 1.8E-7 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CFK41_RS12675 9a0753176878e3f8c5b3612bfc5150ee 325 SUPERFAMILY SSF161098 101 302 1.18E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS12675 9a0753176878e3f8c5b3612bfc5150ee 325 Gene3D G3DSA:1.10.3720.10 30 310 3.6E-35 T 28-03-2018 CFK41_RS14305 10f15dd08420d7e226212873d752acb5 359 Pfam PF00149 Calcineurin-like phosphoesterase 61 279 1.6E-12 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CFK41_RS14305 10f15dd08420d7e226212873d752acb5 359 SUPERFAMILY SSF56300 56 357 2.28E-49 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CFK41_RS14305 10f15dd08420d7e226212873d752acb5 359 Gene3D G3DSA:3.60.21.10 49 359 2.8E-50 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CFK41_RS07240 81ccba9e945c68b14388f1d27b77f12c 171 SUPERFAMILY SSF55021 83 163 4.27E-24 T 28-03-2018 CFK41_RS07240 81ccba9e945c68b14388f1d27b77f12c 171 Pfam PF10369 Small subunit of acetolactate synthase 87 160 4.6E-27 T 28-03-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CFK41_RS07240 81ccba9e945c68b14388f1d27b77f12c 171 Pfam PF13710 ACT domain 15 76 2.9E-15 T 28-03-2018 CFK41_RS07240 81ccba9e945c68b14388f1d27b77f12c 171 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 6 160 3.0E-56 T 28-03-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CFK41_RS07240 81ccba9e945c68b14388f1d27b77f12c 171 Gene3D G3DSA:3.30.70.1150 91 163 1.8E-27 T 28-03-2018 CFK41_RS07240 81ccba9e945c68b14388f1d27b77f12c 171 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 6 79 2.0E-27 T 28-03-2018 CFK41_RS07240 81ccba9e945c68b14388f1d27b77f12c 171 Gene3D G3DSA:3.30.70.260 1 90 3.5E-24 T 28-03-2018 CFK41_RS07240 81ccba9e945c68b14388f1d27b77f12c 171 SUPERFAMILY SSF55021 7 78 3.27E-21 T 28-03-2018 CFK41_RS08560 1fbe1d5648427d23e911365aef971cc3 208 Gene3D G3DSA:1.10.1050.10 143 208 4.3E-11 T 28-03-2018 CFK41_RS08560 1fbe1d5648427d23e911365aef971cc3 208 SUPERFAMILY SSF55174 11 208 9.55E-52 T 28-03-2018 CFK41_RS08560 1fbe1d5648427d23e911365aef971cc3 208 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 9 94 3.8E-19 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CFK41_RS08560 1fbe1d5648427d23e911365aef971cc3 208 Gene3D G3DSA:3.10.290.10 101 142 2.2E-15 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CFK41_RS08560 1fbe1d5648427d23e911365aef971cc3 208 SMART SM01390 8 94 2.5E-31 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CFK41_RS08560 1fbe1d5648427d23e911365aef971cc3 208 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 10 208 1.3E-61 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CFK41_RS08560 1fbe1d5648427d23e911365aef971cc3 208 SMART SM00363 95 157 2.8E-14 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CFK41_RS08560 1fbe1d5648427d23e911365aef971cc3 208 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 6 208 29.639 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CFK41_RS08560 1fbe1d5648427d23e911365aef971cc3 208 Gene3D G3DSA:1.10.1050.10 4 100 3.3E-30 T 28-03-2018 CFK41_RS08560 1fbe1d5648427d23e911365aef971cc3 208 Pfam PF01479 S4 domain 95 142 1.2E-16 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CFK41_RS06805 a4ee45fd0207efc2fa0fd76a1f4fdbaa 180 Pfam PF13279 Thioesterase-like superfamily 30 160 8.3E-20 T 28-03-2018 CFK41_RS06805 a4ee45fd0207efc2fa0fd76a1f4fdbaa 180 Gene3D G3DSA:3.10.129.10 21 171 6.4E-31 T 28-03-2018 CFK41_RS06805 a4ee45fd0207efc2fa0fd76a1f4fdbaa 180 SUPERFAMILY SSF54637 26 163 3.92E-31 T 28-03-2018 IPR029069 HotDog domain CFK41_RS03615 01874a9487cf671ec40d082ecc0c4e1a 267 ProSitePatterns PS00211 ABC transporters family signature. 176 190 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS03615 01874a9487cf671ec40d082ecc0c4e1a 267 Gene3D G3DSA:3.40.50.300 32 262 2.1E-57 T 28-03-2018 CFK41_RS03615 01874a9487cf671ec40d082ecc0c4e1a 267 Pfam PF00005 ABC transporter 55 203 7.4E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS03615 01874a9487cf671ec40d082ecc0c4e1a 267 SMART SM00382 64 254 2.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS03615 01874a9487cf671ec40d082ecc0c4e1a 267 SUPERFAMILY SSF52540 36 256 1.45E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS15720 6a5d77bc9fdde6c894cab848178d92f7 442 Gene3D G3DSA:3.90.1150.10 335 438 1.4E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS15720 6a5d77bc9fdde6c894cab848178d92f7 442 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 51 379 3.5E-53 T 28-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 CFK41_RS15720 6a5d77bc9fdde6c894cab848178d92f7 442 Gene3D G3DSA:3.40.640.10 74 334 7.9E-57 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS15720 6a5d77bc9fdde6c894cab848178d92f7 442 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 63 82 8.4E-6 T 28-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CFK41_RS15720 6a5d77bc9fdde6c894cab848178d92f7 442 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 362 381 8.4E-6 T 28-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CFK41_RS15720 6a5d77bc9fdde6c894cab848178d92f7 442 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 319 334 8.4E-6 T 28-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CFK41_RS15720 6a5d77bc9fdde6c894cab848178d92f7 442 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 103 122 8.4E-6 T 28-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CFK41_RS15720 6a5d77bc9fdde6c894cab848178d92f7 442 SUPERFAMILY SSF53383 14 431 2.02E-102 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS15720 6a5d77bc9fdde6c894cab848178d92f7 442 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 266 287 - T 28-03-2018 IPR021115 Pyridoxal-phosphate binding site GO:0016831 CFK41_RS02835 0ab241b948a2ca38a35b20c66d09b9fc 326 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 120 191 1.2E-21 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CFK41_RS02835 0ab241b948a2ca38a35b20c66d09b9fc 326 Gene3D G3DSA:3.40.47.10 174 326 1.1E-33 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CFK41_RS02835 0ab241b948a2ca38a35b20c66d09b9fc 326 Gene3D G3DSA:3.40.47.10 12 173 7.7E-41 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CFK41_RS02835 0ab241b948a2ca38a35b20c66d09b9fc 326 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 236 324 4.8E-29 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CFK41_RS02835 0ab241b948a2ca38a35b20c66d09b9fc 326 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 17 324 1.5E-94 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CFK41_RS02835 0ab241b948a2ca38a35b20c66d09b9fc 326 SUPERFAMILY SSF53901 14 325 1.15E-62 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CFK41_RS10150 3c3a00db337ba5a912e370480ef33a7e 232 Gene3D G3DSA:3.40.50.150 2 229 4.7E-39 T 28-03-2018 CFK41_RS10150 3c3a00db337ba5a912e370480ef33a7e 232 SUPERFAMILY SSF53335 4 226 1.45E-44 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS10150 3c3a00db337ba5a912e370480ef33a7e 232 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 4 229 31.977 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CFK41_RS10150 3c3a00db337ba5a912e370480ef33a7e 232 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 13 227 8.7E-64 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CFK41_RS10150 3c3a00db337ba5a912e370480ef33a7e 232 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 137 151 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CFK41_RS10150 3c3a00db337ba5a912e370480ef33a7e 232 Pfam PF01209 ubiE/COQ5 methyltransferase family 11 228 8.4E-56 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CFK41_RS12045 27a56b955a2d5674769a08014ca491a7 245 Pfam PF06182 ABC-2 family transporter protein 20 244 6.1E-16 T 28-03-2018 IPR010390 Protein of unknown function DUF990 CFK41_RS02225 9b1396720ab3f6291bdc8e19b60a6ea8 455 PIRSF PIRSF000726 60 447 2.0E-115 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CFK41_RS02225 9b1396720ab3f6291bdc8e19b60a6ea8 455 PIRSF PIRSF000726 1 62 8.6E-20 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CFK41_RS02225 9b1396720ab3f6291bdc8e19b60a6ea8 455 SUPERFAMILY SSF55021 284 363 7.45E-15 T 28-03-2018 CFK41_RS02225 9b1396720ab3f6291bdc8e19b60a6ea8 455 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CFK41_RS02225 9b1396720ab3f6291bdc8e19b60a6ea8 455 Gene3D G3DSA:3.30.70.260 366 455 2.3E-21 T 28-03-2018 CFK41_RS02225 9b1396720ab3f6291bdc8e19b60a6ea8 455 Pfam PF00696 Amino acid kinase family 3 231 3.5E-52 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CFK41_RS02225 9b1396720ab3f6291bdc8e19b60a6ea8 455 Gene3D G3DSA:3.40.1160.10 1 244 1.0E-70 T 28-03-2018 CFK41_RS02225 9b1396720ab3f6291bdc8e19b60a6ea8 455 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 1 439 8.9E-118 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CFK41_RS02225 9b1396720ab3f6291bdc8e19b60a6ea8 455 SUPERFAMILY SSF55021 366 442 9.16E-23 T 28-03-2018 CFK41_RS02225 9b1396720ab3f6291bdc8e19b60a6ea8 455 SUPERFAMILY SSF53633 4 244 4.32E-70 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CFK41_RS02225 9b1396720ab3f6291bdc8e19b60a6ea8 455 Gene3D G3DSA:3.30.70.260 281 365 5.9E-19 T 28-03-2018 CFK41_RS02225 9b1396720ab3f6291bdc8e19b60a6ea8 455 Pfam PF13840 ACT domain 374 435 5.8E-11 T 28-03-2018 IPR027795 GATS-like ACT domain CFK41_RS02225 9b1396720ab3f6291bdc8e19b60a6ea8 455 Pfam PF01842 ACT domain 303 362 4.2E-7 T 28-03-2018 IPR002912 ACT domain CFK41_RS08815 747701fa3ea196a784c6c17b24b68c8b 397 TIGRFAM TIGR02149 glgA_Coryne: glycogen synthase, Corynebacterium family 1 393 5.1E-171 T 28-03-2018 IPR011875 Alpha-maltose-1-phosphate synthase GO:0009250|GO:0016740 CFK41_RS08815 747701fa3ea196a784c6c17b24b68c8b 397 Gene3D G3DSA:3.40.50.2000 2 187 7.1E-19 T 28-03-2018 CFK41_RS08815 747701fa3ea196a784c6c17b24b68c8b 397 SUPERFAMILY SSF53756 9 395 6.28E-82 T 28-03-2018 CFK41_RS08815 747701fa3ea196a784c6c17b24b68c8b 397 Gene3D G3DSA:3.40.50.2000 188 375 2.8E-44 T 28-03-2018 CFK41_RS08815 747701fa3ea196a784c6c17b24b68c8b 397 Pfam PF13439 Glycosyltransferase Family 4 15 178 3.5E-26 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CFK41_RS08815 747701fa3ea196a784c6c17b24b68c8b 397 Pfam PF00534 Glycosyl transferases group 1 193 327 2.9E-29 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CFK41_RS17140 5052c31224f1a3604ad4a2fe873a5dd4 300 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 22 107 2.6E-6 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CFK41_RS17140 5052c31224f1a3604ad4a2fe873a5dd4 300 SUPERFAMILY SSF51735 22 183 3.51E-14 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS17140 5052c31224f1a3604ad4a2fe873a5dd4 300 Gene3D G3DSA:1.10.3640.10 193 292 1.8E-33 T 28-03-2018 IPR031663 Phosphogluconate dehydrogenase (decarboxylating) , C-terminal CFK41_RS17140 5052c31224f1a3604ad4a2fe873a5dd4 300 Gene3D G3DSA:3.40.50.720 19 192 8.5E-25 T 28-03-2018 CFK41_RS17140 5052c31224f1a3604ad4a2fe873a5dd4 300 Pfam PF16896 Phosphogluconate dehydrogenase (decarboxylating) C-term 140 293 4.7E-53 T 28-03-2018 IPR031663 Phosphogluconate dehydrogenase (decarboxylating) , C-terminal CFK41_RS10755 59c13654a5ad62555d0c5b1ae5c8ab31 193 Pfam PF13302 Acetyltransferase (GNAT) domain 20 151 1.3E-19 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS10755 59c13654a5ad62555d0c5b1ae5c8ab31 193 Gene3D G3DSA:3.40.630.30 7 170 4.5E-23 T 28-03-2018 CFK41_RS10755 59c13654a5ad62555d0c5b1ae5c8ab31 193 SUPERFAMILY SSF55729 13 152 6.34E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS02860 0238338e694b656473169c2384b98bbd 271 Pfam PF08241 Methyltransferase domain 69 157 1.5E-13 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CFK41_RS02860 0238338e694b656473169c2384b98bbd 271 SUPERFAMILY SSF53335 33 218 4.69E-26 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS02860 0238338e694b656473169c2384b98bbd 271 Gene3D G3DSA:3.40.50.150 19 235 4.6E-21 T 28-03-2018 CFK41_RS02005 74723cd8868cb2e2a2d3fb4d61859a83 264 Gene3D G3DSA:3.40.50.720 2 258 1.5E-19 T 28-03-2018 CFK41_RS02005 74723cd8868cb2e2a2d3fb4d61859a83 264 SUPERFAMILY SSF51735 2 255 2.15E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS12935 cf4c82a0cd1366ee3e1e066213e827dd 239 Gene3D G3DSA:1.10.10.10 134 239 1.5E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS12935 cf4c82a0cd1366ee3e1e066213e827dd 239 SMART SM00448 11 122 2.0E-46 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS12935 cf4c82a0cd1366ee3e1e066213e827dd 239 SUPERFAMILY SSF52172 10 133 3.56E-42 T 28-03-2018 IPR011006 CheY-like superfamily CFK41_RS12935 cf4c82a0cd1366ee3e1e066213e827dd 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 161 233 1.1E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CFK41_RS12935 cf4c82a0cd1366ee3e1e066213e827dd 239 SUPERFAMILY SSF46894 138 234 3.4E-27 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CFK41_RS12935 cf4c82a0cd1366ee3e1e066213e827dd 239 Pfam PF00072 Response regulator receiver domain 14 123 3.7E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS12935 cf4c82a0cd1366ee3e1e066213e827dd 239 Gene3D G3DSA:3.40.50.2300 1 133 1.1E-39 T 28-03-2018 CFK41_RS12935 cf4c82a0cd1366ee3e1e066213e827dd 239 SMART SM00862 159 233 6.3E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CFK41_RS14420 8754877c38594b403b14e3e5c249deb0 71 SUPERFAMILY SSF51569 6 68 1.86E-6 T 28-03-2018 CFK41_RS14420 8754877c38594b403b14e3e5c249deb0 71 Gene3D G3DSA:3.20.20.70 2 71 6.5E-9 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS14420 8754877c38594b403b14e3e5c249deb0 71 Pfam PF01116 Fructose-bisphosphate aldolase class-II 6 67 3.3E-7 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CFK41_RS13165 8523d7dfd1bf2413e4a75679eb62693b 491 PIRSF PIRSF000362 2 484 3.6E-149 T 28-03-2018 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CFK41_RS13165 8523d7dfd1bf2413e4a75679eb62693b 491 SUPERFAMILY SSF51971 327 460 7.06E-7 T 28-03-2018 CFK41_RS13165 8523d7dfd1bf2413e4a75679eb62693b 491 PRINTS PR00419 Adrenodoxin reductase family signature 154 168 1.8E-14 T 28-03-2018 CFK41_RS13165 8523d7dfd1bf2413e4a75679eb62693b 491 PRINTS PR00419 Adrenodoxin reductase family signature 83 93 1.8E-14 T 28-03-2018 CFK41_RS13165 8523d7dfd1bf2413e4a75679eb62693b 491 PRINTS PR00419 Adrenodoxin reductase family signature 9 31 1.8E-14 T 28-03-2018 CFK41_RS13165 8523d7dfd1bf2413e4a75679eb62693b 491 Gene3D G3DSA:3.40.50.720 1 112 1.6E-9 T 28-03-2018 CFK41_RS13165 8523d7dfd1bf2413e4a75679eb62693b 491 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 176 2.2E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS13165 8523d7dfd1bf2413e4a75679eb62693b 491 Gene3D G3DSA:3.50.50.60 113 344 4.7E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS13165 8523d7dfd1bf2413e4a75679eb62693b 491 SUPERFAMILY SSF51971 7 220 5.77E-52 T 28-03-2018 CFK41_RS13165 8523d7dfd1bf2413e4a75679eb62693b 491 SUPERFAMILY SSF51971 284 344 5.77E-52 T 28-03-2018 CFK41_RS14515 0bc62cf87c8342e8ec81922f78407452 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 289 1.2E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS14515 0bc62cf87c8342e8ec81922f78407452 296 Gene3D G3DSA:1.10.3720.10 29 286 3.5E-47 T 28-03-2018 CFK41_RS14515 0bc62cf87c8342e8ec81922f78407452 296 SUPERFAMILY SSF161098 23 296 2.9E-71 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS13515 ec267653524b3b12b6646e8799027f31 135 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 70 1.2E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS13515 ec267653524b3b12b6646e8799027f31 135 SMART SM00345 11 70 8.1E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS13515 ec267653524b3b12b6646e8799027f31 135 Gene3D G3DSA:1.10.10.10 1 72 1.6E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS13515 ec267653524b3b12b6646e8799027f31 135 SUPERFAMILY SSF46785 2 78 1.36E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS14405 2b9a70a513ed6ba854e3fe950bb737e9 333 Pfam PF13011 leucine-zipper of insertion element IS481 1 69 1.8E-13 T 28-03-2018 IPR024967 DNA-binding domain, IS481-type CFK41_RS14405 2b9a70a513ed6ba854e3fe950bb737e9 333 Gene3D G3DSA:1.10.10.10 9 69 3.3E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS14405 2b9a70a513ed6ba854e3fe950bb737e9 333 Pfam PF00665 Integrase core domain 142 278 8.8E-21 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CFK41_RS14405 2b9a70a513ed6ba854e3fe950bb737e9 333 Gene3D G3DSA:3.30.420.10 135 328 4.0E-28 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CFK41_RS14405 2b9a70a513ed6ba854e3fe950bb737e9 333 Gene3D G3DSA:1.10.10.60 74 120 6.9E-4 T 28-03-2018 CFK41_RS14405 2b9a70a513ed6ba854e3fe950bb737e9 333 SUPERFAMILY SSF53098 181 322 2.02E-26 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CFK41_RS14405 2b9a70a513ed6ba854e3fe950bb737e9 333 SUPERFAMILY SSF53098 141 153 2.02E-26 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CFK41_RS14405 2b9a70a513ed6ba854e3fe950bb737e9 333 SUPERFAMILY SSF46689 2 117 2.69E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS14765 05eba151a8f722a791af444bfb9e277d 463 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 199 431 7.1E-60 T 28-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 CFK41_RS14765 05eba151a8f722a791af444bfb9e277d 463 PRINTS PR00732 Glycosyl hydrolase family 4 signature 79 95 5.5E-26 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CFK41_RS14765 05eba151a8f722a791af444bfb9e277d 463 PRINTS PR00732 Glycosyl hydrolase family 4 signature 195 207 5.5E-26 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CFK41_RS14765 05eba151a8f722a791af444bfb9e277d 463 PRINTS PR00732 Glycosyl hydrolase family 4 signature 145 162 5.5E-26 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CFK41_RS14765 05eba151a8f722a791af444bfb9e277d 463 PRINTS PR00732 Glycosyl hydrolase family 4 signature 116 136 5.5E-26 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CFK41_RS14765 05eba151a8f722a791af444bfb9e277d 463 PRINTS PR00732 Glycosyl hydrolase family 4 signature 100 113 5.5E-26 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CFK41_RS14765 05eba151a8f722a791af444bfb9e277d 463 PRINTS PR00732 Glycosyl hydrolase family 4 signature 10 25 5.5E-26 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CFK41_RS14765 05eba151a8f722a791af444bfb9e277d 463 Gene3D G3DSA:3.90.1820.10 319 462 3.1E-36 T 28-03-2018 CFK41_RS14765 05eba151a8f722a791af444bfb9e277d 463 Gene3D G3DSA:3.90.1820.10 6 318 3.9E-67 T 28-03-2018 CFK41_RS14765 05eba151a8f722a791af444bfb9e277d 463 Pfam PF02056 Family 4 glycosyl hydrolase 10 189 1.0E-49 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CFK41_RS14765 05eba151a8f722a791af444bfb9e277d 463 SUPERFAMILY SSF56327 173 458 3.21E-60 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CFK41_RS14765 05eba151a8f722a791af444bfb9e277d 463 SUPERFAMILY SSF51735 8 164 9.18E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS08030 a175759d2f84b8a5174e386f358e04d1 413 Gene3D G3DSA:3.40.630.30 2 134 2.5E-13 T 28-03-2018 CFK41_RS08030 a175759d2f84b8a5174e386f358e04d1 413 Pfam PF13530 Sterol carrier protein domain 184 407 4.2E-20 T 28-03-2018 IPR025559 Enhanced intracellular survival protein domain CFK41_RS08030 a175759d2f84b8a5174e386f358e04d1 413 Pfam PF13527 Acetyltransferase (GNAT) domain 3 133 3.3E-17 T 28-03-2018 CFK41_RS08030 a175759d2f84b8a5174e386f358e04d1 413 Gene3D G3DSA:3.30.1050.10 286 407 1.8E-17 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CFK41_RS08030 a175759d2f84b8a5174e386f358e04d1 413 SUPERFAMILY SSF55718 295 413 2.83E-7 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CFK41_RS08030 a175759d2f84b8a5174e386f358e04d1 413 Gene3D G3DSA:3.40.630.30 135 285 3.5E-21 T 28-03-2018 CFK41_RS08030 a175759d2f84b8a5174e386f358e04d1 413 SUPERFAMILY SSF55729 1 294 1.99E-38 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS10365 60ebbe9959495aa52df028a321a392d2 220 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 68 207 1.4E-25 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CFK41_RS10365 60ebbe9959495aa52df028a321a392d2 220 SUPERFAMILY SSF100950 9 212 6.7E-29 T 28-03-2018 CFK41_RS10365 60ebbe9959495aa52df028a321a392d2 220 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 32 207 2.6E-23 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CFK41_RS10365 60ebbe9959495aa52df028a321a392d2 220 PIRSF PIRSF006806 55 211 1.4E-21 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CFK41_RS10365 60ebbe9959495aa52df028a321a392d2 220 PIRSF PIRSF006806 5 26 1100.0 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CFK41_RS10365 60ebbe9959495aa52df028a321a392d2 220 Gene3D G3DSA:3.40.50.10420 1 213 4.3E-41 T 28-03-2018 CFK41_RS11055 56547c42f408d9a5596cd2386d293fcc 658 SMART SM00382 3 205 4.4E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS11055 56547c42f408d9a5596cd2386d293fcc 658 SMART SM00382 247 414 2.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS11055 56547c42f408d9a5596cd2386d293fcc 658 Gene3D G3DSA:3.40.50.300 238 410 2.9E-42 T 28-03-2018 CFK41_RS11055 56547c42f408d9a5596cd2386d293fcc 658 SUPERFAMILY SSF52540 1 199 2.37E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11055 56547c42f408d9a5596cd2386d293fcc 658 Pfam PF00005 ABC transporter 242 366 7.2E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS11055 56547c42f408d9a5596cd2386d293fcc 658 Pfam PF00005 ABC transporter 1 134 7.3E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS11055 56547c42f408d9a5596cd2386d293fcc 658 SUPERFAMILY SSF52540 237 408 4.64E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11055 56547c42f408d9a5596cd2386d293fcc 658 ProSitePatterns PS00211 ABC transporters family signature. 106 120 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS11055 56547c42f408d9a5596cd2386d293fcc 658 Gene3D G3DSA:3.40.50.300 1 219 4.8E-39 T 28-03-2018 CFK41_RS11055 56547c42f408d9a5596cd2386d293fcc 658 ProSitePatterns PS00211 ABC transporters family signature. 339 353 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS02215 97b13ad7000fc1c83858d283d10785c6 787 SUPERFAMILY SSF52402 724 753 3.45E-63 T 28-03-2018 CFK41_RS02215 97b13ad7000fc1c83858d283d10785c6 787 SUPERFAMILY SSF52402 428 683 3.45E-63 T 28-03-2018 CFK41_RS02215 97b13ad7000fc1c83858d283d10785c6 787 Gene3D G3DSA:3.40.50.620 458 778 3.9E-52 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS02215 97b13ad7000fc1c83858d283d10785c6 787 Gene3D G3DSA:3.60.110.10 45 457 1.1E-79 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CFK41_RS02215 97b13ad7000fc1c83858d283d10785c6 787 PIRSF PIRSF006630 51 777 7.7E-153 T 28-03-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CFK41_RS02215 97b13ad7000fc1c83858d283d10785c6 787 Pfam PF02540 NAD synthase 471 680 8.1E-19 T 28-03-2018 IPR022310 NAD/GMP synthase CFK41_RS02215 97b13ad7000fc1c83858d283d10785c6 787 SUPERFAMILY SSF56317 52 342 3.4E-52 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CFK41_RS02215 97b13ad7000fc1c83858d283d10785c6 787 Pfam PF00795 Carbon-nitrogen hydrolase 55 324 6.9E-17 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CFK41_RS10495 a2413260c441531ab88590088003de37 284 Gene3D G3DSA:3.20.20.20 8 283 8.3E-93 T 28-03-2018 CFK41_RS10495 a2413260c441531ab88590088003de37 284 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 55 68 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CFK41_RS10495 a2413260c441531ab88590088003de37 284 Pfam PF00809 Pterin binding enzyme 22 263 2.4E-72 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CFK41_RS10495 a2413260c441531ab88590088003de37 284 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 21 36 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CFK41_RS10495 a2413260c441531ab88590088003de37 284 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 21 276 6.3E-79 T 28-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 CFK41_RS10495 a2413260c441531ab88590088003de37 284 SUPERFAMILY SSF51717 16 280 1.03E-78 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CFK41_RS08310 05cc930042646a4323b97c68ed8b4301 390 Pfam PF07730 Histidine kinase 200 264 3.4E-13 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CFK41_RS08310 05cc930042646a4323b97c68ed8b4301 390 SUPERFAMILY SSF55874 278 388 2.71E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS08310 05cc930042646a4323b97c68ed8b4301 390 Gene3D G3DSA:3.30.565.10 180 390 5.7E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS03015 5e06528dbfce24afbfd6e552512063fe 173 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 81 169 1.6E-16 T 28-03-2018 IPR032030 YscD, cytoplasmic domain CFK41_RS03015 5e06528dbfce24afbfd6e552512063fe 173 SUPERFAMILY SSF49879 70 169 2.49E-26 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 CFK41_RS03015 5e06528dbfce24afbfd6e552512063fe 173 SMART SM00240 97 147 1.3E-11 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CFK41_RS03015 5e06528dbfce24afbfd6e552512063fe 173 Gene3D G3DSA:2.60.200.20 61 171 1.2E-25 T 28-03-2018 CFK41_RS00715 44bee1300888e0dbb662e017a761aa17 204 SUPERFAMILY SSF46689 9 91 1.59E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS00715 44bee1300888e0dbb662e017a761aa17 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 67 1.5E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS00715 44bee1300888e0dbb662e017a761aa17 204 Gene3D G3DSA:1.10.260.40 49 70 5.3E-9 T 28-03-2018 CFK41_RS00715 44bee1300888e0dbb662e017a761aa17 204 Gene3D G3DSA:1.10.10.60 6 48 1.0E-11 T 28-03-2018 CFK41_RS00715 44bee1300888e0dbb662e017a761aa17 204 Gene3D G3DSA:1.10.357.10 71 195 3.3E-8 T 28-03-2018 CFK41_RS13945 21a66e751af70de448eaa422bdc77651 549 Gene3D G3DSA:3.40.275.10 210 338 5.7E-31 T 28-03-2018 CFK41_RS13945 21a66e751af70de448eaa422bdc77651 549 Gene3D G3DSA:3.40.50.1070 25 176 2.8E-30 T 28-03-2018 CFK41_RS13945 21a66e751af70de448eaa422bdc77651 549 SUPERFAMILY SSF53743 25 157 6.37E-47 T 28-03-2018 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 CFK41_RS13945 21a66e751af70de448eaa422bdc77651 549 SUPERFAMILY SSF53743 189 374 6.37E-47 T 28-03-2018 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 CFK41_RS13945 21a66e751af70de448eaa422bdc77651 549 Pfam PF02952 L-fucose isomerase, C-terminal domain 428 515 4.6E-8 T 28-03-2018 IPR015888 L-fucose isomerase, C-terminal GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 CFK41_RS13945 21a66e751af70de448eaa422bdc77651 549 Gene3D G3DSA:3.20.14.10 409 541 3.5E-28 T 28-03-2018 CFK41_RS11860 691edcbe096ce726e6ddcb5b22cad260 408 Pfam PF02481 DNA recombination-mediator protein A 108 319 3.2E-69 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CFK41_RS11860 691edcbe096ce726e6ddcb5b22cad260 408 Gene3D G3DSA:3.40.50.450 143 301 1.2E-38 T 28-03-2018 CFK41_RS11860 691edcbe096ce726e6ddcb5b22cad260 408 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 107 327 6.0E-65 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CFK41_RS11860 691edcbe096ce726e6ddcb5b22cad260 408 Gene3D G3DSA:1.10.10.10 342 408 2.7E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS11860 691edcbe096ce726e6ddcb5b22cad260 408 SUPERFAMILY SSF102405 118 328 3.2E-31 T 28-03-2018 CFK41_RS06355 9e7d573d74a4e3c722a478727ffb78ba 223 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 104 5.9E-22 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CFK41_RS06355 9e7d573d74a4e3c722a478727ffb78ba 223 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 218 22.52 T 28-03-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid CFK41_RS06355 9e7d573d74a4e3c722a478727ffb78ba 223 SUPERFAMILY SSF69754 1 105 4.32E-23 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CFK41_RS06355 9e7d573d74a4e3c722a478727ffb78ba 223 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 99 5.1E-18 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CFK41_RS06355 9e7d573d74a4e3c722a478727ffb78ba 223 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 160 214 8.3E-23 T 28-03-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal CFK41_RS06355 9e7d573d74a4e3c722a478727ffb78ba 223 Gene3D G3DSA:3.30.160.100 1 102 3.8E-21 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CFK41_RS17040 fb71981170b003542815636338310c78 322 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 15 315 1.3E-31 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CFK41_RS17040 fb71981170b003542815636338310c78 322 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 282 2.8E-53 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CFK41_RS17040 fb71981170b003542815636338310c78 322 SUPERFAMILY SSF51735 101 285 3.11E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS17040 fb71981170b003542815636338310c78 322 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 193 215 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CFK41_RS17040 fb71981170b003542815636338310c78 322 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 222 238 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CFK41_RS17040 fb71981170b003542815636338310c78 322 Gene3D G3DSA:3.40.50.720 114 286 2.3E-51 T 28-03-2018 CFK41_RS17040 fb71981170b003542815636338310c78 322 SUPERFAMILY SSF52283 1 121 6.24E-31 T 28-03-2018 CFK41_RS17040 fb71981170b003542815636338310c78 322 Gene3D G3DSA:3.40.50.720 1 113 3.3E-34 T 28-03-2018 CFK41_RS12480 eec1ed1a2a6616fc8486198a858f336d 248 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 4 247 2.1E-111 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CFK41_RS12480 eec1ed1a2a6616fc8486198a858f336d 248 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 131 2.6E-28 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CFK41_RS12480 eec1ed1a2a6616fc8486198a858f336d 248 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 143 214 3.7E-5 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CFK41_RS12480 eec1ed1a2a6616fc8486198a858f336d 248 SUPERFAMILY SSF53254 1 221 1.08E-71 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CFK41_RS12480 eec1ed1a2a6616fc8486198a858f336d 248 Gene3D G3DSA:3.40.50.1240 1 248 2.6E-63 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CFK41_RS12480 eec1ed1a2a6616fc8486198a858f336d 248 PIRSF PIRSF000709 3 115 1.0E-7 T 28-03-2018 CFK41_RS12480 eec1ed1a2a6616fc8486198a858f336d 248 PIRSF PIRSF000709 130 224 0.014 T 28-03-2018 CFK41_RS12480 eec1ed1a2a6616fc8486198a858f336d 248 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 7 16 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CFK41_RS12480 eec1ed1a2a6616fc8486198a858f336d 248 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 2 230 42.637 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CFK41_RS12480 eec1ed1a2a6616fc8486198a858f336d 248 SMART SM00855 4 189 4.5E-23 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CFK41_RS15960 8cf9c9a964f052c4f62e91c1b1afdb3e 553 Gene3D G3DSA:3.40.190.10 225 551 5.5E-24 T 28-03-2018 CFK41_RS15960 8cf9c9a964f052c4f62e91c1b1afdb3e 553 SUPERFAMILY SSF53850 100 549 4.51E-48 T 28-03-2018 CFK41_RS15960 8cf9c9a964f052c4f62e91c1b1afdb3e 553 Pfam PF01547 Bacterial extracellular solute-binding protein 137 409 3.6E-8 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CFK41_RS15225 c878120ab89aaf2b8476255cabc864ad 325 Gene3D G3DSA:1.20.58.370 20 60 8.4E-5 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CFK41_RS15225 c878120ab89aaf2b8476255cabc864ad 325 SUPERFAMILY SSF161098 77 310 3.53E-51 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS15225 c878120ab89aaf2b8476255cabc864ad 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 317 1.8E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS15225 c878120ab89aaf2b8476255cabc864ad 325 Gene3D G3DSA:1.10.3720.10 87 319 2.3E-40 T 28-03-2018 CFK41_RS01360 13dc1c3f4f717e4c38ea1f3223a70f3c 430 Gene3D G3DSA:3.40.190.10 22 174 3.1E-20 T 28-03-2018 CFK41_RS01360 13dc1c3f4f717e4c38ea1f3223a70f3c 430 Gene3D G3DSA:3.40.190.10 175 379 1.8E-9 T 28-03-2018 CFK41_RS01360 13dc1c3f4f717e4c38ea1f3223a70f3c 430 Pfam PF13416 Bacterial extracellular solute-binding protein 50 349 3.6E-21 T 28-03-2018 CFK41_RS01360 13dc1c3f4f717e4c38ea1f3223a70f3c 430 SUPERFAMILY SSF53850 22 421 3.56E-48 T 28-03-2018 CFK41_RS11535 ca9908edec5c26c6eccf4336d6ced338 143 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 138 1.3E-39 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CFK41_RS11535 ca9908edec5c26c6eccf4336d6ced338 143 Gene3D G3DSA:2.10.260.10 79 125 8.1E-6 T 28-03-2018 CFK41_RS11535 ca9908edec5c26c6eccf4336d6ced338 143 Gene3D G3DSA:2.10.260.10 1 78 2.9E-4 T 28-03-2018 CFK41_RS11535 ca9908edec5c26c6eccf4336d6ced338 143 Pfam PF02381 MraZ protein, putative antitoxin-like 1 70 3.5E-18 T 28-03-2018 IPR020603 MraZ domain CFK41_RS11535 ca9908edec5c26c6eccf4336d6ced338 143 Pfam PF02381 MraZ protein, putative antitoxin-like 72 137 3.0E-19 T 28-03-2018 IPR020603 MraZ domain CFK41_RS11535 ca9908edec5c26c6eccf4336d6ced338 143 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 128 4.0E-43 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CFK41_RS11535 ca9908edec5c26c6eccf4336d6ced338 143 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 143 47.631 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CFK41_RS11535 ca9908edec5c26c6eccf4336d6ced338 143 SUPERFAMILY SSF89447 1 135 1.79E-43 T 28-03-2018 CFK41_RS13230 9c5b9d4592cdd4d2a05b81998a8b53c9 218 Pfam PF10756 Bacterial PH domain 128 187 6.4E-9 T 28-03-2018 IPR019692 Protein of unknown function DUF2581 CFK41_RS14415 6f0f9727b4ff93e87058821c5212c713 674 SUPERFAMILY SSF52540 154 231 3.29E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS14415 6f0f9727b4ff93e87058821c5212c713 674 SUPERFAMILY SSF52540 447 660 3.29E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS14415 6f0f9727b4ff93e87058821c5212c713 674 SUPERFAMILY SSF52540 291 359 3.29E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS14415 6f0f9727b4ff93e87058821c5212c713 674 Pfam PF13245 AAA domain 165 499 5.1E-12 T 28-03-2018 CFK41_RS14415 6f0f9727b4ff93e87058821c5212c713 674 Gene3D G3DSA:3.40.50.300 159 513 6.5E-30 T 28-03-2018 CFK41_RS14415 6f0f9727b4ff93e87058821c5212c713 674 Pfam PF13538 UvrD-like helicase C-terminal domain 621 660 7.4E-7 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain CFK41_RS14415 6f0f9727b4ff93e87058821c5212c713 674 Gene3D G3DSA:3.40.50.300 525 671 2.0E-13 T 28-03-2018 CFK41_RS03290 85c005c490f4534861dd5ce068e1627a 697 Gene3D G3DSA:3.90.550.10 2 278 1.1E-46 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS03290 85c005c490f4534861dd5ce068e1627a 697 Pfam PF00535 Glycosyl transferase family 2 13 173 1.9E-32 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CFK41_RS03290 85c005c490f4534861dd5ce068e1627a 697 SUPERFAMILY SSF53448 10 222 1.29E-48 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS16945 dde9696653144a1d6fe01f42dd4856fe 319 Pfam PF01261 Xylose isomerase-like TIM barrel 53 238 6.0E-28 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS16945 dde9696653144a1d6fe01f42dd4856fe 319 SUPERFAMILY SSF51658 20 298 5.25E-48 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS16945 dde9696653144a1d6fe01f42dd4856fe 319 Gene3D G3DSA:3.20.20.150 17 313 6.6E-49 T 28-03-2018 CFK41_RS03740 e6d21342c51e499aa89babbaabc57734 334 SUPERFAMILY SSF53067 134 330 2.41E-25 T 28-03-2018 CFK41_RS03740 e6d21342c51e499aa89babbaabc57734 334 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 21 200 2.7E-16 T 28-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 CFK41_RS03740 e6d21342c51e499aa89babbaabc57734 334 Gene3D G3DSA:3.30.420.40 10 148 1.3E-15 T 28-03-2018 CFK41_RS03740 e6d21342c51e499aa89babbaabc57734 334 Gene3D G3DSA:3.30.420.40 149 306 7.5E-35 T 28-03-2018 CFK41_RS03740 e6d21342c51e499aa89babbaabc57734 334 SUPERFAMILY SSF53067 16 129 3.67E-11 T 28-03-2018 CFK41_RS01765 62952c21a7d099e4e339a05513456aaa 461 SMART SM00656 119 374 6.1E-41 T 28-03-2018 IPR002022 Pectate lyase CFK41_RS01765 62952c21a7d099e4e339a05513456aaa 461 Gene3D G3DSA:2.160.20.10 42 446 2.8E-71 T 28-03-2018 IPR012334 Pectin lyase fold CFK41_RS01765 62952c21a7d099e4e339a05513456aaa 461 SUPERFAMILY SSF51126 156 377 5.76E-62 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CFK41_RS01765 62952c21a7d099e4e339a05513456aaa 461 SUPERFAMILY SSF51126 51 112 5.76E-62 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CFK41_RS01765 62952c21a7d099e4e339a05513456aaa 461 Pfam PF00544 Pectate lyase 153 368 1.3E-46 T 28-03-2018 IPR002022 Pectate lyase CFK41_RS05580 f0c53bcaf3739e7216e1fed5718edbe7 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 3.4E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CFK41_RS05580 f0c53bcaf3739e7216e1fed5718edbe7 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 109 122 3.4E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CFK41_RS05580 f0c53bcaf3739e7216e1fed5718edbe7 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 3.4E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CFK41_RS05580 f0c53bcaf3739e7216e1fed5718edbe7 262 Gene3D G3DSA:3.40.50.1820 6 262 1.1E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS05580 f0c53bcaf3739e7216e1fed5718edbe7 262 Pfam PF00561 alpha/beta hydrolase fold 22 126 1.2E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CFK41_RS05580 f0c53bcaf3739e7216e1fed5718edbe7 262 SUPERFAMILY SSF53474 8 261 3.68E-52 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS01120 f6b7884717dcb9084b131f927aa40ad0 290 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 4 284 32.045 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CFK41_RS01120 f6b7884717dcb9084b131f927aa40ad0 290 Gene3D G3DSA:3.10.20.10 32 127 2.3E-28 T 28-03-2018 CFK41_RS01120 f6b7884717dcb9084b131f927aa40ad0 290 Pfam PF02634 FdhD/NarQ family 30 283 5.0E-73 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CFK41_RS01120 f6b7884717dcb9084b131f927aa40ad0 290 PIRSF PIRSF015626 1 286 3.0E-77 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CFK41_RS01120 f6b7884717dcb9084b131f927aa40ad0 290 Gene3D G3DSA:3.40.140.10 142 287 1.1E-51 T 28-03-2018 CFK41_RS01120 f6b7884717dcb9084b131f927aa40ad0 290 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 26 283 1.1E-51 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CFK41_RS01120 f6b7884717dcb9084b131f927aa40ad0 290 SUPERFAMILY SSF53927 11 283 3.61E-71 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CFK41_RS17065 bcaaee52b9aadb7d55c62d92f65fa2e2 348 SUPERFAMILY SSF51735 143 303 1.78E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS17065 bcaaee52b9aadb7d55c62d92f65fa2e2 348 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 334 348 3.6E-5 T 28-03-2018 CFK41_RS17065 bcaaee52b9aadb7d55c62d92f65fa2e2 348 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 167 189 3.6E-5 T 28-03-2018 CFK41_RS17065 bcaaee52b9aadb7d55c62d92f65fa2e2 348 Gene3D G3DSA:3.40.50.720 168 285 2.0E-27 T 28-03-2018 CFK41_RS17065 bcaaee52b9aadb7d55c62d92f65fa2e2 348 Gene3D G3DSA:3.90.180.10 1 167 7.5E-33 T 28-03-2018 CFK41_RS17065 bcaaee52b9aadb7d55c62d92f65fa2e2 348 SMART SM00829 7 339 0.0011 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CFK41_RS17065 bcaaee52b9aadb7d55c62d92f65fa2e2 348 SUPERFAMILY SSF50129 2 174 8.67E-37 T 28-03-2018 IPR011032 GroES-like CFK41_RS17065 bcaaee52b9aadb7d55c62d92f65fa2e2 348 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CFK41_RS17065 bcaaee52b9aadb7d55c62d92f65fa2e2 348 Pfam PF00107 Zinc-binding dehydrogenase 175 300 6.2E-18 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CFK41_RS17065 bcaaee52b9aadb7d55c62d92f65fa2e2 348 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 133 3.9E-17 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CFK41_RS12640 907ddfd3cfefb7c6f29079449999a80c 182 SUPERFAMILY SSF53218 28 175 9.16E-37 T 28-03-2018 IPR001453 MoaB/Mog domain CFK41_RS12640 907ddfd3cfefb7c6f29079449999a80c 182 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 30 162 1.2E-25 T 28-03-2018 IPR001453 MoaB/Mog domain CFK41_RS12640 907ddfd3cfefb7c6f29079449999a80c 182 Pfam PF00994 Probable molybdopterin binding domain 31 171 2.0E-28 T 28-03-2018 IPR001453 MoaB/Mog domain CFK41_RS12640 907ddfd3cfefb7c6f29079449999a80c 182 SMART SM00852 30 172 1.0E-14 T 28-03-2018 IPR001453 MoaB/Mog domain CFK41_RS12640 907ddfd3cfefb7c6f29079449999a80c 182 Gene3D G3DSA:3.40.980.10 7 173 1.3E-34 T 28-03-2018 IPR001453 MoaB/Mog domain CFK41_RS09145 9408aa805263f1dff7937a657e83c538 168 Gene3D G3DSA:3.90.79.10 11 163 7.5E-29 T 28-03-2018 CFK41_RS09145 9408aa805263f1dff7937a657e83c538 168 Pfam PF00293 NUDIX domain 32 154 4.3E-19 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CFK41_RS09145 9408aa805263f1dff7937a657e83c538 168 SUPERFAMILY SSF55811 21 154 2.44E-26 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CFK41_RS04020 661e336bccebe9a6d139238059782a47 94 Pfam PF04226 Transglycosylase associated protein 37 91 5.8E-8 T 28-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 CFK41_RS16190 b7e000c20d16b1ff6e4e7d32a9c1109f 303 Gene3D G3DSA:3.40.50.620 7 111 9.1E-25 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS16190 b7e000c20d16b1ff6e4e7d32a9c1109f 303 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 23 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS16190 b7e000c20d16b1ff6e4e7d32a9c1109f 303 SUPERFAMILY SSF52374 8 261 7.24E-70 T 28-03-2018 CFK41_RS16190 b7e000c20d16b1ff6e4e7d32a9c1109f 303 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 9 256 7.4E-44 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CFK41_RS16190 b7e000c20d16b1ff6e4e7d32a9c1109f 303 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 7 260 2.0E-84 T 28-03-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 CFK41_RS16190 b7e000c20d16b1ff6e4e7d32a9c1109f 303 PRINTS PR00987 Glutamyl-tRNA synthetase signature 38 51 7.5E-12 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CFK41_RS16190 b7e000c20d16b1ff6e4e7d32a9c1109f 303 PRINTS PR00987 Glutamyl-tRNA synthetase signature 183 193 7.5E-12 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CFK41_RS16190 b7e000c20d16b1ff6e4e7d32a9c1109f 303 PRINTS PR00987 Glutamyl-tRNA synthetase signature 9 21 7.5E-12 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CFK41_RS16190 b7e000c20d16b1ff6e4e7d32a9c1109f 303 PRINTS PR00987 Glutamyl-tRNA synthetase signature 23 34 7.5E-12 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CFK41_RS16190 b7e000c20d16b1ff6e4e7d32a9c1109f 303 Gene3D G3DSA:3.40.50.620 112 235 1.8E-28 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS02930 4a45399cf7c7c856e2464c3b8f65794f 257 SUPERFAMILY SSF52317 1 229 5.04E-56 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS02930 4a45399cf7c7c856e2464c3b8f65794f 257 Pfam PF06283 Trehalose utilisation 7 225 7.4E-31 T 28-03-2018 IPR029010 ThuA-like domain CFK41_RS02930 4a45399cf7c7c856e2464c3b8f65794f 257 PIRSF PIRSF030013 1 244 8.2E-100 T 28-03-2018 IPR009381 Trehalose catabolism protein, ThuA, prokaryote CFK41_RS02930 4a45399cf7c7c856e2464c3b8f65794f 257 Gene3D G3DSA:3.40.50.880 1 245 4.3E-47 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS04935 f940a732de9186d1d5693a3e803a8bfb 234 Gene3D G3DSA:3.30.420.40 1 149 6.1E-31 T 28-03-2018 CFK41_RS04935 f940a732de9186d1d5693a3e803a8bfb 234 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 2 218 4.6E-48 T 28-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 CFK41_RS04935 f940a732de9186d1d5693a3e803a8bfb 234 Pfam PF00814 Glycoprotease family 36 159 3.9E-26 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CFK41_RS04935 f940a732de9186d1d5693a3e803a8bfb 234 SUPERFAMILY SSF53067 121 216 3.5E-14 T 28-03-2018 CFK41_RS04935 f940a732de9186d1d5693a3e803a8bfb 234 SUPERFAMILY SSF53067 1 107 2.01E-20 T 28-03-2018 CFK41_RS02750 a16a45b9fdc6ecb34dcddf863974672b 827 Gene3D G3DSA:3.90.780.10 375 590 7.4E-45 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CFK41_RS02750 a16a45b9fdc6ecb34dcddf863974672b 827 PRINTS PR01607 Apyrase family signature 523 542 5.5E-16 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CFK41_RS02750 a16a45b9fdc6ecb34dcddf863974672b 827 PRINTS PR01607 Apyrase family signature 242 265 5.5E-16 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CFK41_RS02750 a16a45b9fdc6ecb34dcddf863974672b 827 PRINTS PR01607 Apyrase family signature 42 60 5.5E-16 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CFK41_RS02750 a16a45b9fdc6ecb34dcddf863974672b 827 PRINTS PR01607 Apyrase family signature 208 225 5.5E-16 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CFK41_RS02750 a16a45b9fdc6ecb34dcddf863974672b 827 PRINTS PR01607 Apyrase family signature 441 464 5.5E-16 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CFK41_RS02750 a16a45b9fdc6ecb34dcddf863974672b 827 SUPERFAMILY SSF55816 385 573 5.23E-40 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CFK41_RS02750 a16a45b9fdc6ecb34dcddf863974672b 827 Pfam PF02872 5'-nucleotidase, C-terminal domain 382 547 1.5E-30 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CFK41_RS02750 a16a45b9fdc6ecb34dcddf863974672b 827 SUPERFAMILY SSF56300 43 304 6.01E-57 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CFK41_RS02750 a16a45b9fdc6ecb34dcddf863974672b 827 Gene3D G3DSA:3.60.21.10 34 374 3.0E-57 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CFK41_RS02750 a16a45b9fdc6ecb34dcddf863974672b 827 Pfam PF00149 Calcineurin-like phosphoesterase 47 259 6.2E-7 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CFK41_RS06135 74ae541bc07e2bcdb185c386c971e156 487 SMART SM00387 312 415 4.2E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS06135 74ae541bc07e2bcdb185c386c971e156 487 Gene3D G3DSA:1.10.287.130 189 266 3.3E-8 T 28-03-2018 CFK41_RS06135 74ae541bc07e2bcdb185c386c971e156 487 Pfam PF00512 His Kinase A (phospho-acceptor) domain 206 262 7.7E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CFK41_RS06135 74ae541bc07e2bcdb185c386c971e156 487 SUPERFAMILY SSF55874 272 406 2.23E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS06135 74ae541bc07e2bcdb185c386c971e156 487 SMART SM00388 205 270 1.4E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CFK41_RS06135 74ae541bc07e2bcdb185c386c971e156 487 Gene3D G3DSA:3.30.565.10 274 428 1.5E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS06135 74ae541bc07e2bcdb185c386c971e156 487 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 314 401 4.7E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS06135 74ae541bc07e2bcdb185c386c971e156 487 SUPERFAMILY SSF47384 191 266 7.06E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CFK41_RS06135 74ae541bc07e2bcdb185c386c971e156 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 395 4.8E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS06135 74ae541bc07e2bcdb185c386c971e156 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 375 4.8E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS06135 74ae541bc07e2bcdb185c386c971e156 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 347 361 4.8E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS06120 ae430f1e4ca98cc57fdb392eb88317d2 302 Gene3D G3DSA:3.30.930.10 1 208 1.2E-41 T 28-03-2018 CFK41_RS06120 ae430f1e4ca98cc57fdb392eb88317d2 302 Gene3D G3DSA:2.30.30.100 222 280 7.5E-13 T 28-03-2018 CFK41_RS06120 ae430f1e4ca98cc57fdb392eb88317d2 302 Pfam PF03099 Biotin/lipoate A/B protein ligase family 42 141 6.7E-8 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CFK41_RS06120 ae430f1e4ca98cc57fdb392eb88317d2 302 SUPERFAMILY SSF55681 12 196 1.99E-32 T 28-03-2018 CFK41_RS17105 790eae780e3dcb8aff85b43953a312e6 461 Gene3D G3DSA:3.40.50.10840 18 267 2.5E-53 T 28-03-2018 IPR010737 Putative sugar-binding, N-terminal domain CFK41_RS17105 790eae780e3dcb8aff85b43953a312e6 461 Pfam PF07005 Putative sugar-binding N-terminal domain 19 258 5.2E-46 T 28-03-2018 IPR010737 Putative sugar-binding, N-terminal domain CFK41_RS17105 790eae780e3dcb8aff85b43953a312e6 461 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 284 447 3.6E-33 T 28-03-2018 IPR031475 Putative nucleotide-binding C-terminal domain CFK41_RS17105 790eae780e3dcb8aff85b43953a312e6 461 SUPERFAMILY SSF142764 19 454 3.4E-60 T 28-03-2018 CFK41_RS08965 d9967512b65b8457d3fa9442a5439b96 210 TIGRFAM TIGR03085 TIGR03085: TIGR03085 family protein 8 201 3.1E-48 T 28-03-2018 IPR017519 Conserved hypothetical protein CHP03085 CFK41_RS08965 d9967512b65b8457d3fa9442a5439b96 210 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 7 185 1.1E-23 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CFK41_RS08965 d9967512b65b8457d3fa9442a5439b96 210 SUPERFAMILY SSF109854 20 114 3.2E-5 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CFK41_RS08965 d9967512b65b8457d3fa9442a5439b96 210 Gene3D G3DSA:1.20.120.450 6 201 2.1E-6 T 28-03-2018 CFK41_RS11670 03a04e8f9a5ce76b45dbc14150a10690 302 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 15 297 3.6E-74 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CFK41_RS11670 03a04e8f9a5ce76b45dbc14150a10690 302 SUPERFAMILY SSF51569 12 302 6.07E-81 T 28-03-2018 CFK41_RS11670 03a04e8f9a5ce76b45dbc14150a10690 302 PRINTS PR00146 Dihydrodipicolinate synthase signature 114 130 9.1E-26 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS11670 03a04e8f9a5ce76b45dbc14150a10690 302 PRINTS PR00146 Dihydrodipicolinate synthase signature 82 100 9.1E-26 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS11670 03a04e8f9a5ce76b45dbc14150a10690 302 PRINTS PR00146 Dihydrodipicolinate synthase signature 46 67 9.1E-26 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS11670 03a04e8f9a5ce76b45dbc14150a10690 302 PRINTS PR00146 Dihydrodipicolinate synthase signature 139 156 9.1E-26 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS11670 03a04e8f9a5ce76b45dbc14150a10690 302 Pfam PF00701 Dihydrodipicolinate synthetase family 12 298 4.4E-72 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS11670 03a04e8f9a5ce76b45dbc14150a10690 302 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 144 174 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 CFK41_RS11670 03a04e8f9a5ce76b45dbc14150a10690 302 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 11 298 49.825 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CFK41_RS11670 03a04e8f9a5ce76b45dbc14150a10690 302 SMART SM01130 11 300 5.7E-100 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS11670 03a04e8f9a5ce76b45dbc14150a10690 302 PIRSF PIRSF001365 9 302 1.2E-72 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS11670 03a04e8f9a5ce76b45dbc14150a10690 302 Gene3D G3DSA:3.20.20.70 1 302 4.6E-84 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS11475 4bde1f0b2028971a8fd8db43a37d4456 435 SMART SM00864 10 202 2.5E-110 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CFK41_RS11475 4bde1f0b2028971a8fd8db43a37d4456 435 SMART SM00865 204 321 1.1E-54 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CFK41_RS11475 4bde1f0b2028971a8fd8db43a37d4456 435 Gene3D G3DSA:3.40.50.1440 4 211 2.0E-40 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CFK41_RS11475 4bde1f0b2028971a8fd8db43a37d4456 435 ProSitePatterns PS01135 FtsZ protein signature 2. 94 115 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CFK41_RS11475 4bde1f0b2028971a8fd8db43a37d4456 435 SUPERFAMILY SSF52490 9 205 9.55E-68 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CFK41_RS11475 4bde1f0b2028971a8fd8db43a37d4456 435 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 11 170 3.4E-38 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CFK41_RS11475 4bde1f0b2028971a8fd8db43a37d4456 435 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 8 315 3.7E-127 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CFK41_RS11475 4bde1f0b2028971a8fd8db43a37d4456 435 ProSitePatterns PS01134 FtsZ protein signature 1. 41 75 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CFK41_RS11475 4bde1f0b2028971a8fd8db43a37d4456 435 Pfam PF12327 FtsZ family, C-terminal domain 219 313 2.6E-33 T 28-03-2018 IPR024757 Cell division protein FtsZ, C-terminal CFK41_RS11475 4bde1f0b2028971a8fd8db43a37d4456 435 SUPERFAMILY SSF55307 201 314 6.41E-42 T 28-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 CFK41_RS11475 4bde1f0b2028971a8fd8db43a37d4456 435 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 6 355 38.534 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CFK41_RS11475 4bde1f0b2028971a8fd8db43a37d4456 435 Gene3D G3DSA:3.30.1330.20 212 317 4.5E-44 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CFK41_RS11475 4bde1f0b2028971a8fd8db43a37d4456 435 PRINTS PR00423 Cell division protein FtsZ signature 95 115 1.9E-50 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CFK41_RS11475 4bde1f0b2028971a8fd8db43a37d4456 435 PRINTS PR00423 Cell division protein FtsZ signature 123 144 1.9E-50 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CFK41_RS11475 4bde1f0b2028971a8fd8db43a37d4456 435 PRINTS PR00423 Cell division protein FtsZ signature 186 208 1.9E-50 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CFK41_RS11475 4bde1f0b2028971a8fd8db43a37d4456 435 PRINTS PR00423 Cell division protein FtsZ signature 209 230 1.9E-50 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CFK41_RS02160 2e18152e2637f5940be3f334fab426cf 176 Gene3D G3DSA:3.20.80.10 12 169 1.4E-11 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain CFK41_RS02160 2e18152e2637f5940be3f334fab426cf 176 SUPERFAMILY SSF55136 18 155 5.76E-10 T 28-03-2018 CFK41_RS11215 6ca51cea953970c013ee33746153fc34 709 Pfam PF13361 UvrD-like helicase C-terminal domain 297 423 1.5E-21 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CFK41_RS11215 6ca51cea953970c013ee33746153fc34 709 Pfam PF13361 UvrD-like helicase C-terminal domain 489 560 2.0E-22 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CFK41_RS11215 6ca51cea953970c013ee33746153fc34 709 Gene3D G3DSA:3.40.50.300 295 586 4.5E-55 T 28-03-2018 CFK41_RS11215 6ca51cea953970c013ee33746153fc34 709 Gene3D G3DSA:1.10.150.80 616 704 1.6E-21 T 28-03-2018 CFK41_RS11215 6ca51cea953970c013ee33746153fc34 709 SUPERFAMILY SSF52540 19 579 8.46E-120 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11215 6ca51cea953970c013ee33746153fc34 709 SMART SM00341 632 709 1.5E-10 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CFK41_RS11215 6ca51cea953970c013ee33746153fc34 709 Pfam PF00570 HRDC domain 636 701 1.0E-21 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CFK41_RS11215 6ca51cea953970c013ee33746153fc34 709 Pfam PF13245 AAA domain 31 276 9.7E-36 T 28-03-2018 CFK41_RS11215 6ca51cea953970c013ee33746153fc34 709 Gene3D G3DSA:3.40.50.300 19 294 3.3E-49 T 28-03-2018 CFK41_RS11215 6ca51cea953970c013ee33746153fc34 709 SUPERFAMILY SSF47819 627 703 4.58E-18 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 CFK41_RS14505 0a0ef4ff7c3eda72f439722bcd08caf3 451 Pfam PF13416 Bacterial extracellular solute-binding protein 79 384 1.6E-34 T 28-03-2018 CFK41_RS14505 0a0ef4ff7c3eda72f439722bcd08caf3 451 Gene3D G3DSA:3.40.190.10 234 400 3.7E-11 T 28-03-2018 CFK41_RS14505 0a0ef4ff7c3eda72f439722bcd08caf3 451 SUPERFAMILY SSF53850 60 442 1.2E-62 T 28-03-2018 CFK41_RS14505 0a0ef4ff7c3eda72f439722bcd08caf3 451 Gene3D G3DSA:3.40.190.10 64 233 3.7E-28 T 28-03-2018 CFK41_RS11890 e3bb88699e3e4ea21082fedfe8ecd36a 192 Pfam PF00717 Peptidase S24-like 41 116 2.4E-14 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CFK41_RS11890 e3bb88699e3e4ea21082fedfe8ecd36a 192 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 140 159 2.4E-22 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CFK41_RS11890 e3bb88699e3e4ea21082fedfe8ecd36a 192 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 35 51 2.4E-22 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CFK41_RS11890 e3bb88699e3e4ea21082fedfe8ecd36a 192 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 92 104 2.4E-22 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CFK41_RS11890 e3bb88699e3e4ea21082fedfe8ecd36a 192 Gene3D G3DSA:2.10.109.10 31 192 7.4E-40 T 28-03-2018 CFK41_RS11890 e3bb88699e3e4ea21082fedfe8ecd36a 192 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 21 186 1.1E-38 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CFK41_RS11890 e3bb88699e3e4ea21082fedfe8ecd36a 192 ProSitePatterns PS00761 Signal peptidases I signature 3. 145 158 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CFK41_RS11890 e3bb88699e3e4ea21082fedfe8ecd36a 192 SUPERFAMILY SSF51306 33 190 1.22E-43 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CFK41_RS16130 ce7a4c607d271767a19a05d63a17e43a 473 Gene3D G3DSA:3.20.20.80 5 396 5.9E-75 T 28-03-2018 CFK41_RS16130 ce7a4c607d271767a19a05d63a17e43a 473 SUPERFAMILY SSF51445 6 397 1.89E-77 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS16130 ce7a4c607d271767a19a05d63a17e43a 473 SMART SM00642 17 341 1.1E-43 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CFK41_RS16130 ce7a4c607d271767a19a05d63a17e43a 473 Pfam PF00128 Alpha amylase, catalytic domain 57 330 1.0E-37 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CFK41_RS16130 ce7a4c607d271767a19a05d63a17e43a 473 Pfam PF11941 Domain of unknown function (DUF3459) 383 471 4.3E-5 T 28-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) CFK41_RS15455 f770a75000e24359d5b6d5812bc95741 391 SUPERFAMILY SSF53335 2 390 6.55E-46 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS15455 f770a75000e24359d5b6d5812bc95741 391 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 319 390 6.4E-7 T 28-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CFK41_RS15455 f770a75000e24359d5b6d5812bc95741 391 Gene3D G3DSA:3.40.50.150 1 389 2.4E-39 T 28-03-2018 CFK41_RS15455 f770a75000e24359d5b6d5812bc95741 391 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 323 354 - T 28-03-2018 IPR030390 RNA methyltransferase TrmA, active site CFK41_RS15455 f770a75000e24359d5b6d5812bc95741 391 Pfam PF13649 Methyltransferase domain 247 306 6.9E-7 T 28-03-2018 CFK41_RS13555 b11c92fb3921a739d83ff827e5f5968a 325 SUPERFAMILY SSF53254 136 285 3.67E-32 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CFK41_RS13555 b11c92fb3921a739d83ff827e5f5968a 325 ProSitePatterns PS00893 Nudix box signature. 36 57 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CFK41_RS13555 b11c92fb3921a739d83ff827e5f5968a 325 PRINTS PR00502 NUDIX hydrolase family signature 31 45 5.0E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CFK41_RS13555 b11c92fb3921a739d83ff827e5f5968a 325 PRINTS PR00502 NUDIX hydrolase family signature 45 60 5.0E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CFK41_RS13555 b11c92fb3921a739d83ff827e5f5968a 325 Pfam PF00293 NUDIX domain 5 115 2.0E-14 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CFK41_RS13555 b11c92fb3921a739d83ff827e5f5968a 325 Gene3D G3DSA:3.90.79.10 2 129 2.3E-18 T 28-03-2018 CFK41_RS13555 b11c92fb3921a739d83ff827e5f5968a 325 SMART SM00855 137 281 3.8E-10 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CFK41_RS13555 b11c92fb3921a739d83ff827e5f5968a 325 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 138 285 7.8E-34 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CFK41_RS13555 b11c92fb3921a739d83ff827e5f5968a 325 Gene3D G3DSA:3.40.50.1240 130 323 9.3E-32 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CFK41_RS13555 b11c92fb3921a739d83ff827e5f5968a 325 SUPERFAMILY SSF55811 5 123 2.57E-19 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CFK41_RS13555 b11c92fb3921a739d83ff827e5f5968a 325 PIRSF PIRSF000709 233 282 10.0 T 28-03-2018 CFK41_RS13555 b11c92fb3921a739d83ff827e5f5968a 325 PIRSF PIRSF000709 128 215 0.0013 T 28-03-2018 CFK41_RS00760 68f8ad4cd3b00df3ddd748d251311068 287 SUPERFAMILY SSF103481 191 286 2.48E-13 T 28-03-2018 CFK41_RS00760 68f8ad4cd3b00df3ddd748d251311068 287 SUPERFAMILY SSF103481 43 141 3.92E-11 T 28-03-2018 CFK41_RS00760 68f8ad4cd3b00df3ddd748d251311068 287 Pfam PF00892 EamA-like transporter family 5 137 2.6E-7 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CFK41_RS00760 68f8ad4cd3b00df3ddd748d251311068 287 Pfam PF00892 EamA-like transporter family 150 286 2.3E-9 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CFK41_RS06245 412987f0c561e66bdb68e5d8fb23f40a 256 Gene3D G3DSA:3.40.50.300 17 255 6.1E-48 T 28-03-2018 CFK41_RS06245 412987f0c561e66bdb68e5d8fb23f40a 256 Pfam PF00005 ABC transporter 58 189 3.2E-16 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS06245 412987f0c561e66bdb68e5d8fb23f40a 256 SUPERFAMILY SSF52540 38 250 4.13E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS06245 412987f0c561e66bdb68e5d8fb23f40a 256 SMART SM00382 67 238 3.5E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS06025 c8c668868a65c036ad2a778f5fac536e 523 Gene3D G3DSA:3.40.50.300 1 230 5.2E-51 T 28-03-2018 CFK41_RS06025 c8c668868a65c036ad2a778f5fac536e 523 ProSitePatterns PS00211 ABC transporters family signature. 399 413 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS06025 c8c668868a65c036ad2a778f5fac536e 523 Gene3D G3DSA:3.40.50.300 250 514 6.3E-34 T 28-03-2018 CFK41_RS06025 c8c668868a65c036ad2a778f5fac536e 523 SMART SM00382 27 215 2.6E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS06025 c8c668868a65c036ad2a778f5fac536e 523 SMART SM00382 279 475 7.0 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS06025 c8c668868a65c036ad2a778f5fac536e 523 Pfam PF00005 ABC transporter 20 167 2.6E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS06025 c8c668868a65c036ad2a778f5fac536e 523 Pfam PF00005 ABC transporter 270 426 4.0E-16 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS06025 c8c668868a65c036ad2a778f5fac536e 523 SUPERFAMILY SSF52540 3 223 2.44E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS06025 c8c668868a65c036ad2a778f5fac536e 523 SUPERFAMILY SSF52540 253 484 7.94E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS10245 549173cc6a9a96dd31d8a6c522cfe6d9 635 Pfam PF16326 ABC transporter C-terminal domain 571 632 1.2E-12 T 28-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CFK41_RS10245 549173cc6a9a96dd31d8a6c522cfe6d9 635 SUPERFAMILY SSF52540 278 487 9.28E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS10245 549173cc6a9a96dd31d8a6c522cfe6d9 635 ProSitePatterns PS00211 ABC transporters family signature. 410 424 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS10245 549173cc6a9a96dd31d8a6c522cfe6d9 635 Pfam PF00005 ABC transporter 20 151 9.2E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS10245 549173cc6a9a96dd31d8a6c522cfe6d9 635 Pfam PF00005 ABC transporter 302 438 8.6E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS10245 549173cc6a9a96dd31d8a6c522cfe6d9 635 Gene3D G3DSA:3.40.50.300 3 268 1.6E-46 T 28-03-2018 CFK41_RS10245 549173cc6a9a96dd31d8a6c522cfe6d9 635 Gene3D G3DSA:1.20.5.1070 566 634 1.0E-4 T 28-03-2018 CFK41_RS10245 549173cc6a9a96dd31d8a6c522cfe6d9 635 SMART SM00382 311 490 1.2E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS10245 549173cc6a9a96dd31d8a6c522cfe6d9 635 SMART SM00382 29 207 2.2E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS10245 549173cc6a9a96dd31d8a6c522cfe6d9 635 SUPERFAMILY SSF52540 6 204 1.48E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS10245 549173cc6a9a96dd31d8a6c522cfe6d9 635 Gene3D G3DSA:3.40.50.300 269 510 1.4E-42 T 28-03-2018 CFK41_RS12145 8ccbb4af4d2716aeff8d32577b66ab4b 227 Gene3D G3DSA:3.90.226.10 24 219 4.3E-42 T 28-03-2018 CFK41_RS12145 8ccbb4af4d2716aeff8d32577b66ab4b 227 PRINTS PR00127 Clp protease catalytic subunit P signature 112 129 1.9E-42 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CFK41_RS12145 8ccbb4af4d2716aeff8d32577b66ab4b 227 PRINTS PR00127 Clp protease catalytic subunit P signature 81 101 1.9E-42 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CFK41_RS12145 8ccbb4af4d2716aeff8d32577b66ab4b 227 PRINTS PR00127 Clp protease catalytic subunit P signature 193 212 1.9E-42 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CFK41_RS12145 8ccbb4af4d2716aeff8d32577b66ab4b 227 PRINTS PR00127 Clp protease catalytic subunit P signature 133 152 1.9E-42 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CFK41_RS12145 8ccbb4af4d2716aeff8d32577b66ab4b 227 PRINTS PR00127 Clp protease catalytic subunit P signature 41 56 1.9E-42 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CFK41_RS12145 8ccbb4af4d2716aeff8d32577b66ab4b 227 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 25 218 39.822 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CFK41_RS12145 8ccbb4af4d2716aeff8d32577b66ab4b 227 Pfam PF00574 Clp protease 38 217 3.5E-74 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CFK41_RS12145 8ccbb4af4d2716aeff8d32577b66ab4b 227 SUPERFAMILY SSF52096 33 220 1.14E-63 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CFK41_RS12145 8ccbb4af4d2716aeff8d32577b66ab4b 227 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 134 147 - T 28-03-2018 IPR033135 ClpP, histidine active site CFK41_RS12145 8ccbb4af4d2716aeff8d32577b66ab4b 227 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 112 123 - T 28-03-2018 IPR018215 ClpP, Ser active site CFK41_RS09570 02394d88caa2db0402184bc601156d5f 371 SUPERFAMILY SSF52283 305 359 1.79E-63 T 28-03-2018 CFK41_RS09570 02394d88caa2db0402184bc601156d5f 371 SUPERFAMILY SSF52283 1 137 1.79E-63 T 28-03-2018 CFK41_RS09570 02394d88caa2db0402184bc601156d5f 371 Gene3D G3DSA:3.40.50.720 1 223 4.4E-49 T 28-03-2018 CFK41_RS09570 02394d88caa2db0402184bc601156d5f 371 PIRSF PIRSF000183 1 371 5.4E-159 T 28-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CFK41_RS09570 02394d88caa2db0402184bc601156d5f 371 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 1.0E-75 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CFK41_RS09570 02394d88caa2db0402184bc601156d5f 371 SMART SM01003 4 137 3.7E-77 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CFK41_RS09570 02394d88caa2db0402184bc601156d5f 371 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 3.4E-45 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CFK41_RS09570 02394d88caa2db0402184bc601156d5f 371 SUPERFAMILY SSF51735 137 303 1.94E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS09570 02394d88caa2db0402184bc601156d5f 371 SMART SM01002 149 297 1.6E-72 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CFK41_RS09570 02394d88caa2db0402184bc601156d5f 371 Gene3D G3DSA:3.40.50.720 224 371 2.8E-39 T 28-03-2018 CFK41_RS09570 02394d88caa2db0402184bc601156d5f 371 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 370 9.6E-161 T 28-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CFK41_RS13610 aa59c99bca16da2cff9949f703c73222 316 Pfam PF07859 alpha/beta hydrolase fold 74 286 2.5E-64 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CFK41_RS13610 aa59c99bca16da2cff9949f703c73222 316 Gene3D G3DSA:3.40.50.1820 12 309 7.3E-55 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS13610 aa59c99bca16da2cff9949f703c73222 316 SUPERFAMILY SSF53474 30 307 3.27E-65 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS06895 d14a494c15dc04fcb55fe3a9d486deab 234 SUPERFAMILY SSF88659 139 201 1.36E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS06895 d14a494c15dc04fcb55fe3a9d486deab 234 Gene3D G3DSA:1.10.1740.10 29 101 8.5E-23 T 28-03-2018 CFK41_RS06895 d14a494c15dc04fcb55fe3a9d486deab 234 Pfam PF04542 Sigma-70 region 2 40 104 2.4E-18 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS06895 d14a494c15dc04fcb55fe3a9d486deab 234 SUPERFAMILY SSF88946 34 119 5.3E-24 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS06895 d14a494c15dc04fcb55fe3a9d486deab 234 Gene3D G3DSA:1.10.10.10 102 203 2.6E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS06895 d14a494c15dc04fcb55fe3a9d486deab 234 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 39 200 2.0E-26 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS06895 d14a494c15dc04fcb55fe3a9d486deab 234 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 59 90 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS06895 d14a494c15dc04fcb55fe3a9d486deab 234 TIGRFAM TIGR02947 SigH_actino: RNA polymerase sigma-70 factor, TIGR02947 family 33 211 4.4E-88 T 28-03-2018 IPR014293 RNA polymerase sigma-70, actinobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS06895 d14a494c15dc04fcb55fe3a9d486deab 234 Pfam PF08281 Sigma-70, region 4 145 196 3.4E-16 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS04670 be6fe41dc79d4770c853e602f5d64670 228 SUPERFAMILY SSF54768 50 117 8.79E-23 T 28-03-2018 CFK41_RS04670 be6fe41dc79d4770c853e602f5d64670 228 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 204 34.696 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CFK41_RS04670 be6fe41dc79d4770c853e602f5d64670 228 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 50 203 8.2E-68 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CFK41_RS04670 be6fe41dc79d4770c853e602f5d64670 228 Gene3D G3DSA:3.30.230.10 118 207 1.3E-29 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CFK41_RS04670 be6fe41dc79d4770c853e602f5d64670 228 ProSitePatterns PS00585 Ribosomal protein S5 signature. 69 101 - T 28-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site CFK41_RS04670 be6fe41dc79d4770c853e602f5d64670 228 Gene3D G3DSA:3.30.160.20 51 112 2.0E-26 T 28-03-2018 CFK41_RS04670 be6fe41dc79d4770c853e602f5d64670 228 Pfam PF03719 Ribosomal protein S5, C-terminal domain 128 198 4.1E-29 T 28-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 CFK41_RS04670 be6fe41dc79d4770c853e602f5d64670 228 Pfam PF00333 Ribosomal protein S5, N-terminal domain 53 116 2.6E-28 T 28-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 CFK41_RS04670 be6fe41dc79d4770c853e602f5d64670 228 SUPERFAMILY SSF54211 120 199 1.67E-24 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CFK41_RS12260 745c23434502eebe4e11033e36f9b306 121 Pfam PF14019 Protein of unknown function (DUF4235) 6 113 2.0E-26 T 28-03-2018 IPR025329 Protein of unknown function DUF4235 CFK41_RS03765 aba312886992e506eee7bdd4d7ee5b0e 235 SUPERFAMILY SSF56784 27 224 8.27E-40 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS03765 aba312886992e506eee7bdd4d7ee5b0e 235 Pfam PF13419 Haloacid dehalogenase-like hydrolase 30 206 6.3E-24 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS03765 aba312886992e506eee7bdd4d7ee5b0e 235 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 145 205 1.1E-11 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CFK41_RS03765 aba312886992e506eee7bdd4d7ee5b0e 235 Gene3D G3DSA:1.10.150.240 40 99 1.1E-7 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CFK41_RS03765 aba312886992e506eee7bdd4d7ee5b0e 235 Gene3D G3DSA:3.40.50.1000 100 230 1.4E-23 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS07560 521f62fdf8fe30d5f40887b8c4325883 125 Pfam PF02410 Ribosomal silencing factor during starvation 17 109 1.7E-21 T 28-03-2018 CFK41_RS07560 521f62fdf8fe30d5f40887b8c4325883 125 SUPERFAMILY SSF81301 7 119 1.44E-35 T 28-03-2018 CFK41_RS07560 521f62fdf8fe30d5f40887b8c4325883 125 Gene3D G3DSA:3.30.460.10 5 125 1.4E-28 T 28-03-2018 CFK41_RS07560 521f62fdf8fe30d5f40887b8c4325883 125 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 13 109 3.2E-30 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CFK41_RS07560 521f62fdf8fe30d5f40887b8c4325883 125 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 7 110 22.609 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CFK41_RS15050 728652bff739dfc8d3f53e0c66130259 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 55 1.1E-18 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS15050 728652bff739dfc8d3f53e0c66130259 55 SUPERFAMILY SSF57829 4 55 2.32E-15 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CFK41_RS15050 728652bff739dfc8d3f53e0c66130259 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 7 55 12.694 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS15050 728652bff739dfc8d3f53e0c66130259 55 Pfam PF00471 Ribosomal protein L33 10 54 5.2E-14 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS15050 728652bff739dfc8d3f53e0c66130259 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 23 42 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS00060 5371a9357cbeafdedbf1667ff492048e 463 Pfam PF01969 Protein of unknown function DUF111 249 445 3.3E-54 T 28-03-2018 IPR035108 LarC/UPF0272 CFK41_RS00060 5371a9357cbeafdedbf1667ff492048e 463 Pfam PF01969 Protein of unknown function DUF111 10 199 1.9E-54 T 28-03-2018 IPR035108 LarC/UPF0272 CFK41_RS00060 5371a9357cbeafdedbf1667ff492048e 463 Hamap MF_01074 UPF0272 protein . 6 457 33.03 T 28-03-2018 IPR002822 Uncharacterised protein family UPF0272 CFK41_RS00060 5371a9357cbeafdedbf1667ff492048e 463 Gene3D G3DSA:3.30.70.1380 325 394 1.4E-25 T 28-03-2018 CFK41_RS00060 5371a9357cbeafdedbf1667ff492048e 463 Gene3D G3DSA:3.40.50.1980 101 324 6.9E-5 T 28-03-2018 CFK41_RS00060 5371a9357cbeafdedbf1667ff492048e 463 Gene3D G3DSA:3.10.20.300 395 459 6.8E-9 T 28-03-2018 CFK41_RS11470 407452ea9dea8cd4edc5561a01c22e1e 244 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 33 242 5.5E-48 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase CFK41_RS11470 407452ea9dea8cd4edc5561a01c22e1e 244 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 20 241 1.8E-72 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase CFK41_RS11470 407452ea9dea8cd4edc5561a01c22e1e 244 Gene3D G3DSA:3.60.140.10 2 244 3.7E-85 T 28-03-2018 CFK41_RS11470 407452ea9dea8cd4edc5561a01c22e1e 244 SUPERFAMILY SSF64438 10 243 3.3E-71 T 28-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic CFK41_RS07625 d8e8cb3ba99c90a2ba6c07100accabee 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 9.4E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CFK41_RS07625 d8e8cb3ba99c90a2ba6c07100accabee 299 Gene3D G3DSA:3.40.190.10 93 181 6.0E-25 T 28-03-2018 CFK41_RS07625 d8e8cb3ba99c90a2ba6c07100accabee 299 SUPERFAMILY SSF53850 92 294 4.44E-37 T 28-03-2018 CFK41_RS07625 d8e8cb3ba99c90a2ba6c07100accabee 299 Gene3D G3DSA:3.40.190.10 182 272 7.4E-19 T 28-03-2018 CFK41_RS07625 d8e8cb3ba99c90a2ba6c07100accabee 299 Gene3D G3DSA:1.10.10.10 6 87 8.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS07625 d8e8cb3ba99c90a2ba6c07100accabee 299 Pfam PF03466 LysR substrate binding domain 92 292 4.5E-40 T 28-03-2018 IPR005119 LysR, substrate-binding CFK41_RS07625 d8e8cb3ba99c90a2ba6c07100accabee 299 SUPERFAMILY SSF46785 5 116 5.55E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS17110 065ce75831b3b8be38baf2c54313a7f1 466 Pfam PF02447 GntP family permease 14 460 5.6E-109 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CFK41_RS17110 065ce75831b3b8be38baf2c54313a7f1 466 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 16 464 9.5E-103 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CFK41_RS17110 065ce75831b3b8be38baf2c54313a7f1 466 PIRSF PIRSF002746 10 466 2.8E-130 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CFK41_RS13990 d7a48dbf5c81c69c9708857ec96682eb 411 Gene3D G3DSA:1.20.1250.20 10 196 1.9E-8 T 28-03-2018 CFK41_RS13990 d7a48dbf5c81c69c9708857ec96682eb 411 SUPERFAMILY SSF103473 11 390 5.62E-26 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS13990 d7a48dbf5c81c69c9708857ec96682eb 411 Gene3D G3DSA:1.20.1250.20 197 403 1.1E-10 T 28-03-2018 CFK41_RS09435 6917dd7240755951336d9c4c91fd87d4 492 SUPERFAMILY SSF51971 146 407 6.47E-61 T 28-03-2018 CFK41_RS09435 6917dd7240755951336d9c4c91fd87d4 492 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 389 462 9.4E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS09435 6917dd7240755951336d9c4c91fd87d4 492 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 149 322 1.1E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS09435 6917dd7240755951336d9c4c91fd87d4 492 SUPERFAMILY SSF51971 374 476 6.12E-13 T 28-03-2018 CFK41_RS09435 6917dd7240755951336d9c4c91fd87d4 492 Gene3D G3DSA:1.10.1060.10 7 144 2.0E-37 T 28-03-2018 CFK41_RS09435 6917dd7240755951336d9c4c91fd87d4 492 PRINTS PR00419 Adrenodoxin reductase family signature 149 171 3.5E-19 T 28-03-2018 CFK41_RS09435 6917dd7240755951336d9c4c91fd87d4 492 PRINTS PR00419 Adrenodoxin reductase family signature 292 306 3.5E-19 T 28-03-2018 CFK41_RS09435 6917dd7240755951336d9c4c91fd87d4 492 PRINTS PR00419 Adrenodoxin reductase family signature 172 185 3.5E-19 T 28-03-2018 CFK41_RS09435 6917dd7240755951336d9c4c91fd87d4 492 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 480 4.3E-196 T 28-03-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 CFK41_RS09435 6917dd7240755951336d9c4c91fd87d4 492 SUPERFAMILY SSF46548 12 158 1.52E-33 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CFK41_RS09435 6917dd7240755951336d9c4c91fd87d4 492 Gene3D G3DSA:3.50.50.60 249 338 4.0E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS09435 6917dd7240755951336d9c4c91fd87d4 492 Gene3D G3DSA:3.50.50.60 339 407 1.3E-4 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS09435 6917dd7240755951336d9c4c91fd87d4 492 Gene3D G3DSA:3.40.50.720 145 248 1.6E-21 T 28-03-2018 CFK41_RS09435 6917dd7240755951336d9c4c91fd87d4 492 Gene3D G3DSA:3.50.50.60 411 486 1.5E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS09435 6917dd7240755951336d9c4c91fd87d4 492 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 36 134 2.7E-21 T 28-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 CFK41_RS06705 659211656f746fec8520b716e97488ab 239 Pfam PF00106 short chain dehydrogenase 8 187 4.3E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS06705 659211656f746fec8520b716e97488ab 239 Gene3D G3DSA:3.40.50.720 1 224 1.1E-47 T 28-03-2018 CFK41_RS06705 659211656f746fec8520b716e97488ab 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 9.3E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS06705 659211656f746fec8520b716e97488ab 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 9.3E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS06705 659211656f746fec8520b716e97488ab 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 9.3E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS06705 659211656f746fec8520b716e97488ab 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 9.3E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS06705 659211656f746fec8520b716e97488ab 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 9.3E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS06705 659211656f746fec8520b716e97488ab 239 SUPERFAMILY SSF51735 1 186 4.35E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS06705 659211656f746fec8520b716e97488ab 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 162 1.5E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS06705 659211656f746fec8520b716e97488ab 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 70 81 1.5E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS06705 659211656f746fec8520b716e97488ab 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 1.5E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS10105 9827acd351ae51a00536e7d7794538f9 391 Pfam PF12555 Thiamine pyrophosphokinase C terminal 326 376 1.0E-16 T 28-03-2018 IPR022215 Thiamine pyrophosphokinase C-terminal CFK41_RS10105 9827acd351ae51a00536e7d7794538f9 391 SUPERFAMILY SSF63999 148 328 8.37E-27 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CFK41_RS10105 9827acd351ae51a00536e7d7794538f9 391 Gene3D G3DSA:3.40.50.10240 166 247 5.0E-10 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CFK41_RS06550 6edd4c752f5f0ec80bdef0db22d5ef0b 382 Pfam PF07075 Protein of unknown function (DUF1343) 26 373 2.2E-88 T 28-03-2018 IPR008302 Uncharacterised conserved protein UCP016719 CFK41_RS06550 6edd4c752f5f0ec80bdef0db22d5ef0b 382 PIRSF PIRSF016719 2 377 1.1E-87 T 28-03-2018 IPR008302 Uncharacterised conserved protein UCP016719 CFK41_RS06550 6edd4c752f5f0ec80bdef0db22d5ef0b 382 Gene3D G3DSA:3.50.50.60 65 345 0.0016 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS03945 381a91fb6054494d42100c0b77fdae73 81 Pfam PF00462 Glutaredoxin 1 57 3.5E-13 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CFK41_RS03945 381a91fb6054494d42100c0b77fdae73 81 TIGRFAM TIGR02194 GlrX_NrdH: glutaredoxin-like protein NrdH 1 69 2.7E-29 T 28-03-2018 IPR011909 Glutaredoxin-like protein NrdH GO:0045454 CFK41_RS03945 381a91fb6054494d42100c0b77fdae73 81 Gene3D G3DSA:3.40.30.10 1 80 5.8E-13 T 28-03-2018 CFK41_RS03945 381a91fb6054494d42100c0b77fdae73 81 SUPERFAMILY SSF52833 1 69 8.67E-16 T 28-03-2018 IPR012336 Thioredoxin-like fold CFK41_RS02205 7514c2d3f83cb67e0c82baf528639bbc 280 SUPERFAMILY SSF47413 31 82 5.63E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS02205 7514c2d3f83cb67e0c82baf528639bbc 280 SMART SM00530 11 83 8.3E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CFK41_RS02205 7514c2d3f83cb67e0c82baf528639bbc 280 Pfam PF13560 Helix-turn-helix domain 8 86 2.6E-15 T 28-03-2018 CFK41_RS02205 7514c2d3f83cb67e0c82baf528639bbc 280 Gene3D G3DSA:1.10.260.40 3 83 1.1E-12 T 28-03-2018 CFK41_RS05520 c4d46158fc8c8945d59232b628794f8e 173 SUPERFAMILY SSF53271 8 161 3.67E-29 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CFK41_RS05520 c4d46158fc8c8945d59232b628794f8e 173 Pfam PF00156 Phosphoribosyl transferase domain 15 161 7.9E-25 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CFK41_RS05520 c4d46158fc8c8945d59232b628794f8e 173 Gene3D G3DSA:3.40.50.2020 12 170 6.6E-27 T 28-03-2018 CFK41_RS06150 f0cc2767dceafd6879450b32f07b5c54 286 Pfam PF00005 ABC transporter 76 206 1.3E-16 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS06150 f0cc2767dceafd6879450b32f07b5c54 286 ProSitePatterns PS00211 ABC transporters family signature. 179 193 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS06150 f0cc2767dceafd6879450b32f07b5c54 286 SMART SM00382 84 261 4.3E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS06150 f0cc2767dceafd6879450b32f07b5c54 286 Gene3D G3DSA:3.40.50.300 25 283 1.3E-41 T 28-03-2018 CFK41_RS06150 f0cc2767dceafd6879450b32f07b5c54 286 SUPERFAMILY SSF52540 70 268 7.17E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS01845 83f145c53ae89931cfe37c6304b63f0a 559 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 84 114 8.2E-6 T 28-03-2018 IPR001451 Hexapeptide repeat CFK41_RS01845 83f145c53ae89931cfe37c6304b63f0a 559 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 137 171 1.8E-6 T 28-03-2018 IPR001451 Hexapeptide repeat CFK41_RS01845 83f145c53ae89931cfe37c6304b63f0a 559 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 145 173 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CFK41_RS01845 83f145c53ae89931cfe37c6304b63f0a 559 SUPERFAMILY SSF51161 42 193 3.6E-38 T 28-03-2018 IPR011004 Trimeric LpxA-like CFK41_RS01845 83f145c53ae89931cfe37c6304b63f0a 559 Gene3D G3DSA:2.160.10.10 30 189 1.8E-37 T 28-03-2018 CFK41_RS05080 331c2c570648008501c371dd2f32dfcc 93 Gene3D G3DSA:3.30.2310.20 1 93 5.4E-26 T 28-03-2018 CFK41_RS05080 331c2c570648008501c371dd2f32dfcc 93 Pfam PF05015 RelE-like toxin of type II toxin-antitoxin system HigB 4 93 7.2E-16 T 28-03-2018 IPR007711 Toxin HigB-1 CFK41_RS05080 331c2c570648008501c371dd2f32dfcc 93 SUPERFAMILY SSF143011 4 93 3.34E-13 T 28-03-2018 IPR035095 Toxin RelE-like domain CFK41_RS05015 357a00b9b1987dd8c4246610a51075e1 498 Pfam PF00939 Sodium:sulfate symporter transmembrane region 58 488 1.4E-28 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 CFK41_RS08535 dff14996979b26a1d5b3a50e7fc2dcfd 492 PRINTS PR00481 Cytosol aminopeptidase signature 361 376 1.2E-49 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CFK41_RS08535 dff14996979b26a1d5b3a50e7fc2dcfd 492 PRINTS PR00481 Cytosol aminopeptidase signature 274 295 1.2E-49 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CFK41_RS08535 dff14996979b26a1d5b3a50e7fc2dcfd 492 PRINTS PR00481 Cytosol aminopeptidase signature 311 332 1.2E-49 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CFK41_RS08535 dff14996979b26a1d5b3a50e7fc2dcfd 492 PRINTS PR00481 Cytosol aminopeptidase signature 333 353 1.2E-49 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CFK41_RS08535 dff14996979b26a1d5b3a50e7fc2dcfd 492 PRINTS PR00481 Cytosol aminopeptidase signature 252 269 1.2E-49 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CFK41_RS08535 dff14996979b26a1d5b3a50e7fc2dcfd 492 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 337 344 - T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CFK41_RS08535 dff14996979b26a1d5b3a50e7fc2dcfd 492 Gene3D G3DSA:3.40.220.10 1 154 3.9E-23 T 28-03-2018 CFK41_RS08535 dff14996979b26a1d5b3a50e7fc2dcfd 492 SUPERFAMILY SSF52949 17 140 3.59E-15 T 28-03-2018 CFK41_RS08535 dff14996979b26a1d5b3a50e7fc2dcfd 492 Gene3D G3DSA:3.40.630.10 161 490 1.3E-128 T 28-03-2018 CFK41_RS08535 dff14996979b26a1d5b3a50e7fc2dcfd 492 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 39 136 1.8E-14 T 28-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CFK41_RS08535 dff14996979b26a1d5b3a50e7fc2dcfd 492 SUPERFAMILY SSF53187 172 486 2.3E-109 T 28-03-2018 CFK41_RS08535 dff14996979b26a1d5b3a50e7fc2dcfd 492 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 4 488 32.002 T 28-03-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 CFK41_RS08535 dff14996979b26a1d5b3a50e7fc2dcfd 492 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 177 479 3.3E-114 T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CFK41_RS05515 6fdee5cfec5b89fd9f94e80a5d9f2285 366 SUPERFAMILY SSF53850 66 285 4.67E-25 T 28-03-2018 CFK41_RS05515 6fdee5cfec5b89fd9f94e80a5d9f2285 366 Gene3D G3DSA:3.40.190.10 203 287 0.0069 T 28-03-2018 CFK41_RS05515 6fdee5cfec5b89fd9f94e80a5d9f2285 366 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 90 285 2.0E-13 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CFK41_RS05515 6fdee5cfec5b89fd9f94e80a5d9f2285 366 Gene3D G3DSA:3.40.190.10 58 202 4.4E-12 T 28-03-2018 CFK41_RS08305 dbd36ecd2821588c9e5f617641dea502 227 Pfam PF09335 SNARE associated Golgi protein 34 157 6.0E-15 T 28-03-2018 IPR032816 SNARE associated Golgi protein CFK41_RS12345 79e1b4799c20bef7f147074c0fc5c0a3 287 PIRSF PIRSF018249 11 287 9.9E-80 T 28-03-2018 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 CFK41_RS12345 79e1b4799c20bef7f147074c0fc5c0a3 287 Gene3D G3DSA:3.40.50.150 15 287 3.4E-38 T 28-03-2018 CFK41_RS12345 79e1b4799c20bef7f147074c0fc5c0a3 287 Pfam PF13649 Methyltransferase domain 103 186 1.2E-7 T 28-03-2018 CFK41_RS12345 79e1b4799c20bef7f147074c0fc5c0a3 287 SUPERFAMILY SSF53335 18 221 9.29E-30 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS01210 ec737480009ec5f4ff12c074b8604194 163 ProSitePatterns PS00893 Nudix box signature. 48 69 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CFK41_RS01210 ec737480009ec5f4ff12c074b8604194 163 PRINTS PR00502 NUDIX hydrolase family signature 57 72 7.4E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CFK41_RS01210 ec737480009ec5f4ff12c074b8604194 163 PRINTS PR00502 NUDIX hydrolase family signature 43 57 7.4E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CFK41_RS01210 ec737480009ec5f4ff12c074b8604194 163 Gene3D G3DSA:3.90.79.10 12 158 7.7E-21 T 28-03-2018 CFK41_RS01210 ec737480009ec5f4ff12c074b8604194 163 SUPERFAMILY SSF55811 15 140 1.04E-21 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CFK41_RS01210 ec737480009ec5f4ff12c074b8604194 163 Pfam PF00293 NUDIX domain 20 143 4.0E-16 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CFK41_RS08920 bed93aafb5184acb71e633a92764bfc5 397 SUPERFAMILY SSF103473 2 382 1.02E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS08920 bed93aafb5184acb71e633a92764bfc5 397 Gene3D G3DSA:1.20.1250.20 1 187 5.7E-30 T 28-03-2018 CFK41_RS08920 bed93aafb5184acb71e633a92764bfc5 397 Gene3D G3DSA:1.20.1250.20 190 384 7.3E-19 T 28-03-2018 CFK41_RS08920 bed93aafb5184acb71e633a92764bfc5 397 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 2 379 5.7E-74 T 28-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 CFK41_RS08920 bed93aafb5184acb71e633a92764bfc5 397 ProSitePatterns PS00216 Sugar transport proteins signature 1. 56 72 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CFK41_RS08920 bed93aafb5184acb71e633a92764bfc5 397 Pfam PF07690 Major Facilitator Superfamily 10 350 9.7E-47 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS11715 963e6d72570a6856df58b71928d73d7e 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 1 89 22.217 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS11715 963e6d72570a6856df58b71928d73d7e 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 6.3E-39 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS11715 963e6d72570a6856df58b71928d73d7e 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 5.0E-30 T 28-03-2018 CFK41_RS11715 963e6d72570a6856df58b71928d73d7e 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS11715 963e6d72570a6856df58b71928d73d7e 89 Pfam PF00312 Ribosomal protein S15 8 88 3.7E-38 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS11715 963e6d72570a6856df58b71928d73d7e 89 Gene3D G3DSA:1.10.287.10 2 89 2.7E-35 T 28-03-2018 CFK41_RS11715 963e6d72570a6856df58b71928d73d7e 89 SMART SM01387 8 88 4.8E-54 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS11715 963e6d72570a6856df58b71928d73d7e 89 SUPERFAMILY SSF47060 5 89 3.83E-36 T 28-03-2018 IPR009068 S15/NS1, RNA-binding CFK41_RS09215 7a4479f3a2d9d5a341625afad300813e 258 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 9 248 3.7E-53 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS09215 7a4479f3a2d9d5a341625afad300813e 258 SUPERFAMILY SSF51351 4 255 1.96E-87 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS09215 7a4479f3a2d9d5a341625afad300813e 258 ProSitePatterns PS00171 Triosephosphate isomerase active site. 172 182 - T 28-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS09215 7a4479f3a2d9d5a341625afad300813e 258 Gene3D G3DSA:3.20.20.70 3 256 5.9E-97 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS09215 7a4479f3a2d9d5a341625afad300813e 258 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 5 257 38.511 T 28-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS09215 7a4479f3a2d9d5a341625afad300813e 258 Pfam PF00121 Triosephosphate isomerase 8 253 4.2E-85 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS11090 e45e2b0fd9c23608f4465d5abf41b248 587 ProSitePatterns PS00211 ABC transporters family signature. 489 503 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS11090 e45e2b0fd9c23608f4465d5abf41b248 587 SUPERFAMILY SSF90123 17 323 2.62E-46 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS11090 e45e2b0fd9c23608f4465d5abf41b248 587 Pfam PF00664 ABC transporter transmembrane region 36 300 9.7E-20 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS11090 e45e2b0fd9c23608f4465d5abf41b248 587 Pfam PF00005 ABC transporter 428 516 2.1E-8 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS11090 e45e2b0fd9c23608f4465d5abf41b248 587 SUPERFAMILY SSF52540 406 580 1.52E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11090 e45e2b0fd9c23608f4465d5abf41b248 587 Gene3D G3DSA:1.20.1560.10 12 335 4.9E-35 T 28-03-2018 CFK41_RS11090 e45e2b0fd9c23608f4465d5abf41b248 587 Gene3D G3DSA:3.40.50.300 336 585 5.4E-34 T 28-03-2018 CFK41_RS14035 3bd36d70730b408649b1588174c8e382 227 SMART SM00421 165 222 3.0E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS14035 3bd36d70730b408649b1588174c8e382 227 Gene3D G3DSA:3.40.50.2300 11 134 1.1E-34 T 28-03-2018 CFK41_RS14035 3bd36d70730b408649b1588174c8e382 227 ProSitePatterns PS00622 LuxR-type HTH domain signature. 182 209 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS14035 3bd36d70730b408649b1588174c8e382 227 Pfam PF00196 Bacterial regulatory proteins, luxR family 168 220 1.5E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS14035 3bd36d70730b408649b1588174c8e382 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 198 210 1.7E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS14035 3bd36d70730b408649b1588174c8e382 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 182 1.7E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS14035 3bd36d70730b408649b1588174c8e382 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 198 1.7E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS14035 3bd36d70730b408649b1588174c8e382 227 SUPERFAMILY SSF46894 161 225 1.43E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CFK41_RS14035 3bd36d70730b408649b1588174c8e382 227 SMART SM00448 12 123 3.1E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS14035 3bd36d70730b408649b1588174c8e382 227 Gene3D G3DSA:1.10.10.10 135 226 8.9E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS14035 3bd36d70730b408649b1588174c8e382 227 Pfam PF00072 Response regulator receiver domain 14 124 1.1E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS14035 3bd36d70730b408649b1588174c8e382 227 SUPERFAMILY SSF52172 11 135 1.2E-31 T 28-03-2018 IPR011006 CheY-like superfamily CFK41_RS04940 1c9558889f90aafd1ef73e825f2db986 170 Pfam PF00583 Acetyltransferase (GNAT) family 31 143 3.8E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS04940 1c9558889f90aafd1ef73e825f2db986 170 SUPERFAMILY SSF55729 23 169 1.03E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS04940 1c9558889f90aafd1ef73e825f2db986 170 Gene3D G3DSA:3.40.630.30 4 170 2.8E-26 T 28-03-2018 CFK41_RS11895 b4ebee2485a696f4fdbc18c29e08b914 116 PIRSF PIRSF002191 1 116 9.2E-49 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS11895 b4ebee2485a696f4fdbc18c29e08b914 116 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 113 29.009 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS11895 b4ebee2485a696f4fdbc18c29e08b914 116 PRINTS PR00061 Ribosomal protein L19 signature 3 32 8.2E-41 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS11895 b4ebee2485a696f4fdbc18c29e08b914 116 PRINTS PR00061 Ribosomal protein L19 signature 87 112 8.2E-41 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS11895 b4ebee2485a696f4fdbc18c29e08b914 116 PRINTS PR00061 Ribosomal protein L19 signature 33 62 8.2E-41 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS11895 b4ebee2485a696f4fdbc18c29e08b914 116 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 2 112 8.9E-47 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS11895 b4ebee2485a696f4fdbc18c29e08b914 116 SUPERFAMILY SSF50104 2 114 1.6E-45 T 28-03-2018 IPR008991 Translation protein SH3-like domain CFK41_RS11895 b4ebee2485a696f4fdbc18c29e08b914 116 ProSitePatterns PS01015 Ribosomal protein L19 signature. 85 100 - T 28-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS11895 b4ebee2485a696f4fdbc18c29e08b914 116 Pfam PF01245 Ribosomal protein L19 4 112 2.5E-48 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS14390 562fd4b6ac6c4cf6bc15fa14082b32a7 106 PIRSF PIRSF029826 1 106 4.2E-36 T 28-03-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 CFK41_RS14390 562fd4b6ac6c4cf6bc15fa14082b32a7 106 SUPERFAMILY SSF101386 6 105 2.76E-31 T 28-03-2018 CFK41_RS14390 562fd4b6ac6c4cf6bc15fa14082b32a7 106 Gene3D G3DSA:1.10.287.1080 1 106 4.0E-22 T 28-03-2018 CFK41_RS14390 562fd4b6ac6c4cf6bc15fa14082b32a7 106 Pfam PF12643 MazG-like family 31 106 1.2E-19 T 28-03-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 CFK41_RS05605 fe49fdcc60a1097e9ca9efec2c99938c 359 Gene3D G3DSA:1.10.10.60 1 26 0.015 T 28-03-2018 CFK41_RS05605 fe49fdcc60a1097e9ca9efec2c99938c 359 SUPERFAMILY SSF47413 10 68 5.34E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS05605 fe49fdcc60a1097e9ca9efec2c99938c 359 Pfam PF13377 Periplasmic binding protein-like domain 174 341 2.9E-35 T 28-03-2018 CFK41_RS05605 fe49fdcc60a1097e9ca9efec2c99938c 359 Gene3D G3DSA:3.40.50.2300 181 325 7.7E-39 T 28-03-2018 CFK41_RS05605 fe49fdcc60a1097e9ca9efec2c99938c 359 SMART SM00354 10 80 4.4E-22 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS05605 fe49fdcc60a1097e9ca9efec2c99938c 359 SUPERFAMILY SSF53822 70 346 2.36E-53 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS05605 fe49fdcc60a1097e9ca9efec2c99938c 359 Gene3D G3DSA:1.10.260.40 27 63 1.7E-18 T 28-03-2018 CFK41_RS05605 fe49fdcc60a1097e9ca9efec2c99938c 359 Pfam PF00356 Bacterial regulatory proteins, lacI family 12 56 9.3E-14 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS05605 fe49fdcc60a1097e9ca9efec2c99938c 359 Gene3D G3DSA:3.40.50.2300 64 180 3.2E-25 T 28-03-2018 CFK41_RS04720 b18dfc36068b47d05b04cd2e5e72a0b5 331 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 19 310 1.8E-112 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS04720 b18dfc36068b47d05b04cd2e5e72a0b5 331 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 218 1.1E-18 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS04720 b18dfc36068b47d05b04cd2e5e72a0b5 331 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 245 302 1.3E-24 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS04720 b18dfc36068b47d05b04cd2e5e72a0b5 331 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 3 311 33.872 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS04720 b18dfc36068b47d05b04cd2e5e72a0b5 331 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 150 2.7E-24 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS04720 b18dfc36068b47d05b04cd2e5e72a0b5 331 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 250 320 5.0E-28 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS04720 b18dfc36068b47d05b04cd2e5e72a0b5 331 SMART SM00662 18 225 9.5E-86 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS04720 b18dfc36068b47d05b04cd2e5e72a0b5 331 SUPERFAMILY SSF55257 170 221 2.16E-24 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS04720 b18dfc36068b47d05b04cd2e5e72a0b5 331 SUPERFAMILY SSF55257 14 48 2.16E-24 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS04720 b18dfc36068b47d05b04cd2e5e72a0b5 331 SUPERFAMILY SSF47789 247 318 1.83E-22 T 28-03-2018 CFK41_RS04720 b18dfc36068b47d05b04cd2e5e72a0b5 331 Gene3D G3DSA:1.10.150.20 239 322 3.6E-24 T 28-03-2018 CFK41_RS04720 b18dfc36068b47d05b04cd2e5e72a0b5 331 Gene3D G3DSA:3.30.1360.10 106 221 4.1E-27 T 28-03-2018 CFK41_RS04720 b18dfc36068b47d05b04cd2e5e72a0b5 331 Gene3D G3DSA:3.30.1360.10 3 84 1.9E-17 T 28-03-2018 CFK41_RS04720 b18dfc36068b47d05b04cd2e5e72a0b5 331 SUPERFAMILY SSF56553 48 169 1.44E-40 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CFK41_RS13265 2392444bac65f5ccb3240552274a15a7 172 Gene3D G3DSA:3.40.50.2300 4 171 3.2E-35 T 28-03-2018 CFK41_RS13265 2392444bac65f5ccb3240552274a15a7 172 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 49 65 2.6E-6 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CFK41_RS13265 2392444bac65f5ccb3240552274a15a7 172 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 6 23 2.6E-6 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CFK41_RS13265 2392444bac65f5ccb3240552274a15a7 172 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 84 99 2.6E-6 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CFK41_RS13265 2392444bac65f5ccb3240552274a15a7 172 SUPERFAMILY SSF52788 2 163 1.57E-28 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CFK41_RS13265 2392444bac65f5ccb3240552274a15a7 172 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 7 158 1.4E-24 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CFK41_RS13265 2392444bac65f5ccb3240552274a15a7 172 SMART SM00226 4 164 1.2E-15 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CFK41_RS11570 67ef50c929c25342e4ef51e3c8a386c8 325 SUPERFAMILY SSF159659 15 284 7.19E-69 T 28-03-2018 CFK41_RS11570 67ef50c929c25342e4ef51e3c8a386c8 325 Pfam PF09754 PAC2 family 32 246 9.3E-39 T 28-03-2018 IPR019151 Proteasome assembly chaperone 2 CFK41_RS11570 67ef50c929c25342e4ef51e3c8a386c8 325 PIRSF PIRSF028754 9 324 4.4E-75 T 28-03-2018 IPR008492 Protein of unknown function DUF774 CFK41_RS11570 67ef50c929c25342e4ef51e3c8a386c8 325 Gene3D G3DSA:1.10.287.100 243 282 3.1E-6 T 28-03-2018 CFK41_RS08695 1193b740760c875772b8d65d284a03ad 228 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 139 161 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CFK41_RS08695 1193b740760c875772b8d65d284a03ad 228 SUPERFAMILY SSF51366 11 221 7.07E-58 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CFK41_RS08695 1193b740760c875772b8d65d284a03ad 228 Pfam PF00834 Ribulose-phosphate 3 epimerase family 12 206 3.8E-69 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CFK41_RS08695 1193b740760c875772b8d65d284a03ad 228 PIRSF PIRSF001461 6 228 7.6E-83 T 28-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CFK41_RS08695 1193b740760c875772b8d65d284a03ad 228 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 12 219 3.8E-75 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CFK41_RS08695 1193b740760c875772b8d65d284a03ad 228 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 37 51 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CFK41_RS08695 1193b740760c875772b8d65d284a03ad 228 Gene3D G3DSA:3.20.20.70 2 222 3.3E-75 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS17285 0c1c6240d3a497ae0a826ca155c8cafd 358 Pfam PF02687 FtsX-like permease family 266 351 6.7E-6 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CFK41_RS09305 0b60119c908d2b78ff7ffcbf8349d275 264 TIGRFAM TIGR01093 aroD: 3-dehydroquinate dehydratase, type I 20 256 3.4E-50 T 28-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CFK41_RS09305 0b60119c908d2b78ff7ffcbf8349d275 264 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 19 262 30.417 T 28-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CFK41_RS09305 0b60119c908d2b78ff7ffcbf8349d275 264 SUPERFAMILY SSF51569 5 262 1.15E-54 T 28-03-2018 CFK41_RS09305 0b60119c908d2b78ff7ffcbf8349d275 264 Gene3D G3DSA:3.20.20.70 3 264 6.1E-68 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS09305 0b60119c908d2b78ff7ffcbf8349d275 264 Pfam PF01487 Type I 3-dehydroquinase 22 256 2.3E-51 T 28-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CFK41_RS16780 cf33bdff2cbc0d68a45f574c3121f970 239 Gene3D G3DSA:1.10.1660.10 57 146 4.0E-7 T 28-03-2018 CFK41_RS16780 cf33bdff2cbc0d68a45f574c3121f970 239 Gene3D G3DSA:1.10.1660.10 1 56 4.2E-17 T 28-03-2018 CFK41_RS16780 cf33bdff2cbc0d68a45f574c3121f970 239 Pfam PF13411 MerR HTH family regulatory protein 6 66 1.4E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS16780 cf33bdff2cbc0d68a45f574c3121f970 239 SMART SM00422 3 72 1.2E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS16780 cf33bdff2cbc0d68a45f574c3121f970 239 SUPERFAMILY SSF46955 4 108 4.76E-22 T 28-03-2018 IPR009061 Putative DNA-binding domain CFK41_RS11265 2ccfdf96e6b35569ed6088df79185bd9 496 SUPERFAMILY SSF55920 225 492 1.03E-66 T 28-03-2018 IPR000994 Peptidase M24 CFK41_RS11265 2ccfdf96e6b35569ed6088df79185bd9 496 Gene3D G3DSA:3.90.230.10 232 496 2.9E-72 T 28-03-2018 CFK41_RS11265 2ccfdf96e6b35569ed6088df79185bd9 496 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 404 416 - T 28-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CFK41_RS11265 2ccfdf96e6b35569ed6088df79185bd9 496 SMART SM01011 39 188 3.6E-35 T 28-03-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 CFK41_RS11265 2ccfdf96e6b35569ed6088df79185bd9 496 Pfam PF05195 Aminopeptidase P, N-terminal domain 46 173 8.7E-23 T 28-03-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 CFK41_RS11265 2ccfdf96e6b35569ed6088df79185bd9 496 Pfam PF00557 Metallopeptidase family M24 231 470 3.6E-54 T 28-03-2018 IPR000994 Peptidase M24 CFK41_RS11265 2ccfdf96e6b35569ed6088df79185bd9 496 Gene3D G3DSA:3.40.350.10 39 231 4.2E-36 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CFK41_RS11265 2ccfdf96e6b35569ed6088df79185bd9 496 SUPERFAMILY SSF53092 46 224 1.41E-24 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CFK41_RS01825 f0de198c7ac390c73159a7b8e7f05413 818 Gene3D G3DSA:2.60.40.1180 723 813 2.7E-30 T 28-03-2018 CFK41_RS01825 f0de198c7ac390c73159a7b8e7f05413 818 SUPERFAMILY SSF48208 323 780 3.23E-50 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CFK41_RS01825 f0de198c7ac390c73159a7b8e7f05413 818 Gene3D G3DSA:1.50.10.10 298 722 7.1E-92 T 28-03-2018 CFK41_RS01825 f0de198c7ac390c73159a7b8e7f05413 818 Pfam PF14498 Glycosyl hydrolase family 65, N-terminal domain 82 299 4.4E-31 T 28-03-2018 IPR027414 Glycosyl hydrolase family 95, N-terminal domain KEGG: 00511+3.2.1.51 CFK41_RS01825 f0de198c7ac390c73159a7b8e7f05413 818 PIRSF PIRSF007663 58 814 1.5E-168 T 28-03-2018 IPR016518 Alpha-L-fucosidase GO:0004560 KEGG: 00511+3.2.1.51 CFK41_RS14855 090ba081b8a0097f0b56f9e913174095 126 Pfam PF01042 Endoribonuclease L-PSP 9 123 4.3E-31 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family CFK41_RS14855 090ba081b8a0097f0b56f9e913174095 126 Gene3D G3DSA:3.30.1330.40 1 126 1.8E-38 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CFK41_RS14855 090ba081b8a0097f0b56f9e913174095 126 SUPERFAMILY SSF55298 4 124 2.98E-38 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CFK41_RS14855 090ba081b8a0097f0b56f9e913174095 126 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 5 122 1.2E-33 T 28-03-2018 IPR006056 RidA family CFK41_RS03195 20e13c97d6130455116cf838fa976f7a 439 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 315 331 2.4E-35 T 28-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CFK41_RS03195 20e13c97d6130455116cf838fa976f7a 439 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 87 103 2.4E-35 T 28-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CFK41_RS03195 20e13c97d6130455116cf838fa976f7a 439 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 404 419 2.4E-35 T 28-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CFK41_RS03195 20e13c97d6130455116cf838fa976f7a 439 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 272 290 2.4E-35 T 28-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CFK41_RS03195 20e13c97d6130455116cf838fa976f7a 439 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 120 140 2.4E-35 T 28-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CFK41_RS03195 20e13c97d6130455116cf838fa976f7a 439 Gene3D G3DSA:3.40.630.10 10 107 5.3E-27 T 28-03-2018 CFK41_RS03195 20e13c97d6130455116cf838fa976f7a 439 Pfam PF02127 Aminopeptidase I zinc metalloprotease (M18) 23 434 7.2E-114 T 28-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CFK41_RS03195 20e13c97d6130455116cf838fa976f7a 439 Gene3D G3DSA:2.30.250.10 108 203 6.2E-32 T 28-03-2018 CFK41_RS03195 20e13c97d6130455116cf838fa976f7a 439 SUPERFAMILY SSF101821 99 212 5.04E-25 T 28-03-2018 CFK41_RS03195 20e13c97d6130455116cf838fa976f7a 439 SUPERFAMILY SSF53187 13 98 4.49E-89 T 28-03-2018 CFK41_RS03195 20e13c97d6130455116cf838fa976f7a 439 SUPERFAMILY SSF53187 214 437 4.49E-89 T 28-03-2018 CFK41_RS03195 20e13c97d6130455116cf838fa976f7a 439 Gene3D G3DSA:3.40.630.10 204 439 5.2E-77 T 28-03-2018 CFK41_RS00085 80710f6dd6d36fb38ef3f30236a17d31 116 Gene3D G3DSA:1.10.10.10 6 100 2.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS00085 80710f6dd6d36fb38ef3f30236a17d31 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 7.0E-10 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS00085 80710f6dd6d36fb38ef3f30236a17d31 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 22 37 7.0E-10 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS00085 80710f6dd6d36fb38ef3f30236a17d31 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 7.0E-10 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS00085 80710f6dd6d36fb38ef3f30236a17d31 116 SUPERFAMILY SSF46785 8 98 2.8E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS00085 80710f6dd6d36fb38ef3f30236a17d31 116 Pfam PF12840 Helix-turn-helix domain 21 78 2.0E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS00085 80710f6dd6d36fb38ef3f30236a17d31 116 SMART SM00418 20 98 1.8E-24 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS16260 b7b91356438c4e3af21afbd78c9d8640 341 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 138 234 4.4E-11 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CFK41_RS16260 b7b91356438c4e3af21afbd78c9d8640 341 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 113 5.0E-22 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS16260 b7b91356438c4e3af21afbd78c9d8640 341 SUPERFAMILY SSF51735 4 157 4.86E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS16260 b7b91356438c4e3af21afbd78c9d8640 341 SUPERFAMILY SSF55347 134 280 4.25E-26 T 28-03-2018 CFK41_RS16260 b7b91356438c4e3af21afbd78c9d8640 341 Gene3D G3DSA:3.30.360.10 137 338 7.8E-37 T 28-03-2018 CFK41_RS16260 b7b91356438c4e3af21afbd78c9d8640 341 Gene3D G3DSA:3.40.50.720 1 136 7.2E-34 T 28-03-2018 CFK41_RS13320 7cccb888fd287982ff1deb9d283ea7b5 265 Gene3D G3DSA:1.10.10.10 5 85 1.5E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS13320 7cccb888fd287982ff1deb9d283ea7b5 265 Pfam PF07729 FCD domain 93 227 1.9E-13 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS13320 7cccb888fd287982ff1deb9d283ea7b5 265 SUPERFAMILY SSF46785 12 109 5.3E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS13320 7cccb888fd287982ff1deb9d283ea7b5 265 SUPERFAMILY SSF48008 92 234 6.28E-18 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS13320 7cccb888fd287982ff1deb9d283ea7b5 265 SMART SM00345 25 83 6.4E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS13320 7cccb888fd287982ff1deb9d283ea7b5 265 Pfam PF00392 Bacterial regulatory proteins, gntR family 23 83 2.0E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS13320 7cccb888fd287982ff1deb9d283ea7b5 265 Gene3D G3DSA:1.20.120.530 86 241 4.5E-20 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS13320 7cccb888fd287982ff1deb9d283ea7b5 265 SMART SM00895 93 228 3.5E-5 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS01565 a9aed0e816d79618b154def2131d3602 502 PIRSF PIRSF001478 2 500 5.6E-230 T 28-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 CFK41_RS01565 a9aed0e816d79618b154def2131d3602 502 SUPERFAMILY SSF53743 4 328 9.81E-118 T 28-03-2018 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 CFK41_RS01565 a9aed0e816d79618b154def2131d3602 502 SUPERFAMILY SSF50443 330 498 1.78E-63 T 28-03-2018 IPR004216 L-fucose/L-arabinose isomerase, C-terminal CFK41_RS01565 a9aed0e816d79618b154def2131d3602 502 Pfam PF11762 L-arabinose isomerase C-terminal domain 363 476 4.7E-46 T 28-03-2018 IPR024664 L-arabinose isomerase, C-terminal KEGG: 00040+5.3.1.4 CFK41_RS01565 a9aed0e816d79618b154def2131d3602 502 ProDom PD018364 ISOMERASE L-ARABINOSE ARABINOSE METABOLISM CARBOHYDRATE CATABOLISM ARAA 9 305 1.0E-120 T 28-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 CFK41_RS01565 a9aed0e816d79618b154def2131d3602 502 Hamap MF_00519 L-arabinose isomerase [araA]. 2 477 62.596 T 28-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 CFK41_RS01565 a9aed0e816d79618b154def2131d3602 502 Pfam PF02610 L-arabinose isomerase 6 359 1.6E-173 T 28-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 CFK41_RS05025 d6fc9d11f7c44c697b90238346f9cbe9 97 SUPERFAMILY SSF116842 30 87 5.62E-16 T 28-03-2018 CFK41_RS05025 d6fc9d11f7c44c697b90238346f9cbe9 97 PIRSF PIRSF006488 22 96 4.7E-20 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CFK41_RS05025 d6fc9d11f7c44c697b90238346f9cbe9 97 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 34 77 6.0E-10 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CFK41_RS05025 d6fc9d11f7c44c697b90238346f9cbe9 97 Gene3D G3DSA:1.10.287.1040 34 95 1.8E-18 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CFK41_RS05025 d6fc9d11f7c44c697b90238346f9cbe9 97 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 36 96 13.211 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CFK41_RS05025 d6fc9d11f7c44c697b90238346f9cbe9 97 Pfam PF02609 Exonuclease VII small subunit 37 86 8.2E-16 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CFK41_RS05025 d6fc9d11f7c44c697b90238346f9cbe9 97 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 36 89 1.7E-18 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CFK41_RS04425 dc899e55d929a81124d52412dbff8e0b 190 Pfam PF00551 Formyl transferase 6 183 2.3E-48 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CFK41_RS04425 dc899e55d929a81124d52412dbff8e0b 190 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 5 189 27.194 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CFK41_RS04425 dc899e55d929a81124d52412dbff8e0b 190 SUPERFAMILY SSF53328 6 186 6.93E-53 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CFK41_RS04425 dc899e55d929a81124d52412dbff8e0b 190 Gene3D G3DSA:3.40.50.170 2 189 4.5E-63 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CFK41_RS04425 dc899e55d929a81124d52412dbff8e0b 190 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 6 187 4.5E-62 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CFK41_RS04425 dc899e55d929a81124d52412dbff8e0b 190 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 135 158 - T 28-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CFK41_RS03165 9d7dcd64ce3396b1150b2d0a81fe6a12 481 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 3 471 5.4E-35 T 28-03-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CFK41_RS03165 9d7dcd64ce3396b1150b2d0a81fe6a12 481 Gene3D G3DSA:1.10.3110.10 124 205 4.7E-18 T 28-03-2018 CFK41_RS03165 9d7dcd64ce3396b1150b2d0a81fe6a12 481 Pfam PF01593 Flavin containing amine oxidoreductase 12 331 3.7E-23 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CFK41_RS03165 9d7dcd64ce3396b1150b2d0a81fe6a12 481 SUPERFAMILY SSF54373 314 431 3.92E-8 T 28-03-2018 CFK41_RS03165 9d7dcd64ce3396b1150b2d0a81fe6a12 481 Gene3D G3DSA:3.40.50.720 3 123 6.6E-11 T 28-03-2018 CFK41_RS03165 9d7dcd64ce3396b1150b2d0a81fe6a12 481 SUPERFAMILY SSF51905 448 466 5.96E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS03165 9d7dcd64ce3396b1150b2d0a81fe6a12 481 SUPERFAMILY SSF51905 4 329 5.96E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS03165 9d7dcd64ce3396b1150b2d0a81fe6a12 481 Gene3D G3DSA:3.90.660.20 248 431 5.3E-28 T 28-03-2018 CFK41_RS14610 e9b5809d1836bba40114e3764cba7345 1178 SMART SM00479 46 211 4.5E-28 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CFK41_RS14610 e9b5809d1836bba40114e3764cba7345 1178 SUPERFAMILY SSF52540 543 838 2.48E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS14610 e9b5809d1836bba40114e3764cba7345 1178 Gene3D G3DSA:3.40.50.300 237 584 4.9E-22 T 28-03-2018 CFK41_RS14610 e9b5809d1836bba40114e3764cba7345 1178 SMART SM00382 431 584 2.2E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS14610 e9b5809d1836bba40114e3764cba7345 1178 Pfam PF02689 Helicase 776 836 3.1E-5 T 28-03-2018 IPR003840 DNA helicase GO:0004386|GO:0005524 CFK41_RS14610 e9b5809d1836bba40114e3764cba7345 1178 Gene3D G3DSA:3.30.420.10 43 211 1.3E-33 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CFK41_RS14610 e9b5809d1836bba40114e3764cba7345 1178 SUPERFAMILY SSF52540 414 561 1.38E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS14610 e9b5809d1836bba40114e3764cba7345 1178 Pfam PF00929 Exonuclease 49 201 9.0E-22 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CFK41_RS14610 e9b5809d1836bba40114e3764cba7345 1178 Pfam PF05970 PIF1-like helicase 428 568 3.1E-26 T 28-03-2018 IPR010285 DNA helicase Pif1-like GO:0000723|GO:0003678|GO:0006281 CFK41_RS14610 e9b5809d1836bba40114e3764cba7345 1178 SUPERFAMILY SSF53098 46 211 5.06E-44 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CFK41_RS14610 e9b5809d1836bba40114e3764cba7345 1178 Gene3D G3DSA:3.30.420.10 844 955 0.029 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CFK41_RS14610 e9b5809d1836bba40114e3764cba7345 1178 Gene3D G3DSA:3.40.50.10190 1102 1178 3.3E-8 T 28-03-2018 IPR001357 BRCT domain CFK41_RS06005 cecf7d7853ecd1c92c11f1c0a1bcd4e2 125 Gene3D G3DSA:1.20.1300.10 3 116 6.1E-24 T 28-03-2018 CFK41_RS06005 cecf7d7853ecd1c92c11f1c0a1bcd4e2 125 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 9 112 4.4E-25 T 28-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CFK41_RS06005 cecf7d7853ecd1c92c11f1c0a1bcd4e2 125 PIRSF PIRSF000178 8 119 6.9E-8 T 28-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CFK41_RS06005 cecf7d7853ecd1c92c11f1c0a1bcd4e2 125 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 8 111 4.7E-21 T 28-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CFK41_RS06005 cecf7d7853ecd1c92c11f1c0a1bcd4e2 125 SUPERFAMILY SSF81343 8 115 9.59E-25 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CFK41_RS12525 e18a908890be1529518be75c1b4dcc8c 287 Pfam PF02104 SURF1 family 19 226 8.2E-16 T 28-03-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS02635 22de0ece32b049bfc9bd3ff1ee1a0d1d 183 Gene3D G3DSA:1.10.10.10 12 159 9.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS02635 22de0ece32b049bfc9bd3ff1ee1a0d1d 183 SMART SM00347 36 140 6.5E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS02635 22de0ece32b049bfc9bd3ff1ee1a0d1d 183 ProSitePatterns PS01117 MarR-type HTH domain signature. 79 113 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CFK41_RS02635 22de0ece32b049bfc9bd3ff1ee1a0d1d 183 SUPERFAMILY SSF46785 15 156 2.51E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS02635 22de0ece32b049bfc9bd3ff1ee1a0d1d 183 Pfam PF01047 MarR family 63 105 7.0E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS12250 dcc6914d03f028a3de7e0504d514be23 272 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 11 254 27.505 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CFK41_RS12250 dcc6914d03f028a3de7e0504d514be23 272 SUPERFAMILY SSF53335 54 251 1.18E-19 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS12250 dcc6914d03f028a3de7e0504d514be23 272 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 52 202 4.5E-37 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CFK41_RS12250 dcc6914d03f028a3de7e0504d514be23 272 Gene3D G3DSA:3.40.50.150 17 261 2.2E-22 T 28-03-2018 CFK41_RS12250 dcc6914d03f028a3de7e0504d514be23 272 Pfam PF02390 Putative methyltransferase 62 210 2.1E-38 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CFK41_RS06345 137a4b512425f4ed4712dd63967a827c 567 Pfam PF10647 Lipoprotein LpqB beta-propeller domain 337 564 1.0E-25 T 28-03-2018 IPR018910 Lipoprotein LpqB, beta-propeller domain, C-terminal CFK41_RS06345 137a4b512425f4ed4712dd63967a827c 567 Pfam PF10646 Sporulation and spore germination 181 291 3.7E-6 T 28-03-2018 IPR019606 GerMN domain CFK41_RS06345 137a4b512425f4ed4712dd63967a827c 567 Gene3D G3DSA:2.140.10.30 36 525 5.3E-5 T 28-03-2018 CFK41_RS00175 141b8ef78ecbb568e6c1c6a1b9d61b8b 213 Gene3D G3DSA:3.40.50.720 2 207 3.0E-26 T 28-03-2018 CFK41_RS00175 141b8ef78ecbb568e6c1c6a1b9d61b8b 213 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 91 2.0E-18 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CFK41_RS00175 141b8ef78ecbb568e6c1c6a1b9d61b8b 213 SUPERFAMILY SSF51735 4 196 1.11E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS14960 ca0816dc33b2a7131d0744e86552e40d 340 SUPERFAMILY SSF53807 42 329 1.22E-36 T 28-03-2018 CFK41_RS14960 ca0816dc33b2a7131d0744e86552e40d 340 Gene3D G3DSA:3.40.50.1980 43 178 1.3E-18 T 28-03-2018 CFK41_RS14960 ca0816dc33b2a7131d0744e86552e40d 340 Gene3D G3DSA:3.40.50.1980 179 336 2.3E-27 T 28-03-2018 CFK41_RS14960 ca0816dc33b2a7131d0744e86552e40d 340 Pfam PF01497 Periplasmic binding protein 67 303 5.3E-18 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CFK41_RS16660 a608d655125d91a55b0f01d683fb5c80 363 Pfam PF00775 Dioxygenase 144 223 6.4E-10 T 28-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CFK41_RS16660 a608d655125d91a55b0f01d683fb5c80 363 Gene3D G3DSA:2.60.130.10 69 320 1.2E-45 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CFK41_RS16660 a608d655125d91a55b0f01d683fb5c80 363 SUPERFAMILY SSF49482 102 315 1.96E-43 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CFK41_RS07610 20c4d0a6cd3a5202c14b167d5ff72818 256 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 66 247 4.3E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS07610 20c4d0a6cd3a5202c14b167d5ff72818 256 SUPERFAMILY SSF161098 6 252 3.55E-51 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS07610 20c4d0a6cd3a5202c14b167d5ff72818 256 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 49 251 1.0E-67 T 28-03-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 CFK41_RS07610 20c4d0a6cd3a5202c14b167d5ff72818 256 TIGRFAM TIGR01581 Mo_ABC_porter: NifC-like ABC-type porter 27 246 1.2E-79 T 28-03-2018 IPR006469 NifC-like ABC-type porter GO:0005215|GO:0006810|GO:0016020 CFK41_RS07610 20c4d0a6cd3a5202c14b167d5ff72818 256 Gene3D G3DSA:1.10.3720.10 6 254 2.0E-38 T 28-03-2018 CFK41_RS14375 7fe871777cbeed283cd6be9d3556aaa3 766 SUPERFAMILY SSF51905 274 286 4.15E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS14375 7fe871777cbeed283cd6be9d3556aaa3 766 SUPERFAMILY SSF51905 352 422 4.15E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS14375 7fe871777cbeed283cd6be9d3556aaa3 766 SUPERFAMILY SSF51905 29 224 4.15E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS14375 7fe871777cbeed283cd6be9d3556aaa3 766 Gene3D G3DSA:3.50.50.60 27 440 5.1E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS14375 7fe871777cbeed283cd6be9d3556aaa3 766 Gene3D G3DSA:2.60.120.260 453 765 6.7E-12 T 28-03-2018 IPR008979 Galactose-binding domain-like CFK41_RS14375 7fe871777cbeed283cd6be9d3556aaa3 766 Pfam PF12831 FAD dependent oxidoreductase 34 446 2.3E-96 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS14900 dc69dda5eaedab8147e96e4fe6de8c32 368 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 84 98 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CFK41_RS14900 dc69dda5eaedab8147e96e4fe6de8c32 368 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 232 244 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CFK41_RS14900 dc69dda5eaedab8147e96e4fe6de8c32 368 SUPERFAMILY SSF48576 27 327 9.59E-59 T 28-03-2018 IPR008949 Isoprenoid synthase domain CFK41_RS14900 dc69dda5eaedab8147e96e4fe6de8c32 368 Pfam PF00348 Polyprenyl synthetase 40 276 3.9E-48 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CFK41_RS14900 dc69dda5eaedab8147e96e4fe6de8c32 368 Gene3D G3DSA:1.10.600.10 2 349 1.4E-71 T 28-03-2018 IPR008949 Isoprenoid synthase domain CFK41_RS16165 f7a40cb02f9404828d90e7a564e7381d 305 SUPERFAMILY SSF144091 81 256 4.05E-37 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CFK41_RS16165 f7a40cb02f9404828d90e7a564e7381d 305 Gene3D G3DSA:1.20.1540.10 81 258 1.7E-36 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CFK41_RS16165 f7a40cb02f9404828d90e7a564e7381d 305 Pfam PF01694 Rhomboid family 122 256 3.7E-28 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CFK41_RS00150 90372ee10f72439d09b040f64781e575 313 SUPERFAMILY SSF51430 1 302 1.96E-95 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS00150 90372ee10f72439d09b040f64781e575 313 Pfam PF00248 Aldo/keto reductase family 15 299 1.0E-70 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS00150 90372ee10f72439d09b040f64781e575 313 PRINTS PR00069 Aldo-keto reductase signature 39 63 6.5E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS00150 90372ee10f72439d09b040f64781e575 313 PRINTS PR00069 Aldo-keto reductase signature 140 157 6.5E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS00150 90372ee10f72439d09b040f64781e575 313 Gene3D G3DSA:3.20.20.100 3 301 1.5E-91 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS12685 d74b5f4cef60b4213559c1c3228edd90 574 SUPERFAMILY SSF53850 66 573 3.1E-80 T 28-03-2018 CFK41_RS12685 d74b5f4cef60b4213559c1c3228edd90 574 Gene3D G3DSA:3.40.190.10 227 326 4.9E-22 T 28-03-2018 CFK41_RS12685 d74b5f4cef60b4213559c1c3228edd90 574 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 118 491 1.4E-54 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CFK41_RS12685 d74b5f4cef60b4213559c1c3228edd90 574 Gene3D G3DSA:3.90.76.10 105 214 7.5E-11 T 28-03-2018 CFK41_RS12685 d74b5f4cef60b4213559c1c3228edd90 574 Gene3D G3DSA:3.10.105.10 327 543 7.7E-48 T 28-03-2018 CFK41_RS12685 d74b5f4cef60b4213559c1c3228edd90 574 PIRSF PIRSF002741 7 570 1.2E-52 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CFK41_RS03340 ec652f11895869698d5b326fe6659412 1119 Gene3D G3DSA:1.20.5.170 405 551 0.0088 T 28-03-2018 CFK41_RS03340 ec652f11895869698d5b326fe6659412 1119 Gene3D G3DSA:3.40.1140.10 20 170 2.7E-7 T 28-03-2018 CFK41_RS03340 ec652f11895869698d5b326fe6659412 1119 Pfam PF13555 P-loop containing region of AAA domain 25 84 9.5E-21 T 28-03-2018 CFK41_RS03340 ec652f11895869698d5b326fe6659412 1119 SUPERFAMILY SSF52540 993 1076 1.31E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS03340 ec652f11895869698d5b326fe6659412 1119 SUPERFAMILY SSF52540 26 181 1.31E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS03340 ec652f11895869698d5b326fe6659412 1119 Gene3D G3DSA:1.20.5.1000 314 397 3.7E-4 T 28-03-2018 CFK41_RS03340 ec652f11895869698d5b326fe6659412 1119 Pfam PF13558 Putative exonuclease SbcCD, C subunit 982 1068 3.5E-18 T 28-03-2018 CFK41_RS15560 cf4ba3d8ac6f3c3b0c30f08044a9adc4 228 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 57 228 1.4E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS15560 cf4ba3d8ac6f3c3b0c30f08044a9adc4 228 SUPERFAMILY SSF161098 17 215 6.41E-42 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS15560 cf4ba3d8ac6f3c3b0c30f08044a9adc4 228 Gene3D G3DSA:1.10.3720.10 11 226 5.1E-36 T 28-03-2018 CFK41_RS17295 7fbd5b76ebb14cfa865b2cb36468c2bb 203 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 61 143 2.1E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CFK41_RS17295 7fbd5b76ebb14cfa865b2cb36468c2bb 203 Pfam PF13419 Haloacid dehalogenase-like hydrolase 46 146 8.1E-14 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS17295 7fbd5b76ebb14cfa865b2cb36468c2bb 203 Gene3D G3DSA:3.40.50.1000 27 188 1.2E-27 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS17295 7fbd5b76ebb14cfa865b2cb36468c2bb 203 SUPERFAMILY SSF56784 17 182 1.28E-28 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS01045 4a264d874757147272cf99181c026ab6 266 SUPERFAMILY SSF53613 2 248 3.12E-56 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS01045 4a264d874757147272cf99181c026ab6 266 Gene3D G3DSA:3.40.1190.20 1 260 2.7E-46 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS01045 4a264d874757147272cf99181c026ab6 266 Pfam PF08543 Phosphomethylpyrimidine kinase 13 249 1.4E-63 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CFK41_RS01195 704858ffacabf834e97803a8702851a3 451 Gene3D G3DSA:1.20.1250.20 241 445 9.1E-17 T 28-03-2018 CFK41_RS01195 704858ffacabf834e97803a8702851a3 451 Pfam PF07690 Major Facilitator Superfamily 38 285 1.6E-20 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS01195 704858ffacabf834e97803a8702851a3 451 SUPERFAMILY SSF103473 20 437 3.66E-48 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS01195 704858ffacabf834e97803a8702851a3 451 Gene3D G3DSA:1.20.1250.20 26 238 2.7E-19 T 28-03-2018 CFK41_RS07140 8c04ac0b5bff83c4c769b928b3a0942d 331 SUPERFAMILY SSF53300 64 213 5.19E-19 T 28-03-2018 IPR002035 von Willebrand factor, type A CFK41_RS07140 8c04ac0b5bff83c4c769b928b3a0942d 331 SUPERFAMILY SSF53300 242 265 5.19E-19 T 28-03-2018 IPR002035 von Willebrand factor, type A CFK41_RS07140 8c04ac0b5bff83c4c769b928b3a0942d 331 Pfam PF13519 von Willebrand factor type A domain 71 185 1.1E-10 T 28-03-2018 IPR002035 von Willebrand factor, type A CFK41_RS07140 8c04ac0b5bff83c4c769b928b3a0942d 331 SMART SM00327 67 273 5.4E-6 T 28-03-2018 IPR002035 von Willebrand factor, type A CFK41_RS07140 8c04ac0b5bff83c4c769b928b3a0942d 331 Gene3D G3DSA:3.40.50.410 60 276 3.9E-22 T 28-03-2018 IPR002035 von Willebrand factor, type A CFK41_RS06340 09306e71e766172a31e9c4a2fdc2e492 573 SUPERFAMILY SSF55874 346 513 1.44E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS06340 09306e71e766172a31e9c4a2fdc2e492 573 Pfam PF00672 HAMP domain 229 278 8.5E-14 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CFK41_RS06340 09306e71e766172a31e9c4a2fdc2e492 573 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 403 511 1.4E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS06340 09306e71e766172a31e9c4a2fdc2e492 573 SMART SM00388 289 356 4.0E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CFK41_RS06340 09306e71e766172a31e9c4a2fdc2e492 573 Gene3D G3DSA:1.10.287.130 272 350 1.4E-13 T 28-03-2018 CFK41_RS06340 09306e71e766172a31e9c4a2fdc2e492 573 SMART SM00304 229 281 3.9E-16 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CFK41_RS06340 09306e71e766172a31e9c4a2fdc2e492 573 SMART SM00387 402 513 2.2E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS06340 09306e71e766172a31e9c4a2fdc2e492 573 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 466 5.1E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS06340 09306e71e766172a31e9c4a2fdc2e492 573 PRINTS PR00344 Bacterial sensor protein C-terminal signature 473 491 5.1E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS06340 09306e71e766172a31e9c4a2fdc2e492 573 PRINTS PR00344 Bacterial sensor protein C-terminal signature 497 510 5.1E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS06340 09306e71e766172a31e9c4a2fdc2e492 573 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 452 5.1E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS06340 09306e71e766172a31e9c4a2fdc2e492 573 Gene3D G3DSA:3.30.565.10 351 513 4.1E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS06340 09306e71e766172a31e9c4a2fdc2e492 573 SUPERFAMILY SSF47384 272 356 1.47E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CFK41_RS06340 09306e71e766172a31e9c4a2fdc2e492 573 SUPERFAMILY SSF158472 229 278 1.28E-10 T 28-03-2018 CFK41_RS06340 09306e71e766172a31e9c4a2fdc2e492 573 Pfam PF00512 His Kinase A (phospho-acceptor) domain 290 356 5.3E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CFK41_RS09355 1eb5a0817287518cdb8d54dc6ece161d 454 Pfam PF13458 Periplasmic binding protein 54 378 7.0E-10 T 28-03-2018 IPR028081 Leucine-binding protein domain CFK41_RS09355 1eb5a0817287518cdb8d54dc6ece161d 454 Gene3D G3DSA:3.40.50.2300 174 379 1.4E-9 T 28-03-2018 CFK41_RS09355 1eb5a0817287518cdb8d54dc6ece161d 454 Gene3D G3DSA:3.40.50.2300 52 173 0.014 T 28-03-2018 CFK41_RS09355 1eb5a0817287518cdb8d54dc6ece161d 454 SUPERFAMILY SSF53822 50 380 6.67E-16 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS16485 d1d1f73e2bcf9259cc583ed713072ed7 385 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 122 3.2E-29 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS16485 d1d1f73e2bcf9259cc583ed713072ed7 385 SUPERFAMILY SSF55347 132 290 5.72E-25 T 28-03-2018 CFK41_RS16485 d1d1f73e2bcf9259cc583ed713072ed7 385 Gene3D G3DSA:3.30.360.10 138 350 9.1E-40 T 28-03-2018 CFK41_RS16485 d1d1f73e2bcf9259cc583ed713072ed7 385 Gene3D G3DSA:3.40.50.720 1 137 4.3E-40 T 28-03-2018 CFK41_RS16485 d1d1f73e2bcf9259cc583ed713072ed7 385 SUPERFAMILY SSF51735 2 158 1.07E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS16485 d1d1f73e2bcf9259cc583ed713072ed7 385 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 136 227 1.2E-11 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CFK41_RS07265 d4aa435171503a67b4cdbdd59bb6e500 543 Pfam PF08502 LeuA allosteric (dimerisation) domain 392 536 1.1E-22 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CFK41_RS07265 d4aa435171503a67b4cdbdd59bb6e500 543 SUPERFAMILY SSF51569 14 310 2.2E-71 T 28-03-2018 CFK41_RS07265 d4aa435171503a67b4cdbdd59bb6e500 543 SMART SM00917 392 538 4.1E-33 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CFK41_RS07265 d4aa435171503a67b4cdbdd59bb6e500 543 Gene3D G3DSA:3.20.20.70 1 366 6.2E-91 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS07265 d4aa435171503a67b4cdbdd59bb6e500 543 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 103 114 - T 28-03-2018 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 CFK41_RS07265 d4aa435171503a67b4cdbdd59bb6e500 543 SUPERFAMILY SSF110921 424 533 3.92E-17 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CFK41_RS07265 d4aa435171503a67b4cdbdd59bb6e500 543 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 220 233 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CFK41_RS07265 d4aa435171503a67b4cdbdd59bb6e500 543 Pfam PF00682 HMGL-like 16 272 2.5E-45 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CFK41_RS07265 d4aa435171503a67b4cdbdd59bb6e500 543 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 22 38 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CFK41_RS07265 d4aa435171503a67b4cdbdd59bb6e500 543 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 16 540 8.1E-176 T 28-03-2018 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 CFK41_RS15125 e2d42f1d6670170666b21ed9a0c924f7 576 SUPERFAMILY SSF90123 18 301 4.58E-13 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS15125 e2d42f1d6670170666b21ed9a0c924f7 576 Pfam PF00005 ABC transporter 350 504 7.6E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS15125 e2d42f1d6670170666b21ed9a0c924f7 576 SUPERFAMILY SSF52540 332 574 4.55E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS15125 e2d42f1d6670170666b21ed9a0c924f7 576 Gene3D G3DSA:3.40.50.300 330 576 1.1E-54 T 28-03-2018 CFK41_RS15125 e2d42f1d6670170666b21ed9a0c924f7 576 SMART SM00382 359 556 1.6E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS15125 e2d42f1d6670170666b21ed9a0c924f7 576 Gene3D G3DSA:1.20.1560.10 3 311 4.9E-7 T 28-03-2018 CFK41_RS08460 21627539457c385e86620328dda4a65d 318 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 57 317 4.3E-87 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CFK41_RS08460 21627539457c385e86620328dda4a65d 318 Gene3D G3DSA:3.20.20.60 43 317 2.2E-78 T 28-03-2018 CFK41_RS08460 21627539457c385e86620328dda4a65d 318 PIRSF PIRSF000388 49 318 2.9E-94 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CFK41_RS08460 21627539457c385e86620328dda4a65d 318 Pfam PF02548 Ketopantoate hydroxymethyltransferase 57 312 2.7E-100 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CFK41_RS08460 21627539457c385e86620328dda4a65d 318 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 58 317 38.799 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CFK41_RS08460 21627539457c385e86620328dda4a65d 318 SUPERFAMILY SSF51621 58 317 5.1E-92 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CFK41_RS13290 d9c249a9c6850fe14d51a7ffc1c0edf7 942 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 154 165 - T 28-03-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CFK41_RS13290 d9c249a9c6850fe14d51a7ffc1c0edf7 942 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 20 942 17.746 T 28-03-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CFK41_RS13290 d9c249a9c6850fe14d51a7ffc1c0edf7 942 SUPERFAMILY SSF51621 31 942 8.32E-266 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CFK41_RS13290 d9c249a9c6850fe14d51a7ffc1c0edf7 942 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 153 166 8.8E-62 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CFK41_RS13290 d9c249a9c6850fe14d51a7ffc1c0edf7 942 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 204 220 8.8E-62 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CFK41_RS13290 d9c249a9c6850fe14d51a7ffc1c0edf7 942 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 631 660 8.8E-62 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CFK41_RS13290 d9c249a9c6850fe14d51a7ffc1c0edf7 942 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 417 437 8.8E-62 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CFK41_RS13290 d9c249a9c6850fe14d51a7ffc1c0edf7 942 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 768 794 8.8E-62 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CFK41_RS13290 d9c249a9c6850fe14d51a7ffc1c0edf7 942 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 589 609 8.8E-62 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CFK41_RS13290 d9c249a9c6850fe14d51a7ffc1c0edf7 942 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 262 277 8.8E-62 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CFK41_RS13290 d9c249a9c6850fe14d51a7ffc1c0edf7 942 Gene3D G3DSA:1.20.1440.90 291 419 7.1E-22 T 28-03-2018 CFK41_RS13290 d9c249a9c6850fe14d51a7ffc1c0edf7 942 Pfam PF00311 Phosphoenolpyruvate carboxylase 149 942 9.8E-288 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CFK41_RS10270 a0bd80b651cc0db06a14eb2340b0c216 56 Pfam PF01783 Ribosomal L32p protein family 2 46 4.3E-11 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS10270 a0bd80b651cc0db06a14eb2340b0c216 56 SUPERFAMILY SSF57829 1 34 1.34E-6 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CFK41_RS10270 a0bd80b651cc0db06a14eb2340b0c216 56 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 34 7.6E-9 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS10270 a0bd80b651cc0db06a14eb2340b0c216 56 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 52 12.489 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS14015 56f2f7991ce8595d82fa6018ecf12964 425 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 49 57 1.2E-9 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CFK41_RS14015 56f2f7991ce8595d82fa6018ecf12964 425 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 148 162 1.2E-9 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CFK41_RS14015 56f2f7991ce8595d82fa6018ecf12964 425 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 81 92 1.2E-9 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CFK41_RS14015 56f2f7991ce8595d82fa6018ecf12964 425 Gene3D G3DSA:3.40.50.1820 28 188 3.6E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS14015 56f2f7991ce8595d82fa6018ecf12964 425 SUPERFAMILY SSF53474 29 178 1.12E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS14015 56f2f7991ce8595d82fa6018ecf12964 425 SUPERFAMILY SSF53474 259 417 1.12E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS14015 56f2f7991ce8595d82fa6018ecf12964 425 Gene3D G3DSA:3.40.50.1820 189 420 1.3E-7 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS14015 56f2f7991ce8595d82fa6018ecf12964 425 Pfam PF00561 alpha/beta hydrolase fold 48 190 3.0E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CFK41_RS13180 57d5e3c1eeddaeed9518e6a4aa04de5c 196 Gene3D G3DSA:1.10.357.10 59 192 3.6E-15 T 28-03-2018 CFK41_RS13180 57d5e3c1eeddaeed9518e6a4aa04de5c 196 Gene3D G3DSA:1.10.10.60 1 58 2.8E-16 T 28-03-2018 CFK41_RS13180 57d5e3c1eeddaeed9518e6a4aa04de5c 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 58 6.0E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS13180 57d5e3c1eeddaeed9518e6a4aa04de5c 196 SUPERFAMILY SSF48498 83 189 4.05E-7 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CFK41_RS13180 57d5e3c1eeddaeed9518e6a4aa04de5c 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 7.0E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS13180 57d5e3c1eeddaeed9518e6a4aa04de5c 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 7.0E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS13180 57d5e3c1eeddaeed9518e6a4aa04de5c 196 SUPERFAMILY SSF46689 1 67 4.87E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS02405 459b0d104342de6898ccfbbed3268313 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 138 309 3.5E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS02405 459b0d104342de6898ccfbbed3268313 314 Gene3D G3DSA:1.10.3720.10 54 313 8.7E-28 T 28-03-2018 CFK41_RS02405 459b0d104342de6898ccfbbed3268313 314 SUPERFAMILY SSF161098 115 297 3.14E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS10235 929a335c208b9a96548057da384a0a6f 213 SUPERFAMILY SSF48498 102 201 4.15E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CFK41_RS10235 929a335c208b9a96548057da384a0a6f 213 Gene3D G3DSA:1.10.10.60 1 67 9.4E-19 T 28-03-2018 CFK41_RS10235 929a335c208b9a96548057da384a0a6f 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 6.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS10235 929a335c208b9a96548057da384a0a6f 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 6.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS10235 929a335c208b9a96548057da384a0a6f 213 ProSitePatterns PS01081 TetR-type HTH domain signature. 35 65 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CFK41_RS10235 929a335c208b9a96548057da384a0a6f 213 SUPERFAMILY SSF46689 9 90 7.7E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS10235 929a335c208b9a96548057da384a0a6f 213 Gene3D G3DSA:1.10.357.10 68 205 7.9E-19 T 28-03-2018 CFK41_RS10235 929a335c208b9a96548057da384a0a6f 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 67 2.0E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS10690 be58f90968dac3fd62817d2567664689 175 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 48 64 1.3E-19 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CFK41_RS10690 be58f90968dac3fd62817d2567664689 175 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 126 141 1.3E-19 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CFK41_RS10690 be58f90968dac3fd62817d2567664689 175 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 82 97 1.3E-19 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CFK41_RS10690 be58f90968dac3fd62817d2567664689 175 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 5 22 1.3E-19 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CFK41_RS10690 be58f90968dac3fd62817d2567664689 175 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 5 149 1.3E-36 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CFK41_RS10690 be58f90968dac3fd62817d2567664689 175 SMART SM00226 3 154 2.9E-38 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CFK41_RS10690 be58f90968dac3fd62817d2567664689 175 SUPERFAMILY SSF52788 1 152 4.45E-44 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CFK41_RS10690 be58f90968dac3fd62817d2567664689 175 Gene3D G3DSA:3.40.50.2300 2 162 2.6E-48 T 28-03-2018 CFK41_RS02935 980a61f92ad3a8803ae7341184326f2d 399 SUPERFAMILY SSF55347 199 289 1.83E-14 T 28-03-2018 CFK41_RS02935 980a61f92ad3a8803ae7341184326f2d 399 Gene3D G3DSA:3.40.50.720 24 170 1.4E-27 T 28-03-2018 CFK41_RS02935 980a61f92ad3a8803ae7341184326f2d 399 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 32 153 1.4E-11 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS02935 980a61f92ad3a8803ae7341184326f2d 399 Gene3D G3DSA:3.30.360.10 171 372 4.3E-27 T 28-03-2018 CFK41_RS02935 980a61f92ad3a8803ae7341184326f2d 399 SUPERFAMILY SSF51735 23 168 4.32E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS02935 980a61f92ad3a8803ae7341184326f2d 399 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 193 251 3.6E-5 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CFK41_RS13475 8de3bb9e5e75f11afefa70fc49d63a2b 423 PIRSF PIRSF001529 1 419 2.5E-128 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CFK41_RS13475 8de3bb9e5e75f11afefa70fc49d63a2b 423 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 415 36.313 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CFK41_RS13475 8de3bb9e5e75f11afefa70fc49d63a2b 423 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 218 393 9.0E-27 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS13475 8de3bb9e5e75f11afefa70fc49d63a2b 423 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 410 9.7E-123 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CFK41_RS13475 8de3bb9e5e75f11afefa70fc49d63a2b 423 PRINTS PR00981 Seryl-tRNA synthetase signature 329 345 1.2E-29 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CFK41_RS13475 8de3bb9e5e75f11afefa70fc49d63a2b 423 PRINTS PR00981 Seryl-tRNA synthetase signature 347 363 1.2E-29 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CFK41_RS13475 8de3bb9e5e75f11afefa70fc49d63a2b 423 PRINTS PR00981 Seryl-tRNA synthetase signature 272 285 1.2E-29 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CFK41_RS13475 8de3bb9e5e75f11afefa70fc49d63a2b 423 PRINTS PR00981 Seryl-tRNA synthetase signature 260 272 1.2E-29 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CFK41_RS13475 8de3bb9e5e75f11afefa70fc49d63a2b 423 PRINTS PR00981 Seryl-tRNA synthetase signature 312 325 1.2E-29 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CFK41_RS13475 8de3bb9e5e75f11afefa70fc49d63a2b 423 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 105 5.9E-25 T 28-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 CFK41_RS13475 8de3bb9e5e75f11afefa70fc49d63a2b 423 SUPERFAMILY SSF46589 1 106 1.46E-22 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CFK41_RS13475 8de3bb9e5e75f11afefa70fc49d63a2b 423 Gene3D G3DSA:1.10.287.40 1 103 2.9E-24 T 28-03-2018 CFK41_RS13475 8de3bb9e5e75f11afefa70fc49d63a2b 423 SUPERFAMILY SSF55681 116 414 7.35E-83 T 28-03-2018 CFK41_RS13475 8de3bb9e5e75f11afefa70fc49d63a2b 423 Gene3D G3DSA:3.30.930.10 104 415 1.0E-78 T 28-03-2018 CFK41_RS17490 11de4beefca345e352bace021b2ad9b9 93 Pfam PF01809 Haemolytic domain 11 76 1.6E-25 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CFK41_RS17490 11de4beefca345e352bace021b2ad9b9 93 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 24 76 1.0E-13 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CFK41_RS17490 11de4beefca345e352bace021b2ad9b9 93 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 16 79 2.5E-26 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CFK41_RS17490 11de4beefca345e352bace021b2ad9b9 93 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 9 77 22.89 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CFK41_RS17490 11de4beefca345e352bace021b2ad9b9 93 SMART SM01234 9 76 5.2E-38 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CFK41_RS12405 8eba0074a58fa726cc9b57a1472cb653 387 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 65 369 1.5E-12 T 28-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CFK41_RS15290 c5f16a9ea8f762cb022a7719c1603966 113 SUPERFAMILY SSF141530 1 102 3.4E-27 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CFK41_RS15290 c5f16a9ea8f762cb022a7719c1603966 113 Gene3D G3DSA:2.40.33.40 1 110 8.6E-30 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CFK41_RS15290 c5f16a9ea8f762cb022a7719c1603966 113 Pfam PF03829 PTS system glucitol/sorbitol-specific IIA component 1 101 2.2E-28 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CFK41_RS15290 c5f16a9ea8f762cb022a7719c1603966 113 ProDom PD015842 PTS IIA COMPONENT GLUCITOL/SORBITOL-SPECIFIC SYSTEM ENZYME TRANSFERASE SYSTEM PHOSPHOTRANSFERASE EIIA 1 95 1.0E-24 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CFK41_RS08620 66ca8c3083e29b245dfcc4b3fac4181b 290 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 6 271 8.9E-75 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CFK41_RS08620 66ca8c3083e29b245dfcc4b3fac4181b 290 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 279 17.665 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CFK41_RS08620 66ca8c3083e29b245dfcc4b3fac4181b 290 Pfam PF02673 Bacitracin resistance protein BacA 6 273 3.7E-82 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CFK41_RS14785 563273f49661725c8e35889c3c279004 577 Gene3D G3DSA:3.40.50.300 387 550 4.0E-5 T 28-03-2018 CFK41_RS14785 563273f49661725c8e35889c3c279004 577 Gene3D G3DSA:3.40.50.10810 83 322 5.1E-17 T 28-03-2018 CFK41_RS14785 563273f49661725c8e35889c3c279004 577 SMART SM00487 102 279 1.8E-7 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CFK41_RS14785 563273f49661725c8e35889c3c279004 577 SUPERFAMILY SSF52540 178 269 3.44E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS14785 563273f49661725c8e35889c3c279004 577 SUPERFAMILY SSF52540 394 532 3.44E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS14785 563273f49661725c8e35889c3c279004 577 SUPERFAMILY SSF52540 105 251 2.41E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS04705 9945b054959f6e597288d6a56636113c 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 8.0E-8 T 28-03-2018 CFK41_RS04705 9945b054959f6e597288d6a56636113c 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.175 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04705 9945b054959f6e597288d6a56636113c 37 Pfam PF00444 Ribosomal protein L36 1 37 4.3E-19 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04705 9945b054959f6e597288d6a56636113c 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 3.3E-22 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04705 9945b054959f6e597288d6a56636113c 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04705 9945b054959f6e597288d6a56636113c 37 SUPERFAMILY SSF57840 1 37 3.79E-17 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS11000 ea8d21380c73b8eb9364f1879134e38d 537 Gene3D G3DSA:3.40.1800.10 398 462 3.0E-6 T 28-03-2018 CFK41_RS11000 ea8d21380c73b8eb9364f1879134e38d 537 Pfam PF01844 HNH endonuclease 429 458 5.9E-5 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CFK41_RS11000 ea8d21380c73b8eb9364f1879134e38d 537 SMART SM00507 406 456 3.0E-4 T 28-03-2018 IPR003615 HNH nuclease CFK41_RS11000 ea8d21380c73b8eb9364f1879134e38d 537 Pfam PF02720 Domain of unknown function (DUF222) 96 353 6.0E-15 T 28-03-2018 IPR003870 Domain of unknown function DUF222 CFK41_RS07210 6e8e38bf6b6b245c4a65fb3f4ba612ac 505 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 19 501 8.1E-135 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CFK41_RS07210 6e8e38bf6b6b245c4a65fb3f4ba612ac 505 SUPERFAMILY SSF55931 21 323 2.75E-103 T 28-03-2018 CFK41_RS07210 6e8e38bf6b6b245c4a65fb3f4ba612ac 505 Pfam PF02637 GatB domain 354 501 3.4E-41 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CFK41_RS07210 6e8e38bf6b6b245c4a65fb3f4ba612ac 505 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 18 502 34.013 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CFK41_RS07210 6e8e38bf6b6b245c4a65fb3f4ba612ac 505 SMART SM00845 354 501 5.8E-60 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CFK41_RS07210 6e8e38bf6b6b245c4a65fb3f4ba612ac 505 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 167 181 - T 28-03-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 CFK41_RS07210 6e8e38bf6b6b245c4a65fb3f4ba612ac 505 SUPERFAMILY SSF89095 353 501 1.83E-24 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CFK41_RS07210 6e8e38bf6b6b245c4a65fb3f4ba612ac 505 Gene3D G3DSA:1.10.10.410 441 502 5.1E-18 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CFK41_RS07210 6e8e38bf6b6b245c4a65fb3f4ba612ac 505 Pfam PF02934 GatB/GatE catalytic domain 22 316 9.1E-97 T 28-03-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 CFK41_RS09590 3da43f56c7257b6e3a2fad61aa1dc4fa 440 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 156 427 1.4E-69 T 28-03-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 CFK41_RS09590 3da43f56c7257b6e3a2fad61aa1dc4fa 440 SUPERFAMILY SSF101960 75 435 5.49E-84 T 28-03-2018 CFK41_RS09590 3da43f56c7257b6e3a2fad61aa1dc4fa 440 Pfam PF01458 Uncharacterized protein family (UPF0051) 189 410 1.0E-70 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CFK41_RS11390 0e7d43b48ba617388b877a6e1ba8b8da 549 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 92 113 - T 28-03-2018 IPR023765 Solute-binding protein family 5, conserved site CFK41_RS11390 0e7d43b48ba617388b877a6e1ba8b8da 549 PIRSF PIRSF002741 2 537 9.5E-71 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CFK41_RS11390 0e7d43b48ba617388b877a6e1ba8b8da 549 Gene3D G3DSA:3.40.190.10 210 319 6.2E-27 T 28-03-2018 CFK41_RS11390 0e7d43b48ba617388b877a6e1ba8b8da 549 Gene3D G3DSA:3.10.105.10 320 522 2.4E-40 T 28-03-2018 CFK41_RS11390 0e7d43b48ba617388b877a6e1ba8b8da 549 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 87 466 1.8E-62 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CFK41_RS11390 0e7d43b48ba617388b877a6e1ba8b8da 549 Gene3D G3DSA:3.90.76.10 55 209 1.2E-29 T 28-03-2018 CFK41_RS11390 0e7d43b48ba617388b877a6e1ba8b8da 549 SUPERFAMILY SSF53850 52 546 1.14E-98 T 28-03-2018 CFK41_RS11600 985f98d00ba211eeeec7f648858a8f58 522 Hamap MF_00900 GTPase HflX [hflX]. 126 495 47.037 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CFK41_RS11600 985f98d00ba211eeeec7f648858a8f58 522 Gene3D G3DSA:3.40.50.300 295 519 1.2E-32 T 28-03-2018 CFK41_RS11600 985f98d00ba211eeeec7f648858a8f58 522 PIRSF PIRSF006809 67 106 300.0 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CFK41_RS11600 985f98d00ba211eeeec7f648858a8f58 522 PIRSF PIRSF006809 98 522 6.4E-154 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CFK41_RS11600 985f98d00ba211eeeec7f648858a8f58 522 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 108 465 1.0E-130 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CFK41_RS11600 985f98d00ba211eeeec7f648858a8f58 522 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 307 327 2.2E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CFK41_RS11600 985f98d00ba211eeeec7f648858a8f58 522 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 374 392 2.2E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CFK41_RS11600 985f98d00ba211eeeec7f648858a8f58 522 Pfam PF01926 50S ribosome-binding GTPase 307 425 1.2E-19 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CFK41_RS11600 985f98d00ba211eeeec7f648858a8f58 522 Pfam PF16360 GTP-binding GTPase Middle Region 213 299 2.1E-29 T 28-03-2018 IPR032305 GTP-binding protein, middle domain CFK41_RS11600 985f98d00ba211eeeec7f648858a8f58 522 Pfam PF13167 GTP-binding GTPase N-terminal 123 211 3.5E-31 T 28-03-2018 IPR025121 GTPase HflX, N-terminal CFK41_RS11600 985f98d00ba211eeeec7f648858a8f58 522 SUPERFAMILY SSF52540 306 492 3.3E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS15695 fa9f16bc8db87860a1ec7c7b263ef3b8 480 Gene3D G3DSA:3.40.50.300 199 476 2.0E-69 T 28-03-2018 CFK41_RS15695 fa9f16bc8db87860a1ec7c7b263ef3b8 480 SUPERFAMILY SSF52540 215 464 3.2E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS15695 fa9f16bc8db87860a1ec7c7b263ef3b8 480 Pfam PF03796 DnaB-like helicase C terminal domain 217 471 1.2E-103 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CFK41_RS15695 fa9f16bc8db87860a1ec7c7b263ef3b8 480 SUPERFAMILY SSF48024 39 150 1.44E-36 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CFK41_RS15695 fa9f16bc8db87860a1ec7c7b263ef3b8 480 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 41 473 5.0E-163 T 28-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 CFK41_RS15695 fa9f16bc8db87860a1ec7c7b263ef3b8 480 Gene3D G3DSA:1.10.860.10 34 183 2.7E-51 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CFK41_RS15695 fa9f16bc8db87860a1ec7c7b263ef3b8 480 Pfam PF00772 DnaB-like helicase N terminal domain 41 142 1.0E-33 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CFK41_RS14330 dd2e61dc1d5812eb5b9829a85aeb383d 151 SUPERFAMILY SSF51905 57 130 5.33E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS14330 dd2e61dc1d5812eb5b9829a85aeb383d 151 Gene3D G3DSA:3.50.50.60 5 141 3.9E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS13385 aa2a8d8c9259f4671f53d5fc2708fde8 67 PRINTS PR00050 Cold shock protein signature 40 58 1.1E-14 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CFK41_RS13385 aa2a8d8c9259f4671f53d5fc2708fde8 67 PRINTS PR00050 Cold shock protein signature 4 19 1.1E-14 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CFK41_RS13385 aa2a8d8c9259f4671f53d5fc2708fde8 67 PRINTS PR00050 Cold shock protein signature 25 34 1.1E-14 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CFK41_RS13385 aa2a8d8c9259f4671f53d5fc2708fde8 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 1.2E-27 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CFK41_RS13385 aa2a8d8c9259f4671f53d5fc2708fde8 67 Gene3D G3DSA:2.40.50.140 1 67 8.6E-27 T 28-03-2018 CFK41_RS13385 aa2a8d8c9259f4671f53d5fc2708fde8 67 PIRSF PIRSF002599 1 67 7.8E-23 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CFK41_RS13385 aa2a8d8c9259f4671f53d5fc2708fde8 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 28-03-2018 IPR019844 Cold-shock conserved site CFK41_RS13385 aa2a8d8c9259f4671f53d5fc2708fde8 67 SUPERFAMILY SSF50249 1 65 1.78E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS13385 aa2a8d8c9259f4671f53d5fc2708fde8 67 SMART SM00357 3 67 3.9E-28 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CFK41_RS03405 5e6e1507b3064a5c01c7d7be7d75fc41 225 SUPERFAMILY SSF46785 146 224 3.22E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS03405 5e6e1507b3064a5c01c7d7be7d75fc41 225 SUPERFAMILY SSF51206 5 143 3.67E-36 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CFK41_RS03405 5e6e1507b3064a5c01c7d7be7d75fc41 225 SMART SM00100 11 129 3.1E-25 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CFK41_RS03405 5e6e1507b3064a5c01c7d7be7d75fc41 225 Pfam PF00027 Cyclic nucleotide-binding domain 31 116 4.5E-24 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CFK41_RS03405 5e6e1507b3064a5c01c7d7be7d75fc41 225 Gene3D G3DSA:2.60.120.10 3 138 1.5E-34 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CFK41_RS03405 5e6e1507b3064a5c01c7d7be7d75fc41 225 Gene3D G3DSA:1.10.10.10 139 225 4.6E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS03405 5e6e1507b3064a5c01c7d7be7d75fc41 225 SMART SM00419 168 216 1.7E-11 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CFK41_RS03405 5e6e1507b3064a5c01c7d7be7d75fc41 225 Pfam PF13545 Crp-like helix-turn-helix domain 149 222 2.8E-15 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CFK41_RS08105 9458c1e66e7110a8aff2224e47cde9c7 240 Pfam PF07729 FCD domain 93 222 7.2E-23 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS08105 9458c1e66e7110a8aff2224e47cde9c7 240 SUPERFAMILY SSF48008 88 229 9.15E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS08105 9458c1e66e7110a8aff2224e47cde9c7 240 SUPERFAMILY SSF46785 5 72 3.91E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS08105 9458c1e66e7110a8aff2224e47cde9c7 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 1.9E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS08105 9458c1e66e7110a8aff2224e47cde9c7 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 1.9E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS08105 9458c1e66e7110a8aff2224e47cde9c7 240 SMART SM00895 92 223 1.0E-18 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS08105 9458c1e66e7110a8aff2224e47cde9c7 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 68 5.4E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS08105 9458c1e66e7110a8aff2224e47cde9c7 240 SMART SM00345 9 68 6.8E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS08105 9458c1e66e7110a8aff2224e47cde9c7 240 Gene3D G3DSA:1.10.10.10 1 71 1.6E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS08105 9458c1e66e7110a8aff2224e47cde9c7 240 Gene3D G3DSA:1.20.120.530 84 234 1.4E-29 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS00815 8c33370e96a4952f2855cc27457d3554 137 PRINTS PR01438 Universal stress protein signature 105 127 2.2E-8 T 28-03-2018 IPR006015 Universal stress protein A CFK41_RS00815 8c33370e96a4952f2855cc27457d3554 137 PRINTS PR01438 Universal stress protein signature 1 17 2.2E-8 T 28-03-2018 IPR006015 Universal stress protein A CFK41_RS00815 8c33370e96a4952f2855cc27457d3554 137 PRINTS PR01438 Universal stress protein signature 87 99 2.2E-8 T 28-03-2018 IPR006015 Universal stress protein A CFK41_RS00815 8c33370e96a4952f2855cc27457d3554 137 Pfam PF00582 Universal stress protein family 2 127 6.9E-18 T 28-03-2018 IPR006016 UspA GO:0006950 CFK41_RS00815 8c33370e96a4952f2855cc27457d3554 137 SUPERFAMILY SSF52402 1 132 6.36E-23 T 28-03-2018 CFK41_RS00815 8c33370e96a4952f2855cc27457d3554 137 Gene3D G3DSA:3.40.50.620 1 131 1.2E-25 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS16555 c09faca0bdcb9b1cba4ac3bc9101dbc6 145 SUPERFAMILY SSF46785 22 138 9.26E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS16555 c09faca0bdcb9b1cba4ac3bc9101dbc6 145 Gene3D G3DSA:1.10.10.10 2 143 1.6E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS16555 c09faca0bdcb9b1cba4ac3bc9101dbc6 145 SMART SM00347 26 126 5.9E-19 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS16555 c09faca0bdcb9b1cba4ac3bc9101dbc6 145 Pfam PF01047 MarR family 37 90 7.3E-17 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS16555 c09faca0bdcb9b1cba4ac3bc9101dbc6 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 8.7E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS16555 c09faca0bdcb9b1cba4ac3bc9101dbc6 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 8.7E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS16555 c09faca0bdcb9b1cba4ac3bc9101dbc6 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 8.7E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS16555 c09faca0bdcb9b1cba4ac3bc9101dbc6 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 8.7E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS01275 7f3cae7d259c663e8759d68f8ee71bd1 700 SUPERFAMILY SSF48208 303 686 7.31E-31 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CFK41_RS01275 7f3cae7d259c663e8759d68f8ee71bd1 700 Gene3D G3DSA:2.70.98.50 12 277 2.8E-5 T 28-03-2018 CFK41_RS01275 7f3cae7d259c663e8759d68f8ee71bd1 700 Gene3D G3DSA:1.50.10.10 289 668 2.3E-41 T 28-03-2018 CFK41_RS16580 5332a6658377e376cafecdac58b683f4 263 SUPERFAMILY SSF46785 12 84 1.52E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS16580 5332a6658377e376cafecdac58b683f4 263 SUPERFAMILY SSF55781 86 252 1.11E-32 T 28-03-2018 IPR029016 GAF domain-like CFK41_RS16580 5332a6658377e376cafecdac58b683f4 263 Gene3D G3DSA:3.30.450.40 82 254 5.9E-35 T 28-03-2018 IPR029016 GAF domain-like CFK41_RS16580 5332a6658377e376cafecdac58b683f4 263 Pfam PF09339 IclR helix-turn-helix domain 14 65 3.8E-17 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CFK41_RS16580 5332a6658377e376cafecdac58b683f4 263 SMART SM00346 12 103 2.3E-15 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CFK41_RS16580 5332a6658377e376cafecdac58b683f4 263 Gene3D G3DSA:1.10.10.10 4 81 9.8E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS16580 5332a6658377e376cafecdac58b683f4 263 Pfam PF01614 Bacterial transcriptional regulator 130 247 7.9E-16 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CFK41_RS01095 0f00d4dab89c71276a737d8d612f1d1e 279 Gene3D G3DSA:3.40.50.720 1 225 1.1E-23 T 28-03-2018 CFK41_RS01095 0f00d4dab89c71276a737d8d612f1d1e 279 Pfam PF13460 NAD(P)H-binding 7 181 9.3E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS01095 0f00d4dab89c71276a737d8d612f1d1e 279 SUPERFAMILY SSF51735 2 252 5.95E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS08240 e2f078c02dabd313d1808d9b06808fc7 446 Gene3D G3DSA:1.20.1250.20 7 227 7.6E-23 T 28-03-2018 CFK41_RS08240 e2f078c02dabd313d1808d9b06808fc7 446 Gene3D G3DSA:1.20.1250.20 228 443 7.1E-25 T 28-03-2018 CFK41_RS08240 e2f078c02dabd313d1808d9b06808fc7 446 Pfam PF07690 Major Facilitator Superfamily 32 351 1.3E-24 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS08240 e2f078c02dabd313d1808d9b06808fc7 446 ProSitePatterns PS00217 Sugar transport proteins signature 2. 135 160 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CFK41_RS08240 e2f078c02dabd313d1808d9b06808fc7 446 SUPERFAMILY SSF103473 7 430 1.44E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS07515 9d3c8045ca0ab0e56985aae349c16307 942 Gene3D G3DSA:2.40.50.140 444 533 1.8E-26 T 28-03-2018 CFK41_RS07515 9d3c8045ca0ab0e56985aae349c16307 942 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 426 824 3.9E-151 T 28-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 CFK41_RS07515 9d3c8045ca0ab0e56985aae349c16307 942 Pfam PF10150 Ribonuclease E/G family 530 799 2.5E-103 T 28-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 CFK41_RS07515 9d3c8045ca0ab0e56985aae349c16307 942 SMART SM00316 449 528 3.6E-6 T 28-03-2018 IPR022967 RNA-binding domain, S1 CFK41_RS07515 9d3c8045ca0ab0e56985aae349c16307 942 SUPERFAMILY SSF50249 451 534 1.22E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS10555 5d86a7a1024f1ae2e5f600251a309b15 322 Pfam PF00588 SpoU rRNA Methylase family 169 310 2.1E-35 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CFK41_RS10555 5d86a7a1024f1ae2e5f600251a309b15 322 Gene3D G3DSA:3.40.1280.10 150 320 1.3E-44 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CFK41_RS10555 5d86a7a1024f1ae2e5f600251a309b15 322 SMART SM00967 76 152 3.0E-13 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CFK41_RS10555 5d86a7a1024f1ae2e5f600251a309b15 322 SUPERFAMILY SSF75217 140 313 5.17E-43 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CFK41_RS10555 5d86a7a1024f1ae2e5f600251a309b15 322 SUPERFAMILY SSF55315 70 149 6.83E-15 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CFK41_RS10555 5d86a7a1024f1ae2e5f600251a309b15 322 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 77 152 5.2E-16 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CFK41_RS10555 5d86a7a1024f1ae2e5f600251a309b15 322 Gene3D G3DSA:3.30.1330.30 65 148 4.9E-16 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CFK41_RS10555 5d86a7a1024f1ae2e5f600251a309b15 322 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 75 313 1.2E-67 T 28-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 CFK41_RS00145 f46c4901da411a9946e6ef62791f3a40 418 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 78 1.9E-19 T 28-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 CFK41_RS00145 f46c4901da411a9946e6ef62791f3a40 418 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 197 416 1.5E-47 T 28-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 CFK41_RS00605 8c0c0e7db5a7388ab2568c7a64df8c31 798 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 50 189 1.9E-19 T 28-03-2018 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CFK41_RS00605 8c0c0e7db5a7388ab2568c7a64df8c31 798 SUPERFAMILY SSF55545 48 191 1.44E-16 T 28-03-2018 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CFK41_RS00605 8c0c0e7db5a7388ab2568c7a64df8c31 798 Pfam PF00754 F5/8 type C domain 676 789 6.5E-15 T 28-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain CFK41_RS00605 8c0c0e7db5a7388ab2568c7a64df8c31 798 Gene3D G3DSA:2.60.120.260 661 793 3.4E-19 T 28-03-2018 IPR008979 Galactose-binding domain-like CFK41_RS00605 8c0c0e7db5a7388ab2568c7a64df8c31 798 Gene3D G3DSA:3.20.20.80 193 497 1.4E-102 T 28-03-2018 CFK41_RS00605 8c0c0e7db5a7388ab2568c7a64df8c31 798 Gene3D G3DSA:1.20.58.460 498 656 2.7E-23 T 28-03-2018 CFK41_RS00605 8c0c0e7db5a7388ab2568c7a64df8c31 798 Gene3D G3DSA:3.30.379.10 39 189 4.4E-17 T 28-03-2018 CFK41_RS00605 8c0c0e7db5a7388ab2568c7a64df8c31 798 SUPERFAMILY SSF51445 194 506 2.63E-92 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS00605 8c0c0e7db5a7388ab2568c7a64df8c31 798 Pfam PF07555 beta-N-acetylglucosaminidase 196 498 2.3E-100 T 28-03-2018 IPR011496 Beta-N-acetylglucosaminidase MetaCyc: PWY-7437 CFK41_RS00605 8c0c0e7db5a7388ab2568c7a64df8c31 798 SUPERFAMILY SSF49785 666 791 1.35E-18 T 28-03-2018 IPR008979 Galactose-binding domain-like CFK41_RS07850 3cfe3f66195bcb7b98668b47fe936a33 345 SUPERFAMILY SSF53822 59 322 4.93E-35 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS07850 3cfe3f66195bcb7b98668b47fe936a33 345 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 9.1E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS07850 3cfe3f66195bcb7b98668b47fe936a33 345 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 9.1E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS07850 3cfe3f66195bcb7b98668b47fe936a33 345 Gene3D G3DSA:3.40.50.2300 167 332 1.1E-28 T 28-03-2018 CFK41_RS07850 3cfe3f66195bcb7b98668b47fe936a33 345 Gene3D G3DSA:1.10.260.40 1 52 7.3E-25 T 28-03-2018 CFK41_RS07850 3cfe3f66195bcb7b98668b47fe936a33 345 SUPERFAMILY SSF47413 3 60 1.87E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS07850 3cfe3f66195bcb7b98668b47fe936a33 345 SMART SM00354 2 72 6.7E-25 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS07850 3cfe3f66195bcb7b98668b47fe936a33 345 Pfam PF13377 Periplasmic binding protein-like domain 180 330 1.6E-24 T 28-03-2018 CFK41_RS07850 3cfe3f66195bcb7b98668b47fe936a33 345 Gene3D G3DSA:3.40.50.2300 53 166 3.3E-16 T 28-03-2018 CFK41_RS07850 3cfe3f66195bcb7b98668b47fe936a33 345 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 28-03-2018 CFK41_RS07850 3cfe3f66195bcb7b98668b47fe936a33 345 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 6.9E-17 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS16085 1e576350b2259b8ad9f71eba40266bf2 334 Gene3D G3DSA:3.40.190.10 58 201 6.6E-24 T 28-03-2018 CFK41_RS16085 1e576350b2259b8ad9f71eba40266bf2 334 SMART SM00062 88 320 1.1E-23 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CFK41_RS16085 1e576350b2259b8ad9f71eba40266bf2 334 SUPERFAMILY SSF53850 78 317 2.92E-39 T 28-03-2018 CFK41_RS16085 1e576350b2259b8ad9f71eba40266bf2 334 Gene3D G3DSA:3.40.190.10 202 272 1.3E-8 T 28-03-2018 CFK41_RS16085 1e576350b2259b8ad9f71eba40266bf2 334 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 89 316 3.9E-37 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CFK41_RS08145 60ed6a6ca9ed9a907dabf55ee49bb1ff 375 Gene3D G3DSA:2.60.260.20 205 253 7.5E-10 T 28-03-2018 CFK41_RS08145 60ed6a6ca9ed9a907dabf55ee49bb1ff 375 PRINTS PR00625 DnaJ domain signature 6 24 1.4E-24 T 28-03-2018 IPR001623 DnaJ domain CFK41_RS08145 60ed6a6ca9ed9a907dabf55ee49bb1ff 375 PRINTS PR00625 DnaJ domain signature 40 60 1.4E-24 T 28-03-2018 IPR001623 DnaJ domain CFK41_RS08145 60ed6a6ca9ed9a907dabf55ee49bb1ff 375 PRINTS PR00625 DnaJ domain signature 60 79 1.4E-24 T 28-03-2018 IPR001623 DnaJ domain CFK41_RS08145 60ed6a6ca9ed9a907dabf55ee49bb1ff 375 PRINTS PR00625 DnaJ domain signature 24 39 1.4E-24 T 28-03-2018 IPR001623 DnaJ domain CFK41_RS08145 60ed6a6ca9ed9a907dabf55ee49bb1ff 375 Pfam PF00226 DnaJ domain 4 65 3.0E-26 T 28-03-2018 IPR001623 DnaJ domain CFK41_RS08145 60ed6a6ca9ed9a907dabf55ee49bb1ff 375 Pfam PF01556 DnaJ C terminal domain 118 332 1.9E-33 T 28-03-2018 IPR002939 Chaperone DnaJ, C-terminal CFK41_RS08145 60ed6a6ca9ed9a907dabf55ee49bb1ff 375 Gene3D G3DSA:2.10.230.10 139 204 8.6E-14 T 28-03-2018 CFK41_RS08145 60ed6a6ca9ed9a907dabf55ee49bb1ff 375 SUPERFAMILY SSF49493 185 260 4.19E-15 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CFK41_RS08145 60ed6a6ca9ed9a907dabf55ee49bb1ff 375 SUPERFAMILY SSF49493 108 133 4.19E-15 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CFK41_RS08145 60ed6a6ca9ed9a907dabf55ee49bb1ff 375 SUPERFAMILY SSF57938 129 208 1.18E-15 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CFK41_RS08145 60ed6a6ca9ed9a907dabf55ee49bb1ff 375 SUPERFAMILY SSF46565 3 97 4.19E-32 T 28-03-2018 IPR001623 DnaJ domain CFK41_RS08145 60ed6a6ca9ed9a907dabf55ee49bb1ff 375 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 375 35.319 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CFK41_RS08145 60ed6a6ca9ed9a907dabf55ee49bb1ff 375 Gene3D G3DSA:2.60.260.20 254 364 2.8E-24 T 28-03-2018 CFK41_RS08145 60ed6a6ca9ed9a907dabf55ee49bb1ff 375 Gene3D G3DSA:1.10.287.110 1 107 1.2E-31 T 28-03-2018 IPR001623 DnaJ domain CFK41_RS08145 60ed6a6ca9ed9a907dabf55ee49bb1ff 375 SMART SM00271 3 60 4.5E-30 T 28-03-2018 IPR001623 DnaJ domain CFK41_RS08145 60ed6a6ca9ed9a907dabf55ee49bb1ff 375 Pfam PF00684 DnaJ central domain 142 206 8.0E-11 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CFK41_RS08145 60ed6a6ca9ed9a907dabf55ee49bb1ff 375 SUPERFAMILY SSF49493 258 343 1.06E-17 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CFK41_RS03920 9d02c5add91e3a98fb69c3246f558680 148 Pfam PF01475 Ferric uptake regulator family 13 121 1.3E-19 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CFK41_RS03920 9d02c5add91e3a98fb69c3246f558680 148 SUPERFAMILY SSF46785 7 135 3.13E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS03920 9d02c5add91e3a98fb69c3246f558680 148 Gene3D G3DSA:1.10.10.10 6 90 1.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS02230 94e87cab465a38b516fc845f343f26db 372 SUPERFAMILY SSF55347 157 357 1.1E-57 T 28-03-2018 CFK41_RS02230 94e87cab465a38b516fc845f343f26db 372 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 30 371 1.1E-125 T 28-03-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CFK41_RS02230 94e87cab465a38b516fc845f343f26db 372 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 27 370 34.263 T 28-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CFK41_RS02230 94e87cab465a38b516fc845f343f26db 372 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 30 147 1.8E-27 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CFK41_RS02230 94e87cab465a38b516fc845f343f26db 372 Gene3D G3DSA:3.30.360.10 169 353 5.6E-63 T 28-03-2018 CFK41_RS02230 94e87cab465a38b516fc845f343f26db 372 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 167 356 1.8E-47 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CFK41_RS02230 94e87cab465a38b516fc845f343f26db 372 PIRSF PIRSF000148 27 372 2.8E-104 T 28-03-2018 CFK41_RS02230 94e87cab465a38b516fc845f343f26db 372 SMART SM00859 29 148 2.9E-34 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CFK41_RS02230 94e87cab465a38b516fc845f343f26db 372 SUPERFAMILY SSF51735 30 184 1.97E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS02230 94e87cab465a38b516fc845f343f26db 372 Gene3D G3DSA:3.40.50.720 26 168 2.5E-34 T 28-03-2018 CFK41_RS02230 94e87cab465a38b516fc845f343f26db 372 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 271 285 - T 28-03-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CFK41_RS06180 216aba900ce67de620fea6fea0802ac6 498 SUPERFAMILY SSF55729 347 494 1.06E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS06180 216aba900ce67de620fea6fea0802ac6 498 Pfam PF13302 Acetyltransferase (GNAT) domain 347 478 1.7E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS06180 216aba900ce67de620fea6fea0802ac6 498 Gene3D G3DSA:3.40.50.2000 130 324 3.6E-8 T 28-03-2018 CFK41_RS06180 216aba900ce67de620fea6fea0802ac6 498 SUPERFAMILY SSF53756 14 332 3.77E-7 T 28-03-2018 CFK41_RS06180 216aba900ce67de620fea6fea0802ac6 498 Gene3D G3DSA:3.40.630.30 326 495 6.4E-23 T 28-03-2018 CFK41_RS04235 d127ce0071db17c13ecf8cfa73253c6e 288 SUPERFAMILY SSF53335 25 234 6.35E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS04235 d127ce0071db17c13ecf8cfa73253c6e 288 Gene3D G3DSA:3.40.50.150 23 288 1.8E-36 T 28-03-2018 CFK41_RS04235 d127ce0071db17c13ecf8cfa73253c6e 288 Pfam PF13649 Methyltransferase domain 67 157 8.1E-19 T 28-03-2018 CFK41_RS11140 2f60d1844963e6ed0b0788e07d5b1ee3 316 SUPERFAMILY SSF82689 213 311 5.89E-9 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CFK41_RS11140 2f60d1844963e6ed0b0788e07d5b1ee3 316 Pfam PF00924 Mechanosensitive ion channel 105 304 1.1E-40 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CFK41_RS11140 2f60d1844963e6ed0b0788e07d5b1ee3 316 Gene3D G3DSA:3.30.70.100 212 310 1.7E-8 T 28-03-2018 CFK41_RS11140 2f60d1844963e6ed0b0788e07d5b1ee3 316 Gene3D G3DSA:2.30.30.60 165 211 1.2E-8 T 28-03-2018 CFK41_RS11140 2f60d1844963e6ed0b0788e07d5b1ee3 316 SUPERFAMILY SSF82861 88 146 6.02E-11 T 28-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CFK41_RS11140 2f60d1844963e6ed0b0788e07d5b1ee3 316 SUPERFAMILY SSF50182 148 205 3.6E-11 T 28-03-2018 IPR010920 LSM domain CFK41_RS14745 dbfa71adae6c2ebc28d829ea1e6ca951 298 Gene3D G3DSA:3.40.190.10 93 195 8.9E-32 T 28-03-2018 CFK41_RS14745 dbfa71adae6c2ebc28d829ea1e6ca951 298 SUPERFAMILY SSF53850 85 292 3.98E-23 T 28-03-2018 CFK41_RS14745 dbfa71adae6c2ebc28d829ea1e6ca951 298 Pfam PF03466 LysR substrate binding domain 88 289 5.9E-19 T 28-03-2018 IPR005119 LysR, substrate-binding CFK41_RS14745 dbfa71adae6c2ebc28d829ea1e6ca951 298 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 3 294 9.1E-87 T 28-03-2018 IPR017685 HTH-type transcriptional regulator ArgP CFK41_RS14745 dbfa71adae6c2ebc28d829ea1e6ca951 298 Gene3D G3DSA:1.10.10.10 1 88 7.6E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS14745 dbfa71adae6c2ebc28d829ea1e6ca951 298 SUPERFAMILY SSF46785 1 112 1.8E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS14745 dbfa71adae6c2ebc28d829ea1e6ca951 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 63 3.9E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CFK41_RS16575 2210e868d38d148908c7cf9a18ca43cf 470 Gene3D G3DSA:1.20.1250.20 269 468 4.4E-18 T 28-03-2018 CFK41_RS16575 2210e868d38d148908c7cf9a18ca43cf 470 Pfam PF07690 Major Facilitator Superfamily 39 407 4.7E-30 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS16575 2210e868d38d148908c7cf9a18ca43cf 470 Gene3D G3DSA:1.20.1250.20 31 244 2.0E-23 T 28-03-2018 CFK41_RS16575 2210e868d38d148908c7cf9a18ca43cf 470 SUPERFAMILY SSF103473 28 464 7.98E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS10210 7739f0be55d6a29208dc00998512f030 204 Gene3D G3DSA:3.40.50.1470 4 204 1.1E-67 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CFK41_RS10210 7739f0be55d6a29208dc00998512f030 204 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 10 192 32.318 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CFK41_RS10210 7739f0be55d6a29208dc00998512f030 204 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 121 131 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CFK41_RS10210 7739f0be55d6a29208dc00998512f030 204 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 23 36 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CFK41_RS10210 7739f0be55d6a29208dc00998512f030 204 Pfam PF01195 Peptidyl-tRNA hydrolase 12 198 2.2E-53 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CFK41_RS10210 7739f0be55d6a29208dc00998512f030 204 SUPERFAMILY SSF53178 11 199 1.57E-60 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CFK41_RS10210 7739f0be55d6a29208dc00998512f030 204 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 12 200 3.9E-52 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CFK41_RS10820 7d9d4f2129a46632e2537a04569a79ac 419 Gene3D G3DSA:3.30.470.20 118 378 2.4E-20 T 28-03-2018 CFK41_RS10820 7d9d4f2129a46632e2537a04569a79ac 419 SUPERFAMILY SSF56059 120 322 4.65E-19 T 28-03-2018 CFK41_RS09720 b1edce5752137ea536e25d9b478187c6 822 Gene3D G3DSA:3.90.199.10 50 301 2.0E-102 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS09720 b1edce5752137ea536e25d9b478187c6 822 Gene3D G3DSA:2.120.10.90 517 795 1.8E-54 T 28-03-2018 CFK41_RS09720 b1edce5752137ea536e25d9b478187c6 822 Gene3D G3DSA:1.10.268.10 360 502 9.6E-44 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS09720 b1edce5752137ea536e25d9b478187c6 822 SUPERFAMILY SSF56719 47 502 1.2E-159 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CFK41_RS09720 b1edce5752137ea536e25d9b478187c6 822 SMART SM00434 27 480 2.0E-237 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS09720 b1edce5752137ea536e25d9b478187c6 822 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 48 483 2.6E-142 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CFK41_RS09720 b1edce5752137ea536e25d9b478187c6 822 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 746 784 0.024 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CFK41_RS09720 b1edce5752137ea536e25d9b478187c6 822 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 677 722 1.1E-8 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CFK41_RS09720 b1edce5752137ea536e25d9b478187c6 822 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 569 587 1.8 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CFK41_RS09720 b1edce5752137ea536e25d9b478187c6 822 SUPERFAMILY SSF101904 519 787 3.14E-44 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CFK41_RS06000 0c576f7987f81501f01c7839453887ec 151 Gene3D G3DSA:1.20.1300.10 23 144 6.8E-23 T 28-03-2018 CFK41_RS06000 0c576f7987f81501f01c7839453887ec 151 SUPERFAMILY SSF81343 14 148 4.14E-32 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CFK41_RS06000 0c576f7987f81501f01c7839453887ec 151 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 29 131 3.8E-12 T 28-03-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 CFK41_RS06000 0c576f7987f81501f01c7839453887ec 151 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 17 122 1.3E-17 T 28-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CFK41_RS13800 5b251786420a6ae8719c4c16c4cd3f9b 376 Gene3D G3DSA:3.40.50.300 2 194 1.0E-7 T 28-03-2018 CFK41_RS13800 5b251786420a6ae8719c4c16c4cd3f9b 376 Gene3D G3DSA:1.10.10.10 263 375 3.2E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS13800 5b251786420a6ae8719c4c16c4cd3f9b 376 Pfam PF13191 AAA ATPase domain 3 152 3.9E-13 T 28-03-2018 CFK41_RS13800 5b251786420a6ae8719c4c16c4cd3f9b 376 SUPERFAMILY SSF52540 3 247 1.42E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS12460 e28c300b86855ca196a5390d2e97dce0 141 PIRSF PIRSF017349 8 140 6.4E-43 T 28-03-2018 IPR014487 Protein of unknown function DUF3151 CFK41_RS12460 e28c300b86855ca196a5390d2e97dce0 141 Pfam PF11349 Protein of unknown function (DUF3151) 15 138 7.0E-49 T 28-03-2018 IPR014487 Protein of unknown function DUF3151 CFK41_RS15235 983b652e167e4aa886deeff14bed0fce 244 Pfam PF01261 Xylose isomerase-like TIM barrel 70 191 5.6E-15 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS15235 983b652e167e4aa886deeff14bed0fce 244 Gene3D G3DSA:3.20.20.150 1 244 5.9E-32 T 28-03-2018 CFK41_RS15235 983b652e167e4aa886deeff14bed0fce 244 SUPERFAMILY SSF51658 5 243 2.13E-26 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS06965 74c8f07782dee4bfeb592618626433a8 304 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 91 102 - T 28-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 CFK41_RS06965 74c8f07782dee4bfeb592618626433a8 304 Gene3D G3DSA:3.30.230.10 6 171 3.0E-30 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CFK41_RS06965 74c8f07782dee4bfeb592618626433a8 304 Pfam PF00288 GHMP kinases N terminal domain 87 147 3.0E-9 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CFK41_RS06965 74c8f07782dee4bfeb592618626433a8 304 Hamap MF_00384 Homoserine kinase [thrB]. 8 289 27.245 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CFK41_RS06965 74c8f07782dee4bfeb592618626433a8 304 PRINTS PR00958 Homoserine kinase signature 15 30 3.3E-33 T 28-03-2018 CFK41_RS06965 74c8f07782dee4bfeb592618626433a8 304 PRINTS PR00958 Homoserine kinase signature 251 266 3.3E-33 T 28-03-2018 CFK41_RS06965 74c8f07782dee4bfeb592618626433a8 304 PRINTS PR00958 Homoserine kinase signature 98 113 3.3E-33 T 28-03-2018 CFK41_RS06965 74c8f07782dee4bfeb592618626433a8 304 PRINTS PR00958 Homoserine kinase signature 134 147 3.3E-33 T 28-03-2018 CFK41_RS06965 74c8f07782dee4bfeb592618626433a8 304 PRINTS PR00958 Homoserine kinase signature 174 191 3.3E-33 T 28-03-2018 CFK41_RS06965 74c8f07782dee4bfeb592618626433a8 304 SUPERFAMILY SSF54211 8 156 1.44E-26 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CFK41_RS06965 74c8f07782dee4bfeb592618626433a8 304 SUPERFAMILY SSF55060 171 273 1.62E-22 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CFK41_RS06965 74c8f07782dee4bfeb592618626433a8 304 TIGRFAM TIGR00191 thrB: homoserine kinase 8 271 2.4E-62 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CFK41_RS06965 74c8f07782dee4bfeb592618626433a8 304 Gene3D G3DSA:3.30.70.890 172 296 8.1E-22 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CFK41_RS06965 74c8f07782dee4bfeb592618626433a8 304 PIRSF PIRSF000676 4 292 1.2E-77 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CFK41_RS11865 4119cb7914d358957d3a20cae19a5dd0 513 SUPERFAMILY SSF52540 198 508 1.22E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11865 4119cb7914d358957d3a20cae19a5dd0 513 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 8 508 2.0E-136 T 28-03-2018 IPR004482 Mg chelatase-related protein CFK41_RS11865 4119cb7914d358957d3a20cae19a5dd0 513 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 143 3.7E-36 T 28-03-2018 CFK41_RS11865 4119cb7914d358957d3a20cae19a5dd0 513 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 412 508 1.8E-26 T 28-03-2018 IPR025158 Mg chelatase-related protein, C-terminal domain CFK41_RS11865 4119cb7914d358957d3a20cae19a5dd0 513 Pfam PF01078 Magnesium chelatase, subunit ChlI 199 402 1.8E-85 T 28-03-2018 IPR000523 Magnesium chelatase ChlI domain CFK41_RS11865 4119cb7914d358957d3a20cae19a5dd0 513 Gene3D G3DSA:3.40.50.300 192 467 1.4E-20 T 28-03-2018 CFK41_RS11865 4119cb7914d358957d3a20cae19a5dd0 513 Gene3D G3DSA:3.30.230.10 1 170 6.0E-37 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CFK41_RS11865 4119cb7914d358957d3a20cae19a5dd0 513 SUPERFAMILY SSF54211 2 165 3.79E-35 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CFK41_RS11865 4119cb7914d358957d3a20cae19a5dd0 513 SMART SM00382 219 403 7.2E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS05575 e4977a53d9a1293571bc4024517106ec 296 Pfam PF01925 Sulfite exporter TauE/SafE 10 292 6.0E-32 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CFK41_RS13690 4b25ead73d43b77cf4aa5d507adfa4f5 391 Gene3D G3DSA:2.20.25.10 10 50 7.4E-8 T 28-03-2018 CFK41_RS13690 4b25ead73d43b77cf4aa5d507adfa4f5 391 Gene3D G3DSA:3.90.820.10 78 152 0.011 T 28-03-2018 CFK41_RS17445 93abbc0a190a0e56bcfe3322e0f91028 417 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 4 206 36.074 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CFK41_RS17445 93abbc0a190a0e56bcfe3322e0f91028 417 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 208 402 36.608 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CFK41_RS17445 93abbc0a190a0e56bcfe3322e0f91028 417 PIRSF PIRSF001259 4 406 1.1E-151 T 28-03-2018 CFK41_RS17445 93abbc0a190a0e56bcfe3322e0f91028 417 Pfam PF00925 GTP cyclohydrolase II 215 375 4.6E-58 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CFK41_RS17445 93abbc0a190a0e56bcfe3322e0f91028 417 SUPERFAMILY SSF55821 5 205 9.84E-77 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CFK41_RS17445 93abbc0a190a0e56bcfe3322e0f91028 417 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 10 200 8.2E-80 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CFK41_RS17445 93abbc0a190a0e56bcfe3322e0f91028 417 SUPERFAMILY SSF142695 210 377 3.14E-53 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CFK41_RS17445 93abbc0a190a0e56bcfe3322e0f91028 417 Gene3D G3DSA:3.90.870.10 1 215 6.1E-90 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CFK41_RS17445 93abbc0a190a0e56bcfe3322e0f91028 417 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 7 202 9.8E-68 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CFK41_RS15780 a5811a5e5edbf0b39ad6b322b37a4068 405 Hamap MF_00985 2-amino-3-ketobutyrate coenzyme A ligase [kbl]. 2 403 51.918 T 28-03-2018 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 CFK41_RS15780 a5811a5e5edbf0b39ad6b322b37a4068 405 Pfam PF00155 Aminotransferase class I and II 47 395 8.3E-66 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CFK41_RS15780 a5811a5e5edbf0b39ad6b322b37a4068 405 Gene3D G3DSA:3.90.1150.10 297 405 4.5E-29 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS15780 a5811a5e5edbf0b39ad6b322b37a4068 405 SUPERFAMILY SSF53383 4 396 3.09E-112 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS15780 a5811a5e5edbf0b39ad6b322b37a4068 405 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 249 258 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CFK41_RS15780 a5811a5e5edbf0b39ad6b322b37a4068 405 Gene3D G3DSA:3.40.640.10 56 296 4.9E-51 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS15780 a5811a5e5edbf0b39ad6b322b37a4068 405 TIGRFAM TIGR01822 2am3keto_CoA: glycine C-acetyltransferase 5 397 2.4E-179 T 28-03-2018 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 CFK41_RS08125 e8357b4fad8fc09f7d20e735c1831b93 126 Pfam PF08818 Domain of unknown function (DU1801) 23 113 1.3E-10 T 28-03-2018 IPR014922 Domain of unknown function DUF1801 CFK41_RS08125 e8357b4fad8fc09f7d20e735c1831b93 126 SUPERFAMILY SSF159888 8 118 6.15E-23 T 28-03-2018 CFK41_RS03610 d1a1fd24c41f7f1dfafb17f11f3a3fa0 261 SMART SM00382 31 248 3.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS03610 d1a1fd24c41f7f1dfafb17f11f3a3fa0 261 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS03610 d1a1fd24c41f7f1dfafb17f11f3a3fa0 261 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 7 261 1.5E-110 T 28-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 CFK41_RS03610 d1a1fd24c41f7f1dfafb17f11f3a3fa0 261 Gene3D G3DSA:3.40.50.300 4 259 1.2E-56 T 28-03-2018 CFK41_RS03610 d1a1fd24c41f7f1dfafb17f11f3a3fa0 261 Pfam PF00005 ABC transporter 23 179 9.1E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS03610 d1a1fd24c41f7f1dfafb17f11f3a3fa0 261 SUPERFAMILY SSF52540 7 248 3.19E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS04890 0374879052c9104e65be1be0d4cc9931 426 Pfam PF02515 CoA-transferase family III 184 371 6.5E-44 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 CFK41_RS04890 0374879052c9104e65be1be0d4cc9931 426 Gene3D G3DSA:3.30.1540.10 71 152 5.9E-10 T 28-03-2018 CFK41_RS04890 0374879052c9104e65be1be0d4cc9931 426 Gene3D G3DSA:3.40.50.10540 178 396 4.8E-61 T 28-03-2018 IPR023606 CoA-transferase family III domain CFK41_RS04890 0374879052c9104e65be1be0d4cc9931 426 SUPERFAMILY SSF89796 180 382 8.11E-53 T 28-03-2018 IPR023606 CoA-transferase family III domain CFK41_RS04890 0374879052c9104e65be1be0d4cc9931 426 SUPERFAMILY SSF89796 36 178 1.7E-18 T 28-03-2018 IPR023606 CoA-transferase family III domain CFK41_RS17385 82a874c7dc7afd31d85606ec2605a7a7 234 Gene3D G3DSA:2.30.180.10 96 231 8.3E-26 T 28-03-2018 IPR000782 FAS1 domain CFK41_RS17385 82a874c7dc7afd31d85606ec2605a7a7 234 SMART SM00554 133 228 1.4E-28 T 28-03-2018 IPR000782 FAS1 domain CFK41_RS17385 82a874c7dc7afd31d85606ec2605a7a7 234 Pfam PF02469 Fasciclin domain 106 227 1.7E-24 T 28-03-2018 IPR000782 FAS1 domain CFK41_RS17385 82a874c7dc7afd31d85606ec2605a7a7 234 SUPERFAMILY SSF82153 89 228 1.44E-34 T 28-03-2018 IPR000782 FAS1 domain CFK41_RS11315 638349f7c64e2dc69d7bd5648acacab3 589 SUPERFAMILY SSF51905 10 182 7.77E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS11315 638349f7c64e2dc69d7bd5648acacab3 589 Gene3D G3DSA:3.50.50.60 1 589 1.1E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS11315 638349f7c64e2dc69d7bd5648acacab3 589 Pfam PF13454 FAD-NAD(P)-binding 12 174 1.2E-36 T 28-03-2018 CFK41_RS06615 22bc14ce06a9f3ff24fb88e8c3936e3c 211 Pfam PF09438 Domain of unknown function (DUF2017) 8 210 1.9E-42 T 28-03-2018 IPR018561 Domain of unknown function DUF2017 CFK41_RS13860 a90135365765d2a72583ecf88784c78b 211 SUPERFAMILY SSF52540 17 209 3.91E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS13860 a90135365765d2a72583ecf88784c78b 211 Gene3D G3DSA:3.40.50.300 22 211 2.2E-33 T 28-03-2018 CFK41_RS07975 dae7060ec0145a4d1e68c690946a7ee4 378 SUPERFAMILY SSF51905 10 371 1.64E-33 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS07975 dae7060ec0145a4d1e68c690946a7ee4 378 Gene3D G3DSA:3.50.50.60 201 367 5.9E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS07975 dae7060ec0145a4d1e68c690946a7ee4 378 Gene3D G3DSA:3.50.50.60 7 200 1.3E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS07975 dae7060ec0145a4d1e68c690946a7ee4 378 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 186 204 6.7E-6 T 28-03-2018 CFK41_RS07975 dae7060ec0145a4d1e68c690946a7ee4 378 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 14 33 6.7E-6 T 28-03-2018 CFK41_RS07975 dae7060ec0145a4d1e68c690946a7ee4 378 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 13 339 3.5E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS07975 dae7060ec0145a4d1e68c690946a7ee4 378 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 13 35 6.0E-9 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CFK41_RS07975 dae7060ec0145a4d1e68c690946a7ee4 378 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 182 206 6.0E-9 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CFK41_RS13825 44ae7344e0f192a6e6e92224239e5e92 303 Gene3D G3DSA:3.40.1190.20 1 303 3.9E-58 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS13825 44ae7344e0f192a6e6e92224239e5e92 303 Pfam PF00294 pfkB family carbohydrate kinase 6 293 2.8E-42 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CFK41_RS13825 44ae7344e0f192a6e6e92224239e5e92 303 SUPERFAMILY SSF53613 1 297 4.68E-57 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS17125 63b90d9a5964371b82cf4d0c2f9f36c2 309 SUPERFAMILY SSF51658 34 301 1.16E-38 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS17125 63b90d9a5964371b82cf4d0c2f9f36c2 309 Gene3D G3DSA:3.20.20.150 2 304 3.3E-44 T 28-03-2018 CFK41_RS17125 63b90d9a5964371b82cf4d0c2f9f36c2 309 Pfam PF01261 Xylose isomerase-like TIM barrel 38 238 2.9E-24 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS04765 2082e40abd771faf80c803024ad56c57 315 Pfam PF04198 Putative sugar-binding domain 69 311 3.2E-38 T 28-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 CFK41_RS04765 2082e40abd771faf80c803024ad56c57 315 SUPERFAMILY SSF88659 7 53 1.44E-5 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS04765 2082e40abd771faf80c803024ad56c57 315 SUPERFAMILY SSF100950 63 311 2.85E-38 T 28-03-2018 CFK41_RS04765 2082e40abd771faf80c803024ad56c57 315 Pfam PF04545 Sigma-70, region 4 7 52 1.6E-5 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CFK41_RS04765 2082e40abd771faf80c803024ad56c57 315 Gene3D G3DSA:3.40.50.1360 59 315 6.0E-22 T 28-03-2018 CFK41_RS04765 2082e40abd771faf80c803024ad56c57 315 Gene3D G3DSA:1.10.10.60 7 58 2.9E-13 T 28-03-2018 CFK41_RS08645 e11b42f47a39760b583c69cd58531e72 525 TIGRFAM TIGR03689 pup_AAA: proteasome ATPase 5 498 6.7E-201 T 28-03-2018 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 CFK41_RS08645 e11b42f47a39760b583c69cd58531e72 525 SMART SM00382 215 373 2.7E-20 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS08645 e11b42f47a39760b583c69cd58531e72 525 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 219 370 7.7E-46 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CFK41_RS08645 e11b42f47a39760b583c69cd58531e72 525 Pfam PF16450 Proteasomal ATPase OB/ID domain 48 176 3.2E-38 T 28-03-2018 IPR032501 Proteasomal ATPase, OB/ID domain CFK41_RS08645 e11b42f47a39760b583c69cd58531e72 525 Gene3D G3DSA:3.40.50.300 152 406 1.9E-53 T 28-03-2018 CFK41_RS08645 e11b42f47a39760b583c69cd58531e72 525 ProSitePatterns PS00674 AAA-protein family signature. 341 359 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CFK41_RS08645 e11b42f47a39760b583c69cd58531e72 525 SUPERFAMILY SSF52540 177 475 3.94E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS08645 e11b42f47a39760b583c69cd58531e72 525 Hamap MF_02112 Proteasome-associated ATPase [mpa]. 5 510 46.754 T 28-03-2018 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 CFK41_RS15900 aa827e848d06ea9d69a0848b3982fb22 439 Pfam PF01435 Peptidase family M48 147 236 9.7E-15 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CFK41_RS15900 aa827e848d06ea9d69a0848b3982fb22 439 Gene3D G3DSA:3.30.2010.10 137 220 5.6E-13 T 28-03-2018 CFK41_RS16710 661742533452d6d8388a5607210ce205 326 Gene3D G3DSA:3.20.20.30 8 325 2.4E-72 T 28-03-2018 CFK41_RS16710 661742533452d6d8388a5607210ce205 326 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 5 323 5.2E-120 T 28-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 CFK41_RS16710 661742533452d6d8388a5607210ce205 326 Pfam PF00296 Luciferase-like monooxygenase 15 299 3.4E-39 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CFK41_RS16710 661742533452d6d8388a5607210ce205 326 SUPERFAMILY SSF51679 4 322 3.4E-75 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CFK41_RS03910 c19fb21187016c59bd7047f0c65b64b5 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.0E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03910 c19fb21187016c59bd7047f0c65b64b5 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 1.0E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03910 c19fb21187016c59bd7047f0c65b64b5 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.0E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03910 c19fb21187016c59bd7047f0c65b64b5 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.0E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03910 c19fb21187016c59bd7047f0c65b64b5 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.0E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03910 c19fb21187016c59bd7047f0c65b64b5 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.0E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03910 c19fb21187016c59bd7047f0c65b64b5 241 Gene3D G3DSA:3.40.50.720 4 237 3.3E-50 T 28-03-2018 CFK41_RS03910 c19fb21187016c59bd7047f0c65b64b5 241 Pfam PF00106 short chain dehydrogenase 5 193 2.2E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03910 c19fb21187016c59bd7047f0c65b64b5 241 SUPERFAMILY SSF51735 2 228 2.41E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS04170 24616edb8ef4c1754b70e37214f07412 406 Pfam PF07730 Histidine kinase 194 259 1.3E-19 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CFK41_RS04170 24616edb8ef4c1754b70e37214f07412 406 SUPERFAMILY SSF55874 279 399 4.18E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS04170 24616edb8ef4c1754b70e37214f07412 406 Gene3D G3DSA:3.30.565.10 262 406 3.6E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS14395 1618df8f17c5c2fae68e8e09379e3a60 577 Pfam PF09848 Uncharacterized conserved protein (DUF2075) 183 561 8.3E-69 T 28-03-2018 IPR018647 Domain of unknown function DUF2075 CFK41_RS14395 1618df8f17c5c2fae68e8e09379e3a60 577 SUPERFAMILY SSF52540 105 293 2.31E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS14395 1618df8f17c5c2fae68e8e09379e3a60 577 SUPERFAMILY SSF52540 322 364 2.31E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS14395 1618df8f17c5c2fae68e8e09379e3a60 577 Gene3D G3DSA:3.40.1440.10 15 149 2.4E-5 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CFK41_RS14395 1618df8f17c5c2fae68e8e09379e3a60 577 Gene3D G3DSA:3.40.50.300 150 390 1.3E-12 T 28-03-2018 CFK41_RS03355 1347fd1ab37a85f73baca86b5cf42911 201 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 93 178 1.1E-15 T 28-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain CFK41_RS04755 28f01734985ee0abd062d6d77188441a 468 Pfam PF07690 Major Facilitator Superfamily 50 387 4.3E-15 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS04755 28f01734985ee0abd062d6d77188441a 468 Gene3D G3DSA:1.20.1250.20 264 455 5.4E-16 T 28-03-2018 CFK41_RS04755 28f01734985ee0abd062d6d77188441a 468 Gene3D G3DSA:1.20.1250.20 37 263 2.3E-14 T 28-03-2018 CFK41_RS04755 28f01734985ee0abd062d6d77188441a 468 TIGRFAM TIGR00885 fucP: L-fucose:H+ symporter permease 45 450 1.7E-95 T 28-03-2018 IPR005275 L-fucose permease FucP GO:0015150|GO:0015756 CFK41_RS04755 28f01734985ee0abd062d6d77188441a 468 SUPERFAMILY SSF103473 31 457 4.32E-34 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS00010 91ba352ca14d1ec06885b3e55b66b77a 184 Gene3D G3DSA:3.40.50.880 1 184 1.0E-44 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS00010 91ba352ca14d1ec06885b3e55b66b77a 184 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 16 183 2.8E-46 T 28-03-2018 IPR006286 Peptidase C56, PfpI CFK41_RS00010 91ba352ca14d1ec06885b3e55b66b77a 184 Pfam PF01965 DJ-1/PfpI family 10 181 1.6E-46 T 28-03-2018 IPR002818 DJ-1/PfpI CFK41_RS00010 91ba352ca14d1ec06885b3e55b66b77a 184 SUPERFAMILY SSF52317 8 183 8.28E-43 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS01215 6ab0c671ad104cc386592c1cae5b817b 574 Gene3D G3DSA:2.40.100.10 94 239 1.9E-46 T 28-03-2018 IPR029000 Cyclophilin-like domain CFK41_RS01215 6ab0c671ad104cc386592c1cae5b817b 574 SMART SM00797 289 574 5.9E-59 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CFK41_RS01215 6ab0c671ad104cc386592c1cae5b817b 574 SUPERFAMILY SSF50891 462 573 5.31E-10 T 28-03-2018 IPR029000 Cyclophilin-like domain CFK41_RS01215 6ab0c671ad104cc386592c1cae5b817b 574 SMART SM00796 18 223 1.7E-61 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CFK41_RS01215 6ab0c671ad104cc386592c1cae5b817b 574 Gene3D G3DSA:3.30.1360.40 18 92 1.4E-9 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CFK41_RS01215 6ab0c671ad104cc386592c1cae5b817b 574 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 20 223 2.6E-47 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CFK41_RS01215 6ab0c671ad104cc386592c1cae5b817b 574 SUPERFAMILY SSF50891 97 235 2.01E-32 T 28-03-2018 IPR029000 Cyclophilin-like domain CFK41_RS01215 6ab0c671ad104cc386592c1cae5b817b 574 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 291 571 2.2E-65 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CFK41_RS01215 6ab0c671ad104cc386592c1cae5b817b 574 SUPERFAMILY SSF160467 21 82 5.36E-5 T 28-03-2018 CFK41_RS15615 fd5cdccba873871d6e7cddf07f640f52 212 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 210 1.6E-74 T 28-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CFK41_RS15615 fd5cdccba873871d6e7cddf07f640f52 212 Gene3D G3DSA:3.40.50.2020 1 209 1.9E-62 T 28-03-2018 CFK41_RS15615 fd5cdccba873871d6e7cddf07f640f52 212 SUPERFAMILY SSF53271 3 209 1.21E-61 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CFK41_RS15615 fd5cdccba873871d6e7cddf07f640f52 212 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 211 41.605 T 28-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CFK41_RS15615 fd5cdccba873871d6e7cddf07f640f52 212 Pfam PF14681 Uracil phosphoribosyltransferase 7 209 9.7E-64 T 28-03-2018 CFK41_RS11905 00acfc4bbb4dae2db8ab67e8b028a2b6 194 SUPERFAMILY SSF50346 101 170 1.28E-16 T 28-03-2018 IPR011033 PRC-barrel-like CFK41_RS11905 00acfc4bbb4dae2db8ab67e8b028a2b6 194 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 6 170 2.6E-38 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CFK41_RS11905 00acfc4bbb4dae2db8ab67e8b028a2b6 194 Gene3D G3DSA:2.30.30.240 97 166 5.6E-20 T 28-03-2018 CFK41_RS11905 00acfc4bbb4dae2db8ab67e8b028a2b6 194 SUPERFAMILY SSF50447 6 89 6.0E-16 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CFK41_RS11905 00acfc4bbb4dae2db8ab67e8b028a2b6 194 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 5 171 21.448 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CFK41_RS11905 00acfc4bbb4dae2db8ab67e8b028a2b6 194 Pfam PF01782 RimM N-terminal domain 8 89 3.2E-21 T 28-03-2018 IPR002676 RimM protein GO:0006364 CFK41_RS11905 00acfc4bbb4dae2db8ab67e8b028a2b6 194 Pfam PF05239 PRC-barrel domain 102 170 1.5E-6 T 28-03-2018 IPR027275 PRC-barrel domain CFK41_RS11905 00acfc4bbb4dae2db8ab67e8b028a2b6 194 Gene3D G3DSA:2.40.30.60 6 92 7.7E-22 T 28-03-2018 IPR002676 RimM protein GO:0006364 CFK41_RS08700 5704755857737799f3bebf79566c6c21 235 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 24 208 3.6E-15 T 28-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 CFK41_RS08700 5704755857737799f3bebf79566c6c21 235 Pfam PF04973 Nicotinamide mononucleotide transporter 22 208 1.3E-49 T 28-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 CFK41_RS01100 39cccc62d0e791df99dc65b12f3c4b7c 162 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 15 157 3.0E-5 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CFK41_RS01100 39cccc62d0e791df99dc65b12f3c4b7c 162 Gene3D G3DSA:3.30.530.20 1 162 3.3E-22 T 28-03-2018 IPR023393 START-like domain CFK41_RS01100 39cccc62d0e791df99dc65b12f3c4b7c 162 SUPERFAMILY SSF55961 4 159 1.2E-19 T 28-03-2018 CFK41_RS03025 7c4883a308cc16eea4c0bee52b04cb63 243 Pfam PF03734 L,D-transpeptidase catalytic domain 125 220 5.2E-9 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CFK41_RS03025 7c4883a308cc16eea4c0bee52b04cb63 243 SUPERFAMILY SSF141523 124 228 1.83E-11 T 28-03-2018 CFK41_RS03025 7c4883a308cc16eea4c0bee52b04cb63 243 Pfam PF01471 Putative peptidoglycan binding domain 52 108 1.2E-13 T 28-03-2018 IPR002477 Peptidoglycan binding-like CFK41_RS03025 7c4883a308cc16eea4c0bee52b04cb63 243 Gene3D G3DSA:2.40.440.10 115 243 1.1E-13 T 28-03-2018 CFK41_RS03025 7c4883a308cc16eea4c0bee52b04cb63 243 SUPERFAMILY SSF47090 44 108 3.4E-16 T 28-03-2018 IPR002477 Peptidoglycan binding-like CFK41_RS03025 7c4883a308cc16eea4c0bee52b04cb63 243 Gene3D G3DSA:1.10.101.10 42 113 2.3E-20 T 28-03-2018 IPR002477 Peptidoglycan binding-like CFK41_RS05290 903bb8e5b438cd78cfc8e6cb6e6e0721 224 SUPERFAMILY SSF161098 13 206 6.17E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS05290 903bb8e5b438cd78cfc8e6cb6e6e0721 224 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 114 2.1E-12 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CFK41_RS05290 903bb8e5b438cd78cfc8e6cb6e6e0721 224 Gene3D G3DSA:1.10.3720.10 1 223 6.9E-29 T 28-03-2018 CFK41_RS05290 903bb8e5b438cd78cfc8e6cb6e6e0721 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 218 4.9E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS06665 1ea4088a7acbd5e9ca4c9d8fcf3f0fb0 143 Pfam PF02810 SEC-C motif 12 28 1.1E-6 T 28-03-2018 IPR004027 SEC-C motif CFK41_RS06665 1ea4088a7acbd5e9ca4c9d8fcf3f0fb0 143 SUPERFAMILY SSF54427 34 138 5.06E-31 T 28-03-2018 IPR032710 NTF2-like domain CFK41_RS06665 1ea4088a7acbd5e9ca4c9d8fcf3f0fb0 143 SUPERFAMILY SSF103642 11 29 9.97E-5 T 28-03-2018 CFK41_RS06665 1ea4088a7acbd5e9ca4c9d8fcf3f0fb0 143 Gene3D G3DSA:3.10.450.50 12 140 1.4E-42 T 28-03-2018 CFK41_RS17635 d64283af381605e3ab7bce7154a55eb4 408 Pfam PF00107 Zinc-binding dehydrogenase 206 273 7.7E-8 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CFK41_RS17635 d64283af381605e3ab7bce7154a55eb4 408 Gene3D G3DSA:3.90.180.10 5 192 6.5E-36 T 28-03-2018 CFK41_RS17635 d64283af381605e3ab7bce7154a55eb4 408 Gene3D G3DSA:3.40.50.720 193 344 8.2E-21 T 28-03-2018 CFK41_RS17635 d64283af381605e3ab7bce7154a55eb4 408 SUPERFAMILY SSF50129 4 195 2.76E-57 T 28-03-2018 IPR011032 GroES-like CFK41_RS17635 d64283af381605e3ab7bce7154a55eb4 408 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 44 153 6.4E-26 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CFK41_RS17635 d64283af381605e3ab7bce7154a55eb4 408 SUPERFAMILY SSF51735 172 361 3.7E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS17635 d64283af381605e3ab7bce7154a55eb4 408 TIGRFAM TIGR02819 fdhA_non_GSH: formaldehyde dehydrogenase, glutathione-independent 2 401 3.8E-216 T 28-03-2018 IPR014184 Formaldehyde dehydrogenase, glutathione-independent GO:0016491|GO:0055114 CFK41_RS17635 d64283af381605e3ab7bce7154a55eb4 408 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 76 90 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CFK41_RS05505 6fcae3fddbea1a49eb2716efb24724a5 402 Gene3D G3DSA:1.20.1250.20 201 398 4.6E-15 T 28-03-2018 CFK41_RS05505 6fcae3fddbea1a49eb2716efb24724a5 402 Pfam PF07690 Major Facilitator Superfamily 39 352 1.1E-17 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS05505 6fcae3fddbea1a49eb2716efb24724a5 402 SUPERFAMILY SSF103473 23 391 6.41E-36 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS05505 6fcae3fddbea1a49eb2716efb24724a5 402 ProSitePatterns PS00216 Sugar transport proteins signature 1. 64 79 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CFK41_RS05505 6fcae3fddbea1a49eb2716efb24724a5 402 Gene3D G3DSA:1.20.1250.20 17 200 1.3E-16 T 28-03-2018 CFK41_RS00345 9cd737b2b905af8347a5865a2df80166 295 Pfam PF01297 Zinc-uptake complex component A periplasmic 26 286 5.2E-72 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CFK41_RS00345 9cd737b2b905af8347a5865a2df80166 295 Gene3D G3DSA:3.40.50.1980 167 289 2.3E-34 T 28-03-2018 CFK41_RS00345 9cd737b2b905af8347a5865a2df80166 295 SUPERFAMILY SSF53807 7 289 1.18E-81 T 28-03-2018 CFK41_RS00345 9cd737b2b905af8347a5865a2df80166 295 PRINTS PR00690 Adhesin family signature 228 246 1.6E-39 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CFK41_RS00345 9cd737b2b905af8347a5865a2df80166 295 PRINTS PR00690 Adhesin family signature 67 84 1.6E-39 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CFK41_RS00345 9cd737b2b905af8347a5865a2df80166 295 PRINTS PR00690 Adhesin family signature 23 41 1.6E-39 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CFK41_RS00345 9cd737b2b905af8347a5865a2df80166 295 PRINTS PR00690 Adhesin family signature 254 273 1.6E-39 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CFK41_RS00345 9cd737b2b905af8347a5865a2df80166 295 PRINTS PR00690 Adhesin family signature 175 196 1.6E-39 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CFK41_RS00345 9cd737b2b905af8347a5865a2df80166 295 PRINTS PR00690 Adhesin family signature 54 67 1.6E-39 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CFK41_RS00345 9cd737b2b905af8347a5865a2df80166 295 Gene3D G3DSA:3.40.50.1980 22 166 6.5E-42 T 28-03-2018 CFK41_RS00345 9cd737b2b905af8347a5865a2df80166 295 PRINTS PR00691 Adhesin B signature 246 264 2.3E-24 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CFK41_RS00345 9cd737b2b905af8347a5865a2df80166 295 PRINTS PR00691 Adhesin B signature 201 219 2.3E-24 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CFK41_RS00345 9cd737b2b905af8347a5865a2df80166 295 PRINTS PR00691 Adhesin B signature 175 192 2.3E-24 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CFK41_RS00345 9cd737b2b905af8347a5865a2df80166 295 PRINTS PR00691 Adhesin B signature 23 44 2.3E-24 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CFK41_RS00345 9cd737b2b905af8347a5865a2df80166 295 PRINTS PR00691 Adhesin B signature 267 285 2.3E-24 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CFK41_RS00345 9cd737b2b905af8347a5865a2df80166 295 PRINTS PR00691 Adhesin B signature 48 66 2.3E-24 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CFK41_RS00345 9cd737b2b905af8347a5865a2df80166 295 PRINTS PR00691 Adhesin B signature 224 241 2.3E-24 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CFK41_RS07925 f74129cced8dc82e021969bf62b235f6 567 Pfam PF00999 Sodium/hydrogen exchanger family 9 443 2.2E-51 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CFK41_RS12350 c3fa6a5d4700d7cfc541dd95088c7c69 276 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 257 1.3E-28 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS12350 c3fa6a5d4700d7cfc541dd95088c7c69 276 SUPERFAMILY SSF56784 5 273 1.51E-36 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS12350 c3fa6a5d4700d7cfc541dd95088c7c69 276 Gene3D G3DSA:3.40.50.1000 2 275 3.3E-24 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS09175 95e130f834d442610675271f9734ca65 290 SUPERFAMILY SSF52540 35 286 4.44E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS09175 95e130f834d442610675271f9734ca65 290 Pfam PF13614 AAA domain 36 211 1.6E-61 T 28-03-2018 IPR025669 AAA domain CFK41_RS09175 95e130f834d442610675271f9734ca65 290 Gene3D G3DSA:3.40.50.300 19 290 1.0E-61 T 28-03-2018 CFK41_RS16520 4005bf2dac70b6a705032f0cfcfa1ebf 466 Pfam PF02447 GntP family permease 18 459 4.4E-124 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CFK41_RS16520 4005bf2dac70b6a705032f0cfcfa1ebf 466 PIRSF PIRSF002746 11 464 1.2E-146 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CFK41_RS16520 4005bf2dac70b6a705032f0cfcfa1ebf 466 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 18 462 4.1E-110 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CFK41_RS03500 414972cb1eaf2f8a8c9fc4244b4fe460 413 TIGRFAM TIGR03819 heli_sec_ATPase: helicase/secretion neighborhood ATPase 16 349 2.7E-129 T 28-03-2018 IPR022399 Helicase/secretion neighbourhood ATPase CFK41_RS03500 414972cb1eaf2f8a8c9fc4244b4fe460 413 Pfam PF00437 Type II/IV secretion system protein 72 339 9.4E-65 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CFK41_RS03500 414972cb1eaf2f8a8c9fc4244b4fe460 413 Gene3D G3DSA:3.40.50.300 167 339 1.3E-11 T 28-03-2018 CFK41_RS03500 414972cb1eaf2f8a8c9fc4244b4fe460 413 SUPERFAMILY SSF52540 52 344 6.04E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS03500 414972cb1eaf2f8a8c9fc4244b4fe460 413 Gene3D G3DSA:3.30.450.90 61 163 2.8E-23 T 28-03-2018 CFK41_RS08730 c84517e7812b05069bba9b681dd930e5 108 Pfam PF02416 mttA/Hcf106 family 7 53 2.5E-15 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 CFK41_RS08730 c84517e7812b05069bba9b681dd930e5 108 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 3 71 15.895 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CFK41_RS07260 885a068d98a37668beb9b2a775e901cd 363 Pfam PF01063 Amino-transferase class IV 74 318 3.3E-35 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CFK41_RS07260 885a068d98a37668beb9b2a775e901cd 363 PIRSF PIRSF006468 4 363 1.8E-127 T 28-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 CFK41_RS07260 885a068d98a37668beb9b2a775e901cd 363 Gene3D G3DSA:3.30.470.10 1 180 1.2E-64 T 28-03-2018 CFK41_RS07260 885a068d98a37668beb9b2a775e901cd 363 SUPERFAMILY SSF56752 6 359 5.76E-109 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CFK41_RS07260 885a068d98a37668beb9b2a775e901cd 363 ProSitePatterns PS00770 Aminotransferases class-IV signature. 238 268 - T 28-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CFK41_RS07260 885a068d98a37668beb9b2a775e901cd 363 Gene3D G3DSA:3.20.10.10 181 358 1.1E-47 T 28-03-2018 CFK41_RS07260 885a068d98a37668beb9b2a775e901cd 363 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 48 361 6.4E-126 T 28-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 CFK41_RS10125 d98f20a54f3c33ff95bcae2ff4569be1 338 SUPERFAMILY SSF56784 14 265 2.76E-59 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS10125 d98f20a54f3c33ff95bcae2ff4569be1 338 Pfam PF13242 HAD-hyrolase-like 192 264 1.9E-20 T 28-03-2018 CFK41_RS10125 d98f20a54f3c33ff95bcae2ff4569be1 338 Gene3D G3DSA:3.40.50.1000 109 192 8.3E-25 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS10125 d98f20a54f3c33ff95bcae2ff4569be1 338 Gene3D G3DSA:3.40.50.1000 13 108 1.3E-9 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS10125 d98f20a54f3c33ff95bcae2ff4569be1 338 PIRSF PIRSF000915 1 270 4.2E-64 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CFK41_RS10125 d98f20a54f3c33ff95bcae2ff4569be1 338 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 17 239 1.1E-38 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CFK41_RS10125 d98f20a54f3c33ff95bcae2ff4569be1 338 Pfam PF13344 Haloacid dehalogenase-like hydrolase 16 116 3.7E-25 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CFK41_RS10715 077854439b6b9d8b68c941d2e70bf86d 242 Pfam PF01048 Phosphorylase superfamily 15 222 1.1E-35 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CFK41_RS10715 077854439b6b9d8b68c941d2e70bf86d 242 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 61 76 - T 28-03-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 CFK41_RS10715 077854439b6b9d8b68c941d2e70bf86d 242 Gene3D G3DSA:3.40.50.1580 8 235 1.7E-49 T 28-03-2018 CFK41_RS10715 077854439b6b9d8b68c941d2e70bf86d 242 SUPERFAMILY SSF53167 2 233 4.45E-80 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CFK41_RS10715 077854439b6b9d8b68c941d2e70bf86d 242 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 1 234 42.936 T 28-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 CFK41_RS10715 077854439b6b9d8b68c941d2e70bf86d 242 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 4 233 5.6E-92 T 28-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 CFK41_RS15850 421cb6206256602b876aa4d76c997ca3 320 Pfam PF02485 Core-2/I-Branching enzyme 172 283 2.4E-6 T 28-03-2018 IPR003406 Glycosyl transferase, family 14 GO:0008375|GO:0016020 CFK41_RS14065 f02c3195ba55714e4e1fca35e97855a3 122 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 117 2.3E-4 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CFK41_RS14065 f02c3195ba55714e4e1fca35e97855a3 122 SUPERFAMILY SSF54593 4 119 4.09E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS14065 f02c3195ba55714e4e1fca35e97855a3 122 Gene3D G3DSA:3.10.180.10 8 122 1.1E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS04830 2e12b478d930873c5d16bc1ce21bcfda 210 Gene3D G3DSA:3.40.50.880 14 209 6.7E-22 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS04830 2e12b478d930873c5d16bc1ce21bcfda 210 SUPERFAMILY SSF52317 49 195 8.39E-13 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS04830 2e12b478d930873c5d16bc1ce21bcfda 210 Pfam PF03575 Peptidase family S51 51 207 6.4E-19 T 28-03-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 CFK41_RS06630 72801d88d9643322b2089a595955bf8a 252 Pfam PF03725 3' exoribonuclease family, domain 2 170 236 3.8E-11 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CFK41_RS06630 72801d88d9643322b2089a595955bf8a 252 Hamap MF_00564 Ribonuclease PH [rph]. 11 249 45.803 T 28-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 CFK41_RS06630 72801d88d9643322b2089a595955bf8a 252 SUPERFAMILY SSF55666 167 250 7.72E-23 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CFK41_RS06630 72801d88d9643322b2089a595955bf8a 252 Gene3D G3DSA:3.30.230.70 1 252 1.2E-60 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CFK41_RS06630 72801d88d9643322b2089a595955bf8a 252 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 12 248 7.8E-109 T 28-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 CFK41_RS06630 72801d88d9643322b2089a595955bf8a 252 Pfam PF01138 3' exoribonuclease family, domain 1 20 150 1.5E-24 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CFK41_RS06630 72801d88d9643322b2089a595955bf8a 252 SUPERFAMILY SSF54211 10 192 1.16E-44 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CFK41_RS06630 72801d88d9643322b2089a595955bf8a 252 ProSitePatterns PS01277 Ribonuclease PH signature. 126 139 - T 28-03-2018 IPR018336 Ribonuclease PH, conserved site CFK41_RS10445 5da65361d8bce982866961360d87416e 321 Pfam PF01263 Aldose 1-epimerase 24 316 5.9E-43 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 CFK41_RS10445 5da65361d8bce982866961360d87416e 321 SUPERFAMILY SSF74650 21 317 5.97E-57 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CFK41_RS10445 5da65361d8bce982866961360d87416e 321 Gene3D G3DSA:2.70.98.10 12 321 5.6E-67 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CFK41_RS02490 b502cdf3c9088d031ad502765610c8e7 1546 Pfam PF13439 Glycosyltransferase Family 4 1271 1354 6.2E-7 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CFK41_RS02490 b502cdf3c9088d031ad502765610c8e7 1546 Gene3D G3DSA:3.40.50.2000 1355 1518 2.8E-14 T 28-03-2018 CFK41_RS02490 b502cdf3c9088d031ad502765610c8e7 1546 Gene3D G3DSA:3.40.50.2000 870 1033 0.014 T 28-03-2018 CFK41_RS02490 b502cdf3c9088d031ad502765610c8e7 1546 SUPERFAMILY SSF53756 307 701 1.66E-49 T 28-03-2018 CFK41_RS02490 b502cdf3c9088d031ad502765610c8e7 1546 Gene3D G3DSA:1.20.1170.10 14 187 2.3E-6 T 28-03-2018 CFK41_RS02490 b502cdf3c9088d031ad502765610c8e7 1546 Pfam PF13579 Glycosyl transferase 4-like domain 320 497 9.2E-19 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CFK41_RS02490 b502cdf3c9088d031ad502765610c8e7 1546 Gene3D G3DSA:3.40.50.2000 313 513 1.6E-21 T 28-03-2018 CFK41_RS02490 b502cdf3c9088d031ad502765610c8e7 1546 Gene3D G3DSA:3.40.50.2000 1165 1354 0.0095 T 28-03-2018 CFK41_RS02490 b502cdf3c9088d031ad502765610c8e7 1546 SUPERFAMILY SSF53756 1270 1494 2.67E-23 T 28-03-2018 CFK41_RS02490 b502cdf3c9088d031ad502765610c8e7 1546 Gene3D G3DSA:3.40.50.2000 514 688 1.9E-25 T 28-03-2018 CFK41_RS02490 b502cdf3c9088d031ad502765610c8e7 1546 Pfam PF00534 Glycosyl transferases group 1 518 686 1.3E-16 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CFK41_RS17185 48293f6fed122d8fb327bb7285dd6432 335 SUPERFAMILY SSF51735 9 155 1.07E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS17185 48293f6fed122d8fb327bb7285dd6432 335 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 55 127 8.4E-17 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS17185 48293f6fed122d8fb327bb7285dd6432 335 Gene3D G3DSA:3.40.50.720 7 140 3.4E-28 T 28-03-2018 CFK41_RS17185 48293f6fed122d8fb327bb7285dd6432 335 SUPERFAMILY SSF55347 133 271 6.87E-21 T 28-03-2018 CFK41_RS17185 48293f6fed122d8fb327bb7285dd6432 335 Gene3D G3DSA:3.30.360.10 141 335 2.7E-34 T 28-03-2018 CFK41_RS04355 8ec57c6008611a72fa54c82b2a784923 364 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 114 362 1.7E-68 T 28-03-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 CFK41_RS04355 8ec57c6008611a72fa54c82b2a784923 364 Pfam PF01578 Cytochrome C assembly protein 135 359 1.6E-38 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 CFK41_RS16075 09a8b3c8465115fc4ff1cf89f23ccbc6 337 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 85 148 1.1E-13 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CFK41_RS16075 09a8b3c8465115fc4ff1cf89f23ccbc6 337 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 305 4.6E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS16075 09a8b3c8465115fc4ff1cf89f23ccbc6 337 SUPERFAMILY SSF161098 86 291 3.01E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS16075 09a8b3c8465115fc4ff1cf89f23ccbc6 337 Gene3D G3DSA:1.10.3720.10 49 310 1.2E-38 T 28-03-2018 CFK41_RS15055 297718932584a24c1ce7673a0e5922a6 101 Gene3D G3DSA:4.10.830.10 1 101 1.9E-30 T 28-03-2018 CFK41_RS15055 297718932584a24c1ce7673a0e5922a6 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 25.722 T 28-03-2018 IPR023036 Ribosomal protein S14, bacterial/plastid CFK41_RS15055 297718932584a24c1ce7673a0e5922a6 101 SUPERFAMILY SSF57716 2 101 9.98E-33 T 28-03-2018 CFK41_RS15055 297718932584a24c1ce7673a0e5922a6 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 2.5E-24 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS05610 396822258e47ccee3d3ef7058c2612e3 430 SUPERFAMILY SSF53850 53 423 6.27E-85 T 28-03-2018 CFK41_RS05610 396822258e47ccee3d3ef7058c2612e3 430 Gene3D G3DSA:3.40.190.10 52 227 4.5E-41 T 28-03-2018 CFK41_RS05610 396822258e47ccee3d3ef7058c2612e3 430 Pfam PF13416 Bacterial extracellular solute-binding protein 68 373 8.3E-48 T 28-03-2018 CFK41_RS05610 396822258e47ccee3d3ef7058c2612e3 430 Gene3D G3DSA:3.40.190.10 228 386 6.9E-16 T 28-03-2018 CFK41_RS04700 e7d211154224f57304c0ec10824efcbc 73 Pfam PF01176 Translation initiation factor 1A / IF-1 8 71 3.4E-29 T 28-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 CFK41_RS04700 e7d211154224f57304c0ec10824efcbc 73 SMART SM00316 5 73 0.002 T 28-03-2018 IPR022967 RNA-binding domain, S1 CFK41_RS04700 e7d211154224f57304c0ec10824efcbc 73 Gene3D G3DSA:2.40.50.140 1 73 6.7E-37 T 28-03-2018 CFK41_RS04700 e7d211154224f57304c0ec10824efcbc 73 SUPERFAMILY SSF50249 4 72 1.05E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS04700 e7d211154224f57304c0ec10824efcbc 73 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 2 73 26.139 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CFK41_RS04700 e7d211154224f57304c0ec10824efcbc 73 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 4 72 1.7E-36 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CFK41_RS16905 d7741339733f74ceb2173803b9e7ca24 351 Gene3D G3DSA:3.40.50.720 1 147 4.9E-35 T 28-03-2018 CFK41_RS16905 d7741339733f74ceb2173803b9e7ca24 351 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 17 133 6.3E-24 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS16905 d7741339733f74ceb2173803b9e7ca24 351 Gene3D G3DSA:3.30.360.10 148 350 2.1E-28 T 28-03-2018 CFK41_RS16905 d7741339733f74ceb2173803b9e7ca24 351 SUPERFAMILY SSF51735 12 166 5.11E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS16905 d7741339733f74ceb2173803b9e7ca24 351 SUPERFAMILY SSF55347 148 303 1.96E-13 T 28-03-2018 CFK41_RS11195 ffbad18007a1602ca29a2394be4a0e4a 209 SUPERFAMILY SSF55811 34 173 1.34E-20 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CFK41_RS11195 ffbad18007a1602ca29a2394be4a0e4a 209 Gene3D G3DSA:3.90.79.10 24 193 1.5E-20 T 28-03-2018 CFK41_RS11195 ffbad18007a1602ca29a2394be4a0e4a 209 Pfam PF00293 NUDIX domain 57 174 5.8E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CFK41_RS11195 ffbad18007a1602ca29a2394be4a0e4a 209 PRINTS PR00502 NUDIX hydrolase family signature 83 97 3.2E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CFK41_RS11195 ffbad18007a1602ca29a2394be4a0e4a 209 PRINTS PR00502 NUDIX hydrolase family signature 98 113 3.2E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CFK41_RS10605 03c92ed73aa8fae0540fba26260912e6 368 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 12 350 3.8E-71 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CFK41_RS10605 03c92ed73aa8fae0540fba26260912e6 368 SUPERFAMILY SSF51395 9 355 1.47E-114 T 28-03-2018 CFK41_RS10605 03c92ed73aa8fae0540fba26260912e6 368 Gene3D G3DSA:3.20.20.70 2 363 1.3E-122 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS04135 5b45ed5d5a2eaf8e73180232a3a4230a 153 Gene3D G3DSA:1.10.10.10 4 149 3.6E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS04135 5b45ed5d5a2eaf8e73180232a3a4230a 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 3.4E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS04135 5b45ed5d5a2eaf8e73180232a3a4230a 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 3.4E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS04135 5b45ed5d5a2eaf8e73180232a3a4230a 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 3.4E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS04135 5b45ed5d5a2eaf8e73180232a3a4230a 153 SUPERFAMILY SSF46785 13 131 1.37E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS04135 5b45ed5d5a2eaf8e73180232a3a4230a 153 Pfam PF01047 MarR family 39 98 1.5E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS04135 5b45ed5d5a2eaf8e73180232a3a4230a 153 SMART SM00347 32 134 1.4E-18 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS11760 80bcb0a8a0168cf96b1b68e29e381082 228 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 8 171 17.554 T 28-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 CFK41_RS11760 80bcb0a8a0168cf96b1b68e29e381082 228 Gene3D G3DSA:3.30.300.70 3 88 3.6E-14 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CFK41_RS11760 80bcb0a8a0168cf96b1b68e29e381082 228 Pfam PF02576 RimP N-terminal domain 16 91 9.6E-9 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CFK41_RS11760 80bcb0a8a0168cf96b1b68e29e381082 228 SUPERFAMILY SSF75420 8 91 3.66E-11 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CFK41_RS08505 6644e2dee075ee64db0276a388f09e26 247 ProDom PD037701 MEMBRANE INTEGRAL TRANSMEMBRANE RV2219/MT2276 NARROWLY PROBABLE PRECURSOR SIGNAL MLCB22.21 21 241 2.0E-44 T 28-03-2018 CFK41_RS08505 6644e2dee075ee64db0276a388f09e26 247 Pfam PF13829 Domain of unknown function (DUF4191) 20 242 4.7E-72 T 28-03-2018 IPR025445 Protein of unknown function DUF4191 CFK41_RS11310 b2a06e84038eb6cbca01251a0e7c554f 372 TIGRFAM TIGR01900 dapE-gram_pos: succinyl-diaminopimelate desuccinylase 16 368 3.7E-145 T 28-03-2018 IPR010174 Succinyl-diaminopimelate desuccinylase, DapE GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 CFK41_RS11310 b2a06e84038eb6cbca01251a0e7c554f 372 Gene3D G3DSA:3.40.630.10 1 369 6.2E-48 T 28-03-2018 CFK41_RS11310 b2a06e84038eb6cbca01251a0e7c554f 372 SUPERFAMILY SSF53187 16 188 5.71E-37 T 28-03-2018 CFK41_RS11310 b2a06e84038eb6cbca01251a0e7c554f 372 SUPERFAMILY SSF53187 296 367 5.71E-37 T 28-03-2018 CFK41_RS11310 b2a06e84038eb6cbca01251a0e7c554f 372 SUPERFAMILY SSF55031 180 283 7.18E-19 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CFK41_RS11310 b2a06e84038eb6cbca01251a0e7c554f 372 Pfam PF01546 Peptidase family M20/M25/M40 75 368 3.9E-21 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CFK41_RS11310 b2a06e84038eb6cbca01251a0e7c554f 372 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 74 83 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CFK41_RS11310 b2a06e84038eb6cbca01251a0e7c554f 372 Pfam PF07687 Peptidase dimerisation domain 179 279 2.2E-16 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CFK41_RS04920 d38b3e4469996241d1842174c872ba97 509 Gene3D G3DSA:3.40.50.10260 2 219 1.2E-46 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CFK41_RS04920 d38b3e4469996241d1842174c872ba97 509 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 441 451 - T 28-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site CFK41_RS04920 d38b3e4469996241d1842174c872ba97 509 Pfam PF01256 Carbohydrate kinase 250 482 1.1E-39 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CFK41_RS04920 d38b3e4469996241d1842174c872ba97 509 SUPERFAMILY SSF64153 5 247 4.45E-42 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CFK41_RS04920 d38b3e4469996241d1842174c872ba97 509 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 226 505 19.275 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CFK41_RS04920 d38b3e4469996241d1842174c872ba97 509 Gene3D G3DSA:3.40.1190.20 223 508 1.0E-39 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS04920 d38b3e4469996241d1842174c872ba97 509 PIRSF PIRSF017184 5 507 1.9E-87 T 28-03-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 CFK41_RS04920 d38b3e4469996241d1842174c872ba97 509 SUPERFAMILY SSF53613 226 501 3.47E-48 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS04920 d38b3e4469996241d1842174c872ba97 509 Pfam PF03853 YjeF-related protein N-terminus 22 192 5.3E-31 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CFK41_RS04920 d38b3e4469996241d1842174c872ba97 509 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 228 500 8.9E-45 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CFK41_RS04920 d38b3e4469996241d1842174c872ba97 509 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 2 213 19.946 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CFK41_RS07730 44d5986bf1f60812c86491d958cd249a 339 Gene3D G3DSA:1.10.260.40 3 59 2.3E-16 T 28-03-2018 CFK41_RS07730 44d5986bf1f60812c86491d958cd249a 339 Pfam PF13377 Periplasmic binding protein-like domain 175 333 3.2E-33 T 28-03-2018 CFK41_RS07730 44d5986bf1f60812c86491d958cd249a 339 SUPERFAMILY SSF53822 66 337 1.34E-59 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS07730 44d5986bf1f60812c86491d958cd249a 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 53 1.2E-11 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS07730 44d5986bf1f60812c86491d958cd249a 339 SMART SM00354 4 76 2.8E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS07730 44d5986bf1f60812c86491d958cd249a 339 SUPERFAMILY SSF47413 3 63 1.35E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS07730 44d5986bf1f60812c86491d958cd249a 339 Gene3D G3DSA:3.40.50.2300 60 179 2.7E-24 T 28-03-2018 CFK41_RS07730 44d5986bf1f60812c86491d958cd249a 339 Gene3D G3DSA:3.40.50.2300 180 313 1.2E-39 T 28-03-2018 CFK41_RS09445 67574966b8aabbae56f3c313d7819354 310 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 9 256 3.6E-64 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CFK41_RS09445 67574966b8aabbae56f3c313d7819354 310 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 8 260 9.3E-49 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CFK41_RS09445 67574966b8aabbae56f3c313d7819354 310 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 136 148 - T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CFK41_RS09445 67574966b8aabbae56f3c313d7819354 310 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 4 262 15.927 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CFK41_RS00305 5c44274d8cb90e78ddc460190347e028 239 SMART SM00422 6 75 2.8E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS00305 5c44274d8cb90e78ddc460190347e028 239 Gene3D G3DSA:1.10.1660.10 3 60 8.0E-16 T 28-03-2018 CFK41_RS00305 5c44274d8cb90e78ddc460190347e028 239 SUPERFAMILY SSF46955 6 108 6.23E-21 T 28-03-2018 IPR009061 Putative DNA-binding domain CFK41_RS00305 5c44274d8cb90e78ddc460190347e028 239 Pfam PF13411 MerR HTH family regulatory protein 7 72 2.6E-12 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS00305 5c44274d8cb90e78ddc460190347e028 239 Gene3D G3DSA:1.10.1660.10 61 126 1.5E-6 T 28-03-2018 CFK41_RS03600 e309303be3d05cd5fa328919a5a28324 320 Gene3D G3DSA:1.10.3720.10 28 320 5.2E-35 T 28-03-2018 CFK41_RS03600 e309303be3d05cd5fa328919a5a28324 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 315 8.3E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS03600 e309303be3d05cd5fa328919a5a28324 320 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 29 315 1.9E-77 T 28-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 CFK41_RS03600 e309303be3d05cd5fa328919a5a28324 320 SUPERFAMILY SSF161098 71 309 4.06E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS17010 9053d4c9d4d7d468af366b3f4f6a8d73 464 SMART SM00922 197 293 3.0E-21 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CFK41_RS17010 9053d4c9d4d7d468af366b3f4f6a8d73 464 SUPERFAMILY SSF54826 5 135 8.25E-34 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS17010 9053d4c9d4d7d468af366b3f4f6a8d73 464 Gene3D G3DSA:3.20.20.120 178 438 1.6E-57 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS17010 9053d4c9d4d7d468af366b3f4f6a8d73 464 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 28 131 6.4E-8 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CFK41_RS17010 9053d4c9d4d7d468af366b3f4f6a8d73 464 Gene3D G3DSA:3.30.390.10 1 177 2.7E-37 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS17010 9053d4c9d4d7d468af366b3f4f6a8d73 464 Pfam PF13378 Enolase C-terminal domain-like 206 413 8.4E-54 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS17010 9053d4c9d4d7d468af366b3f4f6a8d73 464 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 243 274 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CFK41_RS17010 9053d4c9d4d7d468af366b3f4f6a8d73 464 SUPERFAMILY SSF51604 182 428 1.7E-61 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS13955 61f71957649f99eb9e55ec77c130bc5f 500 SUPERFAMILY SSF53850 113 485 5.61E-55 T 28-03-2018 CFK41_RS13955 61f71957649f99eb9e55ec77c130bc5f 500 Pfam PF13416 Bacterial extracellular solute-binding protein 120 412 6.7E-29 T 28-03-2018 CFK41_RS13955 61f71957649f99eb9e55ec77c130bc5f 500 Gene3D G3DSA:3.40.190.10 96 227 2.2E-16 T 28-03-2018 CFK41_RS13955 61f71957649f99eb9e55ec77c130bc5f 500 Gene3D G3DSA:3.40.190.10 228 493 4.5E-31 T 28-03-2018 CFK41_RS13660 444804f01c6fbc794bfb43a5b2c0abfb 289 Gene3D G3DSA:3.40.250.10 5 164 9.1E-26 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS13660 444804f01c6fbc794bfb43a5b2c0abfb 289 SUPERFAMILY SSF52821 171 287 3.14E-32 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS13660 444804f01c6fbc794bfb43a5b2c0abfb 289 ProSitePatterns PS00380 Rhodanese signature 1. 53 64 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CFK41_RS13660 444804f01c6fbc794bfb43a5b2c0abfb 289 Gene3D G3DSA:3.40.250.10 165 289 4.1E-26 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS13660 444804f01c6fbc794bfb43a5b2c0abfb 289 SMART SM00450 162 281 1.8E-17 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS13660 444804f01c6fbc794bfb43a5b2c0abfb 289 SMART SM00450 18 145 2.5E-13 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS13660 444804f01c6fbc794bfb43a5b2c0abfb 289 SUPERFAMILY SSF52821 10 159 3.4E-33 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS13660 444804f01c6fbc794bfb43a5b2c0abfb 289 Pfam PF00581 Rhodanese-like domain 31 140 7.7E-15 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS13660 444804f01c6fbc794bfb43a5b2c0abfb 289 Pfam PF00581 Rhodanese-like domain 174 277 3.7E-13 T 28-03-2018 IPR001763 Rhodanese-like domain CFK41_RS14140 8598c4e152ece7e26fff3a412d998692 216 SUPERFAMILY SSF54593 7 126 8.07E-9 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS14140 8598c4e152ece7e26fff3a412d998692 216 Gene3D G3DSA:3.10.180.10 3 216 1.9E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS14140 8598c4e152ece7e26fff3a412d998692 216 Pfam PF13468 Glyoxalase-like domain 7 181 9.8E-38 T 28-03-2018 IPR025870 Glyoxalase-like domain CFK41_RS02200 5d0456e14df24bb52d1fa90695594269 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 283 2.3E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS02200 5d0456e14df24bb52d1fa90695594269 287 Gene3D G3DSA:1.20.58.370 1 40 7.2E-4 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CFK41_RS02200 5d0456e14df24bb52d1fa90695594269 287 Gene3D G3DSA:1.10.3720.10 57 283 1.7E-46 T 28-03-2018 CFK41_RS02200 5d0456e14df24bb52d1fa90695594269 287 SUPERFAMILY SSF161098 50 272 3.27E-55 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS04585 8c303f1db6e87648ad61a2e95fe4e9e9 100 SUPERFAMILY SSF54189 7 91 1.12E-30 T 28-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS04585 8c303f1db6e87648ad61a2e95fe4e9e9 100 Gene3D G3DSA:3.30.70.330 6 99 3.6E-30 T 28-03-2018 CFK41_RS04585 8c303f1db6e87648ad61a2e95fe4e9e9 100 Pfam PF00276 Ribosomal protein L23 10 90 5.5E-31 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CFK41_RS04585 8c303f1db6e87648ad61a2e95fe4e9e9 100 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 9 97 21.38 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CFK41_RS14105 992ba11652db7d98ef184aacee6d0c47 362 Gene3D G3DSA:3.20.20.70 13 362 1.2E-115 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS14105 992ba11652db7d98ef184aacee6d0c47 362 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 13 357 1.1E-136 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CFK41_RS14105 992ba11652db7d98ef184aacee6d0c47 362 PIRSF PIRSF001361 3 361 3.5E-145 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CFK41_RS14105 992ba11652db7d98ef184aacee6d0c47 362 SUPERFAMILY SSF51569 13 356 1.57E-120 T 28-03-2018 CFK41_RS14105 992ba11652db7d98ef184aacee6d0c47 362 Pfam PF00793 DAHP synthetase I family 49 346 3.2E-87 T 28-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CFK41_RS00445 70ef26b89ebbbe75d03a0d8bc3cc2c55 221 Pfam PF00072 Response regulator receiver domain 4 115 1.1E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS00445 70ef26b89ebbbe75d03a0d8bc3cc2c55 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 2.6E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS00445 70ef26b89ebbbe75d03a0d8bc3cc2c55 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 2.6E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS00445 70ef26b89ebbbe75d03a0d8bc3cc2c55 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 2.6E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS00445 70ef26b89ebbbe75d03a0d8bc3cc2c55 221 SMART SM00421 152 209 2.3E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS00445 70ef26b89ebbbe75d03a0d8bc3cc2c55 221 Gene3D G3DSA:3.40.50.2300 1 126 1.6E-35 T 28-03-2018 CFK41_RS00445 70ef26b89ebbbe75d03a0d8bc3cc2c55 221 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS00445 70ef26b89ebbbe75d03a0d8bc3cc2c55 221 Gene3D G3DSA:1.10.10.10 127 219 2.1E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS00445 70ef26b89ebbbe75d03a0d8bc3cc2c55 221 SUPERFAMILY SSF46894 136 215 4.76E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CFK41_RS00445 70ef26b89ebbbe75d03a0d8bc3cc2c55 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 209 2.6E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS00445 70ef26b89ebbbe75d03a0d8bc3cc2c55 221 SUPERFAMILY SSF52172 1 132 1.38E-33 T 28-03-2018 IPR011006 CheY-like superfamily CFK41_RS00445 70ef26b89ebbbe75d03a0d8bc3cc2c55 221 SMART SM00448 2 115 2.6E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS00675 8d028abdb5823480d3d31d3cc1992a47 560 Pfam PF17392 Urocanase C-terminal domain 352 546 1.2E-90 T 28-03-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CFK41_RS00675 8d028abdb5823480d3d31d3cc1992a47 560 Pfam PF01175 Urocanase Rossmann-like domain 139 349 2.3E-81 T 28-03-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CFK41_RS00675 8d028abdb5823480d3d31d3cc1992a47 560 Hamap MF_00577 Urocanate hydratase [hutU]. 4 556 48.951 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CFK41_RS00675 8d028abdb5823480d3d31d3cc1992a47 560 ProSitePatterns PS01233 Urocanase signature. 442 457 - T 28-03-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CFK41_RS00675 8d028abdb5823480d3d31d3cc1992a47 560 PIRSF PIRSF001423 2 560 1.2E-272 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CFK41_RS00675 8d028abdb5823480d3d31d3cc1992a47 560 Pfam PF17391 Urocanase N-terminal domain 9 135 1.5E-59 T 28-03-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CFK41_RS00675 8d028abdb5823480d3d31d3cc1992a47 560 Gene3D G3DSA:3.40.1770.10 193 555 4.4E-152 T 28-03-2018 CFK41_RS00675 8d028abdb5823480d3d31d3cc1992a47 560 Gene3D G3DSA:3.40.1770.10 7 150 6.6E-24 T 28-03-2018 CFK41_RS00675 8d028abdb5823480d3d31d3cc1992a47 560 SUPERFAMILY SSF111326 6 555 3.53E-243 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CFK41_RS00675 8d028abdb5823480d3d31d3cc1992a47 560 TIGRFAM TIGR01228 hutU: urocanate hydratase 8 554 2.5E-268 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CFK41_RS08835 ddced8bc89013198c5b66d54f0573fe6 269 Gene3D G3DSA:3.40.1280.10 104 267 5.9E-47 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CFK41_RS08835 ddced8bc89013198c5b66d54f0573fe6 269 SUPERFAMILY SSF55315 3 105 4.94E-13 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CFK41_RS08835 ddced8bc89013198c5b66d54f0573fe6 269 Gene3D G3DSA:3.30.1330.30 3 103 1.2E-21 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CFK41_RS08835 ddced8bc89013198c5b66d54f0573fe6 269 Pfam PF00588 SpoU rRNA Methylase family 119 261 1.6E-30 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CFK41_RS08835 ddced8bc89013198c5b66d54f0573fe6 269 SUPERFAMILY SSF75217 96 265 7.19E-37 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CFK41_RS02710 5e25a4762e7aa3fd62d30413cdb6b4bb 918 SUPERFAMILY SSF54001 422 576 6.59E-29 T 28-03-2018 CFK41_RS02710 5e25a4762e7aa3fd62d30413cdb6b4bb 918 Pfam PF01841 Transglutaminase-like superfamily 451 566 2.3E-24 T 28-03-2018 IPR002931 Transglutaminase-like CFK41_RS02710 5e25a4762e7aa3fd62d30413cdb6b4bb 918 SMART SM00460 498 568 2.7E-15 T 28-03-2018 IPR002931 Transglutaminase-like CFK41_RS02710 5e25a4762e7aa3fd62d30413cdb6b4bb 918 Gene3D G3DSA:3.90.260.10 449 594 2.1E-18 T 28-03-2018 IPR002931 Transglutaminase-like CFK41_RS03275 60454ba42a4eb4e9fa4c77f686bbae31 325 Pfam PF01032 FecCD transport family 7 317 1.9E-69 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CFK41_RS03275 60454ba42a4eb4e9fa4c77f686bbae31 325 Gene3D G3DSA:1.10.3470.10 1 324 5.2E-52 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CFK41_RS03275 60454ba42a4eb4e9fa4c77f686bbae31 325 SUPERFAMILY SSF81345 6 317 4.97E-59 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CFK41_RS12445 f04670c0c5d0deea9290fcdfa805cb26 265 Pfam PF03932 CutC family 4 234 7.2E-40 T 28-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 CFK41_RS12445 f04670c0c5d0deea9290fcdfa805cb26 265 SUPERFAMILY SSF110395 5 258 3.66E-37 T 28-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 CFK41_RS12445 f04670c0c5d0deea9290fcdfa805cb26 265 Gene3D G3DSA:3.20.20.380 2 260 2.5E-56 T 28-03-2018 CFK41_RS12950 9b588b316317d7311996cfffaec83e4a 389 Pfam PF04235 Protein of unknown function (DUF418) 216 379 5.6E-27 T 28-03-2018 IPR007349 Domain of unknown function DUF418 CFK41_RS12740 ee59b90f99a932a1c8d4b6c54e43c18d 165 SUPERFAMILY SSF49299 49 95 4.19E-6 T 28-03-2018 IPR000601 PKD domain CFK41_RS12740 ee59b90f99a932a1c8d4b6c54e43c18d 165 Gene3D G3DSA:2.60.40.10 17 120 4.5E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS03155 7f8c33f82b45e8b05ed6de49e3ec86ed 414 Pfam PF00762 Ferrochelatase 36 357 5.5E-92 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CFK41_RS03155 7f8c33f82b45e8b05ed6de49e3ec86ed 414 Gene3D G3DSA:3.40.50.1400 31 188 2.5E-23 T 28-03-2018 CFK41_RS03155 7f8c33f82b45e8b05ed6de49e3ec86ed 414 SUPERFAMILY SSF53800 33 386 1.39E-78 T 28-03-2018 CFK41_RS03155 7f8c33f82b45e8b05ed6de49e3ec86ed 414 TIGRFAM TIGR00109 hemH: ferrochelatase 37 358 3.3E-44 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CFK41_RS03155 7f8c33f82b45e8b05ed6de49e3ec86ed 414 ProSitePatterns PS00534 Ferrochelatase signature. 211 233 - T 28-03-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CFK41_RS03155 7f8c33f82b45e8b05ed6de49e3ec86ed 414 Hamap MF_00323 Ferrochelatase [hemH]. 34 358 30.89 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CFK41_RS03155 7f8c33f82b45e8b05ed6de49e3ec86ed 414 Gene3D G3DSA:3.40.50.1400 189 339 2.2E-47 T 28-03-2018 CFK41_RS01650 dbd1fa1534eed61d31c95c16db629762 494 Gene3D G3DSA:2.115.10.20 39 398 4.4E-55 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CFK41_RS01650 dbd1fa1534eed61d31c95c16db629762 494 Pfam PF04616 Glycosyl hydrolases family 43 48 291 6.6E-20 T 28-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 CFK41_RS01650 dbd1fa1534eed61d31c95c16db629762 494 Pfam PF16369 C-terminal of Glycosyl hydrolases family 43 382 490 1.0E-24 T 28-03-2018 IPR032291 Extracellular endo-alpha-(1->5)-L-arabinanase, C-terminal CFK41_RS01650 dbd1fa1534eed61d31c95c16db629762 494 SUPERFAMILY SSF75005 40 295 2.0E-48 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CFK41_RS01650 dbd1fa1534eed61d31c95c16db629762 494 SUPERFAMILY SSF75005 323 380 2.0E-48 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CFK41_RS01650 dbd1fa1534eed61d31c95c16db629762 494 Gene3D G3DSA:2.40.128.10 400 492 7.4E-24 T 28-03-2018 CFK41_RS12330 4177048c9b92c8b5a8cc00a1b846ef8d 874 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 535 709 1.3E-20 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CFK41_RS12330 4177048c9b92c8b5a8cc00a1b846ef8d 874 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 535 709 4.6E-25 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CFK41_RS05625 f284ad636c27a8a656ada2e64db964e8 519 Pfam PF11329 Protein of unknown function (DUF3131) 57 203 1.0E-6 T 28-03-2018 IPR021478 Protein of unknown function DUF3131 CFK41_RS05625 f284ad636c27a8a656ada2e64db964e8 519 Pfam PF10091 Putative glucoamylase 310 487 3.1E-12 T 28-03-2018 IPR019282 Domain of unknown function DUF2329 CFK41_RS02435 517855c6d2f1f938ac1b31757c74f241 390 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 23 372 7.5E-113 T 28-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 CFK41_RS02435 517855c6d2f1f938ac1b31757c74f241 390 Gene3D G3DSA:3.40.50.2000 1 211 4.7E-67 T 28-03-2018 CFK41_RS02435 517855c6d2f1f938ac1b31757c74f241 390 SUPERFAMILY SSF53756 1 376 2.76E-121 T 28-03-2018 CFK41_RS02435 517855c6d2f1f938ac1b31757c74f241 390 Gene3D G3DSA:3.40.50.2000 212 352 6.1E-39 T 28-03-2018 CFK41_RS02435 517855c6d2f1f938ac1b31757c74f241 390 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 3 374 5.3E-136 T 28-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 CFK41_RS12680 7ddd8398e50fbac55c61224d983a715c 699 ProSitePatterns PS00211 ABC transporters family signature. 506 520 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS12680 7ddd8398e50fbac55c61224d983a715c 699 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 583 677 5.8E-19 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CFK41_RS12680 7ddd8398e50fbac55c61224d983a715c 699 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 320 3.4E-24 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CFK41_RS12680 7ddd8398e50fbac55c61224d983a715c 699 SMART SM00382 34 233 2.0E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS12680 7ddd8398e50fbac55c61224d983a715c 699 SMART SM00382 392 583 8.9E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS12680 7ddd8398e50fbac55c61224d983a715c 699 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 585 647 1.3E-15 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CFK41_RS12680 7ddd8398e50fbac55c61224d983a715c 699 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 300 7.5E-19 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CFK41_RS12680 7ddd8398e50fbac55c61224d983a715c 699 Gene3D G3DSA:3.40.50.300 2 335 1.8E-72 T 28-03-2018 CFK41_RS12680 7ddd8398e50fbac55c61224d983a715c 699 Gene3D G3DSA:3.40.50.300 352 692 5.2E-74 T 28-03-2018 CFK41_RS12680 7ddd8398e50fbac55c61224d983a715c 699 SUPERFAMILY SSF52540 5 254 3.24E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS12680 7ddd8398e50fbac55c61224d983a715c 699 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS12680 7ddd8398e50fbac55c61224d983a715c 699 SUPERFAMILY SSF52540 372 605 3.24E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS12680 7ddd8398e50fbac55c61224d983a715c 699 Pfam PF00005 ABC transporter 26 183 6.1E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS12680 7ddd8398e50fbac55c61224d983a715c 699 Pfam PF00005 ABC transporter 384 533 2.7E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS11005 66589c6b0f460fbe10f6d8bed2e4d781 343 Pfam PF01494 FAD binding domain 254 284 1.7E-6 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CFK41_RS11005 66589c6b0f460fbe10f6d8bed2e4d781 343 Gene3D G3DSA:3.50.50.60 1 340 7.3E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS11005 66589c6b0f460fbe10f6d8bed2e4d781 343 Pfam PF13450 NAD(P)-binding Rossmann-like domain 9 36 1.5E-5 T 28-03-2018 CFK41_RS11005 66589c6b0f460fbe10f6d8bed2e4d781 343 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 267 283 1.9E-13 T 28-03-2018 CFK41_RS11005 66589c6b0f460fbe10f6d8bed2e4d781 343 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 252 267 1.9E-13 T 28-03-2018 CFK41_RS11005 66589c6b0f460fbe10f6d8bed2e4d781 343 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 1.9E-13 T 28-03-2018 CFK41_RS11005 66589c6b0f460fbe10f6d8bed2e4d781 343 SUPERFAMILY SSF51905 239 325 1.13E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS11005 66589c6b0f460fbe10f6d8bed2e4d781 343 SUPERFAMILY SSF51905 9 150 1.13E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS05595 47d27208ad42076a87eaec3260306d39 284 Pfam PF02535 ZIP Zinc transporter 98 271 4.1E-22 T 28-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 CFK41_RS05595 47d27208ad42076a87eaec3260306d39 284 Hamap MF_00548 Zinc transporter ZupT [zupT]. 1 277 30.726 T 28-03-2018 IPR023498 Zinc transporter ZupT CFK41_RS07605 bad3e64fc26634e32f7b608282bc86b4 336 SUPERFAMILY SSF50331 235 332 3.29E-8 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CFK41_RS07605 bad3e64fc26634e32f7b608282bc86b4 336 SMART SM00382 22 207 5.2E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS07605 bad3e64fc26634e32f7b608282bc86b4 336 Gene3D G3DSA:2.40.50.100 281 336 0.13 T 28-03-2018 CFK41_RS07605 bad3e64fc26634e32f7b608282bc86b4 336 Pfam PF00005 ABC transporter 16 159 1.4E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS07605 bad3e64fc26634e32f7b608282bc86b4 336 SUPERFAMILY SSF52540 15 232 1.39E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS07605 bad3e64fc26634e32f7b608282bc86b4 336 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS07605 bad3e64fc26634e32f7b608282bc86b4 336 Gene3D G3DSA:3.40.50.300 15 238 3.0E-65 T 28-03-2018 CFK41_RS07235 f857c551bcd3bf417ec6d2143dc44009 585 SUPERFAMILY SSF52518 3 185 1.59E-60 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CFK41_RS07235 f857c551bcd3bf417ec6d2143dc44009 585 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 432 451 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CFK41_RS07235 f857c551bcd3bf417ec6d2143dc44009 585 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 395 549 2.5E-49 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CFK41_RS07235 f857c551bcd3bf417ec6d2143dc44009 585 SUPERFAMILY SSF52467 189 362 1.62E-54 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CFK41_RS07235 f857c551bcd3bf417ec6d2143dc44009 585 Gene3D G3DSA:3.40.50.970 356 562 7.1E-46 T 28-03-2018 CFK41_RS07235 f857c551bcd3bf417ec6d2143dc44009 585 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 6 571 6.2E-220 T 28-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CFK41_RS07235 f857c551bcd3bf417ec6d2143dc44009 585 Gene3D G3DSA:3.40.50.970 1 182 3.6E-59 T 28-03-2018 CFK41_RS07235 f857c551bcd3bf417ec6d2143dc44009 585 SUPERFAMILY SSF52518 375 570 2.86E-63 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CFK41_RS07235 f857c551bcd3bf417ec6d2143dc44009 585 Gene3D G3DSA:3.40.50.1220 192 355 1.9E-51 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CFK41_RS07235 f857c551bcd3bf417ec6d2143dc44009 585 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 6 172 5.5E-55 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CFK41_RS07235 f857c551bcd3bf417ec6d2143dc44009 585 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 196 331 5.0E-42 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CFK41_RS01290 7c7b5551b7aaf2b103766b0766308f11 434 Gene3D G3DSA:3.40.190.10 35 206 1.5E-26 T 28-03-2018 CFK41_RS01290 7c7b5551b7aaf2b103766b0766308f11 434 Pfam PF01547 Bacterial extracellular solute-binding protein 52 341 2.0E-25 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CFK41_RS01290 7c7b5551b7aaf2b103766b0766308f11 434 Gene3D G3DSA:3.40.190.10 211 377 3.5E-7 T 28-03-2018 CFK41_RS01290 7c7b5551b7aaf2b103766b0766308f11 434 SUPERFAMILY SSF53850 21 433 1.19E-51 T 28-03-2018 CFK41_RS03350 a93d0d2ffb243f76dcd91775b2c97759 654 TIGRFAM TIGR04225 CshA_fibril_rpt: CshA-type fibril repeat 519 589 9.3E-18 T 28-03-2018 IPR026395 CshA-type fibril repeat CFK41_RS03350 a93d0d2ffb243f76dcd91775b2c97759 654 Gene3D G3DSA:2.60.500.10 377 481 1.3E-4 T 28-03-2018 CFK41_RS03350 a93d0d2ffb243f76dcd91775b2c97759 654 Gene3D G3DSA:2.60.500.10 482 597 1.8E-12 T 28-03-2018 CFK41_RS07020 01ee333af5df705029f2be3697dbf1f1 340 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 206 1.1E-51 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 CFK41_RS07020 01ee333af5df705029f2be3697dbf1f1 340 Gene3D G3DSA:3.90.870.10 1 212 5.7E-62 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CFK41_RS07020 01ee333af5df705029f2be3697dbf1f1 340 SUPERFAMILY SSF55821 12 210 7.63E-52 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CFK41_RS07020 01ee333af5df705029f2be3697dbf1f1 340 Pfam PF01300 Telomere recombination 22 196 1.4E-40 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 CFK41_RS15470 2da4b47f4f7600dc502b95321bb83df6 273 SUPERFAMILY SSF56655 3 250 6.15E-51 T 28-03-2018 CFK41_RS15470 2da4b47f4f7600dc502b95321bb83df6 273 Gene3D G3DSA:3.30.540.10 1 149 9.5E-38 T 28-03-2018 CFK41_RS15470 2da4b47f4f7600dc502b95321bb83df6 273 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 9.2E-23 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CFK41_RS15470 2da4b47f4f7600dc502b95321bb83df6 273 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 9.2E-23 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CFK41_RS15470 2da4b47f4f7600dc502b95321bb83df6 273 PRINTS PR00377 Inositol monophosphatase superfamily signature 184 205 9.2E-23 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CFK41_RS15470 2da4b47f4f7600dc502b95321bb83df6 273 PRINTS PR00377 Inositol monophosphatase superfamily signature 215 239 9.2E-23 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CFK41_RS15470 2da4b47f4f7600dc502b95321bb83df6 273 PRINTS PR00377 Inositol monophosphatase superfamily signature 82 98 9.2E-23 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CFK41_RS15470 2da4b47f4f7600dc502b95321bb83df6 273 Pfam PF00459 Inositol monophosphatase family 3 241 2.3E-39 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CFK41_RS15470 2da4b47f4f7600dc502b95321bb83df6 273 Gene3D G3DSA:3.40.190.80 150 263 7.3E-10 T 28-03-2018 CFK41_RS05090 f3ff60b911795ba2fe8f3c7115e61484 164 SUPERFAMILY SSF81301 13 109 8.17E-7 T 28-03-2018 CFK41_RS17480 0271252a0c575ec6d197480ca90f881e 45 ProSitePatterns PS00784 Ribosomal protein L34 signature. 3 22 - T 28-03-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS17480 0271252a0c575ec6d197480ca90f881e 45 Pfam PF00468 Ribosomal protein L34 3 45 6.8E-22 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS17480 0271252a0c575ec6d197480ca90f881e 45 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 3 43 5.0E-12 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS17480 0271252a0c575ec6d197480ca90f881e 45 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 3 45 1.2E-21 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS17480 0271252a0c575ec6d197480ca90f881e 45 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 2 45 16.08 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS09885 85d2a83bf3c9ea42c3fe86b4dbb67c35 119 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 101 118 - T 28-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 CFK41_RS09885 85d2a83bf3c9ea42c3fe86b4dbb67c35 119 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 15 119 2.8E-35 T 28-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 CFK41_RS09885 85d2a83bf3c9ea42c3fe86b4dbb67c35 119 SUPERFAMILY SSF89360 15 108 8.04E-28 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CFK41_RS09885 85d2a83bf3c9ea42c3fe86b4dbb67c35 119 Gene3D G3DSA:2.60.300.12 15 119 1.1E-32 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CFK41_RS09885 85d2a83bf3c9ea42c3fe86b4dbb67c35 119 Pfam PF01521 Iron-sulphur cluster biosynthesis 15 116 6.2E-19 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CFK41_RS07970 f60249e22002d97b8f827b4bec93a45d 454 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 215 229 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CFK41_RS07970 f60249e22002d97b8f827b4bec93a45d 454 Gene3D G3DSA:3.40.640.10 19 307 3.8E-47 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS07970 f60249e22002d97b8f827b4bec93a45d 454 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 23 440 8.9E-111 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CFK41_RS07970 f60249e22002d97b8f827b4bec93a45d 454 Gene3D G3DSA:3.90.1150.10 309 452 5.9E-43 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS07970 f60249e22002d97b8f827b4bec93a45d 454 SUPERFAMILY SSF53383 277 441 1.93E-98 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS07970 f60249e22002d97b8f827b4bec93a45d 454 SUPERFAMILY SSF53383 42 242 1.93E-98 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS07970 f60249e22002d97b8f827b4bec93a45d 454 PIRSF PIRSF001434 8 444 3.5E-113 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CFK41_RS05400 9695c7bf17f027a300add35da9629b78 198 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 54 190 1.9E-18 T 28-03-2018 IPR009936 Protein of unknown function DUF1468 CFK41_RS13915 58fdaa7b7d63c8695cdebd40be248a5c 567 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 4 567 4.1E-257 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CFK41_RS13915 58fdaa7b7d63c8695cdebd40be248a5c 567 ProSitePatterns PS00145 Urease active site. 320 336 - T 28-03-2018 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CFK41_RS13915 58fdaa7b7d63c8695cdebd40be248a5c 567 SUPERFAMILY SSF51556 481 567 4.08E-168 T 28-03-2018 IPR032466 Metal-dependent hydrolase CFK41_RS13915 58fdaa7b7d63c8695cdebd40be248a5c 567 SUPERFAMILY SSF51556 132 434 4.08E-168 T 28-03-2018 IPR032466 Metal-dependent hydrolase CFK41_RS13915 58fdaa7b7d63c8695cdebd40be248a5c 567 Gene3D G3DSA:3.20.20.140 424 553 1.9E-40 T 28-03-2018 CFK41_RS13915 58fdaa7b7d63c8695cdebd40be248a5c 567 Gene3D G3DSA:3.20.20.140 146 423 3.2E-140 T 28-03-2018 CFK41_RS13915 58fdaa7b7d63c8695cdebd40be248a5c 567 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 298 315 6.6E-32 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CFK41_RS13915 58fdaa7b7d63c8695cdebd40be248a5c 567 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 403 418 6.6E-32 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CFK41_RS13915 58fdaa7b7d63c8695cdebd40be248a5c 567 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 429 442 6.6E-32 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CFK41_RS13915 58fdaa7b7d63c8695cdebd40be248a5c 567 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 337 353 6.6E-32 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CFK41_RS13915 58fdaa7b7d63c8695cdebd40be248a5c 567 Pfam PF01979 Amidohydrolase family 128 455 5.6E-57 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CFK41_RS13915 58fdaa7b7d63c8695cdebd40be248a5c 567 Pfam PF00449 Urease alpha-subunit, N-terminal domain 3 122 2.4E-51 T 28-03-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CFK41_RS13915 58fdaa7b7d63c8695cdebd40be248a5c 567 Gene3D G3DSA:2.30.40.10 66 145 2.5E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS13915 58fdaa7b7d63c8695cdebd40be248a5c 567 ProSitePatterns PS01120 Urease nickel ligands signature. 130 143 - T 28-03-2018 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CFK41_RS13915 58fdaa7b7d63c8695cdebd40be248a5c 567 SUPERFAMILY SSF51338 1 179 7.66E-64 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS13915 58fdaa7b7d63c8695cdebd40be248a5c 567 Hamap MF_01953 Urease subunit alpha [ureC]. 2 567 52.688 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CFK41_RS05360 208b3eec04594c4d4b5745032f0a85dd 493 SUPERFAMILY SSF53720 6 482 7.07E-159 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CFK41_RS05360 208b3eec04594c4d4b5745032f0a85dd 493 Pfam PF00171 Aldehyde dehydrogenase family 14 478 7.0E-161 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CFK41_RS05360 208b3eec04594c4d4b5745032f0a85dd 493 Gene3D G3DSA:3.40.309.10 270 464 2.4E-66 T 28-03-2018 CFK41_RS05360 208b3eec04594c4d4b5745032f0a85dd 493 Gene3D G3DSA:3.40.605.10 2 269 8.0E-95 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CFK41_RS05360 208b3eec04594c4d4b5745032f0a85dd 493 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 251 258 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CFK41_RS14805 3ac5c5a04bf0893bb388bb85e578ca80 428 Pfam PF01120 Alpha-L-fucosidase 6 350 1.2E-79 T 28-03-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS14805 3ac5c5a04bf0893bb388bb85e578ca80 428 Gene3D G3DSA:3.20.20.80 4 361 1.2E-86 T 28-03-2018 CFK41_RS14805 3ac5c5a04bf0893bb388bb85e578ca80 428 PRINTS PR00741 Glycosyl hydrolase family 29 signature 115 131 3.7E-13 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS14805 3ac5c5a04bf0893bb388bb85e578ca80 428 PRINTS PR00741 Glycosyl hydrolase family 29 signature 305 326 3.7E-13 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS14805 3ac5c5a04bf0893bb388bb85e578ca80 428 PRINTS PR00741 Glycosyl hydrolase family 29 signature 208 224 3.7E-13 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS14805 3ac5c5a04bf0893bb388bb85e578ca80 428 SUPERFAMILY SSF51445 5 349 3.16E-88 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS14805 3ac5c5a04bf0893bb388bb85e578ca80 428 SMART SM00812 2 396 4.7E-99 T 28-03-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS14805 3ac5c5a04bf0893bb388bb85e578ca80 428 PIRSF PIRSF001092 3 397 2.8E-88 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS00580 cf74690672f9dae0a0354da13489e550 464 Gene3D G3DSA:3.40.190.10 274 407 1.1E-7 T 28-03-2018 CFK41_RS00580 cf74690672f9dae0a0354da13489e550 464 SUPERFAMILY SSF53850 64 443 7.06E-55 T 28-03-2018 CFK41_RS00580 cf74690672f9dae0a0354da13489e550 464 Gene3D G3DSA:3.40.190.10 55 234 5.1E-27 T 28-03-2018 CFK41_RS00580 cf74690672f9dae0a0354da13489e550 464 Pfam PF13416 Bacterial extracellular solute-binding protein 83 386 3.6E-38 T 28-03-2018 CFK41_RS03390 ca5cdd923e3e466354288ec300f85d39 56 Pfam PF13783 Domain of unknown function (DUF4177) 7 40 1.4E-6 T 28-03-2018 IPR025234 Protein of unknown function DUF4177 CFK41_RS02785 e3bdabf4f37034ef16bb0afa7ec81081 502 Gene3D G3DSA:3.50.50.60 10 180 3.3E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS02785 e3bdabf4f37034ef16bb0afa7ec81081 502 PIRSF PIRSF000350 2 492 2.9E-58 T 28-03-2018 CFK41_RS02785 e3bdabf4f37034ef16bb0afa7ec81081 502 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 14 305 2.3E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS02785 e3bdabf4f37034ef16bb0afa7ec81081 502 Gene3D G3DSA:3.30.390.30 394 501 1.1E-30 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CFK41_RS02785 e3bdabf4f37034ef16bb0afa7ec81081 502 SUPERFAMILY SSF55424 382 493 7.04E-29 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CFK41_RS02785 e3bdabf4f37034ef16bb0afa7ec81081 502 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 382 487 2.0E-25 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CFK41_RS02785 e3bdabf4f37034ef16bb0afa7ec81081 502 Gene3D G3DSA:3.50.50.60 184 393 7.5E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS02785 e3bdabf4f37034ef16bb0afa7ec81081 502 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 378 399 8.0E-44 T 28-03-2018 CFK41_RS02785 e3bdabf4f37034ef16bb0afa7ec81081 502 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 47 62 8.0E-44 T 28-03-2018 CFK41_RS02785 e3bdabf4f37034ef16bb0afa7ec81081 502 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 150 159 8.0E-44 T 28-03-2018 CFK41_RS02785 e3bdabf4f37034ef16bb0afa7ec81081 502 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 283 297 8.0E-44 T 28-03-2018 CFK41_RS02785 e3bdabf4f37034ef16bb0afa7ec81081 502 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 337 344 8.0E-44 T 28-03-2018 CFK41_RS02785 e3bdabf4f37034ef16bb0afa7ec81081 502 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 14 36 8.0E-44 T 28-03-2018 CFK41_RS02785 e3bdabf4f37034ef16bb0afa7ec81081 502 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 184 209 8.0E-44 T 28-03-2018 CFK41_RS02785 e3bdabf4f37034ef16bb0afa7ec81081 502 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 444 459 8.0E-44 T 28-03-2018 CFK41_RS02785 e3bdabf4f37034ef16bb0afa7ec81081 502 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 298 2.5E-17 T 28-03-2018 CFK41_RS02785 e3bdabf4f37034ef16bb0afa7ec81081 502 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 2.5E-17 T 28-03-2018 CFK41_RS02785 e3bdabf4f37034ef16bb0afa7ec81081 502 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 15 34 2.5E-17 T 28-03-2018 CFK41_RS02785 e3bdabf4f37034ef16bb0afa7ec81081 502 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 184 202 2.5E-17 T 28-03-2018 CFK41_RS02785 e3bdabf4f37034ef16bb0afa7ec81081 502 SUPERFAMILY SSF51905 10 406 5.59E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS09770 17c835e82482e4612e0f5a59cb6aff2b 141 Gene3D G3DSA:3.40.50.620 1 130 6.3E-18 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS09770 17c835e82482e4612e0f5a59cb6aff2b 141 Pfam PF00582 Universal stress protein family 2 127 4.3E-12 T 28-03-2018 IPR006016 UspA GO:0006950 CFK41_RS09770 17c835e82482e4612e0f5a59cb6aff2b 141 SUPERFAMILY SSF52402 1 130 1.34E-17 T 28-03-2018 CFK41_RS09770 17c835e82482e4612e0f5a59cb6aff2b 141 PRINTS PR01438 Universal stress protein signature 105 127 1.7E-6 T 28-03-2018 IPR006015 Universal stress protein A CFK41_RS09770 17c835e82482e4612e0f5a59cb6aff2b 141 PRINTS PR01438 Universal stress protein signature 87 99 1.7E-6 T 28-03-2018 IPR006015 Universal stress protein A CFK41_RS05600 f329229a49bb4c2e6cb90e7a35a1c075 445 Gene3D G3DSA:3.40.50.1980 241 387 5.6E-58 T 28-03-2018 CFK41_RS05600 f329229a49bb4c2e6cb90e7a35a1c075 445 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 42 442 8.4E-136 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CFK41_RS05600 f329229a49bb4c2e6cb90e7a35a1c075 445 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 244 276 - T 28-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 CFK41_RS05600 f329229a49bb4c2e6cb90e7a35a1c075 445 PIRSF PIRSF000099 7 445 4.0E-144 T 28-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CFK41_RS05600 f329229a49bb4c2e6cb90e7a35a1c075 445 Gene3D G3DSA:3.40.50.1980 33 240 2.9E-79 T 28-03-2018 CFK41_RS05600 f329229a49bb4c2e6cb90e7a35a1c075 445 PRINTS PR00083 Histidinol dehydrogenase signature 336 361 6.1E-69 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CFK41_RS05600 f329229a49bb4c2e6cb90e7a35a1c075 445 PRINTS PR00083 Histidinol dehydrogenase signature 377 395 6.1E-69 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CFK41_RS05600 f329229a49bb4c2e6cb90e7a35a1c075 445 PRINTS PR00083 Histidinol dehydrogenase signature 41 65 6.1E-69 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CFK41_RS05600 f329229a49bb4c2e6cb90e7a35a1c075 445 PRINTS PR00083 Histidinol dehydrogenase signature 142 168 6.1E-69 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CFK41_RS05600 f329229a49bb4c2e6cb90e7a35a1c075 445 PRINTS PR00083 Histidinol dehydrogenase signature 215 240 6.1E-69 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CFK41_RS05600 f329229a49bb4c2e6cb90e7a35a1c075 445 PRINTS PR00083 Histidinol dehydrogenase signature 244 265 6.1E-69 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CFK41_RS05600 f329229a49bb4c2e6cb90e7a35a1c075 445 PRINTS PR00083 Histidinol dehydrogenase signature 266 285 6.1E-69 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CFK41_RS05600 f329229a49bb4c2e6cb90e7a35a1c075 445 SUPERFAMILY SSF53720 33 443 2.75E-64 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CFK41_RS05600 f329229a49bb4c2e6cb90e7a35a1c075 445 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 13 443 37.821 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CFK41_RS05600 f329229a49bb4c2e6cb90e7a35a1c075 445 Pfam PF00815 Histidinol dehydrogenase 28 443 1.3E-148 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CFK41_RS12960 f7c39974c3dc463d1dfeffc5554c5c15 528 Pfam PF02720 Domain of unknown function (DUF222) 93 357 5.2E-13 T 28-03-2018 IPR003870 Domain of unknown function DUF222 CFK41_RS12960 f7c39974c3dc463d1dfeffc5554c5c15 528 Pfam PF01844 HNH endonuclease 432 462 6.0E-5 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CFK41_RS12960 f7c39974c3dc463d1dfeffc5554c5c15 528 Gene3D G3DSA:3.40.1800.10 402 465 6.1E-7 T 28-03-2018 CFK41_RS12960 f7c39974c3dc463d1dfeffc5554c5c15 528 SMART SM00507 409 459 7.3E-4 T 28-03-2018 IPR003615 HNH nuclease CFK41_RS01985 56581bf979fa66b7516b2f33d45c88dd 131 Pfam PF01022 Bacterial regulatory protein, arsR family 56 104 2.4E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS01985 56581bf979fa66b7516b2f33d45c88dd 131 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 86 101 3.3E-19 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS01985 56581bf979fa66b7516b2f33d45c88dd 131 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 101 116 3.3E-19 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS01985 56581bf979fa66b7516b2f33d45c88dd 131 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 73 84 3.3E-19 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS01985 56581bf979fa66b7516b2f33d45c88dd 131 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 51 66 3.3E-19 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS01985 56581bf979fa66b7516b2f33d45c88dd 131 SUPERFAMILY SSF46785 39 128 3.18E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS01985 56581bf979fa66b7516b2f33d45c88dd 131 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 75 93 - T 28-03-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 CFK41_RS01985 56581bf979fa66b7516b2f33d45c88dd 131 Gene3D G3DSA:1.10.10.10 15 130 6.3E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS01985 56581bf979fa66b7516b2f33d45c88dd 131 SMART SM00418 49 130 2.1E-25 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS11085 c3c052a45351b4dee66f6061aab92dc2 206 SUPERFAMILY SSF52833 6 166 4.85E-13 T 28-03-2018 IPR012336 Thioredoxin-like fold CFK41_RS11085 c3c052a45351b4dee66f6061aab92dc2 206 Gene3D G3DSA:3.40.30.10 57 167 1.6E-7 T 28-03-2018 CFK41_RS11085 c3c052a45351b4dee66f6061aab92dc2 206 Gene3D G3DSA:3.40.30.10 3 56 4.3E-6 T 28-03-2018 CFK41_RS04335 2ae7fd8f362805416d1ac46dadae4581 215 Gene3D G3DSA:3.40.50.1240 1 200 6.1E-35 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CFK41_RS04335 2ae7fd8f362805416d1ac46dadae4581 215 SUPERFAMILY SSF53254 3 189 7.07E-38 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CFK41_RS04335 2ae7fd8f362805416d1ac46dadae4581 215 SMART SM00855 5 157 3.4E-14 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CFK41_RS04335 2ae7fd8f362805416d1ac46dadae4581 215 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 187 1.4E-35 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CFK41_RS16785 c35d2241385fb773e1f7ff505b8e0dc7 114 SUPERFAMILY SSF46955 3 107 7.33E-23 T 28-03-2018 IPR009061 Putative DNA-binding domain CFK41_RS16785 c35d2241385fb773e1f7ff505b8e0dc7 114 Gene3D G3DSA:1.10.1660.10 56 114 2.3E-8 T 28-03-2018 CFK41_RS16785 c35d2241385fb773e1f7ff505b8e0dc7 114 Pfam PF13411 MerR HTH family regulatory protein 3 67 1.0E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS16785 c35d2241385fb773e1f7ff505b8e0dc7 114 Gene3D G3DSA:1.10.1660.10 1 55 7.6E-21 T 28-03-2018 CFK41_RS16785 c35d2241385fb773e1f7ff505b8e0dc7 114 SMART SM00422 1 69 5.8E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS16785 c35d2241385fb773e1f7ff505b8e0dc7 114 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 4.0E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS16785 c35d2241385fb773e1f7ff505b8e0dc7 114 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 4.0E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS16785 c35d2241385fb773e1f7ff505b8e0dc7 114 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 4.0E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS02885 298a60b9fb724e8787e4b37b9b3bbdfc 330 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 74 132 2.7E-12 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CFK41_RS02885 298a60b9fb724e8787e4b37b9b3bbdfc 330 Gene3D G3DSA:1.10.3720.10 68 292 2.4E-41 T 28-03-2018 CFK41_RS02885 298a60b9fb724e8787e4b37b9b3bbdfc 330 SUPERFAMILY SSF161098 75 278 2.75E-39 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS02885 298a60b9fb724e8787e4b37b9b3bbdfc 330 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 291 3.3E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS10190 29b90de0ac9602a817dae99bfdc46975 154 Pfam PF04977 Septum formation initiator 8 84 4.2E-16 T 28-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 CFK41_RS10190 29b90de0ac9602a817dae99bfdc46975 154 Gene3D G3DSA:1.20.5.50 22 59 2.5E-4 T 28-03-2018 CFK41_RS11210 474a143704a8e8fc40de9a6ac5ce0531 97 Pfam PF02467 Transcription factor WhiB 21 71 3.4E-14 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain CFK41_RS11210 474a143704a8e8fc40de9a6ac5ce0531 97 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 88 13.884 T 28-03-2018 IPR003482 Transcription factor WhiB CFK41_RS01930 8918d737cf385e075b597a8cfa21f39b 35 Pfam PF16951 Putative methionine and alanine importer, small subunit 1 33 7.0E-11 T 28-03-2018 IPR031596 Putative methionine and alanine importer, small subunit CFK41_RS04125 ad88cd434f1cb247bef2e4879740cd18 275 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 125 142 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CFK41_RS04125 ad88cd434f1cb247bef2e4879740cd18 275 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 41 58 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CFK41_RS04125 ad88cd434f1cb247bef2e4879740cd18 275 PIRSF PIRSF000097 1 271 4.6E-78 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS04125 ad88cd434f1cb247bef2e4879740cd18 275 PRINTS PR00069 Aldo-keto reductase signature 196 220 5.7E-38 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS04125 ad88cd434f1cb247bef2e4879740cd18 275 PRINTS PR00069 Aldo-keto reductase signature 93 111 5.7E-38 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS04125 ad88cd434f1cb247bef2e4879740cd18 275 PRINTS PR00069 Aldo-keto reductase signature 125 142 5.7E-38 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS04125 ad88cd434f1cb247bef2e4879740cd18 275 PRINTS PR00069 Aldo-keto reductase signature 159 188 5.7E-38 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS04125 ad88cd434f1cb247bef2e4879740cd18 275 PRINTS PR00069 Aldo-keto reductase signature 37 61 5.7E-38 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS04125 ad88cd434f1cb247bef2e4879740cd18 275 Pfam PF00248 Aldo/keto reductase family 24 197 3.5E-37 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS04125 ad88cd434f1cb247bef2e4879740cd18 275 Pfam PF00248 Aldo/keto reductase family 203 261 5.4E-11 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS04125 ad88cd434f1cb247bef2e4879740cd18 275 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 229 244 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CFK41_RS04125 ad88cd434f1cb247bef2e4879740cd18 275 SUPERFAMILY SSF51430 6 267 1.83E-91 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS04125 ad88cd434f1cb247bef2e4879740cd18 275 Gene3D G3DSA:3.20.20.100 3 271 5.0E-92 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS16245 07a5f52ce74f8a097ccee61132a062db 311 Pfam PF00248 Aldo/keto reductase family 16 302 1.4E-50 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS16245 07a5f52ce74f8a097ccee61132a062db 311 Gene3D G3DSA:3.20.20.100 1 307 3.5E-69 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS16245 07a5f52ce74f8a097ccee61132a062db 311 SUPERFAMILY SSF51430 1 306 1.05E-68 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS15870 f9970d4c5234edd961982388fa6afd8c 192 Gene3D G3DSA:1.10.10.60 2 40 4.8E-13 T 28-03-2018 CFK41_RS15870 f9970d4c5234edd961982388fa6afd8c 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 7.7E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS15870 f9970d4c5234edd961982388fa6afd8c 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 7.7E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS15870 f9970d4c5234edd961982388fa6afd8c 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 51 9.5E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS15870 f9970d4c5234edd961982388fa6afd8c 192 SUPERFAMILY SSF46689 4 72 2.21E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS15870 f9970d4c5234edd961982388fa6afd8c 192 Gene3D G3DSA:1.10.10.60 41 189 1.7E-9 T 28-03-2018 CFK41_RS10635 6db72c96faf09a19e40dcce3d3292125 311 Pfam PF03547 Membrane transport protein 11 142 8.2E-7 T 28-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CFK41_RS10635 6db72c96faf09a19e40dcce3d3292125 311 Pfam PF03547 Membrane transport protein 160 305 4.6E-18 T 28-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CFK41_RS00110 c6573a78204c2f97b9b81ed9240549a2 327 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 12 309 2.4E-13 T 28-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 CFK41_RS00110 c6573a78204c2f97b9b81ed9240549a2 327 Gene3D G3DSA:3.30.420.40 141 285 2.4E-15 T 28-03-2018 CFK41_RS00110 c6573a78204c2f97b9b81ed9240549a2 327 Gene3D G3DSA:3.30.420.40 1 140 4.8E-20 T 28-03-2018 CFK41_RS00110 c6573a78204c2f97b9b81ed9240549a2 327 SUPERFAMILY SSF53067 9 122 1.4E-15 T 28-03-2018 CFK41_RS00110 c6573a78204c2f97b9b81ed9240549a2 327 SUPERFAMILY SSF53067 126 322 3.13E-19 T 28-03-2018 CFK41_RS12420 c142970dcbdd94df346c33ad591d2f42 72 SUPERFAMILY SSF46955 18 66 3.62E-12 T 28-03-2018 IPR009061 Putative DNA-binding domain CFK41_RS12420 c142970dcbdd94df346c33ad591d2f42 72 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 18 65 1.9E-9 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CFK41_RS12420 c142970dcbdd94df346c33ad591d2f42 72 Gene3D G3DSA:1.10.10.60 12 32 0.096 T 28-03-2018 CFK41_RS12420 c142970dcbdd94df346c33ad591d2f42 72 Gene3D G3DSA:1.10.10.10 33 71 6.5E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS12420 c142970dcbdd94df346c33ad591d2f42 72 Pfam PF12728 Helix-turn-helix domain 18 66 7.4E-13 T 28-03-2018 CFK41_RS11840 971e577416e6a2635b1a0e5669f1aed0 274 Pfam PF00889 Elongation factor TS 75 274 1.5E-60 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CFK41_RS11840 971e577416e6a2635b1a0e5669f1aed0 274 Gene3D G3DSA:1.10.8.10 1 56 1.9E-17 T 28-03-2018 CFK41_RS11840 971e577416e6a2635b1a0e5669f1aed0 274 ProSitePatterns PS01127 Elongation factor Ts signature 2. 79 89 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CFK41_RS11840 971e577416e6a2635b1a0e5669f1aed0 274 Gene3D G3DSA:3.30.479.20 58 152 1.8E-15 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CFK41_RS11840 971e577416e6a2635b1a0e5669f1aed0 274 SUPERFAMILY SSF46934 3 55 8.06E-13 T 28-03-2018 IPR009060 UBA-like GO:0005515 CFK41_RS11840 971e577416e6a2635b1a0e5669f1aed0 274 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 273 4.0E-73 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CFK41_RS11840 971e577416e6a2635b1a0e5669f1aed0 274 SUPERFAMILY SSF54713 57 96 3.76E-43 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CFK41_RS11840 971e577416e6a2635b1a0e5669f1aed0 274 SUPERFAMILY SSF54713 177 273 3.76E-43 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CFK41_RS11840 971e577416e6a2635b1a0e5669f1aed0 274 Gene3D G3DSA:3.30.479.20 226 273 8.0E-11 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CFK41_RS11840 971e577416e6a2635b1a0e5669f1aed0 274 Gene3D G3DSA:3.30.479.20 153 205 1.1E-8 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CFK41_RS11840 971e577416e6a2635b1a0e5669f1aed0 274 Gene3D G3DSA:1.10.286.20 206 225 6.1E-17 T 28-03-2018 CFK41_RS11840 971e577416e6a2635b1a0e5669f1aed0 274 Hamap MF_00050 Elongation factor Ts [tsf]. 1 274 61.95 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CFK41_RS11615 173bbd947e3b37990f7bafba505838b3 325 Gene3D G3DSA:3.40.50.300 14 204 9.8E-63 T 28-03-2018 CFK41_RS11615 173bbd947e3b37990f7bafba505838b3 325 Pfam PF01715 IPP transferase 51 293 3.5E-73 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CFK41_RS11615 173bbd947e3b37990f7bafba505838b3 325 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 18 318 28.035 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CFK41_RS11615 173bbd947e3b37990f7bafba505838b3 325 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 19 300 1.3E-78 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CFK41_RS11615 173bbd947e3b37990f7bafba505838b3 325 SUPERFAMILY SSF52540 18 151 7.08E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11615 173bbd947e3b37990f7bafba505838b3 325 Gene3D G3DSA:1.10.287.890 210 290 6.7E-21 T 28-03-2018 CFK41_RS13830 77c4b798656253e7780da33dedf449bf 162 PIRSF PIRSF000303 1 161 3.6E-57 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CFK41_RS13830 77c4b798656253e7780da33dedf449bf 162 Pfam PF00255 Glutathione peroxidase 6 111 4.7E-35 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CFK41_RS13830 77c4b798656253e7780da33dedf449bf 162 PRINTS PR01011 Glutathione peroxidase family signature 123 132 8.9E-12 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CFK41_RS13830 77c4b798656253e7780da33dedf449bf 162 PRINTS PR01011 Glutathione peroxidase family signature 59 75 8.9E-12 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CFK41_RS13830 77c4b798656253e7780da33dedf449bf 162 PRINTS PR01011 Glutathione peroxidase family signature 24 41 8.9E-12 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CFK41_RS13830 77c4b798656253e7780da33dedf449bf 162 SUPERFAMILY SSF52833 5 159 1.37E-50 T 28-03-2018 IPR012336 Thioredoxin-like fold CFK41_RS13830 77c4b798656253e7780da33dedf449bf 162 Gene3D G3DSA:3.40.30.10 4 161 1.7E-39 T 28-03-2018 CFK41_RS05450 b15e1e4b1d3fe16daac23718c706d6c7 345 Gene3D G3DSA:1.10.3470.10 16 345 8.3E-62 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CFK41_RS05450 b15e1e4b1d3fe16daac23718c706d6c7 345 Pfam PF01032 FecCD transport family 33 336 4.7E-73 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CFK41_RS05450 b15e1e4b1d3fe16daac23718c706d6c7 345 SUPERFAMILY SSF81345 13 336 8.76E-64 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CFK41_RS08320 8895244e7645da9b37733b8a43cf40cf 325 Pfam PF05235 CHAD domain 82 287 1.4E-32 T 28-03-2018 IPR007899 CHAD domain CFK41_RS08320 8895244e7645da9b37733b8a43cf40cf 325 SMART SM00880 57 319 2.6E-31 T 28-03-2018 IPR007899 CHAD domain CFK41_RS16775 4557f7a77baca486ef2ca8bf24e200b5 305 Pfam PF02517 CAAX protease self-immunity 157 250 7.6E-10 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CFK41_RS01655 3f1065378640d05e009809afa1f65aaf 171 PRINTS PR00070 Dihydrofolate reductase signature 31 39 2.3E-15 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CFK41_RS01655 3f1065378640d05e009809afa1f65aaf 171 PRINTS PR00070 Dihydrofolate reductase signature 17 27 2.3E-15 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CFK41_RS01655 3f1065378640d05e009809afa1f65aaf 171 PRINTS PR00070 Dihydrofolate reductase signature 44 55 2.3E-15 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CFK41_RS01655 3f1065378640d05e009809afa1f65aaf 171 PRINTS PR00070 Dihydrofolate reductase signature 102 116 2.3E-15 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CFK41_RS01655 3f1065378640d05e009809afa1f65aaf 171 SUPERFAMILY SSF53597 5 171 7.55E-51 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CFK41_RS01655 3f1065378640d05e009809afa1f65aaf 171 Pfam PF00186 Dihydrofolate reductase 6 171 8.1E-49 T 28-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CFK41_RS01655 3f1065378640d05e009809afa1f65aaf 171 Gene3D G3DSA:3.40.430.10 41 171 3.5E-37 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CFK41_RS01655 3f1065378640d05e009809afa1f65aaf 171 Gene3D G3DSA:3.40.430.10 1 40 3.8E-13 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CFK41_RS01655 3f1065378640d05e009809afa1f65aaf 171 PIRSF PIRSF000194 1 171 2.0E-52 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CFK41_RS01655 3f1065378640d05e009809afa1f65aaf 171 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 17 39 - T 28-03-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 CFK41_RS12885 413ff318ed68f63a3c4c77961f4955c0 467 SUPERFAMILY SSF103473 16 412 2.09E-47 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS12885 413ff318ed68f63a3c4c77961f4955c0 467 Gene3D G3DSA:1.20.1250.20 225 432 2.5E-18 T 28-03-2018 CFK41_RS12885 413ff318ed68f63a3c4c77961f4955c0 467 Gene3D G3DSA:1.20.1250.20 19 224 1.4E-18 T 28-03-2018 CFK41_RS12885 413ff318ed68f63a3c4c77961f4955c0 467 Pfam PF07690 Major Facilitator Superfamily 41 353 1.1E-22 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS12415 9ce3741561d20212f6d896fb9231a838 355 SUPERFAMILY SSF53474 48 321 5.07E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS12415 9ce3741561d20212f6d896fb9231a838 355 Gene3D G3DSA:3.40.50.1820 47 322 6.2E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS12415 9ce3741561d20212f6d896fb9231a838 355 Pfam PF12146 Serine aminopeptidase, S33 54 302 1.7E-19 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CFK41_RS06230 47799d95b30c7fc7f0e87c7b22f1b89a 385 Pfam PF13450 NAD(P)-binding Rossmann-like domain 8 77 3.7E-18 T 28-03-2018 CFK41_RS06230 47799d95b30c7fc7f0e87c7b22f1b89a 385 Pfam PF03275 UDP-galactopyranose mutase 152 361 3.2E-79 T 28-03-2018 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 CFK41_RS06230 47799d95b30c7fc7f0e87c7b22f1b89a 385 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 5 379 1.2E-101 T 28-03-2018 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 CFK41_RS06230 47799d95b30c7fc7f0e87c7b22f1b89a 385 SUPERFAMILY SSF54373 257 328 4.51E-21 T 28-03-2018 CFK41_RS06230 47799d95b30c7fc7f0e87c7b22f1b89a 385 SUPERFAMILY SSF51971 346 377 1.29E-42 T 28-03-2018 CFK41_RS06230 47799d95b30c7fc7f0e87c7b22f1b89a 385 SUPERFAMILY SSF51971 4 276 1.29E-42 T 28-03-2018 CFK41_RS06230 47799d95b30c7fc7f0e87c7b22f1b89a 385 Gene3D G3DSA:3.40.50.720 2 293 1.8E-36 T 28-03-2018 CFK41_RS06230 47799d95b30c7fc7f0e87c7b22f1b89a 385 Gene3D G3DSA:3.40.50.720 294 382 2.2E-9 T 28-03-2018 CFK41_RS07700 13ecfec4d793954708ef3e2baf3f4fb6 502 Pfam PF04230 Polysaccharide pyruvyl transferase 93 300 8.7E-17 T 28-03-2018 IPR007345 Polysaccharide pyruvyl transferase CFK41_RS07700 13ecfec4d793954708ef3e2baf3f4fb6 502 Gene3D G3DSA:1.20.1000.10 17 494 9.6E-8 T 28-03-2018 CFK41_RS14590 2cb9aa9b7d3cfce86f65a9b861108b2b 133 Pfam PF01042 Endoribonuclease L-PSP 17 130 2.7E-32 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family CFK41_RS14590 2cb9aa9b7d3cfce86f65a9b861108b2b 133 Gene3D G3DSA:3.30.1330.40 12 133 3.6E-38 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CFK41_RS14590 2cb9aa9b7d3cfce86f65a9b861108b2b 133 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 11 129 1.2E-33 T 28-03-2018 IPR006056 RidA family CFK41_RS14590 2cb9aa9b7d3cfce86f65a9b861108b2b 133 SUPERFAMILY SSF55298 10 131 1.4E-37 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CFK41_RS08275 ae4c9193280833256f366f3c4e673b9f 335 Gene3D G3DSA:3.40.50.1980 40 217 5.9E-39 T 28-03-2018 CFK41_RS08275 ae4c9193280833256f366f3c4e673b9f 335 Pfam PF01297 Zinc-uptake complex component A periplasmic 43 331 2.6E-62 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CFK41_RS08275 ae4c9193280833256f366f3c4e673b9f 335 SUPERFAMILY SSF53807 40 332 1.47E-67 T 28-03-2018 CFK41_RS08275 ae4c9193280833256f366f3c4e673b9f 335 Gene3D G3DSA:3.40.50.1980 218 333 5.2E-33 T 28-03-2018 CFK41_RS16665 ca292ca9bcce9ff3c31d0b7f42694116 252 Gene3D G3DSA:3.40.50.1400 111 234 2.2E-19 T 28-03-2018 CFK41_RS16665 ca292ca9bcce9ff3c31d0b7f42694116 252 Pfam PF01903 CbiX 131 196 1.6E-6 T 28-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CFK41_RS16665 ca292ca9bcce9ff3c31d0b7f42694116 252 Pfam PF01903 CbiX 9 106 1.6E-11 T 28-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CFK41_RS16665 ca292ca9bcce9ff3c31d0b7f42694116 252 Gene3D G3DSA:3.40.50.1400 1 110 1.4E-19 T 28-03-2018 CFK41_RS16665 ca292ca9bcce9ff3c31d0b7f42694116 252 SUPERFAMILY SSF53800 1 229 6.54E-28 T 28-03-2018 CFK41_RS14595 5224904c31557aae350fb226c466a36a 539 Pfam PF07969 Amidohydrolase family 46 504 8.3E-25 T 28-03-2018 IPR013108 Amidohydrolase 3 CFK41_RS14595 5224904c31557aae350fb226c466a36a 539 Gene3D G3DSA:2.30.40.10 441 513 1.4E-4 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS14595 5224904c31557aae350fb226c466a36a 539 SUPERFAMILY SSF51338 1 75 2.81E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS14595 5224904c31557aae350fb226c466a36a 539 Gene3D G3DSA:3.20.20.140 68 440 3.9E-58 T 28-03-2018 CFK41_RS14595 5224904c31557aae350fb226c466a36a 539 SUPERFAMILY SSF51338 461 519 7.56E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS14595 5224904c31557aae350fb226c466a36a 539 Gene3D G3DSA:2.30.40.10 3 67 9.7E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS14595 5224904c31557aae350fb226c466a36a 539 SUPERFAMILY SSF51556 326 460 3.4E-55 T 28-03-2018 IPR032466 Metal-dependent hydrolase CFK41_RS14595 5224904c31557aae350fb226c466a36a 539 SUPERFAMILY SSF51556 57 283 3.4E-55 T 28-03-2018 IPR032466 Metal-dependent hydrolase CFK41_RS05720 ef6a51c8ecb423efe8f59dd95dc76d5d 206 SUPERFAMILY SSF56281 20 206 4.72E-45 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS05720 ef6a51c8ecb423efe8f59dd95dc76d5d 206 Gene3D G3DSA:3.60.15.10 15 203 2.9E-35 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS05720 ef6a51c8ecb423efe8f59dd95dc76d5d 206 Pfam PF00753 Metallo-beta-lactamase superfamily 25 188 2.5E-21 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS05720 ef6a51c8ecb423efe8f59dd95dc76d5d 206 SMART SM00849 24 188 4.5E-36 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS09110 8f2695a2652e870ac9928eefbe59a8a8 298 Pfam PF00551 Formyl transferase 102 278 7.4E-34 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CFK41_RS09110 8f2695a2652e870ac9928eefbe59a8a8 298 SUPERFAMILY SSF53328 102 297 1.28E-55 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CFK41_RS09110 8f2695a2652e870ac9928eefbe59a8a8 298 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 18 297 40.496 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CFK41_RS09110 8f2695a2652e870ac9928eefbe59a8a8 298 Gene3D G3DSA:3.40.50.170 101 298 2.7E-51 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CFK41_RS09110 8f2695a2652e870ac9928eefbe59a8a8 298 SUPERFAMILY SSF55021 20 96 5.83E-13 T 28-03-2018 CFK41_RS09110 8f2695a2652e870ac9928eefbe59a8a8 298 PIRSF PIRSF036480 18 298 3.2E-90 T 28-03-2018 CFK41_RS09110 8f2695a2652e870ac9928eefbe59a8a8 298 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 102 124 4.8E-38 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CFK41_RS09110 8f2695a2652e870ac9928eefbe59a8a8 298 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 23 49 4.8E-38 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CFK41_RS09110 8f2695a2652e870ac9928eefbe59a8a8 298 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 55 67 4.8E-38 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CFK41_RS09110 8f2695a2652e870ac9928eefbe59a8a8 298 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 271 296 4.8E-38 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CFK41_RS09110 8f2695a2652e870ac9928eefbe59a8a8 298 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 124 151 4.8E-38 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CFK41_RS09110 8f2695a2652e870ac9928eefbe59a8a8 298 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 249 271 4.8E-38 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CFK41_RS09110 8f2695a2652e870ac9928eefbe59a8a8 298 Gene3D G3DSA:3.30.70.260 11 99 9.1E-18 T 28-03-2018 CFK41_RS10085 7b4b5004398e2ab0b59f77bbbb69cd61 366 Pfam PF13692 Glycosyl transferases group 1 196 324 1.7E-25 T 28-03-2018 CFK41_RS10085 7b4b5004398e2ab0b59f77bbbb69cd61 366 SUPERFAMILY SSF53756 1 358 1.61E-50 T 28-03-2018 CFK41_RS10085 7b4b5004398e2ab0b59f77bbbb69cd61 366 Pfam PF13439 Glycosyltransferase Family 4 27 153 8.1E-9 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CFK41_RS10085 7b4b5004398e2ab0b59f77bbbb69cd61 366 Gene3D G3DSA:3.40.50.2000 192 352 1.9E-31 T 28-03-2018 CFK41_RS10885 c3e25bdefda171d58626f9db50d85095 418 Gene3D G3DSA:3.10.28.20 307 393 2.5E-14 T 28-03-2018 CFK41_RS10885 c3e25bdefda171d58626f9db50d85095 418 SUPERFAMILY SSF141130 21 173 5.23E-72 T 28-03-2018 CFK41_RS10885 c3e25bdefda171d58626f9db50d85095 418 SUPERFAMILY SSF141130 222 393 5.23E-72 T 28-03-2018 CFK41_RS10885 c3e25bdefda171d58626f9db50d85095 418 Pfam PF03069 Acetamidase/Formamidase family 9 393 3.1E-161 T 28-03-2018 IPR004304 Acetamidase/Formamidase GO:0016811 CFK41_RS10885 c3e25bdefda171d58626f9db50d85095 418 Gene3D G3DSA:2.60.120.580 159 289 8.3E-30 T 28-03-2018 CFK41_RS10885 c3e25bdefda171d58626f9db50d85095 418 Gene3D G3DSA:2.60.120.580 9 158 2.2E-31 T 28-03-2018 CFK41_RS07770 20968c2b6ed1867301932011875ce75f 261 Gene3D G3DSA:3.40.190.10 33 260 4.8E-5 T 28-03-2018 CFK41_RS09095 5ef25bce9c8abd5fd39c517a9ca8f090 419 Gene3D G3DSA:3.90.1150.10 305 415 1.1E-20 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS09095 5ef25bce9c8abd5fd39c517a9ca8f090 419 Pfam PF00202 Aminotransferase class-III 23 412 1.3E-76 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CFK41_RS09095 5ef25bce9c8abd5fd39c517a9ca8f090 419 PIRSF PIRSF000521 25 130 6.0E-4 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CFK41_RS09095 5ef25bce9c8abd5fd39c517a9ca8f090 419 PIRSF PIRSF000521 123 415 3.1E-34 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CFK41_RS09095 5ef25bce9c8abd5fd39c517a9ca8f090 419 Gene3D G3DSA:3.90.1150.10 3 165 7.4E-34 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS09095 5ef25bce9c8abd5fd39c517a9ca8f090 419 Gene3D G3DSA:3.40.640.10 179 304 1.6E-27 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS09095 5ef25bce9c8abd5fd39c517a9ca8f090 419 SUPERFAMILY SSF53383 8 413 4.03E-105 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS09095 5ef25bce9c8abd5fd39c517a9ca8f090 419 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 233 269 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CFK41_RS16625 a0d8b2ba0f3b14626341dff749964f04 224 SMART SM01120 38 211 1.2E-48 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CFK41_RS16625 a0d8b2ba0f3b14626341dff749964f04 224 SUPERFAMILY SSF101473 15 210 1.96E-41 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CFK41_RS16625 a0d8b2ba0f3b14626341dff749964f04 224 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 17 208 4.4E-42 T 28-03-2018 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 CFK41_RS16625 a0d8b2ba0f3b14626341dff749964f04 224 Pfam PF02734 DAK2 domain 39 209 1.8E-43 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CFK41_RS06715 051792e160df7db44784d0c1a05e184f 237 Gene3D G3DSA:1.10.260.40 63 87 7.5E-10 T 28-03-2018 CFK41_RS06715 051792e160df7db44784d0c1a05e184f 237 Gene3D G3DSA:1.10.10.60 13 62 3.4E-14 T 28-03-2018 CFK41_RS06715 051792e160df7db44784d0c1a05e184f 237 SUPERFAMILY SSF46689 33 102 2.28E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS06715 051792e160df7db44784d0c1a05e184f 237 Gene3D G3DSA:1.10.357.10 88 225 9.5E-8 T 28-03-2018 CFK41_RS06715 051792e160df7db44784d0c1a05e184f 237 Pfam PF00440 Bacterial regulatory proteins, tetR family 41 85 8.3E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS06715 051792e160df7db44784d0c1a05e184f 237 SUPERFAMILY SSF48498 129 202 7.41E-5 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CFK41_RS06715 051792e160df7db44784d0c1a05e184f 237 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 62 85 1.7E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS06715 051792e160df7db44784d0c1a05e184f 237 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 54 1.7E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS13760 e89b5868fcee2a87a1fc8749d24d31a6 243 SUPERFAMILY SSF54593 134 238 5.82E-8 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS13760 e89b5868fcee2a87a1fc8749d24d31a6 243 Gene3D G3DSA:3.10.180.10 3 126 1.5E-9 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS13760 e89b5868fcee2a87a1fc8749d24d31a6 243 Gene3D G3DSA:3.10.180.10 127 237 3.2E-9 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS13760 e89b5868fcee2a87a1fc8749d24d31a6 243 SUPERFAMILY SSF54593 10 142 4.29E-6 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS04070 e01a4eaf28ab7044d7c4aa7351f5faec 58 Gene3D G3DSA:3.40.50.850 1 58 1.4E-7 T 28-03-2018 CFK41_RS04070 e01a4eaf28ab7044d7c4aa7351f5faec 58 Pfam PF00857 Isochorismatase family 2 50 4.5E-6 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CFK41_RS04070 e01a4eaf28ab7044d7c4aa7351f5faec 58 SUPERFAMILY SSF52499 2 56 4.06E-9 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CFK41_RS08855 df9eba0e74ee52e4d1f5ab2d367be9fa 247 Gene3D G3DSA:3.40.50.150 2 247 1.1E-23 T 28-03-2018 CFK41_RS08855 df9eba0e74ee52e4d1f5ab2d367be9fa 247 Pfam PF13649 Methyltransferase domain 56 145 1.2E-10 T 28-03-2018 CFK41_RS08855 df9eba0e74ee52e4d1f5ab2d367be9fa 247 SUPERFAMILY SSF53335 7 219 5.02E-25 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS00990 9dddb78d1b60e908e044d80d55a0af7a 160 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 22 159 1.2E-18 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CFK41_RS00990 9dddb78d1b60e908e044d80d55a0af7a 160 Gene3D G3DSA:3.30.530.20 1 160 1.8E-26 T 28-03-2018 IPR023393 START-like domain CFK41_RS00990 9dddb78d1b60e908e044d80d55a0af7a 160 SUPERFAMILY SSF55961 14 159 1.28E-30 T 28-03-2018 CFK41_RS07220 3c80dbb7e58eea77981fd4952845c07f 442 Gene3D G3DSA:3.50.50.60 215 425 1.2E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS07220 3c80dbb7e58eea77981fd4952845c07f 442 SUPERFAMILY SSF51905 5 255 4.23E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS07220 3c80dbb7e58eea77981fd4952845c07f 442 Gene3D G3DSA:3.50.50.60 1 214 7.1E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS07220 3c80dbb7e58eea77981fd4952845c07f 442 SUPERFAMILY SSF51905 150 413 2.37E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS07220 3c80dbb7e58eea77981fd4952845c07f 442 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 7 352 8.7E-102 T 28-03-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase CFK41_RS13415 6eccbab1fa101a7f4af8a0fbadf27293 199 Pfam PF00574 Clp protease 16 193 4.3E-50 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CFK41_RS13415 6eccbab1fa101a7f4af8a0fbadf27293 199 Gene3D G3DSA:3.90.226.10 4 197 3.5E-30 T 28-03-2018 CFK41_RS13415 6eccbab1fa101a7f4af8a0fbadf27293 199 SUPERFAMILY SSF52096 13 193 1.69E-41 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CFK41_RS13415 6eccbab1fa101a7f4af8a0fbadf27293 199 PRINTS PR00127 Clp protease catalytic subunit P signature 93 110 4.1E-25 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CFK41_RS13415 6eccbab1fa101a7f4af8a0fbadf27293 199 PRINTS PR00127 Clp protease catalytic subunit P signature 22 37 4.1E-25 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CFK41_RS13415 6eccbab1fa101a7f4af8a0fbadf27293 199 PRINTS PR00127 Clp protease catalytic subunit P signature 171 190 4.1E-25 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CFK41_RS13415 6eccbab1fa101a7f4af8a0fbadf27293 199 PRINTS PR00127 Clp protease catalytic subunit P signature 62 82 4.1E-25 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CFK41_RS13415 6eccbab1fa101a7f4af8a0fbadf27293 199 PRINTS PR00127 Clp protease catalytic subunit P signature 114 133 4.1E-25 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CFK41_RS05215 70c49d9f4d702b586e88b744e8535c96 135 SUPERFAMILY SSF55729 1 133 6.35E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS05215 70c49d9f4d702b586e88b744e8535c96 135 Gene3D G3DSA:3.40.630.30 72 135 8.9E-14 T 28-03-2018 CFK41_RS05215 70c49d9f4d702b586e88b744e8535c96 135 Gene3D G3DSA:3.40.630.30 1 71 9.7E-17 T 28-03-2018 CFK41_RS05215 70c49d9f4d702b586e88b744e8535c96 135 Pfam PF00583 Acetyltransferase (GNAT) family 30 122 2.4E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS06010 5c904036489d1738dc920e464b64353c 385 Pfam PF00483 Nucleotidyl transferase 8 293 2.7E-46 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CFK41_RS06010 5c904036489d1738dc920e464b64353c 385 SUPERFAMILY SSF159283 325 377 3.66E-8 T 28-03-2018 CFK41_RS06010 5c904036489d1738dc920e464b64353c 385 SUPERFAMILY SSF53448 7 292 1.43E-58 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS06010 5c904036489d1738dc920e464b64353c 385 Gene3D G3DSA:3.90.550.10 6 380 1.1E-78 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS04100 46d7b509a4c5a850a50232299ade7026 154 Pfam PF00583 Acetyltransferase (GNAT) family 44 142 1.2E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS04100 46d7b509a4c5a850a50232299ade7026 154 Gene3D G3DSA:3.40.630.30 10 153 1.2E-24 T 28-03-2018 CFK41_RS04100 46d7b509a4c5a850a50232299ade7026 154 SUPERFAMILY SSF55729 9 147 1.45E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS11765 5ba25746e05c983ac03ae514d1efa63c 373 Pfam PF14530 Domain of unknown function (DUF4439) 243 361 7.9E-9 T 28-03-2018 IPR029447 Domain of unknown function DUF4439 CFK41_RS11765 5ba25746e05c983ac03ae514d1efa63c 373 SUPERFAMILY SSF47240 242 362 7.7E-6 T 28-03-2018 IPR009078 Ferritin-like superfamily CFK41_RS15230 9854f4fae1e962729418e91957d93f59 279 SUPERFAMILY SSF161098 8 279 2.71E-68 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS15230 9854f4fae1e962729418e91957d93f59 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 267 2.4E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS15230 9854f4fae1e962729418e91957d93f59 279 Gene3D G3DSA:1.10.3720.10 1 267 1.5E-45 T 28-03-2018 CFK41_RS06250 baafb205fd60c888fdbfc8fd6b4151ea 239 SUPERFAMILY SSF56801 10 157 5.95E-5 T 28-03-2018 CFK41_RS06250 baafb205fd60c888fdbfc8fd6b4151ea 239 Gene3D G3DSA:3.40.50.980 9 194 4.6E-5 T 28-03-2018 CFK41_RS06220 17505ee6170bf2dab0906636aad5a595 335 Gene3D G3DSA:3.90.550.10 5 284 2.2E-31 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS06220 17505ee6170bf2dab0906636aad5a595 335 Pfam PF00535 Glycosyl transferase family 2 28 157 2.2E-23 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CFK41_RS06220 17505ee6170bf2dab0906636aad5a595 335 SUPERFAMILY SSF53448 24 263 2.32E-39 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS11110 9bb9cc70bf5599282f8f043f97e1f999 232 SMART SM00421 165 222 3.9E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS11110 9bb9cc70bf5599282f8f043f97e1f999 232 SUPERFAMILY SSF52172 14 145 1.25E-32 T 28-03-2018 IPR011006 CheY-like superfamily CFK41_RS11110 9bb9cc70bf5599282f8f043f97e1f999 232 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 182 3.7E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS11110 9bb9cc70bf5599282f8f043f97e1f999 232 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 198 210 3.7E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS11110 9bb9cc70bf5599282f8f043f97e1f999 232 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 198 3.7E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS11110 9bb9cc70bf5599282f8f043f97e1f999 232 Pfam PF00196 Bacterial regulatory proteins, luxR family 167 221 4.1E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS11110 9bb9cc70bf5599282f8f043f97e1f999 232 Pfam PF00072 Response regulator receiver domain 17 130 6.6E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS11110 9bb9cc70bf5599282f8f043f97e1f999 232 ProSitePatterns PS00622 LuxR-type HTH domain signature. 182 209 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS11110 9bb9cc70bf5599282f8f043f97e1f999 232 SMART SM00448 15 129 2.1E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS11110 9bb9cc70bf5599282f8f043f97e1f999 232 Gene3D G3DSA:1.10.10.10 141 231 1.9E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS11110 9bb9cc70bf5599282f8f043f97e1f999 232 SUPERFAMILY SSF46894 151 228 8.16E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CFK41_RS11110 9bb9cc70bf5599282f8f043f97e1f999 232 Gene3D G3DSA:3.40.50.2300 14 140 7.1E-33 T 28-03-2018 CFK41_RS16475 b489bf2e8df10a99f89f3f0b1e47c4ea 252 SUPERFAMILY SSF52317 6 236 3.89E-39 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS16475 b489bf2e8df10a99f89f3f0b1e47c4ea 252 Pfam PF06283 Trehalose utilisation 8 230 3.5E-39 T 28-03-2018 IPR029010 ThuA-like domain CFK41_RS16475 b489bf2e8df10a99f89f3f0b1e47c4ea 252 Gene3D G3DSA:3.40.50.880 10 250 2.8E-33 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS00240 a165c1dcb84e0ee409810b7b164e9874 384 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 67 221 1.0E-36 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CFK41_RS00240 a165c1dcb84e0ee409810b7b164e9874 384 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 67 220 1.7E-37 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CFK41_RS16940 3f289814d7b95e90ce2dc9c78e1cb8af 499 SUPERFAMILY SSF53720 4 483 7.85E-143 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CFK41_RS16940 3f289814d7b95e90ce2dc9c78e1cb8af 499 Gene3D G3DSA:3.40.605.10 1 265 3.1E-82 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CFK41_RS16940 3f289814d7b95e90ce2dc9c78e1cb8af 499 Pfam PF00171 Aldehyde dehydrogenase family 20 478 1.1E-133 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CFK41_RS16940 3f289814d7b95e90ce2dc9c78e1cb8af 499 Gene3D G3DSA:3.40.309.10 266 461 9.5E-60 T 28-03-2018 CFK41_RS16940 3f289814d7b95e90ce2dc9c78e1cb8af 499 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 5 482 3.3E-191 T 28-03-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 CFK41_RS05460 239d96834955c7d91091c83ba61f5d3e 349 Gene3D G3DSA:3.40.50.1980 175 349 2.3E-22 T 28-03-2018 CFK41_RS05460 239d96834955c7d91091c83ba61f5d3e 349 Gene3D G3DSA:3.40.50.1980 48 174 4.4E-22 T 28-03-2018 CFK41_RS05460 239d96834955c7d91091c83ba61f5d3e 349 SUPERFAMILY SSF53807 48 320 2.83E-42 T 28-03-2018 CFK41_RS05460 239d96834955c7d91091c83ba61f5d3e 349 Pfam PF01497 Periplasmic binding protein 69 315 1.0E-30 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CFK41_RS04625 40bab20479bc283b177c05365614b1a6 565 ProSitePatterns PS00217 Sugar transport proteins signature 2. 156 181 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CFK41_RS04625 40bab20479bc283b177c05365614b1a6 565 ProSitePatterns PS00216 Sugar transport proteins signature 1. 345 362 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CFK41_RS04625 40bab20479bc283b177c05365614b1a6 565 Pfam PF00083 Sugar (and other) transporter 51 477 2.1E-42 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CFK41_RS04625 40bab20479bc283b177c05365614b1a6 565 SUPERFAMILY SSF103473 46 470 2.49E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS04625 40bab20479bc283b177c05365614b1a6 565 Gene3D G3DSA:1.20.1250.20 32 273 9.9E-26 T 28-03-2018 CFK41_RS04625 40bab20479bc283b177c05365614b1a6 565 Gene3D G3DSA:1.20.1250.20 276 503 1.8E-21 T 28-03-2018 CFK41_RS04040 be3c3275692363b7085962cc7b449bc3 439 Gene3D G3DSA:3.90.1150.10 7 185 8.1E-36 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS04040 be3c3275692363b7085962cc7b449bc3 439 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 28 438 9.7E-136 T 28-03-2018 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855 CFK41_RS04040 be3c3275692363b7085962cc7b449bc3 439 SUPERFAMILY SSF53383 32 435 1.36E-102 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS04040 be3c3275692363b7085962cc7b449bc3 439 TIGRFAM TIGR02407 ectoine_ectB: diaminobutyrate--2-oxoglutarate aminotransferase 28 434 6.2E-190 T 28-03-2018 IPR012773 Ectoine biosynthetic protein GO:0019491|GO:0030170|GO:0047307 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855 CFK41_RS04040 be3c3275692363b7085962cc7b449bc3 439 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 254 290 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CFK41_RS04040 be3c3275692363b7085962cc7b449bc3 439 Pfam PF00202 Aminotransferase class-III 42 433 2.2E-72 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CFK41_RS04040 be3c3275692363b7085962cc7b449bc3 439 Gene3D G3DSA:3.40.640.10 200 324 1.1E-30 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS04040 be3c3275692363b7085962cc7b449bc3 439 Gene3D G3DSA:3.90.1150.10 325 438 3.7E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS04040 be3c3275692363b7085962cc7b449bc3 439 PIRSF PIRSF000521 2 149 1.2E-4 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CFK41_RS04040 be3c3275692363b7085962cc7b449bc3 439 PIRSF PIRSF000521 205 436 8.6E-31 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CFK41_RS04040 be3c3275692363b7085962cc7b449bc3 439 PIRSF PIRSF000521 142 182 0.11 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CFK41_RS17085 222f784eb9ff03ea79b6427a7b1e164e 412 SUPERFAMILY SSF103473 6 404 4.58E-53 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS17085 222f784eb9ff03ea79b6427a7b1e164e 412 Gene3D G3DSA:1.20.1250.20 197 407 2.0E-17 T 28-03-2018 CFK41_RS17085 222f784eb9ff03ea79b6427a7b1e164e 412 Gene3D G3DSA:1.20.1250.20 3 192 3.5E-26 T 28-03-2018 CFK41_RS17085 222f784eb9ff03ea79b6427a7b1e164e 412 Pfam PF07690 Major Facilitator Superfamily 13 356 3.9E-36 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS16725 935258f8b7c0e4c9b299fc684bcbd0f0 693 PRINTS PR00775 90kDa heat shock protein signature 97 117 1.2E-6 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CFK41_RS16725 935258f8b7c0e4c9b299fc684bcbd0f0 693 PRINTS PR00775 90kDa heat shock protein signature 118 140 1.2E-6 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CFK41_RS16725 935258f8b7c0e4c9b299fc684bcbd0f0 693 PRINTS PR00775 90kDa heat shock protein signature 250 267 1.2E-6 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CFK41_RS16725 935258f8b7c0e4c9b299fc684bcbd0f0 693 PRINTS PR00775 90kDa heat shock protein signature 268 286 1.2E-6 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CFK41_RS16725 935258f8b7c0e4c9b299fc684bcbd0f0 693 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 121 229 9.4E-10 T 28-03-2018 CFK41_RS16725 935258f8b7c0e4c9b299fc684bcbd0f0 693 SUPERFAMILY SSF54211 306 488 4.17E-20 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CFK41_RS16725 935258f8b7c0e4c9b299fc684bcbd0f0 693 SUPERFAMILY SSF55874 98 288 2.62E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS16725 935258f8b7c0e4c9b299fc684bcbd0f0 693 Gene3D G3DSA:3.30.565.10 94 300 1.1E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS11280 78741d416bd5fcd1742aa705a9e271cc 382 Gene3D G3DSA:3.30.300.130 9 93 5.2E-19 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CFK41_RS11280 78741d416bd5fcd1742aa705a9e271cc 382 Gene3D G3DSA:3.40.50.300 94 370 1.1E-51 T 28-03-2018 CFK41_RS11280 78741d416bd5fcd1742aa705a9e271cc 382 ProSitePatterns PS01215 Mrp family signature. 222 238 - T 28-03-2018 IPR000808 Mrp, conserved site GO:0005524 CFK41_RS11280 78741d416bd5fcd1742aa705a9e271cc 382 Pfam PF01883 Iron-sulfur cluster assembly protein 15 86 7.6E-15 T 28-03-2018 IPR002744 MIP18 family-like CFK41_RS11280 78741d416bd5fcd1742aa705a9e271cc 382 SUPERFAMILY SSF117916 14 104 2.13E-20 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CFK41_RS11280 78741d416bd5fcd1742aa705a9e271cc 382 SUPERFAMILY SSF52540 118 365 2.67E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11280 78741d416bd5fcd1742aa705a9e271cc 382 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 118 363 3.5E-83 T 28-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 CFK41_RS11280 78741d416bd5fcd1742aa705a9e271cc 382 Hamap MF_02040 Iron-sulfur cluster carrier protein. 100 364 32.361 T 28-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein CFK41_RS11720 f43a908512585740250512d463f7b317 341 Pfam PF06574 FAD synthetase 17 171 2.2E-38 T 28-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CFK41_RS11720 f43a908512585740250512d463f7b317 341 Gene3D G3DSA:3.40.50.620 4 185 9.4E-40 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS11720 f43a908512585740250512d463f7b317 341 SMART SM00904 189 331 8.5E-40 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CFK41_RS11720 f43a908512585740250512d463f7b317 341 Gene3D G3DSA:2.40.30.30 186 341 3.1E-39 T 28-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 CFK41_RS11720 f43a908512585740250512d463f7b317 341 SUPERFAMILY SSF82114 180 333 6.76E-34 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CFK41_RS11720 f43a908512585740250512d463f7b317 341 SUPERFAMILY SSF52374 20 181 5.96E-25 T 28-03-2018 CFK41_RS11720 f43a908512585740250512d463f7b317 341 Pfam PF01687 Riboflavin kinase 190 330 1.6E-29 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CFK41_RS11720 f43a908512585740250512d463f7b317 341 PIRSF PIRSF004491 4 337 9.1E-79 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CFK41_RS03900 72aff05ad1c320961674bac64328df57 550 SUPERFAMILY SSF53474 412 537 4.84E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS03900 72aff05ad1c320961674bac64328df57 550 SUPERFAMILY SSF53474 128 193 4.84E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS03900 72aff05ad1c320961674bac64328df57 550 SUPERFAMILY SSF53474 238 292 4.84E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS03900 72aff05ad1c320961674bac64328df57 550 Gene3D G3DSA:3.40.50.1820 84 540 3.7E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS03900 72aff05ad1c320961674bac64328df57 550 Pfam PF00561 alpha/beta hydrolase fold 143 523 2.3E-27 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CFK41_RS03255 5e5fb2fc079fbd916e818f788c2ce23a 814 Gene3D G3DSA:1.20.5.900 5 56 1.2E-4 T 28-03-2018 CFK41_RS14965 8cc7575f7ded2565d3f6f059ccc579ca 263 SMART SM00382 33 217 2.1E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS14965 8cc7575f7ded2565d3f6f059ccc579ca 263 SUPERFAMILY SSF52540 6 231 2.44E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS14965 8cc7575f7ded2565d3f6f059ccc579ca 263 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS14965 8cc7575f7ded2565d3f6f059ccc579ca 263 Gene3D G3DSA:3.40.50.300 5 248 1.1E-59 T 28-03-2018 CFK41_RS14965 8cc7575f7ded2565d3f6f059ccc579ca 263 Pfam PF00005 ABC transporter 24 173 1.7E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS15905 5ab365d0316f0b2a7221147eaf470971 480 PIRSF PIRSF036492 15 480 4.4E-162 T 28-03-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 CFK41_RS15905 5ab365d0316f0b2a7221147eaf470971 480 SUPERFAMILY SSF53720 28 465 1.09E-116 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CFK41_RS15905 5ab365d0316f0b2a7221147eaf470971 480 Gene3D G3DSA:3.40.309.10 249 430 2.6E-56 T 28-03-2018 CFK41_RS15905 5ab365d0316f0b2a7221147eaf470971 480 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 257 268 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CFK41_RS15905 5ab365d0316f0b2a7221147eaf470971 480 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 229 236 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CFK41_RS15905 5ab365d0316f0b2a7221147eaf470971 480 Gene3D G3DSA:3.40.605.10 3 248 2.0E-69 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CFK41_RS15905 5ab365d0316f0b2a7221147eaf470971 480 Pfam PF00171 Aldehyde dehydrogenase family 28 449 1.4E-81 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CFK41_RS09900 848e9b9f18d62099839b0949af8f338d 197 Pfam PF11241 Protein of unknown function (DUF3043) 24 194 1.0E-54 T 28-03-2018 IPR021403 Protein of unknown function DUF3043 CFK41_RS00895 93639ce2cada4beb7d4d112739e4db5d 266 ProSitePatterns PS00221 MIP family signature. 93 101 - T 28-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CFK41_RS00895 93639ce2cada4beb7d4d112739e4db5d 266 PRINTS PR00783 Major intrinsic protein family signature 29 48 2.5E-48 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CFK41_RS00895 93639ce2cada4beb7d4d112739e4db5d 266 PRINTS PR00783 Major intrinsic protein family signature 172 190 2.5E-48 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CFK41_RS00895 93639ce2cada4beb7d4d112739e4db5d 266 PRINTS PR00783 Major intrinsic protein family signature 112 131 2.5E-48 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CFK41_RS00895 93639ce2cada4beb7d4d112739e4db5d 266 PRINTS PR00783 Major intrinsic protein family signature 75 99 2.5E-48 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CFK41_RS00895 93639ce2cada4beb7d4d112739e4db5d 266 PRINTS PR00783 Major intrinsic protein family signature 202 224 2.5E-48 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CFK41_RS00895 93639ce2cada4beb7d4d112739e4db5d 266 PRINTS PR00783 Major intrinsic protein family signature 241 261 2.5E-48 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CFK41_RS00895 93639ce2cada4beb7d4d112739e4db5d 266 Pfam PF00230 Major intrinsic protein 24 258 4.4E-46 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CFK41_RS00895 93639ce2cada4beb7d4d112739e4db5d 266 Gene3D G3DSA:1.20.1080.10 2 266 1.5E-60 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CFK41_RS00895 93639ce2cada4beb7d4d112739e4db5d 266 SUPERFAMILY SSF81338 25 263 2.62E-53 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CFK41_RS10830 47be753abb988ccff3986cac4b7e0f1a 161 Gene3D G3DSA:3.90.280.10 1 160 4.9E-40 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CFK41_RS10830 47be753abb988ccff3986cac4b7e0f1a 161 SUPERFAMILY SSF49777 28 157 5.49E-41 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CFK41_RS10830 47be753abb988ccff3986cac4b7e0f1a 161 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 22 153 5.7E-36 T 28-03-2018 IPR005247 YbhB/YbcL CFK41_RS10830 47be753abb988ccff3986cac4b7e0f1a 161 Pfam PF01161 Phosphatidylethanolamine-binding protein 30 157 7.3E-34 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CFK41_RS02730 37e5bfee555177b7b6874d7ee1daa5ee 322 Gene3D G3DSA:1.10.3720.10 90 316 8.7E-37 T 28-03-2018 CFK41_RS02730 37e5bfee555177b7b6874d7ee1daa5ee 322 SUPERFAMILY SSF161098 29 322 1.13E-55 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS02730 37e5bfee555177b7b6874d7ee1daa5ee 322 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 315 3.6E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS14770 8fb212ff2a9597ca9d5563112606e31b 290 SMART SM00342 203 286 8.0E-25 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CFK41_RS14770 8fb212ff2a9597ca9d5563112606e31b 290 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 240 282 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CFK41_RS14770 8fb212ff2a9597ca9d5563112606e31b 290 Gene3D G3DSA:2.60.120.280 18 161 3.2E-12 T 28-03-2018 CFK41_RS14770 8fb212ff2a9597ca9d5563112606e31b 290 Gene3D G3DSA:1.10.10.60 180 242 1.6E-9 T 28-03-2018 CFK41_RS14770 8fb212ff2a9597ca9d5563112606e31b 290 Gene3D G3DSA:1.10.10.60 243 290 2.0E-13 T 28-03-2018 CFK41_RS14770 8fb212ff2a9597ca9d5563112606e31b 290 SUPERFAMILY SSF46689 240 288 5.38E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS14770 8fb212ff2a9597ca9d5563112606e31b 290 SUPERFAMILY SSF46689 188 236 1.7E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS14770 8fb212ff2a9597ca9d5563112606e31b 290 Pfam PF12833 Helix-turn-helix domain 209 288 1.4E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CFK41_RS14770 8fb212ff2a9597ca9d5563112606e31b 290 Pfam PF07883 Cupin domain 28 86 5.6E-8 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CFK41_RS14770 8fb212ff2a9597ca9d5563112606e31b 290 SUPERFAMILY SSF51182 12 86 2.89E-9 T 28-03-2018 IPR011051 RmlC-like cupin domain CFK41_RS06225 1c880db3a7c7928e40711b227383cfd3 274 Gene3D G3DSA:3.90.550.10 4 240 2.1E-20 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS06225 1c880db3a7c7928e40711b227383cfd3 274 SUPERFAMILY SSF53448 10 226 9.85E-26 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS06225 1c880db3a7c7928e40711b227383cfd3 274 Pfam PF00535 Glycosyl transferase family 2 23 163 1.7E-13 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CFK41_RS10290 8f5c27adfa1b9a87ff6c52ab581f0331 707 Pfam PF02446 4-alpha-glucanotransferase 179 674 1.4E-105 T 28-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CFK41_RS10290 8f5c27adfa1b9a87ff6c52ab581f0331 707 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 131 677 2.0E-90 T 28-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CFK41_RS10290 8f5c27adfa1b9a87ff6c52ab581f0331 707 Gene3D G3DSA:3.20.20.80 168 693 7.1E-153 T 28-03-2018 CFK41_RS10290 8f5c27adfa1b9a87ff6c52ab581f0331 707 SUPERFAMILY SSF51445 171 591 1.61E-125 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS10290 8f5c27adfa1b9a87ff6c52ab581f0331 707 SUPERFAMILY SSF51445 619 695 1.61E-125 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS15525 af1219a6b10ad057377513d1c5dbd199 286 Pfam PF00582 Universal stress protein family 152 281 4.0E-18 T 28-03-2018 IPR006016 UspA GO:0006950 CFK41_RS15525 af1219a6b10ad057377513d1c5dbd199 286 Pfam PF00582 Universal stress protein family 7 143 7.0E-22 T 28-03-2018 IPR006016 UspA GO:0006950 CFK41_RS15525 af1219a6b10ad057377513d1c5dbd199 286 PRINTS PR01438 Universal stress protein signature 121 143 3.9E-11 T 28-03-2018 IPR006015 Universal stress protein A CFK41_RS15525 af1219a6b10ad057377513d1c5dbd199 286 PRINTS PR01438 Universal stress protein signature 5 23 3.9E-11 T 28-03-2018 IPR006015 Universal stress protein A CFK41_RS15525 af1219a6b10ad057377513d1c5dbd199 286 PRINTS PR01438 Universal stress protein signature 103 115 3.9E-11 T 28-03-2018 IPR006015 Universal stress protein A CFK41_RS15525 af1219a6b10ad057377513d1c5dbd199 286 Gene3D G3DSA:3.40.50.620 3 146 1.0E-31 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS15525 af1219a6b10ad057377513d1c5dbd199 286 Gene3D G3DSA:3.40.50.620 147 286 3.1E-23 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS15525 af1219a6b10ad057377513d1c5dbd199 286 SUPERFAMILY SSF52402 151 283 2.09E-20 T 28-03-2018 CFK41_RS15525 af1219a6b10ad057377513d1c5dbd199 286 SUPERFAMILY SSF52402 7 146 1.51E-29 T 28-03-2018 CFK41_RS01260 ba33164bf51ed926eb7f4332d4b6d65a 331 Pfam PF02146 Sir2 family 79 284 2.1E-34 T 28-03-2018 IPR003000 Sirtuin family GO:0070403 CFK41_RS01260 ba33164bf51ed926eb7f4332d4b6d65a 331 Gene3D G3DSA:3.40.50.1220 56 330 5.5E-54 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CFK41_RS01260 ba33164bf51ed926eb7f4332d4b6d65a 331 SUPERFAMILY SSF52467 62 191 1.4E-65 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CFK41_RS01260 ba33164bf51ed926eb7f4332d4b6d65a 331 SUPERFAMILY SSF52467 221 329 1.4E-65 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CFK41_RS15550 fa02469abd1c2df4e9aeeff6a6214cb8 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 159 1.3E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS15550 fa02469abd1c2df4e9aeeff6a6214cb8 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 98 109 1.3E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS15550 fa02469abd1c2df4e9aeeff6a6214cb8 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 190 1.3E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS15550 fa02469abd1c2df4e9aeeff6a6214cb8 267 SUPERFAMILY SSF51735 18 266 2.42E-73 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS15550 fa02469abd1c2df4e9aeeff6a6214cb8 267 Gene3D G3DSA:3.40.50.720 12 54 5.0E-11 T 28-03-2018 CFK41_RS15550 fa02469abd1c2df4e9aeeff6a6214cb8 267 Gene3D G3DSA:3.40.50.720 55 267 1.2E-57 T 28-03-2018 CFK41_RS15550 fa02469abd1c2df4e9aeeff6a6214cb8 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 98 109 7.9E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS15550 fa02469abd1c2df4e9aeeff6a6214cb8 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 7.9E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS15550 fa02469abd1c2df4e9aeeff6a6214cb8 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 7.9E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS15550 fa02469abd1c2df4e9aeeff6a6214cb8 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 7.9E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS15550 fa02469abd1c2df4e9aeeff6a6214cb8 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 20 37 7.9E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS15550 fa02469abd1c2df4e9aeeff6a6214cb8 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 228 248 7.9E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS15550 fa02469abd1c2df4e9aeeff6a6214cb8 267 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 19 193 0.0017 T 28-03-2018 CFK41_RS15550 fa02469abd1c2df4e9aeeff6a6214cb8 267 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 25 264 2.4E-58 T 28-03-2018 CFK41_RS08925 a4122eabd18f16fb8ce8226712142aa3 254 Gene3D G3DSA:1.20.120.450 62 247 1.9E-18 T 28-03-2018 CFK41_RS08925 a4122eabd18f16fb8ce8226712142aa3 254 Pfam PF12867 DinB superfamily 101 245 4.9E-15 T 28-03-2018 IPR024775 DinB-like domain CFK41_RS08925 a4122eabd18f16fb8ce8226712142aa3 254 SUPERFAMILY SSF109854 89 244 6.11E-11 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CFK41_RS04320 1fb05c81e8e1b25808d07b6b13e6130f 101 SUPERFAMILY SSF52833 14 90 8.77E-15 T 28-03-2018 IPR012336 Thioredoxin-like fold CFK41_RS04320 1fb05c81e8e1b25808d07b6b13e6130f 101 Pfam PF05768 Glutaredoxin-like domain (DUF836) 18 88 1.1E-12 T 28-03-2018 IPR008554 Glutaredoxin-like CFK41_RS04320 1fb05c81e8e1b25808d07b6b13e6130f 101 Gene3D G3DSA:3.40.30.10 14 90 8.4E-10 T 28-03-2018 CFK41_RS05435 542f5c728d82e7d94d34d49c880dd1f8 306 Pfam PF01636 Phosphotransferase enzyme family 38 267 1.2E-20 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CFK41_RS05435 542f5c728d82e7d94d34d49c880dd1f8 306 SUPERFAMILY SSF56112 39 254 1.87E-28 T 28-03-2018 IPR011009 Protein kinase-like domain CFK41_RS05435 542f5c728d82e7d94d34d49c880dd1f8 306 Gene3D G3DSA:3.90.1200.10 119 299 8.8E-16 T 28-03-2018 CFK41_RS10775 f8e74eeea37e013d0ee6c7fea355518a 195 Gene3D G3DSA:1.10.3130.10 1 68 1.3E-23 T 28-03-2018 CFK41_RS10775 f8e74eeea37e013d0ee6c7fea355518a 195 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 16 176 4.7E-71 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CFK41_RS10775 f8e74eeea37e013d0ee6c7fea355518a 195 Gene3D G3DSA:2.160.10.10 69 192 2.9E-35 T 28-03-2018 CFK41_RS10775 f8e74eeea37e013d0ee6c7fea355518a 195 PIRSF PIRSF000441 10 192 1.0E-75 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CFK41_RS10775 f8e74eeea37e013d0ee6c7fea355518a 195 SUPERFAMILY SSF51161 13 180 3.19E-55 T 28-03-2018 IPR011004 Trimeric LpxA-like CFK41_RS10775 f8e74eeea37e013d0ee6c7fea355518a 195 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 128 161 4.7E-8 T 28-03-2018 IPR001451 Hexapeptide repeat CFK41_RS10775 f8e74eeea37e013d0ee6c7fea355518a 195 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 83 119 4.6E-4 T 28-03-2018 IPR001451 Hexapeptide repeat CFK41_RS10775 f8e74eeea37e013d0ee6c7fea355518a 195 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 137 165 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CFK41_RS17115 32e871c167b3dc41b3733dd970eefff9 328 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 192 287 2.3E-19 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CFK41_RS17115 32e871c167b3dc41b3733dd970eefff9 328 SUPERFAMILY SSF48179 191 286 2.89E-20 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CFK41_RS17115 32e871c167b3dc41b3733dd970eefff9 328 Gene3D G3DSA:1.10.1040.10 192 287 4.0E-23 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CFK41_RS17115 32e871c167b3dc41b3733dd970eefff9 328 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 10 189 8.0E-51 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CFK41_RS17115 32e871c167b3dc41b3733dd970eefff9 328 Gene3D G3DSA:3.40.50.720 2 191 3.6E-43 T 28-03-2018 CFK41_RS17115 32e871c167b3dc41b3733dd970eefff9 328 PIRSF PIRSF000105 4 320 3.3E-77 T 28-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CFK41_RS17115 32e871c167b3dc41b3733dd970eefff9 328 SUPERFAMILY SSF51735 7 191 5.5E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS04835 65d7bda6f14ff1b5d2ec1f55858cc245 241 SUPERFAMILY SSF52317 1 237 3.01E-67 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS04835 65d7bda6f14ff1b5d2ec1f55858cc245 241 PIRSF PIRSF001586 1 241 3.4E-82 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CFK41_RS04835 65d7bda6f14ff1b5d2ec1f55858cc245 241 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 237 39.721 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CFK41_RS04835 65d7bda6f14ff1b5d2ec1f55858cc245 241 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 236 1.7E-81 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CFK41_RS04835 65d7bda6f14ff1b5d2ec1f55858cc245 241 Gene3D G3DSA:3.40.50.880 1 240 3.9E-35 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS04835 65d7bda6f14ff1b5d2ec1f55858cc245 241 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 234 9.5E-39 T 28-03-2018 CFK41_RS04835 65d7bda6f14ff1b5d2ec1f55858cc245 241 SMART SM01211 1 239 6.8E-119 T 28-03-2018 CFK41_RS02010 fb07736d66b4225ac75de0da74425258 296 SUPERFAMILY SSF47413 30 79 6.33E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS02010 fb07736d66b4225ac75de0da74425258 296 Gene3D G3DSA:1.10.260.40 2 94 1.9E-11 T 28-03-2018 CFK41_RS02010 fb07736d66b4225ac75de0da74425258 296 SMART SM00530 6 82 2.3E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CFK41_RS02010 fb07736d66b4225ac75de0da74425258 296 Pfam PF13560 Helix-turn-helix domain 11 85 1.5E-12 T 28-03-2018 CFK41_RS10170 5590f7a2ff52fce32c34bd006ee103f7 263 Gene3D G3DSA:3.40.50.1360 1 261 5.7E-76 T 28-03-2018 CFK41_RS10170 5590f7a2ff52fce32c34bd006ee103f7 263 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 9 228 3.8E-22 T 28-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 CFK41_RS10170 5590f7a2ff52fce32c34bd006ee103f7 263 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 122 140 - T 28-03-2018 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 CFK41_RS10170 5590f7a2ff52fce32c34bd006ee103f7 263 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 243 39.36 T 28-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 CFK41_RS10170 5590f7a2ff52fce32c34bd006ee103f7 263 SUPERFAMILY SSF100950 1 253 1.63E-87 T 28-03-2018 CFK41_RS10170 5590f7a2ff52fce32c34bd006ee103f7 263 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 3 247 3.5E-76 T 28-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 CFK41_RS12050 4c77a050204c55c4f73d23e5e285ccc6 261 Pfam PF06182 ABC-2 family transporter protein 29 260 1.1E-43 T 28-03-2018 IPR010390 Protein of unknown function DUF990 CFK41_RS10845 90cefc4bf9898b43474ce479216df20b 377 Gene3D G3DSA:3.40.50.2000 175 347 4.8E-27 T 28-03-2018 CFK41_RS10845 90cefc4bf9898b43474ce479216df20b 377 Gene3D G3DSA:3.40.50.2000 4 174 1.2E-12 T 28-03-2018 CFK41_RS10845 90cefc4bf9898b43474ce479216df20b 377 Pfam PF13439 Glycosyltransferase Family 4 68 166 3.5E-16 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CFK41_RS10845 90cefc4bf9898b43474ce479216df20b 377 Pfam PF00534 Glycosyl transferases group 1 175 333 1.0E-12 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CFK41_RS10845 90cefc4bf9898b43474ce479216df20b 377 SUPERFAMILY SSF53756 40 360 1.62E-50 T 28-03-2018 CFK41_RS00455 ba36bd88405a775bec73e7be2af95f95 318 Pfam PF02517 CAAX protease self-immunity 151 254 5.5E-11 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CFK41_RS08005 5ae53c49098937eb82496693e7e7e37e 421 Pfam PF03663 Glycosyl hydrolase family 76 210 347 1.0E-19 T 28-03-2018 IPR005198 Glycoside hydrolase, family 76 KEGG: 00052+3.2.1.10|KEGG: 00500+3.2.1.10 CFK41_RS08005 5ae53c49098937eb82496693e7e7e37e 421 Gene3D G3DSA:1.50.10.20 48 410 3.6E-24 T 28-03-2018 CFK41_RS08005 5ae53c49098937eb82496693e7e7e37e 421 SUPERFAMILY SSF48208 160 393 1.36E-16 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CFK41_RS03300 37a27eae513b14aa626cdb35171d1d2a 671 Gene3D G3DSA:3.90.550.10 1 274 9.7E-46 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS03300 37a27eae513b14aa626cdb35171d1d2a 671 SUPERFAMILY SSF53448 3 212 1.78E-48 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS03300 37a27eae513b14aa626cdb35171d1d2a 671 Pfam PF00535 Glycosyl transferase family 2 6 167 1.1E-31 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CFK41_RS06270 d045b78190905a747d30a35826fdfc43 543 Gene3D G3DSA:2.60.290.11 180 297 2.2E-15 T 28-03-2018 CFK41_RS06270 d045b78190905a747d30a35826fdfc43 543 Gene3D G3DSA:2.60.290.11 415 530 5.2E-4 T 28-03-2018 CFK41_RS06270 d045b78190905a747d30a35826fdfc43 543 Gene3D G3DSA:2.60.290.11 298 413 2.2E-16 T 28-03-2018 CFK41_RS10525 5657ca40d072982b53058cf728aa71a6 170 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 52 58 - T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CFK41_RS10525 5657ca40d072982b53058cf728aa71a6 170 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 1 158 30.886 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CFK41_RS10525 5657ca40d072982b53058cf728aa71a6 170 Pfam PF00719 Inorganic pyrophosphatase 5 156 1.4E-49 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CFK41_RS10525 5657ca40d072982b53058cf728aa71a6 170 Gene3D G3DSA:3.90.80.10 1 163 3.8E-48 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CFK41_RS10525 5657ca40d072982b53058cf728aa71a6 170 SUPERFAMILY SSF50324 3 156 3.79E-53 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CFK41_RS03925 74e44f03011a26a2f0cfef4f18b051ee 497 SMART SM01060 11 393 8.3E-267 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CFK41_RS03925 74e44f03011a26a2f0cfef4f18b051ee 497 PIRSF PIRSF038928 2 487 3.8E-228 T 28-03-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CFK41_RS03925 74e44f03011a26a2f0cfef4f18b051ee 497 Pfam PF00199 Catalase 11 389 7.2E-181 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CFK41_RS03925 74e44f03011a26a2f0cfef4f18b051ee 497 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 336 344 - T 28-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CFK41_RS03925 74e44f03011a26a2f0cfef4f18b051ee 497 Gene3D G3DSA:2.40.180.10 4 360 1.9E-154 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CFK41_RS03925 74e44f03011a26a2f0cfef4f18b051ee 497 ProSitePatterns PS00438 Catalase proximal active site signature. 47 63 - T 28-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CFK41_RS03925 74e44f03011a26a2f0cfef4f18b051ee 497 PRINTS PR00067 Catalase signature 107 124 2.1E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CFK41_RS03925 74e44f03011a26a2f0cfef4f18b051ee 497 PRINTS PR00067 Catalase signature 24 47 2.1E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CFK41_RS03925 74e44f03011a26a2f0cfef4f18b051ee 497 PRINTS PR00067 Catalase signature 86 104 2.1E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CFK41_RS03925 74e44f03011a26a2f0cfef4f18b051ee 497 PRINTS PR00067 Catalase signature 126 144 2.1E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CFK41_RS03925 74e44f03011a26a2f0cfef4f18b051ee 497 PRINTS PR00067 Catalase signature 291 318 2.1E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CFK41_RS03925 74e44f03011a26a2f0cfef4f18b051ee 497 PRINTS PR00067 Catalase signature 323 349 2.1E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CFK41_RS03925 74e44f03011a26a2f0cfef4f18b051ee 497 SUPERFAMILY SSF56634 7 483 1.96E-195 T 28-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CFK41_RS03925 74e44f03011a26a2f0cfef4f18b051ee 497 Pfam PF06628 Catalase-related immune-responsive 421 481 1.0E-12 T 28-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CFK41_RS05810 83cef0d23f017abfc48482ff8e0a486c 194 Gene3D G3DSA:3.30.1360.40 94 165 3.3E-27 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CFK41_RS05810 83cef0d23f017abfc48482ff8e0a486c 194 SUPERFAMILY SSF46785 10 78 3.13E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS05810 83cef0d23f017abfc48482ff8e0a486c 194 Gene3D G3DSA:1.10.10.10 12 75 5.5E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS05810 83cef0d23f017abfc48482ff8e0a486c 194 PRINTS PR01467 Bacterial arginine repressor signature 108 121 7.3E-24 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CFK41_RS05810 83cef0d23f017abfc48482ff8e0a486c 194 PRINTS PR01467 Bacterial arginine repressor signature 46 61 7.3E-24 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CFK41_RS05810 83cef0d23f017abfc48482ff8e0a486c 194 PRINTS PR01467 Bacterial arginine repressor signature 138 153 7.3E-24 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CFK41_RS05810 83cef0d23f017abfc48482ff8e0a486c 194 PRINTS PR01467 Bacterial arginine repressor signature 30 43 7.3E-24 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CFK41_RS05810 83cef0d23f017abfc48482ff8e0a486c 194 Pfam PF01316 Arginine repressor, DNA binding domain 11 78 3.7E-22 T 28-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 CFK41_RS05810 83cef0d23f017abfc48482ff8e0a486c 194 TIGRFAM TIGR01529 argR_whole: arginine repressor 14 168 4.2E-40 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CFK41_RS05810 83cef0d23f017abfc48482ff8e0a486c 194 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 110 155 5.0E-13 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CFK41_RS05810 83cef0d23f017abfc48482ff8e0a486c 194 Pfam PF02863 Arginine repressor, C-terminal domain 103 165 1.0E-22 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CFK41_RS05810 83cef0d23f017abfc48482ff8e0a486c 194 Hamap MF_00173 Arginine repressor [argR]. 1 172 55.453 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CFK41_RS05810 83cef0d23f017abfc48482ff8e0a486c 194 SUPERFAMILY SSF55252 101 167 1.44E-17 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CFK41_RS16730 e45bfcdc192684bd3f51f8176d114ae5 135 ProSitePatterns PS00893 Nudix box signature. 32 53 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CFK41_RS16730 e45bfcdc192684bd3f51f8176d114ae5 135 Gene3D G3DSA:3.90.79.10 1 130 7.8E-26 T 28-03-2018 CFK41_RS16730 e45bfcdc192684bd3f51f8176d114ae5 135 SUPERFAMILY SSF55811 1 121 3.11E-27 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CFK41_RS16730 e45bfcdc192684bd3f51f8176d114ae5 135 Pfam PF00293 NUDIX domain 2 118 6.0E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CFK41_RS16730 e45bfcdc192684bd3f51f8176d114ae5 135 PRINTS PR00502 NUDIX hydrolase family signature 41 56 6.4E-8 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CFK41_RS16730 e45bfcdc192684bd3f51f8176d114ae5 135 PRINTS PR00502 NUDIX hydrolase family signature 27 41 6.4E-8 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CFK41_RS02060 b17bfaaaae83550afaeb6bfa745e4225 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 144 199 4.9E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS02060 b17bfaaaae83550afaeb6bfa745e4225 210 SMART SM00421 142 199 2.7E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS02060 b17bfaaaae83550afaeb6bfa745e4225 210 SMART SM00448 1 112 2.3E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS02060 b17bfaaaae83550afaeb6bfa745e4225 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 159 186 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS02060 b17bfaaaae83550afaeb6bfa745e4225 210 Pfam PF00072 Response regulator receiver domain 2 113 1.1E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS02060 b17bfaaaae83550afaeb6bfa745e4225 210 Gene3D G3DSA:1.10.10.10 124 209 2.0E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS02060 b17bfaaaae83550afaeb6bfa745e4225 210 SUPERFAMILY SSF46894 133 207 1.02E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CFK41_RS02060 b17bfaaaae83550afaeb6bfa745e4225 210 Gene3D G3DSA:3.40.50.2300 1 123 3.9E-29 T 28-03-2018 CFK41_RS02060 b17bfaaaae83550afaeb6bfa745e4225 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 145 159 1.1E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS02060 b17bfaaaae83550afaeb6bfa745e4225 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 175 1.1E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS02060 b17bfaaaae83550afaeb6bfa745e4225 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 187 1.1E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS02060 b17bfaaaae83550afaeb6bfa745e4225 210 SUPERFAMILY SSF52172 2 122 1.71E-29 T 28-03-2018 IPR011006 CheY-like superfamily CFK41_RS08910 90a3d879cff4d5cd83d0e0ba6d0d405c 266 SMART SM00641 54 163 8.8E-31 T 28-03-2018 IPR018077 Glycoside hydrolase, family 25 subgroup CFK41_RS08910 90a3d879cff4d5cd83d0e0ba6d0d405c 266 SUPERFAMILY SSF51445 51 257 7.37E-53 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS08910 90a3d879cff4d5cd83d0e0ba6d0d405c 266 Pfam PF01183 Glycosyl hydrolases family 25 58 240 8.1E-42 T 28-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 CFK41_RS08910 90a3d879cff4d5cd83d0e0ba6d0d405c 266 Gene3D G3DSA:3.20.20.80 39 263 8.0E-57 T 28-03-2018 CFK41_RS03745 cef4701c0eb92669d87ea9c8343f85fe 323 Gene3D G3DSA:3.40.50.10490 19 254 2.1E-42 T 28-03-2018 CFK41_RS03745 cef4701c0eb92669d87ea9c8343f85fe 323 Pfam PF13580 SIS domain 52 174 1.2E-9 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CFK41_RS03745 cef4701c0eb92669d87ea9c8343f85fe 323 Gene3D G3DSA:1.10.8.10 255 284 4.8E-4 T 28-03-2018 CFK41_RS03745 cef4701c0eb92669d87ea9c8343f85fe 323 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 16 308 33.509 T 28-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 CFK41_RS03745 cef4701c0eb92669d87ea9c8343f85fe 323 SUPERFAMILY SSF53697 22 260 7.79E-62 T 28-03-2018 CFK41_RS03745 cef4701c0eb92669d87ea9c8343f85fe 323 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 198 215 - T 28-03-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 CFK41_RS13810 cc9604307ab78b38b1e0a997355adb30 193 Pfam PF00857 Isochorismatase family 4 190 3.1E-21 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CFK41_RS13810 cc9604307ab78b38b1e0a997355adb30 193 SUPERFAMILY SSF52499 2 190 5.23E-31 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CFK41_RS13810 cc9604307ab78b38b1e0a997355adb30 193 Gene3D G3DSA:3.40.50.850 1 193 6.3E-44 T 28-03-2018 CFK41_RS11795 22056a618e4ab4d10efdd3b764f6d095 386 SUPERFAMILY SSF56014 277 362 4.25E-12 T 28-03-2018 CFK41_RS11795 22056a618e4ab4d10efdd3b764f6d095 386 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 19 369 33.071 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CFK41_RS11795 22056a618e4ab4d10efdd3b764f6d095 386 SUPERFAMILY SSF51717 50 220 1.33E-8 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CFK41_RS11795 22056a618e4ab4d10efdd3b764f6d095 386 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 21 361 1.0E-124 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CFK41_RS11795 22056a618e4ab4d10efdd3b764f6d095 386 Pfam PF04551 GcpE protein 24 363 2.4E-129 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CFK41_RS11795 22056a618e4ab4d10efdd3b764f6d095 386 PIRSF PIRSF004640 15 375 4.0E-138 T 28-03-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CFK41_RS11795 22056a618e4ab4d10efdd3b764f6d095 386 Gene3D G3DSA:3.20.20.120 32 218 1.8E-18 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS02350 a8d717167e4cbd730e14c508b328f432 543 SUPERFAMILY SSF103088 242 355 1.7E-27 T 28-03-2018 IPR006665 OmpA-like domain CFK41_RS02350 a8d717167e4cbd730e14c508b328f432 543 Pfam PF00691 OmpA family 253 349 3.5E-14 T 28-03-2018 IPR006665 OmpA-like domain CFK41_RS02350 a8d717167e4cbd730e14c508b328f432 543 PRINTS PR01021 OMPA domain signature 254 276 1.9E-11 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CFK41_RS02350 a8d717167e4cbd730e14c508b328f432 543 PRINTS PR01021 OMPA domain signature 299 315 1.9E-11 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CFK41_RS02350 a8d717167e4cbd730e14c508b328f432 543 PRINTS PR01021 OMPA domain signature 284 299 1.9E-11 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CFK41_RS02350 a8d717167e4cbd730e14c508b328f432 543 Gene3D G3DSA:3.30.1330.60 220 368 3.8E-32 T 28-03-2018 IPR006665 OmpA-like domain CFK41_RS08735 be405f30540f616ce850471f0a314c51 277 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 1 239 14.284 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CFK41_RS08735 be405f30540f616ce850471f0a314c51 277 Pfam PF00902 Sec-independent protein translocase protein (TatC) 5 217 7.7E-46 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CFK41_RS08735 be405f30540f616ce850471f0a314c51 277 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 4 225 2.7E-44 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CFK41_RS08735 be405f30540f616ce850471f0a314c51 277 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 100 126 2.5E-31 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CFK41_RS08735 be405f30540f616ce850471f0a314c51 277 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 152 180 2.5E-31 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CFK41_RS08735 be405f30540f616ce850471f0a314c51 277 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 82 100 2.5E-31 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CFK41_RS08735 be405f30540f616ce850471f0a314c51 277 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 2 29 2.5E-31 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CFK41_RS15360 1e898523c028d9e3730f6c1671528aac 544 SUPERFAMILY SSF51905 4 259 3.76E-64 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS15360 1e898523c028d9e3730f6c1671528aac 544 SUPERFAMILY SSF51905 351 408 3.76E-64 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS15360 1e898523c028d9e3730f6c1671528aac 544 Pfam PF02910 Fumarate reductase flavoprotein C-term 440 517 1.8E-5 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CFK41_RS15360 1e898523c028d9e3730f6c1671528aac 544 SUPERFAMILY SSF56425 232 348 2.09E-37 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CFK41_RS15360 1e898523c028d9e3730f6c1671528aac 544 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 350 372 4.7E-10 T 28-03-2018 CFK41_RS15360 1e898523c028d9e3730f6c1671528aac 544 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 4.7E-10 T 28-03-2018 CFK41_RS15360 1e898523c028d9e3730f6c1671528aac 544 Pfam PF00890 FAD binding domain 10 387 7.8E-94 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CFK41_RS15360 1e898523c028d9e3730f6c1671528aac 544 Gene3D G3DSA:3.50.50.60 3 297 1.5E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS15360 1e898523c028d9e3730f6c1671528aac 544 Gene3D G3DSA:3.50.50.60 298 403 7.1E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS15360 1e898523c028d9e3730f6c1671528aac 544 Gene3D G3DSA:1.20.58.100 429 519 1.9E-16 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CFK41_RS15360 1e898523c028d9e3730f6c1671528aac 544 SUPERFAMILY SSF46977 438 520 7.46E-18 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CFK41_RS15360 1e898523c028d9e3730f6c1671528aac 544 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 9 516 7.9E-153 T 28-03-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 CFK41_RS17505 8ad166054e4913f7c48a264cdde740a7 224 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 12 209 24.116 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CFK41_RS17505 8ad166054e4913f7c48a264cdde740a7 224 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 24 189 2.4E-39 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CFK41_RS17505 8ad166054e4913f7c48a264cdde740a7 224 Pfam PF02527 rRNA small subunit methyltransferase G 20 193 9.6E-48 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CFK41_RS17505 8ad166054e4913f7c48a264cdde740a7 224 SUPERFAMILY SSF53335 19 211 1.17E-29 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS17505 8ad166054e4913f7c48a264cdde740a7 224 Gene3D G3DSA:3.40.50.150 6 223 1.6E-27 T 28-03-2018 CFK41_RS17505 8ad166054e4913f7c48a264cdde740a7 224 PIRSF PIRSF003078 4 215 2.7E-45 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CFK41_RS10515 6852652e91e9211178df9b31b3a4c83e 364 Gene3D G3DSA:3.40.50.620 35 267 5.7E-34 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS10515 6852652e91e9211178df9b31b3a4c83e 364 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 23 330 20.015 T 28-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CFK41_RS10515 6852652e91e9211178df9b31b3a4c83e 364 Pfam PF01171 PP-loop family 39 222 8.0E-36 T 28-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CFK41_RS10515 6852652e91e9211178df9b31b3a4c83e 364 SUPERFAMILY SSF82829 235 356 7.85E-9 T 28-03-2018 CFK41_RS10515 6852652e91e9211178df9b31b3a4c83e 364 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 38 226 1.5E-38 T 28-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CFK41_RS10515 6852652e91e9211178df9b31b3a4c83e 364 SUPERFAMILY SSF52402 37 255 7.18E-43 T 28-03-2018 CFK41_RS00125 83c66b872e9bf7d8666bb1147176c5e7 130 SUPERFAMILY SSF54909 1 123 1.5E-17 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CFK41_RS00125 83c66b872e9bf7d8666bb1147176c5e7 130 Gene3D G3DSA:3.30.70.1060 1 127 7.5E-30 T 28-03-2018 CFK41_RS00125 83c66b872e9bf7d8666bb1147176c5e7 130 Pfam PF03795 YCII-related domain 1 108 3.0E-7 T 28-03-2018 IPR005545 YCII-related CFK41_RS09065 0ebbb67fc1e98a38362a5a65ac1e1e2a 119 Gene3D G3DSA:3.90.550.10 21 119 2.9E-4 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS07710 b426e21fc33c0fa50a80f3c849247e98 473 SUPERFAMILY SSF49899 376 468 2.69E-5 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CFK41_RS07710 b426e21fc33c0fa50a80f3c849247e98 473 Gene3D G3DSA:2.115.10.20 2 324 1.4E-87 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CFK41_RS07710 b426e21fc33c0fa50a80f3c849247e98 473 SUPERFAMILY SSF75005 10 325 2.48E-90 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CFK41_RS07710 b426e21fc33c0fa50a80f3c849247e98 473 Gene3D G3DSA:2.60.120.560 325 470 2.5E-8 T 28-03-2018 CFK41_RS07710 b426e21fc33c0fa50a80f3c849247e98 473 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 401 464 2.0E-5 T 28-03-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal CFK41_RS07710 b426e21fc33c0fa50a80f3c849247e98 473 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 19 32 - T 28-03-2018 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 CFK41_RS07710 b426e21fc33c0fa50a80f3c849247e98 473 SMART SM00640 19 450 5.3E-106 T 28-03-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 CFK41_RS07710 b426e21fc33c0fa50a80f3c849247e98 473 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 19 325 6.2E-82 T 28-03-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal CFK41_RS06040 8b749a0f06914b94c59a0561b428ebe5 143 Gene3D G3DSA:3.40.140.10 2 142 4.2E-39 T 28-03-2018 CFK41_RS06040 8b749a0f06914b94c59a0561b428ebe5 143 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 13 120 6.1E-13 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CFK41_RS06040 8b749a0f06914b94c59a0561b428ebe5 143 SUPERFAMILY SSF53927 7 141 1.19E-37 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CFK41_RS05470 e4d4c8a2066d56e5191b50fbb396dc22 198 PIRSF PIRSF035805 4 196 4.5E-49 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CFK41_RS05470 e4d4c8a2066d56e5191b50fbb396dc22 198 Pfam PF00265 Thymidine kinase 7 190 1.1E-41 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CFK41_RS05470 e4d4c8a2066d56e5191b50fbb396dc22 198 Gene3D G3DSA:3.40.50.300 6 145 9.2E-34 T 28-03-2018 CFK41_RS05470 e4d4c8a2066d56e5191b50fbb396dc22 198 Gene3D G3DSA:3.30.60.20 146 196 8.3E-14 T 28-03-2018 CFK41_RS05470 e4d4c8a2066d56e5191b50fbb396dc22 198 SUPERFAMILY SSF57716 146 190 4.75E-10 T 28-03-2018 CFK41_RS05470 e4d4c8a2066d56e5191b50fbb396dc22 198 Hamap MF_00124 Thymidine kinase [tdk]. 6 194 29.234 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CFK41_RS05470 e4d4c8a2066d56e5191b50fbb396dc22 198 SUPERFAMILY SSF52540 7 146 3.19E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS12035 f527d90725f006ed1d8e3023be2a2481 154 SUPERFAMILY SSF46785 46 136 3.63E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS12035 f527d90725f006ed1d8e3023be2a2481 154 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 105 120 1.2E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS12035 f527d90725f006ed1d8e3023be2a2481 154 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 77 88 1.2E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS12035 f527d90725f006ed1d8e3023be2a2481 154 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 90 105 1.2E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS12035 f527d90725f006ed1d8e3023be2a2481 154 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 1.2E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS12035 f527d90725f006ed1d8e3023be2a2481 154 Gene3D G3DSA:1.10.10.10 24 143 1.9E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS12035 f527d90725f006ed1d8e3023be2a2481 154 SMART SM00418 56 134 2.5E-23 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS12035 f527d90725f006ed1d8e3023be2a2481 154 Pfam PF12840 Helix-turn-helix domain 55 114 4.8E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS06735 f14770c09ab22493208b015363dbbfc5 280 Gene3D G3DSA:1.20.120.450 2 141 8.9E-12 T 28-03-2018 CFK41_RS06735 f14770c09ab22493208b015363dbbfc5 280 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 9 165 5.4E-14 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CFK41_RS06735 f14770c09ab22493208b015363dbbfc5 280 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 10 134 6.5E-18 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CFK41_RS06735 f14770c09ab22493208b015363dbbfc5 280 SUPERFAMILY SSF109854 5 139 1.98E-7 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CFK41_RS16290 effb58f32e9c9dcc9c67ff5f4b1910a9 640 SUPERFAMILY SSF53850 170 633 1.5E-46 T 28-03-2018 CFK41_RS16290 effb58f32e9c9dcc9c67ff5f4b1910a9 640 Gene3D G3DSA:3.40.190.10 307 638 4.9E-31 T 28-03-2018 CFK41_RS16290 effb58f32e9c9dcc9c67ff5f4b1910a9 640 Pfam PF13416 Bacterial extracellular solute-binding protein 294 500 2.6E-14 T 28-03-2018 CFK41_RS14945 5bf9eb445a3655cfa1c1c30e05adfd11 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 7.8E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS14945 5bf9eb445a3655cfa1c1c30e05adfd11 226 SUPERFAMILY SSF46689 4 82 4.46E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS14945 5bf9eb445a3655cfa1c1c30e05adfd11 226 Gene3D G3DSA:1.10.10.60 7 60 4.3E-17 T 28-03-2018 CFK41_RS14945 5bf9eb445a3655cfa1c1c30e05adfd11 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 1.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS14945 5bf9eb445a3655cfa1c1c30e05adfd11 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 1.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS14945 5bf9eb445a3655cfa1c1c30e05adfd11 226 Gene3D G3DSA:1.10.357.10 61 197 2.3E-9 T 28-03-2018 CFK41_RS14945 5bf9eb445a3655cfa1c1c30e05adfd11 226 SUPERFAMILY SSF48498 113 197 9.64E-5 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CFK41_RS12110 b64e26622f0a0dda37ecd7e0b8984bb8 371 Gene3D G3DSA:1.20.1630.10 55 340 3.8E-45 T 28-03-2018 CFK41_RS12110 b64e26622f0a0dda37ecd7e0b8984bb8 371 Pfam PF03916 Polysulphide reductase, NrfD 68 247 4.5E-19 T 28-03-2018 IPR005614 NrfD family CFK41_RS01030 a613cdf1f9288737c0b3bac31d84cf55 408 Gene3D G3DSA:3.40.640.10 52 311 2.2E-58 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS01030 a613cdf1f9288737c0b3bac31d84cf55 408 Gene3D G3DSA:3.90.1150.10 312 407 2.3E-19 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS01030 a613cdf1f9288737c0b3bac31d84cf55 408 Pfam PF00155 Aminotransferase class I and II 39 400 3.5E-58 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CFK41_RS01030 a613cdf1f9288737c0b3bac31d84cf55 408 SUPERFAMILY SSF53383 24 403 7.37E-99 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS01140 90b56204d227a44a896bd3c75fa1f064 239 Gene3D G3DSA:1.20.1080.10 1 239 1.6E-76 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CFK41_RS01140 90b56204d227a44a896bd3c75fa1f064 239 ProSitePatterns PS00221 MIP family signature. 62 70 - T 28-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CFK41_RS01140 90b56204d227a44a896bd3c75fa1f064 239 Pfam PF00230 Major intrinsic protein 6 235 4.0E-32 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CFK41_RS01140 90b56204d227a44a896bd3c75fa1f064 239 PRINTS PR00783 Major intrinsic protein family signature 172 194 3.1E-26 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CFK41_RS01140 90b56204d227a44a896bd3c75fa1f064 239 PRINTS PR00783 Major intrinsic protein family signature 219 239 3.1E-26 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CFK41_RS01140 90b56204d227a44a896bd3c75fa1f064 239 PRINTS PR00783 Major intrinsic protein family signature 89 108 3.1E-26 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CFK41_RS01140 90b56204d227a44a896bd3c75fa1f064 239 PRINTS PR00783 Major intrinsic protein family signature 3 22 3.1E-26 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CFK41_RS01140 90b56204d227a44a896bd3c75fa1f064 239 PRINTS PR00783 Major intrinsic protein family signature 144 162 3.1E-26 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CFK41_RS01140 90b56204d227a44a896bd3c75fa1f064 239 SUPERFAMILY SSF81338 4 235 2.62E-58 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CFK41_RS13370 7af378c8e4204d8a13b659bebbb0513b 205 PIRSF PIRSF016661 13 203 1.2E-39 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CFK41_RS13370 7af378c8e4204d8a13b659bebbb0513b 205 Pfam PF02632 BioY family 49 196 7.9E-35 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CFK41_RS03415 5d9f8bd3842022afdf3abf5af7df1df4 252 SUPERFAMILY SSF55811 54 227 6.77E-24 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CFK41_RS03415 5d9f8bd3842022afdf3abf5af7df1df4 252 Pfam PF00293 NUDIX domain 87 183 1.6E-10 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CFK41_RS03415 5d9f8bd3842022afdf3abf5af7df1df4 252 Gene3D G3DSA:3.90.79.10 44 231 6.2E-29 T 28-03-2018 CFK41_RS03535 a98b965e846fb90f3aa378c759b6ef4d 223 Gene3D G3DSA:3.40.1280.10 53 221 1.9E-46 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CFK41_RS03535 a98b965e846fb90f3aa378c759b6ef4d 223 Pfam PF00588 SpoU rRNA Methylase family 72 208 1.7E-23 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CFK41_RS03535 a98b965e846fb90f3aa378c759b6ef4d 223 SUPERFAMILY SSF75217 55 215 1.5E-37 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CFK41_RS03860 50c276b2c88309e1444cb4b3b8282a2f 366 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 18 354 4.1E-89 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CFK41_RS03860 50c276b2c88309e1444cb4b3b8282a2f 366 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 358 21.916 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CFK41_RS03860 50c276b2c88309e1444cb4b3b8282a2f 366 Pfam PF00953 Glycosyl transferase family 4 82 277 2.0E-35 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CFK41_RS16855 8454867bbc4dcf1b9befa669e7890bec 267 SUPERFAMILY SSF161098 8 264 2.71E-64 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS16855 8454867bbc4dcf1b9befa669e7890bec 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 261 8.9E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS16855 8454867bbc4dcf1b9befa669e7890bec 267 Gene3D G3DSA:1.10.3720.10 1 255 4.1E-39 T 28-03-2018 CFK41_RS15605 21d7be0facadba80483819e7230e2362 153 SUPERFAMILY SSF53927 2 151 5.52E-51 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CFK41_RS15605 21d7be0facadba80483819e7230e2362 153 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 55 92 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CFK41_RS15605 21d7be0facadba80483819e7230e2362 153 Gene3D G3DSA:3.40.140.10 1 153 6.3E-48 T 28-03-2018 CFK41_RS15605 21d7be0facadba80483819e7230e2362 153 Pfam PF14437 MafB19-like deaminase 3 151 4.7E-35 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CFK41_RS15605 21d7be0facadba80483819e7230e2362 153 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 7 151 46.596 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CFK41_RS13270 7d35e9ed364385ef788cb7976cebcb49 161 Gene3D G3DSA:3.40.630.30 2 160 2.5E-27 T 28-03-2018 CFK41_RS13270 7d35e9ed364385ef788cb7976cebcb49 161 Pfam PF00583 Acetyltransferase (GNAT) family 32 136 2.3E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS13270 7d35e9ed364385ef788cb7976cebcb49 161 SUPERFAMILY SSF55729 6 151 7.62E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS17225 0d0a48f671591c8816a185d500927aa6 483 Pfam PF02447 GntP family permease 273 481 1.6E-42 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CFK41_RS17225 0d0a48f671591c8816a185d500927aa6 483 Pfam PF02447 GntP family permease 4 211 4.6E-31 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CFK41_RS07490 21f5d73dbad5f656d18e142340d260c2 381 SUPERFAMILY SSF55781 33 160 1.41E-7 T 28-03-2018 IPR029016 GAF domain-like CFK41_RS07490 21f5d73dbad5f656d18e142340d260c2 381 SMART SM00387 286 380 2.2E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS07490 21f5d73dbad5f656d18e142340d260c2 381 SUPERFAMILY SSF55874 283 376 1.92E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS07490 21f5d73dbad5f656d18e142340d260c2 381 Gene3D G3DSA:3.30.565.10 176 381 3.6E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS07490 21f5d73dbad5f656d18e142340d260c2 381 Pfam PF07730 Histidine kinase 173 242 1.1E-11 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CFK41_RS07490 21f5d73dbad5f656d18e142340d260c2 381 Pfam PF13581 Histidine kinase-like ATPase domain 280 349 7.5E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS07490 21f5d73dbad5f656d18e142340d260c2 381 Gene3D G3DSA:3.30.450.40 16 161 1.2E-9 T 28-03-2018 IPR029016 GAF domain-like CFK41_RS14090 c0ef8fe9414eb8ad02c83b5eb3cbb093 292 Gene3D G3DSA:1.20.58.340 219 291 1.9E-10 T 28-03-2018 CFK41_RS14090 c0ef8fe9414eb8ad02c83b5eb3cbb093 292 Pfam PF01544 CorA-like Mg2+ transporter protein 118 286 4.8E-18 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CFK41_RS14090 c0ef8fe9414eb8ad02c83b5eb3cbb093 292 SUPERFAMILY SSF144083 230 280 7.32E-10 T 28-03-2018 CFK41_RS15600 9094268207a3b6aaa3492b47d4f53b28 369 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 24 365 3.8E-83 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CFK41_RS15600 9094268207a3b6aaa3492b47d4f53b28 369 Gene3D G3DSA:3.40.640.10 7 245 4.7E-34 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS15600 9094268207a3b6aaa3492b47d4f53b28 369 Gene3D G3DSA:3.90.1150.10 246 369 2.8E-33 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS15600 9094268207a3b6aaa3492b47d4f53b28 369 SUPERFAMILY SSF53383 42 366 2.95E-80 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS15600 9094268207a3b6aaa3492b47d4f53b28 369 PIRSF PIRSF001434 3 368 1.3E-106 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CFK41_RS14970 9fabdf8bf0267ff2f9eddda59805cb66 349 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 19 308 6.3E-53 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CFK41_RS14970 9fabdf8bf0267ff2f9eddda59805cb66 349 SUPERFAMILY SSF53686 19 325 1.83E-74 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CFK41_RS14970 9fabdf8bf0267ff2f9eddda59805cb66 349 Gene3D G3DSA:3.40.50.1100 36 152 2.5E-26 T 28-03-2018 CFK41_RS14970 9fabdf8bf0267ff2f9eddda59805cb66 349 Gene3D G3DSA:3.40.50.1100 153 323 5.8E-34 T 28-03-2018 CFK41_RS14970 9fabdf8bf0267ff2f9eddda59805cb66 349 TIGRFAM TIGR03945 PLP_SbnA_fam: 2,3-diaminopropionate biosynthesis protein SbnA 22 324 1.4E-106 T 28-03-2018 IPR023927 2,3-diaminopropionate biosynthesis protein SbnA CFK41_RS09280 0b8a36342eb1d5f70dff35e469ffbdf0 153 SUPERFAMILY SSF55811 9 144 1.07E-14 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CFK41_RS09280 0b8a36342eb1d5f70dff35e469ffbdf0 153 Gene3D G3DSA:3.90.79.10 4 149 1.8E-15 T 28-03-2018 CFK41_RS09280 0b8a36342eb1d5f70dff35e469ffbdf0 153 Pfam PF00293 NUDIX domain 23 128 3.4E-11 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CFK41_RS13420 891ff38cb6f283894cf84029cc4705f8 205 Pfam PF00574 Clp protease 19 186 2.3E-50 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CFK41_RS13420 891ff38cb6f283894cf84029cc4705f8 205 PRINTS PR00127 Clp protease catalytic subunit P signature 106 125 1.6E-24 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CFK41_RS13420 891ff38cb6f283894cf84029cc4705f8 205 PRINTS PR00127 Clp protease catalytic subunit P signature 54 74 1.6E-24 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CFK41_RS13420 891ff38cb6f283894cf84029cc4705f8 205 PRINTS PR00127 Clp protease catalytic subunit P signature 85 102 1.6E-24 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CFK41_RS13420 891ff38cb6f283894cf84029cc4705f8 205 PRINTS PR00127 Clp protease catalytic subunit P signature 163 182 1.6E-24 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CFK41_RS13420 891ff38cb6f283894cf84029cc4705f8 205 SUPERFAMILY SSF52096 19 187 1.09E-45 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CFK41_RS13420 891ff38cb6f283894cf84029cc4705f8 205 Gene3D G3DSA:3.90.226.10 16 188 2.1E-29 T 28-03-2018 CFK41_RS16450 7ca01399f42fa8fe623b66cb80859fc5 788 SMART SM01217 668 737 5.9E-32 T 28-03-2018 IPR026891 Fibronectin type III-like domain CFK41_RS16450 7ca01399f42fa8fe623b66cb80859fc5 788 PRINTS PR00133 Glycosyl hydrolase family 3 signature 172 188 1.4E-17 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS16450 7ca01399f42fa8fe623b66cb80859fc5 788 PRINTS PR00133 Glycosyl hydrolase family 3 signature 274 292 1.4E-17 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS16450 7ca01399f42fa8fe623b66cb80859fc5 788 PRINTS PR00133 Glycosyl hydrolase family 3 signature 126 145 1.4E-17 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS16450 7ca01399f42fa8fe623b66cb80859fc5 788 PRINTS PR00133 Glycosyl hydrolase family 3 signature 203 219 1.4E-17 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS16450 7ca01399f42fa8fe623b66cb80859fc5 788 Gene3D G3DSA:2.60.40.10 632 751 1.9E-36 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS16450 7ca01399f42fa8fe623b66cb80859fc5 788 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 27 353 8.8E-73 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS16450 7ca01399f42fa8fe623b66cb80859fc5 788 SUPERFAMILY SSF52279 393 634 2.62E-46 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CFK41_RS16450 7ca01399f42fa8fe623b66cb80859fc5 788 Gene3D G3DSA:3.40.50.1700 385 631 1.1E-67 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CFK41_RS16450 7ca01399f42fa8fe623b66cb80859fc5 788 SUPERFAMILY SSF51445 4 392 7.48E-95 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS16450 7ca01399f42fa8fe623b66cb80859fc5 788 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 393 631 1.5E-47 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CFK41_RS16450 7ca01399f42fa8fe623b66cb80859fc5 788 Gene3D G3DSA:3.20.20.300 11 384 1.5E-101 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS16450 7ca01399f42fa8fe623b66cb80859fc5 788 Pfam PF14310 Fibronectin type III-like domain 668 737 1.0E-22 T 28-03-2018 IPR026891 Fibronectin type III-like domain CFK41_RS03315 bb8bece3c3ae3c338f44cfd43fbd020d 308 Gene3D G3DSA:3.40.50.300 29 302 5.4E-41 T 28-03-2018 CFK41_RS03315 bb8bece3c3ae3c338f44cfd43fbd020d 308 Pfam PF00005 ABC transporter 79 209 4.2E-15 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS03315 bb8bece3c3ae3c338f44cfd43fbd020d 308 SUPERFAMILY SSF52540 73 270 7.25E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS03315 bb8bece3c3ae3c338f44cfd43fbd020d 308 SMART SM00382 87 259 1.7E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS14660 fd809cd38b4c14787e7c9d8503f555cf 507 SUPERFAMILY SSF53649 3 468 2.62E-111 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CFK41_RS14660 fd809cd38b4c14787e7c9d8503f555cf 507 ProSitePatterns PS00149 Sulfatases signature 2. 99 109 - T 28-03-2018 IPR024607 Sulfatase, conserved site CFK41_RS14660 fd809cd38b4c14787e7c9d8503f555cf 507 Gene3D G3DSA:3.30.1120.10 396 484 1.1E-16 T 28-03-2018 CFK41_RS14660 fd809cd38b4c14787e7c9d8503f555cf 507 Pfam PF16347 Domain of unknown function (DUF4976) 377 465 3.2E-12 T 28-03-2018 IPR032506 Domain of unknown function DUF4976 Reactome: R-HSA-2024096 CFK41_RS14660 fd809cd38b4c14787e7c9d8503f555cf 507 Pfam PF00884 Sulfatase 4 369 5.4E-54 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CFK41_RS14660 fd809cd38b4c14787e7c9d8503f555cf 507 Gene3D G3DSA:3.40.720.10 1 395 4.5E-76 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CFK41_RS14660 fd809cd38b4c14787e7c9d8503f555cf 507 ProSitePatterns PS00523 Sulfatases signature 1. 50 62 - T 28-03-2018 IPR024607 Sulfatase, conserved site CFK41_RS10965 c65e97f66998e3c2a24d0a8a68a14d0d 258 Pfam PF01636 Phosphotransferase enzyme family 31 99 1.8E-5 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CFK41_RS10965 c65e97f66998e3c2a24d0a8a68a14d0d 258 Pfam PF01636 Phosphotransferase enzyme family 114 186 9.4E-10 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CFK41_RS10965 c65e97f66998e3c2a24d0a8a68a14d0d 258 Gene3D G3DSA:1.10.510.10 32 191 2.6E-22 T 28-03-2018 CFK41_RS10965 c65e97f66998e3c2a24d0a8a68a14d0d 258 SUPERFAMILY SSF56112 31 211 4.96E-22 T 28-03-2018 IPR011009 Protein kinase-like domain CFK41_RS12340 46978f6619f5ce8a27c617a362114c65 791 SUPERFAMILY SSF52540 15 62 6.02E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS12340 46978f6619f5ce8a27c617a362114c65 791 SUPERFAMILY SSF52540 304 454 6.02E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS12340 46978f6619f5ce8a27c617a362114c65 791 Gene3D G3DSA:3.40.50.300 19 66 0.12 T 28-03-2018 CFK41_RS12340 46978f6619f5ce8a27c617a362114c65 791 Pfam PF00005 ABC transporter 502 709 8.7E-12 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS12340 46978f6619f5ce8a27c617a362114c65 791 SUPERFAMILY SSF52540 493 762 2.8E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS12340 46978f6619f5ce8a27c617a362114c65 791 Gene3D G3DSA:1.20.1580.10 101 371 1.6E-52 T 28-03-2018 CFK41_RS12340 46978f6619f5ce8a27c617a362114c65 791 Gene3D G3DSA:3.40.50.300 479 789 1.2E-55 T 28-03-2018 CFK41_RS15800 0dec78c71e3c9bc25703e798915bb299 313 Pfam PF02219 Methylenetetrahydrofolate reductase 17 299 9.2E-60 T 28-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CFK41_RS15800 0dec78c71e3c9bc25703e798915bb299 313 Gene3D G3DSA:3.20.20.220 8 303 2.9E-78 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CFK41_RS15800 0dec78c71e3c9bc25703e798915bb299 313 SUPERFAMILY SSF51730 17 300 2.75E-66 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CFK41_RS16960 92aa9a61f413b208597b0b42d1ada025 544 ProSitePatterns PS00211 ABC transporters family signature. 426 440 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS16960 92aa9a61f413b208597b0b42d1ada025 544 SUPERFAMILY SSF52540 21 253 6.06E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS16960 92aa9a61f413b208597b0b42d1ada025 544 SUPERFAMILY SSF52540 283 525 1.08E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS16960 92aa9a61f413b208597b0b42d1ada025 544 Gene3D G3DSA:3.40.50.300 4 275 3.7E-60 T 28-03-2018 CFK41_RS16960 92aa9a61f413b208597b0b42d1ada025 544 Gene3D G3DSA:3.40.50.300 279 542 3.2E-71 T 28-03-2018 CFK41_RS16960 92aa9a61f413b208597b0b42d1ada025 544 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 265 8.1E-4 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CFK41_RS16960 92aa9a61f413b208597b0b42d1ada025 544 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 505 537 7.4E-6 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CFK41_RS16960 92aa9a61f413b208597b0b42d1ada025 544 SMART SM00382 32 231 1.5E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS16960 92aa9a61f413b208597b0b42d1ada025 544 SMART SM00382 311 503 5.5E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS16960 92aa9a61f413b208597b0b42d1ada025 544 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS16960 92aa9a61f413b208597b0b42d1ada025 544 Pfam PF00005 ABC transporter 302 454 1.3E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS16960 92aa9a61f413b208597b0b42d1ada025 544 Pfam PF00005 ABC transporter 25 181 1.4E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS13670 384329ba034696e30cd5f6694ef4d015 288 Gene3D G3DSA:3.40.50.720 1 167 2.0E-22 T 28-03-2018 CFK41_RS13670 384329ba034696e30cd5f6694ef4d015 288 Gene3D G3DSA:1.10.1040.10 168 288 1.7E-17 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CFK41_RS13670 384329ba034696e30cd5f6694ef4d015 288 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 135 2.8E-22 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CFK41_RS13670 384329ba034696e30cd5f6694ef4d015 288 SUPERFAMILY SSF51735 1 134 4.69E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS13670 384329ba034696e30cd5f6694ef4d015 288 PIRSF PIRSF000103 1 288 3.3E-49 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CFK41_RS13670 384329ba034696e30cd5f6694ef4d015 288 SUPERFAMILY SSF48179 161 279 1.13E-10 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CFK41_RS06215 ede27084191740af3cec340cf69560c4 297 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 60 204 4.4E-43 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CFK41_RS06215 ede27084191740af3cec340cf69560c4 297 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 61 203 7.1E-43 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CFK41_RS17425 d6c9c472be8b3f65f4df55345683bd5e 200 Pfam PF12089 Transmembrane domain of unknown function (DUF3566) 83 199 8.6E-38 T 28-03-2018 IPR021949 Domain of unknown function DUF3566. transmembrane CFK41_RS09040 dc1c5e00518d0cf23de478c13d561bbd 164 Pfam PF12802 MarR family 42 103 2.1E-7 T 28-03-2018 CFK41_RS09040 dc1c5e00518d0cf23de478c13d561bbd 164 SUPERFAMILY SSF46785 10 152 5.66E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS09040 dc1c5e00518d0cf23de478c13d561bbd 164 Gene3D G3DSA:1.10.10.10 2 155 8.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS09040 dc1c5e00518d0cf23de478c13d561bbd 164 SMART SM00347 37 140 5.1E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS12160 d4814f7d680a390220bacacd35cc203b 195 Pfam PF01872 RibD C-terminal domain 11 177 8.3E-13 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CFK41_RS12160 d4814f7d680a390220bacacd35cc203b 195 Gene3D G3DSA:3.40.430.10 10 188 9.9E-25 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CFK41_RS12160 d4814f7d680a390220bacacd35cc203b 195 SUPERFAMILY SSF53597 9 182 3.93E-16 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CFK41_RS06060 adf7cfb0e28cb0099fb1f347debd260d 261 SUPERFAMILY SSF48008 116 253 4.45E-23 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS06060 adf7cfb0e28cb0099fb1f347debd260d 261 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 66 82 1.9E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS06060 adf7cfb0e28cb0099fb1f347debd260d 261 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 66 1.9E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS06060 adf7cfb0e28cb0099fb1f347debd260d 261 SUPERFAMILY SSF46785 24 107 9.24E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS06060 adf7cfb0e28cb0099fb1f347debd260d 261 Gene3D G3DSA:1.20.120.530 103 256 3.0E-23 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS06060 adf7cfb0e28cb0099fb1f347debd260d 261 Pfam PF00392 Bacterial regulatory proteins, gntR family 30 92 2.1E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS06060 adf7cfb0e28cb0099fb1f347debd260d 261 Gene3D G3DSA:1.10.10.10 22 99 1.2E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS06060 adf7cfb0e28cb0099fb1f347debd260d 261 SMART SM00895 118 249 7.0E-18 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS06060 adf7cfb0e28cb0099fb1f347debd260d 261 SMART SM00345 33 92 1.7E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS06060 adf7cfb0e28cb0099fb1f347debd260d 261 Pfam PF07729 FCD domain 119 248 8.3E-17 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS17075 9786f96fc3e45b8a4d4c303dba16577e 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 247 9.1E-52 T 28-03-2018 CFK41_RS17075 9786f96fc3e45b8a4d4c303dba16577e 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 194 0.0082 T 28-03-2018 CFK41_RS17075 9786f96fc3e45b8a4d4c303dba16577e 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 6.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17075 9786f96fc3e45b8a4d4c303dba16577e 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 6.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17075 9786f96fc3e45b8a4d4c303dba16577e 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 6.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17075 9786f96fc3e45b8a4d4c303dba16577e 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 4.4E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17075 9786f96fc3e45b8a4d4c303dba16577e 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 4.4E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17075 9786f96fc3e45b8a4d4c303dba16577e 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 4.4E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17075 9786f96fc3e45b8a4d4c303dba16577e 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 4.4E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17075 9786f96fc3e45b8a4d4c303dba16577e 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 4.4E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17075 9786f96fc3e45b8a4d4c303dba16577e 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 4.4E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS17075 9786f96fc3e45b8a4d4c303dba16577e 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CFK41_RS17075 9786f96fc3e45b8a4d4c303dba16577e 253 SUPERFAMILY SSF51735 9 249 3.64E-67 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS17075 9786f96fc3e45b8a4d4c303dba16577e 253 Gene3D G3DSA:3.40.50.720 13 253 2.2E-66 T 28-03-2018 CFK41_RS09285 45036d53db7816aff89f497420b18a85 411 Gene3D G3DSA:3.10.180.10 67 236 4.6E-5 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS09285 45036d53db7816aff89f497420b18a85 411 Gene3D G3DSA:3.10.180.10 290 398 0.0012 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS09690 999f813c42cab9bd36ba08623374e475 180 Pfam PF11292 Protein of unknown function (DUF3093) 27 164 2.2E-36 T 28-03-2018 IPR021443 Protein of unknown function DUF3093 CFK41_RS08365 b510c367d4684488bee5e0f58190a69a 163 PRINTS PR01576 Peptide deformylase signature 120 149 4.8E-20 T 28-03-2018 IPR023635 Peptide deformylase CFK41_RS08365 b510c367d4684488bee5e0f58190a69a 163 PRINTS PR01576 Peptide deformylase signature 101 119 4.8E-20 T 28-03-2018 IPR023635 Peptide deformylase CFK41_RS08365 b510c367d4684488bee5e0f58190a69a 163 PRINTS PR01576 Peptide deformylase signature 33 62 4.8E-20 T 28-03-2018 IPR023635 Peptide deformylase CFK41_RS08365 b510c367d4684488bee5e0f58190a69a 163 PRINTS PR01576 Peptide deformylase signature 89 100 4.8E-20 T 28-03-2018 IPR023635 Peptide deformylase CFK41_RS08365 b510c367d4684488bee5e0f58190a69a 163 Gene3D G3DSA:3.90.45.10 1 163 1.7E-46 T 28-03-2018 IPR023635 Peptide deformylase CFK41_RS08365 b510c367d4684488bee5e0f58190a69a 163 Pfam PF01327 Polypeptide deformylase 4 150 6.0E-36 T 28-03-2018 IPR023635 Peptide deformylase CFK41_RS08365 b510c367d4684488bee5e0f58190a69a 163 SUPERFAMILY SSF56420 2 160 4.06E-44 T 28-03-2018 IPR023635 Peptide deformylase CFK41_RS08365 b510c367d4684488bee5e0f58190a69a 163 PIRSF PIRSF004749 1 162 6.9E-36 T 28-03-2018 IPR023635 Peptide deformylase CFK41_RS08365 b510c367d4684488bee5e0f58190a69a 163 Hamap MF_00163 Peptide deformylase [def]. 2 162 23.75 T 28-03-2018 IPR023635 Peptide deformylase CFK41_RS15660 a9353863a88593ea4b7957fd0ffe517b 274 Pfam PF07859 alpha/beta hydrolase fold 51 236 9.2E-36 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CFK41_RS15660 a9353863a88593ea4b7957fd0ffe517b 274 Gene3D G3DSA:3.40.50.1820 9 270 7.8E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS15660 a9353863a88593ea4b7957fd0ffe517b 274 SUPERFAMILY SSF53474 15 243 8.03E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS09310 87dcf6473b5f1250730cb5cc866e2109 360 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 15 342 2.8E-104 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CFK41_RS09310 87dcf6473b5f1250730cb5cc866e2109 360 SUPERFAMILY SSF56796 7 354 1.96E-97 T 28-03-2018 CFK41_RS09310 87dcf6473b5f1250730cb5cc866e2109 360 PIRSF PIRSF001455 11 349 4.7E-93 T 28-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CFK41_RS09310 87dcf6473b5f1250730cb5cc866e2109 360 Gene3D G3DSA:1.20.1090.10 173 360 6.2E-59 T 28-03-2018 CFK41_RS09310 87dcf6473b5f1250730cb5cc866e2109 360 Gene3D G3DSA:3.40.50.1970 8 171 2.4E-40 T 28-03-2018 CFK41_RS09310 87dcf6473b5f1250730cb5cc866e2109 360 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 4 356 35.693 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CFK41_RS09310 87dcf6473b5f1250730cb5cc866e2109 360 Pfam PF01761 3-dehydroquinate synthase 68 323 3.2E-89 T 28-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CFK41_RS05085 bfc7b4e640d3643e4145b6d33427e8a9 100 SMART SM00530 16 71 1.5E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CFK41_RS05085 bfc7b4e640d3643e4145b6d33427e8a9 100 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 7 85 7.6E-32 T 28-03-2018 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 CFK41_RS05085 bfc7b4e640d3643e4145b6d33427e8a9 100 Gene3D G3DSA:1.10.260.40 1 98 1.4E-12 T 28-03-2018 CFK41_RS05085 bfc7b4e640d3643e4145b6d33427e8a9 100 SUPERFAMILY SSF47413 11 95 2.51E-27 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS05085 bfc7b4e640d3643e4145b6d33427e8a9 100 Pfam PF01381 Helix-turn-helix 24 70 8.7E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CFK41_RS02095 e8463d1d9d6aca4536f5b95cb90d34b6 507 Pfam PF00171 Aldehyde dehydrogenase family 28 494 3.7E-159 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CFK41_RS02095 e8463d1d9d6aca4536f5b95cb90d34b6 507 Gene3D G3DSA:3.40.309.10 280 481 1.6E-63 T 28-03-2018 CFK41_RS02095 e8463d1d9d6aca4536f5b95cb90d34b6 507 Gene3D G3DSA:3.40.605.10 8 279 1.7E-93 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CFK41_RS02095 e8463d1d9d6aca4536f5b95cb90d34b6 507 SUPERFAMILY SSF53720 16 499 7.46E-161 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CFK41_RS02095 e8463d1d9d6aca4536f5b95cb90d34b6 507 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 262 269 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CFK41_RS07910 c3800694b1ae268bbcabee20097b49f3 235 Pfam PF01925 Sulfite exporter TauE/SafE 2 219 2.0E-23 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CFK41_RS12800 b12ab8ec5592d6c7b60d68ab5a4536ae 384 Gene3D G3DSA:2.160.20.10 61 365 1.5E-16 T 28-03-2018 IPR012334 Pectin lyase fold CFK41_RS12800 b12ab8ec5592d6c7b60d68ab5a4536ae 384 Pfam PF01696 Adenovirus EB1 55K protein / large t-antigen 56 112 2.3E-5 T 28-03-2018 IPR002612 Adenovirus large t-antigen, E1B 55kDa protein CFK41_RS12800 b12ab8ec5592d6c7b60d68ab5a4536ae 384 SUPERFAMILY SSF51126 59 361 1.92E-14 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CFK41_RS12215 82682cdf9f781be9ecc42d7cd783079c 436 Pfam PF07690 Major Facilitator Superfamily 32 223 4.7E-18 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS12215 82682cdf9f781be9ecc42d7cd783079c 436 Pfam PF07690 Major Facilitator Superfamily 254 425 2.2E-8 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS12215 82682cdf9f781be9ecc42d7cd783079c 436 SUPERFAMILY SSF103473 26 427 6.63E-39 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS12215 82682cdf9f781be9ecc42d7cd783079c 436 Gene3D G3DSA:1.20.1250.20 234 429 6.4E-17 T 28-03-2018 CFK41_RS12215 82682cdf9f781be9ecc42d7cd783079c 436 Gene3D G3DSA:1.20.1250.20 21 214 8.0E-21 T 28-03-2018 CFK41_RS06050 e9d3565f9ab63e183bf7a40501650456 349 SUPERFAMILY SSF55811 186 312 2.17E-18 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CFK41_RS06050 e9d3565f9ab63e183bf7a40501650456 349 Gene3D G3DSA:3.90.79.10 146 348 1.1E-18 T 28-03-2018 CFK41_RS06050 e9d3565f9ab63e183bf7a40501650456 349 Gene3D G3DSA:3.40.50.300 3 145 6.1E-12 T 28-03-2018 CFK41_RS06050 e9d3565f9ab63e183bf7a40501650456 349 ProSitePatterns PS00893 Nudix box signature. 230 251 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CFK41_RS06050 e9d3565f9ab63e183bf7a40501650456 349 Pfam PF00293 NUDIX domain 210 309 3.3E-11 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CFK41_RS06050 e9d3565f9ab63e183bf7a40501650456 349 SUPERFAMILY SSF52540 6 141 8.29E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS15095 155d5df4ee876cbbf1ab3cf12ff458f6 478 Pfam PF00884 Sulfatase 10 355 6.3E-60 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CFK41_RS15095 155d5df4ee876cbbf1ab3cf12ff458f6 478 Gene3D G3DSA:3.40.720.10 7 386 3.8E-80 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CFK41_RS15095 155d5df4ee876cbbf1ab3cf12ff458f6 478 Gene3D G3DSA:3.30.1120.10 436 474 2.8E-5 T 28-03-2018 CFK41_RS15095 155d5df4ee876cbbf1ab3cf12ff458f6 478 ProSitePatterns PS00523 Sulfatases signature 1. 57 69 - T 28-03-2018 IPR024607 Sulfatase, conserved site CFK41_RS15095 155d5df4ee876cbbf1ab3cf12ff458f6 478 SUPERFAMILY SSF53649 9 408 4.94E-103 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CFK41_RS15095 155d5df4ee876cbbf1ab3cf12ff458f6 478 SUPERFAMILY SSF53649 435 467 4.94E-103 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CFK41_RS09580 d98acba7ec4b3bc46d51a80527dbd43e 251 Pfam PF00005 ABC transporter 23 174 1.6E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS09580 d98acba7ec4b3bc46d51a80527dbd43e 251 SMART SM00382 32 226 1.4E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS09580 d98acba7ec4b3bc46d51a80527dbd43e 251 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 246 1.7E-102 T 28-03-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 CFK41_RS09580 d98acba7ec4b3bc46d51a80527dbd43e 251 Gene3D G3DSA:3.40.50.300 1 250 6.5E-41 T 28-03-2018 CFK41_RS09580 d98acba7ec4b3bc46d51a80527dbd43e 251 SUPERFAMILY SSF52540 3 234 3.12E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS15090 db3ba4c6a760266ebc43dfb049bb5dd5 112 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 31 93 1.9E-6 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CFK41_RS15090 db3ba4c6a760266ebc43dfb049bb5dd5 112 SUPERFAMILY SSF101386 22 97 4.25E-16 T 28-03-2018 CFK41_RS15090 db3ba4c6a760266ebc43dfb049bb5dd5 112 Gene3D G3DSA:1.10.287.1080 1 97 2.2E-14 T 28-03-2018 CFK41_RS15365 7db0540d80a44e4f2870c0ebb88890c3 447 Gene3D G3DSA:3.40.50.10800 174 273 1.8E-27 T 28-03-2018 CFK41_RS15365 7db0540d80a44e4f2870c0ebb88890c3 447 Pfam PF02445 Quinolinate synthetase A protein 81 435 4.4E-107 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CFK41_RS15365 7db0540d80a44e4f2870c0ebb88890c3 447 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 76 436 2.7E-88 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CFK41_RS15365 7db0540d80a44e4f2870c0ebb88890c3 447 Gene3D G3DSA:3.40.50.10800 76 173 8.6E-17 T 28-03-2018 CFK41_RS15365 7db0540d80a44e4f2870c0ebb88890c3 447 Gene3D G3DSA:3.40.50.10800 300 417 6.2E-23 T 28-03-2018 CFK41_RS15365 7db0540d80a44e4f2870c0ebb88890c3 447 Hamap MF_00569 Quinolinate synthase A [nadA]. 74 436 54.088 T 28-03-2018 IPR023515 Quinolinate synthase A, type 3 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CFK41_RS15365 7db0540d80a44e4f2870c0ebb88890c3 447 SUPERFAMILY SSF142754 84 435 1.7E-93 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CFK41_RS09025 b5a84ae0226f0f9e9ab427441a418b36 308 SUPERFAMILY SSF103481 63 153 3.14E-14 T 28-03-2018 CFK41_RS09025 b5a84ae0226f0f9e9ab427441a418b36 308 SUPERFAMILY SSF103481 200 300 5.23E-13 T 28-03-2018 CFK41_RS09025 b5a84ae0226f0f9e9ab427441a418b36 308 Pfam PF00892 EamA-like transporter family 160 292 9.6E-17 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CFK41_RS09025 b5a84ae0226f0f9e9ab427441a418b36 308 Pfam PF00892 EamA-like transporter family 24 150 6.6E-16 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CFK41_RS17180 c412e17c4b36e519146ffbfa287c286f 233 SUPERFAMILY SSF46785 7 74 1.79E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS17180 c412e17c4b36e519146ffbfa287c286f 233 SMART SM00345 12 70 2.4E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS17180 c412e17c4b36e519146ffbfa287c286f 233 Pfam PF07729 FCD domain 81 214 1.0E-16 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS17180 c412e17c4b36e519146ffbfa287c286f 233 Gene3D G3DSA:1.20.120.530 70 228 2.2E-20 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS17180 c412e17c4b36e519146ffbfa287c286f 233 Gene3D G3DSA:1.10.10.10 1 69 2.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS17180 c412e17c4b36e519146ffbfa287c286f 233 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 70 6.3E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS17180 c412e17c4b36e519146ffbfa287c286f 233 SMART SM00895 81 215 2.5E-11 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS17180 c412e17c4b36e519146ffbfa287c286f 233 SUPERFAMILY SSF48008 79 219 4.45E-15 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS16445 13fff1338de824be53a5a7a48e989094 417 SUPERFAMILY SSF51445 25 362 1.23E-60 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS16445 13fff1338de824be53a5a7a48e989094 417 Gene3D G3DSA:3.20.20.80 29 369 8.3E-38 T 28-03-2018 CFK41_RS16445 13fff1338de824be53a5a7a48e989094 417 PRINTS PR00134 Glycosyl hydrolase family 10 signature 154 165 7.8E-9 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CFK41_RS16445 13fff1338de824be53a5a7a48e989094 417 PRINTS PR00134 Glycosyl hydrolase family 10 signature 226 238 7.8E-9 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CFK41_RS16445 13fff1338de824be53a5a7a48e989094 417 PRINTS PR00134 Glycosyl hydrolase family 10 signature 112 124 7.8E-9 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CFK41_RS16445 13fff1338de824be53a5a7a48e989094 417 PRINTS PR00134 Glycosyl hydrolase family 10 signature 203 214 7.8E-9 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CFK41_RS16445 13fff1338de824be53a5a7a48e989094 417 Pfam PF00331 Glycosyl hydrolase family 10 100 352 8.3E-33 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CFK41_RS16445 13fff1338de824be53a5a7a48e989094 417 SMART SM00633 92 357 2.2E-8 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CFK41_RS05005 791980afe37ace92320b672260b6d557 303 Pfam PF00294 pfkB family carbohydrate kinase 7 298 6.3E-43 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CFK41_RS05005 791980afe37ace92320b672260b6d557 303 Gene3D G3DSA:3.40.1190.20 4 303 1.0E-57 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS05005 791980afe37ace92320b672260b6d557 303 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 28 52 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CFK41_RS05005 791980afe37ace92320b672260b6d557 303 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 236 249 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CFK41_RS05005 791980afe37ace92320b672260b6d557 303 SUPERFAMILY SSF53613 4 299 1.05E-62 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS04315 d6041bccf0671ba470c32e2a918f238f 32 SMART SM01155 1 32 0.0037 T 28-03-2018 IPR013177 Domain of unknown function DUF1713 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04315 d6041bccf0671ba470c32e2a918f238f 32 Pfam PF08213 Mitochondrial domain of unknown function (DUF1713) 1 30 2.4E-6 T 28-03-2018 IPR013177 Domain of unknown function DUF1713 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS01050 134c16841204728aa53396d3ec942012 250 SUPERFAMILY SSF52540 9 243 8.95E-81 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS01050 134c16841204728aa53396d3ec942012 250 SMART SM00382 34 221 1.0E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS01050 134c16841204728aa53396d3ec942012 250 Pfam PF00005 ABC transporter 25 173 4.0E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS01050 134c16841204728aa53396d3ec942012 250 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS01050 134c16841204728aa53396d3ec942012 250 PIRSF PIRSF039085 6 249 4.1E-109 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CFK41_RS01050 134c16841204728aa53396d3ec942012 250 Gene3D G3DSA:3.40.50.300 5 249 4.0E-77 T 28-03-2018 CFK41_RS09830 c2e40ec678bc6aad193873943cf9c745 552 SUPERFAMILY SSF53098 15 197 2.41E-52 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CFK41_RS09830 c2e40ec678bc6aad193873943cf9c745 552 Pfam PF01541 GIY-YIG catalytic domain 223 294 4.7E-7 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CFK41_RS09830 c2e40ec678bc6aad193873943cf9c745 552 Gene3D G3DSA:1.20.5.140 173 190 6.7E-5 T 28-03-2018 CFK41_RS09830 c2e40ec678bc6aad193873943cf9c745 552 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 17 198 8.8E-30 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CFK41_RS09830 c2e40ec678bc6aad193873943cf9c745 552 Pfam PF00929 Exonuclease 22 179 7.9E-35 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CFK41_RS09830 c2e40ec678bc6aad193873943cf9c745 552 Gene3D G3DSA:3.40.1440.10 207 303 3.6E-15 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CFK41_RS09830 c2e40ec678bc6aad193873943cf9c745 552 Gene3D G3DSA:3.30.420.10 4 172 3.8E-45 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CFK41_RS09830 c2e40ec678bc6aad193873943cf9c745 552 SMART SM00479 20 188 5.8E-53 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CFK41_RS09830 c2e40ec678bc6aad193873943cf9c745 552 SMART SM00465 221 302 3.5E-6 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CFK41_RS09830 c2e40ec678bc6aad193873943cf9c745 552 SUPERFAMILY SSF82771 221 297 1.57E-11 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CFK41_RS13565 4460a39ca48daa03eec6abc2619513d8 342 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 22 310 2.0E-106 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CFK41_RS13565 4460a39ca48daa03eec6abc2619513d8 342 Gene3D G3DSA:3.40.50.720 139 294 5.4E-32 T 28-03-2018 CFK41_RS13565 4460a39ca48daa03eec6abc2619513d8 342 Gene3D G3DSA:3.30.1780.10 3 138 5.2E-34 T 28-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CFK41_RS13565 4460a39ca48daa03eec6abc2619513d8 342 SUPERFAMILY SSF51735 3 335 3.47E-98 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS16885 c084f1bc2364e73d42c55c80b40f9748 454 SUPERFAMILY SSF51445 22 361 9.48E-91 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS16885 c084f1bc2364e73d42c55c80b40f9748 454 Pfam PF01120 Alpha-L-fucosidase 23 357 2.3E-83 T 28-03-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS16885 c084f1bc2364e73d42c55c80b40f9748 454 Gene3D G3DSA:3.20.20.80 14 368 3.9E-90 T 28-03-2018 CFK41_RS16885 c084f1bc2364e73d42c55c80b40f9748 454 PRINTS PR00741 Glycosyl hydrolase family 29 signature 214 230 3.3E-26 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS16885 c084f1bc2364e73d42c55c80b40f9748 454 PRINTS PR00741 Glycosyl hydrolase family 29 signature 84 99 3.3E-26 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS16885 c084f1bc2364e73d42c55c80b40f9748 454 PRINTS PR00741 Glycosyl hydrolase family 29 signature 311 332 3.3E-26 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS16885 c084f1bc2364e73d42c55c80b40f9748 454 PRINTS PR00741 Glycosyl hydrolase family 29 signature 123 139 3.3E-26 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS16885 c084f1bc2364e73d42c55c80b40f9748 454 PRINTS PR00741 Glycosyl hydrolase family 29 signature 344 366 3.3E-26 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS16885 c084f1bc2364e73d42c55c80b40f9748 454 PRINTS PR00741 Glycosyl hydrolase family 29 signature 242 263 3.3E-26 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS16885 c084f1bc2364e73d42c55c80b40f9748 454 SMART SM00812 10 409 1.6E-124 T 28-03-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CFK41_RS10705 af9b43b2a0b33217166717a9305ee7a8 211 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 13 207 3.2E-56 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 CFK41_RS10705 af9b43b2a0b33217166717a9305ee7a8 211 Pfam PF01300 Telomere recombination 29 204 2.0E-41 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 CFK41_RS10705 af9b43b2a0b33217166717a9305ee7a8 211 Gene3D G3DSA:3.90.870.10 7 211 3.1E-58 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CFK41_RS10705 af9b43b2a0b33217166717a9305ee7a8 211 SUPERFAMILY SSF55821 8 209 6.71E-60 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CFK41_RS05285 9e2b6ff108a039a27a85a3ef355b4450 287 Gene3D G3DSA:3.40.190.10 144 229 2.9E-20 T 28-03-2018 CFK41_RS05285 9e2b6ff108a039a27a85a3ef355b4450 287 Gene3D G3DSA:3.40.190.10 38 143 1.9E-27 T 28-03-2018 CFK41_RS05285 9e2b6ff108a039a27a85a3ef355b4450 287 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 42 258 7.5E-46 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CFK41_RS05285 9e2b6ff108a039a27a85a3ef355b4450 287 SUPERFAMILY SSF53850 1 260 2.38E-53 T 28-03-2018 CFK41_RS05285 9e2b6ff108a039a27a85a3ef355b4450 287 SMART SM00062 41 270 2.4E-57 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CFK41_RS01945 476464915a396fb7559d7fe563069990 286 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 196 280 2.3E-10 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CFK41_RS01945 476464915a396fb7559d7fe563069990 286 SUPERFAMILY SSF52794 196 283 1.15E-12 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CFK41_RS01945 476464915a396fb7559d7fe563069990 286 Gene3D G3DSA:3.40.50.2300 191 285 9.2E-14 T 28-03-2018 CFK41_RS01945 476464915a396fb7559d7fe563069990 286 Gene3D G3DSA:3.40.930.10 2 148 1.0E-32 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CFK41_RS01945 476464915a396fb7559d7fe563069990 286 SUPERFAMILY SSF55804 3 146 3.27E-33 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CFK41_RS01945 476464915a396fb7559d7fe563069990 286 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 7 146 6.3E-29 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CFK41_RS15555 8c2a92a526a7132eaeb9b1f8bd97d6e4 281 PIRSF PIRSF002854 6 281 5.4E-89 T 28-03-2018 IPR004872 Lipoprotein NlpA family CFK41_RS15555 8c2a92a526a7132eaeb9b1f8bd97d6e4 281 SUPERFAMILY SSF53850 41 281 1.28E-68 T 28-03-2018 CFK41_RS15555 8c2a92a526a7132eaeb9b1f8bd97d6e4 281 Gene3D G3DSA:3.40.190.10 39 136 5.0E-17 T 28-03-2018 CFK41_RS15555 8c2a92a526a7132eaeb9b1f8bd97d6e4 281 Gene3D G3DSA:3.40.190.10 137 281 7.7E-47 T 28-03-2018 CFK41_RS15555 8c2a92a526a7132eaeb9b1f8bd97d6e4 281 Pfam PF03180 NLPA lipoprotein 42 281 7.1E-78 T 28-03-2018 IPR004872 Lipoprotein NlpA family CFK41_RS03635 15a918669e496c7c8e0d53bcabf4a6ba 241 Gene3D G3DSA:3.40.50.720 2 237 4.9E-51 T 28-03-2018 CFK41_RS03635 15a918669e496c7c8e0d53bcabf4a6ba 241 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CFK41_RS03635 15a918669e496c7c8e0d53bcabf4a6ba 241 SUPERFAMILY SSF51735 9 229 3.43E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS03635 15a918669e496c7c8e0d53bcabf4a6ba 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.3E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03635 15a918669e496c7c8e0d53bcabf4a6ba 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.3E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03635 15a918669e496c7c8e0d53bcabf4a6ba 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.3E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03635 15a918669e496c7c8e0d53bcabf4a6ba 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.3E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03635 15a918669e496c7c8e0d53bcabf4a6ba 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 224 1.3E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03635 15a918669e496c7c8e0d53bcabf4a6ba 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 1.3E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03635 15a918669e496c7c8e0d53bcabf4a6ba 241 Pfam PF00106 short chain dehydrogenase 14 199 1.1E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS03635 15a918669e496c7c8e0d53bcabf4a6ba 241 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 13 203 1.0E-4 T 28-03-2018 CFK41_RS11825 efbf08cdb259e9d4cadab4dc66b80e1e 301 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 257 283 - T 28-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 CFK41_RS11825 efbf08cdb259e9d4cadab4dc66b80e1e 301 Pfam PF01148 Cytidylyltransferase family 45 298 2.2E-48 T 28-03-2018 CFK41_RS05630 ff513b93fa3299d1a2766f5ecaee1925 597 Gene3D G3DSA:3.40.50.1700 442 588 7.3E-9 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CFK41_RS05630 ff513b93fa3299d1a2766f5ecaee1925 597 SUPERFAMILY SSF51445 2 415 2.11E-80 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS05630 ff513b93fa3299d1a2766f5ecaee1925 597 SUPERFAMILY SSF52279 416 587 3.14E-14 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CFK41_RS05630 ff513b93fa3299d1a2766f5ecaee1925 597 Gene3D G3DSA:3.20.20.300 1 399 8.1E-91 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS05630 ff513b93fa3299d1a2766f5ecaee1925 597 PRINTS PR00133 Glycosyl hydrolase family 3 signature 171 187 3.4E-13 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS05630 ff513b93fa3299d1a2766f5ecaee1925 597 PRINTS PR00133 Glycosyl hydrolase family 3 signature 125 144 3.4E-13 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS05630 ff513b93fa3299d1a2766f5ecaee1925 597 PRINTS PR00133 Glycosyl hydrolase family 3 signature 290 308 3.4E-13 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS05630 ff513b93fa3299d1a2766f5ecaee1925 597 PRINTS PR00133 Glycosyl hydrolase family 3 signature 206 222 3.4E-13 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS05630 ff513b93fa3299d1a2766f5ecaee1925 597 Gene3D G3DSA:3.40.50.1700 400 441 0.12 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CFK41_RS05630 ff513b93fa3299d1a2766f5ecaee1925 597 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 24 376 6.5E-47 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS11015 61e2ba05d898efda2e66ab740d66372a 411 Pfam PF00534 Glycosyl transferases group 1 222 369 9.9E-27 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CFK41_RS11015 61e2ba05d898efda2e66ab740d66372a 411 Gene3D G3DSA:3.40.50.2000 22 214 1.2E-21 T 28-03-2018 CFK41_RS11015 61e2ba05d898efda2e66ab740d66372a 411 Gene3D G3DSA:3.40.50.2000 215 379 1.9E-37 T 28-03-2018 CFK41_RS11015 61e2ba05d898efda2e66ab740d66372a 411 Pfam PF13439 Glycosyltransferase Family 4 26 209 1.7E-31 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CFK41_RS11015 61e2ba05d898efda2e66ab740d66372a 411 SUPERFAMILY SSF53756 25 402 7.02E-75 T 28-03-2018 CFK41_RS15980 62edf26897a7119bf5ab7dc340a8b1f7 339 SUPERFAMILY SSF75005 31 319 3.14E-76 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CFK41_RS15980 62edf26897a7119bf5ab7dc340a8b1f7 339 Gene3D G3DSA:2.115.10.20 30 336 6.7E-73 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CFK41_RS15980 62edf26897a7119bf5ab7dc340a8b1f7 339 Pfam PF04616 Glycosyl hydrolases family 43 38 320 5.2E-64 T 28-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 CFK41_RS14790 2ee0b9bf671bb34f31333dd26768411f 76 Gene3D G3DSA:3.30.110.40 1 74 1.3E-14 T 28-03-2018 IPR001455 TusA-like domain CFK41_RS14790 2ee0b9bf671bb34f31333dd26768411f 76 Pfam PF01206 Sulfurtransferase TusA 5 74 6.1E-15 T 28-03-2018 IPR001455 TusA-like domain CFK41_RS14790 2ee0b9bf671bb34f31333dd26768411f 76 SUPERFAMILY SSF64307 3 75 6.02E-18 T 28-03-2018 IPR001455 TusA-like domain CFK41_RS01305 5cfadf7c8ece4fd2ed8db8eaf2519199 450 SUPERFAMILY SSF51735 3 160 9.36E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS01305 5cfadf7c8ece4fd2ed8db8eaf2519199 450 Gene3D G3DSA:3.30.360.10 148 439 1.5E-45 T 28-03-2018 CFK41_RS01305 5cfadf7c8ece4fd2ed8db8eaf2519199 450 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 143 225 1.2E-16 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CFK41_RS01305 5cfadf7c8ece4fd2ed8db8eaf2519199 450 Gene3D G3DSA:3.40.50.720 1 147 6.2E-31 T 28-03-2018 CFK41_RS01305 5cfadf7c8ece4fd2ed8db8eaf2519199 450 SUPERFAMILY SSF55347 272 335 1.64E-26 T 28-03-2018 CFK41_RS01305 5cfadf7c8ece4fd2ed8db8eaf2519199 450 SUPERFAMILY SSF55347 134 219 1.64E-26 T 28-03-2018 CFK41_RS01305 5cfadf7c8ece4fd2ed8db8eaf2519199 450 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 129 6.0E-16 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS01475 236e7577acadf8965003049f81ab0c33 332 SUPERFAMILY SSF53474 41 330 2.15E-51 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS01475 236e7577acadf8965003049f81ab0c33 332 Pfam PF07859 alpha/beta hydrolase fold 140 309 1.8E-29 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CFK41_RS01475 236e7577acadf8965003049f81ab0c33 332 Pfam PF07859 alpha/beta hydrolase fold 77 117 6.8E-9 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CFK41_RS01475 236e7577acadf8965003049f81ab0c33 332 Gene3D G3DSA:3.40.50.1820 5 332 1.5E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS17070 8ef7ddc9783e4af3fbf24c830f8a74ec 448 Pfam PF07690 Major Facilitator Superfamily 38 402 2.5E-46 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS17070 8ef7ddc9783e4af3fbf24c830f8a74ec 448 Gene3D G3DSA:1.20.1250.20 245 446 4.9E-22 T 28-03-2018 CFK41_RS17070 8ef7ddc9783e4af3fbf24c830f8a74ec 448 Gene3D G3DSA:1.20.1250.20 23 232 5.4E-34 T 28-03-2018 CFK41_RS17070 8ef7ddc9783e4af3fbf24c830f8a74ec 448 SUPERFAMILY SSF103473 20 441 3.4E-80 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS15710 6a9d74cc3ba5c0c834839cd9f0596344 108 Gene3D G3DSA:3.40.630.30 11 106 1.5E-19 T 28-03-2018 CFK41_RS15710 6a9d74cc3ba5c0c834839cd9f0596344 108 SUPERFAMILY SSF55729 16 101 1.42E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS15710 6a9d74cc3ba5c0c834839cd9f0596344 108 Pfam PF14542 GCN5-related N-acetyl-transferase 26 99 6.9E-20 T 28-03-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase CFK41_RS03130 83b8da97b9ab6efabea4999b3c9a3812 296 Gene3D G3DSA:2.130.10.150 24 134 1.1E-16 T 28-03-2018 CFK41_RS03130 83b8da97b9ab6efabea4999b3c9a3812 296 Pfam PF00400 WD domain, G-beta repeat 67 111 5.7E-9 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CFK41_RS03130 83b8da97b9ab6efabea4999b3c9a3812 296 SMART SM00320 66 111 2.9E-10 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CFK41_RS03130 83b8da97b9ab6efabea4999b3c9a3812 296 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 98 112 - T 28-03-2018 IPR019775 WD40 repeat, conserved site CFK41_RS03130 83b8da97b9ab6efabea4999b3c9a3812 296 SUPERFAMILY SSF50998 236 287 2.12E-26 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CFK41_RS03130 83b8da97b9ab6efabea4999b3c9a3812 296 SUPERFAMILY SSF50998 46 195 2.12E-26 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CFK41_RS03130 83b8da97b9ab6efabea4999b3c9a3812 296 Gene3D G3DSA:2.130.10.10 135 293 3.5E-13 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CFK41_RS15265 0fcaf37935cf727ac0c015aad21ba4fe 446 SUPERFAMILY SSF51230 4 83 7.07E-25 T 28-03-2018 IPR011053 Single hybrid motif CFK41_RS15265 0fcaf37935cf727ac0c015aad21ba4fe 446 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CFK41_RS15265 0fcaf37935cf727ac0c015aad21ba4fe 446 SUPERFAMILY SSF47005 134 176 4.05E-9 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CFK41_RS15265 0fcaf37935cf727ac0c015aad21ba4fe 446 Gene3D G3DSA:3.30.559.10 213 446 7.3E-52 T 28-03-2018 CFK41_RS15265 0fcaf37935cf727ac0c015aad21ba4fe 446 Gene3D G3DSA:4.10.320.10 133 183 6.3E-14 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CFK41_RS15265 0fcaf37935cf727ac0c015aad21ba4fe 446 Pfam PF02817 e3 binding domain 137 171 6.9E-11 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CFK41_RS15265 0fcaf37935cf727ac0c015aad21ba4fe 446 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 232 445 2.0E-42 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CFK41_RS15265 0fcaf37935cf727ac0c015aad21ba4fe 446 Pfam PF00364 Biotin-requiring enzyme 6 75 8.0E-20 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CFK41_RS15265 0fcaf37935cf727ac0c015aad21ba4fe 446 SUPERFAMILY SSF52777 232 445 2.22E-44 T 28-03-2018 CFK41_RS15265 0fcaf37935cf727ac0c015aad21ba4fe 446 Gene3D G3DSA:2.40.50.100 6 80 3.5E-19 T 28-03-2018 CFK41_RS04035 ec2ff5c0d4797b1e911128860700653f 130 Pfam PF06339 Ectoine synthase 1 125 1.1E-57 T 28-03-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CFK41_RS04035 ec2ff5c0d4797b1e911128860700653f 130 Hamap MF_01255 L-ectoine synthase [ectC]. 1 127 37.736 T 28-03-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CFK41_RS04035 ec2ff5c0d4797b1e911128860700653f 130 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 1 117 1.0E-39 T 28-03-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CFK41_RS04035 ec2ff5c0d4797b1e911128860700653f 130 Gene3D G3DSA:2.60.120.10 7 128 3.3E-14 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CFK41_RS04035 ec2ff5c0d4797b1e911128860700653f 130 SUPERFAMILY SSF51182 1 125 1.0E-18 T 28-03-2018 IPR011051 RmlC-like cupin domain CFK41_RS02810 44b3670db4a52ae3a1d12eb32dca4fb1 450 Gene3D G3DSA:1.20.1250.20 239 443 1.6E-12 T 28-03-2018 CFK41_RS02810 44b3670db4a52ae3a1d12eb32dca4fb1 450 Pfam PF07690 Major Facilitator Superfamily 46 388 2.2E-24 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS02810 44b3670db4a52ae3a1d12eb32dca4fb1 450 Gene3D G3DSA:1.20.1250.20 23 229 2.3E-21 T 28-03-2018 CFK41_RS02810 44b3670db4a52ae3a1d12eb32dca4fb1 450 SUPERFAMILY SSF103473 40 435 7.98E-46 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS14630 a0191f1b811596e1ea6913791cf7bc8e 131 Gene3D G3DSA:3.40.630.30 11 115 8.9E-13 T 28-03-2018 CFK41_RS14630 a0191f1b811596e1ea6913791cf7bc8e 131 SUPERFAMILY SSF55729 16 108 2.51E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS14630 a0191f1b811596e1ea6913791cf7bc8e 131 Pfam PF14542 GCN5-related N-acetyl-transferase 26 106 5.2E-18 T 28-03-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase CFK41_RS07650 38a2739135e836230311ed32b1238251 320 SUPERFAMILY SSF48239 78 319 1.88E-11 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CFK41_RS07650 38a2739135e836230311ed32b1238251 320 Gene3D G3DSA:1.50.10.20 24 231 3.4E-5 T 28-03-2018 CFK41_RS07650 38a2739135e836230311ed32b1238251 320 Gene3D G3DSA:1.50.10.20 232 320 9.2E-5 T 28-03-2018 CFK41_RS03470 80a830624aa66e4a545d84339dfbc645 526 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 234 240 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CFK41_RS03470 80a830624aa66e4a545d84339dfbc645 526 Gene3D G3DSA:3.40.50.150 319 473 0.15 T 28-03-2018 CFK41_RS03470 80a830624aa66e4a545d84339dfbc645 526 Gene3D G3DSA:3.40.50.150 129 318 1.8E-29 T 28-03-2018 CFK41_RS03470 80a830624aa66e4a545d84339dfbc645 526 Pfam PF05175 Methyltransferase small domain 157 241 3.6E-16 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CFK41_RS03470 80a830624aa66e4a545d84339dfbc645 526 SUPERFAMILY SSF53335 158 312 1.28E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS05390 0e7f7a8c01171ee5fa242ca6c2ef8e09 114 Gene3D G3DSA:3.40.50.620 55 114 3.2E-10 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS05390 0e7f7a8c01171ee5fa242ca6c2ef8e09 114 SUPERFAMILY SSF52402 2 113 1.09E-12 T 28-03-2018 CFK41_RS05390 0e7f7a8c01171ee5fa242ca6c2ef8e09 114 PRINTS PR01438 Universal stress protein signature 1 9 6.7E-6 T 28-03-2018 IPR006015 Universal stress protein A CFK41_RS05390 0e7f7a8c01171ee5fa242ca6c2ef8e09 114 PRINTS PR01438 Universal stress protein signature 91 113 6.7E-6 T 28-03-2018 IPR006015 Universal stress protein A CFK41_RS05390 0e7f7a8c01171ee5fa242ca6c2ef8e09 114 PRINTS PR01438 Universal stress protein signature 73 85 6.7E-6 T 28-03-2018 IPR006015 Universal stress protein A CFK41_RS05390 0e7f7a8c01171ee5fa242ca6c2ef8e09 114 Gene3D G3DSA:3.40.50.620 1 54 0.25 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS05390 0e7f7a8c01171ee5fa242ca6c2ef8e09 114 Pfam PF00582 Universal stress protein family 54 113 7.6E-10 T 28-03-2018 IPR006016 UspA GO:0006950 CFK41_RS05465 818fe07b0f8a3c2aa34158e79acc399c 216 SMART SM00986 37 202 0.0018 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CFK41_RS05465 818fe07b0f8a3c2aa34158e79acc399c 216 SMART SM00987 37 202 0.0018 T 28-03-2018 CFK41_RS05465 818fe07b0f8a3c2aa34158e79acc399c 216 Pfam PF03167 Uracil DNA glycosylase superfamily 43 204 9.9E-20 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CFK41_RS05465 818fe07b0f8a3c2aa34158e79acc399c 216 SUPERFAMILY SSF52141 40 205 8.28E-32 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CFK41_RS05465 818fe07b0f8a3c2aa34158e79acc399c 216 Gene3D G3DSA:3.40.470.10 41 215 4.0E-40 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CFK41_RS11030 9d3f245a4decb4d42859d3fa78603da8 349 Gene3D G3DSA:1.10.4080.10 9 337 6.2E-59 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CFK41_RS11030 9d3f245a4decb4d42859d3fa78603da8 349 SUPERFAMILY SSF101478 13 333 6.54E-42 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CFK41_RS11030 9d3f245a4decb4d42859d3fa78603da8 349 Pfam PF03747 ADP-ribosylglycohydrolase 18 310 3.8E-45 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CFK41_RS14720 48fec7a996b3d738586afa83de282f7d 356 Pfam PF02126 Phosphotriesterase family 15 351 2.1E-42 T 28-03-2018 IPR001559 Phosphotriesterase GO:0008270|GO:0009056 CFK41_RS14720 48fec7a996b3d738586afa83de282f7d 356 Gene3D G3DSA:3.20.20.140 5 356 3.0E-51 T 28-03-2018 CFK41_RS14720 48fec7a996b3d738586afa83de282f7d 356 SUPERFAMILY SSF51556 8 45 4.63E-65 T 28-03-2018 IPR032466 Metal-dependent hydrolase CFK41_RS14720 48fec7a996b3d738586afa83de282f7d 356 SUPERFAMILY SSF51556 72 352 4.63E-65 T 28-03-2018 IPR032466 Metal-dependent hydrolase CFK41_RS02915 f7acde90099a384a4849f1412c5896f3 568 Gene3D G3DSA:3.30.43.10 56 168 9.5E-13 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CFK41_RS02915 f7acde90099a384a4849f1412c5896f3 568 Pfam PF01565 FAD binding domain 114 253 6.3E-34 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CFK41_RS02915 f7acde90099a384a4849f1412c5896f3 568 SUPERFAMILY SSF56176 65 290 3.92E-46 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CFK41_RS02915 f7acde90099a384a4849f1412c5896f3 568 Gene3D G3DSA:3.30.465.10 169 310 4.1E-30 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CFK41_RS02915 f7acde90099a384a4849f1412c5896f3 568 Pfam PF02913 FAD linked oxidases, C-terminal domain 293 565 5.4E-28 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CFK41_RS02915 f7acde90099a384a4849f1412c5896f3 568 SUPERFAMILY SSF55103 376 565 9.29E-31 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CFK41_RS02915 f7acde90099a384a4849f1412c5896f3 568 SUPERFAMILY SSF55103 271 341 9.29E-31 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CFK41_RS02915 f7acde90099a384a4849f1412c5896f3 568 Gene3D G3DSA:1.10.45.10 527 565 8.2E-5 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CFK41_RS12195 8ed58bac19113d8538a21deca628d245 234 SUPERFAMILY SSF53335 29 162 1.66E-29 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS12195 8ed58bac19113d8538a21deca628d245 234 Gene3D G3DSA:3.40.50.150 9 234 2.0E-28 T 28-03-2018 CFK41_RS12195 8ed58bac19113d8538a21deca628d245 234 Pfam PF13649 Methyltransferase domain 48 144 3.2E-17 T 28-03-2018 CFK41_RS16350 81a8b133bca5805832b91359d9b6da99 312 Gene3D G3DSA:1.20.58.370 20 64 1.6E-7 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CFK41_RS16350 81a8b133bca5805832b91359d9b6da99 312 SUPERFAMILY SSF161098 74 302 5.89E-59 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS16350 81a8b133bca5805832b91359d9b6da99 312 Gene3D G3DSA:1.10.3720.10 81 312 5.3E-44 T 28-03-2018 CFK41_RS16350 81a8b133bca5805832b91359d9b6da99 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 308 8.3E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS10450 9df7b169af8fd0b48a555041a3e3b3f7 109 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 107 8.0E-20 T 28-03-2018 IPR024412 Lsr2 CFK41_RS10450 9df7b169af8fd0b48a555041a3e3b3f7 109 Pfam PF11774 Lsr2 1 106 5.6E-38 T 28-03-2018 IPR024412 Lsr2 CFK41_RS02720 7a21650f9d6a4c4d655b9c7a57bc3c5d 536 Pfam PF13416 Bacterial extracellular solute-binding protein 81 392 8.4E-13 T 28-03-2018 CFK41_RS02720 7a21650f9d6a4c4d655b9c7a57bc3c5d 536 Gene3D G3DSA:3.40.190.10 190 536 2.7E-38 T 28-03-2018 CFK41_RS02720 7a21650f9d6a4c4d655b9c7a57bc3c5d 536 SUPERFAMILY SSF53850 26 534 1.15E-73 T 28-03-2018 CFK41_RS13920 427785ede63d906ccaa21b7da3578f9f 115 SUPERFAMILY SSF51278 10 104 4.58E-31 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CFK41_RS13920 427785ede63d906ccaa21b7da3578f9f 115 Gene3D G3DSA:2.10.150.10 9 110 1.2E-33 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CFK41_RS13920 427785ede63d906ccaa21b7da3578f9f 115 Pfam PF00699 Urease beta subunit 10 106 2.0E-31 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CFK41_RS02190 83ad7d53f420d8d9816350e35a65f784 451 Pfam PF13416 Bacterial extracellular solute-binding protein 67 381 9.4E-30 T 28-03-2018 CFK41_RS02190 83ad7d53f420d8d9816350e35a65f784 451 Gene3D G3DSA:3.40.190.10 33 204 2.7E-32 T 28-03-2018 CFK41_RS02190 83ad7d53f420d8d9816350e35a65f784 451 Gene3D G3DSA:3.40.190.10 222 383 0.052 T 28-03-2018 CFK41_RS02190 83ad7d53f420d8d9816350e35a65f784 451 SUPERFAMILY SSF53850 49 445 6.42E-55 T 28-03-2018 CFK41_RS12635 20e36ff24d607764828f33da13f3bd78 145 Gene3D G3DSA:3.90.1170.40 2 144 5.1E-49 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CFK41_RS12635 20e36ff24d607764828f33da13f3bd78 145 SUPERFAMILY SSF54690 11 142 5.89E-42 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CFK41_RS12635 20e36ff24d607764828f33da13f3bd78 145 Pfam PF02391 MoaE protein 13 124 4.5E-35 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CFK41_RS13580 5fcb98ea490bc5a714cebdc0b0da5ea5 347 Gene3D G3DSA:3.40.50.1980 57 180 8.5E-27 T 28-03-2018 CFK41_RS13580 5fcb98ea490bc5a714cebdc0b0da5ea5 347 SUPERFAMILY SSF53807 57 334 4.71E-48 T 28-03-2018 CFK41_RS13580 5fcb98ea490bc5a714cebdc0b0da5ea5 347 Pfam PF01497 Periplasmic binding protein 78 317 2.9E-20 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CFK41_RS13580 5fcb98ea490bc5a714cebdc0b0da5ea5 347 Gene3D G3DSA:3.40.50.1980 181 347 3.1E-26 T 28-03-2018 CFK41_RS01630 1d1ac5df125138ad6c8c47ba53e8f929 305 Gene3D G3DSA:2.115.10.20 5 300 9.2E-53 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CFK41_RS01630 1d1ac5df125138ad6c8c47ba53e8f929 305 Pfam PF04616 Glycosyl hydrolases family 43 7 293 4.4E-39 T 28-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 CFK41_RS01630 1d1ac5df125138ad6c8c47ba53e8f929 305 SUPERFAMILY SSF75005 7 291 8.25E-51 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CFK41_RS13925 fa5d9155eb46fffeff28da719ad6a460 100 Pfam PF00547 Urease, gamma subunit 1 99 2.0E-41 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CFK41_RS13925 fa5d9155eb46fffeff28da719ad6a460 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 7.0E-30 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CFK41_RS13925 fa5d9155eb46fffeff28da719ad6a460 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 100 3.8E-40 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CFK41_RS13925 fa5d9155eb46fffeff28da719ad6a460 100 SUPERFAMILY SSF54111 1 99 1.14E-39 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CFK41_RS13925 fa5d9155eb46fffeff28da719ad6a460 100 Gene3D G3DSA:3.30.280.10 2 99 5.4E-42 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CFK41_RS11395 f8a93c01046d063f673524909b77c258 563 Gene3D G3DSA:3.40.50.10490 3 149 1.3E-39 T 28-03-2018 CFK41_RS11395 f8a93c01046d063f673524909b77c258 563 Gene3D G3DSA:3.40.50.10490 150 274 6.1E-51 T 28-03-2018 CFK41_RS11395 f8a93c01046d063f673524909b77c258 563 Gene3D G3DSA:1.10.1390.10 525 563 6.0E-19 T 28-03-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS11395 f8a93c01046d063f673524909b77c258 563 SUPERFAMILY SSF53697 11 561 1.47E-194 T 28-03-2018 CFK41_RS11395 f8a93c01046d063f673524909b77c258 563 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 281 294 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS11395 f8a93c01046d063f673524909b77c258 563 PRINTS PR00662 Glucose-6-phosphate isomerase signature 477 495 9.2E-56 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS11395 f8a93c01046d063f673524909b77c258 563 PRINTS PR00662 Glucose-6-phosphate isomerase signature 277 295 9.2E-56 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS11395 f8a93c01046d063f673524909b77c258 563 PRINTS PR00662 Glucose-6-phosphate isomerase signature 354 375 9.2E-56 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS11395 f8a93c01046d063f673524909b77c258 563 PRINTS PR00662 Glucose-6-phosphate isomerase signature 509 522 9.2E-56 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS11395 f8a93c01046d063f673524909b77c258 563 PRINTS PR00662 Glucose-6-phosphate isomerase signature 156 175 9.2E-56 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS11395 f8a93c01046d063f673524909b77c258 563 PRINTS PR00662 Glucose-6-phosphate isomerase signature 495 509 9.2E-56 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS11395 f8a93c01046d063f673524909b77c258 563 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 50 536 39.483 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS11395 f8a93c01046d063f673524909b77c258 563 Gene3D G3DSA:3.40.50.10490 275 524 4.6E-114 T 28-03-2018 CFK41_RS11395 f8a93c01046d063f673524909b77c258 563 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 509 526 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS11395 f8a93c01046d063f673524909b77c258 563 Pfam PF00342 Phosphoglucose isomerase 56 554 2.2E-197 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CFK41_RS06115 8c5e0d053d5c1fdc12e306f7c6b9e808 529 Gene3D G3DSA:3.90.226.10 2 264 8.4E-75 T 28-03-2018 CFK41_RS06115 8c5e0d053d5c1fdc12e306f7c6b9e808 529 Pfam PF01039 Carboxyl transferase domain 35 527 2.4E-189 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CFK41_RS06115 8c5e0d053d5c1fdc12e306f7c6b9e808 529 Gene3D G3DSA:3.90.226.10 265 522 2.3E-72 T 28-03-2018 CFK41_RS06115 8c5e0d053d5c1fdc12e306f7c6b9e808 529 SUPERFAMILY SSF52096 12 263 2.05E-76 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CFK41_RS06115 8c5e0d053d5c1fdc12e306f7c6b9e808 529 SUPERFAMILY SSF52096 232 529 3.66E-86 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CFK41_RS11510 4c17039a83b0bf5d3a5355fcbecb296d 490 SUPERFAMILY SSF53244 333 467 5.76E-33 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CFK41_RS11510 4c17039a83b0bf5d3a5355fcbecb296d 490 Gene3D G3DSA:3.90.190.20 330 482 2.5E-44 T 28-03-2018 CFK41_RS11510 4c17039a83b0bf5d3a5355fcbecb296d 490 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 471 30.712 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CFK41_RS11510 4c17039a83b0bf5d3a5355fcbecb296d 490 Pfam PF01225 Mur ligase family, catalytic domain 32 95 1.6E-8 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CFK41_RS11510 4c17039a83b0bf5d3a5355fcbecb296d 490 SUPERFAMILY SSF53623 107 326 6.93E-47 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CFK41_RS11510 4c17039a83b0bf5d3a5355fcbecb296d 490 SUPERFAMILY SSF63418 2 98 7.59E-19 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CFK41_RS11510 4c17039a83b0bf5d3a5355fcbecb296d 490 Gene3D G3DSA:3.40.1390.10 2 90 6.2E-22 T 28-03-2018 CFK41_RS11510 4c17039a83b0bf5d3a5355fcbecb296d 490 Pfam PF08245 Mur ligase middle domain 112 310 2.1E-38 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CFK41_RS11510 4c17039a83b0bf5d3a5355fcbecb296d 490 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 33 467 1.2E-112 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CFK41_RS11510 4c17039a83b0bf5d3a5355fcbecb296d 490 Pfam PF02875 Mur ligase family, glutamate ligase domain 333 414 3.1E-17 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CFK41_RS11510 4c17039a83b0bf5d3a5355fcbecb296d 490 Gene3D G3DSA:3.40.1190.10 91 326 1.2E-55 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CFK41_RS13795 410e3016de8d87756df5ba5e4f3acef3 346 SUPERFAMILY SSF46955 5 94 2.2E-19 T 28-03-2018 IPR009061 Putative DNA-binding domain CFK41_RS13795 410e3016de8d87756df5ba5e4f3acef3 346 Gene3D G3DSA:1.10.1660.10 1 122 2.3E-16 T 28-03-2018 CFK41_RS13795 410e3016de8d87756df5ba5e4f3acef3 346 SMART SM00331 131 346 1.8E-13 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CFK41_RS13795 410e3016de8d87756df5ba5e4f3acef3 346 SMART SM00332 122 344 4.3E-12 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CFK41_RS13795 410e3016de8d87756df5ba5e4f3acef3 346 Gene3D G3DSA:3.60.40.10 123 345 1.6E-33 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CFK41_RS13795 410e3016de8d87756df5ba5e4f3acef3 346 Pfam PF13411 MerR HTH family regulatory protein 7 71 2.4E-12 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS13795 410e3016de8d87756df5ba5e4f3acef3 346 ProSitePatterns PS00552 MerR-type HTH domain signature. 9 31 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS13795 410e3016de8d87756df5ba5e4f3acef3 346 Pfam PF00481 Protein phosphatase 2C 201 243 1.2E-7 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CFK41_RS13795 410e3016de8d87756df5ba5e4f3acef3 346 SUPERFAMILY SSF81606 126 345 7.06E-44 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CFK41_RS13795 410e3016de8d87756df5ba5e4f3acef3 346 SMART SM00422 6 76 2.1E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS14450 690533c90f0cfdf72b4c1f477eeca272 457 SUPERFAMILY SSF51735 11 144 2.84E-8 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS14450 690533c90f0cfdf72b4c1f477eeca272 457 SMART SM00858 367 432 0.007 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CFK41_RS14450 690533c90f0cfdf72b4c1f477eeca272 457 Gene3D G3DSA:3.40.50.720 10 153 2.2E-12 T 28-03-2018 CFK41_RS08345 b7b1185f136c8818c29643e76f477676 422 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 41 166 2.2E-6 T 28-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 CFK41_RS08345 b7b1185f136c8818c29643e76f477676 422 SUPERFAMILY SSF51445 16 342 1.44E-31 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS08345 b7b1185f136c8818c29643e76f477676 422 Gene3D G3DSA:3.20.20.80 15 334 3.3E-32 T 28-03-2018 CFK41_RS14705 25854d2f72c7ef23792da8255428ff1b 332 SMART SM00354 1 63 5.2E-12 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS14705 25854d2f72c7ef23792da8255428ff1b 332 Pfam PF13377 Periplasmic binding protein-like domain 167 324 2.3E-33 T 28-03-2018 CFK41_RS14705 25854d2f72c7ef23792da8255428ff1b 332 Gene3D G3DSA:3.40.50.2300 172 303 1.6E-42 T 28-03-2018 CFK41_RS14705 25854d2f72c7ef23792da8255428ff1b 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 44 6.0E-12 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS14705 25854d2f72c7ef23792da8255428ff1b 332 Gene3D G3DSA:1.10.260.40 1 54 1.7E-12 T 28-03-2018 CFK41_RS14705 25854d2f72c7ef23792da8255428ff1b 332 SUPERFAMILY SSF53822 54 325 2.36E-63 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS14705 25854d2f72c7ef23792da8255428ff1b 332 Gene3D G3DSA:3.40.50.2300 55 171 1.2E-24 T 28-03-2018 CFK41_RS14705 25854d2f72c7ef23792da8255428ff1b 332 SUPERFAMILY SSF47413 2 50 3.89E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS03720 14c35a7019cd18dbd962ca25fdc1a5f6 168 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 30 150 16.556 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CFK41_RS03720 14c35a7019cd18dbd962ca25fdc1a5f6 168 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 31 145 1.1E-20 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CFK41_RS11135 38024957dd2a4326c111ae1d27b2ad1f 849 Gene3D G3DSA:2.60.40.1730 2 199 3.3E-38 T 28-03-2018 CFK41_RS11135 38024957dd2a4326c111ae1d27b2ad1f 849 SUPERFAMILY SSF63737 5 198 3.01E-41 T 28-03-2018 CFK41_RS11135 38024957dd2a4326c111ae1d27b2ad1f 849 Pfam PF01433 Peptidase family M1 domain 213 447 1.6E-59 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CFK41_RS11135 38024957dd2a4326c111ae1d27b2ad1f 849 Pfam PF11838 ERAP1-like C-terminal domain 530 839 7.4E-52 T 28-03-2018 IPR024571 ERAP1-like C-terminal domain CFK41_RS11135 38024957dd2a4326c111ae1d27b2ad1f 849 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 845 0.0 T 28-03-2018 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 CFK41_RS11135 38024957dd2a4326c111ae1d27b2ad1f 849 Gene3D G3DSA:1.10.390.10 285 451 2.4E-44 T 28-03-2018 CFK41_RS11135 38024957dd2a4326c111ae1d27b2ad1f 849 SUPERFAMILY SSF55486 209 458 4.83E-74 T 28-03-2018 CFK41_RS11135 38024957dd2a4326c111ae1d27b2ad1f 849 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 318 330 4.4E-23 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CFK41_RS11135 38024957dd2a4326c111ae1d27b2ad1f 849 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 265 275 4.4E-23 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CFK41_RS11135 38024957dd2a4326c111ae1d27b2ad1f 849 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 181 196 4.4E-23 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CFK41_RS11135 38024957dd2a4326c111ae1d27b2ad1f 849 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 133 148 4.4E-23 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CFK41_RS11135 38024957dd2a4326c111ae1d27b2ad1f 849 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 299 314 4.4E-23 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CFK41_RS14500 863be6691daa72143ceec905b4a7addd 425 SUPERFAMILY SSF51735 91 223 1.06E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS14500 863be6691daa72143ceec905b4a7addd 425 SUPERFAMILY SSF55347 216 358 5.67E-10 T 28-03-2018 CFK41_RS14500 863be6691daa72143ceec905b4a7addd 425 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 93 210 2.5E-26 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS14500 863be6691daa72143ceec905b4a7addd 425 Gene3D G3DSA:3.40.50.720 90 223 3.9E-38 T 28-03-2018 CFK41_RS14500 863be6691daa72143ceec905b4a7addd 425 Gene3D G3DSA:3.30.360.10 224 424 3.7E-21 T 28-03-2018 CFK41_RS07715 8f2e69904565568cda4b56fb966c9c95 527 Gene3D G3DSA:3.40.190.10 6 194 1.8E-14 T 28-03-2018 CFK41_RS07715 8f2e69904565568cda4b56fb966c9c95 527 SUPERFAMILY SSF53850 22 523 2.68E-66 T 28-03-2018 CFK41_RS07715 8f2e69904565568cda4b56fb966c9c95 527 Gene3D G3DSA:3.40.190.10 195 380 3.0E-22 T 28-03-2018 CFK41_RS07715 8f2e69904565568cda4b56fb966c9c95 527 Pfam PF01547 Bacterial extracellular solute-binding protein 70 372 1.8E-9 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CFK41_RS06865 f4d187c628fe0bd72d46f5a320b12e18 264 ProSitePatterns PS00139 Eukaryotic thiol (cysteine) proteases cysteine active site. 65 76 - T 28-03-2018 IPR000169 Cysteine peptidase, cysteine active site CFK41_RS06865 f4d187c628fe0bd72d46f5a320b12e18 264 SUPERFAMILY SSF54001 63 239 7.06E-19 T 28-03-2018 CFK41_RS06865 f4d187c628fe0bd72d46f5a320b12e18 264 Pfam PF00648 Calpain family cysteine protease 64 227 2.7E-10 T 28-03-2018 IPR001300 Peptidase C2, calpain, catalytic domain GO:0004198|GO:0005622|GO:0006508 Reactome: R-HSA-1474228 CFK41_RS13080 e345ecb8308a1a21894396a7ee02d8b4 183 Pfam PF07155 ECF-type riboflavin transporter, S component 7 170 8.3E-43 T 28-03-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 CFK41_RS13080 e345ecb8308a1a21894396a7ee02d8b4 183 Hamap MF_01572 UPF0397 protein . 3 182 22.702 T 28-03-2018 IPR022914 Protein of unknown function UPF0397 CFK41_RS10930 5e7d796efdbece3493889beac84a73d1 326 Pfam PF13714 Phosphoenolpyruvate phosphomutase 15 258 2.0E-53 T 28-03-2018 CFK41_RS10930 5e7d796efdbece3493889beac84a73d1 326 Gene3D G3DSA:3.20.20.60 8 298 5.0E-88 T 28-03-2018 CFK41_RS10930 5e7d796efdbece3493889beac84a73d1 326 ProSitePatterns PS00161 Isocitrate lyase signature. 124 129 - T 28-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 CFK41_RS10930 5e7d796efdbece3493889beac84a73d1 326 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 12 294 1.5E-116 T 28-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 CFK41_RS10930 5e7d796efdbece3493889beac84a73d1 326 SUPERFAMILY SSF51621 9 293 3.86E-93 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CFK41_RS10930 5e7d796efdbece3493889beac84a73d1 326 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 9 295 45.025 T 28-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 CFK41_RS15670 83f549766e0ed13eb71f46c1c9e17ee2 648 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 26 443 2.8E-107 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CFK41_RS15670 83f549766e0ed13eb71f46c1c9e17ee2 648 Gene3D G3DSA:1.10.3330.10 463 632 2.3E-31 T 28-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 CFK41_RS15670 83f549766e0ed13eb71f46c1c9e17ee2 648 SUPERFAMILY SSF158694 471 631 3.66E-35 T 28-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 CFK41_RS15670 83f549766e0ed13eb71f46c1c9e17ee2 648 Pfam PF00860 Permease family 30 413 7.3E-97 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CFK41_RS15670 83f549766e0ed13eb71f46c1c9e17ee2 648 Pfam PF09349 OHCU decarboxylase 471 626 1.2E-25 T 28-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 CFK41_RS15670 83f549766e0ed13eb71f46c1c9e17ee2 648 TIGRFAM TIGR03173 pbuX: xanthine permease 33 444 2.6E-147 T 28-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 CFK41_RS15670 83f549766e0ed13eb71f46c1c9e17ee2 648 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 360 380 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CFK41_RS08425 45ce9f8c86c0a2fd10e27984faa020ce 152 SUPERFAMILY SSF82649 3 144 1.23E-36 T 28-03-2018 CFK41_RS08425 45ce9f8c86c0a2fd10e27984faa020ce 152 Gene3D G3DSA:3.90.1010.10 5 149 3.6E-38 T 28-03-2018 CFK41_RS08425 45ce9f8c86c0a2fd10e27984faa020ce 152 Pfam PF01592 NifU-like N terminal domain 9 132 1.4E-22 T 28-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 CFK41_RS08425 45ce9f8c86c0a2fd10e27984faa020ce 152 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 6 144 5.0E-39 T 28-03-2018 CFK41_RS11485 bcaee46a82af21ac4f28c981364b09df 505 Pfam PF01225 Mur ligase family, catalytic domain 38 133 4.4E-20 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CFK41_RS11485 bcaee46a82af21ac4f28c981364b09df 505 SUPERFAMILY SSF53244 351 497 2.38E-37 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CFK41_RS11485 bcaee46a82af21ac4f28c981364b09df 505 Gene3D G3DSA:3.40.50.720 31 124 2.2E-14 T 28-03-2018 CFK41_RS11485 bcaee46a82af21ac4f28c981364b09df 505 Pfam PF08245 Mur ligase middle domain 141 329 1.3E-25 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CFK41_RS11485 bcaee46a82af21ac4f28c981364b09df 505 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 38 493 6.7E-121 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CFK41_RS11485 bcaee46a82af21ac4f28c981364b09df 505 Gene3D G3DSA:3.40.1190.10 125 352 1.8E-40 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CFK41_RS11485 bcaee46a82af21ac4f28c981364b09df 505 SUPERFAMILY SSF53623 122 349 1.13E-43 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CFK41_RS11485 bcaee46a82af21ac4f28c981364b09df 505 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 35 500 34.244 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CFK41_RS11485 bcaee46a82af21ac4f28c981364b09df 505 SUPERFAMILY SSF51984 36 124 1.31E-22 T 28-03-2018 CFK41_RS11485 bcaee46a82af21ac4f28c981364b09df 505 Gene3D G3DSA:3.90.190.20 353 500 8.6E-35 T 28-03-2018 CFK41_RS11485 bcaee46a82af21ac4f28c981364b09df 505 Pfam PF02875 Mur ligase family, glutamate ligase domain 353 440 1.7E-18 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CFK41_RS05365 771e1a065d08cbfa4a6be66f6ce3eb77 751 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 84 538 2.2E-145 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CFK41_RS05365 771e1a065d08cbfa4a6be66f6ce3eb77 751 ProSitePatterns PS01303 BCCT family of transporters signature. 355 364 - T 28-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 CFK41_RS05365 771e1a065d08cbfa4a6be66f6ce3eb77 751 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 46 537 1.2E-155 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CFK41_RS09820 022a7489760f717ffd75ec09325549cc 311 Gene3D G3DSA:3.30.420.40 116 311 1.8E-56 T 28-03-2018 CFK41_RS09820 022a7489760f717ffd75ec09325549cc 311 SUPERFAMILY SSF53067 1 311 5.71E-64 T 28-03-2018 CFK41_RS09820 022a7489760f717ffd75ec09325549cc 311 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 4 311 9.2E-86 T 28-03-2018 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 CFK41_RS09820 022a7489760f717ffd75ec09325549cc 311 Pfam PF00480 ROK family 4 311 9.1E-80 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CFK41_RS09820 022a7489760f717ffd75ec09325549cc 311 Gene3D G3DSA:3.30.420.40 1 115 4.4E-33 T 28-03-2018 CFK41_RS15250 c7c0ce6af9027a9b97f4c3870e387fb5 162 SUPERFAMILY SSF55804 19 152 7.32E-25 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CFK41_RS15250 c7c0ce6af9027a9b97f4c3870e387fb5 162 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 21 152 1.9E-21 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CFK41_RS15250 c7c0ce6af9027a9b97f4c3870e387fb5 162 Gene3D G3DSA:3.40.930.10 13 154 7.0E-23 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CFK41_RS04650 147fcf7b2d5a26649cc28e5613a3d69d 61 Gene3D G3DSA:4.10.830.10 1 61 8.5E-23 T 28-03-2018 CFK41_RS04650 147fcf7b2d5a26649cc28e5613a3d69d 61 Pfam PF00253 Ribosomal protein S14p/S29e 11 60 9.3E-25 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS04650 147fcf7b2d5a26649cc28e5613a3d69d 61 SUPERFAMILY SSF57716 4 61 6.91E-22 T 28-03-2018 CFK41_RS04650 147fcf7b2d5a26649cc28e5613a3d69d 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 28-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04650 147fcf7b2d5a26649cc28e5613a3d69d 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 25.822 T 28-03-2018 IPR023053 Ribosomal protein S14, type Z CFK41_RS14060 d5141b6a898a32ec990930d4f850bc17 496 Gene3D G3DSA:1.20.1250.20 278 496 9.2E-24 T 28-03-2018 CFK41_RS14060 d5141b6a898a32ec990930d4f850bc17 496 SUPERFAMILY SSF103473 17 217 6.15E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS14060 d5141b6a898a32ec990930d4f850bc17 496 SUPERFAMILY SSF103473 274 487 6.15E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS14060 d5141b6a898a32ec990930d4f850bc17 496 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 35 445 1.7E-83 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CFK41_RS14060 d5141b6a898a32ec990930d4f850bc17 496 Pfam PF07690 Major Facilitator Superfamily 39 436 7.5E-46 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS14060 d5141b6a898a32ec990930d4f850bc17 496 PRINTS PR01036 Tetracycline resistance protein TetB signature 37 61 2.8E-10 T 28-03-2018 CFK41_RS14060 d5141b6a898a32ec990930d4f850bc17 496 PRINTS PR01036 Tetracycline resistance protein TetB signature 158 182 2.8E-10 T 28-03-2018 CFK41_RS14060 d5141b6a898a32ec990930d4f850bc17 496 PRINTS PR01036 Tetracycline resistance protein TetB signature 427 446 2.8E-10 T 28-03-2018 CFK41_RS14060 d5141b6a898a32ec990930d4f850bc17 496 PRINTS PR01036 Tetracycline resistance protein TetB signature 128 148 2.8E-10 T 28-03-2018 CFK41_RS14060 d5141b6a898a32ec990930d4f850bc17 496 Gene3D G3DSA:1.20.1250.20 31 221 3.4E-26 T 28-03-2018 CFK41_RS12220 c60ded4e9f0bae5c7ba386164d95c133 225 SUPERFAMILY SSF55961 39 164 1.45E-20 T 28-03-2018 CFK41_RS12220 c60ded4e9f0bae5c7ba386164d95c133 225 Gene3D G3DSA:3.30.530.20 16 205 1.1E-24 T 28-03-2018 IPR023393 START-like domain CFK41_RS12220 c60ded4e9f0bae5c7ba386164d95c133 225 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 49 161 4.9E-10 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CFK41_RS01190 288de6b5ae9fb675475cf365951eca85 362 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 144 2.1E-25 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CFK41_RS01190 288de6b5ae9fb675475cf365951eca85 362 SUPERFAMILY SSF50129 3 191 4.4E-45 T 28-03-2018 IPR011032 GroES-like CFK41_RS01190 288de6b5ae9fb675475cf365951eca85 362 Pfam PF00107 Zinc-binding dehydrogenase 192 318 5.0E-22 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CFK41_RS01190 288de6b5ae9fb675475cf365951eca85 362 SUPERFAMILY SSF51735 159 311 1.06E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS01190 288de6b5ae9fb675475cf365951eca85 362 Gene3D G3DSA:3.90.180.10 8 174 4.9E-41 T 28-03-2018 CFK41_RS01190 288de6b5ae9fb675475cf365951eca85 362 Gene3D G3DSA:3.40.50.10730 175 306 3.3E-24 T 28-03-2018 CFK41_RS05865 387157b61ee25a86da193826a2b64af3 840 SMART SM00460 523 593 5.0E-7 T 28-03-2018 IPR002931 Transglutaminase-like CFK41_RS05865 387157b61ee25a86da193826a2b64af3 840 Gene3D G3DSA:3.90.260.10 524 608 5.2E-10 T 28-03-2018 IPR002931 Transglutaminase-like CFK41_RS05865 387157b61ee25a86da193826a2b64af3 840 Pfam PF01841 Transglutaminase-like superfamily 518 591 2.9E-16 T 28-03-2018 IPR002931 Transglutaminase-like CFK41_RS05865 387157b61ee25a86da193826a2b64af3 840 SUPERFAMILY SSF54001 533 598 1.16E-16 T 28-03-2018 CFK41_RS12970 1684df6c6999a37e47410f36e8705e5c 344 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 126 2.0E-31 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CFK41_RS12970 1684df6c6999a37e47410f36e8705e5c 344 Pfam PF00107 Zinc-binding dehydrogenase 176 303 1.7E-24 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CFK41_RS12970 1684df6c6999a37e47410f36e8705e5c 344 Gene3D G3DSA:3.40.50.720 167 287 1.4E-24 T 28-03-2018 CFK41_RS12970 1684df6c6999a37e47410f36e8705e5c 344 SUPERFAMILY SSF50129 11 167 6.24E-46 T 28-03-2018 IPR011032 GroES-like CFK41_RS12970 1684df6c6999a37e47410f36e8705e5c 344 Gene3D G3DSA:3.90.180.10 1 166 3.4E-50 T 28-03-2018 CFK41_RS12970 1684df6c6999a37e47410f36e8705e5c 344 SMART SM00829 10 341 7.4E-6 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CFK41_RS12970 1684df6c6999a37e47410f36e8705e5c 344 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CFK41_RS12970 1684df6c6999a37e47410f36e8705e5c 344 SUPERFAMILY SSF51735 138 308 8.84E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS15135 56180135b202565228a5929202a4cdb2 314 SUPERFAMILY SSF161098 37 314 2.43E-51 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS15135 56180135b202565228a5929202a4cdb2 314 Gene3D G3DSA:1.10.3720.10 30 301 8.8E-34 T 28-03-2018 CFK41_RS15135 56180135b202565228a5929202a4cdb2 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 300 1.5E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01605 6b3c9cc4c4930f13d9e24aceeb22a959 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 297 8.2E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01605 6b3c9cc4c4930f13d9e24aceeb22a959 306 Gene3D G3DSA:1.10.3720.10 19 305 2.1E-55 T 28-03-2018 CFK41_RS01605 6b3c9cc4c4930f13d9e24aceeb22a959 306 SUPERFAMILY SSF161098 63 290 9.81E-57 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS10800 8583c4e480c6d120c1450cce25591ea9 424 Gene3D G3DSA:3.40.190.10 177 351 1.3E-18 T 28-03-2018 CFK41_RS10800 8583c4e480c6d120c1450cce25591ea9 424 Gene3D G3DSA:3.40.190.10 35 176 1.6E-22 T 28-03-2018 CFK41_RS10800 8583c4e480c6d120c1450cce25591ea9 424 Pfam PF13416 Bacterial extracellular solute-binding protein 70 360 6.0E-39 T 28-03-2018 CFK41_RS10800 8583c4e480c6d120c1450cce25591ea9 424 SUPERFAMILY SSF53850 54 419 1.24E-64 T 28-03-2018 CFK41_RS00280 9af878546de171cd4a66c91570650a10 513 SUPERFAMILY SSF103473 243 414 2.09E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS00280 9af878546de171cd4a66c91570650a10 513 SUPERFAMILY SSF103473 461 491 2.09E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS00280 9af878546de171cd4a66c91570650a10 513 SUPERFAMILY SSF103473 3 196 2.09E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS00280 9af878546de171cd4a66c91570650a10 513 Gene3D G3DSA:1.20.1250.20 2 196 4.8E-30 T 28-03-2018 CFK41_RS00280 9af878546de171cd4a66c91570650a10 513 Gene3D G3DSA:1.20.1250.20 254 502 3.7E-27 T 28-03-2018 CFK41_RS00280 9af878546de171cd4a66c91570650a10 513 Pfam PF07690 Major Facilitator Superfamily 16 404 5.9E-51 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS00280 9af878546de171cd4a66c91570650a10 513 ProSitePatterns PS00216 Sugar transport proteins signature 1. 63 80 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CFK41_RS04295 17ac4fb51d26af15ca4b168d5cebcd34 425 Gene3D G3DSA:3.40.800.20 20 374 1.2E-84 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CFK41_RS04295 17ac4fb51d26af15ca4b168d5cebcd34 425 PRINTS PR01270 Histone deacetylase superfamily signature 155 178 2.2E-18 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CFK41_RS04295 17ac4fb51d26af15ca4b168d5cebcd34 425 PRINTS PR01270 Histone deacetylase superfamily signature 188 203 2.2E-18 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CFK41_RS04295 17ac4fb51d26af15ca4b168d5cebcd34 425 PRINTS PR01270 Histone deacetylase superfamily signature 274 284 2.2E-18 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CFK41_RS04295 17ac4fb51d26af15ca4b168d5cebcd34 425 SUPERFAMILY SSF52768 20 360 2.16E-93 T 28-03-2018 CFK41_RS04295 17ac4fb51d26af15ca4b168d5cebcd34 425 Pfam PF00850 Histone deacetylase domain 40 343 4.1E-68 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CFK41_RS16990 b1c3fd52ad7dd9ad3c144032a552fe9f 230 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 68 2.4E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS16990 b1c3fd52ad7dd9ad3c144032a552fe9f 230 SUPERFAMILY SSF48008 91 223 1.36E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS16990 b1c3fd52ad7dd9ad3c144032a552fe9f 230 Pfam PF07729 FCD domain 94 215 3.5E-23 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS16990 b1c3fd52ad7dd9ad3c144032a552fe9f 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 2.8E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS16990 b1c3fd52ad7dd9ad3c144032a552fe9f 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 2.8E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS16990 b1c3fd52ad7dd9ad3c144032a552fe9f 230 Gene3D G3DSA:1.10.10.10 2 67 1.4E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS16990 b1c3fd52ad7dd9ad3c144032a552fe9f 230 SMART SM00895 94 216 3.9E-19 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS16990 b1c3fd52ad7dd9ad3c144032a552fe9f 230 SUPERFAMILY SSF46785 6 82 8.89E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS16990 b1c3fd52ad7dd9ad3c144032a552fe9f 230 Gene3D G3DSA:1.20.120.530 68 227 1.3E-28 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS16990 b1c3fd52ad7dd9ad3c144032a552fe9f 230 SMART SM00345 9 68 9.3E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS06675 e818cd292ebf31937f254f8457eb5507 298 Gene3D G3DSA:3.40.50.720 1 179 5.4E-22 T 28-03-2018 CFK41_RS06675 e818cd292ebf31937f254f8457eb5507 298 Pfam PF13460 NAD(P)H-binding 7 189 9.1E-19 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS06675 e818cd292ebf31937f254f8457eb5507 298 SUPERFAMILY SSF51735 2 288 2.68E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS06675 e818cd292ebf31937f254f8457eb5507 298 Gene3D G3DSA:3.90.25.10 180 292 5.6E-9 T 28-03-2018 CFK41_RS11835 3c1d455b796c77f578306bcf704d86d4 250 Hamap MF_01220_B Uridylate kinase [pyrH]. 16 249 41.2 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CFK41_RS11835 3c1d455b796c77f578306bcf704d86d4 250 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 19 249 7.8E-86 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CFK41_RS11835 3c1d455b796c77f578306bcf704d86d4 250 Gene3D G3DSA:3.40.1160.10 11 250 9.4E-43 T 28-03-2018 CFK41_RS11835 3c1d455b796c77f578306bcf704d86d4 250 SUPERFAMILY SSF53633 19 249 5.5E-68 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CFK41_RS11835 3c1d455b796c77f578306bcf704d86d4 250 Pfam PF00696 Amino acid kinase family 21 227 2.8E-27 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CFK41_RS11835 3c1d455b796c77f578306bcf704d86d4 250 PIRSF PIRSF005650 14 250 4.9E-84 T 28-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 CFK41_RS03505 33807f43d515abf6e5339dcfb3051bf8 401 Gene3D G3DSA:3.40.50.300 183 396 1.1E-11 T 28-03-2018 CFK41_RS03505 33807f43d515abf6e5339dcfb3051bf8 401 SUPERFAMILY SSF52540 184 371 2.42E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS05125 1de36d351a003b250612dad41f07876c 173 Pfam PF13671 AAA domain 5 136 2.8E-14 T 28-03-2018 CFK41_RS05125 1de36d351a003b250612dad41f07876c 173 SUPERFAMILY SSF52540 3 171 5.82E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS05125 1de36d351a003b250612dad41f07876c 173 Gene3D G3DSA:3.40.50.300 2 173 2.0E-19 T 28-03-2018 CFK41_RS16530 6a4fae550c06311321891d09c0dbbf49 452 SMART SM00924 35 138 1.4E-24 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CFK41_RS16530 6a4fae550c06311321891d09c0dbbf49 452 Pfam PF00571 CBS domain 139 196 3.7E-5 T 28-03-2018 IPR000644 CBS domain CFK41_RS16530 6a4fae550c06311321891d09c0dbbf49 452 Pfam PF00571 CBS domain 210 253 0.001 T 28-03-2018 IPR000644 CBS domain CFK41_RS16530 6a4fae550c06311321891d09c0dbbf49 452 TIGRFAM TIGR00400 mgtE: magnesium transporter 34 451 1.2E-106 T 28-03-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 CFK41_RS16530 6a4fae550c06311321891d09c0dbbf49 452 SMART SM00116 145 198 0.53 T 28-03-2018 IPR000644 CBS domain CFK41_RS16530 6a4fae550c06311321891d09c0dbbf49 452 SMART SM00116 208 256 0.0036 T 28-03-2018 IPR000644 CBS domain CFK41_RS16530 6a4fae550c06311321891d09c0dbbf49 452 Gene3D G3DSA:3.10.580.10 127 271 1.4E-15 T 28-03-2018 CFK41_RS16530 6a4fae550c06311321891d09c0dbbf49 452 SUPERFAMILY SSF54631 138 274 3.28E-25 T 28-03-2018 CFK41_RS16530 6a4fae550c06311321891d09c0dbbf49 452 Gene3D G3DSA:1.25.60.10 2 126 3.7E-14 T 28-03-2018 CFK41_RS16530 6a4fae550c06311321891d09c0dbbf49 452 SUPERFAMILY SSF161093 280 450 3.79E-47 T 28-03-2018 CFK41_RS16530 6a4fae550c06311321891d09c0dbbf49 452 SUPERFAMILY SSF158791 23 134 4.05E-21 T 28-03-2018 CFK41_RS16530 6a4fae550c06311321891d09c0dbbf49 452 Gene3D G3DSA:1.10.357.20 279 451 1.5E-38 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 CFK41_RS16530 6a4fae550c06311321891d09c0dbbf49 452 Pfam PF01769 Divalent cation transporter 323 443 7.6E-28 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 CFK41_RS16530 6a4fae550c06311321891d09c0dbbf49 452 Pfam PF03448 MgtE intracellular N domain 36 135 4.3E-21 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CFK41_RS01130 edb82c1fab7b501f4a0a8c228d9b5983 319 Pfam PF04198 Putative sugar-binding domain 65 317 2.9E-60 T 28-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 CFK41_RS01130 edb82c1fab7b501f4a0a8c228d9b5983 319 SUPERFAMILY SSF100950 64 316 1.09E-61 T 28-03-2018 CFK41_RS01130 edb82c1fab7b501f4a0a8c228d9b5983 319 Gene3D G3DSA:3.40.50.1360 57 319 6.2E-42 T 28-03-2018 CFK41_RS01130 edb82c1fab7b501f4a0a8c228d9b5983 319 Pfam PF13384 Homeodomain-like domain 13 50 1.0E-5 T 28-03-2018 CFK41_RS01130 edb82c1fab7b501f4a0a8c228d9b5983 319 Gene3D G3DSA:1.10.10.60 1 54 2.0E-14 T 28-03-2018 CFK41_RS02775 9c88e56cccf003f705bde96f52a21715 253 Gene3D G3DSA:3.40.50.150 15 252 2.9E-25 T 28-03-2018 CFK41_RS02775 9c88e56cccf003f705bde96f52a21715 253 Pfam PF13649 Methyltransferase domain 53 145 1.4E-12 T 28-03-2018 CFK41_RS02775 9c88e56cccf003f705bde96f52a21715 253 SUPERFAMILY SSF53335 25 242 5.31E-30 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS14580 606792ebdabb8967a9d2b9d36531f474 218 SUPERFAMILY SSF51569 26 209 4.76E-45 T 28-03-2018 CFK41_RS14580 606792ebdabb8967a9d2b9d36531f474 218 Gene3D G3DSA:3.20.20.70 23 218 1.1E-24 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS14580 606792ebdabb8967a9d2b9d36531f474 218 Pfam PF01081 KDPG and KHG aldolase 29 206 1.5E-33 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CFK41_RS11790 38c9859d97b5c43346937bd0c7de585b 280 Pfam PF00583 Acetyltransferase (GNAT) family 208 269 1.7E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS11790 38c9859d97b5c43346937bd0c7de585b 280 Gene3D G3DSA:3.40.630.30 148 280 8.6E-21 T 28-03-2018 CFK41_RS11790 38c9859d97b5c43346937bd0c7de585b 280 Pfam PF13312 Domain of unknown function (DUF4081) 59 137 5.2E-18 T 28-03-2018 IPR025289 Domain of unknown function DUF4081 CFK41_RS11790 38c9859d97b5c43346937bd0c7de585b 280 SUPERFAMILY SSF55729 141 275 7.27E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS01435 193b01d9508278c2fb7577e9da94b731 218 SUPERFAMILY SSF49899 4 217 2.53E-69 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CFK41_RS01435 193b01d9508278c2fb7577e9da94b731 218 ProDom PD113327 YESU 3D-STRUCTURE 4 218 6.0E-51 T 28-03-2018 IPR015305 Protein of unknown function DUF1961 CFK41_RS01435 193b01d9508278c2fb7577e9da94b731 218 Pfam PF09224 Domain of unknown function (DUF1961) 4 215 1.1E-78 T 28-03-2018 IPR015305 Protein of unknown function DUF1961 CFK41_RS01435 193b01d9508278c2fb7577e9da94b731 218 Gene3D G3DSA:2.60.120.200 1 218 2.7E-38 T 28-03-2018 CFK41_RS10850 adcc87884baa3030a548519ec3358dd6 146 SUPERFAMILY SSF46955 15 103 3.07E-19 T 28-03-2018 IPR009061 Putative DNA-binding domain CFK41_RS10850 adcc87884baa3030a548519ec3358dd6 146 Pfam PF13411 MerR HTH family regulatory protein 16 81 2.9E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS10850 adcc87884baa3030a548519ec3358dd6 146 Gene3D G3DSA:1.10.1660.10 2 124 9.9E-24 T 28-03-2018 CFK41_RS10850 adcc87884baa3030a548519ec3358dd6 146 SMART SM00422 14 83 2.7E-24 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS11990 b484393b519ee66481542c3bf9e7e786 520 Gene3D G3DSA:1.10.287.850 1 93 3.7E-9 T 28-03-2018 CFK41_RS11990 b484393b519ee66481542c3bf9e7e786 520 Gene3D G3DSA:3.40.50.1820 249 419 1.9E-7 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS11990 b484393b519ee66481542c3bf9e7e786 520 SUPERFAMILY SSF53474 303 412 4.19E-8 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS11990 b484393b519ee66481542c3bf9e7e786 520 SUPERFAMILY SSF140453 7 83 2.88E-6 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CFK41_RS11990 b484393b519ee66481542c3bf9e7e786 520 Pfam PF06013 Proteins of 100 residues with WXG 7 81 2.3E-6 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CFK41_RS01770 dbf02233cb9fb88b04addf14d831c8d8 295 Pfam PF05448 Acetyl xylan esterase (AXE1) 145 200 5.5E-9 T 28-03-2018 IPR008391 Acetyl xylan esterase CFK41_RS01770 dbf02233cb9fb88b04addf14d831c8d8 295 Gene3D G3DSA:3.40.50.1820 30 294 1.2E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS01770 dbf02233cb9fb88b04addf14d831c8d8 295 SUPERFAMILY SSF53474 22 291 4.23E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS10260 3d2303eb5e40ed247e00b43bab3d43d3 295 SMART SM00650 43 220 4.1E-63 T 28-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CFK41_RS10260 3d2303eb5e40ed247e00b43bab3d43d3 295 Pfam PF00398 Ribosomal RNA adenine dimethylase 31 252 7.5E-41 T 28-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CFK41_RS10260 3d2303eb5e40ed247e00b43bab3d43d3 295 SUPERFAMILY SSF53335 26 290 1.78E-63 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS10260 3d2303eb5e40ed247e00b43bab3d43d3 295 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 27 292 46.27 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CFK41_RS10260 3d2303eb5e40ed247e00b43bab3d43d3 295 Gene3D G3DSA:1.10.8.100 234 292 3.3E-18 T 28-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 CFK41_RS10260 3d2303eb5e40ed247e00b43bab3d43d3 295 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 27 289 1.1E-66 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CFK41_RS10260 3d2303eb5e40ed247e00b43bab3d43d3 295 Gene3D G3DSA:3.40.50.150 16 233 1.7E-47 T 28-03-2018 CFK41_RS10260 3d2303eb5e40ed247e00b43bab3d43d3 295 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 59 86 - T 28-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CFK41_RS12270 c271ba5a0c8097e27362f1b4bbe97235 422 SUPERFAMILY SSF55874 211 376 7.07E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS12270 c271ba5a0c8097e27362f1b4bbe97235 422 Pfam PF00512 His Kinase A (phospho-acceptor) domain 156 220 6.5E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CFK41_RS12270 c271ba5a0c8097e27362f1b4bbe97235 422 SMART SM00388 155 221 2.0E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CFK41_RS12270 c271ba5a0c8097e27362f1b4bbe97235 422 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 270 376 5.8E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS12270 c271ba5a0c8097e27362f1b4bbe97235 422 SMART SM00387 266 378 3.1E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS12270 c271ba5a0c8097e27362f1b4bbe97235 422 Gene3D G3DSA:1.10.287.130 146 217 5.5E-15 T 28-03-2018 CFK41_RS12270 c271ba5a0c8097e27362f1b4bbe97235 422 Gene3D G3DSA:3.30.565.10 225 385 2.8E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS12270 c271ba5a0c8097e27362f1b4bbe97235 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 303 317 2.3E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS12270 c271ba5a0c8097e27362f1b4bbe97235 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 338 356 2.3E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS12270 c271ba5a0c8097e27362f1b4bbe97235 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 321 331 2.3E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS12270 c271ba5a0c8097e27362f1b4bbe97235 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 375 2.3E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS12270 c271ba5a0c8097e27362f1b4bbe97235 422 SUPERFAMILY SSF47384 141 219 3.92E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CFK41_RS03010 3bbc92fc1038f060134eb8c9b08983c2 447 Pfam PF13672 Protein phosphatase 2C 18 198 2.4E-13 T 28-03-2018 CFK41_RS03010 3bbc92fc1038f060134eb8c9b08983c2 447 SUPERFAMILY SSF81606 5 237 1.57E-66 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CFK41_RS03010 3bbc92fc1038f060134eb8c9b08983c2 447 SMART SM00331 11 238 3.6E-34 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CFK41_RS03010 3bbc92fc1038f060134eb8c9b08983c2 447 Gene3D G3DSA:3.60.40.10 5 238 4.4E-44 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CFK41_RS03010 3bbc92fc1038f060134eb8c9b08983c2 447 SMART SM00332 2 236 4.0E-28 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CFK41_RS05445 af559faca2cea208b5051dc08365ddfd 271 Pfam PF00005 ABC transporter 24 170 1.0E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS05445 af559faca2cea208b5051dc08365ddfd 271 Gene3D G3DSA:3.40.50.300 2 239 1.7E-58 T 28-03-2018 CFK41_RS05445 af559faca2cea208b5051dc08365ddfd 271 SUPERFAMILY SSF52540 6 233 7.58E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS05445 af559faca2cea208b5051dc08365ddfd 271 SMART SM00382 31 220 6.5E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS05445 af559faca2cea208b5051dc08365ddfd 271 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS15620 0c3768b0fbe23cbaa7489d72610796f9 252 SUPERFAMILY SSF46894 147 243 9.16E-24 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CFK41_RS15620 0c3768b0fbe23cbaa7489d72610796f9 252 SMART SM00862 168 242 1.2E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CFK41_RS15620 0c3768b0fbe23cbaa7489d72610796f9 252 Gene3D G3DSA:1.10.10.10 145 249 1.3E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS15620 0c3768b0fbe23cbaa7489d72610796f9 252 Pfam PF00486 Transcriptional regulatory protein, C terminal 168 242 1.1E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CFK41_RS10310 114bfa6f5c59ed00fc61787cf662af8e 236 Gene3D G3DSA:3.40.50.1820 2 230 1.4E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS10310 114bfa6f5c59ed00fc61787cf662af8e 236 SUPERFAMILY SSF53474 5 228 8.95E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS10310 114bfa6f5c59ed00fc61787cf662af8e 236 PRINTS PR00111 Alpha/beta hydrolase fold signature 70 83 3.6E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CFK41_RS10310 114bfa6f5c59ed00fc61787cf662af8e 236 PRINTS PR00111 Alpha/beta hydrolase fold signature 29 44 3.6E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CFK41_RS10310 114bfa6f5c59ed00fc61787cf662af8e 236 Pfam PF12697 Alpha/beta hydrolase family 5 224 5.5E-19 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CFK41_RS10475 242d4cda9476858775291a8f73047ddf 529 PIRSF PIRSF026631 17 502 1.8E-63 T 28-03-2018 IPR014529 Uncharacterised conserved protein UCP026631 CFK41_RS10475 242d4cda9476858775291a8f73047ddf 529 Pfam PF03703 Bacterial PH domain 426 475 1.9E-9 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CFK41_RS10475 242d4cda9476858775291a8f73047ddf 529 Pfam PF03703 Bacterial PH domain 83 160 1.0E-14 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CFK41_RS10475 242d4cda9476858775291a8f73047ddf 529 Pfam PF03703 Bacterial PH domain 297 373 8.9E-7 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CFK41_RS10475 242d4cda9476858775291a8f73047ddf 529 SUPERFAMILY SSF90123 219 289 7.85E-6 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS10475 242d4cda9476858775291a8f73047ddf 529 SUPERFAMILY SSF90123 30 111 7.85E-6 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS13835 8bf24ecbf97490459db2e4af8db06557 373 SUPERFAMILY SSF117892 64 197 3.27E-26 T 28-03-2018 IPR001107 Band 7 domain CFK41_RS13835 8bf24ecbf97490459db2e4af8db06557 373 PRINTS PR00721 Stomatin signature 186 207 7.6E-5 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CFK41_RS13835 8bf24ecbf97490459db2e4af8db06557 373 PRINTS PR00721 Stomatin signature 86 107 7.6E-5 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CFK41_RS13835 8bf24ecbf97490459db2e4af8db06557 373 PRINTS PR00721 Stomatin signature 39 61 7.6E-5 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CFK41_RS13835 8bf24ecbf97490459db2e4af8db06557 373 PRINTS PR00721 Stomatin signature 143 166 7.6E-5 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CFK41_RS13835 8bf24ecbf97490459db2e4af8db06557 373 SMART SM00244 32 191 1.7E-29 T 28-03-2018 IPR001107 Band 7 domain CFK41_RS13835 8bf24ecbf97490459db2e4af8db06557 373 Pfam PF01145 SPFH domain / Band 7 family 36 207 8.9E-30 T 28-03-2018 IPR001107 Band 7 domain CFK41_RS08580 f379333de074cdd8651d9a8b71c3d743 302 SUPERFAMILY SSF51735 105 276 2.17E-18 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS08580 f379333de074cdd8651d9a8b71c3d743 302 Gene3D G3DSA:3.40.50.10860 1 114 6.8E-34 T 28-03-2018 CFK41_RS08580 f379333de074cdd8651d9a8b71c3d743 302 Gene3D G3DSA:3.40.50.720 115 280 9.9E-20 T 28-03-2018 CFK41_RS08580 f379333de074cdd8651d9a8b71c3d743 302 SUPERFAMILY SSF53223 4 103 1.27E-20 T 28-03-2018 CFK41_RS08580 f379333de074cdd8651d9a8b71c3d743 302 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 8 91 3.7E-17 T 28-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CFK41_RS17575 cc2c0fa5394af6c23bae2b7a546975bb 78 Gene3D G3DSA:4.10.640.10 2 78 1.5E-28 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS17575 cc2c0fa5394af6c23bae2b7a546975bb 78 SUPERFAMILY SSF46911 6 75 4.19E-25 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS17575 cc2c0fa5394af6c23bae2b7a546975bb 78 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 3 76 19.949 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS17575 cc2c0fa5394af6c23bae2b7a546975bb 78 TIGRFAM TIGR00165 S18: ribosomal protein bS18 9 74 2.0E-22 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS17575 cc2c0fa5394af6c23bae2b7a546975bb 78 Pfam PF01084 Ribosomal protein S18 22 71 1.7E-22 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS17575 cc2c0fa5394af6c23bae2b7a546975bb 78 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 24 74 2.0E-20 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS17575 cc2c0fa5394af6c23bae2b7a546975bb 78 PRINTS PR00974 Ribosomal protein S18 family signature 63 73 1.4E-17 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS17575 cc2c0fa5394af6c23bae2b7a546975bb 78 PRINTS PR00974 Ribosomal protein S18 family signature 31 41 1.4E-17 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS17575 cc2c0fa5394af6c23bae2b7a546975bb 78 PRINTS PR00974 Ribosomal protein S18 family signature 49 63 1.4E-17 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS17575 cc2c0fa5394af6c23bae2b7a546975bb 78 PRINTS PR00974 Ribosomal protein S18 family signature 41 48 1.4E-17 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS16230 46c3802312f86033eeb198374d895c17 335 Gene3D G3DSA:3.40.50.720 2 138 1.8E-43 T 28-03-2018 CFK41_RS16230 46c3802312f86033eeb198374d895c17 335 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 7 125 2.2E-27 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS16230 46c3802312f86033eeb198374d895c17 335 SUPERFAMILY SSF55347 132 305 5.89E-30 T 28-03-2018 CFK41_RS16230 46c3802312f86033eeb198374d895c17 335 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 138 228 3.8E-4 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CFK41_RS16230 46c3802312f86033eeb198374d895c17 335 Gene3D G3DSA:3.30.360.10 139 334 2.1E-41 T 28-03-2018 CFK41_RS16230 46c3802312f86033eeb198374d895c17 335 SUPERFAMILY SSF51735 6 155 4.04E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS00325 297fb0056e863fd75cebd056ceda8ca4 330 SUPERFAMILY SSF56112 38 277 8.68E-30 T 28-03-2018 IPR011009 Protein kinase-like domain CFK41_RS00325 297fb0056e863fd75cebd056ceda8ca4 330 PIRSF PIRSF000707 21 256 7.5E-16 T 28-03-2018 IPR016259 Hygromycin-B kinase KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CFK41_RS00325 297fb0056e863fd75cebd056ceda8ca4 330 PIRSF PIRSF000707 301 330 140.0 T 28-03-2018 IPR016259 Hygromycin-B kinase KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CFK41_RS00325 297fb0056e863fd75cebd056ceda8ca4 330 Gene3D G3DSA:3.30.200.20 23 114 5.3E-4 T 28-03-2018 CFK41_RS00325 297fb0056e863fd75cebd056ceda8ca4 330 Pfam PF01636 Phosphotransferase enzyme family 50 246 4.4E-28 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CFK41_RS00325 297fb0056e863fd75cebd056ceda8ca4 330 Gene3D G3DSA:3.90.1200.10 121 312 2.9E-19 T 28-03-2018 CFK41_RS13295 e6e3c9204996efa8e055e1b36823f7ec 245 Pfam PF00005 ABC transporter 11 169 2.0E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS13295 e6e3c9204996efa8e055e1b36823f7ec 245 SMART SM00382 20 218 5.2E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS13295 e6e3c9204996efa8e055e1b36823f7ec 245 SUPERFAMILY SSF52540 3 240 1.03E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS13295 e6e3c9204996efa8e055e1b36823f7ec 245 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS13295 e6e3c9204996efa8e055e1b36823f7ec 245 PIRSF PIRSF039085 1 245 2.1E-100 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CFK41_RS13295 e6e3c9204996efa8e055e1b36823f7ec 245 Gene3D G3DSA:3.40.50.300 1 244 2.9E-67 T 28-03-2018 CFK41_RS05235 82342fe7b97575174b960a71ef75c66b 141 Pfam PF12120 Rifampin ADP-ribosyl transferase 12 114 4.7E-42 T 28-03-2018 IPR021975 DNA/RNA tunnel of bacterial DNA dependent RNA polymerase CFK41_RS07805 dc7edcf54ca353fb7e21293dd11537e0 266 PIRSF PIRSF030013 7 244 8.0E-103 T 28-03-2018 IPR009381 Trehalose catabolism protein, ThuA, prokaryote CFK41_RS07805 dc7edcf54ca353fb7e21293dd11537e0 266 Gene3D G3DSA:3.40.50.880 1 246 3.0E-51 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS07805 dc7edcf54ca353fb7e21293dd11537e0 266 Pfam PF06283 Trehalose utilisation 9 227 5.7E-31 T 28-03-2018 IPR029010 ThuA-like domain CFK41_RS07805 dc7edcf54ca353fb7e21293dd11537e0 266 SUPERFAMILY SSF52317 7 229 2.75E-59 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS17525 1e0d9a7ead3dde8082a1b74bfaaa1673 353 Gene3D G3DSA:3.40.50.720 181 353 1.5E-27 T 28-03-2018 CFK41_RS17525 1e0d9a7ead3dde8082a1b74bfaaa1673 353 Gene3D G3DSA:3.50.50.60 28 180 3.4E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS17525 1e0d9a7ead3dde8082a1b74bfaaa1673 353 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 34 334 3.0E-118 T 28-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 CFK41_RS17525 1e0d9a7ead3dde8082a1b74bfaaa1673 353 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 164 184 - T 28-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 CFK41_RS17525 1e0d9a7ead3dde8082a1b74bfaaa1673 353 SUPERFAMILY SSF51905 28 334 2.19E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS17525 1e0d9a7ead3dde8082a1b74bfaaa1673 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 262 283 9.7E-76 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CFK41_RS17525 1e0d9a7ead3dde8082a1b74bfaaa1673 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 135 143 9.7E-76 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CFK41_RS17525 1e0d9a7ead3dde8082a1b74bfaaa1673 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 224 240 9.7E-76 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CFK41_RS17525 1e0d9a7ead3dde8082a1b74bfaaa1673 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 157 169 9.7E-76 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CFK41_RS17525 1e0d9a7ead3dde8082a1b74bfaaa1673 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 172 196 9.7E-76 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CFK41_RS17525 1e0d9a7ead3dde8082a1b74bfaaa1673 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 297 315 9.7E-76 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CFK41_RS17525 1e0d9a7ead3dde8082a1b74bfaaa1673 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 89 99 9.7E-76 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CFK41_RS17525 1e0d9a7ead3dde8082a1b74bfaaa1673 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 34 56 9.7E-76 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CFK41_RS17525 1e0d9a7ead3dde8082a1b74bfaaa1673 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 68 83 9.7E-76 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CFK41_RS17525 1e0d9a7ead3dde8082a1b74bfaaa1673 353 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 134 152 4.9E-38 T 28-03-2018 CFK41_RS17525 1e0d9a7ead3dde8082a1b74bfaaa1673 353 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 287 309 4.9E-38 T 28-03-2018 CFK41_RS17525 1e0d9a7ead3dde8082a1b74bfaaa1673 353 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 176 194 4.9E-38 T 28-03-2018 CFK41_RS17525 1e0d9a7ead3dde8082a1b74bfaaa1673 353 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 35 54 4.9E-38 T 28-03-2018 CFK41_RS17525 1e0d9a7ead3dde8082a1b74bfaaa1673 353 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 276 4.9E-38 T 28-03-2018 CFK41_RS17525 1e0d9a7ead3dde8082a1b74bfaaa1673 353 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 34 323 4.2E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS02140 5f193f4c1ca32a8bb83d0240d1b6ea6a 153 Gene3D G3DSA:3.10.180.10 13 151 1.8E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS02140 5f193f4c1ca32a8bb83d0240d1b6ea6a 153 SUPERFAMILY SSF54593 17 142 8.88E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS01535 8e2eae475c0d8b9c59b9f70c94ec89ea 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 297 5.4E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01535 8e2eae475c0d8b9c59b9f70c94ec89ea 304 Gene3D G3DSA:1.10.3720.10 24 299 2.3E-46 T 28-03-2018 CFK41_RS01535 8e2eae475c0d8b9c59b9f70c94ec89ea 304 SUPERFAMILY SSF161098 65 292 7.46E-62 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS09180 78d1160d3413ffa4231a9e91655e317f 332 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 23 108 7.5E-19 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CFK41_RS09180 78d1160d3413ffa4231a9e91655e317f 332 SUPERFAMILY SSF47823 19 113 2.35E-14 T 28-03-2018 IPR010998 Integrase, Lambda-type, N-terminal CFK41_RS09180 78d1160d3413ffa4231a9e91655e317f 332 Gene3D G3DSA:1.10.443.10 133 322 2.6E-46 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CFK41_RS09180 78d1160d3413ffa4231a9e91655e317f 332 Gene3D G3DSA:1.10.150.130 19 131 2.4E-18 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CFK41_RS09180 78d1160d3413ffa4231a9e91655e317f 332 SUPERFAMILY SSF56349 127 325 5.3E-50 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CFK41_RS09180 78d1160d3413ffa4231a9e91655e317f 332 Pfam PF00589 Phage integrase family 137 313 8.5E-42 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CFK41_RS09180 78d1160d3413ffa4231a9e91655e317f 332 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 21 328 51.203 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD CFK41_RS01160 12f7122b128eea9d05d5fe1c1e126767 326 SUPERFAMILY SSF161098 88 312 1.19E-54 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01160 12f7122b128eea9d05d5fe1c1e126767 326 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 317 2.9E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01160 12f7122b128eea9d05d5fe1c1e126767 326 Gene3D G3DSA:1.10.3720.10 45 324 1.5E-41 T 28-03-2018 CFK41_RS07285 20178b525f628af7d8a8b4f244dc3204 323 Gene3D G3DSA:2.40.10.10 231 323 2.8E-29 T 28-03-2018 CFK41_RS07285 20178b525f628af7d8a8b4f244dc3204 323 Gene3D G3DSA:2.40.10.10 119 198 5.3E-6 T 28-03-2018 CFK41_RS07285 20178b525f628af7d8a8b4f244dc3204 323 SUPERFAMILY SSF50494 110 303 3.03E-21 T 28-03-2018 IPR009003 Peptidase S1, PA clan CFK41_RS07285 20178b525f628af7d8a8b4f244dc3204 323 Gene3D G3DSA:2.40.350.10 199 230 0.0023 T 28-03-2018 IPR023159 SO1590-like domain CFK41_RS10735 36586221ef04968a3b04179695b28b62 403 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 210 391 5.7E-5 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CFK41_RS10735 36586221ef04968a3b04179695b28b62 403 SUPERFAMILY SSF51726 5 91 1.7E-48 T 28-03-2018 CFK41_RS10735 36586221ef04968a3b04179695b28b62 403 SUPERFAMILY SSF51726 125 398 1.7E-48 T 28-03-2018 CFK41_RS10735 36586221ef04968a3b04179695b28b62 403 Gene3D G3DSA:3.20.20.210 1 403 3.3E-92 T 28-03-2018 CFK41_RS01615 3a4707f139a33ca0bf62c42c61893752 420 SUPERFAMILY SSF53850 30 418 9.83E-63 T 28-03-2018 CFK41_RS01615 3a4707f139a33ca0bf62c42c61893752 420 Pfam PF13416 Bacterial extracellular solute-binding protein 63 356 3.5E-31 T 28-03-2018 CFK41_RS01615 3a4707f139a33ca0bf62c42c61893752 420 Gene3D G3DSA:3.40.190.10 229 376 3.0E-6 T 28-03-2018 CFK41_RS01615 3a4707f139a33ca0bf62c42c61893752 420 Gene3D G3DSA:3.40.190.10 47 223 3.1E-36 T 28-03-2018 CFK41_RS10520 fbcc6701aa5d1e573f679ea66172c19e 469 Gene3D G3DSA:3.40.710.10 85 468 2.0E-32 T 28-03-2018 CFK41_RS10520 fbcc6701aa5d1e573f679ea66172c19e 469 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 94 231 2.8E-15 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CFK41_RS10520 fbcc6701aa5d1e573f679ea66172c19e 469 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 239 464 9.5E-42 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CFK41_RS10520 fbcc6701aa5d1e573f679ea66172c19e 469 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 355 369 6.6E-11 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CFK41_RS10520 fbcc6701aa5d1e573f679ea66172c19e 469 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 122 141 6.6E-11 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CFK41_RS10520 fbcc6701aa5d1e573f679ea66172c19e 469 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 340 354 6.6E-11 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CFK41_RS10520 fbcc6701aa5d1e573f679ea66172c19e 469 SUPERFAMILY SSF56601 90 467 5.27E-47 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CFK41_RS12360 bd3c08530d1d3b948ca8b4061ddf68f5 313 Pfam PF00877 NlpC/P60 family 217 299 9.8E-22 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CFK41_RS12360 bd3c08530d1d3b948ca8b4061ddf68f5 313 SUPERFAMILY SSF54001 198 308 2.6E-36 T 28-03-2018 CFK41_RS12360 bd3c08530d1d3b948ca8b4061ddf68f5 313 Gene3D G3DSA:3.90.1720.10 193 308 2.3E-31 T 28-03-2018 CFK41_RS13010 ba1aa5c06a2b85aa9ba2a59c300b5557 115 SMART SM00418 19 97 1.1E-20 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS13010 ba1aa5c06a2b85aa9ba2a59c300b5557 115 SUPERFAMILY SSF46785 6 99 1.86E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS13010 ba1aa5c06a2b85aa9ba2a59c300b5557 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 53 68 2.1E-10 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS13010 ba1aa5c06a2b85aa9ba2a59c300b5557 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 21 36 2.1E-10 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS13010 ba1aa5c06a2b85aa9ba2a59c300b5557 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 68 83 2.1E-10 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS13010 ba1aa5c06a2b85aa9ba2a59c300b5557 115 Pfam PF01022 Bacterial regulatory protein, arsR family 26 71 1.0E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS13010 ba1aa5c06a2b85aa9ba2a59c300b5557 115 Gene3D G3DSA:1.10.10.10 3 104 2.2E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS02690 f193c3976c9d08eb95f3892dc2665747 425 Gene3D G3DSA:1.20.1250.20 234 422 6.6E-13 T 28-03-2018 CFK41_RS02690 f193c3976c9d08eb95f3892dc2665747 425 SUPERFAMILY SSF103473 29 415 8.89E-33 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS02690 f193c3976c9d08eb95f3892dc2665747 425 Gene3D G3DSA:1.20.1250.20 19 219 1.9E-13 T 28-03-2018 CFK41_RS02690 f193c3976c9d08eb95f3892dc2665747 425 Pfam PF05977 Transmembrane secretion effector 19 418 1.6E-29 T 28-03-2018 IPR010290 Transmembrane secretion effector CFK41_RS15030 8ef13933d007403821f783dc8942d329 338 SUPERFAMILY SSF51905 20 321 9.07E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS15030 8ef13933d007403821f783dc8942d329 338 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 245 261 3.1E-8 T 28-03-2018 CFK41_RS15030 8ef13933d007403821f783dc8942d329 338 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 126 144 3.1E-8 T 28-03-2018 CFK41_RS15030 8ef13933d007403821f783dc8942d329 338 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 25 44 3.1E-8 T 28-03-2018 CFK41_RS15030 8ef13933d007403821f783dc8942d329 338 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 277 299 3.1E-8 T 28-03-2018 CFK41_RS15030 8ef13933d007403821f783dc8942d329 338 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 24 310 3.4E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS15030 8ef13933d007403821f783dc8942d329 338 Gene3D G3DSA:3.50.50.60 20 153 1.6E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS15030 8ef13933d007403821f783dc8942d329 338 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 24 46 1.5E-11 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CFK41_RS15030 8ef13933d007403821f783dc8942d329 338 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 127 135 1.5E-11 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CFK41_RS15030 8ef13933d007403821f783dc8942d329 338 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 287 305 1.5E-11 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CFK41_RS15030 8ef13933d007403821f783dc8942d329 338 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 149 161 1.5E-11 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CFK41_RS15030 8ef13933d007403821f783dc8942d329 338 Gene3D G3DSA:3.50.50.60 154 251 1.0E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS07400 89801a5b27f474c3c27e34179b8251f1 358 SUPERFAMILY SSF51735 150 317 8.16E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS07400 89801a5b27f474c3c27e34179b8251f1 358 SUPERFAMILY SSF50129 6 174 6.7E-57 T 28-03-2018 IPR011032 GroES-like CFK41_RS07400 89801a5b27f474c3c27e34179b8251f1 358 Gene3D G3DSA:3.90.180.10 1 197 4.8E-59 T 28-03-2018 CFK41_RS07400 89801a5b27f474c3c27e34179b8251f1 358 Gene3D G3DSA:3.40.50.20 198 348 4.5E-19 T 28-03-2018 CFK41_RS07400 89801a5b27f474c3c27e34179b8251f1 358 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 63 77 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CFK41_RS07400 89801a5b27f474c3c27e34179b8251f1 358 Pfam PF00107 Zinc-binding dehydrogenase 191 313 2.1E-20 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CFK41_RS07400 89801a5b27f474c3c27e34179b8251f1 358 SMART SM00829 12 347 3.3E-6 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CFK41_RS07400 89801a5b27f474c3c27e34179b8251f1 358 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 144 2.5E-30 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CFK41_RS05875 6fb5a48854d6730b48dd30324e0841cc 293 SMART SM00331 23 249 3.0E-25 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CFK41_RS05875 6fb5a48854d6730b48dd30324e0841cc 293 Pfam PF13672 Protein phosphatase 2C 30 232 2.2E-9 T 28-03-2018 CFK41_RS05875 6fb5a48854d6730b48dd30324e0841cc 293 Gene3D G3DSA:3.60.40.10 41 249 4.0E-33 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CFK41_RS05875 6fb5a48854d6730b48dd30324e0841cc 293 SUPERFAMILY SSF81606 20 247 2.09E-51 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CFK41_RS05875 6fb5a48854d6730b48dd30324e0841cc 293 SMART SM00332 9 247 1.6E-14 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CFK41_RS16795 3bfc1933efc21be90d96766de2bc5fed 513 Pfam PF05154 TM2 domain 52 99 1.8E-16 T 28-03-2018 IPR007829 TM2 domain CFK41_RS16795 3bfc1933efc21be90d96766de2bc5fed 513 SMART SM00894 477 513 5.2E-20 T 28-03-2018 IPR008613 Excalibur calcium-binding domain CFK41_RS16795 3bfc1933efc21be90d96766de2bc5fed 513 Pfam PF07510 Protein of unknown function (DUF1524) 235 368 8.1E-19 T 28-03-2018 IPR011089 Domain of unknown function DUF1524 CFK41_RS16795 3bfc1933efc21be90d96766de2bc5fed 513 Pfam PF05901 Excalibur calcium-binding domain 478 513 4.9E-14 T 28-03-2018 IPR008613 Excalibur calcium-binding domain CFK41_RS07125 7c5c039b42151e44f2ee9346455e1d8a 298 Gene3D G3DSA:3.40.50.410 49 265 1.0E-16 T 28-03-2018 IPR002035 von Willebrand factor, type A CFK41_RS07125 7c5c039b42151e44f2ee9346455e1d8a 298 Pfam PF01882 Protein of unknown function DUF58 37 123 7.5E-19 T 28-03-2018 IPR002881 Domain of unknown function DUF58 CFK41_RS07125 7c5c039b42151e44f2ee9346455e1d8a 298 SUPERFAMILY SSF53300 77 237 9.64E-6 T 28-03-2018 IPR002035 von Willebrand factor, type A CFK41_RS02045 d4128972fee746e47e0a8951bda8936a 387 Gene3D G3DSA:3.50.50.60 1 351 1.8E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS02045 d4128972fee746e47e0a8951bda8936a 387 Pfam PF05834 Lycopene cyclase protein 2 44 4.0E-6 T 28-03-2018 CFK41_RS02045 d4128972fee746e47e0a8951bda8936a 387 Pfam PF01494 FAD binding domain 148 342 8.9E-14 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CFK41_RS02045 d4128972fee746e47e0a8951bda8936a 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 152 167 1.1E-12 T 28-03-2018 CFK41_RS02045 d4128972fee746e47e0a8951bda8936a 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 1.1E-12 T 28-03-2018 CFK41_RS02045 d4128972fee746e47e0a8951bda8936a 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 282 297 1.1E-12 T 28-03-2018 CFK41_RS02045 d4128972fee746e47e0a8951bda8936a 387 SUPERFAMILY SSF51905 269 370 3.39E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS02045 d4128972fee746e47e0a8951bda8936a 387 SUPERFAMILY SSF51905 1 173 3.39E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS10815 8dce591e0c7b846e5abe1163a40dcda6 570 Gene3D G3DSA:3.20.20.470 198 479 3.6E-38 T 28-03-2018 CFK41_RS10815 8dce591e0c7b846e5abe1163a40dcda6 570 Pfam PF00128 Alpha amylase, catalytic domain 48 411 2.7E-72 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CFK41_RS10815 8dce591e0c7b846e5abe1163a40dcda6 570 Gene3D G3DSA:3.90.400.10 140 197 7.7E-28 T 28-03-2018 CFK41_RS10815 8dce591e0c7b846e5abe1163a40dcda6 570 Gene3D G3DSA:3.20.20.80 9 139 2.2E-46 T 28-03-2018 CFK41_RS10815 8dce591e0c7b846e5abe1163a40dcda6 570 SMART SM00642 33 436 2.2E-113 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CFK41_RS10815 8dce591e0c7b846e5abe1163a40dcda6 570 SUPERFAMILY SSF51445 23 492 2.69E-119 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS00710 5589541619b4f31949572b54b11038da 312 Pfam PF02517 CAAX protease self-immunity 145 238 7.8E-18 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CFK41_RS06785 faa2e68f01f29ac67ceafd9f4702724e 115 SUPERFAMILY SSF89957 28 114 1.03E-24 T 28-03-2018 IPR029756 MTH1187/YkoF-like CFK41_RS06785 faa2e68f01f29ac67ceafd9f4702724e 115 Gene3D G3DSA:3.30.70.930 1 109 2.0E-33 T 28-03-2018 IPR029756 MTH1187/YkoF-like CFK41_RS06785 faa2e68f01f29ac67ceafd9f4702724e 115 Pfam PF01910 Thiamine-binding protein 26 107 1.7E-24 T 28-03-2018 IPR002767 Thiamine-binding protein CFK41_RS08100 f4560957039a7f29e1704c8a88fa89ad 380 Gene3D G3DSA:3.20.20.120 147 364 1.6E-67 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS08100 f4560957039a7f29e1704c8a88fa89ad 380 SUPERFAMILY SSF51604 127 368 2.36E-75 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS08100 f4560957039a7f29e1704c8a88fa89ad 380 SUPERFAMILY SSF54826 10 140 8.25E-28 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS08100 f4560957039a7f29e1704c8a88fa89ad 380 SMART SM00922 159 256 8.1E-28 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CFK41_RS08100 f4560957039a7f29e1704c8a88fa89ad 380 Pfam PF13378 Enolase C-terminal domain-like 161 366 1.9E-66 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CFK41_RS08100 f4560957039a7f29e1704c8a88fa89ad 380 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 43 139 2.2E-13 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CFK41_RS08100 f4560957039a7f29e1704c8a88fa89ad 380 Gene3D G3DSA:3.30.390.10 4 146 1.5E-30 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CFK41_RS08100 f4560957039a7f29e1704c8a88fa89ad 380 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 206 237 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CFK41_RS08100 f4560957039a7f29e1704c8a88fa89ad 380 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 114 139 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CFK41_RS14100 e9783863a3f629f36bec1b7d1321e156 299 Pfam PF01636 Phosphotransferase enzyme family 45 222 4.8E-21 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CFK41_RS14100 e9783863a3f629f36bec1b7d1321e156 299 SUPERFAMILY SSF56112 16 247 4.23E-31 T 28-03-2018 IPR011009 Protein kinase-like domain CFK41_RS14100 e9783863a3f629f36bec1b7d1321e156 299 Gene3D G3DSA:3.30.200.20 8 100 4.5E-10 T 28-03-2018 CFK41_RS14100 e9783863a3f629f36bec1b7d1321e156 299 Gene3D G3DSA:3.90.1200.10 101 256 1.6E-14 T 28-03-2018 CFK41_RS06870 b9d0ddea9b086804d266a65e79ee786e 406 SUPERFAMILY SSF53784 3 401 4.97E-77 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CFK41_RS06870 b9d0ddea9b086804d266a65e79ee786e 406 Hamap MF_01977 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 2 399 61.407 T 28-03-2018 IPR011405 Pyrophosphate-dependent phosphofructokinase SMc01852 type GO:0006096|GO:0047334 KEGG: 00010+2.7.1.90|KEGG: 00030+2.7.1.90|KEGG: 00051+2.7.1.90|MetaCyc: PWY-1042 CFK41_RS06870 b9d0ddea9b086804d266a65e79ee786e 406 Gene3D G3DSA:3.40.50.450 1 258 5.1E-45 T 28-03-2018 CFK41_RS06870 b9d0ddea9b086804d266a65e79ee786e 406 Pfam PF00365 Phosphofructokinase 5 348 1.5E-35 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CFK41_RS06870 b9d0ddea9b086804d266a65e79ee786e 406 PIRSF PIRSF036484 1 403 5.5E-205 T 28-03-2018 IPR011405 Pyrophosphate-dependent phosphofructokinase SMc01852 type GO:0006096|GO:0047334 KEGG: 00010+2.7.1.90|KEGG: 00030+2.7.1.90|KEGG: 00051+2.7.1.90|MetaCyc: PWY-1042 CFK41_RS06870 b9d0ddea9b086804d266a65e79ee786e 406 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 112 128 4.6E-14 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CFK41_RS06870 b9d0ddea9b086804d266a65e79ee786e 406 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 145 162 4.6E-14 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CFK41_RS06870 b9d0ddea9b086804d266a65e79ee786e 406 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 184 200 4.6E-14 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CFK41_RS06870 b9d0ddea9b086804d266a65e79ee786e 406 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 8 27 4.6E-14 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CFK41_RS05745 abe8787a81da39c3dcea37f601755324 358 SUPERFAMILY SSF51445 13 336 1.14E-49 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS05745 abe8787a81da39c3dcea37f601755324 358 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 12 329 1.4E-27 T 28-03-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CFK41_RS05745 abe8787a81da39c3dcea37f601755324 358 Gene3D G3DSA:3.20.20.80 9 348 2.2E-51 T 28-03-2018 CFK41_RS10710 41ef605fe4b036f61e605b02bee93d1e 425 Pfam PF07690 Major Facilitator Superfamily 262 413 8.8E-9 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS10710 41ef605fe4b036f61e605b02bee93d1e 425 Gene3D G3DSA:1.20.1250.20 20 208 2.2E-13 T 28-03-2018 CFK41_RS10710 41ef605fe4b036f61e605b02bee93d1e 425 Gene3D G3DSA:1.20.1250.20 237 425 1.1E-11 T 28-03-2018 CFK41_RS10710 41ef605fe4b036f61e605b02bee93d1e 425 SUPERFAMILY SSF103473 9 419 2.22E-31 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS10660 ed5074e6fab8eee19d0a8fd43963f396 986 Gene3D G3DSA:1.10.730.10 784 923 1.5E-25 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS10660 ed5074e6fab8eee19d0a8fd43963f396 986 Gene3D G3DSA:3.40.50.620 6 328 4.0E-61 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS10660 ed5074e6fab8eee19d0a8fd43963f396 986 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 319 523 1.2E-49 T 28-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 CFK41_RS10660 ed5074e6fab8eee19d0a8fd43963f396 986 SUPERFAMILY SSF52374 246 324 1.69E-105 T 28-03-2018 CFK41_RS10660 ed5074e6fab8eee19d0a8fd43963f396 986 SUPERFAMILY SSF52374 537 799 1.69E-105 T 28-03-2018 CFK41_RS10660 ed5074e6fab8eee19d0a8fd43963f396 986 SUPERFAMILY SSF52374 15 174 1.69E-105 T 28-03-2018 CFK41_RS10660 ed5074e6fab8eee19d0a8fd43963f396 986 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 246 986 2.1E-206 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CFK41_RS10660 ed5074e6fab8eee19d0a8fd43963f396 986 Gene3D G3DSA:3.90.740.10 329 530 7.3E-41 T 28-03-2018 CFK41_RS10660 ed5074e6fab8eee19d0a8fd43963f396 986 Gene3D G3DSA:3.40.50.620 531 783 1.8E-46 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS10660 ed5074e6fab8eee19d0a8fd43963f396 986 SUPERFAMILY SSF50677 321 540 7.72E-36 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CFK41_RS10660 ed5074e6fab8eee19d0a8fd43963f396 986 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 10 986 21.085 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CFK41_RS10660 ed5074e6fab8eee19d0a8fd43963f396 986 Pfam PF09334 tRNA synthetases class I (M) 63 169 1.7E-13 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS10660 ed5074e6fab8eee19d0a8fd43963f396 986 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 70 80 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS10660 ed5074e6fab8eee19d0a8fd43963f396 986 SUPERFAMILY SSF47323 799 986 2.24E-29 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS10660 ed5074e6fab8eee19d0a8fd43963f396 986 Pfam PF08264 Anticodon-binding domain of tRNA 836 946 2.1E-13 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CFK41_RS10660 ed5074e6fab8eee19d0a8fd43963f396 986 PRINTS PR00985 Leucyl-tRNA synthetase signature 704 714 4.3E-32 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CFK41_RS10660 ed5074e6fab8eee19d0a8fd43963f396 986 PRINTS PR00985 Leucyl-tRNA synthetase signature 671 693 4.3E-32 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CFK41_RS10660 ed5074e6fab8eee19d0a8fd43963f396 986 PRINTS PR00985 Leucyl-tRNA synthetase signature 154 171 4.3E-32 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CFK41_RS10660 ed5074e6fab8eee19d0a8fd43963f396 986 PRINTS PR00985 Leucyl-tRNA synthetase signature 623 641 4.3E-32 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CFK41_RS12790 6c73c6ac15909a0c27993a3664376f68 325 Gene3D G3DSA:3.30.420.40 134 324 2.7E-44 T 28-03-2018 CFK41_RS12790 6c73c6ac15909a0c27993a3664376f68 325 Gene3D G3DSA:3.30.420.40 2 133 2.4E-22 T 28-03-2018 CFK41_RS12790 6c73c6ac15909a0c27993a3664376f68 325 SUPERFAMILY SSF53067 4 314 5.56E-50 T 28-03-2018 CFK41_RS12790 6c73c6ac15909a0c27993a3664376f68 325 Pfam PF00480 ROK family 6 311 1.0E-45 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CFK41_RS11530 9b28b7c145659e8dbc45c81572ca8ebb 331 PIRSF PIRSF004486 9 325 5.6E-89 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CFK41_RS11530 9b28b7c145659e8dbc45c81572ca8ebb 331 Pfam PF01795 MraW methylase family 13 323 1.3E-98 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CFK41_RS11530 9b28b7c145659e8dbc45c81572ca8ebb 331 Gene3D G3DSA:3.40.50.150 18 129 1.0E-10 T 28-03-2018 CFK41_RS11530 9b28b7c145659e8dbc45c81572ca8ebb 331 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 14 324 33.938 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CFK41_RS11530 9b28b7c145659e8dbc45c81572ca8ebb 331 SUPERFAMILY SSF53335 14 126 8.65E-36 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS11530 9b28b7c145659e8dbc45c81572ca8ebb 331 SUPERFAMILY SSF53335 229 323 8.65E-36 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS11530 9b28b7c145659e8dbc45c81572ca8ebb 331 SUPERFAMILY SSF81799 127 229 3.92E-31 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CFK41_RS11530 9b28b7c145659e8dbc45c81572ca8ebb 331 Gene3D G3DSA:1.10.150.170 130 231 1.3E-34 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CFK41_RS11530 9b28b7c145659e8dbc45c81572ca8ebb 331 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 12 322 5.4E-84 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CFK41_RS02600 d7952dddac7421523bd8bfdf5c637793 628 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 272 509 2.5E-31 T 28-03-2018 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 CFK41_RS02600 d7952dddac7421523bd8bfdf5c637793 628 Gene3D G3DSA:1.50.10.10 16 343 1.3E-10 T 28-03-2018 CFK41_RS02600 d7952dddac7421523bd8bfdf5c637793 628 SUPERFAMILY SSF48208 35 339 1.43E-10 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CFK41_RS12985 c813e198ee5a7ed5de689db1b4363e9a 651 Gene3D G3DSA:2.60.120.260 36 213 1.1E-37 T 28-03-2018 IPR008979 Galactose-binding domain-like CFK41_RS12985 c813e198ee5a7ed5de689db1b4363e9a 651 SUPERFAMILY SSF51445 537 640 4.59E-48 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS12985 c813e198ee5a7ed5de689db1b4363e9a 651 SUPERFAMILY SSF51445 315 497 4.59E-48 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS12985 c813e198ee5a7ed5de689db1b4363e9a 651 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 407 482 2.1E-7 T 28-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 CFK41_RS12985 c813e198ee5a7ed5de689db1b4363e9a 651 SUPERFAMILY SSF49785 36 213 2.41E-43 T 28-03-2018 IPR008979 Galactose-binding domain-like CFK41_RS12985 c813e198ee5a7ed5de689db1b4363e9a 651 SUPERFAMILY SSF49303 229 317 7.77E-9 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CFK41_RS12985 c813e198ee5a7ed5de689db1b4363e9a 651 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 54 209 1.3E-11 T 28-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CFK41_RS12985 c813e198ee5a7ed5de689db1b4363e9a 651 Pfam PF00703 Glycosyl hydrolases family 2 248 317 5.9E-5 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CFK41_RS12985 c813e198ee5a7ed5de689db1b4363e9a 651 Gene3D G3DSA:3.20.20.80 319 641 5.1E-29 T 28-03-2018 CFK41_RS12985 c813e198ee5a7ed5de689db1b4363e9a 651 Gene3D G3DSA:2.60.40.10 216 317 1.3E-9 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS04640 321e44c28876d0b901d81e087a5a64f1 128 SUPERFAMILY SSF50104 2 125 1.28E-27 T 28-03-2018 IPR008991 Translation protein SH3-like domain CFK41_RS04640 321e44c28876d0b901d81e087a5a64f1 128 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 4 122 21.284 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04640 321e44c28876d0b901d81e087a5a64f1 128 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 33 128 3.0E-26 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04640 321e44c28876d0b901d81e087a5a64f1 128 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 56 128 1.1E-24 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04640 321e44c28876d0b901d81e087a5a64f1 128 Gene3D G3DSA:2.30.30.30 1 108 5.6E-37 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CFK41_RS06655 95ccad88b0a7387b9bc9ef23c5cd134c 251 SUPERFAMILY SSF51735 3 241 5.67E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS06655 95ccad88b0a7387b9bc9ef23c5cd134c 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.6E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS06655 95ccad88b0a7387b9bc9ef23c5cd134c 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 3.6E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS06655 95ccad88b0a7387b9bc9ef23c5cd134c 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.6E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS06655 95ccad88b0a7387b9bc9ef23c5cd134c 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 3.6E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS06655 95ccad88b0a7387b9bc9ef23c5cd134c 251 Gene3D G3DSA:3.40.50.720 1 250 1.2E-36 T 28-03-2018 CFK41_RS06655 95ccad88b0a7387b9bc9ef23c5cd134c 251 Pfam PF00106 short chain dehydrogenase 7 191 1.9E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS07390 9580a52ade4a8e03a69eee90b7429482 163 Pfam PF12028 Protein of unknown function (DUF3515) 29 153 4.8E-18 T 28-03-2018 IPR021903 Protein of unknown function DUF3515 CFK41_RS11815 de8c6e876e04af8edd3c5ecf18164876 125 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 37 68 3.2E-9 T 28-03-2018 IPR019933 DivIVA domain CFK41_RS11815 de8c6e876e04af8edd3c5ecf18164876 125 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 2 30 5.6E-9 T 28-03-2018 IPR019933 DivIVA domain CFK41_RS08095 2e18b8edaa5e2e0616b627f813687a81 197 Gene3D G3DSA:2.70.70.10 15 182 1.1E-20 T 28-03-2018 CFK41_RS08095 2e18b8edaa5e2e0616b627f813687a81 197 Pfam PF01551 Peptidase family M23 61 173 2.2E-11 T 28-03-2018 IPR016047 Peptidase M23 CFK41_RS08095 2e18b8edaa5e2e0616b627f813687a81 197 SUPERFAMILY SSF51261 58 75 5.02E-15 T 28-03-2018 IPR011055 Duplicated hybrid motif CFK41_RS08095 2e18b8edaa5e2e0616b627f813687a81 197 SUPERFAMILY SSF51261 104 170 5.02E-15 T 28-03-2018 IPR011055 Duplicated hybrid motif CFK41_RS09785 955fd32e970edfe49805c878df0d4c2a 377 SUPERFAMILY SSF48576 23 350 1.5E-58 T 28-03-2018 IPR008949 Isoprenoid synthase domain CFK41_RS09785 955fd32e970edfe49805c878df0d4c2a 377 Gene3D G3DSA:1.10.600.10 15 371 1.9E-68 T 28-03-2018 IPR008949 Isoprenoid synthase domain CFK41_RS09785 955fd32e970edfe49805c878df0d4c2a 377 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 103 117 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CFK41_RS09785 955fd32e970edfe49805c878df0d4c2a 377 Pfam PF00348 Polyprenyl synthetase 52 323 9.8E-46 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CFK41_RS07895 79488343ef212a95da1c898cfcdfea36 309 SUPERFAMILY SSF52540 17 275 1.97E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS07895 79488343ef212a95da1c898cfcdfea36 309 Gene3D G3DSA:3.40.50.300 16 305 9.3E-58 T 28-03-2018 CFK41_RS07895 79488343ef212a95da1c898cfcdfea36 309 SMART SM00382 45 257 5.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS07895 79488343ef212a95da1c898cfcdfea36 309 Pfam PF00005 ABC transporter 37 199 2.8E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS07895 79488343ef212a95da1c898cfcdfea36 309 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 251 287 2.7E-6 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CFK41_RS16340 ce9f89bb2b5d263e288ad1051691e1a7 522 Gene3D G3DSA:2.60.40.1180 449 522 5.5E-10 T 28-03-2018 CFK41_RS16340 ce9f89bb2b5d263e288ad1051691e1a7 522 Gene3D G3DSA:3.20.20.80 105 448 1.2E-62 T 28-03-2018 CFK41_RS16340 ce9f89bb2b5d263e288ad1051691e1a7 522 SUPERFAMILY SSF51445 107 455 1.15E-50 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS16340 ce9f89bb2b5d263e288ad1051691e1a7 522 Pfam PF02055 Glycosyl hydrolase family 30 TIM-barrel domain 107 452 2.0E-26 T 28-03-2018 IPR033453 Glycosyl hydrolase family 30, TIM-barrel domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 CFK41_RS16340 ce9f89bb2b5d263e288ad1051691e1a7 522 Pfam PF17189 Glycosyl hydrolase family 30 beta sandwich domain 461 513 2.3E-7 T 28-03-2018 IPR033452 Glycosyl hydrolase family 30, beta sandwich domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 CFK41_RS04450 33993b7ec2fc3fe1953e4455cc9bf55d 496 Pfam PF12821 Threonine/Serine exporter, ThrE 286 404 1.9E-15 T 28-03-2018 IPR024528 Threonine/Serine exporter, ThrE CFK41_RS04450 33993b7ec2fc3fe1953e4455cc9bf55d 496 Pfam PF06738 Putative threonine/serine exporter 13 254 4.6E-44 T 28-03-2018 IPR010619 Putative threonine/serine exporter CFK41_RS06085 c9492f0993c1b053df3fe6990f87fec4 285 Pfam PF01048 Phosphorylase superfamily 29 267 1.2E-37 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CFK41_RS06085 c9492f0993c1b053df3fe6990f87fec4 285 TIGRFAM TIGR01698 PUNP: purine nucleotide phosphorylase 29 267 2.0E-96 T 28-03-2018 IPR011269 Putative purine nucleotide phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 CFK41_RS06085 c9492f0993c1b053df3fe6990f87fec4 285 Gene3D G3DSA:3.40.50.1580 1 270 1.1E-54 T 28-03-2018 CFK41_RS06085 c9492f0993c1b053df3fe6990f87fec4 285 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 30 267 4.2E-68 T 28-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CFK41_RS06085 c9492f0993c1b053df3fe6990f87fec4 285 SUPERFAMILY SSF53167 9 270 3.76E-74 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CFK41_RS06085 c9492f0993c1b053df3fe6990f87fec4 285 PIRSF PIRSF000477 1 270 3.7E-79 T 28-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CFK41_RS13735 304b46e4a68ad2cd5a7f2da4dcce723b 262 Pfam PF12698 ABC-2 family transporter protein 70 248 7.8E-11 T 28-03-2018 CFK41_RS01850 522f4baf0ccb45c7136d84a5db7cc9a4 367 SUPERFAMILY SSF47413 3 62 1.45E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS01850 522f4baf0ccb45c7136d84a5db7cc9a4 367 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 51 9.6E-14 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS01850 522f4baf0ccb45c7136d84a5db7cc9a4 367 SUPERFAMILY SSF53822 61 325 1.35E-46 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS01850 522f4baf0ccb45c7136d84a5db7cc9a4 367 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 28-03-2018 CFK41_RS01850 522f4baf0ccb45c7136d84a5db7cc9a4 367 Pfam PF13377 Periplasmic binding protein-like domain 179 321 7.7E-23 T 28-03-2018 CFK41_RS01850 522f4baf0ccb45c7136d84a5db7cc9a4 367 Gene3D G3DSA:3.40.50.2300 184 326 5.4E-33 T 28-03-2018 CFK41_RS01850 522f4baf0ccb45c7136d84a5db7cc9a4 367 SMART SM00354 3 74 2.3E-22 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS01850 522f4baf0ccb45c7136d84a5db7cc9a4 367 Gene3D G3DSA:1.10.260.40 4 56 1.4E-18 T 28-03-2018 CFK41_RS01850 522f4baf0ccb45c7136d84a5db7cc9a4 367 Gene3D G3DSA:3.40.50.2300 57 183 3.1E-25 T 28-03-2018 CFK41_RS02130 ee2c0b9b5169011c5b4704e6c65ee0d7 485 Gene3D G3DSA:1.10.3860.10 19 439 1.3E-109 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CFK41_RS02130 ee2c0b9b5169011c5b4704e6c65ee0d7 485 SUPERFAMILY SSF118215 28 433 3.14E-101 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CFK41_RS02130 ee2c0b9b5169011c5b4704e6c65ee0d7 485 PRINTS PR00173 Glutamate-aspartate symporter signature 104 129 6.8E-24 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CFK41_RS02130 ee2c0b9b5169011c5b4704e6c65ee0d7 485 PRINTS PR00173 Glutamate-aspartate symporter signature 21 41 6.8E-24 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CFK41_RS02130 ee2c0b9b5169011c5b4704e6c65ee0d7 485 PRINTS PR00173 Glutamate-aspartate symporter signature 386 406 6.8E-24 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CFK41_RS02130 ee2c0b9b5169011c5b4704e6c65ee0d7 485 PRINTS PR00173 Glutamate-aspartate symporter signature 224 243 6.8E-24 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CFK41_RS02130 ee2c0b9b5169011c5b4704e6c65ee0d7 485 PRINTS PR00173 Glutamate-aspartate symporter signature 177 199 6.8E-24 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CFK41_RS02130 ee2c0b9b5169011c5b4704e6c65ee0d7 485 PRINTS PR00173 Glutamate-aspartate symporter signature 324 350 6.8E-24 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CFK41_RS02130 ee2c0b9b5169011c5b4704e6c65ee0d7 485 Pfam PF00375 Sodium:dicarboxylate symporter family 29 431 3.8E-107 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CFK41_RS11330 b5e6228d84d844445f97fed511c499da 324 SUPERFAMILY SSF51161 77 304 1.26E-35 T 28-03-2018 IPR011004 Trimeric LpxA-like CFK41_RS11330 b5e6228d84d844445f97fed511c499da 324 Pfam PF14789 Tetrahydrodipicolinate N-succinyltransferase middle 112 152 3.7E-18 T 28-03-2018 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 CFK41_RS11330 b5e6228d84d844445f97fed511c499da 324 TIGRFAM TIGR03535 DapD_actino: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 12 324 2.7E-151 T 28-03-2018 IPR019875 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, actinobacteria KEGG: 00300+2.3.1.117 CFK41_RS11330 b5e6228d84d844445f97fed511c499da 324 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 234 266 2.9E-13 T 28-03-2018 IPR001451 Hexapeptide repeat CFK41_RS11330 b5e6228d84d844445f97fed511c499da 324 Hamap MF_02122 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 10 322 42.838 T 28-03-2018 IPR026586 Type 2 tetrahydrodipicolinate N-succinyltransferase family GO:0008666 KEGG: 00300+2.3.1.117 CFK41_RS11330 b5e6228d84d844445f97fed511c499da 324 Gene3D G3DSA:2.160.10.10 153 322 9.8E-18 T 28-03-2018 CFK41_RS11330 b5e6228d84d844445f97fed511c499da 324 Gene3D G3DSA:3.30.60.70 112 152 4.5E-19 T 28-03-2018 CFK41_RS00375 c8d03b4d68d2f7d2360571977a5055a7 159 Gene3D G3DSA:3.40.630.30 72 153 3.0E-8 T 28-03-2018 CFK41_RS00375 c8d03b4d68d2f7d2360571977a5055a7 159 SUPERFAMILY SSF55729 11 134 3.84E-14 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS00375 c8d03b4d68d2f7d2360571977a5055a7 159 Gene3D G3DSA:3.40.630.30 6 71 1.9E-5 T 28-03-2018 CFK41_RS00375 c8d03b4d68d2f7d2360571977a5055a7 159 Pfam PF00583 Acetyltransferase (GNAT) family 52 134 2.5E-5 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS01965 f1a7786e811ce3c86789925596039d6b 181 SUPERFAMILY SSF55729 5 154 2.76E-38 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS01965 f1a7786e811ce3c86789925596039d6b 181 Gene3D G3DSA:3.40.630.30 2 167 3.4E-27 T 28-03-2018 CFK41_RS01965 f1a7786e811ce3c86789925596039d6b 181 Pfam PF13302 Acetyltransferase (GNAT) domain 11 148 8.8E-32 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS03070 556d049a6bcb74d37e16b6191674fe0e 343 Gene3D G3DSA:3.40.190.10 139 268 2.0E-23 T 28-03-2018 CFK41_RS03070 556d049a6bcb74d37e16b6191674fe0e 343 Gene3D G3DSA:3.40.190.10 43 138 6.8E-10 T 28-03-2018 CFK41_RS03070 556d049a6bcb74d37e16b6191674fe0e 343 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 54 289 2.6E-53 T 28-03-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 CFK41_RS03070 556d049a6bcb74d37e16b6191674fe0e 343 SUPERFAMILY SSF53850 48 275 1.42E-41 T 28-03-2018 CFK41_RS03070 556d049a6bcb74d37e16b6191674fe0e 343 Pfam PF09084 NMT1/THI5 like 76 260 7.7E-19 T 28-03-2018 IPR015168 SsuA/THI5-like CFK41_RS02900 9f5e224a31d04837bd715ee2b480ff3f 767 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 553 739 3.0E-14 T 28-03-2018 CFK41_RS02900 9f5e224a31d04837bd715ee2b480ff3f 767 Pfam PF07993 Male sterility protein 25 353 3.2E-49 T 28-03-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CFK41_RS02900 9f5e224a31d04837bd715ee2b480ff3f 767 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 553 750 1.8E-33 T 28-03-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like CFK41_RS02900 9f5e224a31d04837bd715ee2b480ff3f 767 Gene3D G3DSA:3.40.50.720 17 478 1.0E-45 T 28-03-2018 CFK41_RS02900 9f5e224a31d04837bd715ee2b480ff3f 767 Gene3D G3DSA:3.40.50.1000 521 759 5.6E-13 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS02900 9f5e224a31d04837bd715ee2b480ff3f 767 SUPERFAMILY SSF51735 21 57 3.36E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS02900 9f5e224a31d04837bd715ee2b480ff3f 767 SUPERFAMILY SSF51735 94 178 3.36E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS02900 9f5e224a31d04837bd715ee2b480ff3f 767 SUPERFAMILY SSF51735 244 473 3.36E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS02900 9f5e224a31d04837bd715ee2b480ff3f 767 SUPERFAMILY SSF56784 552 751 2.34E-22 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS02900 9f5e224a31d04837bd715ee2b480ff3f 767 Pfam PF12710 haloacid dehalogenase-like hydrolase 554 737 2.7E-31 T 28-03-2018 CFK41_RS02900 9f5e224a31d04837bd715ee2b480ff3f 767 Pfam PF03015 Male sterility protein 463 516 8.8E-9 T 28-03-2018 IPR033640 Fatty acyl-CoA reductase, C-terminal Reactome: R-HSA-8848584 CFK41_RS14670 4e3b564e7cf0cd1cd4d2d1a436e42f1b 372 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 118 135 - T 28-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CFK41_RS14670 4e3b564e7cf0cd1cd4d2d1a436e42f1b 372 Pfam PF00701 Dihydrodipicolinate synthetase family 85 344 8.8E-41 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS14670 4e3b564e7cf0cd1cd4d2d1a436e42f1b 372 PRINTS PR00146 Dihydrodipicolinate synthase signature 182 198 2.3E-12 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS14670 4e3b564e7cf0cd1cd4d2d1a436e42f1b 372 PRINTS PR00146 Dihydrodipicolinate synthase signature 115 136 2.3E-12 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS14670 4e3b564e7cf0cd1cd4d2d1a436e42f1b 372 PRINTS PR00146 Dihydrodipicolinate synthase signature 150 168 2.3E-12 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS14670 4e3b564e7cf0cd1cd4d2d1a436e42f1b 372 Gene3D G3DSA:3.20.20.70 69 368 2.7E-55 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS14670 4e3b564e7cf0cd1cd4d2d1a436e42f1b 372 SUPERFAMILY SSF51569 86 367 3.66E-52 T 28-03-2018 CFK41_RS14670 4e3b564e7cf0cd1cd4d2d1a436e42f1b 372 SMART SM01130 82 365 2.1E-49 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS10840 8a853b6e056b81ae53e3cc52e784b357 240 Pfam PF09335 SNARE associated Golgi protein 113 229 7.0E-20 T 28-03-2018 IPR032816 SNARE associated Golgi protein CFK41_RS15185 c1cc7bbc90c0e47415a7502d1156e025 704 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 445 572 4.7E-30 T 28-03-2018 IPR025299 CstA, C-terminal domain CFK41_RS15185 c1cc7bbc90c0e47415a7502d1156e025 704 Pfam PF02554 Carbon starvation protein CstA 10 387 4.3E-161 T 28-03-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 CFK41_RS03545 17294cac78392d38e47813764c389ca8 106 Pfam PF10724 Protein of unknown function (DUF2516) 5 98 3.1E-28 T 28-03-2018 IPR019662 Protein of unknown function DUF2516 CFK41_RS04115 61514ae60ca7dd068ccb0d2a706fe2b1 169 SUPERFAMILY SSF52540 2 145 7.44E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS04115 61514ae60ca7dd068ccb0d2a706fe2b1 169 Gene3D G3DSA:3.40.50.300 1 165 4.9E-15 T 28-03-2018 CFK41_RS15895 197b1dfe5a679f3227380b552a3ba97e 476 SUPERFAMILY SSF103473 257 460 3.4E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS15895 197b1dfe5a679f3227380b552a3ba97e 476 SUPERFAMILY SSF103473 10 204 3.4E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS15895 197b1dfe5a679f3227380b552a3ba97e 476 Pfam PF07690 Major Facilitator Superfamily 25 422 2.8E-47 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS15895 197b1dfe5a679f3227380b552a3ba97e 476 Gene3D G3DSA:1.20.1250.20 269 473 2.3E-20 T 28-03-2018 CFK41_RS15895 197b1dfe5a679f3227380b552a3ba97e 476 PRINTS PR01036 Tetracycline resistance protein TetB signature 20 44 4.1E-6 T 28-03-2018 CFK41_RS15895 197b1dfe5a679f3227380b552a3ba97e 476 PRINTS PR01036 Tetracycline resistance protein TetB signature 141 165 4.1E-6 T 28-03-2018 CFK41_RS15895 197b1dfe5a679f3227380b552a3ba97e 476 PRINTS PR01036 Tetracycline resistance protein TetB signature 80 102 4.1E-6 T 28-03-2018 CFK41_RS15895 197b1dfe5a679f3227380b552a3ba97e 476 Gene3D G3DSA:1.20.1250.20 11 205 3.7E-32 T 28-03-2018 CFK41_RS13345 4f01a62d681ec046eeaf28af5826c75b 330 SUPERFAMILY SSF53822 64 323 4.52E-52 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS13345 4f01a62d681ec046eeaf28af5826c75b 330 SUPERFAMILY SSF47413 2 59 8.72E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS13345 4f01a62d681ec046eeaf28af5826c75b 330 Gene3D G3DSA:3.40.50.2300 54 171 5.4E-29 T 28-03-2018 CFK41_RS13345 4f01a62d681ec046eeaf28af5826c75b 330 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 8.3E-14 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS13345 4f01a62d681ec046eeaf28af5826c75b 330 Gene3D G3DSA:1.10.260.40 1 53 6.9E-19 T 28-03-2018 CFK41_RS13345 4f01a62d681ec046eeaf28af5826c75b 330 SMART SM00354 2 72 4.2E-22 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS13345 4f01a62d681ec046eeaf28af5826c75b 330 Gene3D G3DSA:3.40.50.2300 172 304 3.3E-33 T 28-03-2018 CFK41_RS13345 4f01a62d681ec046eeaf28af5826c75b 330 Pfam PF13377 Periplasmic binding protein-like domain 165 319 2.5E-26 T 28-03-2018 CFK41_RS09855 dbb4bc38ed361e57037165b0d5b3102b 363 Pfam PF00355 Rieske [2Fe-2S] domain 268 324 3.8E-10 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CFK41_RS09855 dbb4bc38ed361e57037165b0d5b3102b 363 SUPERFAMILY SSF50022 214 349 2.49E-28 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CFK41_RS09855 dbb4bc38ed361e57037165b0d5b3102b 363 Gene3D G3DSA:2.102.10.10 201 352 9.7E-36 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CFK41_RS09855 dbb4bc38ed361e57037165b0d5b3102b 363 PRINTS PR00162 Rieske 2Fe-2S subunit signature 308 320 9.0E-5 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CFK41_RS09855 dbb4bc38ed361e57037165b0d5b3102b 363 PRINTS PR00162 Rieske 2Fe-2S subunit signature 294 306 9.0E-5 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CFK41_RS09855 dbb4bc38ed361e57037165b0d5b3102b 363 PRINTS PR00162 Rieske 2Fe-2S subunit signature 272 283 9.0E-5 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CFK41_RS09855 dbb4bc38ed361e57037165b0d5b3102b 363 Gene3D G3DSA:1.20.1250.20 46 200 6.8E-4 T 28-03-2018 CFK41_RS08895 835140e9f7cf20aa1921d0a42f590566 903 Gene3D G3DSA:1.20.120.570 341 504 0.0012 T 28-03-2018 CFK41_RS08895 835140e9f7cf20aa1921d0a42f590566 903 Gene3D G3DSA:1.20.120.570 505 677 2.7E-18 T 28-03-2018 CFK41_RS08895 835140e9f7cf20aa1921d0a42f590566 903 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 199 225 2.9E-5 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CFK41_RS08895 835140e9f7cf20aa1921d0a42f590566 903 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 619 646 2.2E-7 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CFK41_RS08895 835140e9f7cf20aa1921d0a42f590566 903 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 641 667 8.8E-5 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CFK41_RS08895 835140e9f7cf20aa1921d0a42f590566 903 Pfam PF12698 ABC-2 family transporter protein 8 156 2.1E-12 T 28-03-2018 CFK41_RS08895 835140e9f7cf20aa1921d0a42f590566 903 Gene3D G3DSA:1.10.287.950 211 282 5.6E-7 T 28-03-2018 CFK41_RS08895 835140e9f7cf20aa1921d0a42f590566 903 Gene3D G3DSA:3.40.1710.10 32 210 6.5E-21 T 28-03-2018 CFK41_RS04340 78d4b7b46071d0dd12fbe3e3e6b2009c 194 Gene3D G3DSA:3.40.30.10 46 194 1.2E-25 T 28-03-2018 CFK41_RS04340 78d4b7b46071d0dd12fbe3e3e6b2009c 194 Pfam PF00578 AhpC/TSA family 61 173 6.3E-16 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CFK41_RS04340 78d4b7b46071d0dd12fbe3e3e6b2009c 194 SUPERFAMILY SSF52833 61 193 1.82E-29 T 28-03-2018 IPR012336 Thioredoxin-like fold CFK41_RS08775 91e4ee5cffbdac21fa716cfea9b1bb64 270 SUPERFAMILY SSF51695 23 267 3.4E-45 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CFK41_RS08775 91e4ee5cffbdac21fa716cfea9b1bb64 270 Gene3D G3DSA:3.20.20.190 17 270 2.0E-45 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CFK41_RS08775 91e4ee5cffbdac21fa716cfea9b1bb64 270 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 30 261 1.3E-24 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CFK41_RS10870 0b0d9bba4e85bc7aa800862ee36960ea 138 Pfam PF04237 YjbR 16 106 3.1E-23 T 28-03-2018 IPR007351 Uncharacterised protein YjbR CFK41_RS10870 0b0d9bba4e85bc7aa800862ee36960ea 138 SUPERFAMILY SSF142906 10 117 3.27E-33 T 28-03-2018 CFK41_RS03465 2d2333459113b02f512212b5b4640bf4 331 Gene3D G3DSA:1.20.144.10 29 236 5.2E-15 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CFK41_RS03465 2d2333459113b02f512212b5b4640bf4 331 SMART SM00014 108 212 0.0034 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CFK41_RS03465 2d2333459113b02f512212b5b4640bf4 331 SUPERFAMILY SSF48317 38 229 1.57E-16 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CFK41_RS03465 2d2333459113b02f512212b5b4640bf4 331 Pfam PF01569 PAP2 superfamily 141 213 1.8E-9 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CFK41_RS15040 94162cef1ca9980613b3dad5cc01b278 352 Gene3D G3DSA:3.30.1220.10 218 319 8.7E-11 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CFK41_RS15040 94162cef1ca9980613b3dad5cc01b278 352 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 33 166 2.1E-4 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CFK41_RS15040 94162cef1ca9980613b3dad5cc01b278 352 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 233 319 1.3E-13 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CFK41_RS15040 94162cef1ca9980613b3dad5cc01b278 352 SUPERFAMILY SSF90002 234 319 1.01E-5 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CFK41_RS15040 94162cef1ca9980613b3dad5cc01b278 352 SMART SM00833 230 321 1.7E-13 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CFK41_RS11190 c52439f8006c25ea88330f093974722e 539 SUPERFAMILY SSF55486 74 439 1.61E-83 T 28-03-2018 CFK41_RS11190 c52439f8006c25ea88330f093974722e 539 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 75 439 1.2E-79 T 28-03-2018 IPR018766 Zinicin-like metallopeptidase type 2 CFK41_RS11190 c52439f8006c25ea88330f093974722e 539 Pfam PF10103 Zincin-like metallopeptidase 75 438 8.9E-95 T 28-03-2018 IPR018766 Zinicin-like metallopeptidase type 2 CFK41_RS15630 41aada110172b07052b3f65a980e1581 612 SUPERFAMILY SSF52540 363 583 2.01E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS15630 41aada110172b07052b3f65a980e1581 612 Gene3D G3DSA:3.40.50.300 361 592 3.6E-18 T 28-03-2018 CFK41_RS11380 395e2930ed3c7df74c4b8cc30b56a0aa 319 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 40 92 4.9E-7 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CFK41_RS11380 395e2930ed3c7df74c4b8cc30b56a0aa 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 133 318 1.9E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS11380 395e2930ed3c7df74c4b8cc30b56a0aa 319 Gene3D G3DSA:1.10.3720.10 39 306 8.5E-38 T 28-03-2018 CFK41_RS11380 395e2930ed3c7df74c4b8cc30b56a0aa 319 SUPERFAMILY SSF161098 111 300 1.05E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS05860 3157db1e2a73781f4cab36e73c72e1d8 475 Pfam PF01882 Protein of unknown function DUF58 281 358 2.8E-23 T 28-03-2018 IPR002881 Domain of unknown function DUF58 CFK41_RS05860 3157db1e2a73781f4cab36e73c72e1d8 475 Gene3D G3DSA:3.40.50.410 292 468 1.5E-8 T 28-03-2018 IPR002035 von Willebrand factor, type A CFK41_RS03235 c7e7ec34bd658062962905f1c15900ca 521 Gene3D G3DSA:1.20.120.450 156 388 0.0013 T 28-03-2018 CFK41_RS03235 c7e7ec34bd658062962905f1c15900ca 521 Pfam PF11855 Protein of unknown function (DUF3375) 26 514 6.4E-130 T 28-03-2018 IPR021804 Protein of unknown function DUF3375 CFK41_RS00745 31b10965697f92e586ff15a7e51d5e31 503 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 30 433 1.6E-37 T 28-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 CFK41_RS00745 31b10965697f92e586ff15a7e51d5e31 503 PIRSF PIRSF002744 1 460 2.7E-96 T 28-03-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 CFK41_RS00745 31b10965697f92e586ff15a7e51d5e31 503 PIRSF PIRSF002744 453 493 71.0 T 28-03-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 CFK41_RS07785 50645d2002b00a9f52b9d1bca832e66e 516 Hamap MF_01567 UPF0371 protein . 22 516 57.294 T 28-03-2018 IPR014999 Uncharacterised protein family UPF0371 CFK41_RS07785 50645d2002b00a9f52b9d1bca832e66e 516 Pfam PF08903 Domain of unknown function (DUF1846) 24 513 3.5E-233 T 28-03-2018 IPR014999 Uncharacterised protein family UPF0371 CFK41_RS07785 50645d2002b00a9f52b9d1bca832e66e 516 Gene3D G3DSA:3.10.630.10 23 253 1.2E-103 T 28-03-2018 CFK41_RS07785 50645d2002b00a9f52b9d1bca832e66e 516 Gene3D G3DSA:3.10.630.10 254 298 2.1E-13 T 28-03-2018 CFK41_RS07785 50645d2002b00a9f52b9d1bca832e66e 516 PIRSF PIRSF033132 22 516 7.9E-251 T 28-03-2018 IPR014999 Uncharacterised protein family UPF0371 CFK41_RS07785 50645d2002b00a9f52b9d1bca832e66e 516 Gene3D G3DSA:1.20.1570.10 299 359 3.0E-27 T 28-03-2018 CFK41_RS09165 e9ac84777aba11528aaffd77f965efd3 369 Gene3D G3DSA:1.10.3660.10 181 285 1.9E-8 T 28-03-2018 CFK41_RS09165 e9ac84777aba11528aaffd77f965efd3 369 Gene3D G3DSA:3.30.70.260 296 361 5.2E-6 T 28-03-2018 CFK41_RS09165 e9ac84777aba11528aaffd77f965efd3 369 SUPERFAMILY SSF48179 173 259 2.61E-21 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CFK41_RS09165 e9ac84777aba11528aaffd77f965efd3 369 SUPERFAMILY SSF51735 9 167 1.04E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS09165 e9ac84777aba11528aaffd77f965efd3 369 Gene3D G3DSA:3.40.50.720 9 172 4.9E-22 T 28-03-2018 CFK41_RS09165 e9ac84777aba11528aaffd77f965efd3 369 Pfam PF02153 Prephenate dehydrogenase 21 259 1.4E-46 T 28-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 CFK41_RS09165 e9ac84777aba11528aaffd77f965efd3 369 SUPERFAMILY SSF55021 300 360 2.5E-6 T 28-03-2018 CFK41_RS12850 2604bd2675f91c35ce7b8e2313a86047 404 SUPERFAMILY SSF51445 64 85 5.26E-56 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS12850 2604bd2675f91c35ce7b8e2313a86047 404 SUPERFAMILY SSF51445 115 403 5.26E-56 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS12850 2604bd2675f91c35ce7b8e2313a86047 404 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 314 331 - T 28-03-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 CFK41_RS12850 2604bd2675f91c35ce7b8e2313a86047 404 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 79 394 1.7E-46 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS12850 2604bd2675f91c35ce7b8e2313a86047 404 Gene3D G3DSA:3.20.20.300 62 404 1.7E-59 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS16110 7a0305af078b8eeefbff0f2a987a2a19 304 SUPERFAMILY SSF46785 1 111 1.09E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS16110 7a0305af078b8eeefbff0f2a987a2a19 304 SUPERFAMILY SSF53850 90 297 1.25E-36 T 28-03-2018 CFK41_RS16110 7a0305af078b8eeefbff0f2a987a2a19 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.4E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CFK41_RS16110 7a0305af078b8eeefbff0f2a987a2a19 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.4E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CFK41_RS16110 7a0305af078b8eeefbff0f2a987a2a19 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.4E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CFK41_RS16110 7a0305af078b8eeefbff0f2a987a2a19 304 Gene3D G3DSA:3.40.190.10 181 269 2.9E-20 T 28-03-2018 CFK41_RS16110 7a0305af078b8eeefbff0f2a987a2a19 304 Gene3D G3DSA:3.40.190.10 89 180 1.3E-25 T 28-03-2018 CFK41_RS16110 7a0305af078b8eeefbff0f2a987a2a19 304 Pfam PF03466 LysR substrate binding domain 89 293 6.1E-40 T 28-03-2018 IPR005119 LysR, substrate-binding CFK41_RS16110 7a0305af078b8eeefbff0f2a987a2a19 304 Gene3D G3DSA:1.10.10.10 1 86 2.9E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS16110 7a0305af078b8eeefbff0f2a987a2a19 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 1.3E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CFK41_RS05535 2e32b1f49c5025f2affe1e6315176bec 215 SUPERFAMILY SSF51735 1 199 2.12E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS05535 2e32b1f49c5025f2affe1e6315176bec 215 Gene3D G3DSA:3.40.50.720 2 215 1.2E-22 T 28-03-2018 CFK41_RS05535 2e32b1f49c5025f2affe1e6315176bec 215 Pfam PF13460 NAD(P)H-binding 7 191 1.4E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS07535 6582e4a9fa7492f27fb9e101f17e1096 381 Gene3D G3DSA:2.30.130.10 288 380 8.7E-23 T 28-03-2018 IPR002478 PUA domain GO:0003723 CFK41_RS07535 6582e4a9fa7492f27fb9e101f17e1096 381 SMART SM00359 290 373 2.0E-12 T 28-03-2018 IPR002478 PUA domain GO:0003723 CFK41_RS07535 6582e4a9fa7492f27fb9e101f17e1096 381 Hamap MF_00456 Glutamate 5-kinase [proB]. 22 275 33.063 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CFK41_RS07535 6582e4a9fa7492f27fb9e101f17e1096 381 TIGRFAM TIGR01027 proB: glutamate 5-kinase 22 379 1.7E-117 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CFK41_RS07535 6582e4a9fa7492f27fb9e101f17e1096 381 Pfam PF01472 PUA domain 290 361 7.4E-17 T 28-03-2018 IPR002478 PUA domain GO:0003723 CFK41_RS07535 6582e4a9fa7492f27fb9e101f17e1096 381 SUPERFAMILY SSF53633 22 268 4.84E-59 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CFK41_RS07535 6582e4a9fa7492f27fb9e101f17e1096 381 Pfam PF00696 Amino acid kinase family 23 244 1.0E-37 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CFK41_RS07535 6582e4a9fa7492f27fb9e101f17e1096 381 PRINTS PR00474 Glutamate 5-kinase family signature 93 121 8.3E-49 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CFK41_RS07535 6582e4a9fa7492f27fb9e101f17e1096 381 PRINTS PR00474 Glutamate 5-kinase family signature 133 154 8.3E-49 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CFK41_RS07535 6582e4a9fa7492f27fb9e101f17e1096 381 PRINTS PR00474 Glutamate 5-kinase family signature 165 192 8.3E-49 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CFK41_RS07535 6582e4a9fa7492f27fb9e101f17e1096 381 PRINTS PR00474 Glutamate 5-kinase family signature 59 73 8.3E-49 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CFK41_RS07535 6582e4a9fa7492f27fb9e101f17e1096 381 PRINTS PR00474 Glutamate 5-kinase family signature 225 245 8.3E-49 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CFK41_RS07535 6582e4a9fa7492f27fb9e101f17e1096 381 SUPERFAMILY SSF88697 290 380 7.18E-19 T 28-03-2018 IPR015947 PUA-like domain CFK41_RS07535 6582e4a9fa7492f27fb9e101f17e1096 381 ProSitePatterns PS00902 Glutamate 5-kinase signature. 223 240 - T 28-03-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CFK41_RS07535 6582e4a9fa7492f27fb9e101f17e1096 381 Gene3D G3DSA:3.40.1160.10 10 278 6.3E-56 T 28-03-2018 CFK41_RS07535 6582e4a9fa7492f27fb9e101f17e1096 381 PIRSF PIRSF000729 18 381 4.8E-114 T 28-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CFK41_RS07155 2470b6eb1308d3b0e420d40f1c2f89bb 362 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 1 359 35.52 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CFK41_RS07155 2470b6eb1308d3b0e420d40f1c2f89bb 362 Gene3D G3DSA:2.30.30.280 214 278 6.7E-18 T 28-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 CFK41_RS07155 2470b6eb1308d3b0e420d40f1c2f89bb 362 SUPERFAMILY SSF52402 1 245 2.05E-44 T 28-03-2018 CFK41_RS07155 2470b6eb1308d3b0e420d40f1c2f89bb 362 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 1 356 1.2E-84 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CFK41_RS07155 2470b6eb1308d3b0e420d40f1c2f89bb 362 Gene3D G3DSA:2.40.30.10 279 362 5.2E-15 T 28-03-2018 CFK41_RS07155 2470b6eb1308d3b0e420d40f1c2f89bb 362 Gene3D G3DSA:3.40.50.620 1 213 9.5E-53 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS07155 2470b6eb1308d3b0e420d40f1c2f89bb 362 Pfam PF03054 tRNA methyl transferase 1 357 1.5E-106 T 28-03-2018 CFK41_RS17555 a1b49b06a589577cb634ddaa4ca4b634 865 Pfam PF00912 Transglycosylase 178 347 4.1E-58 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CFK41_RS17555 a1b49b06a589577cb634ddaa4ca4b634 865 Gene3D G3DSA:3.40.710.10 366 828 1.8E-98 T 28-03-2018 CFK41_RS17555 a1b49b06a589577cb634ddaa4ca4b634 865 Gene3D G3DSA:1.10.3810.10 166 364 7.6E-69 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CFK41_RS17555 a1b49b06a589577cb634ddaa4ca4b634 865 SUPERFAMILY SSF53955 162 365 1.12E-65 T 28-03-2018 IPR023346 Lysozyme-like domain CFK41_RS17555 a1b49b06a589577cb634ddaa4ca4b634 865 Pfam PF00905 Penicillin binding protein transpeptidase domain 439 690 8.6E-33 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CFK41_RS17555 a1b49b06a589577cb634ddaa4ca4b634 865 SUPERFAMILY SSF56601 381 746 3.27E-87 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CFK41_RS17555 a1b49b06a589577cb634ddaa4ca4b634 865 SUPERFAMILY SSF56601 330 352 3.27E-87 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CFK41_RS09390 1be79ce297bfb786e594478a8dc6ec8b 453 PIRSF PIRSF006060 2 445 2.3E-76 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CFK41_RS09390 1be79ce297bfb786e594478a8dc6ec8b 453 Pfam PF13520 Amino acid permease 19 402 1.1E-45 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CFK41_RS06205 40d2864ac36b0156423ef38b6d625108 154 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 36 138 1.2E-19 T 28-03-2018 IPR019277 Protein of unknown function DUF2304 CFK41_RS07720 e08214b5d983e573e34063034178fe02 318 SUPERFAMILY SSF161098 31 317 8.18E-51 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS07720 e08214b5d983e573e34063034178fe02 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 309 4.5E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS07720 e08214b5d983e573e34063034178fe02 318 Gene3D G3DSA:1.10.3720.10 88 312 9.3E-32 T 28-03-2018 CFK41_RS08175 fc0b26a05c5fa8660fb13b2f3a433add 124 Gene3D G3DSA:3.30.428.10 3 118 1.2E-32 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CFK41_RS08175 fc0b26a05c5fa8660fb13b2f3a433add 124 Pfam PF01230 HIT domain 25 116 1.1E-20 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CFK41_RS08175 fc0b26a05c5fa8660fb13b2f3a433add 124 PRINTS PR00332 Histidine triad family signature 104 114 2.3E-17 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CFK41_RS08175 fc0b26a05c5fa8660fb13b2f3a433add 124 PRINTS PR00332 Histidine triad family signature 18 34 2.3E-17 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CFK41_RS08175 fc0b26a05c5fa8660fb13b2f3a433add 124 PRINTS PR00332 Histidine triad family signature 39 57 2.3E-17 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CFK41_RS08175 fc0b26a05c5fa8660fb13b2f3a433add 124 SUPERFAMILY SSF54197 7 116 5.25E-32 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CFK41_RS17035 a8f6a18c7815629ba3d75087f91ba862 304 SUPERFAMILY SSF51735 22 179 2.92E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS17035 a8f6a18c7815629ba3d75087f91ba862 304 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 23 178 9.5E-40 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CFK41_RS17035 a8f6a18c7815629ba3d75087f91ba862 304 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 181 300 7.2E-24 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CFK41_RS17035 a8f6a18c7815629ba3d75087f91ba862 304 SUPERFAMILY SSF48179 179 301 1.25E-28 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CFK41_RS17035 a8f6a18c7815629ba3d75087f91ba862 304 PIRSF PIRSF000103 16 304 3.3E-66 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CFK41_RS17035 a8f6a18c7815629ba3d75087f91ba862 304 Gene3D G3DSA:1.10.1040.10 189 304 1.2E-24 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CFK41_RS17035 a8f6a18c7815629ba3d75087f91ba862 304 Gene3D G3DSA:3.40.50.720 11 188 1.8E-33 T 28-03-2018 CFK41_RS07900 c344bfcbb68c08f7c188b0826effbbee 277 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS07900 c344bfcbb68c08f7c188b0826effbbee 277 SMART SM00382 49 241 3.4E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS07900 c344bfcbb68c08f7c188b0826effbbee 277 Gene3D G3DSA:3.40.50.300 17 276 6.2E-70 T 28-03-2018 CFK41_RS07900 c344bfcbb68c08f7c188b0826effbbee 277 SUPERFAMILY SSF52540 20 263 1.2E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS07900 c344bfcbb68c08f7c188b0826effbbee 277 Pfam PF00005 ABC transporter 41 192 1.5E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS15990 022f3242a3f8ae4f23050dd5ce653df5 136 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 5 131 3.0E-8 T 28-03-2018 IPR028973 PhnB-like CFK41_RS15990 022f3242a3f8ae4f23050dd5ce653df5 136 SUPERFAMILY SSF54593 4 135 2.9E-27 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS15990 022f3242a3f8ae4f23050dd5ce653df5 136 Gene3D G3DSA:3.10.180.10 1 136 3.1E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS05545 0432a3531dd9852098c5910a42ec0f10 104 Pfam PF00708 Acylphosphatase 21 102 2.7E-22 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CFK41_RS05545 0432a3531dd9852098c5910a42ec0f10 104 PRINTS PR00112 Acylphosphatase signature 18 33 8.9E-5 T 28-03-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CFK41_RS05545 0432a3531dd9852098c5910a42ec0f10 104 PRINTS PR00112 Acylphosphatase signature 39 64 8.9E-5 T 28-03-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CFK41_RS05545 0432a3531dd9852098c5910a42ec0f10 104 SUPERFAMILY SSF54975 15 102 1.53E-24 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CFK41_RS05545 0432a3531dd9852098c5910a42ec0f10 104 ProSitePatterns PS00150 Acylphosphatase signature 1. 23 33 - T 28-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CFK41_RS05545 0432a3531dd9852098c5910a42ec0f10 104 Gene3D G3DSA:3.30.70.100 8 104 1.6E-24 T 28-03-2018 CFK41_RS01835 e9d509a3203ecc2eba4bae9379cbd470 410 SUPERFAMILY SSF51569 152 351 1.78E-13 T 28-03-2018 CFK41_RS01835 e9d509a3203ecc2eba4bae9379cbd470 410 Gene3D G3DSA:3.20.20.70 42 374 7.2E-61 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS01835 e9d509a3203ecc2eba4bae9379cbd470 410 Pfam PF06187 Protein of unknown function (DUF993) 7 402 2.0E-161 T 28-03-2018 IPR009334 Protein of unknown function DUF993 CFK41_RS04965 3630e41a392aa1593da20a8fa9787b0e 130 Pfam PF14155 Domain of unknown function (DUF4307) 19 127 1.0E-23 T 28-03-2018 IPR025443 Protein of unknown function DUF4307 CFK41_RS12725 570b32b4f9a0391e634a1281dfd730d2 414 Pfam PF01882 Protein of unknown function DUF58 166 253 3.0E-15 T 28-03-2018 IPR002881 Domain of unknown function DUF58 CFK41_RS12725 570b32b4f9a0391e634a1281dfd730d2 414 Gene3D G3DSA:3.40.50.410 176 310 8.3E-8 T 28-03-2018 IPR002035 von Willebrand factor, type A CFK41_RS00165 ff2a47de469cf6fa11c634ccf661af4b 373 Gene3D G3DSA:1.25.40.290 133 245 9.4E-21 T 28-03-2018 CFK41_RS00165 ff2a47de469cf6fa11c634ccf661af4b 373 Pfam PF08713 DNA alkylation repair enzyme 126 238 2.6E-5 T 28-03-2018 IPR014825 DNA alkylation repair enzyme CFK41_RS00165 ff2a47de469cf6fa11c634ccf661af4b 373 SUPERFAMILY SSF48371 50 242 3.07E-30 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CFK41_RS00165 ff2a47de469cf6fa11c634ccf661af4b 373 Gene3D G3DSA:2.60.40.10 259 355 4.8E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS12750 b8015d910ea01621756d701a62563f98 172 Pfam PF06953 Arsenical resistance operon trans-acting repressor ArsD 35 117 4.5E-8 T 28-03-2018 IPR010712 Arsenical-resistance operon trans-acting repressor ArsD GO:0003677|GO:0045892|GO:0046685 CFK41_RS03330 88d8ba8552a5357ead6f93eed80804cf 416 Gene3D G3DSA:3.40.50.720 38 396 0.0044 T 28-03-2018 CFK41_RS03330 88d8ba8552a5357ead6f93eed80804cf 416 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 208 320 1.2E-7 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 CFK41_RS02605 dc0e0d3a11927d63c77d79d7e24e72f3 204 Gene3D G3DSA:1.10.260.40 44 73 2.0E-9 T 28-03-2018 CFK41_RS02605 dc0e0d3a11927d63c77d79d7e24e72f3 204 SUPERFAMILY SSF48498 94 199 2.78E-11 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CFK41_RS02605 dc0e0d3a11927d63c77d79d7e24e72f3 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 1.8E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS02605 dc0e0d3a11927d63c77d79d7e24e72f3 204 Gene3D G3DSA:1.10.357.10 74 203 1.0E-19 T 28-03-2018 CFK41_RS02605 dc0e0d3a11927d63c77d79d7e24e72f3 204 Pfam PF13305 WHG domain 96 177 3.8E-13 T 28-03-2018 IPR025996 WHG domain CFK41_RS02605 dc0e0d3a11927d63c77d79d7e24e72f3 204 SUPERFAMILY SSF46689 11 85 1.08E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS02605 dc0e0d3a11927d63c77d79d7e24e72f3 204 Gene3D G3DSA:1.10.10.60 1 43 2.9E-10 T 28-03-2018 CFK41_RS15635 35d9bd8f84a4004bb69942a2718f9a54 1048 Pfam PF12419 SNF2 Helicase protein 315 428 1.8E-30 T 28-03-2018 IPR022138 Helicase SWF/SNF-related CFK41_RS15635 35d9bd8f84a4004bb69942a2718f9a54 1048 Pfam PF00271 Helicase conserved C-terminal domain 868 985 8.9E-14 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS15635 35d9bd8f84a4004bb69942a2718f9a54 1048 Gene3D G3DSA:3.40.50.10810 530 794 2.0E-52 T 28-03-2018 CFK41_RS15635 35d9bd8f84a4004bb69942a2718f9a54 1048 SMART SM00490 901 985 4.6E-19 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS15635 35d9bd8f84a4004bb69942a2718f9a54 1048 Gene3D G3DSA:3.40.50.300 862 1023 1.5E-28 T 28-03-2018 CFK41_RS15635 35d9bd8f84a4004bb69942a2718f9a54 1048 Pfam PF00176 SNF2 family N-terminal domain 556 849 3.1E-58 T 28-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 CFK41_RS15635 35d9bd8f84a4004bb69942a2718f9a54 1048 SUPERFAMILY SSF52540 783 1044 1.04E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS15635 35d9bd8f84a4004bb69942a2718f9a54 1048 SUPERFAMILY SSF52540 528 780 1.53E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS15635 35d9bd8f84a4004bb69942a2718f9a54 1048 SMART SM00487 538 752 2.4E-26 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CFK41_RS03440 00fcaa1f0a38552ba7db8faff85dbdc3 358 Gene3D G3DSA:3.40.50.720 25 162 1.1E-32 T 28-03-2018 CFK41_RS03440 00fcaa1f0a38552ba7db8faff85dbdc3 358 SUPERFAMILY SSF55347 156 319 1.18E-33 T 28-03-2018 CFK41_RS03440 00fcaa1f0a38552ba7db8faff85dbdc3 358 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 33 145 7.0E-18 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS03440 00fcaa1f0a38552ba7db8faff85dbdc3 358 Gene3D G3DSA:3.30.360.10 163 357 5.9E-32 T 28-03-2018 CFK41_RS03440 00fcaa1f0a38552ba7db8faff85dbdc3 358 SUPERFAMILY SSF51735 29 182 1.86E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS01415 4342538d3118ab16cccf79a9a0e437ba 288 Gene3D G3DSA:1.10.3720.10 65 282 2.1E-31 T 28-03-2018 CFK41_RS01415 4342538d3118ab16cccf79a9a0e437ba 288 SUPERFAMILY SSF161098 6 288 1.74E-50 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01415 4342538d3118ab16cccf79a9a0e437ba 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 281 1.5E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS02830 c783d8a78ec380fefeefe8e16adcd7a8 1022 SUPERFAMILY SSF52540 2 97 2.42E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS02830 c783d8a78ec380fefeefe8e16adcd7a8 1022 SUPERFAMILY SSF52540 133 237 2.42E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS02830 c783d8a78ec380fefeefe8e16adcd7a8 1022 SUPERFAMILY SSF52540 869 1010 2.42E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS02830 c783d8a78ec380fefeefe8e16adcd7a8 1022 Gene3D G3DSA:3.40.50.300 1 210 2.2E-20 T 28-03-2018 CFK41_RS02830 c783d8a78ec380fefeefe8e16adcd7a8 1022 Gene3D G3DSA:3.40.50.300 858 1012 3.8E-13 T 28-03-2018 CFK41_RS02830 c783d8a78ec380fefeefe8e16adcd7a8 1022 Pfam PF13476 AAA domain 6 225 4.2E-21 T 28-03-2018 CFK41_RS02830 c783d8a78ec380fefeefe8e16adcd7a8 1022 Pfam PF13558 Putative exonuclease SbcCD, C subunit 917 976 1.6E-10 T 28-03-2018 CFK41_RS04815 067a97a3cd949dc548038b9375673fc0 369 SUPERFAMILY SSF56601 7 348 1.62E-65 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CFK41_RS04815 067a97a3cd949dc548038b9375673fc0 369 Gene3D G3DSA:3.40.710.10 2 366 4.7E-65 T 28-03-2018 CFK41_RS04815 067a97a3cd949dc548038b9375673fc0 369 Pfam PF00144 Beta-lactamase 9 347 2.1E-53 T 28-03-2018 IPR001466 Beta-lactamase-related CFK41_RS03885 b0dfa6d2177ce49c0106295a160c59ea 370 Gene3D G3DSA:3.30.565.10 161 367 1.6E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS03885 b0dfa6d2177ce49c0106295a160c59ea 370 Pfam PF07730 Histidine kinase 167 231 5.9E-16 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CFK41_RS14240 f478e952c072f1ed02520db43bfee745 433 Gene3D G3DSA:3.40.190.10 183 372 0.0013 T 28-03-2018 CFK41_RS14240 f478e952c072f1ed02520db43bfee745 433 Pfam PF13416 Bacterial extracellular solute-binding protein 63 354 4.0E-18 T 28-03-2018 CFK41_RS14240 f478e952c072f1ed02520db43bfee745 433 Gene3D G3DSA:3.40.190.10 25 182 5.4E-21 T 28-03-2018 CFK41_RS14240 f478e952c072f1ed02520db43bfee745 433 SUPERFAMILY SSF53850 36 421 4.22E-39 T 28-03-2018 CFK41_RS09125 1713994a35a30d703c7b1a0f141bc386 297 SUPERFAMILY SSF161098 28 291 9.0E-58 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS09125 1713994a35a30d703c7b1a0f141bc386 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 282 1.6E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS09125 1713994a35a30d703c7b1a0f141bc386 297 Gene3D G3DSA:1.10.3720.10 19 283 5.1E-38 T 28-03-2018 CFK41_RS08950 05d2a864ccde9ff98de2f6cccd942423 271 Pfam PF01841 Transglutaminase-like superfamily 125 213 8.5E-19 T 28-03-2018 IPR002931 Transglutaminase-like CFK41_RS08950 05d2a864ccde9ff98de2f6cccd942423 271 SMART SM00460 155 215 8.4E-12 T 28-03-2018 IPR002931 Transglutaminase-like CFK41_RS08950 05d2a864ccde9ff98de2f6cccd942423 271 SUPERFAMILY SSF54001 100 237 8.27E-27 T 28-03-2018 CFK41_RS08950 05d2a864ccde9ff98de2f6cccd942423 271 Gene3D G3DSA:3.90.260.10 136 207 2.9E-6 T 28-03-2018 IPR002931 Transglutaminase-like CFK41_RS05690 ad0c75e61500f1b9cb0b95aecf83c106 64 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 17.063 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CFK41_RS05690 ad0c75e61500f1b9cb0b95aecf83c106 64 Pfam PF01632 Ribosomal protein L35 2 62 6.9E-24 T 28-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS05690 ad0c75e61500f1b9cb0b95aecf83c106 64 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 7.0E-23 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CFK41_RS05690 ad0c75e61500f1b9cb0b95aecf83c106 64 PRINTS PR00064 Ribosomal protein L35 signature 3 20 4.6E-16 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CFK41_RS05690 ad0c75e61500f1b9cb0b95aecf83c106 64 PRINTS PR00064 Ribosomal protein L35 signature 36 54 4.6E-16 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CFK41_RS05690 ad0c75e61500f1b9cb0b95aecf83c106 64 PRINTS PR00064 Ribosomal protein L35 signature 21 35 4.6E-16 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CFK41_RS05690 ad0c75e61500f1b9cb0b95aecf83c106 64 SUPERFAMILY SSF143034 2 63 6.41E-21 T 28-03-2018 CFK41_RS00570 2929b50d9853e7f27b03a41aa6a19d4e 346 SUPERFAMILY SSF161098 106 332 7.72E-61 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS00570 2929b50d9853e7f27b03a41aa6a19d4e 346 Gene3D G3DSA:1.20.58.370 54 95 7.9E-5 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CFK41_RS00570 2929b50d9853e7f27b03a41aa6a19d4e 346 Gene3D G3DSA:1.10.3720.10 113 343 4.6E-50 T 28-03-2018 CFK41_RS00570 2929b50d9853e7f27b03a41aa6a19d4e 346 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 140 341 1.8E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS00275 561e770f7f026b0448ffe8b30d211a89 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 9.6E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS00275 561e770f7f026b0448ffe8b30d211a89 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 9.6E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS00275 561e770f7f026b0448ffe8b30d211a89 191 SUPERFAMILY SSF46689 2 85 1.49E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS00275 561e770f7f026b0448ffe8b30d211a89 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 9.2E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS00275 561e770f7f026b0448ffe8b30d211a89 191 Gene3D G3DSA:1.10.10.60 49 141 6.7E-12 T 28-03-2018 CFK41_RS00275 561e770f7f026b0448ffe8b30d211a89 191 Gene3D G3DSA:1.10.10.60 1 48 1.1E-16 T 28-03-2018 CFK41_RS13840 8135696862289cf851e2e7b4d590b28d 490 Gene3D G3DSA:3.40.720.10 321 389 2.0E-10 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CFK41_RS13840 8135696862289cf851e2e7b4d590b28d 490 Gene3D G3DSA:3.40.720.10 4 320 5.4E-69 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CFK41_RS13840 8135696862289cf851e2e7b4d590b28d 490 Gene3D G3DSA:3.30.1120.10 390 464 1.7E-10 T 28-03-2018 CFK41_RS13840 8135696862289cf851e2e7b4d590b28d 490 SUPERFAMILY SSF53649 177 457 1.18E-103 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CFK41_RS13840 8135696862289cf851e2e7b4d590b28d 490 SUPERFAMILY SSF53649 5 134 1.18E-103 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CFK41_RS13840 8135696862289cf851e2e7b4d590b28d 490 Pfam PF00884 Sulfatase 7 368 1.8E-58 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CFK41_RS17650 2de3589029dd55965e2e02e06ee90d90 374 Gene3D G3DSA:3.30.420.40 77 188 9.2E-24 T 28-03-2018 CFK41_RS17650 2de3589029dd55965e2e02e06ee90d90 374 Gene3D G3DSA:3.30.420.40 239 358 5.4E-18 T 28-03-2018 CFK41_RS17650 2de3589029dd55965e2e02e06ee90d90 374 Pfam PF00480 ROK family 254 347 3.0E-9 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CFK41_RS17650 2de3589029dd55965e2e02e06ee90d90 374 Pfam PF00480 ROK family 87 232 1.2E-17 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CFK41_RS17650 2de3589029dd55965e2e02e06ee90d90 374 Gene3D G3DSA:1.10.10.10 9 76 1.1E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS17650 2de3589029dd55965e2e02e06ee90d90 374 SUPERFAMILY SSF46785 15 79 1.18E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS17650 2de3589029dd55965e2e02e06ee90d90 374 SUPERFAMILY SSF53067 87 348 3.4E-33 T 28-03-2018 CFK41_RS17650 2de3589029dd55965e2e02e06ee90d90 374 Gene3D G3DSA:3.40.367.20 189 238 2.0E-11 T 28-03-2018 CFK41_RS17650 2de3589029dd55965e2e02e06ee90d90 374 Pfam PF09339 IclR helix-turn-helix domain 23 60 4.2E-6 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CFK41_RS00620 9c21bcf05e736a545f0012a96c4e07cf 262 Pfam PF03881 Fructosamine kinase 4 250 3.1E-31 T 28-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 CFK41_RS00620 9c21bcf05e736a545f0012a96c4e07cf 262 SUPERFAMILY SSF56112 13 244 7.73E-30 T 28-03-2018 IPR011009 Protein kinase-like domain CFK41_RS00620 9c21bcf05e736a545f0012a96c4e07cf 262 Gene3D G3DSA:3.90.1200.10 47 250 5.1E-20 T 28-03-2018 CFK41_RS00620 9c21bcf05e736a545f0012a96c4e07cf 262 Gene3D G3DSA:3.30.200.20 2 46 1.0E-7 T 28-03-2018 CFK41_RS00620 9c21bcf05e736a545f0012a96c4e07cf 262 PIRSF PIRSF006221 1 258 4.3E-47 T 28-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 CFK41_RS16100 8c5d60add29a06a34d9e4768ab223362 446 Pfam PF00296 Luciferase-like monooxygenase 48 396 2.5E-51 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CFK41_RS16100 8c5d60add29a06a34d9e4768ab223362 446 PIRSF PIRSF000337 24 446 4.2E-111 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CFK41_RS16100 8c5d60add29a06a34d9e4768ab223362 446 SUPERFAMILY SSF51679 26 444 9.03E-98 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CFK41_RS16100 8c5d60add29a06a34d9e4768ab223362 446 Gene3D G3DSA:3.20.20.30 19 446 1.3E-86 T 28-03-2018 CFK41_RS13635 958b2dd75f502af1be7a1fe045d0fd09 301 SUPERFAMILY SSF53474 40 269 5.57E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS13635 958b2dd75f502af1be7a1fe045d0fd09 301 Gene3D G3DSA:3.40.50.1820 6 299 1.2E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS13635 958b2dd75f502af1be7a1fe045d0fd09 301 Pfam PF07859 alpha/beta hydrolase fold 70 267 1.6E-31 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CFK41_RS12905 93544845e9fb793c88aa33ab14bdf920 719 Gene3D G3DSA:1.10.10.10 3 449 0.012 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS12905 93544845e9fb793c88aa33ab14bdf920 719 Pfam PF13625 Helicase conserved C-terminal domain 456 576 7.4E-24 T 28-03-2018 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 CFK41_RS01585 101e18f50583e7fe840baec2d1edfaec 383 Gene3D G3DSA:3.40.50.2300 148 378 1.7E-26 T 28-03-2018 CFK41_RS01585 101e18f50583e7fe840baec2d1edfaec 383 SUPERFAMILY SSF53822 42 366 2.21E-62 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS01585 101e18f50583e7fe840baec2d1edfaec 383 Pfam PF13407 Periplasmic binding protein domain 44 332 6.9E-60 T 28-03-2018 IPR025997 Periplasmic binding protein CFK41_RS01585 101e18f50583e7fe840baec2d1edfaec 383 Gene3D G3DSA:3.40.50.2300 42 147 1.7E-17 T 28-03-2018 CFK41_RS16615 49036cde2cbff76bfbae799186db1df2 322 Pfam PF13280 WYL domain 140 310 3.2E-33 T 28-03-2018 IPR026881 WYL domain CFK41_RS16615 49036cde2cbff76bfbae799186db1df2 322 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CFK41_RS16615 49036cde2cbff76bfbae799186db1df2 322 PIRSF PIRSF016838 1 318 1.1E-26 T 28-03-2018 IPR028349 Protein PafC CFK41_RS16615 49036cde2cbff76bfbae799186db1df2 322 Pfam PF08279 HTH domain 7 62 9.8E-13 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CFK41_RS16615 49036cde2cbff76bfbae799186db1df2 322 Gene3D G3DSA:1.10.10.10 3 65 1.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS16615 49036cde2cbff76bfbae799186db1df2 322 SUPERFAMILY SSF46785 6 62 2.01E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS11925 2983d99ec3c8455c686a35ba127cade0 452 Pfam PF01566 Natural resistance-associated macrophage protein 57 421 4.6E-37 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CFK41_RS17170 1fc03f1ce57b2779e0d6437df0707059 420 Pfam PF00326 Prolyl oligopeptidase family 264 324 4.7E-7 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CFK41_RS17170 1fc03f1ce57b2779e0d6437df0707059 420 SUPERFAMILY SSF53474 170 382 6.95E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS17170 1fc03f1ce57b2779e0d6437df0707059 420 Gene3D G3DSA:3.40.50.1820 173 420 1.7E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS01990 e61c6f8743bb81d2f99f732c9153ae07 374 Pfam PF01758 Sodium Bile acid symporter family 62 258 8.5E-58 T 28-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 CFK41_RS01990 e61c6f8743bb81d2f99f732c9153ae07 374 PIRSF PIRSF005508 4 362 2.0E-138 T 28-03-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 CFK41_RS01990 e61c6f8743bb81d2f99f732c9153ae07 374 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 17 345 3.3E-130 T 28-03-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 CFK41_RS13605 8543a0e300cbf4f255a851a57e923611 456 Gene3D G3DSA:3.30.559.10 4 175 3.0E-4 T 28-03-2018 CFK41_RS13605 8543a0e300cbf4f255a851a57e923611 456 SUPERFAMILY SSF52777 30 143 1.56E-5 T 28-03-2018 CFK41_RS02245 c91ed02fd52bc74a7c73382c00aaada3 427 Gene3D G3DSA:3.40.50.2000 4 238 1.1E-13 T 28-03-2018 CFK41_RS02245 c91ed02fd52bc74a7c73382c00aaada3 427 Gene3D G3DSA:3.40.50.2000 239 407 3.1E-22 T 28-03-2018 CFK41_RS02245 c91ed02fd52bc74a7c73382c00aaada3 427 SUPERFAMILY SSF53756 2 425 5.14E-36 T 28-03-2018 CFK41_RS02245 c91ed02fd52bc74a7c73382c00aaada3 427 Pfam PF13692 Glycosyl transferases group 1 247 389 1.8E-9 T 28-03-2018 CFK41_RS02245 c91ed02fd52bc74a7c73382c00aaada3 427 Pfam PF13579 Glycosyl transferase 4-like domain 18 226 7.0E-11 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CFK41_RS16830 a83bad11e91a03f963cf6938660334f9 183 SUPERFAMILY SSF53597 3 180 1.44E-24 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CFK41_RS16830 a83bad11e91a03f963cf6938660334f9 183 Pfam PF01872 RibD C-terminal domain 4 174 7.8E-21 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CFK41_RS16830 a83bad11e91a03f963cf6938660334f9 183 Gene3D G3DSA:3.40.430.10 3 180 1.1E-29 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CFK41_RS00630 8cd8df9c601b5c3f7e9d1d5496509ee1 306 Pfam PF01925 Sulfite exporter TauE/SafE 8 298 8.9E-55 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CFK41_RS11385 1aa845af569123eac9a9c9d4d65114a2 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 307 3.8E-33 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS11385 1aa845af569123eac9a9c9d4d65114a2 309 SUPERFAMILY SSF161098 90 289 1.18E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS11385 1aa845af569123eac9a9c9d4d65114a2 309 Gene3D G3DSA:1.10.3720.10 4 295 1.2E-37 T 28-03-2018 CFK41_RS16620 88ef93a783b7808a6560474ed1d33ffd 271 Pfam PF01925 Sulfite exporter TauE/SafE 20 267 7.1E-29 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CFK41_RS04735 dd093f9655008e459972e14e3b9e93a2 718 Gene3D G3DSA:3.40.80.10 228 432 7.4E-41 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CFK41_RS04735 dd093f9655008e459972e14e3b9e93a2 718 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 263 413 3.1E-15 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CFK41_RS04735 dd093f9655008e459972e14e3b9e93a2 718 Pfam PF00395 S-layer homology domain 597 643 2.9E-8 T 28-03-2018 IPR001119 S-layer homology domain CFK41_RS04735 dd093f9655008e459972e14e3b9e93a2 718 Pfam PF00395 S-layer homology domain 663 705 1.7E-11 T 28-03-2018 IPR001119 S-layer homology domain CFK41_RS04735 dd093f9655008e459972e14e3b9e93a2 718 SMART SM00701 238 382 1.5E-38 T 28-03-2018 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CFK41_RS04735 dd093f9655008e459972e14e3b9e93a2 718 SUPERFAMILY SSF55846 238 424 1.57E-44 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CFK41_RS04735 dd093f9655008e459972e14e3b9e93a2 718 SMART SM00644 251 413 0.0029 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CFK41_RS12700 58bdbc6f3c9d19328d357b3896cb81f7 328 SUPERFAMILY SSF50129 1 166 5.33E-24 T 28-03-2018 IPR011032 GroES-like CFK41_RS12700 58bdbc6f3c9d19328d357b3896cb81f7 328 Gene3D G3DSA:3.40.50.720 159 257 4.2E-19 T 28-03-2018 CFK41_RS12700 58bdbc6f3c9d19328d357b3896cb81f7 328 SMART SM00829 10 324 2.6E-13 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CFK41_RS12700 58bdbc6f3c9d19328d357b3896cb81f7 328 Gene3D G3DSA:3.90.180.10 258 328 5.5E-7 T 28-03-2018 CFK41_RS12700 58bdbc6f3c9d19328d357b3896cb81f7 328 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 89 1.4E-4 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CFK41_RS12700 58bdbc6f3c9d19328d357b3896cb81f7 328 Gene3D G3DSA:3.90.180.10 1 158 2.0E-33 T 28-03-2018 CFK41_RS12700 58bdbc6f3c9d19328d357b3896cb81f7 328 SUPERFAMILY SSF51735 131 262 1.83E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS12700 58bdbc6f3c9d19328d357b3896cb81f7 328 Pfam PF13602 Zinc-binding dehydrogenase 200 324 1.4E-21 T 28-03-2018 CFK41_RS08635 4ccd9fbc5fec55f16c0f1ce1a2254098 372 Pfam PF13398 Peptidase M50B-like 53 125 3.6E-5 T 28-03-2018 CFK41_RS09105 93a3e9e451700e913d7241433cbfc197 737 SUPERFAMILY SSF82866 130 354 9.55E-36 T 28-03-2018 CFK41_RS09105 93a3e9e451700e913d7241433cbfc197 737 Gene3D G3DSA:1.20.1640.10 131 351 1.9E-31 T 28-03-2018 CFK41_RS09105 93a3e9e451700e913d7241433cbfc197 737 Pfam PF03176 MMPL family 433 730 1.5E-55 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CFK41_RS09105 93a3e9e451700e913d7241433cbfc197 737 Pfam PF03176 MMPL family 70 391 4.0E-60 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CFK41_RS09105 93a3e9e451700e913d7241433cbfc197 737 SUPERFAMILY SSF82866 517 728 2.09E-30 T 28-03-2018 CFK41_RS09105 93a3e9e451700e913d7241433cbfc197 737 Gene3D G3DSA:1.20.1640.10 512 726 1.6E-29 T 28-03-2018 CFK41_RS12775 a906217dd672b8c1c81389a8d44414f1 676 Pfam PF00005 ABC transporter 380 529 2.9E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS12775 a906217dd672b8c1c81389a8d44414f1 676 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 581 637 4.9E-8 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CFK41_RS12775 a906217dd672b8c1c81389a8d44414f1 676 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 276 1.5E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS12775 a906217dd672b8c1c81389a8d44414f1 676 SUPERFAMILY SSF52540 360 600 5.87E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS12775 a906217dd672b8c1c81389a8d44414f1 676 SMART SM00382 389 579 1.2E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS12775 a906217dd672b8c1c81389a8d44414f1 676 Gene3D G3DSA:1.10.3720.10 22 276 6.6E-33 T 28-03-2018 CFK41_RS12775 a906217dd672b8c1c81389a8d44414f1 676 Gene3D G3DSA:3.40.50.300 357 667 7.2E-71 T 28-03-2018 CFK41_RS12775 a906217dd672b8c1c81389a8d44414f1 676 ProSitePatterns PS00211 ABC transporters family signature. 502 516 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS12775 a906217dd672b8c1c81389a8d44414f1 676 SUPERFAMILY SSF161098 80 273 2.13E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01495 f0e5fa0c3a82819c297fa6b17ac98703 303 Gene3D G3DSA:1.10.3720.10 74 298 9.1E-29 T 28-03-2018 CFK41_RS01495 f0e5fa0c3a82819c297fa6b17ac98703 303 SUPERFAMILY SSF161098 17 303 3.53E-44 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01495 f0e5fa0c3a82819c297fa6b17ac98703 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 296 1.0E-9 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS02880 6113f1d9e1e96236573fed74af692126 310 Gene3D G3DSA:3.40.190.10 17 183 6.0E-23 T 28-03-2018 CFK41_RS02880 6113f1d9e1e96236573fed74af692126 310 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 75 296 2.1E-38 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CFK41_RS02880 6113f1d9e1e96236573fed74af692126 310 Gene3D G3DSA:3.40.190.10 184 301 4.7E-10 T 28-03-2018 CFK41_RS02880 6113f1d9e1e96236573fed74af692126 310 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 95 108 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CFK41_RS02880 6113f1d9e1e96236573fed74af692126 310 SMART SM00062 72 298 9.8E-22 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CFK41_RS02880 6113f1d9e1e96236573fed74af692126 310 SUPERFAMILY SSF53850 19 32 8.1E-40 T 28-03-2018 CFK41_RS02880 6113f1d9e1e96236573fed74af692126 310 SUPERFAMILY SSF53850 62 295 8.1E-40 T 28-03-2018 CFK41_RS01005 0487d7d5a2c2677517bf2e6830ab37c8 492 SUPERFAMILY SSF53474 289 403 7.34E-8 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS01005 0487d7d5a2c2677517bf2e6830ab37c8 492 Gene3D G3DSA:3.40.50.1820 275 452 1.5E-6 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS01005 0487d7d5a2c2677517bf2e6830ab37c8 492 Gene3D G3DSA:1.10.287.850 1 91 2.7E-4 T 28-03-2018 CFK41_RS15540 85f0f6c501bc284b89e1d8ce71e774e3 703 Gene3D G3DSA:3.40.50.1820 1 107 3.8E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS15540 85f0f6c501bc284b89e1d8ce71e774e3 703 Gene3D G3DSA:3.40.50.1820 390 703 1.4E-51 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS15540 85f0f6c501bc284b89e1d8ce71e774e3 703 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 524 554 - T 28-03-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 CFK41_RS15540 85f0f6c501bc284b89e1d8ce71e774e3 703 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 10 420 2.4E-83 T 28-03-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 CFK41_RS15540 85f0f6c501bc284b89e1d8ce71e774e3 703 SUPERFAMILY SSF50993 5 424 3.4E-78 T 28-03-2018 CFK41_RS15540 85f0f6c501bc284b89e1d8ce71e774e3 703 Gene3D G3DSA:2.120.10.30 108 389 4.7E-7 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CFK41_RS15540 85f0f6c501bc284b89e1d8ce71e774e3 703 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 463 481 3.5E-49 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CFK41_RS15540 85f0f6c501bc284b89e1d8ce71e774e3 703 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 489 513 3.5E-49 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CFK41_RS15540 85f0f6c501bc284b89e1d8ce71e774e3 703 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 517 536 3.5E-49 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CFK41_RS15540 85f0f6c501bc284b89e1d8ce71e774e3 703 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 547 567 3.5E-49 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CFK41_RS15540 85f0f6c501bc284b89e1d8ce71e774e3 703 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 606 621 3.5E-49 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CFK41_RS15540 85f0f6c501bc284b89e1d8ce71e774e3 703 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 624 646 3.5E-49 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CFK41_RS15540 85f0f6c501bc284b89e1d8ce71e774e3 703 Pfam PF00326 Prolyl oligopeptidase family 479 698 5.2E-58 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CFK41_RS15540 85f0f6c501bc284b89e1d8ce71e774e3 703 SUPERFAMILY SSF53474 434 697 1.96E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS16965 634e7fa81e6c34fa9a22d1014718bc56 556 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 89 473 1.7E-68 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CFK41_RS16965 634e7fa81e6c34fa9a22d1014718bc56 556 Gene3D G3DSA:3.40.190.10 183 325 1.5E-31 T 28-03-2018 CFK41_RS16965 634e7fa81e6c34fa9a22d1014718bc56 556 PIRSF PIRSF002741 11 550 1.3E-69 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CFK41_RS16965 634e7fa81e6c34fa9a22d1014718bc56 556 Gene3D G3DSA:3.10.105.10 326 527 8.5E-48 T 28-03-2018 CFK41_RS16965 634e7fa81e6c34fa9a22d1014718bc56 556 Gene3D G3DSA:3.90.76.10 71 182 3.2E-20 T 28-03-2018 CFK41_RS16965 634e7fa81e6c34fa9a22d1014718bc56 556 SUPERFAMILY SSF53850 44 548 7.06E-99 T 28-03-2018 CFK41_RS05675 a10f62689cd999a4a5eaa4d87dfac573 126 Gene3D G3DSA:1.20.1410.10 4 119 7.3E-4 T 28-03-2018 CFK41_RS13875 6b364fffa1548b46b9972d1600c0d7d7 326 SUPERFAMILY SSF52768 18 316 5.04E-95 T 28-03-2018 CFK41_RS13875 6b364fffa1548b46b9972d1600c0d7d7 326 Gene3D G3DSA:3.40.800.10 12 322 2.1E-104 T 28-03-2018 CFK41_RS13875 6b364fffa1548b46b9972d1600c0d7d7 326 Pfam PF00491 Arginase family 39 312 1.8E-89 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CFK41_RS13875 6b364fffa1548b46b9972d1600c0d7d7 326 PRINTS PR00116 Arginase signature 241 270 3.7E-14 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CFK41_RS13875 6b364fffa1548b46b9972d1600c0d7d7 326 PRINTS PR00116 Arginase signature 128 143 3.7E-14 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CFK41_RS13875 6b364fffa1548b46b9972d1600c0d7d7 326 TIGRFAM TIGR01230 agmatinase: agmatinase 35 314 1.5E-66 T 28-03-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 CFK41_RS13875 6b364fffa1548b46b9972d1600c0d7d7 326 PIRSF PIRSF036979 18 320 8.5E-103 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CFK41_RS13875 6b364fffa1548b46b9972d1600c0d7d7 326 ProSitePatterns PS01053 Arginase family signature. 244 265 - T 28-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 CFK41_RS14080 eebbf718068b16cdd305087949a17b70 297 Pfam PF00701 Dihydrodipicolinate synthetase family 2 290 5.2E-31 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS14080 eebbf718068b16cdd305087949a17b70 297 SUPERFAMILY SSF51569 1 294 1.26E-61 T 28-03-2018 CFK41_RS14080 eebbf718068b16cdd305087949a17b70 297 Gene3D G3DSA:3.20.20.70 1 296 5.8E-69 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS14080 eebbf718068b16cdd305087949a17b70 297 PIRSF PIRSF001365 1 296 4.0E-55 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS14080 eebbf718068b16cdd305087949a17b70 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 69 87 2.3E-8 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS14080 eebbf718068b16cdd305087949a17b70 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 34 55 2.3E-8 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS14080 eebbf718068b16cdd305087949a17b70 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 126 143 2.3E-8 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS14080 eebbf718068b16cdd305087949a17b70 297 SMART SM01130 1 294 4.0E-53 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS10960 92b2f1bc143ebd6130f70510780fa535 195 SUPERFAMILY SSF53335 5 180 5.68E-28 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS10960 92b2f1bc143ebd6130f70510780fa535 195 Gene3D G3DSA:3.40.50.150 2 189 1.4E-31 T 28-03-2018 CFK41_RS10960 92b2f1bc143ebd6130f70510780fa535 195 Pfam PF13489 Methyltransferase domain 37 174 9.2E-14 T 28-03-2018 CFK41_RS17230 c4a60faca9906c498acf19c345c48588 299 SUPERFAMILY SSF48179 170 292 1.47E-30 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CFK41_RS17230 c4a60faca9906c498acf19c345c48588 299 Gene3D G3DSA:1.10.1040.10 180 298 7.3E-31 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CFK41_RS17230 c4a60faca9906c498acf19c345c48588 299 Gene3D G3DSA:3.40.50.720 1 179 1.5E-28 T 28-03-2018 CFK41_RS17230 c4a60faca9906c498acf19c345c48588 299 SUPERFAMILY SSF51735 10 162 2.54E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS17230 c4a60faca9906c498acf19c345c48588 299 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 11 162 1.5E-30 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CFK41_RS17230 c4a60faca9906c498acf19c345c48588 299 PIRSF PIRSF000103 4 298 7.2E-59 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CFK41_RS17230 c4a60faca9906c498acf19c345c48588 299 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 171 292 2.8E-31 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CFK41_RS08665 1818c978d08091231527f2f8b5ace629 335 SUPERFAMILY SSF54534 127 329 2.99E-28 T 28-03-2018 CFK41_RS08665 1818c978d08091231527f2f8b5ace629 335 Gene3D G3DSA:3.10.50.40 211 335 2.2E-29 T 28-03-2018 CFK41_RS08665 1818c978d08091231527f2f8b5ace629 335 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 240 328 1.1E-19 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain CFK41_RS08665 1818c978d08091231527f2f8b5ace629 335 Gene3D G3DSA:3.10.50.40 88 202 0.27 T 28-03-2018 CFK41_RS13480 fea22c41d0806f76ad54146503a39ea5 391 SUPERFAMILY SSF111331 68 379 3.27E-57 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CFK41_RS13480 fea22c41d0806f76ad54146503a39ea5 391 Gene3D G3DSA:3.40.50.10330 64 206 1.6E-23 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CFK41_RS13480 fea22c41d0806f76ad54146503a39ea5 391 SMART SM00046 71 196 0.0065 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CFK41_RS13480 fea22c41d0806f76ad54146503a39ea5 391 Pfam PF00781 Diacylglycerol kinase catalytic domain 72 192 2.3E-20 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CFK41_RS12755 73796760fe90ddc3bbd083ede543bb27 341 SUPERFAMILY SSF56112 49 327 1.9E-14 T 28-03-2018 IPR011009 Protein kinase-like domain CFK41_RS12755 73796760fe90ddc3bbd083ede543bb27 341 Gene3D G3DSA:1.10.510.10 194 331 2.4E-8 T 28-03-2018 CFK41_RS12755 73796760fe90ddc3bbd083ede543bb27 341 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 58 319 6.7E-20 T 28-03-2018 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 CFK41_RS03850 1b402111c85fb80fb6af220002639bd0 148 SUPERFAMILY SSF54909 17 126 1.07E-22 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CFK41_RS03850 1b402111c85fb80fb6af220002639bd0 148 Gene3D G3DSA:3.30.70.1060 1 130 3.2E-42 T 28-03-2018 CFK41_RS03850 1b402111c85fb80fb6af220002639bd0 148 Pfam PF03795 YCII-related domain 18 104 2.0E-11 T 28-03-2018 IPR005545 YCII-related CFK41_RS02755 93a3211313692c380511d3aae65afbf1 962 Gene3D G3DSA:2.60.40.1260 81 203 1.0E-16 T 28-03-2018 IPR001322 Lamin Tail Domain CFK41_RS02755 93a3211313692c380511d3aae65afbf1 962 Gene3D G3DSA:3.60.10.10 556 895 3.1E-23 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS02755 93a3211313692c380511d3aae65afbf1 962 Pfam PF00932 Lamin Tail Domain 90 198 2.7E-15 T 28-03-2018 IPR001322 Lamin Tail Domain CFK41_RS02755 93a3211313692c380511d3aae65afbf1 962 SUPERFAMILY SSF56219 600 841 3.45E-23 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS02755 93a3211313692c380511d3aae65afbf1 962 SUPERFAMILY SSF56219 553 563 3.45E-23 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS02755 93a3211313692c380511d3aae65afbf1 962 SUPERFAMILY SSF56219 870 895 3.45E-23 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS02755 93a3211313692c380511d3aae65afbf1 962 SUPERFAMILY SSF74853 89 200 7.72E-10 T 28-03-2018 IPR001322 Lamin Tail Domain CFK41_RS02755 93a3211313692c380511d3aae65afbf1 962 Gene3D G3DSA:2.40.50.200 273 389 6.1E-9 T 28-03-2018 CFK41_RS15855 a385017d0177271cf5624622daa2d00a 447 Gene3D G3DSA:3.30.1890.10 49 183 2.6E-5 T 28-03-2018 CFK41_RS00330 737f7ee16997156fc680f8a441b561f9 191 Gene3D G3DSA:3.40.430.10 4 189 6.2E-26 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CFK41_RS00330 737f7ee16997156fc680f8a441b561f9 191 Pfam PF01872 RibD C-terminal domain 5 183 4.9E-20 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CFK41_RS00330 737f7ee16997156fc680f8a441b561f9 191 SUPERFAMILY SSF53597 8 190 2.62E-20 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CFK41_RS04220 da815272c0320acce5dbd026c59ac73d 421 Pfam PF01699 Sodium/calcium exchanger protein 52 203 1.4E-12 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CFK41_RS04220 da815272c0320acce5dbd026c59ac73d 421 Pfam PF01699 Sodium/calcium exchanger protein 281 419 6.0E-6 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CFK41_RS01485 10ca50efd924c761fb59766f8c5ef59b 327 Gene3D G3DSA:2.115.10.20 2 312 1.3E-35 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CFK41_RS01485 10ca50efd924c761fb59766f8c5ef59b 327 SUPERFAMILY SSF75005 3 296 1.08E-33 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CFK41_RS01485 10ca50efd924c761fb59766f8c5ef59b 327 Pfam PF04616 Glycosyl hydrolases family 43 4 286 1.4E-26 T 28-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 CFK41_RS16360 270c63667ba4acf4d9f56485421c333a 594 SUPERFAMILY SSF48239 66 239 7.85E-5 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CFK41_RS16360 270c63667ba4acf4d9f56485421c333a 594 Gene3D G3DSA:1.50.10.20 138 303 2.1E-6 T 28-03-2018 CFK41_RS07405 42a83bf5eecca27215264143128c42b3 311 Gene3D G3DSA:3.40.630.30 2 140 2.9E-9 T 28-03-2018 CFK41_RS07405 42a83bf5eecca27215264143128c42b3 311 Pfam PF00583 Acetyltransferase (GNAT) family 21 92 6.0E-6 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS07405 42a83bf5eecca27215264143128c42b3 311 Gene3D G3DSA:3.40.630.30 141 297 0.11 T 28-03-2018 CFK41_RS07405 42a83bf5eecca27215264143128c42b3 311 SUPERFAMILY SSF55729 25 92 2.48E-9 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS02410 682e3ad6d6066526eb22ca713349f871 349 Pfam PF09084 NMT1/THI5 like 80 266 2.3E-11 T 28-03-2018 IPR015168 SsuA/THI5-like CFK41_RS02410 682e3ad6d6066526eb22ca713349f871 349 SUPERFAMILY SSF53850 74 268 1.03E-31 T 28-03-2018 CFK41_RS02410 682e3ad6d6066526eb22ca713349f871 349 Gene3D G3DSA:3.40.190.10 144 334 2.0E-26 T 28-03-2018 CFK41_RS02410 682e3ad6d6066526eb22ca713349f871 349 Gene3D G3DSA:3.40.190.10 44 143 6.6E-7 T 28-03-2018 CFK41_RS03680 7f8bed3d9a0271b6f6924d21b1239e3a 469 Gene3D G3DSA:3.90.550.10 27 344 1.1E-52 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS03680 7f8bed3d9a0271b6f6924d21b1239e3a 469 Pfam PF13641 Glycosyltransferase like family 2 56 325 7.3E-30 T 28-03-2018 CFK41_RS03680 7f8bed3d9a0271b6f6924d21b1239e3a 469 SUPERFAMILY SSF53448 56 104 6.59E-53 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS03680 7f8bed3d9a0271b6f6924d21b1239e3a 469 SUPERFAMILY SSF53448 132 367 6.59E-53 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS03630 7f838dc2763804e996028399a0d4c7e1 253 Pfam PF02517 CAAX protease self-immunity 149 238 1.6E-14 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CFK41_RS11305 3d323397d873bb1dd16b112bb851db64 256 Pfam PF03641 Possible lysine decarboxylase 109 237 3.5E-34 T 28-03-2018 IPR031100 LOG family CFK41_RS11305 3d323397d873bb1dd16b112bb851db64 256 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 67 240 2.6E-43 T 28-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG CFK41_RS11305 3d323397d873bb1dd16b112bb851db64 256 Gene3D G3DSA:3.40.50.450 43 252 6.4E-67 T 28-03-2018 CFK41_RS11305 3d323397d873bb1dd16b112bb851db64 256 SUPERFAMILY SSF102405 37 240 6.11E-62 T 28-03-2018 CFK41_RS05855 66319504c2c8f1d94a27355d88985462 322 Gene3D G3DSA:1.10.8.300 205 312 3.9E-30 T 28-03-2018 CFK41_RS05855 66319504c2c8f1d94a27355d88985462 322 SUPERFAMILY SSF52540 11 286 1.51E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS05855 66319504c2c8f1d94a27355d88985462 322 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 43 173 3.5E-63 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CFK41_RS05855 66319504c2c8f1d94a27355d88985462 322 PIRSF PIRSF002849 1 317 1.1E-130 T 28-03-2018 CFK41_RS05855 66319504c2c8f1d94a27355d88985462 322 Gene3D G3DSA:3.40.50.300 24 190 6.2E-27 T 28-03-2018 CFK41_RS08445 616e519d2c848ff5dd1a742f8f4db505 279 Pfam PF00480 ROK family 6 163 6.0E-20 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CFK41_RS08445 616e519d2c848ff5dd1a742f8f4db505 279 Gene3D G3DSA:3.30.420.40 124 253 3.5E-28 T 28-03-2018 CFK41_RS08445 616e519d2c848ff5dd1a742f8f4db505 279 Gene3D G3DSA:3.30.420.40 2 123 9.5E-24 T 28-03-2018 CFK41_RS08445 616e519d2c848ff5dd1a742f8f4db505 279 SUPERFAMILY SSF53067 4 248 1.73E-38 T 28-03-2018 CFK41_RS17015 b007d46524957b40fbcd125557cb1b25 286 Gene3D G3DSA:3.90.850.10 25 285 4.8E-73 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CFK41_RS17015 b007d46524957b40fbcd125557cb1b25 286 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 77 281 4.3E-62 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CFK41_RS17015 b007d46524957b40fbcd125557cb1b25 286 SUPERFAMILY SSF56529 66 284 3.79E-68 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CFK41_RS09315 a713d1be0300b2f7420e39590f5186d8 180 PRINTS PR01100 Shikimate kinase family signature 6 21 1.9E-15 T 28-03-2018 CFK41_RS09315 a713d1be0300b2f7420e39590f5186d8 180 PRINTS PR01100 Shikimate kinase family signature 76 85 1.9E-15 T 28-03-2018 CFK41_RS09315 a713d1be0300b2f7420e39590f5186d8 180 PRINTS PR01100 Shikimate kinase family signature 96 113 1.9E-15 T 28-03-2018 CFK41_RS09315 a713d1be0300b2f7420e39590f5186d8 180 PRINTS PR01100 Shikimate kinase family signature 30 43 1.9E-15 T 28-03-2018 CFK41_RS09315 a713d1be0300b2f7420e39590f5186d8 180 PRINTS PR01100 Shikimate kinase family signature 58 66 1.9E-15 T 28-03-2018 CFK41_RS09315 a713d1be0300b2f7420e39590f5186d8 180 Pfam PF01202 Shikimate kinase 12 167 1.0E-42 T 28-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CFK41_RS09315 a713d1be0300b2f7420e39590f5186d8 180 SUPERFAMILY SSF52540 4 167 9.77E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS09315 a713d1be0300b2f7420e39590f5186d8 180 Gene3D G3DSA:3.40.50.300 3 179 1.1E-31 T 28-03-2018 CFK41_RS09315 a713d1be0300b2f7420e39590f5186d8 180 Hamap MF_00109 Shikimate kinase [aroK]. 3 168 25.346 T 28-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CFK41_RS14730 0eb16bf27b2f9ea127fca7607e2132b0 241 Gene3D G3DSA:3.40.50.720 2 229 1.2E-21 T 28-03-2018 CFK41_RS14730 0eb16bf27b2f9ea127fca7607e2132b0 241 SUPERFAMILY SSF51735 3 230 8.0E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS14730 0eb16bf27b2f9ea127fca7607e2132b0 241 Pfam PF00106 short chain dehydrogenase 3 191 9.4E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS02965 2ba51797a733f640c9a8c5740b031afa 79 Hamap MF_00631 Cell division protein CrgA [crgA]. 6 79 17.622 T 28-03-2018 IPR009619 Cell division protein CrgA CFK41_RS02965 2ba51797a733f640c9a8c5740b031afa 79 Pfam PF06781 Cell division protein CrgA 5 79 3.0E-20 T 28-03-2018 IPR009619 Cell division protein CrgA CFK41_RS17220 55caa69047726bc6b002d3da86531591 276 Gene3D G3DSA:3.20.20.150 2 273 1.4E-48 T 28-03-2018 CFK41_RS17220 55caa69047726bc6b002d3da86531591 276 Pfam PF01261 Xylose isomerase-like TIM barrel 27 219 2.8E-21 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS17220 55caa69047726bc6b002d3da86531591 276 SUPERFAMILY SSF51658 8 272 1.24E-42 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS05530 71622645428ee66f466bcaf9700a20fe 348 Pfam PF05661 Protein of unknown function (DUF808) 4 298 1.3E-121 T 28-03-2018 IPR008526 Inner membrane protein YedI CFK41_RS05530 71622645428ee66f466bcaf9700a20fe 348 PIRSF PIRSF016660 1 308 2.8E-112 T 28-03-2018 IPR008526 Inner membrane protein YedI CFK41_RS07875 b48337c95d36d4fc2deca9189496a170 635 Pfam PF13454 FAD-NAD(P)-binding 9 187 1.7E-28 T 28-03-2018 CFK41_RS07875 b48337c95d36d4fc2deca9189496a170 635 Gene3D G3DSA:3.50.50.60 1 225 2.9E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS07875 b48337c95d36d4fc2deca9189496a170 635 SUPERFAMILY SSF51905 1 193 1.3E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS07875 b48337c95d36d4fc2deca9189496a170 635 Gene3D G3DSA:3.50.50.60 331 634 0.13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS09075 3c631333734ee0b570d4f4e89d83ba0a 221 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 12 200 2.0E-13 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CFK41_RS09075 3c631333734ee0b570d4f4e89d83ba0a 221 SUPERFAMILY SSF52266 5 212 2.44E-20 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CFK41_RS09075 3c631333734ee0b570d4f4e89d83ba0a 221 Gene3D G3DSA:3.40.50.1110 3 215 3.7E-21 T 28-03-2018 CFK41_RS12030 fa1c4fde680d042f9632a546cc43ccaf 303 Gene3D G3DSA:3.30.70.1350 216 296 2.8E-15 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CFK41_RS12030 fa1c4fde680d042f9632a546cc43ccaf 303 SUPERFAMILY SSF160240 218 293 5.1E-10 T 28-03-2018 CFK41_RS12030 fa1c4fde680d042f9632a546cc43ccaf 303 Pfam PF01545 Cation efflux family 23 213 1.8E-36 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CFK41_RS12030 fa1c4fde680d042f9632a546cc43ccaf 303 Gene3D G3DSA:1.20.1510.10 17 213 1.1E-43 T 28-03-2018 CFK41_RS12030 fa1c4fde680d042f9632a546cc43ccaf 303 SUPERFAMILY SSF161111 18 213 7.19E-44 T 28-03-2018 CFK41_RS12030 fa1c4fde680d042f9632a546cc43ccaf 303 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 19 294 2.1E-69 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CFK41_RS00795 03d44063b6a25f36f90e576373e715b8 254 SUPERFAMILY SSF52540 2 229 8.11E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS00795 03d44063b6a25f36f90e576373e715b8 254 Gene3D G3DSA:3.40.50.300 1 234 7.2E-56 T 28-03-2018 CFK41_RS00795 03d44063b6a25f36f90e576373e715b8 254 Pfam PF00005 ABC transporter 22 167 1.1E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS00795 03d44063b6a25f36f90e576373e715b8 254 SMART SM00382 29 216 3.1E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS05985 7c9e449180686baa3e564c2b0541fcd8 289 SUPERFAMILY SSF53474 213 286 2.16E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS05985 7c9e449180686baa3e564c2b0541fcd8 289 SUPERFAMILY SSF53474 19 130 2.16E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS05985 7c9e449180686baa3e564c2b0541fcd8 289 Gene3D G3DSA:3.40.50.1820 16 286 4.2E-19 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS09895 013272899718e6964d5775a8f7ee8428 470 Gene3D G3DSA:3.40.630.10 22 218 9.7E-37 T 28-03-2018 CFK41_RS09895 013272899718e6964d5775a8f7ee8428 470 SUPERFAMILY SSF53187 24 215 4.29E-50 T 28-03-2018 CFK41_RS09895 013272899718e6964d5775a8f7ee8428 470 SUPERFAMILY SSF53187 376 459 4.29E-50 T 28-03-2018 CFK41_RS09895 013272899718e6964d5775a8f7ee8428 470 Pfam PF07687 Peptidase dimerisation domain 213 362 6.3E-19 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CFK41_RS09895 013272899718e6964d5775a8f7ee8428 470 Gene3D G3DSA:3.30.70.360 219 373 2.7E-37 T 28-03-2018 CFK41_RS09895 013272899718e6964d5775a8f7ee8428 470 Pfam PF01546 Peptidase family M20/M25/M40 101 451 1.1E-28 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CFK41_RS06975 12824ce5cebf7d3cc5d71af0c3191f30 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 281 1.0E-11 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS06975 12824ce5cebf7d3cc5d71af0c3191f30 297 SUPERFAMILY SSF161098 25 297 3.4E-63 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS06975 12824ce5cebf7d3cc5d71af0c3191f30 297 Gene3D G3DSA:1.10.3720.10 19 284 1.4E-34 T 28-03-2018 CFK41_RS08770 9a0826980cf75c43a7376607d1efe976 116 Pfam PF13397 RNA polymerase-binding protein 4 106 4.1E-41 T 28-03-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 CFK41_RS08770 9a0826980cf75c43a7376607d1efe976 116 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 16 115 25.14 T 28-03-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 CFK41_RS05385 8e44b5c0e445fd6ca583d136eb5318dc 106 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 75 1.8E-12 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CFK41_RS05385 8e44b5c0e445fd6ca583d136eb5318dc 106 SUPERFAMILY SSF54909 1 94 2.46E-22 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CFK41_RS05385 8e44b5c0e445fd6ca583d136eb5318dc 106 Gene3D G3DSA:3.30.70.100 1 93 1.1E-16 T 28-03-2018 CFK41_RS07800 4aca6439c9e6fc95469eb3cb012f496e 291 Gene3D G3DSA:1.10.3720.10 18 279 4.1E-43 T 28-03-2018 CFK41_RS07800 4aca6439c9e6fc95469eb3cb012f496e 291 SUPERFAMILY SSF161098 23 291 4.32E-66 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS07800 4aca6439c9e6fc95469eb3cb012f496e 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 283 2.8E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS15665 b338e2160b2fd241f0b970df6847e4f2 405 SUPERFAMILY SSF103473 9 394 8.63E-30 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS15665 b338e2160b2fd241f0b970df6847e4f2 405 Gene3D G3DSA:1.20.1250.20 211 394 4.6E-14 T 28-03-2018 CFK41_RS15665 b338e2160b2fd241f0b970df6847e4f2 405 Gene3D G3DSA:1.20.1250.20 11 200 1.1E-8 T 28-03-2018 CFK41_RS07815 1bd56353fdac2e1c37e0638657c432fc 330 SMART SM00354 9 79 1.1E-25 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS07815 1bd56353fdac2e1c37e0638657c432fc 330 SUPERFAMILY SSF47413 9 67 4.06E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS07815 1bd56353fdac2e1c37e0638657c432fc 330 Pfam PF00356 Bacterial regulatory proteins, lacI family 13 56 3.4E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS07815 1bd56353fdac2e1c37e0638657c432fc 330 Gene3D G3DSA:3.40.50.2300 174 330 1.7E-4 T 28-03-2018 CFK41_RS07815 1bd56353fdac2e1c37e0638657c432fc 330 SUPERFAMILY SSF53822 66 319 1.75E-12 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS07815 1bd56353fdac2e1c37e0638657c432fc 330 Gene3D G3DSA:3.40.50.2300 62 173 1.3E-18 T 28-03-2018 CFK41_RS07815 1bd56353fdac2e1c37e0638657c432fc 330 Gene3D G3DSA:1.10.260.40 11 61 1.6E-22 T 28-03-2018 CFK41_RS13540 f783c208f604583369556aef716d3fab 347 Gene3D G3DSA:3.40.710.10 30 327 4.0E-96 T 28-03-2018 CFK41_RS13540 f783c208f604583369556aef716d3fab 347 Pfam PF04960 Glutaminase 53 324 1.4E-91 T 28-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CFK41_RS13540 f783c208f604583369556aef716d3fab 347 SUPERFAMILY SSF56601 43 326 1.54E-82 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CFK41_RS13540 f783c208f604583369556aef716d3fab 347 TIGRFAM TIGR03814 Gln_ase: glutaminase A 53 323 1.6E-79 T 28-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CFK41_RS11810 7f34d656e4af60327381341171662a7d 182 TIGRFAM TIGR03543 divI1A_rptt_fam: DivIVA domain repeat protein 5 181 8.2E-59 T 28-03-2018 IPR019932 Conserved hypothetical protein CHP03543 CFK41_RS11810 7f34d656e4af60327381341171662a7d 182 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 40 70 9.3E-6 T 28-03-2018 IPR019933 DivIVA domain CFK41_RS17205 bf5ee734b8aa0155a41aaf76e999e581 292 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 21 280 6.5E-39 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CFK41_RS17205 bf5ee734b8aa0155a41aaf76e999e581 292 SUPERFAMILY SSF52518 11 279 3.46E-68 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CFK41_RS17205 bf5ee734b8aa0155a41aaf76e999e581 292 Gene3D G3DSA:3.40.50.970 10 289 1.3E-56 T 28-03-2018 CFK41_RS02620 6ad99b6dab0ea59a468a8c10f9e48b1f 199 SUPERFAMILY SSF46689 4 63 5.49E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS02620 6ad99b6dab0ea59a468a8c10f9e48b1f 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 52 5.2E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS02620 6ad99b6dab0ea59a468a8c10f9e48b1f 199 Gene3D G3DSA:1.10.357.10 2 193 6.6E-24 T 28-03-2018 CFK41_RS02620 6ad99b6dab0ea59a468a8c10f9e48b1f 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 3.2E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS02620 6ad99b6dab0ea59a468a8c10f9e48b1f 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 3.2E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS01430 b779a84f1b24e808b0ed74abc038b514 332 Gene3D G3DSA:1.10.260.40 23 60 5.4E-19 T 28-03-2018 CFK41_RS01430 b779a84f1b24e808b0ed74abc038b514 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 53 1.5E-14 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS01430 b779a84f1b24e808b0ed74abc038b514 332 Gene3D G3DSA:1.10.10.60 4 22 1.6E-4 T 28-03-2018 CFK41_RS01430 b779a84f1b24e808b0ed74abc038b514 332 Gene3D G3DSA:3.40.50.2300 178 328 1.7E-31 T 28-03-2018 CFK41_RS01430 b779a84f1b24e808b0ed74abc038b514 332 SMART SM00354 6 76 1.3E-18 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS01430 b779a84f1b24e808b0ed74abc038b514 332 SUPERFAMILY SSF47413 5 64 1.42E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS01430 b779a84f1b24e808b0ed74abc038b514 332 Pfam PF13377 Periplasmic binding protein-like domain 172 326 1.8E-31 T 28-03-2018 CFK41_RS01430 b779a84f1b24e808b0ed74abc038b514 332 Gene3D G3DSA:3.40.50.2300 61 177 1.4E-8 T 28-03-2018 CFK41_RS01430 b779a84f1b24e808b0ed74abc038b514 332 SUPERFAMILY SSF53822 68 330 3.93E-34 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS08035 58890b99564686eb2ca9b29c76b494fd 332 Gene3D G3DSA:3.20.20.150 32 315 3.4E-50 T 28-03-2018 CFK41_RS08035 58890b99564686eb2ca9b29c76b494fd 332 SUPERFAMILY SSF51658 53 303 2.76E-42 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS08035 58890b99564686eb2ca9b29c76b494fd 332 Pfam PF01261 Xylose isomerase-like TIM barrel 72 259 2.2E-22 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS15580 4a28d91a0f6fdb18fb727eda77c0cc3f 207 SMART SM00448 8 121 6.1E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS15580 4a28d91a0f6fdb18fb727eda77c0cc3f 207 SUPERFAMILY SSF52172 7 136 1.27E-29 T 28-03-2018 IPR011006 CheY-like superfamily CFK41_RS15580 4a28d91a0f6fdb18fb727eda77c0cc3f 207 SUPERFAMILY SSF46894 134 207 1.84E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CFK41_RS15580 4a28d91a0f6fdb18fb727eda77c0cc3f 207 Gene3D G3DSA:3.40.50.2300 7 131 1.2E-32 T 28-03-2018 CFK41_RS15580 4a28d91a0f6fdb18fb727eda77c0cc3f 207 Pfam PF00072 Response regulator receiver domain 10 121 2.2E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS15580 4a28d91a0f6fdb18fb727eda77c0cc3f 207 SMART SM00421 144 201 1.4E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS15580 4a28d91a0f6fdb18fb727eda77c0cc3f 207 Gene3D G3DSA:1.10.10.10 132 207 9.5E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS15580 4a28d91a0f6fdb18fb727eda77c0cc3f 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 189 1.6E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS15580 4a28d91a0f6fdb18fb727eda77c0cc3f 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 177 1.6E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS15580 4a28d91a0f6fdb18fb727eda77c0cc3f 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 147 161 1.6E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS15580 4a28d91a0f6fdb18fb727eda77c0cc3f 207 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 201 3.1E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CFK41_RS02275 87eeb8a512ed930a704121cd842a9bc7 433 Pfam PF00962 Adenosine/AMP deaminase 65 401 6.7E-53 T 28-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 CFK41_RS02275 87eeb8a512ed930a704121cd842a9bc7 433 SUPERFAMILY SSF51556 301 402 5.9E-67 T 28-03-2018 IPR032466 Metal-dependent hydrolase CFK41_RS02275 87eeb8a512ed930a704121cd842a9bc7 433 SUPERFAMILY SSF51556 73 257 5.9E-67 T 28-03-2018 IPR032466 Metal-dependent hydrolase CFK41_RS02275 87eeb8a512ed930a704121cd842a9bc7 433 SUPERFAMILY SSF51556 7 35 5.9E-67 T 28-03-2018 IPR032466 Metal-dependent hydrolase CFK41_RS02275 87eeb8a512ed930a704121cd842a9bc7 433 Gene3D G3DSA:3.20.20.140 6 403 2.1E-76 T 28-03-2018 CFK41_RS10375 16b1ab92faa410af82e0c00a28d6c5a2 210 Gene3D G3DSA:3.90.1210.10 45 110 2.9E-14 T 28-03-2018 CFK41_RS10375 16b1ab92faa410af82e0c00a28d6c5a2 210 SMART SM00858 47 109 2.7E-10 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CFK41_RS10375 16b1ab92faa410af82e0c00a28d6c5a2 210 SUPERFAMILY SSF51269 50 109 3.14E-6 T 28-03-2018 IPR006190 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal Reactome: R-HSA-4085001 CFK41_RS10375 16b1ab92faa410af82e0c00a28d6c5a2 210 Pfam PF08666 SAF domain 48 108 1.5E-11 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CFK41_RS16065 007781234340eb4707f0722032700515 552 SUPERFAMILY SSF52091 436 542 9.03E-16 T 28-03-2018 IPR002645 STAS domain CFK41_RS16065 007781234340eb4707f0722032700515 552 Pfam PF01740 STAS domain 439 530 5.2E-12 T 28-03-2018 IPR002645 STAS domain CFK41_RS16065 007781234340eb4707f0722032700515 552 Gene3D G3DSA:3.30.750.24 425 551 1.5E-22 T 28-03-2018 IPR002645 STAS domain CFK41_RS16065 007781234340eb4707f0722032700515 552 Pfam PF00916 Sulfate permease family 26 389 1.6E-64 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CFK41_RS05655 a4e492d87b79e50f7dc2b78aed070cb4 239 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 27 230 1.1E-58 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CFK41_RS05655 a4e492d87b79e50f7dc2b78aed070cb4 239 Gene3D G3DSA:3.40.50.880 21 239 2.0E-46 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS05655 a4e492d87b79e50f7dc2b78aed070cb4 239 PIRSF PIRSF000495 25 234 4.7E-59 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CFK41_RS05655 a4e492d87b79e50f7dc2b78aed070cb4 239 SUPERFAMILY SSF52317 26 230 9.32E-50 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS05655 a4e492d87b79e50f7dc2b78aed070cb4 239 Pfam PF00117 Glutamine amidotransferase class-I 29 221 5.1E-18 T 28-03-2018 IPR017926 Glutamine amidotransferase CFK41_RS05655 a4e492d87b79e50f7dc2b78aed070cb4 239 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 26 231 30.832 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CFK41_RS07110 bd9c18f1384bcd95793115e69f13b4c2 675 Gene3D G3DSA:2.60.40.10 13 113 1.2E-34 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS07110 bd9c18f1384bcd95793115e69f13b4c2 675 SUPERFAMILY SSF51445 212 572 6.82E-79 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS07110 bd9c18f1384bcd95793115e69f13b4c2 675 SMART SM00642 211 546 7.7E-6 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CFK41_RS07110 bd9c18f1384bcd95793115e69f13b4c2 675 Gene3D G3DSA:2.60.40.1180 576 675 3.7E-21 T 28-03-2018 CFK41_RS07110 bd9c18f1384bcd95793115e69f13b4c2 675 Gene3D G3DSA:1.20.58.280 114 186 1.9E-16 T 28-03-2018 CFK41_RS07110 bd9c18f1384bcd95793115e69f13b4c2 675 Pfam PF11896 Domain of unknown function (DUF3416) 15 205 8.4E-48 T 28-03-2018 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16 CFK41_RS07110 bd9c18f1384bcd95793115e69f13b4c2 675 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 13 671 41.479 T 28-03-2018 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16 CFK41_RS07110 bd9c18f1384bcd95793115e69f13b4c2 675 Gene3D G3DSA:3.20.20.80 208 575 2.4E-61 T 28-03-2018 CFK41_RS07110 bd9c18f1384bcd95793115e69f13b4c2 675 Pfam PF00128 Alpha amylase, catalytic domain 240 340 1.7E-6 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CFK41_RS08075 a11f9e63d75289c033821db5b5f44928 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 2 84 3.1E-25 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS08075 a11f9e63d75289c033821db5b5f44928 88 Pfam PF01649 Ribosomal protein S20 2 83 5.6E-27 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS08075 a11f9e63d75289c033821db5b5f44928 88 Gene3D G3DSA:1.20.58.110 1 88 1.9E-28 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS08075 a11f9e63d75289c033821db5b5f44928 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 16.435 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS08075 a11f9e63d75289c033821db5b5f44928 88 SUPERFAMILY SSF46992 3 86 5.89E-28 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS08075 a11f9e63d75289c033821db5b5f44928 88 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 81 3.0E-19 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS16185 27e75335ba6e4754d8354adfeadf7d5d 201 Pfam PF13302 Acetyltransferase (GNAT) domain 31 180 3.3E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS16185 27e75335ba6e4754d8354adfeadf7d5d 201 SUPERFAMILY SSF55729 25 181 5.91E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS16185 27e75335ba6e4754d8354adfeadf7d5d 201 Gene3D G3DSA:3.40.630.30 10 197 9.8E-17 T 28-03-2018 CFK41_RS03655 d7bce035854ef529ae83d083949e505f 363 SUPERFAMILY SSF53383 31 355 7.93E-68 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS03655 d7bce035854ef529ae83d083949e505f 363 Gene3D G3DSA:3.90.1150.10 254 361 2.5E-17 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS03655 d7bce035854ef529ae83d083949e505f 363 Gene3D G3DSA:3.40.640.10 47 253 2.7E-34 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS03655 d7bce035854ef529ae83d083949e505f 363 Pfam PF00155 Aminotransferase class I and II 36 323 1.0E-38 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CFK41_RS15375 a3190ded89afa3e2e8674c1112741585 435 Pfam PF07690 Major Facilitator Superfamily 283 427 3.2E-8 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS15375 a3190ded89afa3e2e8674c1112741585 435 Pfam PF00083 Sugar (and other) transporter 23 231 1.6E-19 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CFK41_RS15375 a3190ded89afa3e2e8674c1112741585 435 ProSitePatterns PS00217 Sugar transport proteins signature 2. 128 153 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CFK41_RS15375 a3190ded89afa3e2e8674c1112741585 435 Gene3D G3DSA:1.20.1250.20 229 431 2.6E-19 T 28-03-2018 CFK41_RS15375 a3190ded89afa3e2e8674c1112741585 435 SUPERFAMILY SSF103473 14 429 2.75E-53 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS15375 a3190ded89afa3e2e8674c1112741585 435 Gene3D G3DSA:1.20.1250.20 14 228 9.9E-22 T 28-03-2018 CFK41_RS03940 dde88c589f3960f552c7c04a135cf899 509 Gene3D G3DSA:3.30.360.10 147 369 1.8E-8 T 28-03-2018 CFK41_RS03940 dde88c589f3960f552c7c04a135cf899 509 Gene3D G3DSA:3.40.50.720 1 146 8.3E-24 T 28-03-2018 CFK41_RS03940 dde88c589f3960f552c7c04a135cf899 509 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 131 1.5E-12 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS03940 dde88c589f3960f552c7c04a135cf899 509 SUPERFAMILY SSF51735 3 146 3.6E-20 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS17000 026c63adf9a5db580aaaf912746a901d 332 Pfam PF00248 Aldo/keto reductase family 11 314 1.1E-54 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS17000 026c63adf9a5db580aaaf912746a901d 332 Gene3D G3DSA:3.20.20.100 2 329 9.9E-66 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS17000 026c63adf9a5db580aaaf912746a901d 332 SUPERFAMILY SSF51430 6 317 6.15E-66 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS09350 d467f2abd1a67b04e1286f925b0490ad 163 SUPERFAMILY SSF54637 40 161 1.13E-21 T 28-03-2018 IPR029069 HotDog domain CFK41_RS09350 d467f2abd1a67b04e1286f925b0490ad 163 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 41 156 5.0E-24 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CFK41_RS09350 d467f2abd1a67b04e1286f925b0490ad 163 Pfam PF03061 Thioesterase superfamily 71 149 1.4E-11 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CFK41_RS09350 d467f2abd1a67b04e1286f925b0490ad 163 Gene3D G3DSA:3.10.129.10 26 163 5.2E-21 T 28-03-2018 CFK41_RS02770 66f0170e151ccb9834643bf0af43dc67 221 Gene3D G3DSA:3.30.530.20 6 197 2.9E-26 T 28-03-2018 IPR023393 START-like domain CFK41_RS02770 66f0170e151ccb9834643bf0af43dc67 221 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 36 134 5.4E-10 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CFK41_RS02770 66f0170e151ccb9834643bf0af43dc67 221 SUPERFAMILY SSF55961 20 158 1.26E-23 T 28-03-2018 CFK41_RS13280 c1f77a0bda8990bd8c07186bafc37583 191 Pfam PF13673 Acetyltransferase (GNAT) domain 56 169 9.0E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS13280 c1f77a0bda8990bd8c07186bafc37583 191 SUPERFAMILY SSF55729 7 164 2.79E-30 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS13280 c1f77a0bda8990bd8c07186bafc37583 191 Gene3D G3DSA:3.40.630.30 13 108 2.6E-18 T 28-03-2018 CFK41_RS13280 c1f77a0bda8990bd8c07186bafc37583 191 Gene3D G3DSA:3.40.630.30 109 191 4.6E-15 T 28-03-2018 CFK41_RS02100 f7f3d5426ca73898975325ad7e99dc93 334 Gene3D G3DSA:3.20.20.100 1 333 1.3E-93 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS02100 f7f3d5426ca73898975325ad7e99dc93 334 SUPERFAMILY SSF51430 1 316 1.44E-96 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS02100 f7f3d5426ca73898975325ad7e99dc93 334 PRINTS PR00069 Aldo-keto reductase signature 106 124 7.6E-6 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS02100 f7f3d5426ca73898975325ad7e99dc93 334 PRINTS PR00069 Aldo-keto reductase signature 40 64 7.6E-6 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS02100 f7f3d5426ca73898975325ad7e99dc93 334 PRINTS PR00069 Aldo-keto reductase signature 248 272 7.6E-6 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS02100 f7f3d5426ca73898975325ad7e99dc93 334 Pfam PF00248 Aldo/keto reductase family 15 314 5.8E-75 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS13185 f6c178879f804bc0d10a44c0d2eac7ce 129 Pfam PF06993 Protein of unknown function (DUF1304) 12 123 1.9E-26 T 28-03-2018 IPR009732 Protein of unknown function DUF1304 CFK41_RS12720 cfab9b94b0cf9ba965cfebcc3b78ab0d 338 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 40 170 6.8E-63 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CFK41_RS12720 cfab9b94b0cf9ba965cfebcc3b78ab0d 338 PIRSF PIRSF002849 1 315 3.0E-129 T 28-03-2018 CFK41_RS12720 cfab9b94b0cf9ba965cfebcc3b78ab0d 338 Gene3D G3DSA:1.10.8.300 202 310 3.5E-30 T 28-03-2018 CFK41_RS12720 cfab9b94b0cf9ba965cfebcc3b78ab0d 338 Gene3D G3DSA:3.40.50.300 21 187 7.2E-26 T 28-03-2018 CFK41_RS12720 cfab9b94b0cf9ba965cfebcc3b78ab0d 338 SUPERFAMILY SSF52540 19 286 2.33E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS06980 897b5ff5cc00cd6a4381df5954f22a05 326 Gene3D G3DSA:1.10.3720.10 79 310 1.7E-44 T 28-03-2018 CFK41_RS06980 897b5ff5cc00cd6a4381df5954f22a05 326 Gene3D G3DSA:1.20.58.370 19 63 1.4E-5 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CFK41_RS06980 897b5ff5cc00cd6a4381df5954f22a05 326 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 301 8.4E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS06980 897b5ff5cc00cd6a4381df5954f22a05 326 SUPERFAMILY SSF161098 73 302 8.24E-60 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS00395 bb64c5baac13f8174ffe6a513a1ea7c4 450 Pfam PF09861 Domain of unknown function (DUF2088) 52 210 7.3E-22 T 28-03-2018 IPR018657 LarA-like, N-terminal CFK41_RS00160 a9f55748e20f4ddbbd27187344f3f4dd 432 Pfam PF01636 Phosphotransferase enzyme family 61 234 1.5E-12 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CFK41_RS00160 a9f55748e20f4ddbbd27187344f3f4dd 432 SUPERFAMILY SSF52540 280 417 1.41E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS00160 a9f55748e20f4ddbbd27187344f3f4dd 432 SUPERFAMILY SSF56112 44 250 4.23E-21 T 28-03-2018 IPR011009 Protein kinase-like domain CFK41_RS00160 a9f55748e20f4ddbbd27187344f3f4dd 432 Gene3D G3DSA:3.40.50.300 282 424 5.0E-17 T 28-03-2018 CFK41_RS00160 a9f55748e20f4ddbbd27187344f3f4dd 432 Pfam PF13671 AAA domain 284 418 8.7E-19 T 28-03-2018 CFK41_RS00160 a9f55748e20f4ddbbd27187344f3f4dd 432 Gene3D G3DSA:3.90.1200.10 99 261 4.1E-11 T 28-03-2018 CFK41_RS13075 b5ae57a3e08bbba82f975367c9a7da5c 279 SUPERFAMILY SSF102522 2 165 2.88E-55 T 28-03-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal CFK41_RS13075 b5ae57a3e08bbba82f975367c9a7da5c 279 SUPERFAMILY SSF101852 169 274 2.62E-23 T 28-03-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal CFK41_RS13075 b5ae57a3e08bbba82f975367c9a7da5c 279 PIRSF PIRSF006779 1 276 9.9E-90 T 28-03-2018 IPR002747 SAM-dependent chlorinase/fluorinase CFK41_RS13075 b5ae57a3e08bbba82f975367c9a7da5c 279 Gene3D G3DSA:3.40.50.10790 2 164 1.1E-53 T 28-03-2018 CFK41_RS13075 b5ae57a3e08bbba82f975367c9a7da5c 279 Gene3D G3DSA:2.40.30.90 165 279 1.9E-22 T 28-03-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal CFK41_RS13075 b5ae57a3e08bbba82f975367c9a7da5c 279 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 4 270 3.8E-71 T 28-03-2018 IPR002747 SAM-dependent chlorinase/fluorinase CFK41_RS12020 384d5d255c74201b091de22ae2780770 622 SMART SM00382 399 585 5.8E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS12020 384d5d255c74201b091de22ae2780770 622 Pfam PF00005 ABC transporter 390 539 8.5E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS12020 384d5d255c74201b091de22ae2780770 622 SUPERFAMILY SSF52540 368 607 1.03E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS12020 384d5d255c74201b091de22ae2780770 622 Gene3D G3DSA:3.40.50.300 363 614 3.6E-73 T 28-03-2018 CFK41_RS12020 384d5d255c74201b091de22ae2780770 622 ProSitePatterns PS00211 ABC transporters family signature. 511 525 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS12020 384d5d255c74201b091de22ae2780770 622 SUPERFAMILY SSF90123 33 359 2.35E-63 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS12020 384d5d255c74201b091de22ae2780770 622 Gene3D G3DSA:1.20.1560.10 19 358 1.7E-56 T 28-03-2018 CFK41_RS12020 384d5d255c74201b091de22ae2780770 622 Pfam PF00664 ABC transporter transmembrane region 48 322 1.7E-31 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS04500 6e130b64e4aa98ccd0a9fc83cbb72a28 297 SUPERFAMILY SSF56112 89 249 1.91E-12 T 28-03-2018 IPR011009 Protein kinase-like domain CFK41_RS04500 6e130b64e4aa98ccd0a9fc83cbb72a28 297 Gene3D G3DSA:1.10.510.10 85 277 4.9E-14 T 28-03-2018 CFK41_RS10975 d8eb00b4d7dea487c75b430ae3e382dc 240 SUPERFAMILY SSF48498 103 219 9.39E-21 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CFK41_RS10975 d8eb00b4d7dea487c75b430ae3e382dc 240 Gene3D G3DSA:1.10.10.60 1 74 2.5E-12 T 28-03-2018 CFK41_RS10975 d8eb00b4d7dea487c75b430ae3e382dc 240 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 73 7.9E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS10975 d8eb00b4d7dea487c75b430ae3e382dc 240 SUPERFAMILY SSF46689 18 92 1.65E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS10975 d8eb00b4d7dea487c75b430ae3e382dc 240 Gene3D G3DSA:1.10.357.10 75 239 1.8E-29 T 28-03-2018 CFK41_RS02400 55a681bff685a9fad8d7fb008af297cc 667 Pfam PF03616 Sodium/glutamate symporter 201 573 5.3E-15 T 28-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 CFK41_RS10920 f1ca6195af9eb79151327f512324cf5b 238 Pfam PF07729 FCD domain 76 207 1.5E-20 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS10920 f1ca6195af9eb79151327f512324cf5b 238 Gene3D G3DSA:1.10.10.10 1 63 4.0E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS10920 f1ca6195af9eb79151327f512324cf5b 238 Gene3D G3DSA:1.20.120.530 64 228 1.1E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS10920 f1ca6195af9eb79151327f512324cf5b 238 SUPERFAMILY SSF48008 74 215 1.15E-18 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS10920 f1ca6195af9eb79151327f512324cf5b 238 SUPERFAMILY SSF46785 4 94 2.42E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS10920 f1ca6195af9eb79151327f512324cf5b 238 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 65 1.4E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS10920 f1ca6195af9eb79151327f512324cf5b 238 SMART SM00345 7 65 1.4E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS10920 f1ca6195af9eb79151327f512324cf5b 238 SMART SM00895 75 208 1.0E-10 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS01070 0303966bdd77d3cd67c562a646609365 274 SUPERFAMILY SSF56235 2 263 4.79E-21 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CFK41_RS01070 0303966bdd77d3cd67c562a646609365 274 Pfam PF13230 Glutamine amidotransferases class-II 1 209 3.2E-14 T 28-03-2018 IPR026869 Putative glutamine amidotransferase type 2 CFK41_RS01070 0303966bdd77d3cd67c562a646609365 274 Gene3D G3DSA:3.60.20.10 1 267 3.4E-26 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CFK41_RS17500 8075962e3d92ba716f3c87e91dc64198 223 Gene3D G3DSA:3.30.300.20 75 153 3.9E-16 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CFK41_RS17500 8075962e3d92ba716f3c87e91dc64198 223 Gene3D G3DSA:3.30.1370.50 155 223 2.3E-17 T 28-03-2018 IPR001374 R3H domain GO:0003676 CFK41_RS17500 8075962e3d92ba716f3c87e91dc64198 223 SUPERFAMILY SSF82708 181 221 1.04E-10 T 28-03-2018 IPR001374 R3H domain GO:0003676 CFK41_RS17500 8075962e3d92ba716f3c87e91dc64198 223 Pfam PF01424 R3H domain 164 221 3.6E-13 T 28-03-2018 IPR001374 R3H domain GO:0003676 CFK41_RS17500 8075962e3d92ba716f3c87e91dc64198 223 SMART SM00393 144 222 7.3E-22 T 28-03-2018 IPR001374 R3H domain GO:0003676 CFK41_RS16040 095643f72760dabe04cdbfc8731f0d88 162 Pfam PF09860 Uncharacterized protein conserved in bacteria (DUF2087) 105 158 1.5E-10 T 28-03-2018 IPR018656 Domain of unknown function DUF2087 CFK41_RS11800 40a903dd6d7ce9615e1f39252d406c7c 447 SUPERFAMILY SSF50156 132 242 4.21E-14 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CFK41_RS11800 40a903dd6d7ce9615e1f39252d406c7c 447 Gene3D G3DSA:2.30.42.10 22 247 3.7E-14 T 28-03-2018 CFK41_RS11800 40a903dd6d7ce9615e1f39252d406c7c 447 Pfam PF13180 PDZ domain 186 243 9.9E-7 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CFK41_RS11800 40a903dd6d7ce9615e1f39252d406c7c 447 Pfam PF02163 Peptidase family M50 13 397 3.6E-42 T 28-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CFK41_RS04190 064e2795b9de7cc4da926987aaa38b1b 411 SUPERFAMILY SSF53067 77 372 2.27E-31 T 28-03-2018 CFK41_RS04190 064e2795b9de7cc4da926987aaa38b1b 411 Gene3D G3DSA:3.30.420.40 69 193 9.4E-17 T 28-03-2018 CFK41_RS04190 064e2795b9de7cc4da926987aaa38b1b 411 Gene3D G3DSA:1.10.10.10 1 68 2.0E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS04190 064e2795b9de7cc4da926987aaa38b1b 411 Pfam PF00480 ROK family 79 369 3.2E-24 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CFK41_RS04190 064e2795b9de7cc4da926987aaa38b1b 411 SUPERFAMILY SSF46785 2 58 3.67E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS04190 064e2795b9de7cc4da926987aaa38b1b 411 Gene3D G3DSA:3.30.420.40 194 380 3.4E-37 T 28-03-2018 CFK41_RS08720 db8377f07ce8b2c866998075b4de9a6e 371 Pfam PF12982 Protein of unknown function (DUF3866) 35 361 4.2E-119 T 28-03-2018 IPR024479 Protein of unknown function DUF3866 CFK41_RS13985 73169de6ad0f85c9f92c3e87a6ba178c 194 SUPERFAMILY SSF47413 9 76 7.04E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS13985 73169de6ad0f85c9f92c3e87a6ba178c 194 Gene3D G3DSA:1.10.260.40 5 84 6.3E-16 T 28-03-2018 CFK41_RS13985 73169de6ad0f85c9f92c3e87a6ba178c 194 Pfam PF01381 Helix-turn-helix 17 69 5.6E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CFK41_RS13985 73169de6ad0f85c9f92c3e87a6ba178c 194 SMART SM00530 16 71 6.4E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CFK41_RS07870 0a3e9e2c81186c2394b32cb31a8ac3ff 271 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS07870 0a3e9e2c81186c2394b32cb31a8ac3ff 271 Gene3D G3DSA:3.40.50.300 1 249 5.9E-67 T 28-03-2018 CFK41_RS07870 0a3e9e2c81186c2394b32cb31a8ac3ff 271 Pfam PF00005 ABC transporter 18 165 3.0E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS07870 0a3e9e2c81186c2394b32cb31a8ac3ff 271 SUPERFAMILY SSF52540 3 232 7.14E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS07870 0a3e9e2c81186c2394b32cb31a8ac3ff 271 SMART SM00382 27 213 1.2E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS02055 712d4989e74f4e0416bd46d3641c050c 419 Gene3D G3DSA:3.30.565.10 283 419 4.6E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS02055 712d4989e74f4e0416bd46d3641c050c 419 SUPERFAMILY SSF55874 291 403 1.86E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS02055 712d4989e74f4e0416bd46d3641c050c 419 Pfam PF07730 Histidine kinase 209 274 7.0E-17 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CFK41_RS06505 77577f7c2032ed55088cd3ef62306509 441 Pfam PF01551 Peptidase family M23 339 437 2.4E-22 T 28-03-2018 IPR016047 Peptidase M23 CFK41_RS06505 77577f7c2032ed55088cd3ef62306509 441 Gene3D G3DSA:1.10.287.620 29 144 1.6E-6 T 28-03-2018 CFK41_RS06505 77577f7c2032ed55088cd3ef62306509 441 Gene3D G3DSA:2.70.70.10 286 441 4.5E-39 T 28-03-2018 CFK41_RS06505 77577f7c2032ed55088cd3ef62306509 441 SUPERFAMILY SSF51261 236 441 4.5E-45 T 28-03-2018 IPR011055 Duplicated hybrid motif CFK41_RS06505 77577f7c2032ed55088cd3ef62306509 441 Gene3D G3DSA:1.20.5.50 167 285 0.001 T 28-03-2018 CFK41_RS07840 6a3d4cefa423e8605ad32e32e7e74f40 657 Gene3D G3DSA:1.50.10.20 116 351 7.7E-31 T 28-03-2018 CFK41_RS07840 6a3d4cefa423e8605ad32e32e7e74f40 657 SUPERFAMILY SSF48208 151 384 3.49E-18 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CFK41_RS07840 6a3d4cefa423e8605ad32e32e7e74f40 657 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 50 572 4.2E-101 T 28-03-2018 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 CFK41_RS14480 9c4a03d9de9e6dd37fd37adcdad3caa1 247 Pfam PF04250 Protein of unknown function (DUF429) 11 226 8.6E-33 T 28-03-2018 IPR007362 Protein of unknown function DUF429 CFK41_RS01235 ce99620dc6b2ade78f797fcf5d672b6f 312 Gene3D G3DSA:1.10.3720.10 1 294 3.2E-27 T 28-03-2018 CFK41_RS01235 ce99620dc6b2ade78f797fcf5d672b6f 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 305 2.5E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01235 ce99620dc6b2ade78f797fcf5d672b6f 312 SUPERFAMILY SSF161098 96 288 1.22E-10 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01675 3ff6d5c26a12cf1fc725cadee808c083 546 Gene3D G3DSA:2.60.40.1180 417 545 5.7E-23 T 28-03-2018 CFK41_RS01675 3ff6d5c26a12cf1fc725cadee808c083 546 SUPERFAMILY SSF51445 53 424 1.1E-90 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS01675 3ff6d5c26a12cf1fc725cadee808c083 546 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 341 536 2.5E-36 T 28-03-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 CFK41_RS01675 3ff6d5c26a12cf1fc725cadee808c083 546 Gene3D G3DSA:3.20.20.80 54 416 2.8E-98 T 28-03-2018 CFK41_RS01675 3ff6d5c26a12cf1fc725cadee808c083 546 SUPERFAMILY SSF51011 407 542 1.51E-17 T 28-03-2018 CFK41_RS01675 3ff6d5c26a12cf1fc725cadee808c083 546 SMART SM00813 341 536 1.7E-67 T 28-03-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 CFK41_RS02910 a65732994d0a4613fee899855a5855d6 311 Gene3D G3DSA:3.40.1130.10 78 304 9.9E-33 T 28-03-2018 CFK41_RS02910 a65732994d0a4613fee899855a5855d6 311 SMART SM00563 126 243 3.3E-16 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CFK41_RS02910 a65732994d0a4613fee899855a5855d6 311 Pfam PF01553 Acyltransferase 117 240 2.1E-18 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CFK41_RS02910 a65732994d0a4613fee899855a5855d6 311 SUPERFAMILY SSF69593 123 296 2.62E-33 T 28-03-2018 CFK41_RS17645 da9875a39e6b8e1d2811c1dc91e49cd7 293 SUPERFAMILY SSF51658 6 287 4.45E-40 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS17645 da9875a39e6b8e1d2811c1dc91e49cd7 293 Gene3D G3DSA:3.20.20.150 1 293 8.1E-46 T 28-03-2018 CFK41_RS17645 da9875a39e6b8e1d2811c1dc91e49cd7 293 Pfam PF01261 Xylose isomerase-like TIM barrel 50 233 1.5E-20 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS09505 38ecbfaa862eafffedafb1a5e6e6f704 199 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 17 191 6.6E-63 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CFK41_RS09505 38ecbfaa862eafffedafb1a5e6e6f704 199 Gene3D G3DSA:3.30.63.10 61 93 3.6E-23 T 28-03-2018 CFK41_RS09505 38ecbfaa862eafffedafb1a5e6e6f704 199 Hamap MF_00328 Guanylate kinase [gmk]. 13 197 33.745 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CFK41_RS09505 38ecbfaa862eafffedafb1a5e6e6f704 199 Pfam PF00625 Guanylate kinase 18 192 3.5E-38 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CFK41_RS09505 38ecbfaa862eafffedafb1a5e6e6f704 199 Gene3D G3DSA:3.40.50.300 94 194 9.1E-26 T 28-03-2018 CFK41_RS09505 38ecbfaa862eafffedafb1a5e6e6f704 199 SMART SM00072 15 197 6.4E-51 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CFK41_RS09505 38ecbfaa862eafffedafb1a5e6e6f704 199 Gene3D G3DSA:3.40.50.300 12 60 7.2E-7 T 28-03-2018 CFK41_RS09505 38ecbfaa862eafffedafb1a5e6e6f704 199 ProSitePatterns PS00856 Guanylate kinase-like signature. 49 66 - T 28-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 CFK41_RS09505 38ecbfaa862eafffedafb1a5e6e6f704 199 SUPERFAMILY SSF52540 17 193 6.92E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS15505 0025d8f2a3b518ca610e64c20c5b56db 250 Gene3D G3DSA:1.10.10.60 78 208 5.9E-9 T 28-03-2018 CFK41_RS15505 0025d8f2a3b518ca610e64c20c5b56db 250 Pfam PF00440 Bacterial regulatory proteins, tetR family 57 87 9.0E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS15505 0025d8f2a3b518ca610e64c20c5b56db 250 Gene3D G3DSA:1.10.10.60 3 77 2.2E-15 T 28-03-2018 CFK41_RS15505 0025d8f2a3b518ca610e64c20c5b56db 250 SUPERFAMILY SSF46689 34 100 1.85E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS11095 e8405d8232ad217a8feb57a9b85a0cb1 610 Gene3D G3DSA:3.40.50.300 353 610 3.7E-56 T 28-03-2018 CFK41_RS11095 e8405d8232ad217a8feb57a9b85a0cb1 610 SUPERFAMILY SSF52540 363 607 1.71E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11095 e8405d8232ad217a8feb57a9b85a0cb1 610 Pfam PF00664 ABC transporter transmembrane region 55 325 2.0E-31 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS11095 e8405d8232ad217a8feb57a9b85a0cb1 610 SUPERFAMILY SSF90123 44 350 3.53E-55 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS11095 e8405d8232ad217a8feb57a9b85a0cb1 610 Gene3D G3DSA:1.20.1560.10 34 351 1.4E-47 T 28-03-2018 CFK41_RS11095 e8405d8232ad217a8feb57a9b85a0cb1 610 Pfam PF00005 ABC transporter 389 538 4.7E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS11095 e8405d8232ad217a8feb57a9b85a0cb1 610 SMART SM00382 398 584 2.3E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS06390 fe9f0042d60533940ce16f033d6aa29a 213 SMART SM00858 45 108 5.2E-4 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CFK41_RS06390 fe9f0042d60533940ce16f033d6aa29a 213 Gene3D G3DSA:3.90.1210.10 43 109 1.1E-7 T 28-03-2018 CFK41_RS15205 889120ddb2fe225098e9e8c72acff0e2 111 SUPERFAMILY SSF54001 1 107 3.87E-27 T 28-03-2018 CFK41_RS15205 889120ddb2fe225098e9e8c72acff0e2 111 Pfam PF00877 NlpC/P60 family 2 93 6.9E-19 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CFK41_RS15205 889120ddb2fe225098e9e8c72acff0e2 111 Gene3D G3DSA:3.90.1720.10 1 109 2.2E-24 T 28-03-2018 CFK41_RS16510 f2e4c16d39e358a3bc3d12f37dc11754 324 SUPERFAMILY SSF48008 184 317 8.89E-23 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS16510 f2e4c16d39e358a3bc3d12f37dc11754 324 SMART SM00895 188 313 2.4E-15 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS16510 f2e4c16d39e358a3bc3d12f37dc11754 324 Pfam PF00392 Bacterial regulatory proteins, gntR family 116 177 2.5E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS16510 f2e4c16d39e358a3bc3d12f37dc11754 324 Pfam PF07729 FCD domain 188 312 3.2E-19 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS16510 f2e4c16d39e358a3bc3d12f37dc11754 324 SMART SM00345 119 177 6.4E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS16510 f2e4c16d39e358a3bc3d12f37dc11754 324 Gene3D G3DSA:1.20.120.530 179 324 6.6E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS16510 f2e4c16d39e358a3bc3d12f37dc11754 324 Gene3D G3DSA:1.10.10.10 121 178 2.6E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS16510 f2e4c16d39e358a3bc3d12f37dc11754 324 SUPERFAMILY SSF46785 112 190 2.64E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS16510 f2e4c16d39e358a3bc3d12f37dc11754 324 Gene3D G3DSA:1.10.1040.10 38 120 2.5E-11 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CFK41_RS16510 f2e4c16d39e358a3bc3d12f37dc11754 324 SUPERFAMILY SSF48179 39 127 4.31E-9 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CFK41_RS16510 f2e4c16d39e358a3bc3d12f37dc11754 324 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 40 122 3.6E-7 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CFK41_RS08350 223caa5cad5d3f3377175b4823c98fd4 373 ProSitePatterns PS00356 LacI-type HTH domain signature. 20 38 - T 28-03-2018 CFK41_RS08350 223caa5cad5d3f3377175b4823c98fd4 373 SMART SM00354 17 87 2.1E-18 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS08350 223caa5cad5d3f3377175b4823c98fd4 373 SUPERFAMILY SSF53822 91 329 5.69E-47 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS08350 223caa5cad5d3f3377175b4823c98fd4 373 Pfam PF13377 Periplasmic binding protein-like domain 189 355 4.9E-26 T 28-03-2018 CFK41_RS08350 223caa5cad5d3f3377175b4823c98fd4 373 Pfam PF00356 Bacterial regulatory proteins, lacI family 19 64 1.4E-14 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS08350 223caa5cad5d3f3377175b4823c98fd4 373 Gene3D G3DSA:1.10.260.40 30 69 1.9E-20 T 28-03-2018 CFK41_RS08350 223caa5cad5d3f3377175b4823c98fd4 373 SUPERFAMILY SSF47413 17 72 7.47E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS08350 223caa5cad5d3f3377175b4823c98fd4 373 Gene3D G3DSA:1.10.10.60 8 29 0.0044 T 28-03-2018 CFK41_RS08350 223caa5cad5d3f3377175b4823c98fd4 373 Gene3D G3DSA:3.40.50.2300 70 194 1.6E-25 T 28-03-2018 CFK41_RS08350 223caa5cad5d3f3377175b4823c98fd4 373 Gene3D G3DSA:3.40.50.2300 195 326 8.4E-30 T 28-03-2018 CFK41_RS02890 9aab36a1a38b95abed9ce7563a4604b5 263 SMART SM00382 36 236 4.0E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS02890 9aab36a1a38b95abed9ce7563a4604b5 263 PIRSF PIRSF039085 8 263 3.2E-117 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CFK41_RS02890 9aab36a1a38b95abed9ce7563a4604b5 263 Gene3D G3DSA:3.40.50.300 8 262 3.5E-77 T 28-03-2018 CFK41_RS02890 9aab36a1a38b95abed9ce7563a4604b5 263 Pfam PF00005 ABC transporter 27 188 4.4E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS02890 9aab36a1a38b95abed9ce7563a4604b5 263 SUPERFAMILY SSF52540 11 258 1.03E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS02890 9aab36a1a38b95abed9ce7563a4604b5 263 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS09015 aa0433f951fb5cad684ea6519be3418a 319 SUPERFAMILY SSF103481 61 154 4.18E-9 T 28-03-2018 CFK41_RS09015 aa0433f951fb5cad684ea6519be3418a 319 Pfam PF00892 EamA-like transporter family 20 153 1.8E-11 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CFK41_RS09015 aa0433f951fb5cad684ea6519be3418a 319 Pfam PF00892 EamA-like transporter family 168 299 2.3E-16 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CFK41_RS09015 aa0433f951fb5cad684ea6519be3418a 319 SUPERFAMILY SSF103481 201 306 8.5E-13 T 28-03-2018 CFK41_RS04580 cd9832a76f94806b5520b92f461b93c4 308 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 12 211 32.157 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04580 cd9832a76f94806b5520b92f461b93c4 308 Pfam PF00573 Ribosomal protein L4/L1 family 20 206 8.3E-60 T 28-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 CFK41_RS04580 cd9832a76f94806b5520b92f461b93c4 308 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 20 206 3.7E-66 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04580 cd9832a76f94806b5520b92f461b93c4 308 Gene3D G3DSA:3.40.1370.10 143 209 4.2E-10 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CFK41_RS04580 cd9832a76f94806b5520b92f461b93c4 308 Gene3D G3DSA:3.40.1370.10 5 142 3.5E-51 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CFK41_RS04580 cd9832a76f94806b5520b92f461b93c4 308 Gene3D G3DSA:3.40.10.10 217 297 1.2E-13 T 28-03-2018 IPR035451 Ada-like domain CFK41_RS04580 cd9832a76f94806b5520b92f461b93c4 308 SUPERFAMILY SSF52166 6 207 4.97E-70 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CFK41_RS04855 90e9c336808984e9dedf06cd80a0ddd0 221 PIRSF PIRSF037394 15 208 1.0E-47 T 28-03-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted CFK41_RS04855 90e9c336808984e9dedf06cd80a0ddd0 221 Pfam PF09819 ABC-type cobalt transport system, permease component 24 144 1.3E-34 T 28-03-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted CFK41_RS14815 94ad0b84820927c96b078ff8b38ea035 421 SUPERFAMILY SSF103473 13 404 4.58E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS14815 94ad0b84820927c96b078ff8b38ea035 421 Pfam PF07690 Major Facilitator Superfamily 28 338 3.2E-34 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS14815 94ad0b84820927c96b078ff8b38ea035 421 Gene3D G3DSA:1.20.1250.20 205 414 6.0E-18 T 28-03-2018 CFK41_RS14815 94ad0b84820927c96b078ff8b38ea035 421 Gene3D G3DSA:1.20.1250.20 15 204 8.0E-28 T 28-03-2018 CFK41_RS08235 4b38fedc5ca39c51b9478c8a1b2660d3 457 PIRSF PIRSF000337 3 451 2.4E-128 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CFK41_RS08235 4b38fedc5ca39c51b9478c8a1b2660d3 457 SUPERFAMILY SSF51679 4 442 7.59E-112 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CFK41_RS08235 4b38fedc5ca39c51b9478c8a1b2660d3 457 Pfam PF00296 Luciferase-like monooxygenase 24 393 6.6E-56 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CFK41_RS08235 4b38fedc5ca39c51b9478c8a1b2660d3 457 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 8 435 4.5E-143 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CFK41_RS08235 4b38fedc5ca39c51b9478c8a1b2660d3 457 Gene3D G3DSA:3.20.20.30 2 457 2.2E-106 T 28-03-2018 CFK41_RS01530 2e97977fd927e3cb93c008693e3c2189 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 294 6.2E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01530 2e97977fd927e3cb93c008693e3c2189 303 SUPERFAMILY SSF161098 18 303 1.03E-68 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01530 2e97977fd927e3cb93c008693e3c2189 303 Gene3D G3DSA:1.10.3720.10 13 291 9.9E-43 T 28-03-2018 CFK41_RS07865 c1656dd137b9ea959373a41e6e6800ae 366 Pfam PF01032 FecCD transport family 42 359 1.4E-85 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CFK41_RS07865 c1656dd137b9ea959373a41e6e6800ae 366 SUPERFAMILY SSF81345 24 359 1.44E-74 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CFK41_RS07865 c1656dd137b9ea959373a41e6e6800ae 366 Gene3D G3DSA:1.10.3470.10 25 366 2.1E-71 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CFK41_RS05325 51da5a63eec9b517a9b9cdf9ed87f043 763 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 13 712 23.92 T 28-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CFK41_RS05325 51da5a63eec9b517a9b9cdf9ed87f043 763 Pfam PF03030 Inorganic H+ pyrophosphatase 24 707 6.4E-236 T 28-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CFK41_RS05325 51da5a63eec9b517a9b9cdf9ed87f043 763 PIRSF PIRSF001265 8 719 1.2E-243 T 28-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CFK41_RS05325 51da5a63eec9b517a9b9cdf9ed87f043 763 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 14 712 3.2E-205 T 28-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CFK41_RS04575 23540892e400b5c8483395248ac786dd 226 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 13 219 39.653 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04575 23540892e400b5c8483395248ac786dd 226 Gene3D G3DSA:4.10.960.10 69 177 9.6E-37 T 28-03-2018 CFK41_RS04575 23540892e400b5c8483395248ac786dd 226 Pfam PF00297 Ribosomal protein L3 107 190 2.1E-14 T 28-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS04575 23540892e400b5c8483395248ac786dd 226 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 15 216 4.0E-86 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04575 23540892e400b5c8483395248ac786dd 226 SUPERFAMILY SSF50447 13 224 1.15E-80 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CFK41_RS04575 23540892e400b5c8483395248ac786dd 226 ProSitePatterns PS00474 Ribosomal protein L3 signature. 113 136 - T 28-03-2018 IPR019926 Ribosomal protein L3, conserved site CFK41_RS15585 f0b28a2ef2348bb432610a563d655cb1 341 Gene3D G3DSA:3.40.190.10 147 340 1.4E-19 T 28-03-2018 CFK41_RS15585 f0b28a2ef2348bb432610a563d655cb1 341 SUPERFAMILY SSF53850 39 260 2.09E-28 T 28-03-2018 CFK41_RS15585 f0b28a2ef2348bb432610a563d655cb1 341 Gene3D G3DSA:3.40.190.10 37 142 2.2E-14 T 28-03-2018 CFK41_RS15585 f0b28a2ef2348bb432610a563d655cb1 341 Pfam PF09084 NMT1/THI5 like 52 207 3.5E-16 T 28-03-2018 IPR015168 SsuA/THI5-like CFK41_RS14380 9e975d7d7cfcafee675edf1e3670df7a 336 Gene3D G3DSA:3.20.20.140 2 336 1.4E-73 T 28-03-2018 CFK41_RS14380 9e975d7d7cfcafee675edf1e3670df7a 336 Pfam PF00962 Adenosine/AMP deaminase 12 327 2.8E-58 T 28-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 CFK41_RS14380 9e975d7d7cfcafee675edf1e3670df7a 336 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 12 329 1.4E-102 T 28-03-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 CFK41_RS14380 9e975d7d7cfcafee675edf1e3670df7a 336 Hamap MF_01962 Adenine deaminase. 8 319 63.948 T 28-03-2018 IPR028892 Adenine deaminase type 2 GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 CFK41_RS14380 9e975d7d7cfcafee675edf1e3670df7a 336 SUPERFAMILY SSF51556 5 333 8.83E-75 T 28-03-2018 IPR032466 Metal-dependent hydrolase CFK41_RS03360 f397f7fb80e37a013bdf8cd8b22a5bc0 469 PRINTS PR00738 Glycosyl hydrolase family 20 signature 85 102 2.8E-40 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CFK41_RS03360 f397f7fb80e37a013bdf8cd8b22a5bc0 469 PRINTS PR00738 Glycosyl hydrolase family 20 signature 259 272 2.8E-40 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CFK41_RS03360 f397f7fb80e37a013bdf8cd8b22a5bc0 469 PRINTS PR00738 Glycosyl hydrolase family 20 signature 421 438 2.8E-40 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CFK41_RS03360 f397f7fb80e37a013bdf8cd8b22a5bc0 469 PRINTS PR00738 Glycosyl hydrolase family 20 signature 237 255 2.8E-40 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CFK41_RS03360 f397f7fb80e37a013bdf8cd8b22a5bc0 469 PRINTS PR00738 Glycosyl hydrolase family 20 signature 403 419 2.8E-40 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CFK41_RS03360 f397f7fb80e37a013bdf8cd8b22a5bc0 469 PRINTS PR00738 Glycosyl hydrolase family 20 signature 114 135 2.8E-40 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CFK41_RS03360 f397f7fb80e37a013bdf8cd8b22a5bc0 469 PRINTS PR00738 Glycosyl hydrolase family 20 signature 52 72 2.8E-40 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CFK41_RS03360 f397f7fb80e37a013bdf8cd8b22a5bc0 469 PRINTS PR00738 Glycosyl hydrolase family 20 signature 189 206 2.8E-40 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CFK41_RS03360 f397f7fb80e37a013bdf8cd8b22a5bc0 469 SUPERFAMILY SSF55545 5 90 4.88E-10 T 28-03-2018 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CFK41_RS03360 f397f7fb80e37a013bdf8cd8b22a5bc0 469 PIRSF PIRSF001093 170 469 6.5E-47 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CFK41_RS03360 f397f7fb80e37a013bdf8cd8b22a5bc0 469 PIRSF PIRSF001093 36 158 6.6E-31 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CFK41_RS03360 f397f7fb80e37a013bdf8cd8b22a5bc0 469 Gene3D G3DSA:3.20.20.80 81 469 1.8E-128 T 28-03-2018 CFK41_RS03360 f397f7fb80e37a013bdf8cd8b22a5bc0 469 Gene3D G3DSA:3.30.379.10 29 80 5.2E-8 T 28-03-2018 CFK41_RS03360 f397f7fb80e37a013bdf8cd8b22a5bc0 469 SUPERFAMILY SSF51445 92 451 2.23E-114 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS03360 f397f7fb80e37a013bdf8cd8b22a5bc0 469 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 92 438 8.1E-111 T 28-03-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CFK41_RS14225 f8ce5f13a20e64170d8bcc63fe942031 303 SUPERFAMILY SSF51735 87 266 1.41E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS14225 f8ce5f13a20e64170d8bcc63fe942031 303 Gene3D G3DSA:3.40.50.720 97 267 1.6E-50 T 28-03-2018 CFK41_RS14225 f8ce5f13a20e64170d8bcc63fe942031 303 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 91 266 4.7E-48 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CFK41_RS14225 f8ce5f13a20e64170d8bcc63fe942031 303 Gene3D G3DSA:3.40.50.720 3 96 1.6E-14 T 28-03-2018 CFK41_RS01820 9a97bfba9a15c47e06f2a7264031f64e 497 Gene3D G3DSA:3.20.20.150 23 370 8.1E-9 T 28-03-2018 CFK41_RS02845 622479f1545b7eaac95c4ddc5a49d53f 169 Pfam PF04306 Protein of unknown function (DUF456) 26 162 6.3E-26 T 28-03-2018 IPR007403 Protein of unknown function DUF456 CFK41_RS12450 9ce139128eb8c2cf185cd60062966d64 139 Gene3D G3DSA:3.30.1050.10 30 124 1.0E-6 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CFK41_RS12450 9ce139128eb8c2cf185cd60062966d64 139 SUPERFAMILY SSF55718 67 120 5.89E-7 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CFK41_RS02920 57de01498c71d1005d7b010b8eb74810 191 Gene3D G3DSA:3.40.50.1240 1 190 1.7E-30 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CFK41_RS02920 57de01498c71d1005d7b010b8eb74810 191 SUPERFAMILY SSF53254 2 182 4.58E-31 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CFK41_RS02920 57de01498c71d1005d7b010b8eb74810 191 SMART SM00855 1 156 5.5E-10 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CFK41_RS02920 57de01498c71d1005d7b010b8eb74810 191 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 2 185 1.7E-29 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CFK41_RS12880 6962d33da8510f262f5a6b0f55f6358a 378 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 5 373 7.6E-122 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CFK41_RS12880 6962d33da8510f262f5a6b0f55f6358a 378 SUPERFAMILY SSF53383 21 374 5.85E-98 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS12880 6962d33da8510f262f5a6b0f55f6358a 378 PIRSF PIRSF001434 1 377 2.3E-127 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CFK41_RS12880 6962d33da8510f262f5a6b0f55f6358a 378 Gene3D G3DSA:3.90.1150.10 243 378 1.3E-42 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS12880 6962d33da8510f262f5a6b0f55f6358a 378 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 184 198 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CFK41_RS12880 6962d33da8510f262f5a6b0f55f6358a 378 Gene3D G3DSA:3.40.640.10 1 242 2.0E-47 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS06575 4d4390b53c6f537a0e1ce044d62d2fd6 294 SUPERFAMILY SSF52540 30 282 1.21E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS06575 4d4390b53c6f537a0e1ce044d62d2fd6 294 Gene3D G3DSA:3.40.50.300 26 294 9.5E-63 T 28-03-2018 CFK41_RS06575 4d4390b53c6f537a0e1ce044d62d2fd6 294 SMART SM00382 65 260 1.5E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS06575 4d4390b53c6f537a0e1ce044d62d2fd6 294 Pfam PF00005 ABC transporter 57 210 2.0E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS06575 4d4390b53c6f537a0e1ce044d62d2fd6 294 ProSitePatterns PS00211 ABC transporters family signature. 183 197 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS10790 f86a4aec48f175325e81b8ef1fdc4382 358 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 95 114 1.9E-25 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CFK41_RS10790 f86a4aec48f175325e81b8ef1fdc4382 358 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 226 236 1.9E-25 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CFK41_RS10790 f86a4aec48f175325e81b8ef1fdc4382 358 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 172 193 1.9E-25 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CFK41_RS10790 f86a4aec48f175325e81b8ef1fdc4382 358 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 44 60 1.9E-25 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CFK41_RS10790 f86a4aec48f175325e81b8ef1fdc4382 358 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 33 356 2.5E-73 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CFK41_RS10790 f86a4aec48f175325e81b8ef1fdc4382 358 Gene3D G3DSA:3.40.50.620 7 184 1.8E-38 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS10790 f86a4aec48f175325e81b8ef1fdc4382 358 Gene3D G3DSA:3.40.50.620 185 224 7.2E-12 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS10790 f86a4aec48f175325e81b8ef1fdc4382 358 SUPERFAMILY SSF52374 33 356 1.33E-75 T 28-03-2018 CFK41_RS10790 f86a4aec48f175325e81b8ef1fdc4382 358 Pfam PF00579 tRNA synthetases class I (W and Y) 32 311 8.6E-56 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS10790 f86a4aec48f175325e81b8ef1fdc4382 358 Gene3D G3DSA:1.10.240.10 225 352 3.5E-29 T 28-03-2018 CFK41_RS10790 f86a4aec48f175325e81b8ef1fdc4382 358 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 40 49 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CFK41_RS13730 2d2a1df2ca847c4abcf079a53660e2c6 386 Pfam PF07730 Histidine kinase 202 266 2.9E-18 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CFK41_RS13730 2d2a1df2ca847c4abcf079a53660e2c6 386 SUPERFAMILY SSF55874 274 381 1.51E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS13730 2d2a1df2ca847c4abcf079a53660e2c6 386 Gene3D G3DSA:3.30.565.10 249 381 7.3E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS02270 cce85f88ac9b7b650877ec8ceab84da3 438 SUPERFAMILY SSF54211 5 157 9.87E-24 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CFK41_RS02270 cce85f88ac9b7b650877ec8ceab84da3 438 Pfam PF10509 Galactokinase galactose-binding signature 6 39 1.6E-9 T 28-03-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CFK41_RS02270 cce85f88ac9b7b650877ec8ceab84da3 438 Gene3D G3DSA:3.30.70.890 211 431 1.6E-19 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CFK41_RS02270 cce85f88ac9b7b650877ec8ceab84da3 438 PRINTS PR00473 Galactokinase signature 77 88 1.1E-8 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CFK41_RS02270 cce85f88ac9b7b650877ec8ceab84da3 438 PRINTS PR00473 Galactokinase signature 97 115 1.1E-8 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CFK41_RS02270 cce85f88ac9b7b650877ec8ceab84da3 438 PRINTS PR00473 Galactokinase signature 12 30 1.1E-8 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CFK41_RS02270 cce85f88ac9b7b650877ec8ceab84da3 438 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 106 117 - T 28-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 CFK41_RS02270 cce85f88ac9b7b650877ec8ceab84da3 438 SUPERFAMILY SSF55060 307 411 1.8E-13 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CFK41_RS02270 cce85f88ac9b7b650877ec8ceab84da3 438 SUPERFAMILY SSF55060 204 225 1.8E-13 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CFK41_RS02270 cce85f88ac9b7b650877ec8ceab84da3 438 PRINTS PR00959 Mevalonate kinase family signature 10 34 2.2E-19 T 28-03-2018 CFK41_RS02270 cce85f88ac9b7b650877ec8ceab84da3 438 PRINTS PR00959 Mevalonate kinase family signature 377 394 2.2E-19 T 28-03-2018 CFK41_RS02270 cce85f88ac9b7b650877ec8ceab84da3 438 PRINTS PR00959 Mevalonate kinase family signature 104 126 2.2E-19 T 28-03-2018 CFK41_RS02270 cce85f88ac9b7b650877ec8ceab84da3 438 Pfam PF08544 GHMP kinases C terminal 332 409 6.2E-6 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CFK41_RS02270 cce85f88ac9b7b650877ec8ceab84da3 438 Gene3D G3DSA:3.30.230.10 2 210 2.1E-34 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CFK41_RS02270 cce85f88ac9b7b650877ec8ceab84da3 438 Pfam PF00288 GHMP kinases N terminal domain 99 135 1.5E-8 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CFK41_RS15295 8b55d147a270cd978bf17d0cb1b04e8a 362 Pfam PF07663 Sorbitol phosphotransferase enzyme II C-terminus 270 361 9.3E-44 T 28-03-2018 IPR011638 Sorbitol phosphotransferase enzyme II, C-terminal GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CFK41_RS15295 8b55d147a270cd978bf17d0cb1b04e8a 362 Pfam PF03612 Sorbitol phosphotransferase enzyme II N-terminus 5 215 7.6E-58 T 28-03-2018 IPR011618 Sorbitol phosphotransferase enzyme II, N-terminal GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CFK41_RS03820 67567559ed558bf2ccd38be290d3073b 179 Pfam PF01899 Na+/H+ ion antiporter subunit 17 163 1.8E-28 T 28-03-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 CFK41_RS08000 f4a824f71a0ff2153d7a9653e0b405aa 462 PIRSF PIRSF000806 1 458 1.6E-126 T 28-03-2018 IPR016267 UTP--glucose-1-phosphate uridylyltransferase GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817|Reactome: R-HSA-173599|Reactome: R-HSA-3322077 CFK41_RS08000 f4a824f71a0ff2153d7a9653e0b405aa 462 Gene3D G3DSA:3.90.550.10 1 361 2.5E-90 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS08000 f4a824f71a0ff2153d7a9653e0b405aa 462 Gene3D G3DSA:2.160.10.10 362 458 4.7E-25 T 28-03-2018 CFK41_RS08000 f4a824f71a0ff2153d7a9653e0b405aa 462 SUPERFAMILY SSF53448 16 441 3.94E-75 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS08000 f4a824f71a0ff2153d7a9653e0b405aa 462 Pfam PF01704 UTP--glucose-1-phosphate uridylyltransferase 37 436 1.2E-117 T 28-03-2018 IPR002618 UDPGP family GO:0008152|GO:0070569 CFK41_RS02415 a99fb80aae4dc693db6ed2d057257687 262 Pfam PF00005 ABC transporter 33 170 5.7E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS02415 a99fb80aae4dc693db6ed2d057257687 262 SUPERFAMILY SSF52540 13 228 4.8E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS02415 a99fb80aae4dc693db6ed2d057257687 262 Gene3D G3DSA:3.40.50.300 7 238 3.2E-60 T 28-03-2018 CFK41_RS02415 a99fb80aae4dc693db6ed2d057257687 262 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS02415 a99fb80aae4dc693db6ed2d057257687 262 SMART SM00382 40 229 2.3E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS09450 0fa79dc1811dc7c80ef6876add88293e 277 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 55 68 - T 28-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CFK41_RS09450 0fa79dc1811dc7c80ef6876add88293e 277 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 21 269 31.33 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CFK41_RS09450 0fa79dc1811dc7c80ef6876add88293e 277 Pfam PF00290 Tryptophan synthase alpha chain 17 263 2.9E-69 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CFK41_RS09450 0fa79dc1811dc7c80ef6876add88293e 277 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 18 266 2.8E-66 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CFK41_RS09450 0fa79dc1811dc7c80ef6876add88293e 277 Gene3D G3DSA:3.20.20.70 9 277 8.6E-73 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS09450 0fa79dc1811dc7c80ef6876add88293e 277 SUPERFAMILY SSF51366 10 266 3.58E-75 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CFK41_RS12835 401cd579a40343842fd1f2f300398f85 487 SUPERFAMILY SSF53474 86 199 2.87E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS12835 401cd579a40343842fd1f2f300398f85 487 SUPERFAMILY SSF53474 340 394 2.87E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS12835 401cd579a40343842fd1f2f300398f85 487 Gene3D G3DSA:3.40.50.1820 71 406 1.5E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS12835 401cd579a40343842fd1f2f300398f85 487 Pfam PF00561 alpha/beta hydrolase fold 89 221 1.6E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CFK41_RS12835 401cd579a40343842fd1f2f300398f85 487 Pfam PF08386 TAP-like protein 339 394 1.5E-4 T 28-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal CFK41_RS12975 3848c8f66f847044c3c7d0a9da0044f1 339 Gene3D G3DSA:3.40.630.30 188 333 1.6E-18 T 28-03-2018 CFK41_RS12975 3848c8f66f847044c3c7d0a9da0044f1 339 SUPERFAMILY SSF55729 12 121 1.92E-12 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS12975 3848c8f66f847044c3c7d0a9da0044f1 339 SUPERFAMILY SSF55729 152 328 3.44E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS12975 3848c8f66f847044c3c7d0a9da0044f1 339 Pfam PF00583 Acetyltransferase (GNAT) family 209 319 2.0E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS12975 3848c8f66f847044c3c7d0a9da0044f1 339 Gene3D G3DSA:3.40.630.30 9 175 4.1E-12 T 28-03-2018 CFK41_RS05415 b29e6e6f1a5935052d8c1efd03ef0e7a 280 SUPERFAMILY SSF51658 17 277 5.8E-33 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS05415 b29e6e6f1a5935052d8c1efd03ef0e7a 280 Pfam PF01261 Xylose isomerase-like TIM barrel 24 201 2.3E-12 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS05415 b29e6e6f1a5935052d8c1efd03ef0e7a 280 Gene3D G3DSA:3.20.20.150 2 278 1.4E-34 T 28-03-2018 CFK41_RS11420 e3e14a9ded76f1bd5698045ef369cb16 314 SUPERFAMILY SSF56219 264 311 3.14E-29 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS11420 e3e14a9ded76f1bd5698045ef369cb16 314 SUPERFAMILY SSF56219 5 190 3.14E-29 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS11420 e3e14a9ded76f1bd5698045ef369cb16 314 Gene3D G3DSA:3.60.10.10 2 311 1.7E-29 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS11420 e3e14a9ded76f1bd5698045ef369cb16 314 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 23 303 2.2E-15 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS05320 d75dff7f2999486f3cac9d80040038d3 104 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 7 91 1.1E-21 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CFK41_RS05320 d75dff7f2999486f3cac9d80040038d3 104 SUPERFAMILY SSF55248 8 94 2.22E-22 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CFK41_RS05320 d75dff7f2999486f3cac9d80040038d3 104 Gene3D G3DSA:3.30.1360.20 6 103 1.5E-22 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CFK41_RS14775 24cf5e44546210a274f65d3e8f84dfde 317 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 160 182 1.1E-8 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CFK41_RS14775 24cf5e44546210a274f65d3e8f84dfde 317 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 23 40 1.1E-8 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CFK41_RS14775 24cf5e44546210a274f65d3e8f84dfde 317 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 274 292 1.1E-8 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CFK41_RS14775 24cf5e44546210a274f65d3e8f84dfde 317 Gene3D G3DSA:2.120.10.30 8 312 7.0E-32 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CFK41_RS14775 24cf5e44546210a274f65d3e8f84dfde 317 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 22 292 1.5E-48 T 28-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region CFK41_RS14775 24cf5e44546210a274f65d3e8f84dfde 317 SUPERFAMILY SSF63829 5 304 6.1E-57 T 28-03-2018 CFK41_RS14550 2307a5bbb21552b4f363486371ec1f3c 302 Pfam PF00701 Dihydrodipicolinate synthetase family 12 295 1.3E-38 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS14550 2307a5bbb21552b4f363486371ec1f3c 302 Gene3D G3DSA:3.20.20.70 2 301 8.4E-63 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS14550 2307a5bbb21552b4f363486371ec1f3c 302 PIRSF PIRSF001365 8 302 9.1E-51 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS14550 2307a5bbb21552b4f363486371ec1f3c 302 SUPERFAMILY SSF51569 10 299 1.26E-56 T 28-03-2018 CFK41_RS14550 2307a5bbb21552b4f363486371ec1f3c 302 SMART SM01130 10 299 3.5E-47 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CFK41_RS10485 b60bbef875111657cde60ccd167a4e23 169 Pfam PF11377 Protein of unknown function (DUF3180) 9 155 2.5E-25 T 28-03-2018 IPR021517 Protein of unknown function DUF3180 CFK41_RS11260 6780d11d5a9b06cdfc53b2cda35e0afb 294 SUPERFAMILY SSF89550 12 91 2.09E-46 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CFK41_RS11260 6780d11d5a9b06cdfc53b2cda35e0afb 294 SUPERFAMILY SSF89550 175 274 2.09E-46 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CFK41_RS11260 6780d11d5a9b06cdfc53b2cda35e0afb 294 SMART SM00481 13 78 8.9E-18 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CFK41_RS11260 6780d11d5a9b06cdfc53b2cda35e0afb 294 Gene3D G3DSA:3.20.20.140 10 286 8.9E-48 T 28-03-2018 CFK41_RS11260 6780d11d5a9b06cdfc53b2cda35e0afb 294 Pfam PF02811 PHP domain 14 89 1.2E-9 T 28-03-2018 IPR004013 PHP domain GO:0003824 CFK41_RS14490 1ae145f251a9ecd87498807c9943e07e 76 Pfam PF03577 Peptidase family C69 1 63 1.0E-10 T 28-03-2018 IPR005322 Peptidase C69, dipeptidase A GO:0006508|GO:0016805 CFK41_RS13495 c23a2c34d8bda5987768785744fcfa22 181 SUPERFAMILY SSF55729 41 168 5.87E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS13495 c23a2c34d8bda5987768785744fcfa22 181 Pfam PF13302 Acetyltransferase (GNAT) domain 47 159 5.7E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS13495 c23a2c34d8bda5987768785744fcfa22 181 Gene3D G3DSA:3.40.630.30 3 181 2.2E-19 T 28-03-2018 CFK41_RS08900 7c27e12a5107c3e3ec73532c52cb427a 920 SUPERFAMILY SSF82866 124 334 3.79E-31 T 28-03-2018 CFK41_RS08900 7c27e12a5107c3e3ec73532c52cb427a 920 Gene3D G3DSA:1.20.1640.10 486 704 3.0E-30 T 28-03-2018 CFK41_RS08900 7c27e12a5107c3e3ec73532c52cb427a 920 Gene3D G3DSA:1.20.1640.10 77 343 1.2E-33 T 28-03-2018 CFK41_RS08900 7c27e12a5107c3e3ec73532c52cb427a 920 SUPERFAMILY SSF82866 468 706 7.06E-29 T 28-03-2018 CFK41_RS08900 7c27e12a5107c3e3ec73532c52cb427a 920 Pfam PF03176 MMPL family 447 710 1.2E-32 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CFK41_RS08900 7c27e12a5107c3e3ec73532c52cb427a 920 Pfam PF03176 MMPL family 46 375 2.2E-60 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CFK41_RS01540 b7f6a73198230ba8aac399379ce8c4ec 436 Gene3D G3DSA:3.40.190.10 232 371 2.0E-7 T 28-03-2018 CFK41_RS01540 b7f6a73198230ba8aac399379ce8c4ec 436 SUPERFAMILY SSF53850 64 433 2.74E-60 T 28-03-2018 CFK41_RS01540 b7f6a73198230ba8aac399379ce8c4ec 436 Pfam PF13416 Bacterial extracellular solute-binding protein 69 371 2.2E-33 T 28-03-2018 CFK41_RS01540 b7f6a73198230ba8aac399379ce8c4ec 436 Gene3D G3DSA:3.40.190.10 55 231 2.0E-29 T 28-03-2018 CFK41_RS01155 87bd358c7e40766fcc18d9834b8251f2 283 SUPERFAMILY SSF63829 12 274 1.9E-56 T 28-03-2018 CFK41_RS01155 87bd358c7e40766fcc18d9834b8251f2 283 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 14 250 1.0E-61 T 28-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region CFK41_RS01155 87bd358c7e40766fcc18d9834b8251f2 283 Gene3D G3DSA:2.120.10.30 1 281 1.2E-31 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CFK41_RS01155 87bd358c7e40766fcc18d9834b8251f2 283 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 151 171 2.2E-29 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CFK41_RS01155 87bd358c7e40766fcc18d9834b8251f2 283 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 14 31 2.2E-29 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CFK41_RS01155 87bd358c7e40766fcc18d9834b8251f2 283 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 128 150 2.2E-29 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CFK41_RS01155 87bd358c7e40766fcc18d9834b8251f2 283 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 232 250 2.2E-29 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CFK41_RS01155 87bd358c7e40766fcc18d9834b8251f2 283 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 87 108 2.2E-29 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CFK41_RS01155 87bd358c7e40766fcc18d9834b8251f2 283 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 190 207 2.2E-29 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CFK41_RS15645 917848c73e9c74e8edd6b9b9afe0d78e 538 Gene3D G3DSA:3.40.710.10 34 410 5.9E-66 T 28-03-2018 CFK41_RS15645 917848c73e9c74e8edd6b9b9afe0d78e 538 SUPERFAMILY SSF56601 32 411 1.94E-64 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CFK41_RS15645 917848c73e9c74e8edd6b9b9afe0d78e 538 Pfam PF00144 Beta-lactamase 37 395 6.8E-55 T 28-03-2018 IPR001466 Beta-lactamase-related CFK41_RS06195 5af8c11aaa36b589ff5fd12c832ddbd4 375 PIRSF PIRSF000390 1 375 2.8E-111 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CFK41_RS06195 5af8c11aaa36b589ff5fd12c832ddbd4 375 SUPERFAMILY SSF53383 2 373 1.81E-109 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS06195 5af8c11aaa36b589ff5fd12c832ddbd4 375 Gene3D G3DSA:3.40.640.10 1 245 4.8E-48 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS06195 5af8c11aaa36b589ff5fd12c832ddbd4 375 TIGRFAM TIGR03588 PseC: UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase 2 371 4.5E-130 T 28-03-2018 IPR020026 UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase CFK41_RS06195 5af8c11aaa36b589ff5fd12c832ddbd4 375 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 9 368 1.3E-118 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CFK41_RS06195 5af8c11aaa36b589ff5fd12c832ddbd4 375 Gene3D G3DSA:3.90.1150.10 246 375 3.8E-41 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS02565 fb88cd68a6d9b9ed0502dd45474447f4 265 Pfam PF04203 Sortase family 124 258 3.8E-13 T 28-03-2018 IPR005754 Sortase family CFK41_RS02565 fb88cd68a6d9b9ed0502dd45474447f4 265 Gene3D G3DSA:2.40.260.10 60 265 1.5E-24 T 28-03-2018 IPR023365 Sortase domain CFK41_RS02565 fb88cd68a6d9b9ed0502dd45474447f4 265 SUPERFAMILY SSF63817 114 245 5.1E-13 T 28-03-2018 IPR023365 Sortase domain CFK41_RS05615 357ae4a0ccca7fadcd89f8ffc125569e 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 308 2.7E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS05615 357ae4a0ccca7fadcd89f8ffc125569e 316 SUPERFAMILY SSF161098 81 307 1.07E-62 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS05615 357ae4a0ccca7fadcd89f8ffc125569e 316 Gene3D G3DSA:1.10.3720.10 89 316 6.1E-47 T 28-03-2018 CFK41_RS05615 357ae4a0ccca7fadcd89f8ffc125569e 316 Gene3D G3DSA:1.20.58.370 24 65 3.0E-4 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CFK41_RS11695 75e762b6549da23b1ad47e81bdfd3741 133 Gene3D G3DSA:1.25.40.10 14 132 5.4E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CFK41_RS15325 c1ca2620bf40426088cd935d6e5913f9 184 Gene3D G3DSA:3.40.930.10 15 154 4.0E-28 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CFK41_RS15325 c1ca2620bf40426088cd935d6e5913f9 184 SUPERFAMILY SSF55804 16 152 2.49E-29 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CFK41_RS15325 c1ca2620bf40426088cd935d6e5913f9 184 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 18 152 5.7E-26 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CFK41_RS01365 0a4bca83a80fd54a09bff11b5dc20087 310 SUPERFAMILY SSF161098 72 297 3.27E-57 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01365 0a4bca83a80fd54a09bff11b5dc20087 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 303 1.4E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01365 0a4bca83a80fd54a09bff11b5dc20087 310 Gene3D G3DSA:1.10.3720.10 32 310 1.1E-46 T 28-03-2018 CFK41_RS10000 89056e4e74c4d476af0e685a1b7425e1 239 Gene3D G3DSA:3.40.50.880 11 239 6.9E-29 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS10000 89056e4e74c4d476af0e685a1b7425e1 239 SUPERFAMILY SSF52317 14 236 2.52E-11 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS10000 89056e4e74c4d476af0e685a1b7425e1 239 Pfam PF03575 Peptidase family S51 14 228 2.5E-19 T 28-03-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 CFK41_RS16030 7bf2f674c4cf22153752648bdd57f250 329 SUPERFAMILY SSF51430 1 322 1.7E-102 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS16030 7bf2f674c4cf22153752648bdd57f250 329 Pfam PF00248 Aldo/keto reductase family 15 314 3.3E-73 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS16030 7bf2f674c4cf22153752648bdd57f250 329 PRINTS PR00069 Aldo-keto reductase signature 144 161 1.0E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS16030 7bf2f674c4cf22153752648bdd57f250 329 PRINTS PR00069 Aldo-keto reductase signature 47 71 1.0E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS16030 7bf2f674c4cf22153752648bdd57f250 329 PRINTS PR00069 Aldo-keto reductase signature 113 131 1.0E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS16030 7bf2f674c4cf22153752648bdd57f250 329 Gene3D G3DSA:3.20.20.100 3 319 4.6E-97 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS10080 41c87d603ee37703fbf019cbcdf718c3 605 Pfam PF06418 CTP synthase N-terminus 35 298 1.5E-122 T 28-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CFK41_RS10080 41c87d603ee37703fbf019cbcdf718c3 605 TIGRFAM TIGR00337 PyrG: CTP synthase 34 568 3.1E-225 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CFK41_RS10080 41c87d603ee37703fbf019cbcdf718c3 605 Hamap MF_01227 CTP synthase [pyrG]. 34 573 49.054 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CFK41_RS10080 41c87d603ee37703fbf019cbcdf718c3 605 Pfam PF00117 Glutamine amidotransferase class-I 333 566 3.6E-42 T 28-03-2018 IPR017926 Glutamine amidotransferase CFK41_RS10080 41c87d603ee37703fbf019cbcdf718c3 605 Gene3D G3DSA:3.40.50.300 24 317 5.3E-128 T 28-03-2018 CFK41_RS10080 41c87d603ee37703fbf019cbcdf718c3 605 Gene3D G3DSA:3.40.50.880 318 576 3.6E-60 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS10080 41c87d603ee37703fbf019cbcdf718c3 605 SUPERFAMILY SSF52317 321 574 5.81E-69 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS10080 41c87d603ee37703fbf019cbcdf718c3 605 SUPERFAMILY SSF52540 34 298 7.97E-117 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS08885 d6eab686448055e50df407d08fb93290 573 Gene3D G3DSA:3.30.1490.100 277 386 1.0E-4 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CFK41_RS08885 d6eab686448055e50df407d08fb93290 573 Pfam PF00817 impB/mucB/samB family 47 173 8.0E-10 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CFK41_RS08885 d6eab686448055e50df407d08fb93290 573 SUPERFAMILY SSF56672 48 270 7.41E-27 T 28-03-2018 CFK41_RS08885 d6eab686448055e50df407d08fb93290 573 Gene3D G3DSA:1.10.150.20 181 276 7.0E-14 T 28-03-2018 CFK41_RS10180 ca7958e9373cbdc910f8f914661af462 317 Gene3D G3DSA:3.30.420.150 122 312 5.9E-51 T 28-03-2018 CFK41_RS10180 ca7958e9373cbdc910f8f914661af462 317 SUPERFAMILY SSF53067 5 129 3.08E-32 T 28-03-2018 CFK41_RS10180 ca7958e9373cbdc910f8f914661af462 317 SUPERFAMILY SSF53067 135 315 2.37E-34 T 28-03-2018 CFK41_RS10180 ca7958e9373cbdc910f8f914661af462 317 Gene3D G3DSA:3.30.420.40 1 121 7.9E-46 T 28-03-2018 CFK41_RS10180 ca7958e9373cbdc910f8f914661af462 317 Pfam PF02541 Ppx/GppA phosphatase family 22 310 3.0E-55 T 28-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 CFK41_RS05405 7d7f23469db9ac8a8c3da54b12290248 502 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 443 1.4E-129 T 28-03-2018 IPR002823 Protein of unknown function DUF112, transmembrane CFK41_RS03830 e894a0f5be2f6d5dca1d4a6f0222a8f5 197 Pfam PF03334 Na+/H+ antiporter subunit 11 89 1.3E-16 T 28-03-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 CFK41_RS02460 93eed353f83eddd7fb3376e721cc7a89 334 Pfam PF12831 FAD dependent oxidoreductase 9 160 1.5E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS04760 d3fcf4459e9aba5353eb5e7f53da17a8 213 PIRSF PIRSF001357 2 213 7.9E-73 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CFK41_RS04760 d3fcf4459e9aba5353eb5e7f53da17a8 213 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 1 213 32.73 T 28-03-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 CFK41_RS04760 d3fcf4459e9aba5353eb5e7f53da17a8 213 SUPERFAMILY SSF51569 4 211 5.55E-77 T 28-03-2018 CFK41_RS04760 d3fcf4459e9aba5353eb5e7f53da17a8 213 Gene3D G3DSA:3.20.20.70 2 212 2.7E-89 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS04760 d3fcf4459e9aba5353eb5e7f53da17a8 213 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 4 209 2.2E-77 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CFK41_RS04760 d3fcf4459e9aba5353eb5e7f53da17a8 213 SMART SM01133 2 213 2.6E-86 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CFK41_RS04760 d3fcf4459e9aba5353eb5e7f53da17a8 213 Pfam PF01791 DeoC/LacD family aldolase 7 208 1.6E-22 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CFK41_RS10570 50fcd450ffb4d9c134011586a1f168b4 379 SUPERFAMILY SSF53822 92 366 1.04E-48 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS10570 50fcd450ffb4d9c134011586a1f168b4 379 Gene3D G3DSA:3.40.50.2300 89 201 1.6E-17 T 28-03-2018 CFK41_RS10570 50fcd450ffb4d9c134011586a1f168b4 379 Pfam PF13377 Periplasmic binding protein-like domain 203 362 7.8E-36 T 28-03-2018 CFK41_RS10570 50fcd450ffb4d9c134011586a1f168b4 379 Gene3D G3DSA:1.10.260.40 25 88 7.9E-5 T 28-03-2018 CFK41_RS10570 50fcd450ffb4d9c134011586a1f168b4 379 Gene3D G3DSA:3.40.50.2300 202 365 4.3E-41 T 28-03-2018 CFK41_RS17520 7a6e8cd958ec24b440538c4461b20f48 123 Gene3D G3DSA:3.40.30.10 1 107 9.8E-4 T 28-03-2018 CFK41_RS17520 7a6e8cd958ec24b440538c4461b20f48 123 SUPERFAMILY SSF52833 1 58 9.84E-5 T 28-03-2018 IPR012336 Thioredoxin-like fold CFK41_RS13365 c8641ec25e059dba26ac3124e4033dfc 338 Gene3D G3DSA:3.40.50.620 153 295 8.2E-25 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS13365 c8641ec25e059dba26ac3124e4033dfc 338 Pfam PF02698 DUF218 domain 160 306 3.7E-24 T 28-03-2018 IPR003848 Domain of unknown function DUF218 CFK41_RS10380 cb2ea63be29f43096b85d9d3c8a10689 137 SUPERFAMILY SSF81330 9 122 5.75E-25 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CFK41_RS10380 cb2ea63be29f43096b85d9d3c8a10689 137 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 2 129 3.3E-27 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CFK41_RS10380 cb2ea63be29f43096b85d9d3c8a10689 137 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 126 3.0E-35 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CFK41_RS13700 a1c73782bfb7e7b52a6699c99708d459 319 Pfam PF01758 Sodium Bile acid symporter family 46 190 4.9E-6 T 28-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 CFK41_RS16255 55704c56865e6a3918f57a9842f69b62 580 Pfam PF00474 Sodium:solute symporter family 55 437 3.9E-23 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CFK41_RS15210 e5734a4b4332ab50c109071210d762e8 283 SUPERFAMILY SSF56601 20 266 3.65E-34 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CFK41_RS15210 e5734a4b4332ab50c109071210d762e8 283 Gene3D G3DSA:3.40.710.10 3 282 4.9E-33 T 28-03-2018 CFK41_RS15210 e5734a4b4332ab50c109071210d762e8 283 Pfam PF13354 Beta-lactamase enzyme family 23 248 1.9E-31 T 28-03-2018 CFK41_RS00740 587d1e4fc4cc1429cc7f9170d5c92326 327 SUPERFAMILY SSF103481 194 283 4.97E-12 T 28-03-2018 CFK41_RS00740 587d1e4fc4cc1429cc7f9170d5c92326 327 SUPERFAMILY SSF103481 48 144 9.55E-10 T 28-03-2018 CFK41_RS00740 587d1e4fc4cc1429cc7f9170d5c92326 327 Pfam PF00892 EamA-like transporter family 153 283 7.6E-22 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CFK41_RS00740 587d1e4fc4cc1429cc7f9170d5c92326 327 Pfam PF00892 EamA-like transporter family 10 142 5.7E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CFK41_RS00855 2c101643a208f4cdbd477b86a1bf07eb 713 Gene3D G3DSA:3.40.50.1820 419 702 1.7E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS00855 2c101643a208f4cdbd477b86a1bf07eb 713 Gene3D G3DSA:2.140.10.30 21 256 6.6E-8 T 28-03-2018 CFK41_RS00855 2c101643a208f4cdbd477b86a1bf07eb 713 Gene3D G3DSA:2.140.10.30 257 404 6.1E-6 T 28-03-2018 CFK41_RS00855 2c101643a208f4cdbd477b86a1bf07eb 713 Pfam PF00326 Prolyl oligopeptidase family 496 699 1.0E-45 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CFK41_RS00855 2c101643a208f4cdbd477b86a1bf07eb 713 SUPERFAMILY SSF53474 443 699 1.2E-55 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS00855 2c101643a208f4cdbd477b86a1bf07eb 713 SUPERFAMILY SSF69304 212 395 1.31E-8 T 28-03-2018 CFK41_RS07225 ce9374789e8da7072758049b5a023042 782 SMART SM01006 6 53 2.8E-11 T 28-03-2018 IPR019432 Siderophore biosynthesis protein, conserved domain CFK41_RS07225 ce9374789e8da7072758049b5a023042 782 Gene3D G3DSA:3.40.630.30 1 175 5.1E-13 T 28-03-2018 CFK41_RS07225 ce9374789e8da7072758049b5a023042 782 Pfam PF04183 IucA / IucC family 324 570 5.8E-73 T 28-03-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 CFK41_RS07225 ce9374789e8da7072758049b5a023042 782 Pfam PF06276 Ferric iron reductase FhuF-like transporter 591 744 1.3E-26 T 28-03-2018 IPR022770 Ferric iron reductase FhuF domain CFK41_RS07225 ce9374789e8da7072758049b5a023042 782 SUPERFAMILY SSF55729 1 170 1.21E-31 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS07225 ce9374789e8da7072758049b5a023042 782 Pfam PF13523 Acetyltransferase (GNAT) domain 9 152 9.5E-38 T 28-03-2018 CFK41_RS17145 04fe43954c3677fbc93cd098683428ea 468 Pfam PF02447 GntP family permease 5 464 1.2E-111 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CFK41_RS17145 04fe43954c3677fbc93cd098683428ea 468 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 6 467 1.2E-93 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CFK41_RS17145 04fe43954c3677fbc93cd098683428ea 468 PIRSF PIRSF002746 1 468 6.5E-124 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CFK41_RS06730 ba505a48343806e0d1cf58f36d3f7455 71 Gene3D G3DSA:3.30.70.100 1 71 2.5E-19 T 28-03-2018 CFK41_RS06730 ba505a48343806e0d1cf58f36d3f7455 71 PRINTS PR00946 Mercury scavenger protein signature 2 13 5.9E-7 T 28-03-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 CFK41_RS06730 ba505a48343806e0d1cf58f36d3f7455 71 PRINTS PR00946 Mercury scavenger protein signature 29 44 5.9E-7 T 28-03-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 CFK41_RS06730 ba505a48343806e0d1cf58f36d3f7455 71 PRINTS PR00946 Mercury scavenger protein signature 57 71 5.9E-7 T 28-03-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 CFK41_RS06730 ba505a48343806e0d1cf58f36d3f7455 71 PRINTS PR00946 Mercury scavenger protein signature 13 29 5.9E-7 T 28-03-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 CFK41_RS06730 ba505a48343806e0d1cf58f36d3f7455 71 Pfam PF00403 Heavy-metal-associated domain 8 66 1.7E-14 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CFK41_RS06730 ba505a48343806e0d1cf58f36d3f7455 71 SUPERFAMILY SSF55008 3 69 1.44E-17 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CFK41_RS04985 22459f2f41b32dedf1a74cd0db06d9d4 252 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 24 251 1.3E-62 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CFK41_RS04985 22459f2f41b32dedf1a74cd0db06d9d4 252 Gene3D G3DSA:3.40.1180.10 10 252 2.5E-80 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CFK41_RS04985 22459f2f41b32dedf1a74cd0db06d9d4 252 SUPERFAMILY SSF64005 24 246 1.7E-70 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CFK41_RS04985 22459f2f41b32dedf1a74cd0db06d9d4 252 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 197 214 - T 28-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 CFK41_RS04985 22459f2f41b32dedf1a74cd0db06d9d4 252 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 24 252 35.225 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CFK41_RS04985 22459f2f41b32dedf1a74cd0db06d9d4 252 Pfam PF01255 Putative undecaprenyl diphosphate synthase 31 251 5.6E-69 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CFK41_RS10360 9695ea513855abeb12bfdf5fe18f5cb5 208 SUPERFAMILY SSF55729 7 180 4.12E-36 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS10360 9695ea513855abeb12bfdf5fe18f5cb5 208 Pfam PF13302 Acetyltransferase (GNAT) domain 14 155 5.7E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS10360 9695ea513855abeb12bfdf5fe18f5cb5 208 Gene3D G3DSA:3.40.630.30 1 200 4.6E-28 T 28-03-2018 CFK41_RS16560 853dd568c3191211d4425e4e6804023c 435 SUPERFAMILY SSF103473 25 409 1.03E-48 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS16560 853dd568c3191211d4425e4e6804023c 435 Pfam PF07690 Major Facilitator Superfamily 37 374 5.3E-33 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS16560 853dd568c3191211d4425e4e6804023c 435 PRINTS PR01035 Tetracycline resistance protein signature 385 404 2.9E-16 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CFK41_RS16560 853dd568c3191211d4425e4e6804023c 435 PRINTS PR01035 Tetracycline resistance protein signature 157 179 2.9E-16 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CFK41_RS16560 853dd568c3191211d4425e4e6804023c 435 PRINTS PR01035 Tetracycline resistance protein signature 185 205 2.9E-16 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CFK41_RS16560 853dd568c3191211d4425e4e6804023c 435 PRINTS PR01035 Tetracycline resistance protein signature 43 59 2.9E-16 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CFK41_RS16560 853dd568c3191211d4425e4e6804023c 435 Gene3D G3DSA:1.20.1250.20 24 215 2.8E-21 T 28-03-2018 CFK41_RS16560 853dd568c3191211d4425e4e6804023c 435 Gene3D G3DSA:1.20.1250.20 217 411 6.7E-17 T 28-03-2018 CFK41_RS16365 f45ad48f2cdbb038c6db48703d342b5d 436 Gene3D G3DSA:1.20.144.10 100 318 3.0E-23 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CFK41_RS16365 f45ad48f2cdbb038c6db48703d342b5d 436 ProSitePatterns PS01157 Class A bacterial acid phosphatases signature. 231 238 - T 28-03-2018 IPR018296 Acid phosphatase, class A, bacterial, conserved site GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 CFK41_RS16365 f45ad48f2cdbb038c6db48703d342b5d 436 Pfam PF01569 PAP2 superfamily 196 291 2.4E-9 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CFK41_RS16365 f45ad48f2cdbb038c6db48703d342b5d 436 SUPERFAMILY SSF48317 170 312 4.19E-23 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CFK41_RS14455 f22034a1b9c44eed093f2596727f2137 410 Gene3D G3DSA:3.40.50.10840 1 233 6.1E-63 T 28-03-2018 IPR010737 Putative sugar-binding, N-terminal domain CFK41_RS14455 f22034a1b9c44eed093f2596727f2137 410 SUPERFAMILY SSF142764 2 409 1.14E-98 T 28-03-2018 CFK41_RS14455 f22034a1b9c44eed093f2596727f2137 410 Pfam PF07005 Putative sugar-binding N-terminal domain 2 224 2.0E-61 T 28-03-2018 IPR010737 Putative sugar-binding, N-terminal domain CFK41_RS14455 f22034a1b9c44eed093f2596727f2137 410 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 245 402 6.9E-31 T 28-03-2018 IPR031475 Putative nucleotide-binding C-terminal domain CFK41_RS14995 9ab5c6103314334a380d9228a2a1d8d1 292 Gene3D G3DSA:2.140.10.30 4 126 1.4E-14 T 28-03-2018 CFK41_RS14995 9ab5c6103314334a380d9228a2a1d8d1 292 Gene3D G3DSA:2.130.10.150 127 292 7.5E-21 T 28-03-2018 CFK41_RS14995 9ab5c6103314334a380d9228a2a1d8d1 292 Pfam PF07676 WD40-like Beta Propeller Repeat 161 198 1.6E-5 T 28-03-2018 IPR011659 WD40-like Beta Propeller CFK41_RS14995 9ab5c6103314334a380d9228a2a1d8d1 292 SUPERFAMILY SSF69304 39 285 7.85E-26 T 28-03-2018 CFK41_RS03045 999c647e85a7a05e990444c63fad7fa6 382 Gene3D G3DSA:3.90.25.10 205 377 7.9E-20 T 28-03-2018 CFK41_RS03045 999c647e85a7a05e990444c63fad7fa6 382 Gene3D G3DSA:3.40.50.720 1 204 1.7E-16 T 28-03-2018 CFK41_RS03045 999c647e85a7a05e990444c63fad7fa6 382 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 291 2.4E-23 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CFK41_RS03045 999c647e85a7a05e990444c63fad7fa6 382 SUPERFAMILY SSF51735 1 371 5.81E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS02425 3b68c83ad416a840e60c3234e1d607ac 298 Pfam PF01061 ABC-2 type transporter 65 257 3.1E-10 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CFK41_RS05665 fd42d40c7d2b32fc40f4de3a11dd8a67 244 Gene3D G3DSA:3.20.20.70 6 242 3.5E-53 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS05665 fd42d40c7d2b32fc40f4de3a11dd8a67 244 TIGRFAM TIGR01919 hisA-trpF: bifunctional HisA/TrpF protein 6 241 1.7E-114 T 28-03-2018 IPR010188 Bifunctional HisA/TrpF GO:0000105|GO:0000162|GO:0003949|GO:0004640|GO:0005737 KEGG: 00340+5.3.1.16 CFK41_RS05665 fd42d40c7d2b32fc40f4de3a11dd8a67 244 Pfam PF00977 Histidine biosynthesis protein 8 233 2.2E-62 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 CFK41_RS05665 fd42d40c7d2b32fc40f4de3a11dd8a67 244 SUPERFAMILY SSF51366 7 239 7.14E-62 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CFK41_RS05665 fd42d40c7d2b32fc40f4de3a11dd8a67 244 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 7 240 31.987 T 28-03-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 CFK41_RS02485 ff80c3117ee365ac53e8d9927d29b6b4 601 Pfam PF07940 Heparinase II/III-like protein 315 529 3.2E-19 T 28-03-2018 IPR012480 Heparinase II/III-like GO:0016829 CFK41_RS02485 ff80c3117ee365ac53e8d9927d29b6b4 601 Gene3D G3DSA:1.50.10.100 38 339 8.5E-21 T 28-03-2018 CFK41_RS02485 ff80c3117ee365ac53e8d9927d29b6b4 601 Pfam PF16889 Heparinase II/III N-terminus 58 283 3.1E-14 T 28-03-2018 IPR031680 Heparin-sulfate lyase, N-terminal MetaCyc: PWY-7651 CFK41_RS02485 ff80c3117ee365ac53e8d9927d29b6b4 601 SUPERFAMILY SSF48230 96 283 3.02E-14 T 28-03-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 CFK41_RS02675 58db45a51e5673435a89e07cb55163ae 274 Pfam PF01261 Xylose isomerase-like TIM barrel 43 214 7.0E-17 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS02675 58db45a51e5673435a89e07cb55163ae 274 SUPERFAMILY SSF51658 18 260 4.97E-33 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS02675 58db45a51e5673435a89e07cb55163ae 274 Gene3D G3DSA:3.20.20.150 5 269 1.0E-34 T 28-03-2018 CFK41_RS13245 195aa0fcc3b709c91789a8e143ac895b 338 Pfam PF01384 Phosphate transporter family 20 324 3.9E-53 T 28-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 CFK41_RS10700 5c1535be99a17b7b6f1cddcf2dae2e8c 121 SUPERFAMILY SSF56399 5 110 1.7E-15 T 28-03-2018 CFK41_RS10700 5c1535be99a17b7b6f1cddcf2dae2e8c 121 Pfam PF06108 Protein of unknown function (DUF952) 9 106 3.6E-21 T 28-03-2018 IPR009297 Protein of unknown function DUF952 CFK41_RS00695 7fda70c1f0bcb267449bba010f4d5735 333 Pfam PF03741 Integral membrane protein TerC family 70 271 4.5E-54 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CFK41_RS00695 7fda70c1f0bcb267449bba010f4d5735 333 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 10 317 9.0E-106 T 28-03-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 CFK41_RS02040 6305445544b1fddaaaad1f3dfbd0fdc7 675 SMART SM00382 428 614 2.6E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS02040 6305445544b1fddaaaad1f3dfbd0fdc7 675 SUPERFAMILY SSF90123 51 370 5.49E-83 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS02040 6305445544b1fddaaaad1f3dfbd0fdc7 675 Gene3D G3DSA:3.40.50.300 387 643 5.4E-72 T 28-03-2018 CFK41_RS02040 6305445544b1fddaaaad1f3dfbd0fdc7 675 Pfam PF00005 ABC transporter 420 568 1.3E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS02040 6305445544b1fddaaaad1f3dfbd0fdc7 675 Gene3D G3DSA:1.20.1560.10 30 373 1.3E-83 T 28-03-2018 CFK41_RS02040 6305445544b1fddaaaad1f3dfbd0fdc7 675 ProSitePatterns PS00211 ABC transporters family signature. 540 554 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS02040 6305445544b1fddaaaad1f3dfbd0fdc7 675 Pfam PF00664 ABC transporter transmembrane region 64 338 1.5E-57 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS02040 6305445544b1fddaaaad1f3dfbd0fdc7 675 SUPERFAMILY SSF52540 398 639 1.22E-87 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS17415 5954d989ada898389226b495e0fa64a8 146 Gene3D G3DSA:3.40.630.30 12 142 3.7E-21 T 28-03-2018 CFK41_RS17415 5954d989ada898389226b495e0fa64a8 146 Pfam PF00583 Acetyltransferase (GNAT) family 59 131 1.6E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS17415 5954d989ada898389226b495e0fa64a8 146 SUPERFAMILY SSF55729 21 135 5.48E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS12630 ad787162ed304c6045e37c1ad47f85af 284 Pfam PF00149 Calcineurin-like phosphoesterase 1 198 1.1E-16 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CFK41_RS12630 ad787162ed304c6045e37c1ad47f85af 284 Gene3D G3DSA:3.60.21.10 1 258 1.8E-43 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CFK41_RS12630 ad787162ed304c6045e37c1ad47f85af 284 SUPERFAMILY SSF56300 1 245 1.41E-46 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CFK41_RS00645 86133d372ba1d94318c02b42953deec1 123 Gene3D G3DSA:3.40.630.30 1 119 4.0E-19 T 28-03-2018 CFK41_RS00645 86133d372ba1d94318c02b42953deec1 123 SUPERFAMILY SSF55729 2 111 2.4E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS00645 86133d372ba1d94318c02b42953deec1 123 Pfam PF13673 Acetyltransferase (GNAT) domain 18 109 1.8E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS07590 8677f5b2756119e24dadae86caaaf86b 157 Gene3D G3DSA:1.10.10.10 10 150 5.7E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS07590 8677f5b2756119e24dadae86caaaf86b 157 SUPERFAMILY SSF46785 16 147 1.12E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS07590 8677f5b2756119e24dadae86caaaf86b 157 SMART SM00347 34 134 8.1E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CFK41_RS07590 8677f5b2756119e24dadae86caaaf86b 157 Pfam PF12802 MarR family 39 98 7.4E-13 T 28-03-2018 CFK41_RS07200 c647bfe5d91a4b666d1404c1b2e5c49d 98 SUPERFAMILY SSF141000 3 94 8.89E-27 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CFK41_RS07200 c647bfe5d91a4b666d1404c1b2e5c49d 98 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 5 95 4.0E-25 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CFK41_RS07200 c647bfe5d91a4b666d1404c1b2e5c49d 98 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 1 96 23.255 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CFK41_RS07200 c647bfe5d91a4b666d1404c1b2e5c49d 98 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 91 5.6E-17 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CFK41_RS03170 69c9cc50d89125f2b70a24028c0f4a56 346 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 6 340 1.5E-101 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CFK41_RS03170 69c9cc50d89125f2b70a24028c0f4a56 346 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 19 28 - T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CFK41_RS03170 69c9cc50d89125f2b70a24028c0f4a56 346 Gene3D G3DSA:3.20.20.210 3 342 6.2E-87 T 28-03-2018 CFK41_RS03170 69c9cc50d89125f2b70a24028c0f4a56 346 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 3 342 40.306 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CFK41_RS03170 69c9cc50d89125f2b70a24028c0f4a56 346 SUPERFAMILY SSF51726 8 341 4.19E-87 T 28-03-2018 CFK41_RS03170 69c9cc50d89125f2b70a24028c0f4a56 346 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 139 155 - T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CFK41_RS03170 69c9cc50d89125f2b70a24028c0f4a56 346 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 6 340 8.1E-107 T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CFK41_RS02850 f56db91b98b7bcfe40edba75d922ab4a 707 SUPERFAMILY SSF90123 28 346 1.44E-57 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS02850 f56db91b98b7bcfe40edba75d922ab4a 707 Gene3D G3DSA:1.20.1560.10 23 352 2.5E-50 T 28-03-2018 CFK41_RS02850 f56db91b98b7bcfe40edba75d922ab4a 707 SMART SM00382 408 593 2.1E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS02850 f56db91b98b7bcfe40edba75d922ab4a 707 SUPERFAMILY SSF52540 392 615 7.07E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS02850 f56db91b98b7bcfe40edba75d922ab4a 707 Pfam PF00005 ABC transporter 410 547 2.8E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS02850 f56db91b98b7bcfe40edba75d922ab4a 707 Gene3D G3DSA:3.40.50.300 353 623 3.9E-58 T 28-03-2018 CFK41_RS02850 f56db91b98b7bcfe40edba75d922ab4a 707 ProSitePatterns PS00211 ABC transporters family signature. 519 533 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS02850 f56db91b98b7bcfe40edba75d922ab4a 707 Pfam PF00664 ABC transporter transmembrane region 44 315 8.8E-29 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CFK41_RS03085 abe861b87bfe0b893ca72f4564f1fb8e 412 Gene3D G3DSA:3.20.20.30 10 369 3.7E-69 T 28-03-2018 CFK41_RS03085 abe861b87bfe0b893ca72f4564f1fb8e 412 TIGRFAM TIGR04021 LLM_DMSO2_sfnG: dimethyl sulfone monooxygenase SfnG 14 366 1.4E-177 T 28-03-2018 IPR024014 Dimethyl sulphone monooxygenase SfnG CFK41_RS03085 abe861b87bfe0b893ca72f4564f1fb8e 412 Pfam PF00296 Luciferase-like monooxygenase 15 337 5.1E-67 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CFK41_RS03085 abe861b87bfe0b893ca72f4564f1fb8e 412 SUPERFAMILY SSF51679 12 376 1.24E-79 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CFK41_RS02015 f884cdeaabeaf8ff03f732084d829095 398 Pfam PF07690 Major Facilitator Superfamily 10 342 2.4E-18 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS02015 f884cdeaabeaf8ff03f732084d829095 398 Gene3D G3DSA:1.20.1250.20 196 391 4.7E-12 T 28-03-2018 CFK41_RS02015 f884cdeaabeaf8ff03f732084d829095 398 Gene3D G3DSA:1.20.1250.20 3 188 9.8E-15 T 28-03-2018 CFK41_RS02015 f884cdeaabeaf8ff03f732084d829095 398 SUPERFAMILY SSF103473 8 380 7.19E-31 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS13615 6e6124bbddedb559389fd208fa638fb5 161 Gene3D G3DSA:2.30.110.10 1 161 1.1E-21 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CFK41_RS13615 6e6124bbddedb559389fd208fa638fb5 161 SUPERFAMILY SSF50475 7 157 2.11E-24 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CFK41_RS13615 6e6124bbddedb559389fd208fa638fb5 161 Pfam PF01613 Flavin reductase like domain 15 156 7.9E-19 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CFK41_RS13615 6e6124bbddedb559389fd208fa638fb5 161 SMART SM00903 12 159 3.1E-13 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CFK41_RS11060 b6c3e9490cfef310305886f01baffa48 139 Pfam PF13857 Ankyrin repeats (many copies) 38 89 5.9E-14 T 28-03-2018 CFK41_RS11060 b6c3e9490cfef310305886f01baffa48 139 PRINTS PR01415 Ankyrin repeat signature 52 67 1.6E-5 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CFK41_RS11060 b6c3e9490cfef310305886f01baffa48 139 PRINTS PR01415 Ankyrin repeat signature 100 114 1.6E-5 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CFK41_RS11060 b6c3e9490cfef310305886f01baffa48 139 Gene3D G3DSA:1.25.40.20 10 132 1.3E-27 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CFK41_RS11060 b6c3e9490cfef310305886f01baffa48 139 SUPERFAMILY SSF48403 23 113 1.55E-23 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CFK41_RS11060 b6c3e9490cfef310305886f01baffa48 139 SMART SM00248 84 113 1.1 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CFK41_RS11060 b6c3e9490cfef310305886f01baffa48 139 SMART SM00248 51 80 6.8E-6 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CFK41_RS12150 6df7dc87138db816a07b6a7dc2104f1f 210 Gene3D G3DSA:3.90.226.10 27 199 2.2E-42 T 28-03-2018 CFK41_RS12150 6df7dc87138db816a07b6a7dc2104f1f 210 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 9 199 40.107 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CFK41_RS12150 6df7dc87138db816a07b6a7dc2104f1f 210 PRINTS PR00127 Clp protease catalytic subunit P signature 65 85 1.5E-46 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CFK41_RS12150 6df7dc87138db816a07b6a7dc2104f1f 210 PRINTS PR00127 Clp protease catalytic subunit P signature 25 40 1.5E-46 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CFK41_RS12150 6df7dc87138db816a07b6a7dc2104f1f 210 PRINTS PR00127 Clp protease catalytic subunit P signature 96 113 1.5E-46 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CFK41_RS12150 6df7dc87138db816a07b6a7dc2104f1f 210 PRINTS PR00127 Clp protease catalytic subunit P signature 174 193 1.5E-46 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CFK41_RS12150 6df7dc87138db816a07b6a7dc2104f1f 210 PRINTS PR00127 Clp protease catalytic subunit P signature 117 136 1.5E-46 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CFK41_RS12150 6df7dc87138db816a07b6a7dc2104f1f 210 Pfam PF00574 Clp protease 25 197 7.7E-78 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CFK41_RS12150 6df7dc87138db816a07b6a7dc2104f1f 210 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 118 131 - T 28-03-2018 IPR033135 ClpP, histidine active site CFK41_RS12150 6df7dc87138db816a07b6a7dc2104f1f 210 SUPERFAMILY SSF52096 25 197 3.03E-65 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CFK41_RS11325 9ee28942d19b56f1ea94a4137c361cac 423 Pfam PF05977 Transmembrane secretion effector 36 389 8.2E-6 T 28-03-2018 IPR010290 Transmembrane secretion effector CFK41_RS11325 9ee28942d19b56f1ea94a4137c361cac 423 Gene3D G3DSA:1.20.1250.20 1 200 2.5E-9 T 28-03-2018 CFK41_RS11325 9ee28942d19b56f1ea94a4137c361cac 423 SUPERFAMILY SSF103473 5 395 6.93E-33 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS11325 9ee28942d19b56f1ea94a4137c361cac 423 Gene3D G3DSA:1.20.1250.20 202 410 3.3E-15 T 28-03-2018 CFK41_RS08270 be272b73b89dee39466ac2494b15f27f 244 Gene3D G3DSA:3.40.50.300 1 217 9.0E-53 T 28-03-2018 CFK41_RS08270 be272b73b89dee39466ac2494b15f27f 244 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS08270 be272b73b89dee39466ac2494b15f27f 244 SMART SM00382 23 213 9.7E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS08270 be272b73b89dee39466ac2494b15f27f 244 SUPERFAMILY SSF52540 1 212 2.9E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS08270 be272b73b89dee39466ac2494b15f27f 244 Pfam PF00005 ABC transporter 14 158 3.8E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS05305 a8992a4616850cfac22a7096cce3656a 258 Pfam PF11350 Protein of unknown function (DUF3152) 79 243 8.7E-33 T 28-03-2018 IPR022603 Domain of unknown function DUF3152 CFK41_RS05305 a8992a4616850cfac22a7096cce3656a 258 Gene3D G3DSA:3.40.390.10 101 243 7.2E-8 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CFK41_RS05305 a8992a4616850cfac22a7096cce3656a 258 SUPERFAMILY SSF55486 125 241 1.11E-15 T 28-03-2018 CFK41_RS00245 3f586119aeb910762315410e1352c0ae 462 PIRSF PIRSF006060 3 460 1.2E-58 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CFK41_RS00245 3f586119aeb910762315410e1352c0ae 462 ProSitePatterns PS00218 Amino acid permeases signature. 49 79 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CFK41_RS00245 3f586119aeb910762315410e1352c0ae 462 Pfam PF00324 Amino acid permease 24 430 1.2E-89 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CFK41_RS05870 ef441faeaf62e492f0121167e24b6f8e 668 Gene3D G3DSA:2.60.200.20 391 667 1.1E-11 T 28-03-2018 CFK41_RS05870 ef441faeaf62e492f0121167e24b6f8e 668 Pfam PF06271 RDD family 146 272 6.3E-15 T 28-03-2018 IPR010432 RDD CFK41_RS05870 ef441faeaf62e492f0121167e24b6f8e 668 SMART SM00240 579 636 0.0026 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CFK41_RS05870 ef441faeaf62e492f0121167e24b6f8e 668 SUPERFAMILY SSF49879 575 664 6.08E-12 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 CFK41_RS05870 ef441faeaf62e492f0121167e24b6f8e 668 Pfam PF00498 FHA domain 580 658 8.5E-7 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CFK41_RS11145 422a273b667a6fa7cb6211b02b40024c 149 Pfam PF01152 Bacterial-like globin 12 128 3.5E-35 T 28-03-2018 IPR001486 Truncated hemoglobin GO:0019825 CFK41_RS11145 422a273b667a6fa7cb6211b02b40024c 149 Gene3D G3DSA:1.10.490.10 1 137 1.2E-34 T 28-03-2018 CFK41_RS11145 422a273b667a6fa7cb6211b02b40024c 149 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 59 83 - T 28-03-2018 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 CFK41_RS11145 422a273b667a6fa7cb6211b02b40024c 149 SUPERFAMILY SSF46458 12 131 4.32E-35 T 28-03-2018 IPR009050 Globin-like CFK41_RS15650 da679c9e9546fa73b2730cdfd6a8cfc5 448 Gene3D G3DSA:1.10.510.10 88 336 2.3E-33 T 28-03-2018 CFK41_RS15650 da679c9e9546fa73b2730cdfd6a8cfc5 448 Gene3D G3DSA:3.30.200.20 4 87 1.7E-15 T 28-03-2018 CFK41_RS15650 da679c9e9546fa73b2730cdfd6a8cfc5 448 Pfam PF00069 Protein kinase domain 12 208 7.0E-35 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CFK41_RS15650 da679c9e9546fa73b2730cdfd6a8cfc5 448 SUPERFAMILY SSF56112 5 351 2.56E-54 T 28-03-2018 IPR011009 Protein kinase-like domain CFK41_RS15650 da679c9e9546fa73b2730cdfd6a8cfc5 448 SMART SM00220 9 257 3.4E-31 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CFK41_RS05880 40fc591192b41e51c0759927132c148f 1012 Pfam PF00498 FHA domain 920 1001 2.7E-6 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CFK41_RS05880 40fc591192b41e51c0759927132c148f 1012 SUPERFAMILY SSF49879 912 1006 5.16E-11 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 CFK41_RS05880 40fc591192b41e51c0759927132c148f 1012 Gene3D G3DSA:2.60.200.20 563 1009 5.3E-12 T 28-03-2018 CFK41_RS01700 f3da59648c2380ecc9733fbea83a3ae1 282 Gene3D G3DSA:3.20.20.150 3 281 6.5E-36 T 28-03-2018 CFK41_RS01700 f3da59648c2380ecc9733fbea83a3ae1 282 SUPERFAMILY SSF51658 7 270 3.04E-40 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS01700 f3da59648c2380ecc9733fbea83a3ae1 282 Pfam PF01261 Xylose isomerase-like TIM barrel 21 232 7.4E-15 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS08135 5cc07e5cede69cd7871be1a6df58bfd9 293 Pfam PF11296 Protein of unknown function (DUF3097) 8 289 2.6E-117 T 28-03-2018 IPR021447 Protein of unknown function DUF3097 CFK41_RS12275 95d7bff6f610a61d4486d8479cb7597e 229 Pfam PF00072 Response regulator receiver domain 4 113 7.5E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS12275 95d7bff6f610a61d4486d8479cb7597e 229 SMART SM00862 149 225 1.6E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CFK41_RS12275 95d7bff6f610a61d4486d8479cb7597e 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 225 6.9E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CFK41_RS12275 95d7bff6f610a61d4486d8479cb7597e 229 Gene3D G3DSA:3.40.50.2300 1 123 3.7E-39 T 28-03-2018 CFK41_RS12275 95d7bff6f610a61d4486d8479cb7597e 229 SUPERFAMILY SSF52172 1 121 2.28E-42 T 28-03-2018 IPR011006 CheY-like superfamily CFK41_RS12275 95d7bff6f610a61d4486d8479cb7597e 229 SUPERFAMILY SSF46894 125 226 2.78E-31 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CFK41_RS12275 95d7bff6f610a61d4486d8479cb7597e 229 SMART SM00448 2 112 1.3E-46 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS12275 95d7bff6f610a61d4486d8479cb7597e 229 Gene3D G3DSA:1.10.10.10 124 229 1.3E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS12705 4e1cba2adfb0ba27487b94fb2ab09e2d 427 SUPERFAMILY SSF53335 81 241 4.44E-17 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS12705 4e1cba2adfb0ba27487b94fb2ab09e2d 427 Gene3D G3DSA:3.40.50.150 92 269 2.7E-12 T 28-03-2018 CFK41_RS12705 4e1cba2adfb0ba27487b94fb2ab09e2d 427 Gene3D G3DSA:3.40.50.150 1 91 0.031 T 28-03-2018 CFK41_RS11775 ed78dd3fdf3418ad57e244aebda4d540 472 SUPERFAMILY SSF48208 145 470 5.83E-30 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CFK41_RS11775 ed78dd3fdf3418ad57e244aebda4d540 472 Gene3D G3DSA:1.50.10.10 146 472 5.8E-30 T 28-03-2018 CFK41_RS00600 5b686546ae063d41657a560926744d16 71 SUPERFAMILY SSF47413 3 65 1.21E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS00600 5b686546ae063d41657a560926744d16 71 SMART SM00530 4 59 1.0E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CFK41_RS00600 5b686546ae063d41657a560926744d16 71 Pfam PF01381 Helix-turn-helix 5 59 5.8E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CFK41_RS00600 5b686546ae063d41657a560926744d16 71 Gene3D G3DSA:1.10.260.40 1 66 7.9E-18 T 28-03-2018 CFK41_RS06290 0c56ad37758048a297e809752131f04d 283 Pfam PF06271 RDD family 31 161 6.9E-16 T 28-03-2018 IPR010432 RDD CFK41_RS11960 f48dbe087128de8b23af54402fbf7245 415 Gene3D G3DSA:2.60.120.580 220 317 3.5E-27 T 28-03-2018 CFK41_RS11960 f48dbe087128de8b23af54402fbf7245 415 Gene3D G3DSA:2.60.120.580 30 218 1.1E-27 T 28-03-2018 CFK41_RS11960 f48dbe087128de8b23af54402fbf7245 415 SUPERFAMILY SSF141130 199 415 3.4E-71 T 28-03-2018 CFK41_RS11960 f48dbe087128de8b23af54402fbf7245 415 SUPERFAMILY SSF141130 118 169 3.4E-71 T 28-03-2018 CFK41_RS11960 f48dbe087128de8b23af54402fbf7245 415 SUPERFAMILY SSF141130 42 82 3.4E-71 T 28-03-2018 CFK41_RS11960 f48dbe087128de8b23af54402fbf7245 415 Pfam PF03069 Acetamidase/Formamidase family 248 402 5.2E-21 T 28-03-2018 IPR004304 Acetamidase/Formamidase GO:0016811 CFK41_RS11960 f48dbe087128de8b23af54402fbf7245 415 Pfam PF03069 Acetamidase/Formamidase family 116 240 2.6E-8 T 28-03-2018 IPR004304 Acetamidase/Formamidase GO:0016811 CFK41_RS11960 f48dbe087128de8b23af54402fbf7245 415 Gene3D G3DSA:3.10.28.20 328 415 1.2E-28 T 28-03-2018 CFK41_RS00405 c39242b886169a1facd4eaf807752be1 237 Gene3D G3DSA:3.40.50.7700 95 235 5.6E-29 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CFK41_RS00405 c39242b886169a1facd4eaf807752be1 237 SUPERFAMILY SSF52255 102 231 8.5E-23 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CFK41_RS00405 c39242b886169a1facd4eaf807752be1 237 SMART SM01001 102 234 2.0E-15 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CFK41_RS00405 c39242b886169a1facd4eaf807752be1 237 Pfam PF00731 AIR carboxylase 104 229 1.3E-10 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CFK41_RS06210 5d9984251357304b3d334822ae2338af 235 Pfam PF00535 Glycosyl transferase family 2 20 142 3.2E-17 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CFK41_RS06210 5d9984251357304b3d334822ae2338af 235 Gene3D G3DSA:3.90.550.10 2 231 5.4E-17 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS06210 5d9984251357304b3d334822ae2338af 235 SUPERFAMILY SSF53448 20 221 3.56E-24 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS04025 7ebf911bb71d479ea538210c1c51c397 217 Gene3D G3DSA:3.30.70.240 137 203 4.5E-9 T 28-03-2018 CFK41_RS04025 7ebf911bb71d479ea538210c1c51c397 217 Gene3D G3DSA:3.30.230.30 4 135 2.9E-38 T 28-03-2018 IPR001498 Impact, N-terminal CFK41_RS04025 7ebf911bb71d479ea538210c1c51c397 217 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 81 110 - T 28-03-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site CFK41_RS04025 7ebf911bb71d479ea538210c1c51c397 217 Pfam PF01205 Uncharacterized protein family UPF0029 18 125 3.9E-26 T 28-03-2018 IPR001498 Impact, N-terminal CFK41_RS04025 7ebf911bb71d479ea538210c1c51c397 217 SUPERFAMILY SSF54211 8 132 6.83E-36 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CFK41_RS05250 f83d4cbf28b891d23820c4ee2a86ac9d 110 SUPERFAMILY SSF54909 30 106 1.17E-13 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CFK41_RS05250 f83d4cbf28b891d23820c4ee2a86ac9d 110 Gene3D G3DSA:3.30.70.100 18 107 3.9E-9 T 28-03-2018 CFK41_RS05250 f83d4cbf28b891d23820c4ee2a86ac9d 110 Pfam PF03992 Antibiotic biosynthesis monooxygenase 30 85 6.9E-8 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CFK41_RS07430 27be0f07f5d5ce8bbe76e51328345817 171 Gene3D G3DSA:3.40.630.30 8 166 6.1E-24 T 28-03-2018 CFK41_RS07430 27be0f07f5d5ce8bbe76e51328345817 171 SUPERFAMILY SSF55729 10 155 6.91E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS07430 27be0f07f5d5ce8bbe76e51328345817 171 Pfam PF00583 Acetyltransferase (GNAT) family 77 149 9.4E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS16650 4e07ce9594a6fa0404646f6ae6eb663b 341 Gene3D G3DSA:3.20.20.100 3 334 3.8E-56 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS16650 4e07ce9594a6fa0404646f6ae6eb663b 341 SUPERFAMILY SSF51430 3 319 3.01E-59 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS16650 4e07ce9594a6fa0404646f6ae6eb663b 341 Pfam PF00248 Aldo/keto reductase family 18 313 1.3E-45 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS09050 9c583313927db079f877302a6efc4bb6 135 Gene3D G3DSA:3.10.180.10 1 132 3.2E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS09050 9c583313927db079f877302a6efc4bb6 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 117 8.1E-6 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CFK41_RS09050 9c583313927db079f877302a6efc4bb6 135 SUPERFAMILY SSF54593 6 121 1.38E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS16565 302656a731c6cd85b6a06df09b50cd92 582 Pfam PF01019 Gamma-glutamyltranspeptidase 14 575 6.5E-120 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CFK41_RS16565 302656a731c6cd85b6a06df09b50cd92 582 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 111 130 7.6E-25 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CFK41_RS16565 302656a731c6cd85b6a06df09b50cd92 582 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 93 111 7.6E-25 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CFK41_RS16565 302656a731c6cd85b6a06df09b50cd92 582 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 469 486 7.6E-25 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CFK41_RS16565 302656a731c6cd85b6a06df09b50cd92 582 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 22 47 7.6E-25 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CFK41_RS16565 302656a731c6cd85b6a06df09b50cd92 582 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 445 460 7.6E-25 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CFK41_RS16565 302656a731c6cd85b6a06df09b50cd92 582 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 391 409 7.6E-25 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CFK41_RS16565 302656a731c6cd85b6a06df09b50cd92 582 SUPERFAMILY SSF56235 1 345 8.88E-120 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CFK41_RS16565 302656a731c6cd85b6a06df09b50cd92 582 SUPERFAMILY SSF56235 386 581 8.88E-120 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CFK41_RS06645 641702b35b1e236b7f49a230496c17de 230 SUPERFAMILY SSF53254 1 178 2.08E-48 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CFK41_RS06645 641702b35b1e236b7f49a230496c17de 230 PIRSF PIRSF000709 4 113 6.3E-6 T 28-03-2018 CFK41_RS06645 641702b35b1e236b7f49a230496c17de 230 PIRSF PIRSF000709 126 213 8.6 T 28-03-2018 CFK41_RS06645 641702b35b1e236b7f49a230496c17de 230 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CFK41_RS06645 641702b35b1e236b7f49a230496c17de 230 Gene3D G3DSA:3.40.50.1240 1 197 8.1E-44 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CFK41_RS06645 641702b35b1e236b7f49a230496c17de 230 SMART SM00855 3 147 1.8E-20 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CFK41_RS06645 641702b35b1e236b7f49a230496c17de 230 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 178 3.5E-46 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CFK41_RS03750 5d7dc11591eb22f87d9aebfe29b7c8fa 572 Gene3D G3DSA:3.40.50.300 399 563 1.1E-34 T 28-03-2018 CFK41_RS03750 5d7dc11591eb22f87d9aebfe29b7c8fa 572 Pfam PF00005 ABC transporter 42 219 2.7E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS03750 5d7dc11591eb22f87d9aebfe29b7c8fa 572 Pfam PF00005 ABC transporter 402 529 4.1E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS03750 5d7dc11591eb22f87d9aebfe29b7c8fa 572 SUPERFAMILY SSF52540 28 253 2.94E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS03750 5d7dc11591eb22f87d9aebfe29b7c8fa 572 SUPERFAMILY SSF52540 401 560 1.57E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS03750 5d7dc11591eb22f87d9aebfe29b7c8fa 572 SMART SM00382 51 264 2.5E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS03750 5d7dc11591eb22f87d9aebfe29b7c8fa 572 SMART SM00382 409 569 1.3E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS03750 5d7dc11591eb22f87d9aebfe29b7c8fa 572 Gene3D G3DSA:3.40.50.300 25 321 3.5E-41 T 28-03-2018 CFK41_RS11150 d62e09bf466da05da36b92ad8ad059e3 173 Gene3D G3DSA:3.10.129.10 14 169 1.6E-27 T 28-03-2018 CFK41_RS11150 d62e09bf466da05da36b92ad8ad059e3 173 Pfam PF13279 Thioesterase-like superfamily 23 151 4.8E-12 T 28-03-2018 CFK41_RS11150 d62e09bf466da05da36b92ad8ad059e3 173 SUPERFAMILY SSF54637 20 166 2.2E-23 T 28-03-2018 IPR029069 HotDog domain CFK41_RS09740 ab43697e2d049001bd7cd4085cf41f85 299 SUPERFAMILY SSF56300 66 296 2.1E-35 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CFK41_RS09740 ab43697e2d049001bd7cd4085cf41f85 299 Pfam PF00149 Calcineurin-like phosphoesterase 66 234 8.4E-10 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CFK41_RS09740 ab43697e2d049001bd7cd4085cf41f85 299 Gene3D G3DSA:3.60.21.10 65 296 4.0E-24 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CFK41_RS03435 9e80103c5280edb387a9ce5e02eca215 243 Pfam PF02223 Thymidylate kinase 26 216 6.3E-43 T 28-03-2018 CFK41_RS03435 9e80103c5280edb387a9ce5e02eca215 243 SUPERFAMILY SSF52540 19 225 8.74E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS03435 9e80103c5280edb387a9ce5e02eca215 243 Gene3D G3DSA:3.40.50.300 19 224 9.8E-48 T 28-03-2018 CFK41_RS03435 9e80103c5280edb387a9ce5e02eca215 243 ProSitePatterns PS01331 Thymidylate kinase signature. 113 125 - T 28-03-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CFK41_RS03435 9e80103c5280edb387a9ce5e02eca215 243 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 20 216 9.5E-45 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CFK41_RS03435 9e80103c5280edb387a9ce5e02eca215 243 Hamap MF_00165 Thymidylate kinase [tmk]. 22 224 29.088 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CFK41_RS13850 7463d32b4442fb66b75d0dfdf5a1eab2 900 Gene3D G3DSA:3.90.320.10 509 784 1.2E-5 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CFK41_RS13850 7463d32b4442fb66b75d0dfdf5a1eab2 900 Pfam PF12705 PD-(D/E)XK nuclease superfamily 592 893 4.4E-17 T 28-03-2018 CFK41_RS00025 2f23723cd22b4ba6c28a722324f3938e 198 SUPERFAMILY SSF53474 5 193 2.2E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS00025 2f23723cd22b4ba6c28a722324f3938e 198 Pfam PF02230 Phospholipase/Carboxylesterase 7 192 2.1E-14 T 28-03-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 CFK41_RS00025 2f23723cd22b4ba6c28a722324f3938e 198 Gene3D G3DSA:3.40.50.1820 2 198 1.5E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS04045 642efbc8c0d7a096ac7253a7a7d9999b 179 Pfam PF00583 Acetyltransferase (GNAT) family 66 138 7.1E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS04045 642efbc8c0d7a096ac7253a7a7d9999b 179 SUPERFAMILY SSF55729 15 140 1.52E-15 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS04045 642efbc8c0d7a096ac7253a7a7d9999b 179 TIGRFAM TIGR02406 ectoine_EctA: diaminobutyrate acetyltransferase 23 173 4.1E-50 T 28-03-2018 IPR012772 L-2,4-diaminobutyric acid acetyltransferase GO:0019491|GO:0033816 KEGG: 00250+2.3.1.17|KEGG: 00260+2.3.1.178 CFK41_RS04045 642efbc8c0d7a096ac7253a7a7d9999b 179 Gene3D G3DSA:3.40.630.30 20 179 7.2E-22 T 28-03-2018 CFK41_RS17495 db4a26a07edfc53eb7ec46638085335d 367 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 33 255 1.3E-56 T 28-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CFK41_RS17495 db4a26a07edfc53eb7ec46638085335d 367 Pfam PF02096 60Kd inner membrane protein 34 255 1.2E-51 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CFK41_RS09255 991c37a88ac3d8b473d492b85332a898 225 SUPERFAMILY SSF56281 24 221 5.63E-47 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS09255 991c37a88ac3d8b473d492b85332a898 225 Pfam PF00753 Metallo-beta-lactamase superfamily 32 200 6.9E-16 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS09255 991c37a88ac3d8b473d492b85332a898 225 Gene3D G3DSA:3.60.15.10 17 223 6.9E-36 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS09255 991c37a88ac3d8b473d492b85332a898 225 SMART SM00849 35 204 3.1E-29 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS04690 a29650f78f1ef09c1ba9c361323d9264 199 ProSitePatterns PS00113 Adenylate kinase signature. 92 103 - T 28-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CFK41_RS04690 a29650f78f1ef09c1ba9c361323d9264 199 Gene3D G3DSA:3.40.50.300 13 141 9.0E-35 T 28-03-2018 CFK41_RS04690 a29650f78f1ef09c1ba9c361323d9264 199 Gene3D G3DSA:3.40.50.300 142 198 1.8E-11 T 28-03-2018 CFK41_RS04690 a29650f78f1ef09c1ba9c361323d9264 199 PRINTS PR00094 Adenylate kinase signature 43 57 4.7E-35 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CFK41_RS04690 a29650f78f1ef09c1ba9c361323d9264 199 PRINTS PR00094 Adenylate kinase signature 15 28 4.7E-35 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CFK41_RS04690 a29650f78f1ef09c1ba9c361323d9264 199 PRINTS PR00094 Adenylate kinase signature 144 159 4.7E-35 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CFK41_RS04690 a29650f78f1ef09c1ba9c361323d9264 199 PRINTS PR00094 Adenylate kinase signature 161 175 4.7E-35 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CFK41_RS04690 a29650f78f1ef09c1ba9c361323d9264 199 PRINTS PR00094 Adenylate kinase signature 92 108 4.7E-35 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CFK41_RS04690 a29650f78f1ef09c1ba9c361323d9264 199 Pfam PF00406 Adenylate kinase 16 174 1.2E-51 T 28-03-2018 CFK41_RS04690 a29650f78f1ef09c1ba9c361323d9264 199 SUPERFAMILY SSF52540 12 197 3.58E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS04690 a29650f78f1ef09c1ba9c361323d9264 199 Hamap MF_00235 Adenylate kinase [adk]. 12 197 43.537 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CFK41_RS08010 f16e649b5f03d607bdc21e21f3abf25d 368 Pfam PF01757 Acyltransferase family 31 334 3.8E-18 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CFK41_RS16355 8b79d0b89d032a5fa8f4f71c1e72a9a3 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 251 1.8E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS16355 8b79d0b89d032a5fa8f4f71c1e72a9a3 266 SUPERFAMILY SSF161098 4 265 1.13E-64 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS16355 8b79d0b89d032a5fa8f4f71c1e72a9a3 266 Gene3D G3DSA:1.10.3720.10 2 253 5.0E-40 T 28-03-2018 CFK41_RS03035 67ddcb8c686758fa10dc59bc766f92f0 276 Pfam PF00144 Beta-lactamase 44 254 5.2E-23 T 28-03-2018 IPR001466 Beta-lactamase-related CFK41_RS03035 67ddcb8c686758fa10dc59bc766f92f0 276 SUPERFAMILY SSF56601 38 271 3.05E-42 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CFK41_RS03035 67ddcb8c686758fa10dc59bc766f92f0 276 Gene3D G3DSA:3.40.710.10 13 276 9.8E-40 T 28-03-2018 CFK41_RS01280 6f855c4ba0f24ef0b2304b946f59b2f6 437 Gene3D G3DSA:3.40.190.10 46 228 1.7E-29 T 28-03-2018 CFK41_RS01280 6f855c4ba0f24ef0b2304b946f59b2f6 437 SUPERFAMILY SSF53850 43 431 1.71E-47 T 28-03-2018 CFK41_RS01280 6f855c4ba0f24ef0b2304b946f59b2f6 437 Pfam PF13416 Bacterial extracellular solute-binding protein 68 363 2.1E-25 T 28-03-2018 CFK41_RS01280 6f855c4ba0f24ef0b2304b946f59b2f6 437 Gene3D G3DSA:3.40.190.10 229 382 0.037 T 28-03-2018 CFK41_RS14130 4c809eb5aa5b2c06a9911a4c83e6dbc2 284 SUPERFAMILY SSF140453 8 92 1.14E-5 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CFK41_RS14130 4c809eb5aa5b2c06a9911a4c83e6dbc2 284 Gene3D G3DSA:1.10.287.1060 3 98 8.2E-9 T 28-03-2018 CFK41_RS11405 12802cb0c307907886de4ba0194acfb0 519 Pfam PF15975 Flotillin 375 461 4.6E-12 T 28-03-2018 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 CFK41_RS11405 12802cb0c307907886de4ba0194acfb0 519 SUPERFAMILY SSF117892 72 210 2.48E-23 T 28-03-2018 IPR001107 Band 7 domain CFK41_RS11405 12802cb0c307907886de4ba0194acfb0 519 Pfam PF01145 SPFH domain / Band 7 family 33 219 7.3E-14 T 28-03-2018 IPR001107 Band 7 domain CFK41_RS05055 73a99c549f94d577d30542345b58e79f 216 Gene3D G3DSA:3.40.50.720 1 216 1.7E-21 T 28-03-2018 CFK41_RS05055 73a99c549f94d577d30542345b58e79f 216 SUPERFAMILY SSF51735 1 214 1.97E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS05055 73a99c549f94d577d30542345b58e79f 216 Pfam PF13460 NAD(P)H-binding 8 205 8.0E-21 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS06580 64c533e61a7bf816c5162d13979ca9ef 374 SUPERFAMILY SSF56601 45 365 2.23E-62 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CFK41_RS06580 64c533e61a7bf816c5162d13979ca9ef 374 Gene3D G3DSA:3.40.710.10 3 373 3.9E-64 T 28-03-2018 CFK41_RS06580 64c533e61a7bf816c5162d13979ca9ef 374 Pfam PF00144 Beta-lactamase 55 367 7.0E-55 T 28-03-2018 IPR001466 Beta-lactamase-related CFK41_RS08065 7f9557b558dd26d783ac321b5d3af5ee 786 Pfam PF03772 Competence protein 227 495 6.4E-47 T 28-03-2018 IPR004477 ComEC/Rec2-related protein CFK41_RS08065 7f9557b558dd26d783ac321b5d3af5ee 786 SMART SM00849 538 744 5.9E-7 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS08065 7f9557b558dd26d783ac321b5d3af5ee 786 Pfam PF00753 Metallo-beta-lactamase superfamily 537 599 6.5E-10 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS08065 7f9557b558dd26d783ac321b5d3af5ee 786 SUPERFAMILY SSF56281 527 772 1.27E-31 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS08065 7f9557b558dd26d783ac321b5d3af5ee 786 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 248 420 3.1E-23 T 28-03-2018 IPR004477 ComEC/Rec2-related protein CFK41_RS08065 7f9557b558dd26d783ac321b5d3af5ee 786 Gene3D G3DSA:3.60.15.10 522 762 2.1E-24 T 28-03-2018 IPR001279 Metallo-beta-lactamase CFK41_RS12945 8093dd22d2bdb82f679c13c6f503dcbe 184 Gene3D G3DSA:3.50.50.60 5 171 3.0E-4 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS12945 8093dd22d2bdb82f679c13c6f503dcbe 184 Pfam PF13223 Protein of unknown function (DUF4031) 3 75 7.7E-19 T 28-03-2018 IPR025109 Domain of unknown function DUF4031 CFK41_RS06500 bcdca72e827556d16dcddf99dde307be 305 Pfam PF02687 FtsX-like permease family 209 296 9.9E-7 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CFK41_RS06500 bcdca72e827556d16dcddf99dde307be 305 PIRSF PIRSF003097 1 305 2.7E-60 T 28-03-2018 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 CFK41_RS11780 e0bdb49fdae442d1483e57bdb1046b8b 195 Gene3D G3DSA:3.40.50.300 12 195 2.2E-11 T 28-03-2018 CFK41_RS11780 e0bdb49fdae442d1483e57bdb1046b8b 195 SUPERFAMILY SSF52540 14 193 4.31E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS11845 f1fe789bd48a0cc78e58c4def12f6078 312 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 227 2.6E-104 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS11845 f1fe789bd48a0cc78e58c4def12f6078 312 PRINTS PR00395 Ribosomal protein S2 signature 87 104 1.1E-37 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS11845 f1fe789bd48a0cc78e58c4def12f6078 312 PRINTS PR00395 Ribosomal protein S2 signature 176 187 1.1E-37 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS11845 f1fe789bd48a0cc78e58c4def12f6078 312 PRINTS PR00395 Ribosomal protein S2 signature 6 24 1.1E-37 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS11845 f1fe789bd48a0cc78e58c4def12f6078 312 PRINTS PR00395 Ribosomal protein S2 signature 159 176 1.1E-37 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS11845 f1fe789bd48a0cc78e58c4def12f6078 312 PRINTS PR00395 Ribosomal protein S2 signature 37 46 1.1E-37 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS11845 f1fe789bd48a0cc78e58c4def12f6078 312 PRINTS PR00395 Ribosomal protein S2 signature 197 211 1.1E-37 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS11845 f1fe789bd48a0cc78e58c4def12f6078 312 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CFK41_RS11845 f1fe789bd48a0cc78e58c4def12f6078 312 SUPERFAMILY SSF52313 6 231 4.05E-90 T 28-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain CFK41_RS11845 f1fe789bd48a0cc78e58c4def12f6078 312 Pfam PF00318 Ribosomal protein S2 9 225 4.4E-94 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS11845 f1fe789bd48a0cc78e58c4def12f6078 312 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 226 41.122 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS11845 f1fe789bd48a0cc78e58c4def12f6078 312 Gene3D G3DSA:3.40.50.10490 5 299 1.1E-96 T 28-03-2018 CFK41_RS02170 17cd6dddb08435c7f7b7561a70e12c4c 197 SUPERFAMILY SSF111304 3 197 3.66E-71 T 28-03-2018 IPR023627 Recombination protein RecR CFK41_RS02170 17cd6dddb08435c7f7b7561a70e12c4c 197 SMART SM00278 11 30 0.0081 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CFK41_RS02170 17cd6dddb08435c7f7b7561a70e12c4c 197 TIGRFAM TIGR00615 recR: recombination protein RecR 2 195 3.6E-79 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CFK41_RS02170 17cd6dddb08435c7f7b7561a70e12c4c 197 Hamap MF_00017 Recombination protein RecR [recR]. 1 197 98.324 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CFK41_RS02170 17cd6dddb08435c7f7b7561a70e12c4c 197 Pfam PF13662 Toprim domain 80 170 2.7E-22 T 28-03-2018 IPR006171 TOPRIM domain CFK41_RS02170 17cd6dddb08435c7f7b7561a70e12c4c 197 Pfam PF00633 Helix-hairpin-helix motif 2 27 6.4E-6 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CFK41_RS02170 17cd6dddb08435c7f7b7561a70e12c4c 197 Pfam PF02132 RecR protein 39 76 4.7E-15 T 28-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger CFK41_RS02170 17cd6dddb08435c7f7b7561a70e12c4c 197 Gene3D G3DSA:3.40.1360.10 76 169 3.6E-36 T 28-03-2018 CFK41_RS02170 17cd6dddb08435c7f7b7561a70e12c4c 197 SMART SM00493 79 164 8.8E-10 T 28-03-2018 IPR006171 TOPRIM domain CFK41_RS02170 17cd6dddb08435c7f7b7561a70e12c4c 197 Gene3D G3DSA:1.10.150.20 2 52 9.4E-4 T 28-03-2018 CFK41_RS13405 5589e28ad3016177bb2b7a75ef24070b 103 Pfam PF03992 Antibiotic biosynthesis monooxygenase 3 71 1.2E-15 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CFK41_RS13405 5589e28ad3016177bb2b7a75ef24070b 103 SUPERFAMILY SSF54909 1 94 6.8E-22 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CFK41_RS13405 5589e28ad3016177bb2b7a75ef24070b 103 Gene3D G3DSA:3.30.70.100 1 94 8.0E-18 T 28-03-2018 CFK41_RS06640 b97529a7504b1567357f1492ee56a6d6 180 SUPERFAMILY SSF55811 20 154 2.76E-8 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CFK41_RS06640 b97529a7504b1567357f1492ee56a6d6 180 Pfam PF16262 Domain of unknown function (DUF4916) 10 178 2.0E-75 T 28-03-2018 IPR032582 Protein of unknown function DUF4916 CFK41_RS06640 b97529a7504b1567357f1492ee56a6d6 180 Gene3D G3DSA:3.90.79.10 23 178 6.5E-11 T 28-03-2018 CFK41_RS01905 34648ea722884c93f2c9c2015d425622 354 Gene3D G3DSA:3.20.20.70 37 339 4.1E-44 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS01905 34648ea722884c93f2c9c2015d425622 354 SMART SM00729 61 280 1.8E-4 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CFK41_RS01905 34648ea722884c93f2c9c2015d425622 354 SUPERFAMILY SSF102114 64 277 2.49E-12 T 28-03-2018 CFK41_RS01905 34648ea722884c93f2c9c2015d425622 354 Pfam PF04055 Radical SAM superfamily 65 238 4.1E-13 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CFK41_RS03095 fff847648e996f9e22f87839a1a19fc1 181 SUPERFAMILY SSF51735 26 156 9.35E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS03095 fff847648e996f9e22f87839a1a19fc1 181 Pfam PF13380 CoA binding domain 38 153 9.0E-40 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CFK41_RS03095 fff847648e996f9e22f87839a1a19fc1 181 Gene3D G3DSA:3.40.50.720 34 157 4.1E-35 T 28-03-2018 CFK41_RS03095 fff847648e996f9e22f87839a1a19fc1 181 SMART SM00881 34 127 4.8E-22 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CFK41_RS04350 03849c57dc7bb8dda19bb69348f1ce9b 593 Pfam PF05140 ResB-like family 62 554 2.0E-127 T 28-03-2018 IPR007816 ResB-like domain CFK41_RS09860 eefe5e6ccd8a66506d6133cc62d4b186 558 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 130 303 1.9E-58 T 28-03-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CFK41_RS09860 eefe5e6ccd8a66506d6133cc62d4b186 558 Gene3D G3DSA:1.20.810.10 32 451 1.5E-104 T 28-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 CFK41_RS09860 eefe5e6ccd8a66506d6133cc62d4b186 558 SUPERFAMILY SSF81342 29 309 2.2E-64 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CFK41_RS17025 c90a21e3ef1a3852ed3ff4cc7fbfbc4e 572 Pfam PF00920 Dehydratase family 37 554 5.7E-168 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CFK41_RS17025 c90a21e3ef1a3852ed3ff4cc7fbfbc4e 572 SUPERFAMILY SSF143975 3 369 1.09E-110 T 28-03-2018 CFK41_RS17025 c90a21e3ef1a3852ed3ff4cc7fbfbc4e 572 SUPERFAMILY SSF52016 372 559 4.08E-55 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CFK41_RS17025 c90a21e3ef1a3852ed3ff4cc7fbfbc4e 572 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 120 130 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CFK41_RS15445 2345f6ae1df6aeca1bd98439b0d53cc7 155 Pfam PF12823 Domain of unknown function (DUF3817) 9 96 5.7E-22 T 28-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane CFK41_RS15445 2345f6ae1df6aeca1bd98439b0d53cc7 155 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 11 94 5.2E-22 T 28-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane CFK41_RS03310 6c83110580b55d3c91f98a38b930759a 316 Pfam PF01061 ABC-2 type transporter 73 275 2.7E-11 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CFK41_RS11070 db58fe2d1cb3160770900e13911e75a6 347 Gene3D G3DSA:3.40.50.1820 2 342 1.2E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS11070 db58fe2d1cb3160770900e13911e75a6 347 PIRSF PIRSF006431 1 344 6.0E-83 T 28-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 CFK41_RS11070 db58fe2d1cb3160770900e13911e75a6 347 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 111 125 3.0E-9 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CFK41_RS11070 db58fe2d1cb3160770900e13911e75a6 347 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 62 73 3.0E-9 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CFK41_RS11070 db58fe2d1cb3160770900e13911e75a6 347 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 36 44 3.0E-9 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CFK41_RS11070 db58fe2d1cb3160770900e13911e75a6 347 Pfam PF00561 alpha/beta hydrolase fold 37 168 1.3E-18 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CFK41_RS11070 db58fe2d1cb3160770900e13911e75a6 347 SUPERFAMILY SSF53474 232 327 5.56E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS11070 db58fe2d1cb3160770900e13911e75a6 347 SUPERFAMILY SSF53474 12 194 5.56E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS01705 7501ddeea8039513f77b93192fc755e3 238 SUPERFAMILY SSF52266 8 225 6.87E-45 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CFK41_RS01705 7501ddeea8039513f77b93192fc755e3 238 Gene3D G3DSA:3.40.50.1110 8 237 1.1E-29 T 28-03-2018 CFK41_RS01705 7501ddeea8039513f77b93192fc755e3 238 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 13 209 3.3E-14 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CFK41_RS14025 bc786af8baba571aa7ffe8b1e6284d94 249 Pfam PF11139 Sap, sulfolipid-1-addressing protein 13 236 1.2E-16 T 28-03-2018 IPR021315 Glycolipid exporter Gap/Sap CFK41_RS12290 e66c225d2d438080d54ba072b3831f51 244 SUPERFAMILY SSF53448 35 225 1.58E-14 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS12290 e66c225d2d438080d54ba072b3831f51 244 Gene3D G3DSA:3.90.550.10 32 228 8.6E-17 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS12290 e66c225d2d438080d54ba072b3831f51 244 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 58 227 3.9E-14 T 28-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CFK41_RS13665 af35b63fc1ede73de5d96c470aa1db24 430 SUPERFAMILY SSF56219 170 427 3.72E-21 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS13665 af35b63fc1ede73de5d96c470aa1db24 430 SUPERFAMILY SSF56219 64 137 3.72E-21 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS13665 af35b63fc1ede73de5d96c470aa1db24 430 Gene3D G3DSA:3.60.10.10 62 430 1.9E-22 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS13665 af35b63fc1ede73de5d96c470aa1db24 430 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 69 419 8.4E-24 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS16790 2a5ee3b9e56772c658d241f7d2b56fa3 204 Pfam PF06821 Serine hydrolase 16 201 6.1E-22 T 28-03-2018 IPR010662 Putative hydrolase RBBP9/YdeN GO:0016787 CFK41_RS16790 2a5ee3b9e56772c658d241f7d2b56fa3 204 SUPERFAMILY SSF53474 16 200 6.25E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS16790 2a5ee3b9e56772c658d241f7d2b56fa3 204 Gene3D G3DSA:3.40.50.1820 15 204 3.7E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS04215 e902aad59595d14ef9f4253c78ea4963 249 Pfam PF01738 Dienelactone hydrolase family 17 243 2.9E-40 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 CFK41_RS04215 e902aad59595d14ef9f4253c78ea4963 249 SUPERFAMILY SSF53474 4 245 6.89E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS04215 e902aad59595d14ef9f4253c78ea4963 249 Gene3D G3DSA:3.40.50.1820 1 243 5.5E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS17610 6a632dafb6a4b220bc04d41e83c369d6 384 SUPERFAMILY SSF46955 33 138 3.62E-13 T 28-03-2018 IPR009061 Putative DNA-binding domain CFK41_RS17610 6a632dafb6a4b220bc04d41e83c369d6 384 Gene3D G3DSA:1.10.1660.10 23 144 1.1E-13 T 28-03-2018 CFK41_RS17610 6a632dafb6a4b220bc04d41e83c369d6 384 Pfam PF00376 MerR family regulatory protein 35 73 5.7E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS17610 6a632dafb6a4b220bc04d41e83c369d6 384 Gene3D G3DSA:3.10.150.10 145 384 1.3E-17 T 28-03-2018 CFK41_RS17610 6a632dafb6a4b220bc04d41e83c369d6 384 SMART SM00422 34 104 0.003 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CFK41_RS03780 5e597a4d56b2ed84d85a5d6172b5a206 191 SUPERFAMILY SSF46689 11 81 1.85E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS03780 5e597a4d56b2ed84d85a5d6172b5a206 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 1.5E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS03780 5e597a4d56b2ed84d85a5d6172b5a206 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 1.5E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS03780 5e597a4d56b2ed84d85a5d6172b5a206 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 6.1E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS03780 5e597a4d56b2ed84d85a5d6172b5a206 191 Gene3D G3DSA:1.10.357.10 7 189 4.9E-31 T 28-03-2018 CFK41_RS03780 5e597a4d56b2ed84d85a5d6172b5a206 191 SUPERFAMILY SSF48498 113 171 1.28E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CFK41_RS08945 0b55600e960b4119dbee8a72c8fe6925 300 SUPERFAMILY SSF159659 6 265 1.01E-61 T 28-03-2018 CFK41_RS08945 0b55600e960b4119dbee8a72c8fe6925 300 Pfam PF09754 PAC2 family 30 242 6.0E-30 T 28-03-2018 IPR019151 Proteasome assembly chaperone 2 CFK41_RS08945 0b55600e960b4119dbee8a72c8fe6925 300 Gene3D G3DSA:1.10.287.100 225 265 5.1E-9 T 28-03-2018 CFK41_RS08945 0b55600e960b4119dbee8a72c8fe6925 300 PIRSF PIRSF028754 5 299 3.7E-65 T 28-03-2018 IPR008492 Protein of unknown function DUF774 CFK41_RS06385 8163f505e76221f708fa8a60f36fee4b 79 Pfam PF12728 Helix-turn-helix domain 9 55 3.1E-9 T 28-03-2018 CFK41_RS06385 8163f505e76221f708fa8a60f36fee4b 79 Gene3D G3DSA:1.10.10.10 8 75 1.5E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS06385 8163f505e76221f708fa8a60f36fee4b 79 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 10 54 1.1E-7 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CFK41_RS09595 6ba4c82766d40a535089fac2d097567d 475 SUPERFAMILY SSF101960 41 472 6.41E-139 T 28-03-2018 CFK41_RS09595 6ba4c82766d40a535089fac2d097567d 475 Pfam PF01458 Uncharacterized protein family (UPF0051) 221 446 2.2E-72 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CFK41_RS09595 6ba4c82766d40a535089fac2d097567d 475 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 19 466 5.2E-220 T 28-03-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 CFK41_RS10575 d625a72dd2846c3847e5150711f71202 439 Pfam PF07730 Histidine kinase 225 292 1.1E-13 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CFK41_RS10575 d625a72dd2846c3847e5150711f71202 439 SUPERFAMILY SSF55874 301 420 3.87E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS10575 d625a72dd2846c3847e5150711f71202 439 Gene3D G3DSA:3.30.565.10 289 427 1.6E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS10575 d625a72dd2846c3847e5150711f71202 439 Pfam PF13796 Putative sensor 31 196 5.6E-7 T 28-03-2018 IPR025828 Putative sensor domain CFK41_RS06750 eb06b50fb2458ab812a3f1b67390ebb2 279 SMART SM00954 86 209 1.1E-37 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CFK41_RS06750 eb06b50fb2458ab812a3f1b67390ebb2 279 Gene3D G3DSA:3.30.460.10 40 190 5.0E-36 T 28-03-2018 CFK41_RS06750 eb06b50fb2458ab812a3f1b67390ebb2 279 Pfam PF04607 Region found in RelA / SpoT proteins 86 206 4.2E-33 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CFK41_RS06750 eb06b50fb2458ab812a3f1b67390ebb2 279 Gene3D G3DSA:1.10.287.860 192 239 3.2E-15 T 28-03-2018 CFK41_RS06750 eb06b50fb2458ab812a3f1b67390ebb2 279 SUPERFAMILY SSF81301 47 239 1.31E-52 T 28-03-2018 CFK41_RS07415 7f9639a63478a99cdc54a1f86d1295b8 65 SUPERFAMILY SSF143800 3 60 7.26E-23 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS07415 7f9639a63478a99cdc54a1f86d1295b8 65 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 2 63 16.651 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS07415 7f9639a63478a99cdc54a1f86d1295b8 65 Pfam PF00830 Ribosomal L28 family 6 59 5.9E-21 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS07415 7f9639a63478a99cdc54a1f86d1295b8 65 Gene3D G3DSA:2.30.170.40 3 64 2.4E-22 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS07415 7f9639a63478a99cdc54a1f86d1295b8 65 TIGRFAM TIGR00009 L28: ribosomal protein bL28 3 57 2.3E-22 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS09000 4ae7c4cacbd14443b213d607c32377d0 110 Pfam PF06947 Protein of unknown function (DUF1290) 21 108 2.6E-33 T 28-03-2018 IPR009709 Protein of unknown function DUF1290 CFK41_RS09000 4ae7c4cacbd14443b213d607c32377d0 110 PIRSF PIRSF018579 1 110 2.6E-44 T 28-03-2018 IPR009709 Protein of unknown function DUF1290 CFK41_RS09295 1af4e3d5f7cd904f8b83c1859edb7be2 214 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 11 186 3.7E-24 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CFK41_RS09295 1af4e3d5f7cd904f8b83c1859edb7be2 214 Gene3D G3DSA:3.40.50.300 1 204 1.4E-25 T 28-03-2018 CFK41_RS09295 1af4e3d5f7cd904f8b83c1859edb7be2 214 SUPERFAMILY SSF52540 7 199 9.71E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS09295 1af4e3d5f7cd904f8b83c1859edb7be2 214 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 7 205 20.001 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CFK41_RS09295 1af4e3d5f7cd904f8b83c1859edb7be2 214 Pfam PF01121 Dephospho-CoA kinase 10 185 3.2E-38 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CFK41_RS02630 57597871af0cf963ad7effc05841ac94 126 SUPERFAMILY SSF54427 7 108 6.44E-16 T 28-03-2018 IPR032710 NTF2-like domain CFK41_RS02630 57597871af0cf963ad7effc05841ac94 126 Pfam PF12680 SnoaL-like domain 9 102 1.3E-10 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CFK41_RS02630 57597871af0cf963ad7effc05841ac94 126 Gene3D G3DSA:3.10.450.50 6 120 7.7E-16 T 28-03-2018 CFK41_RS16915 79f04dd0015e2ffce2c83992c8496324 304 SUPERFAMILY SSF51569 36 302 3.41E-34 T 28-03-2018 CFK41_RS16915 79f04dd0015e2ffce2c83992c8496324 304 Gene3D G3DSA:3.20.20.70 9 304 1.7E-70 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS08575 c78a7024f06b98429dc011c3aab939fc 385 Gene3D G3DSA:3.30.160.60 349 385 1.4E-11 T 28-03-2018 CFK41_RS08575 c78a7024f06b98429dc011c3aab939fc 385 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 39 380 29.167 T 28-03-2018 IPR003770 Endolytic murein transglycosylase CFK41_RS08575 c78a7024f06b98429dc011c3aab939fc 385 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 82 379 2.0E-45 T 28-03-2018 IPR003770 Endolytic murein transglycosylase CFK41_RS08575 c78a7024f06b98429dc011c3aab939fc 385 Pfam PF02618 YceG-like family 85 376 4.8E-64 T 28-03-2018 IPR003770 Endolytic murein transglycosylase CFK41_RS14370 96ef9f0a4b12239d684e9bdba9a8854e 540 SUPERFAMILY SSF51445 117 332 6.4E-8 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS14370 96ef9f0a4b12239d684e9bdba9a8854e 540 Gene3D G3DSA:3.20.20.80 111 410 2.2E-8 T 28-03-2018 CFK41_RS02455 725b38852df1774ff1571c156fa90aab 951 Pfam PF04230 Polysaccharide pyruvyl transferase 383 690 1.2E-25 T 28-03-2018 IPR007345 Polysaccharide pyruvyl transferase CFK41_RS02455 725b38852df1774ff1571c156fa90aab 951 Gene3D G3DSA:3.40.50.2000 11 326 3.9E-8 T 28-03-2018 CFK41_RS02455 725b38852df1774ff1571c156fa90aab 951 Pfam PF13524 Glycosyl transferases group 1 259 338 1.3E-18 T 28-03-2018 CFK41_RS02455 725b38852df1774ff1571c156fa90aab 951 Gene3D G3DSA:3.40.50.2000 563 757 7.5E-5 T 28-03-2018 CFK41_RS15815 049f3fe6111345a021098c235c403abd 208 SUPERFAMILY SSF53756 55 160 7.22E-8 T 28-03-2018 CFK41_RS15815 049f3fe6111345a021098c235c403abd 208 Gene3D G3DSA:3.40.50.2000 2 206 1.5E-14 T 28-03-2018 CFK41_RS15815 049f3fe6111345a021098c235c403abd 208 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 75 156 1.2E-8 T 28-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CFK41_RS03000 9de44ddc8870eb61594af962a6703f33 481 Pfam PF00905 Penicillin binding protein transpeptidase domain 155 476 3.0E-69 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CFK41_RS03000 9de44ddc8870eb61594af962a6703f33 481 Gene3D G3DSA:3.90.1310.10 17 129 1.3E-14 T 28-03-2018 CFK41_RS03000 9de44ddc8870eb61594af962a6703f33 481 Gene3D G3DSA:3.40.710.10 130 481 4.0E-93 T 28-03-2018 CFK41_RS03000 9de44ddc8870eb61594af962a6703f33 481 SUPERFAMILY SSF56601 138 479 1.09E-91 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CFK41_RS04615 1244c05a4fb29883040e4b484ef1b90f 77 Gene3D G3DSA:1.10.287.310 6 69 3.0E-21 T 28-03-2018 CFK41_RS04615 1244c05a4fb29883040e4b484ef1b90f 77 SUPERFAMILY SSF46561 8 69 1.27E-20 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04615 1244c05a4fb29883040e4b484ef1b90f 77 TIGRFAM TIGR00012 L29: ribosomal protein uL29 10 65 5.8E-20 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04615 1244c05a4fb29883040e4b484ef1b90f 77 Pfam PF00831 Ribosomal L29 protein 10 65 1.4E-23 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS04615 1244c05a4fb29883040e4b484ef1b90f 77 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 6 65 15.906 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CFK41_RS03760 812d29674604ef166600628d958a6a1d 237 Pfam PF13419 Haloacid dehalogenase-like hydrolase 28 204 1.7E-23 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS03760 812d29674604ef166600628d958a6a1d 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 148 164 4.4E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CFK41_RS03760 812d29674604ef166600628d958a6a1d 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 166 186 4.4E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CFK41_RS03760 812d29674604ef166600628d958a6a1d 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 25 36 4.4E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CFK41_RS03760 812d29674604ef166600628d958a6a1d 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 117 130 4.4E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CFK41_RS03760 812d29674604ef166600628d958a6a1d 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 193 206 4.4E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CFK41_RS03760 812d29674604ef166600628d958a6a1d 237 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 101 204 7.8E-15 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CFK41_RS03760 812d29674604ef166600628d958a6a1d 237 Gene3D G3DSA:3.40.50.1000 98 237 1.4E-26 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS03760 812d29674604ef166600628d958a6a1d 237 SUPERFAMILY SSF56784 26 212 2.95E-43 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS03760 812d29674604ef166600628d958a6a1d 237 Gene3D G3DSA:1.10.150.240 38 97 2.9E-6 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CFK41_RS08750 43abae93ef092322a25de5f3b981a6bb 270 Gene3D G3DSA:2.30.40.10 22 82 2.3E-10 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS08750 43abae93ef092322a25de5f3b981a6bb 270 Gene3D G3DSA:3.20.20.140 83 162 5.7E-4 T 28-03-2018 CFK41_RS08750 43abae93ef092322a25de5f3b981a6bb 270 Gene3D G3DSA:2.30.40.10 163 260 6.5E-7 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS08750 43abae93ef092322a25de5f3b981a6bb 270 SUPERFAMILY SSF51338 195 215 1.13E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS08750 43abae93ef092322a25de5f3b981a6bb 270 SUPERFAMILY SSF51338 25 80 1.13E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS03245 bd2d42c0cd21d724e811ae07a3d2154e 293 SUPERFAMILY SSF47413 34 83 2.75E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS03245 bd2d42c0cd21d724e811ae07a3d2154e 293 Gene3D G3DSA:1.10.260.40 1 100 1.3E-15 T 28-03-2018 CFK41_RS03245 bd2d42c0cd21d724e811ae07a3d2154e 293 SMART SM00530 14 86 2.0E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CFK41_RS03245 bd2d42c0cd21d724e811ae07a3d2154e 293 Pfam PF13560 Helix-turn-helix domain 10 89 7.4E-19 T 28-03-2018 CFK41_RS11700 5f984be39b4609e390e08d128c8f3523 255 Gene3D G3DSA:3.40.50.720 8 129 8.5E-27 T 28-03-2018 CFK41_RS11700 5f984be39b4609e390e08d128c8f3523 255 SUPERFAMILY SSF55347 114 224 3.27E-35 T 28-03-2018 CFK41_RS11700 5f984be39b4609e390e08d128c8f3523 255 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 135 152 - T 28-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CFK41_RS11700 5f984be39b4609e390e08d128c8f3523 255 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 48 244 2.1E-48 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CFK41_RS11700 5f984be39b4609e390e08d128c8f3523 255 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 116 243 6.4E-27 T 28-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CFK41_RS11700 5f984be39b4609e390e08d128c8f3523 255 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 10 113 2.4E-23 T 28-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CFK41_RS11700 5f984be39b4609e390e08d128c8f3523 255 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 9 253 26.874 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CFK41_RS11700 5f984be39b4609e390e08d128c8f3523 255 Gene3D G3DSA:3.30.360.10 130 221 1.0E-29 T 28-03-2018 CFK41_RS11700 5f984be39b4609e390e08d128c8f3523 255 SUPERFAMILY SSF51735 8 139 5.05E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS11700 5f984be39b4609e390e08d128c8f3523 255 PIRSF PIRSF000161 7 254 2.3E-56 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CFK41_RS16925 f0d5095cda69cf4cd7d681d1e68229aa 129 Pfam PF14552 Tautomerase enzyme 38 118 5.8E-25 T 28-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CFK41_RS16925 f0d5095cda69cf4cd7d681d1e68229aa 129 Gene3D G3DSA:3.30.429.10 1 129 1.3E-25 T 28-03-2018 CFK41_RS16925 f0d5095cda69cf4cd7d681d1e68229aa 129 SUPERFAMILY SSF55331 2 128 1.27E-29 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily CFK41_RS00270 c4266d23a51585f6ffcde26de58aa078 149 SUPERFAMILY SSF55729 11 142 2.4E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS00270 c4266d23a51585f6ffcde26de58aa078 149 Pfam PF00583 Acetyltransferase (GNAT) family 38 137 1.8E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS00270 c4266d23a51585f6ffcde26de58aa078 149 Gene3D G3DSA:3.40.630.30 7 148 1.4E-19 T 28-03-2018 CFK41_RS08250 10940d9a842adc9e219b0ed3df208144 269 Gene3D G3DSA:3.40.1180.10 18 259 2.1E-84 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CFK41_RS08250 10940d9a842adc9e219b0ed3df208144 269 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 202 219 - T 28-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 CFK41_RS08250 10940d9a842adc9e219b0ed3df208144 269 SUPERFAMILY SSF64005 28 252 1.96E-81 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CFK41_RS08250 10940d9a842adc9e219b0ed3df208144 269 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 29 257 36.566 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CFK41_RS08250 10940d9a842adc9e219b0ed3df208144 269 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 29 256 1.5E-72 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CFK41_RS08250 10940d9a842adc9e219b0ed3df208144 269 Pfam PF01255 Putative undecaprenyl diphosphate synthase 36 256 5.6E-71 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CFK41_RS17400 7c39af78a6f1f675a3dd9e15e593c3ac 530 Gene3D G3DSA:3.90.420.10 214 422 3.8E-52 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CFK41_RS17400 7c39af78a6f1f675a3dd9e15e593c3ac 530 Pfam PF00174 Oxidoreductase molybdopterin binding domain 252 399 5.0E-39 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CFK41_RS17400 7c39af78a6f1f675a3dd9e15e593c3ac 530 SUPERFAMILY SSF81296 416 529 1.68E-22 T 28-03-2018 IPR014756 Immunoglobulin E-set CFK41_RS17400 7c39af78a6f1f675a3dd9e15e593c3ac 530 SUPERFAMILY SSF56524 236 423 6.15E-55 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CFK41_RS17400 7c39af78a6f1f675a3dd9e15e593c3ac 530 Gene3D G3DSA:2.60.40.650 423 530 1.5E-22 T 28-03-2018 CFK41_RS07150 99235fa52effda2da369c222b3207f5e 400 Pfam PF00266 Aminotransferase class-V 10 380 6.1E-46 T 28-03-2018 IPR000192 Aminotransferase class V domain CFK41_RS07150 99235fa52effda2da369c222b3207f5e 400 PIRSF PIRSF005572 6 394 3.6E-86 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CFK41_RS07150 99235fa52effda2da369c222b3207f5e 400 SUPERFAMILY SSF53383 8 388 2.24E-81 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS07150 99235fa52effda2da369c222b3207f5e 400 Gene3D G3DSA:3.40.640.10 21 269 3.0E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS07150 99235fa52effda2da369c222b3207f5e 400 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 206 225 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CFK41_RS07150 99235fa52effda2da369c222b3207f5e 400 Gene3D G3DSA:3.90.1150.10 276 395 7.0E-32 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS01720 7901bbdff650e6970dcbfc6e1bdda9ba 332 SUPERFAMILY SSF161098 88 317 9.42E-49 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01720 7901bbdff650e6970dcbfc6e1bdda9ba 332 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 322 3.3E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01720 7901bbdff650e6970dcbfc6e1bdda9ba 332 Gene3D G3DSA:1.10.3720.10 44 331 4.4E-41 T 28-03-2018 CFK41_RS06530 81fafa45aa21269199eb9d556255c2b1 315 SUPERFAMILY SSF56112 48 277 2.42E-30 T 28-03-2018 IPR011009 Protein kinase-like domain CFK41_RS06530 81fafa45aa21269199eb9d556255c2b1 315 Gene3D G3DSA:3.30.200.20 24 119 5.9E-4 T 28-03-2018 CFK41_RS06530 81fafa45aa21269199eb9d556255c2b1 315 Gene3D G3DSA:3.90.1200.10 120 302 1.3E-19 T 28-03-2018 CFK41_RS06530 81fafa45aa21269199eb9d556255c2b1 315 Pfam PF01636 Phosphotransferase enzyme family 50 267 3.8E-24 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CFK41_RS16705 90e264167aa617d6bdd87591ceaaca11 279 SUPERFAMILY SSF51735 1 279 5.44E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS16705 90e264167aa617d6bdd87591ceaaca11 279 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 216 4.1E-21 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CFK41_RS16705 90e264167aa617d6bdd87591ceaaca11 279 Gene3D G3DSA:3.40.50.720 1 279 6.3E-39 T 28-03-2018 CFK41_RS11415 fcc7fce033ce58dbd63bba21b1cac60b 402 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 242 374 1.1E-14 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CFK41_RS11415 fcc7fce033ce58dbd63bba21b1cac60b 402 SUPERFAMILY SSF47203 232 392 4.51E-18 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CFK41_RS11415 fcc7fce033ce58dbd63bba21b1cac60b 402 Gene3D G3DSA:1.20.140.10 212 401 2.6E-21 T 28-03-2018 CFK41_RS11415 fcc7fce033ce58dbd63bba21b1cac60b 402 PIRSF PIRSF016578 3 398 2.3E-33 T 28-03-2018 CFK41_RS11415 fcc7fce033ce58dbd63bba21b1cac60b 402 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 19 92 3.6E-8 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CFK41_RS11415 fcc7fce033ce58dbd63bba21b1cac60b 402 Gene3D G3DSA:1.10.540.10 12 114 1.1E-13 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CFK41_RS11415 fcc7fce033ce58dbd63bba21b1cac60b 402 SUPERFAMILY SSF56645 13 219 6.02E-36 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CFK41_RS11415 fcc7fce033ce58dbd63bba21b1cac60b 402 Gene3D G3DSA:2.40.110.10 115 211 1.9E-16 T 28-03-2018 CFK41_RS10645 66cb2d269be48ca43435d2645c7017ee 307 Gene3D G3DSA:1.10.3720.10 29 295 3.8E-43 T 28-03-2018 CFK41_RS10645 66cb2d269be48ca43435d2645c7017ee 307 SUPERFAMILY SSF161098 34 307 4.49E-65 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS10645 66cb2d269be48ca43435d2645c7017ee 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 133 301 5.8E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS16495 13d4968990eac281352694b78f03e69a 224 SUPERFAMILY SSF109854 2 153 2.66E-9 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CFK41_RS16495 13d4968990eac281352694b78f03e69a 224 Gene3D G3DSA:1.20.120.450 1 153 2.4E-17 T 28-03-2018 CFK41_RS16495 13d4968990eac281352694b78f03e69a 224 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 7 149 4.3E-17 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CFK41_RS03295 9f58644c1a856da390a38f41035e85f7 580 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 372 485 2.2E-9 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 CFK41_RS03295 9f58644c1a856da390a38f41035e85f7 580 SUPERFAMILY SSF53756 298 545 1.22E-5 T 28-03-2018 CFK41_RS08390 69c4113e33cfe8334d60e787b3639f27 315 SUPERFAMILY SSF52151 2 120 3.4E-63 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CFK41_RS08390 69c4113e33cfe8334d60e787b3639f27 315 SUPERFAMILY SSF52151 182 305 3.4E-63 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CFK41_RS08390 69c4113e33cfe8334d60e787b3639f27 315 Gene3D G3DSA:3.30.70.250 138 183 1.6E-11 T 28-03-2018 CFK41_RS08390 69c4113e33cfe8334d60e787b3639f27 315 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 305 2.5E-21 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CFK41_RS08390 69c4113e33cfe8334d60e787b3639f27 315 SUPERFAMILY SSF55048 128 178 1.44E-10 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CFK41_RS08390 69c4113e33cfe8334d60e787b3639f27 315 Pfam PF00698 Acyl transferase domain 35 283 3.8E-20 T 28-03-2018 IPR014043 Acyl transferase CFK41_RS08390 69c4113e33cfe8334d60e787b3639f27 315 Gene3D G3DSA:3.40.366.10 184 304 8.4E-28 T 28-03-2018 CFK41_RS08390 69c4113e33cfe8334d60e787b3639f27 315 Gene3D G3DSA:3.40.366.10 1 137 6.8E-26 T 28-03-2018 CFK41_RS13060 482cfbb401896a521da484921a388f1f 322 Gene3D G3DSA:3.20.20.30 1 321 1.4E-60 T 28-03-2018 CFK41_RS13060 482cfbb401896a521da484921a388f1f 322 Pfam PF00296 Luciferase-like monooxygenase 1 293 1.9E-36 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CFK41_RS13060 482cfbb401896a521da484921a388f1f 322 SUPERFAMILY SSF51679 1 315 5.89E-58 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CFK41_RS13060 482cfbb401896a521da484921a388f1f 322 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 3 315 2.6E-86 T 28-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 CFK41_RS16120 6b801177b6c33d60d1a9475ef6685da4 94 SUPERFAMILY SSF54909 1 87 2.52E-17 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CFK41_RS16120 6b801177b6c33d60d1a9475ef6685da4 94 Gene3D G3DSA:3.30.70.1060 1 88 2.4E-16 T 28-03-2018 CFK41_RS16120 6b801177b6c33d60d1a9475ef6685da4 94 Pfam PF03795 YCII-related domain 9 85 9.6E-9 T 28-03-2018 IPR005545 YCII-related CFK41_RS11560 197b7510da32ea6e28f05718d137c9be 285 Gene3D G3DSA:3.40.50.150 25 285 8.0E-29 T 28-03-2018 CFK41_RS11560 197b7510da32ea6e28f05718d137c9be 285 SUPERFAMILY SSF53335 92 254 9.23E-25 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS03250 5e21e97a70310f3c47993bf44f1446a9 126 SUPERFAMILY SSF46767 15 69 5.89E-12 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CFK41_RS03250 5e21e97a70310f3c47993bf44f1446a9 126 Gene3D G3DSA:1.10.10.10 12 114 3.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS03250 5e21e97a70310f3c47993bf44f1446a9 126 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 16 69 4.1E-11 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CFK41_RS06425 d6f891fba2a6a00a56de0558d3ecc57f 839 Pfam PF02687 FtsX-like permease family 740 830 1.6E-11 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CFK41_RS06425 d6f891fba2a6a00a56de0558d3ecc57f 839 Pfam PF02687 FtsX-like permease family 285 379 4.8E-8 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CFK41_RS06425 d6f891fba2a6a00a56de0558d3ecc57f 839 Pfam PF12704 MacB-like periplasmic core domain 18 221 7.6E-12 T 28-03-2018 IPR025857 MacB-like periplasmic core domain CFK41_RS04665 8d6b09eb72e9d702f94cc815858d270b 128 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 18 128 1.1E-37 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS04665 8d6b09eb72e9d702f94cc815858d270b 128 SUPERFAMILY SSF53137 15 126 2.4E-46 T 28-03-2018 CFK41_RS04665 8d6b09eb72e9d702f94cc815858d270b 128 Gene3D G3DSA:3.30.420.100 4 128 1.2E-36 T 28-03-2018 CFK41_RS04665 8d6b09eb72e9d702f94cc815858d270b 128 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 14 128 26.797 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS04665 8d6b09eb72e9d702f94cc815858d270b 128 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 15 128 1.3E-46 T 28-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS05705 7441165ec998b37a0acb4e376a2af6dc 685 Pfam PF05425 Copper resistance protein D 228 319 7.1E-15 T 28-03-2018 IPR008457 Copper resistance protein D GO:0016021 CFK41_RS05705 7441165ec998b37a0acb4e376a2af6dc 685 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 376 618 2.8E-67 T 28-03-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related CFK41_RS11735 ef3fc3da46c5abe8d3724e2e3ad6b6b4 160 Pfam PF02033 Ribosome-binding factor A 6 109 2.7E-25 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CFK41_RS11735 ef3fc3da46c5abe8d3724e2e3ad6b6b4 160 Gene3D G3DSA:3.30.300.20 4 116 3.7E-28 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CFK41_RS11735 ef3fc3da46c5abe8d3724e2e3ad6b6b4 160 SUPERFAMILY SSF89919 1 112 3.92E-29 T 28-03-2018 IPR023799 Ribosome-binding factor A domain CFK41_RS11735 ef3fc3da46c5abe8d3724e2e3ad6b6b4 160 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 2 116 18.453 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CFK41_RS11735 ef3fc3da46c5abe8d3724e2e3ad6b6b4 160 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 111 2.5E-22 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CFK41_RS11735 ef3fc3da46c5abe8d3724e2e3ad6b6b4 160 ProSitePatterns PS01319 Ribosome-binding factor A signature. 75 96 - T 28-03-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 CFK41_RS11735 ef3fc3da46c5abe8d3724e2e3ad6b6b4 160 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 10 96 4.0E-31 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CFK41_RS09800 5f76aa517ac97974c25abf9cdaccc2aa 476 SUPERFAMILY SSF51569 38 473 1.54E-185 T 28-03-2018 CFK41_RS09800 5f76aa517ac97974c25abf9cdaccc2aa 476 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 39 474 6.1E-201 T 28-03-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CFK41_RS09800 5f76aa517ac97974c25abf9cdaccc2aa 476 Gene3D G3DSA:3.20.20.70 273 414 2.4E-5 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CFK41_RS09800 5f76aa517ac97974c25abf9cdaccc2aa 476 Pfam PF01474 Class-II DAHP synthetase family 41 470 2.6E-186 T 28-03-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CFK41_RS12210 b14be0dc13acae06c3af0efff2b23133 179 Pfam PF02559 CarD-like/TRCF domain 14 100 1.5E-5 T 28-03-2018 IPR003711 CarD-like/TRCF domain CFK41_RS12210 b14be0dc13acae06c3af0efff2b23133 179 SUPERFAMILY SSF141259 14 73 6.93E-6 T 28-03-2018 IPR003711 CarD-like/TRCF domain CFK41_RS12210 b14be0dc13acae06c3af0efff2b23133 179 SMART SM01058 12 124 0.0011 T 28-03-2018 IPR003711 CarD-like/TRCF domain CFK41_RS11455 6aa4800e830580999cf04ee1dc434f19 243 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 5 32 1.2E-10 T 28-03-2018 IPR019933 DivIVA domain CFK41_RS11455 6aa4800e830580999cf04ee1dc434f19 243 Pfam PF05103 DivIVA protein 4 64 9.2E-9 T 28-03-2018 IPR007793 DivIVA family CFK41_RS11455 6aa4800e830580999cf04ee1dc434f19 243 Gene3D G3DSA:1.20.58.60 23 232 1.4E-4 T 28-03-2018 CFK41_RS13375 0b9974094c3107c681c59fe3d4360436 239 Pfam PF13398 Peptidase M50B-like 29 226 2.6E-42 T 28-03-2018 CFK41_RS12095 99404a28fc77da8e86c877e0ea86b336 446 Hamap MF_00423 L-seryl-tRNA(Sec) selenium transferase [selA]. 1 441 156.979 T 28-03-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CFK41_RS12095 99404a28fc77da8e86c877e0ea86b336 446 Gene3D G3DSA:3.40.640.10 46 339 8.8E-28 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS12095 99404a28fc77da8e86c877e0ea86b336 446 TIGRFAM TIGR00474 selA: L-seryl-tRNA(Sec) selenium transferase 16 435 6.2E-120 T 28-03-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CFK41_RS12095 99404a28fc77da8e86c877e0ea86b336 446 Pfam PF03841 L-seryl-tRNA selenium transferase 82 423 2.8E-93 T 28-03-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CFK41_RS12095 99404a28fc77da8e86c877e0ea86b336 446 Pfam PF12390 Selenocysteine synthase N terminal 15 54 6.8E-8 T 28-03-2018 IPR025862 L-seryl-tRNA selenium transferase N-terminal domain KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CFK41_RS12095 99404a28fc77da8e86c877e0ea86b336 446 SUPERFAMILY SSF53383 78 364 1.27E-34 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS00005 0771ff4df3463d923a3b2fefa18dd61d 437 Pfam PF05552 Conserved TM helix 93 138 5.6E-12 T 28-03-2018 IPR008910 Conserved TM helix CFK41_RS00005 0771ff4df3463d923a3b2fefa18dd61d 437 Pfam PF05552 Conserved TM helix 225 272 2.2E-12 T 28-03-2018 IPR008910 Conserved TM helix CFK41_RS07455 3a3d248d984bb108de2a0af359e603ff 126 Pfam PF11528 Protein of unknown function (DUF3224) 6 124 1.1E-29 T 28-03-2018 IPR021607 Protein of unknown function DUF3224 CFK41_RS07455 3a3d248d984bb108de2a0af359e603ff 126 SUPERFAMILY SSF159238 2 125 3.79E-32 T 28-03-2018 IPR023159 SO1590-like domain CFK41_RS07455 3a3d248d984bb108de2a0af359e603ff 126 Gene3D G3DSA:2.40.350.10 1 126 2.7E-33 T 28-03-2018 IPR023159 SO1590-like domain CFK41_RS09675 1ede3775b3b65e714b877acb9d52c523 251 PIRSF PIRSF010219 38 250 2.3E-57 T 28-03-2018 IPR016566 Uncharacterised conserved protein UCP010219 CFK41_RS09675 1ede3775b3b65e714b877acb9d52c523 251 Pfam PF11361 Protein of unknown function (DUF3159) 61 242 3.7E-54 T 28-03-2018 IPR016566 Uncharacterised conserved protein UCP010219 CFK41_RS12465 f6bc62b11b5d9f5bc50f95130519363e 641 Pfam PF01636 Phosphotransferase enzyme family 169 342 1.1E-11 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CFK41_RS12465 f6bc62b11b5d9f5bc50f95130519363e 641 SUPERFAMILY SSF56112 155 366 3.74E-19 T 28-03-2018 IPR011009 Protein kinase-like domain CFK41_RS12465 f6bc62b11b5d9f5bc50f95130519363e 641 Gene3D G3DSA:1.10.510.10 172 374 4.1E-13 T 28-03-2018 CFK41_RS14310 98ecb7c15e96ff00e6d27c7e0e6a9e75 227 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 41 216 2.1E-32 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CFK41_RS07890 190e94316447f2b44a9d4c75051108db 332 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 291 4.7E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS07890 190e94316447f2b44a9d4c75051108db 332 SUPERFAMILY SSF161098 83 271 8.9E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS07890 190e94316447f2b44a9d4c75051108db 332 Gene3D G3DSA:1.10.3720.10 16 280 1.7E-30 T 28-03-2018 CFK41_RS04930 9d395c3deb49239a6c39a8aa26a0a8c4 200 Gene3D G3DSA:3.40.50.300 1 163 2.7E-44 T 28-03-2018 CFK41_RS04930 9d395c3deb49239a6c39a8aa26a0a8c4 200 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 10 129 5.9E-21 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CFK41_RS04930 9d395c3deb49239a6c39a8aa26a0a8c4 200 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 9 125 5.2E-27 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CFK41_RS04930 9d395c3deb49239a6c39a8aa26a0a8c4 200 SUPERFAMILY SSF52540 15 128 1.05E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS15530 b19c305c145adf7a2973908e01dee080 321 Gene3D G3DSA:1.10.260.40 2 81 4.1E-8 T 28-03-2018 CFK41_RS14385 ca8b57d3a3daf9bf9f6ebe1ee985e17e 1072 Pfam PF13086 AAA domain 305 379 2.2E-7 T 28-03-2018 CFK41_RS14385 ca8b57d3a3daf9bf9f6ebe1ee985e17e 1072 Pfam PF13087 AAA domain 709 907 3.7E-26 T 28-03-2018 CFK41_RS14385 ca8b57d3a3daf9bf9f6ebe1ee985e17e 1072 Gene3D G3DSA:3.40.50.300 726 937 9.4E-25 T 28-03-2018 CFK41_RS14385 ca8b57d3a3daf9bf9f6ebe1ee985e17e 1072 SUPERFAMILY SSF52540 710 915 1.5E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS14385 ca8b57d3a3daf9bf9f6ebe1ee985e17e 1072 SUPERFAMILY SSF52540 303 381 1.5E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS14385 ca8b57d3a3daf9bf9f6ebe1ee985e17e 1072 SUPERFAMILY SSF52540 589 653 1.5E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS14385 ca8b57d3a3daf9bf9f6ebe1ee985e17e 1072 Gene3D G3DSA:3.40.50.300 299 725 1.7E-23 T 28-03-2018 CFK41_RS12255 a43b26b33debd4f90acc2f13dc0f5201 349 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 109 251 2.6E-41 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CFK41_RS12255 a43b26b33debd4f90acc2f13dc0f5201 349 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 109 251 1.5E-36 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CFK41_RS06480 89d91d15029d1af68cb6345d9caf6c8f 154 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 18 64 6.2E-11 T 28-03-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal CFK41_RS02665 da0aac5473681bdd0cd22066893b42c1 666 Gene3D G3DSA:3.40.50.1820 157 571 7.6E-7 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS02665 da0aac5473681bdd0cd22066893b42c1 666 SUPERFAMILY SSF53474 160 278 1.4E-7 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS14245 ceecd4ef625c1920e37b9ac92abaf308 673 Gene3D G3DSA:3.40.50.880 349 578 2.6E-17 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS14245 ceecd4ef625c1920e37b9ac92abaf308 673 SUPERFAMILY SSF52317 359 444 1.53E-5 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS14245 ceecd4ef625c1920e37b9ac92abaf308 673 Pfam PF14871 Hypothetical glycosyl hydrolase 6 29 161 2.3E-26 T 28-03-2018 IPR028212 Hypothetical glycosyl hydrolase 6 CFK41_RS14245 ceecd4ef625c1920e37b9ac92abaf308 673 Gene3D G3DSA:3.20.20.80 13 306 2.0E-20 T 28-03-2018 CFK41_RS14245 ceecd4ef625c1920e37b9ac92abaf308 673 SUPERFAMILY SSF51445 80 317 2.57E-18 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS14245 ceecd4ef625c1920e37b9ac92abaf308 673 Pfam PF08532 Beta-galactosidase trimerisation domain 363 442 1.5E-6 T 28-03-2018 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CFK41_RS11880 3deda8d56243e47e17c30cf8c9705f0a 275 Gene3D G3DSA:3.30.420.10 5 226 2.5E-60 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CFK41_RS11880 3deda8d56243e47e17c30cf8c9705f0a 275 SUPERFAMILY SSF53098 21 219 1.0E-48 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CFK41_RS11880 3deda8d56243e47e17c30cf8c9705f0a 275 Pfam PF01351 Ribonuclease HII 26 217 4.1E-33 T 28-03-2018 IPR024567 Ribonuclease HII/HIII domain CFK41_RS15110 25fdbf912af5a1b3aa5159da8569b722 306 SUPERFAMILY SSF161098 28 306 5.61E-56 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS15110 25fdbf912af5a1b3aa5159da8569b722 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 299 1.5E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS15110 25fdbf912af5a1b3aa5159da8569b722 306 Gene3D G3DSA:1.10.3720.10 83 301 1.1E-36 T 28-03-2018 CFK41_RS15260 3b12687da58fe353ec5e900b5dbb5318 91 SUPERFAMILY SSF52794 1 89 5.75E-18 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CFK41_RS15260 3b12687da58fe353ec5e900b5dbb5318 91 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 61 1.7E-10 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CFK41_RS15260 3b12687da58fe353ec5e900b5dbb5318 91 Gene3D G3DSA:3.40.50.2300 1 90 3.5E-17 T 28-03-2018 CFK41_RS14955 09548cc10874e3fda474b88ec7da0f1b 381 Gene3D G3DSA:1.10.3470.10 38 380 2.7E-69 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CFK41_RS14955 09548cc10874e3fda474b88ec7da0f1b 381 Pfam PF01032 FecCD transport family 53 375 2.5E-87 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CFK41_RS14955 09548cc10874e3fda474b88ec7da0f1b 381 SUPERFAMILY SSF81345 38 375 7.06E-77 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CFK41_RS05540 3ed76f9794499c66ccb6a10966ebaaed 394 Pfam PF07690 Major Facilitator Superfamily 13 322 1.0E-28 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS05540 3ed76f9794499c66ccb6a10966ebaaed 394 Gene3D G3DSA:1.20.1250.20 3 194 9.7E-21 T 28-03-2018 CFK41_RS05540 3ed76f9794499c66ccb6a10966ebaaed 394 SUPERFAMILY SSF103473 3 378 5.1E-46 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS05540 3ed76f9794499c66ccb6a10966ebaaed 394 Gene3D G3DSA:1.20.1250.20 195 383 5.3E-11 T 28-03-2018 CFK41_RS13880 f734c54d1d0d0bc799c0b207f36bc431 459 Pfam PF00083 Sugar (and other) transporter 25 434 3.3E-52 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CFK41_RS13880 f734c54d1d0d0bc799c0b207f36bc431 459 Gene3D G3DSA:1.20.1250.20 22 213 1.6E-33 T 28-03-2018 CFK41_RS13880 f734c54d1d0d0bc799c0b207f36bc431 459 ProSitePatterns PS00216 Sugar transport proteins signature 1. 302 318 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CFK41_RS13880 f734c54d1d0d0bc799c0b207f36bc431 459 SUPERFAMILY SSF103473 8 434 7.46E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS13880 f734c54d1d0d0bc799c0b207f36bc431 459 Gene3D G3DSA:1.20.1250.20 228 449 7.7E-23 T 28-03-2018 CFK41_RS01645 f0ed228260a4b7a8dd7e9c609b913b29 305 SUPERFAMILY SSF161098 35 302 4.45E-69 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01645 f0ed228260a4b7a8dd7e9c609b913b29 305 Gene3D G3DSA:1.10.3720.10 25 291 3.7E-37 T 28-03-2018 CFK41_RS01645 f0ed228260a4b7a8dd7e9c609b913b29 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 297 1.1E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS02590 08f2026a083110d863ee800476219f67 175 Gene3D G3DSA:2.60.40.10 79 167 8.7E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS02590 08f2026a083110d863ee800476219f67 175 SUPERFAMILY SSF49265 80 127 4.92E-5 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CFK41_RS01080 74848d28e06035e0dfff3cbd5aeb1d05 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 208 1.5E-11 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01080 74848d28e06035e0dfff3cbd5aeb1d05 216 SUPERFAMILY SSF161098 11 194 3.27E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01080 74848d28e06035e0dfff3cbd5aeb1d05 216 Gene3D G3DSA:1.10.3720.10 7 206 5.7E-18 T 28-03-2018 CFK41_RS06325 c2cf9c34ad74de03647b1ff3a3a0b3da 232 Pfam PF13559 Domain of unknown function (DUF4129) 126 193 1.5E-11 T 28-03-2018 IPR025403 Domain of unknown function DUF4129 CFK41_RS07085 2df0783a067446415eff927e0d643f41 235 Pfam PF01939 Endonuclease NucS 1 235 2.6E-75 T 28-03-2018 IPR002793 Endonuclease NucS CFK41_RS07085 2df0783a067446415eff927e0d643f41 235 Gene3D G3DSA:3.40.1350.10 96 234 5.4E-4 T 28-03-2018 CFK41_RS07085 2df0783a067446415eff927e0d643f41 235 Hamap MF_00722 Endonuclease NucS [nucS]. 1 227 32.374 T 28-03-2018 IPR002793 Endonuclease NucS CFK41_RS05710 14e0ff84cdcac74c737db84279cfed82 528 Pfam PF04235 Protein of unknown function (DUF418) 396 498 2.5E-5 T 28-03-2018 IPR007349 Domain of unknown function DUF418 CFK41_RS05710 14e0ff84cdcac74c737db84279cfed82 528 Pfam PF07786 Protein of unknown function (DUF1624) 75 257 1.1E-8 T 28-03-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-6798695 CFK41_RS01880 73b4b65af5b5cb067fa04323ec509241 147 Gene3D G3DSA:3.40.140.10 6 133 5.1E-10 T 28-03-2018 CFK41_RS01880 73b4b65af5b5cb067fa04323ec509241 147 SUPERFAMILY SSF53927 5 130 4.14E-16 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CFK41_RS00985 8235b4b7f7dd6fa908ea64e723ea5097 270 Gene3D G3DSA:3.40.630.30 39 265 4.6E-20 T 28-03-2018 CFK41_RS00985 8235b4b7f7dd6fa908ea64e723ea5097 270 Pfam PF08445 FR47-like protein 178 260 5.0E-21 T 28-03-2018 IPR013653 FR47-like GO:0016747 CFK41_RS00985 8235b4b7f7dd6fa908ea64e723ea5097 270 SUPERFAMILY SSF55729 147 262 5.67E-17 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS14850 73715b4c210e47ac0b311e6ee5288d1e 545 SUPERFAMILY SSF51338 461 513 5.32E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS14850 73715b4c210e47ac0b311e6ee5288d1e 545 SUPERFAMILY SSF51338 6 58 5.32E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS14850 73715b4c210e47ac0b311e6ee5288d1e 545 Pfam PF07969 Amidohydrolase family 49 505 4.7E-26 T 28-03-2018 IPR013108 Amidohydrolase 3 CFK41_RS14850 73715b4c210e47ac0b311e6ee5288d1e 545 SUPERFAMILY SSF51556 58 284 2.3E-57 T 28-03-2018 IPR032466 Metal-dependent hydrolase CFK41_RS14850 73715b4c210e47ac0b311e6ee5288d1e 545 SUPERFAMILY SSF51556 339 461 2.3E-57 T 28-03-2018 IPR032466 Metal-dependent hydrolase CFK41_RS14850 73715b4c210e47ac0b311e6ee5288d1e 545 Gene3D G3DSA:2.30.40.10 443 518 4.2E-4 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS14850 73715b4c210e47ac0b311e6ee5288d1e 545 Gene3D G3DSA:2.30.40.10 5 71 9.4E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CFK41_RS14850 73715b4c210e47ac0b311e6ee5288d1e 545 Gene3D G3DSA:3.20.20.140 72 442 6.3E-64 T 28-03-2018 CFK41_RS08430 0f5f35d1ec48706ce6c78187f53e2ace 293 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 21 273 9.6E-60 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CFK41_RS08430 0f5f35d1ec48706ce6c78187f53e2ace 293 Gene3D G3DSA:3.40.1390.30 126 257 1.7E-28 T 28-03-2018 CFK41_RS08430 0f5f35d1ec48706ce6c78187f53e2ace 293 SUPERFAMILY SSF102705 18 288 1.96E-67 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CFK41_RS08430 0f5f35d1ec48706ce6c78187f53e2ace 293 Gene3D G3DSA:3.40.1390.30 14 125 7.6E-32 T 28-03-2018 CFK41_RS00885 741ee59f85da085be58c0eff796d4720 245 Pfam PF00117 Glutamine amidotransferase class-I 51 194 5.1E-8 T 28-03-2018 IPR017926 Glutamine amidotransferase CFK41_RS00885 741ee59f85da085be58c0eff796d4720 245 SUPERFAMILY SSF52317 34 220 1.15E-23 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS00885 741ee59f85da085be58c0eff796d4720 245 Gene3D G3DSA:3.40.50.880 13 239 4.1E-21 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS16715 67d4b01b226f8acc7d61d156a52a1f51 161 Pfam PF13302 Acetyltransferase (GNAT) domain 6 144 1.0E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS16715 67d4b01b226f8acc7d61d156a52a1f51 161 SUPERFAMILY SSF55729 2 150 1.03E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS16715 67d4b01b226f8acc7d61d156a52a1f51 161 Gene3D G3DSA:3.40.630.30 1 160 2.7E-23 T 28-03-2018 CFK41_RS15490 c5449e5a8c101c83e223cc9be862dca2 156 SUPERFAMILY SSF82649 7 151 3.03E-28 T 28-03-2018 CFK41_RS15490 c5449e5a8c101c83e223cc9be862dca2 156 Gene3D G3DSA:3.90.1010.10 1 153 5.5E-40 T 28-03-2018 CFK41_RS15490 c5449e5a8c101c83e223cc9be862dca2 156 Pfam PF02657 Fe-S metabolism associated domain 23 149 4.3E-26 T 28-03-2018 IPR003808 Fe-S metabolism associated domain, SufE-like CFK41_RS00260 1fa504a7a54c175987c24b4ad0203f30 177 Gene3D G3DSA:3.40.630.30 2 171 2.4E-24 T 28-03-2018 CFK41_RS00260 1fa504a7a54c175987c24b4ad0203f30 177 Pfam PF13302 Acetyltransferase (GNAT) domain 6 141 3.7E-22 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS00260 1fa504a7a54c175987c24b4ad0203f30 177 SUPERFAMILY SSF55729 3 144 5.95E-28 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS02790 8bc82e81ba7f745e2931748ad8a71157 489 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 259 266 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CFK41_RS02790 8bc82e81ba7f745e2931748ad8a71157 489 Pfam PF00171 Aldehyde dehydrogenase family 23 481 9.3E-166 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CFK41_RS02790 8bc82e81ba7f745e2931748ad8a71157 489 SUPERFAMILY SSF53720 14 484 2.62E-166 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CFK41_RS02790 8bc82e81ba7f745e2931748ad8a71157 489 Gene3D G3DSA:3.40.309.10 278 469 2.7E-70 T 28-03-2018 CFK41_RS02790 8bc82e81ba7f745e2931748ad8a71157 489 Gene3D G3DSA:3.40.605.10 11 277 2.5E-98 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CFK41_RS08780 291b3927a8b15a9a63c93bc90e7b89af 323 Pfam PF02104 SURF1 family 25 239 2.1E-32 T 28-03-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CFK41_RS15255 06d5c090f930ac0432df4f7ffc075336 475 Pfam PF03611 PTS system sugar-specific permease component 16 400 1.0E-75 T 28-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 CFK41_RS15255 06d5c090f930ac0432df4f7ffc075336 475 PIRSF PIRSF006304 4 468 6.2E-151 T 28-03-2018 IPR013853 Galactitol permease IIC component GO:0015577|GO:0015796 CFK41_RS12125 983da5f7d29de18f428e0a6eaa3a8c5d 188 SMART SM00926 43 97 2.8E-20 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CFK41_RS12125 983da5f7d29de18f428e0a6eaa3a8c5d 188 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 45 96 3.0E-18 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CFK41_RS12125 983da5f7d29de18f428e0a6eaa3a8c5d 188 Gene3D G3DSA:3.40.50.740 99 188 3.8E-8 T 28-03-2018 CFK41_RS12125 983da5f7d29de18f428e0a6eaa3a8c5d 188 SUPERFAMILY SSF53706 44 188 6.41E-44 T 28-03-2018 CFK41_RS12125 983da5f7d29de18f428e0a6eaa3a8c5d 188 Gene3D G3DSA:2.20.25.90 44 98 1.3E-22 T 28-03-2018 CFK41_RS08825 9db81555504881cf8c9fcb0b1e13276e 498 Gene3D G3DSA:2.40.50.140 425 495 9.9E-15 T 28-03-2018 CFK41_RS08825 9db81555504881cf8c9fcb0b1e13276e 498 SMART SM00955 60 379 1.2E-46 T 28-03-2018 CFK41_RS08825 9db81555504881cf8c9fcb0b1e13276e 498 Pfam PF00773 RNB domain 64 376 9.3E-42 T 28-03-2018 CFK41_RS08825 9db81555504881cf8c9fcb0b1e13276e 498 SUPERFAMILY SSF50249 34 420 1.14E-81 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS11870 869f228936abdc85797d9f09f4d3a63e 196 Hamap MF_00048 UPF0102 protein YraN [yraN]. 82 192 20.544 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 CFK41_RS11870 869f228936abdc85797d9f09f4d3a63e 196 SUPERFAMILY SSF52980 88 182 8.31E-22 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CFK41_RS11870 869f228936abdc85797d9f09f4d3a63e 196 Gene3D G3DSA:3.40.1350.10 88 195 2.7E-32 T 28-03-2018 CFK41_RS11870 869f228936abdc85797d9f09f4d3a63e 196 Pfam PF02021 Uncharacterised protein family UPF0102 89 179 8.0E-27 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 CFK41_RS01315 48cb80a0108aa6ac8434330fc2687a88 909 Gene3D G3DSA:2.60.120.260 711 885 4.3E-7 T 28-03-2018 IPR008979 Galactose-binding domain-like CFK41_RS01315 48cb80a0108aa6ac8434330fc2687a88 909 Pfam PF17132 alpha-L-rhamnosidase 188 479 1.8E-22 T 28-03-2018 IPR033400 Alpha-L-rhamnosidase RhaM CFK41_RS01315 48cb80a0108aa6ac8434330fc2687a88 909 Pfam PF17132 alpha-L-rhamnosidase 44 148 6.3E-10 T 28-03-2018 IPR033400 Alpha-L-rhamnosidase RhaM CFK41_RS01315 48cb80a0108aa6ac8434330fc2687a88 909 Gene3D G3DSA:3.40.50.880 472 677 2.3E-9 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS01315 48cb80a0108aa6ac8434330fc2687a88 909 Gene3D G3DSA:3.20.20.150 50 358 0.0015 T 28-03-2018 CFK41_RS00485 2bcb9f1a597b52187576fb6ce9e37dcf 96 SUPERFAMILY SSF141694 2 92 4.71E-17 T 28-03-2018 CFK41_RS00485 2bcb9f1a597b52187576fb6ce9e37dcf 96 Gene3D G3DSA:2.40.30.100 3 92 1.8E-25 T 28-03-2018 IPR015018 Protein of unknown function DUF1905 CFK41_RS00485 2bcb9f1a597b52187576fb6ce9e37dcf 96 Pfam PF08922 Domain of unknown function (DUF1905) 5 91 5.7E-24 T 28-03-2018 IPR015018 Protein of unknown function DUF1905 CFK41_RS09550 5bcbec909fbc2d5a28f6e991733a8b67 181 Gene3D G3DSA:1.10.940.10 43 177 1.8E-27 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CFK41_RS09550 5bcbec909fbc2d5a28f6e991733a8b67 181 Pfam PF01029 NusB family 49 174 2.3E-20 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CFK41_RS09550 5bcbec909fbc2d5a28f6e991733a8b67 181 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 47 175 5.2E-27 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 CFK41_RS09550 5bcbec909fbc2d5a28f6e991733a8b67 181 SUPERFAMILY SSF48013 47 173 1.44E-24 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CFK41_RS16630 71d0db67a53fbfc3522540311e4fb4fd 332 Gene3D G3DSA:3.30.1180.20 186 332 6.5E-47 T 28-03-2018 CFK41_RS16630 71d0db67a53fbfc3522540311e4fb4fd 332 Gene3D G3DSA:3.40.50.10440 12 185 2.1E-63 T 28-03-2018 CFK41_RS16630 71d0db67a53fbfc3522540311e4fb4fd 332 SUPERFAMILY SSF82549 11 331 3.66E-106 T 28-03-2018 CFK41_RS16630 71d0db67a53fbfc3522540311e4fb4fd 332 Pfam PF02733 Dak1 domain 18 329 1.4E-114 T 28-03-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CFK41_RS03790 a999a4c2d7a23ee7516ea4d56ecc1a67 197 Gene3D G3DSA:2.70.40.10 1 159 9.5E-47 T 28-03-2018 CFK41_RS03790 a999a4c2d7a23ee7516ea4d56ecc1a67 197 SUPERFAMILY SSF51283 2 183 1.44E-53 T 28-03-2018 IPR029054 dUTPase-like CFK41_RS03790 a999a4c2d7a23ee7516ea4d56ecc1a67 197 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 3 181 2.0E-63 T 28-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 CFK41_RS03790 a999a4c2d7a23ee7516ea4d56ecc1a67 197 Pfam PF06559 2'-deoxycytidine 5'-triphosphate deaminase (DCD) 2 155 1.0E-11 T 28-03-2018 IPR010550 Deoxycytidine triphosphate deaminase, bacterial GO:0008829|GO:0009394 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 CFK41_RS03790 a999a4c2d7a23ee7516ea4d56ecc1a67 197 Hamap MF_00146 dCTP deaminase [dcd]. 1 182 33.979 T 28-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 CFK41_RS14005 567efeebf162122a1a1593095235a8f7 212 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 133 187 1.2E-6 T 28-03-2018 CFK41_RS14005 567efeebf162122a1a1593095235a8f7 212 Gene3D G3DSA:1.10.357.10 71 203 3.1E-18 T 28-03-2018 CFK41_RS14005 567efeebf162122a1a1593095235a8f7 212 Gene3D G3DSA:1.10.10.60 1 70 5.0E-22 T 28-03-2018 CFK41_RS14005 567efeebf162122a1a1593095235a8f7 212 SUPERFAMILY SSF46689 14 77 4.58E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CFK41_RS14005 567efeebf162122a1a1593095235a8f7 212 SUPERFAMILY SSF48498 98 197 1.5E-15 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CFK41_RS14005 567efeebf162122a1a1593095235a8f7 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 7.1E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS14005 567efeebf162122a1a1593095235a8f7 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 7.1E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS14005 567efeebf162122a1a1593095235a8f7 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 73 2.0E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CFK41_RS14150 5aca8eebbef9ce0f0f89235e6ced73e6 482 Gene3D G3DSA:3.40.309.10 243 413 3.4E-18 T 28-03-2018 CFK41_RS14150 5aca8eebbef9ce0f0f89235e6ced73e6 482 SUPERFAMILY SSF53720 7 468 4.58E-83 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CFK41_RS14150 5aca8eebbef9ce0f0f89235e6ced73e6 482 Pfam PF00171 Aldehyde dehydrogenase family 6 422 1.3E-41 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CFK41_RS14150 5aca8eebbef9ce0f0f89235e6ced73e6 482 Gene3D G3DSA:3.40.605.10 3 242 1.0E-43 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CFK41_RS14820 5b551582e2e0f43cf5db64788af9dd9f 93 Pfam PF10041 Uncharacterized conserved protein (DUF2277) 1 78 1.2E-37 T 28-03-2018 IPR018735 Protein of unknown function DUF2277 CFK41_RS03985 db53cbcf638e0eb393849fa9e2f8137b 355 Gene3D G3DSA:3.40.50.720 10 149 1.7E-14 T 28-03-2018 CFK41_RS03985 db53cbcf638e0eb393849fa9e2f8137b 355 Gene3D G3DSA:3.40.50.720 150 321 1.4E-48 T 28-03-2018 CFK41_RS03985 db53cbcf638e0eb393849fa9e2f8137b 355 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 257 273 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CFK41_RS03985 db53cbcf638e0eb393849fa9e2f8137b 355 SUPERFAMILY SSF51735 138 319 1.28E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS03985 db53cbcf638e0eb393849fa9e2f8137b 355 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 147 318 4.1E-45 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CFK41_RS14920 dd7191a41518fc8e9644b6df2d8c19ae 542 Gene3D G3DSA:3.50.50.60 2 509 7.4E-34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS14920 dd7191a41518fc8e9644b6df2d8c19ae 542 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 6 521 1.9E-162 T 28-03-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 CFK41_RS14920 dd7191a41518fc8e9644b6df2d8c19ae 542 Pfam PF01593 Flavin containing amine oxidoreductase 13 508 5.1E-31 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CFK41_RS14920 dd7191a41518fc8e9644b6df2d8c19ae 542 SUPERFAMILY SSF51905 474 508 1.45E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS14920 dd7191a41518fc8e9644b6df2d8c19ae 542 SUPERFAMILY SSF51905 1 333 1.45E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS07765 5401cc376821c5d5f0e2146b45e65590 366 Gene3D G3DSA:1.10.10.10 109 187 2.5E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS07765 5401cc376821c5d5f0e2146b45e65590 366 Pfam PF06224 Winged helix DNA-binding domain 234 352 1.1E-20 T 28-03-2018 IPR009351 Protein of unknown function DUF1006 CFK41_RS07765 5401cc376821c5d5f0e2146b45e65590 366 Pfam PF06224 Winged helix DNA-binding domain 34 203 1.1E-16 T 28-03-2018 IPR009351 Protein of unknown function DUF1006 CFK41_RS08245 7f2de1296be9554b8a209aa05d906545 422 Gene3D G3DSA:1.20.140.10 215 382 1.8E-19 T 28-03-2018 CFK41_RS08245 7f2de1296be9554b8a209aa05d906545 422 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 214 1.2E-8 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CFK41_RS08245 7f2de1296be9554b8a209aa05d906545 422 Gene3D G3DSA:1.10.540.10 7 124 1.2E-11 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CFK41_RS08245 7f2de1296be9554b8a209aa05d906545 422 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 246 381 4.3E-16 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CFK41_RS08245 7f2de1296be9554b8a209aa05d906545 422 Gene3D G3DSA:2.40.110.10 125 214 6.8E-16 T 28-03-2018 CFK41_RS08245 7f2de1296be9554b8a209aa05d906545 422 PIRSF PIRSF016578 2 394 1.4E-31 T 28-03-2018 CFK41_RS08245 7f2de1296be9554b8a209aa05d906545 422 SUPERFAMILY SSF47203 236 382 1.73E-13 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CFK41_RS08245 7f2de1296be9554b8a209aa05d906545 422 SUPERFAMILY SSF56645 23 223 2.23E-37 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CFK41_RS14210 3617575ab321fd57aeb3b9b6a6ac8d7b 477 SUPERFAMILY SSF53850 23 434 1.47E-44 T 28-03-2018 CFK41_RS14210 3617575ab321fd57aeb3b9b6a6ac8d7b 477 Gene3D G3DSA:3.40.190.10 156 459 5.0E-25 T 28-03-2018 CFK41_RS14210 3617575ab321fd57aeb3b9b6a6ac8d7b 477 Pfam PF13416 Bacterial extracellular solute-binding protein 67 375 6.0E-15 T 28-03-2018 CFK41_RS10695 31ad87a6e8c661afa2406f5b9ae0eedd 122 Pfam PF14542 GCN5-related N-acetyl-transferase 21 109 7.0E-19 T 28-03-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase CFK41_RS10695 31ad87a6e8c661afa2406f5b9ae0eedd 122 SUPERFAMILY SSF55729 12 110 6.38E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS10695 31ad87a6e8c661afa2406f5b9ae0eedd 122 Gene3D G3DSA:3.40.630.30 7 119 8.4E-20 T 28-03-2018 CFK41_RS05900 e1632c07eca8567d443364fd300c51b4 89 Pfam PF06013 Proteins of 100 residues with WXG 7 81 2.5E-8 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CFK41_RS05900 e1632c07eca8567d443364fd300c51b4 89 SUPERFAMILY SSF140453 4 85 3.66E-7 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CFK41_RS05900 e1632c07eca8567d443364fd300c51b4 89 Gene3D G3DSA:1.10.287.1060 2 89 1.8E-12 T 28-03-2018 CFK41_RS01125 8a0c6f533b4e29da788e0e8996b60a9a 360 Gene3D G3DSA:3.40.960.10 226 329 2.8E-11 T 28-03-2018 CFK41_RS08265 9e1b5e2f9c08946237e1d6b9f0f05ebb 307 Gene3D G3DSA:1.10.3470.10 7 283 2.1E-21 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CFK41_RS08265 9e1b5e2f9c08946237e1d6b9f0f05ebb 307 SUPERFAMILY SSF81345 9 269 8.24E-29 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CFK41_RS08265 9e1b5e2f9c08946237e1d6b9f0f05ebb 307 Pfam PF00950 ABC 3 transport family 12 272 1.3E-49 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CFK41_RS13485 26536ad91baab5f3cf26a052cc7126c9 178 SUPERFAMILY SSF141694 20 88 3.4E-12 T 28-03-2018 CFK41_RS13485 26536ad91baab5f3cf26a052cc7126c9 178 Pfam PF08922 Domain of unknown function (DUF1905) 21 86 5.0E-13 T 28-03-2018 IPR015018 Protein of unknown function DUF1905 CFK41_RS13485 26536ad91baab5f3cf26a052cc7126c9 178 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 94 153 9.8E-16 T 28-03-2018 CFK41_RS13485 26536ad91baab5f3cf26a052cc7126c9 178 Gene3D G3DSA:2.40.30.100 11 87 2.1E-14 T 28-03-2018 IPR015018 Protein of unknown function DUF1905 CFK41_RS08680 d4b0f8f4ed7b725f52f66f6d9930d69b 541 Pfam PF00939 Sodium:sulfate symporter transmembrane region 47 530 2.3E-88 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 CFK41_RS08680 d4b0f8f4ed7b725f52f66f6d9930d69b 541 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 224 531 5.7E-62 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 CFK41_RS07640 56aa24e81aafc63a97d37e11c894023f 124 Pfam PF13564 DoxX-like family 7 111 3.1E-23 T 28-03-2018 IPR032808 DoxX family CFK41_RS08330 03638f8a1e5ee0c2b39ab228e9d775ba 397 Pfam PF07730 Histidine kinase 203 269 1.9E-17 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CFK41_RS08330 03638f8a1e5ee0c2b39ab228e9d775ba 397 SUPERFAMILY SSF55874 272 381 9.51E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS08330 03638f8a1e5ee0c2b39ab228e9d775ba 397 Gene3D G3DSA:3.30.565.10 268 392 1.2E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS01815 f0fbf1da07294c6ecb18916cdddfdb0e 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 50 65 9.4E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS01815 f0fbf1da07294c6ecb18916cdddfdb0e 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 9.4E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS01815 f0fbf1da07294c6ecb18916cdddfdb0e 102 Pfam PF12840 Helix-turn-helix domain 15 73 1.8E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS01815 f0fbf1da07294c6ecb18916cdddfdb0e 102 SUPERFAMILY SSF46785 3 94 1.0E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS01815 f0fbf1da07294c6ecb18916cdddfdb0e 102 Gene3D G3DSA:1.10.10.10 1 89 4.2E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS01815 f0fbf1da07294c6ecb18916cdddfdb0e 102 SMART SM00418 16 94 1.8E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS13865 7f9b42fd65b426f1c05ce44c66db2d69 165 Pfam PF16571 FBP C-terminal treble-clef zinc-finger 8 162 1.6E-49 T 28-03-2018 IPR032330 Elongation factor G-binding protein, C-terminal treble-clef zinc-finger CFK41_RS06840 bd61c3bcbca4f004447994a375865385 173 SUPERFAMILY SSF50249 7 133 4.8E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CFK41_RS06840 bd61c3bcbca4f004447994a375865385 173 Pfam PF00436 Single-strand binding protein family 5 106 1.1E-18 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CFK41_RS06840 bd61c3bcbca4f004447994a375865385 173 Gene3D G3DSA:2.40.50.140 1 118 2.6E-29 T 28-03-2018 CFK41_RS01900 fdb44da4e63b6126b490075324c02c80 685 SUPERFAMILY SSF53474 424 673 3.67E-55 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS01900 fdb44da4e63b6126b490075324c02c80 685 Gene3D G3DSA:2.130.10.120 223 433 8.7E-12 T 28-03-2018 CFK41_RS01900 fdb44da4e63b6126b490075324c02c80 685 SUPERFAMILY SSF69304 42 116 2.88E-11 T 28-03-2018 CFK41_RS01900 fdb44da4e63b6126b490075324c02c80 685 SUPERFAMILY SSF69304 224 410 2.88E-11 T 28-03-2018 CFK41_RS01900 fdb44da4e63b6126b490075324c02c80 685 Pfam PF00326 Prolyl oligopeptidase family 465 673 4.4E-40 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CFK41_RS01900 fdb44da4e63b6126b490075324c02c80 685 Gene3D G3DSA:3.40.50.1820 434 683 2.2E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS01900 fdb44da4e63b6126b490075324c02c80 685 Gene3D G3DSA:2.140.10.30 4 124 0.012 T 28-03-2018 CFK41_RS00615 74b1d4604a350971b060ff55c0c29d3f 489 SUPERFAMILY SSF50969 66 270 2.04E-15 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like CFK41_RS00615 74b1d4604a350971b060ff55c0c29d3f 489 SUPERFAMILY SSF50969 308 426 2.04E-15 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like CFK41_RS00615 74b1d4604a350971b060ff55c0c29d3f 489 Gene3D G3DSA:2.130.10.10 299 452 8.4E-10 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CFK41_RS00615 74b1d4604a350971b060ff55c0c29d3f 489 Gene3D G3DSA:2.130.10.10 32 289 4.1E-7 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CFK41_RS04130 7d396124ae47033332febc743c52a79a 400 Gene3D G3DSA:1.20.1250.20 3 190 8.2E-26 T 28-03-2018 CFK41_RS04130 7d396124ae47033332febc743c52a79a 400 Pfam PF07690 Major Facilitator Superfamily 8 320 1.8E-35 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS04130 7d396124ae47033332febc743c52a79a 400 SUPERFAMILY SSF103473 4 377 3.27E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS04130 7d396124ae47033332febc743c52a79a 400 Gene3D G3DSA:1.20.1250.20 192 384 3.7E-16 T 28-03-2018 CFK41_RS16635 6e3dd37777c9586a9bf5b8bb0731e637 198 Gene3D G3DSA:2.40.50.120 34 140 7.6E-7 T 28-03-2018 CFK41_RS16635 6e3dd37777c9586a9bf5b8bb0731e637 198 SUPERFAMILY SSF50242 34 125 7.85E-5 T 28-03-2018 IPR008993 Tissue inhibitor of metalloproteinases-like, OB-fold CFK41_RS05755 63127cbf28cdc30a8f3f4f346f9b66e4 585 Gene3D G3DSA:3.10.105.10 320 539 1.9E-29 T 28-03-2018 CFK41_RS05755 63127cbf28cdc30a8f3f4f346f9b66e4 585 SUPERFAMILY SSF53850 60 539 3.98E-74 T 28-03-2018 CFK41_RS05755 63127cbf28cdc30a8f3f4f346f9b66e4 585 Gene3D G3DSA:3.90.76.10 92 184 1.3E-17 T 28-03-2018 CFK41_RS05755 63127cbf28cdc30a8f3f4f346f9b66e4 585 Gene3D G3DSA:3.40.190.10 185 319 4.2E-22 T 28-03-2018 CFK41_RS05755 63127cbf28cdc30a8f3f4f346f9b66e4 585 PIRSF PIRSF002741 9 563 4.8E-52 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CFK41_RS05755 63127cbf28cdc30a8f3f4f346f9b66e4 585 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 109 473 3.5E-50 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CFK41_RS16415 1078362fdcf6877570e22ab6f948ea4d 268 Gene3D G3DSA:1.10.3720.10 4 266 1.9E-33 T 28-03-2018 CFK41_RS16415 1078362fdcf6877570e22ab6f948ea4d 268 SUPERFAMILY SSF161098 30 252 1.07E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS16415 1078362fdcf6877570e22ab6f948ea4d 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 57 262 2.0E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01995 b78970ffde7ccf2694fb4f1694fa9e34 144 SUPERFAMILY SSF52788 6 139 2.49E-26 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CFK41_RS01995 b78970ffde7ccf2694fb4f1694fa9e34 144 SMART SM00226 8 138 1.8E-15 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CFK41_RS01995 b78970ffde7ccf2694fb4f1694fa9e34 144 Gene3D G3DSA:3.40.50.2300 4 140 3.0E-26 T 28-03-2018 CFK41_RS01995 b78970ffde7ccf2694fb4f1694fa9e34 144 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 10 136 1.0E-13 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CFK41_RS12085 85fe3c66261cc415a5b1e32897204824 449 Gene3D G3DSA:1.10.287.850 1 92 1.6E-10 T 28-03-2018 CFK41_RS08255 7c321225e5f35400b2e36e456bd415c2 177 Pfam PF09335 SNARE associated Golgi protein 16 114 8.1E-10 T 28-03-2018 IPR032816 SNARE associated Golgi protein CFK41_RS16060 5a55a02a08d680c6688228f98944409b 122 SUPERFAMILY SSF46785 7 93 1.36E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS16060 5a55a02a08d680c6688228f98944409b 122 SMART SM00418 16 95 5.9E-21 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS16060 5a55a02a08d680c6688228f98944409b 122 Pfam PF12840 Helix-turn-helix domain 16 72 2.5E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS16060 5a55a02a08d680c6688228f98944409b 122 Gene3D G3DSA:1.10.10.10 3 102 7.3E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS16060 5a55a02a08d680c6688228f98944409b 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 51 66 7.8E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS16060 5a55a02a08d680c6688228f98944409b 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 66 81 7.8E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS16060 5a55a02a08d680c6688228f98944409b 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 7.8E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CFK41_RS13935 f45643b5a9ef505c303101cd7002fec5 313 Gene3D G3DSA:3.30.200.20 5 102 4.6E-7 T 28-03-2018 CFK41_RS13935 f45643b5a9ef505c303101cd7002fec5 313 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 193 205 - T 28-03-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 CFK41_RS13935 f45643b5a9ef505c303101cd7002fec5 313 Gene3D G3DSA:3.90.1200.10 105 310 3.8E-13 T 28-03-2018 CFK41_RS13935 f45643b5a9ef505c303101cd7002fec5 313 Pfam PF01636 Phosphotransferase enzyme family 30 252 3.3E-11 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CFK41_RS13935 f45643b5a9ef505c303101cd7002fec5 313 SUPERFAMILY SSF56112 32 240 1.37E-20 T 28-03-2018 IPR011009 Protein kinase-like domain CFK41_RS14205 45e0ef16447621d90e2f28f10da7698a 287 Gene3D G3DSA:1.10.3720.10 8 275 1.0E-39 T 28-03-2018 CFK41_RS14205 45e0ef16447621d90e2f28f10da7698a 287 SUPERFAMILY SSF161098 14 282 4.21E-67 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS14205 45e0ef16447621d90e2f28f10da7698a 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 280 1.8E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS07520 90c89f1f715f6d5eff94deb6d858772a 102 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 2 102 19.416 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS07520 90c89f1f715f6d5eff94deb6d858772a 102 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 28-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CFK41_RS07520 90c89f1f715f6d5eff94deb6d858772a 102 Pfam PF00829 Ribosomal prokaryotic L21 protein 3 101 7.7E-30 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS07520 90c89f1f715f6d5eff94deb6d858772a 102 TIGRFAM TIGR00061 L21: ribosomal protein bL21 3 101 9.0E-25 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS07520 90c89f1f715f6d5eff94deb6d858772a 102 SUPERFAMILY SSF141091 2 101 4.45E-29 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS02575 d2bd24e4d00f48eaa722ff7b969f40cb 203 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 17 50 2.7E-7 T 28-03-2018 IPR023833 Signal peptide, camelysin CFK41_RS11200 e356182905383e3a885bb43ac5567273 205 Pfam PF01863 Protein of unknown function DUF45 97 165 7.0E-17 T 28-03-2018 IPR002725 Protein of unknown function DUF45 CFK41_RS11480 7cb9d5eabc8ad11883092cd8e09dd813 383 Pfam PF08478 POTRA domain, FtsQ-type 188 253 2.1E-12 T 28-03-2018 IPR013685 POTRA domain, FtsQ-type CFK41_RS10065 c1fa582b44aa91c30aaa25e90ff6e0db 213 Pfam PF11452 Protein of unknown function (DUF3000) 12 189 2.7E-61 T 28-03-2018 IPR021555 Protein of unknown function DUF3000 CFK41_RS12300 63f89b11570425290614479cbe1d1f94 251 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 19 243 4.4E-45 T 28-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CFK41_RS12300 63f89b11570425290614479cbe1d1f94 251 SUPERFAMILY SSF53448 17 241 6.72E-42 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS12300 63f89b11570425290614479cbe1d1f94 251 Gene3D G3DSA:3.90.550.10 10 246 1.0E-34 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS12300 63f89b11570425290614479cbe1d1f94 251 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 118 125 - T 28-03-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CFK41_RS09940 ba30d88cf108d8dab4b05d8152085e14 188 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 20 186 32.184 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CFK41_RS09940 ba30d88cf108d8dab4b05d8152085e14 188 Pfam PF00156 Phosphoribosyl transferase domain 61 163 1.2E-13 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CFK41_RS09940 ba30d88cf108d8dab4b05d8152085e14 188 Gene3D G3DSA:3.40.50.2020 13 187 5.3E-32 T 28-03-2018 CFK41_RS09940 ba30d88cf108d8dab4b05d8152085e14 188 SUPERFAMILY SSF53271 22 180 3.83E-41 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CFK41_RS04565 50be0e0443b7295cb5ac7ccdddc32aad 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 294 1.1E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS04565 50be0e0443b7295cb5ac7ccdddc32aad 303 SUPERFAMILY SSF161098 31 297 5.89E-69 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS04565 50be0e0443b7295cb5ac7ccdddc32aad 303 Gene3D G3DSA:1.10.3720.10 24 291 1.6E-44 T 28-03-2018 CFK41_RS13410 4b1d0b955836ccd33753143a5c630ecc 112 Gene3D G3DSA:1.10.260.40 2 86 4.3E-18 T 28-03-2018 CFK41_RS13410 4b1d0b955836ccd33753143a5c630ecc 112 SMART SM00530 15 70 1.7E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CFK41_RS13410 4b1d0b955836ccd33753143a5c630ecc 112 SUPERFAMILY SSF47413 3 72 3.76E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS13410 4b1d0b955836ccd33753143a5c630ecc 112 Pfam PF13560 Helix-turn-helix domain 12 70 5.9E-14 T 28-03-2018 CFK41_RS13870 7350bbc8a44cb3215b4708459084373e 294 Gene3D G3DSA:3.20.20.100 4 294 4.7E-75 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS13870 7350bbc8a44cb3215b4708459084373e 294 Pfam PF00248 Aldo/keto reductase family 16 293 2.2E-56 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS13870 7350bbc8a44cb3215b4708459084373e 294 SUPERFAMILY SSF51430 10 292 2.75E-74 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CFK41_RS13870 7350bbc8a44cb3215b4708459084373e 294 PRINTS PR00069 Aldo-keto reductase signature 146 163 1.5E-7 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS13870 7350bbc8a44cb3215b4708459084373e 294 PRINTS PR00069 Aldo-keto reductase signature 226 250 1.5E-7 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS13870 7350bbc8a44cb3215b4708459084373e 294 PRINTS PR00069 Aldo-keto reductase signature 183 212 1.5E-7 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS13870 7350bbc8a44cb3215b4708459084373e 294 PRINTS PR00069 Aldo-keto reductase signature 43 67 1.5E-7 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CFK41_RS07845 983fc0e606d55da9d65b6244a7b9d6ad 338 SMART SM00354 3 79 7.1E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS07845 983fc0e606d55da9d65b6244a7b9d6ad 338 SUPERFAMILY SSF53822 70 336 3.44E-52 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CFK41_RS07845 983fc0e606d55da9d65b6244a7b9d6ad 338 SUPERFAMILY SSF47413 2 65 2.06E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS07845 983fc0e606d55da9d65b6244a7b9d6ad 338 Gene3D G3DSA:1.10.260.40 4 63 3.5E-18 T 28-03-2018 CFK41_RS07845 983fc0e606d55da9d65b6244a7b9d6ad 338 Gene3D G3DSA:3.40.50.2300 178 324 8.2E-39 T 28-03-2018 CFK41_RS07845 983fc0e606d55da9d65b6244a7b9d6ad 338 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 28-03-2018 CFK41_RS07845 983fc0e606d55da9d65b6244a7b9d6ad 338 Pfam PF13377 Periplasmic binding protein-like domain 173 336 6.1E-36 T 28-03-2018 CFK41_RS07845 983fc0e606d55da9d65b6244a7b9d6ad 338 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 56 1.0E-14 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CFK41_RS07845 983fc0e606d55da9d65b6244a7b9d6ad 338 Gene3D G3DSA:3.40.50.2300 64 177 1.4E-21 T 28-03-2018 CFK41_RS10100 97e9909a1b283470cea1c348d8590d0f 350 Gene3D G3DSA:1.20.5.1000 30 79 4.1E-5 T 28-03-2018 CFK41_RS10100 97e9909a1b283470cea1c348d8590d0f 350 Pfam PF11382 Copper transport outer membrane protein, MctB 2 320 4.0E-70 T 28-03-2018 IPR021522 Copper transporter MctB GO:0006810 CFK41_RS03485 e5edae07ddbf0f6b9bb6da70d427494b 131 Pfam PF07811 TadE-like protein 15 57 1.6E-6 T 28-03-2018 IPR012495 TadE-like CFK41_RS11040 ce146bdb08258350fdb3b994f7b9a584 674 Pfam PF05649 Peptidase family M13 24 414 5.3E-84 T 28-03-2018 IPR008753 Peptidase M13, N-terminal domain GO:0006508 CFK41_RS11040 ce146bdb08258350fdb3b994f7b9a584 674 Pfam PF01431 Peptidase family M13 466 671 1.3E-73 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CFK41_RS11040 ce146bdb08258350fdb3b994f7b9a584 674 SUPERFAMILY SSF55486 11 674 8.43E-187 T 28-03-2018 CFK41_RS11040 ce146bdb08258350fdb3b994f7b9a584 674 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 497 513 1.9E-22 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CFK41_RS11040 ce146bdb08258350fdb3b994f7b9a584 674 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 458 470 1.9E-22 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CFK41_RS11040 ce146bdb08258350fdb3b994f7b9a584 674 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 476 488 1.9E-22 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CFK41_RS11040 ce146bdb08258350fdb3b994f7b9a584 674 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 571 582 1.9E-22 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CFK41_RS11040 ce146bdb08258350fdb3b994f7b9a584 674 Gene3D G3DSA:3.40.390.10 336 674 7.6E-106 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CFK41_RS11040 ce146bdb08258350fdb3b994f7b9a584 674 Gene3D G3DSA:3.40.390.10 17 194 1.1E-9 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CFK41_RS08975 27a2f558423f030f0dac00031021c186 263 Pfam PF13614 AAA domain 3 179 6.4E-30 T 28-03-2018 IPR025669 AAA domain CFK41_RS08975 27a2f558423f030f0dac00031021c186 263 SUPERFAMILY SSF52540 3 258 1.46E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS08975 27a2f558423f030f0dac00031021c186 263 Gene3D G3DSA:3.40.50.300 3 263 1.5E-47 T 28-03-2018 CFK41_RS03690 3abe443ec5a4ab6abb6501c4f84588ba 121 SMART SM00448 2 114 4.7E-39 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS03690 3abe443ec5a4ab6abb6501c4f84588ba 121 SUPERFAMILY SSF52172 1 120 4.41E-37 T 28-03-2018 IPR011006 CheY-like superfamily CFK41_RS03690 3abe443ec5a4ab6abb6501c4f84588ba 121 Pfam PF00072 Response regulator receiver domain 4 114 3.8E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CFK41_RS03690 3abe443ec5a4ab6abb6501c4f84588ba 121 Gene3D G3DSA:3.40.50.2300 1 121 9.0E-38 T 28-03-2018 CFK41_RS03055 66d10de3e7e3a21cdc866d9cf3a767cd 212 Gene3D G3DSA:3.40.630.30 11 212 2.1E-33 T 28-03-2018 CFK41_RS03055 66d10de3e7e3a21cdc866d9cf3a767cd 212 SUPERFAMILY SSF55729 21 195 1.14E-37 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS03055 66d10de3e7e3a21cdc866d9cf3a767cd 212 Pfam PF13302 Acetyltransferase (GNAT) domain 29 169 2.5E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS14280 f99e8adac61dcb1b520d41a68e8cb9ab 512 Pfam PF01547 Bacterial extracellular solute-binding protein 34 193 3.8E-13 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CFK41_RS14280 f99e8adac61dcb1b520d41a68e8cb9ab 512 SUPERFAMILY SSF53850 25 507 1.76E-53 T 28-03-2018 CFK41_RS14280 f99e8adac61dcb1b520d41a68e8cb9ab 512 Gene3D G3DSA:3.40.190.10 9 263 1.4E-26 T 28-03-2018 CFK41_RS04180 22ed6d5391bb633fbe0d842ebb84e4ec 318 SUPERFAMILY SSF161098 37 316 4.45E-50 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS04180 22ed6d5391bb633fbe0d842ebb84e4ec 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 126 303 1.4E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS04180 22ed6d5391bb633fbe0d842ebb84e4ec 318 Gene3D G3DSA:1.10.3720.10 87 313 1.3E-35 T 28-03-2018 CFK41_RS04180 22ed6d5391bb633fbe0d842ebb84e4ec 318 Gene3D G3DSA:1.20.58.370 25 69 7.3E-6 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CFK41_RS00900 8b4ea5fd53773b02351065619cf5b3d5 153 SUPERFAMILY SSF55961 14 141 4.58E-11 T 28-03-2018 CFK41_RS00900 8b4ea5fd53773b02351065619cf5b3d5 153 Gene3D G3DSA:3.30.530.20 2 150 2.9E-9 T 28-03-2018 IPR023393 START-like domain CFK41_RS15860 ca81ddae72620d0f94b4a0393754d269 460 Pfam PF02397 Bacterial sugar transferase 265 454 1.5E-67 T 28-03-2018 IPR003362 Bacterial sugar transferase CFK41_RS15860 ca81ddae72620d0f94b4a0393754d269 460 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 4 460 2.8E-126 T 28-03-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase CFK41_RS15860 ca81ddae72620d0f94b4a0393754d269 460 Gene3D G3DSA:3.40.50.720 128 256 2.0E-18 T 28-03-2018 CFK41_RS15860 ca81ddae72620d0f94b4a0393754d269 460 Pfam PF13727 CoA-binding domain 68 229 1.1E-15 T 28-03-2018 CFK41_RS12235 13e7bc725505e6164fa1a63f3447c490 392 Pfam PF03631 Virulence factor BrkB 27 278 3.4E-34 T 28-03-2018 IPR017039 Virulence factor BrkB CFK41_RS08595 666e30322c5f884090402be97db5a047 155 Pfam PF00588 SpoU rRNA Methylase family 2 142 7.1E-30 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CFK41_RS08595 666e30322c5f884090402be97db5a047 155 Gene3D G3DSA:3.40.1280.10 1 153 2.8E-36 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CFK41_RS08595 666e30322c5f884090402be97db5a047 155 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 151 30.489 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CFK41_RS08595 666e30322c5f884090402be97db5a047 155 SUPERFAMILY SSF75217 2 152 6.47E-41 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CFK41_RS08595 666e30322c5f884090402be97db5a047 155 PIRSF PIRSF029256 1 154 4.2E-55 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CFK41_RS09615 ffebcfcac2526ff2ae93025044bd44dd 265 Pfam PF01061 ABC-2 type transporter 47 230 4.3E-14 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CFK41_RS09615 ffebcfcac2526ff2ae93025044bd44dd 265 PIRSF PIRSF006648 28 68 77.0 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CFK41_RS09615 ffebcfcac2526ff2ae93025044bd44dd 265 PIRSF PIRSF006648 39 263 1.5E-17 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CFK41_RS09615 ffebcfcac2526ff2ae93025044bd44dd 265 PRINTS PR00164 ABC-2 type transport system membrane protein signature 190 209 7.7E-7 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CFK41_RS09615 ffebcfcac2526ff2ae93025044bd44dd 265 PRINTS PR00164 ABC-2 type transport system membrane protein signature 120 145 7.7E-7 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CFK41_RS09615 ffebcfcac2526ff2ae93025044bd44dd 265 PRINTS PR00164 ABC-2 type transport system membrane protein signature 154 178 7.7E-7 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CFK41_RS14460 83f9fc664729d9ef6c5be6a36ab49f31 215 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 6 183 4.0E-44 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CFK41_RS14460 83f9fc664729d9ef6c5be6a36ab49f31 215 SUPERFAMILY SSF53639 3 209 2.16E-55 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CFK41_RS14460 83f9fc664729d9ef6c5be6a36ab49f31 215 Gene3D G3DSA:3.40.225.10 2 211 2.5E-52 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CFK41_RS14460 83f9fc664729d9ef6c5be6a36ab49f31 215 SMART SM01007 5 183 5.4E-52 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CFK41_RS12390 1d34d572a71d98a24fd0be30883ca840 139 Gene3D G3DSA:3.10.180.10 3 138 9.8E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS12390 1d34d572a71d98a24fd0be30883ca840 139 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 123 3.9E-9 T 28-03-2018 CFK41_RS12390 1d34d572a71d98a24fd0be30883ca840 139 SUPERFAMILY SSF54593 1 137 1.51E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS00490 9f5213af44eaccbe27aa304e548b9a00 175 SUPERFAMILY SSF55961 23 167 3.14E-15 T 28-03-2018 CFK41_RS00490 9f5213af44eaccbe27aa304e548b9a00 175 Gene3D G3DSA:3.30.530.20 3 170 1.6E-8 T 28-03-2018 IPR023393 START-like domain CFK41_RS09465 7db78e2e2f98c4a64c2cfca9b5d011f8 155 Pfam PF10825 Protein of unknown function (DUF2752) 55 101 1.0E-16 T 28-03-2018 IPR021215 Protein of unknown function DUF2752 CFK41_RS01025 eeff4ee3cf40f58494d938126bb48e77 331 Gene3D G3DSA:2.60.40.1240 192 324 3.4E-9 T 28-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CFK41_RS02320 d3c45a2ce121325f7f158444fab03b0d 137 Gene3D G3DSA:1.20.120.580 39 136 0.0016 T 28-03-2018 IPR008201 Protein of unknown function DUF86 CFK41_RS02700 bc585869e0ec64fbb280196851ba5a50 346 PIRSF PIRSF002849 6 346 3.9E-121 T 28-03-2018 CFK41_RS02700 bc585869e0ec64fbb280196851ba5a50 346 SUPERFAMILY SSF52540 50 319 1.25E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS02700 bc585869e0ec64fbb280196851ba5a50 346 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 68 197 1.3E-61 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CFK41_RS02700 bc585869e0ec64fbb280196851ba5a50 346 Gene3D G3DSA:3.40.50.300 49 215 1.3E-24 T 28-03-2018 CFK41_RS02700 bc585869e0ec64fbb280196851ba5a50 346 Gene3D G3DSA:1.10.8.300 236 342 5.4E-31 T 28-03-2018 CFK41_RS17325 af5a14fdadf16b163cd2f0b5f0faa0e2 206 Pfam PF01810 LysE type translocator 16 201 4.3E-29 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CFK41_RS17325 af5a14fdadf16b163cd2f0b5f0faa0e2 206 PIRSF PIRSF006324 1 203 1.1E-41 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CFK41_RS10905 0b3f2e6c5b1dcc40c35d220aac76b866 272 SUPERFAMILY SSF53335 25 221 1.92E-23 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS10905 0b3f2e6c5b1dcc40c35d220aac76b866 272 Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase 120 168 2.9E-4 T 28-03-2018 IPR008471 MnmC-like methyltransferase GO:0016645|GO:0055114 CFK41_RS10905 0b3f2e6c5b1dcc40c35d220aac76b866 272 Gene3D G3DSA:3.40.50.150 12 271 3.9E-27 T 28-03-2018 CFK41_RS00315 5f7445b79cc1298d28200e64d0fedcdb 186 Gene3D G3DSA:3.40.50.300 1 181 8.8E-12 T 28-03-2018 CFK41_RS00315 5f7445b79cc1298d28200e64d0fedcdb 186 SUPERFAMILY SSF52540 2 169 5.63E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS07040 04bdced67eeea9b5a6fa0883a3c4209f 76 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 21 75 2.1E-19 T 28-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CFK41_RS07040 04bdced67eeea9b5a6fa0883a3c4209f 76 PRINTS PR00124 ATP synthase C subunit signature 51 76 2.6E-15 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07040 04bdced67eeea9b5a6fa0883a3c4209f 76 PRINTS PR00124 ATP synthase C subunit signature 34 49 2.6E-15 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07040 04bdced67eeea9b5a6fa0883a3c4209f 76 PRINTS PR00124 ATP synthase C subunit signature 13 32 2.6E-15 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07040 04bdced67eeea9b5a6fa0883a3c4209f 76 Hamap MF_01396 ATP synthase subunit c [atpH]. 11 76 15.151 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07040 04bdced67eeea9b5a6fa0883a3c4209f 76 SUPERFAMILY SSF81333 14 75 2.35E-17 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CFK41_RS07040 04bdced67eeea9b5a6fa0883a3c4209f 76 Gene3D G3DSA:1.20.20.10 12 76 3.4E-18 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CFK41_RS07040 04bdced67eeea9b5a6fa0883a3c4209f 76 ProSitePatterns PS00605 ATP synthase c subunit signature. 41 62 - T 28-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07040 04bdced67eeea9b5a6fa0883a3c4209f 76 Pfam PF00137 ATP synthase subunit C 14 74 1.2E-12 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CFK41_RS16410 47853c57f155736df83ed887c3377f48 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 282 1.6E-9 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS16410 47853c57f155736df83ed887c3377f48 290 SUPERFAMILY SSF161098 8 289 9.29E-55 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS16410 47853c57f155736df83ed887c3377f48 290 Gene3D G3DSA:1.10.3720.10 66 284 1.7E-32 T 28-03-2018 CFK41_RS00320 8477c3cc88d2bf8ba60dbb2f44597149 196 SUPERFAMILY SSF54001 20 109 9.16E-9 T 28-03-2018 CFK41_RS00320 8477c3cc88d2bf8ba60dbb2f44597149 196 Pfam PF01841 Transglutaminase-like superfamily 10 98 8.8E-6 T 28-03-2018 IPR002931 Transglutaminase-like CFK41_RS03960 53e9b8c291ee1fb1c4852ae1329db0cd 306 Gene3D G3DSA:1.10.287.850 1 94 4.4E-7 T 28-03-2018 CFK41_RS03960 53e9b8c291ee1fb1c4852ae1329db0cd 306 SUPERFAMILY SSF140453 7 86 8.63E-5 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CFK41_RS05220 8bf2fac12ddf2a84b028db90d50dfb0a 220 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 137 194 1.3E-12 T 28-03-2018 CFK41_RS02375 fb635122a31d2fb2cb8e56bdb6d930fd 326 Gene3D G3DSA:1.10.3720.10 35 320 4.6E-41 T 28-03-2018 CFK41_RS02375 fb635122a31d2fb2cb8e56bdb6d930fd 326 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 306 8.9E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS02375 fb635122a31d2fb2cb8e56bdb6d930fd 326 SUPERFAMILY SSF161098 79 307 3.66E-50 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS15940 e523cd81d7a37794500e50ea3230044b 372 Gene3D G3DSA:2.40.50.100 76 147 2.8E-4 T 28-03-2018 CFK41_RS15940 e523cd81d7a37794500e50ea3230044b 372 Gene3D G3DSA:2.40.50.100 148 351 0.006 T 28-03-2018 CFK41_RS12855 8a5ddea64ead12009fb368f2f49bf29d 290 SUPERFAMILY SSF53613 1 228 8.73E-55 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS12855 8a5ddea64ead12009fb368f2f49bf29d 290 Pfam PF08543 Phosphomethylpyrimidine kinase 14 230 6.3E-61 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CFK41_RS12855 8a5ddea64ead12009fb368f2f49bf29d 290 Gene3D G3DSA:3.40.1190.20 1 268 2.8E-44 T 28-03-2018 IPR029056 Ribokinase-like CFK41_RS05110 03b3cee8892e77b755e49baf50ed7ab3 388 Pfam PF06772 Bacterial low temperature requirement A protein (LtrA) 16 366 1.5E-84 T 28-03-2018 IPR010640 Low temperature requirement A CFK41_RS06375 d471684ab2904e98cebfa2315e59064f 296 Gene3D G3DSA:3.10.350.10 226 288 1.1E-12 T 28-03-2018 CFK41_RS12190 377d4be3e97deb38aeb6b326fd2a66dd 404 SUPERFAMILY SSF53383 14 399 2.15E-100 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CFK41_RS12190 377d4be3e97deb38aeb6b326fd2a66dd 404 Gene3D G3DSA:3.90.1150.10 306 402 2.9E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CFK41_RS12190 377d4be3e97deb38aeb6b326fd2a66dd 404 Pfam PF00155 Aminotransferase class I and II 66 394 1.3E-31 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CFK41_RS12190 377d4be3e97deb38aeb6b326fd2a66dd 404 Gene3D G3DSA:3.40.640.10 53 305 5.6E-53 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CFK41_RS03695 1fd76448ca655a08e999f9199a704ae3 491 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 39 327 7.4E-57 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS03695 1fd76448ca655a08e999f9199a704ae3 491 SUPERFAMILY SSF51445 18 334 7.9E-60 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS03695 1fd76448ca655a08e999f9199a704ae3 491 Gene3D G3DSA:3.20.20.300 16 371 1.5E-60 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CFK41_RS14120 4f56599c308cff3e85a49eafa66786d0 214 Gene3D G3DSA:3.40.430.10 4 211 6.3E-34 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CFK41_RS14120 4f56599c308cff3e85a49eafa66786d0 214 SUPERFAMILY SSF53597 59 212 3.4E-21 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CFK41_RS14120 4f56599c308cff3e85a49eafa66786d0 214 Pfam PF01872 RibD C-terminal domain 9 197 3.9E-11 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CFK41_RS14735 9d02a7c7adcf1f65c1dbfd5907e0a90b 139 SUPERFAMILY SSF103473 27 132 2.35E-5 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS14735 9d02a7c7adcf1f65c1dbfd5907e0a90b 139 Gene3D G3DSA:1.20.1250.20 34 139 7.1E-4 T 28-03-2018 CFK41_RS10675 99f412e918f2223981bdad982fd56be1 461 Pfam PF13367 Protease prsW family 163 357 3.9E-44 T 28-03-2018 IPR026898 Protease PrsW GO:0008233 CFK41_RS06720 199f87ac53280442740c7ce0c3cc2872 114 Pfam PF02583 Metal-sensitive transcriptional repressor 29 109 1.4E-30 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CFK41_RS10615 4af78167c200f2ab75e65e9508fa4e31 372 Pfam PF00501 AMP-binding enzyme 103 246 2.0E-11 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CFK41_RS10615 4af78167c200f2ab75e65e9508fa4e31 372 SUPERFAMILY SSF56801 45 362 3.14E-39 T 28-03-2018 CFK41_RS10615 4af78167c200f2ab75e65e9508fa4e31 372 Gene3D G3DSA:3.40.50.980 68 231 4.7E-19 T 28-03-2018 CFK41_RS10615 4af78167c200f2ab75e65e9508fa4e31 372 Gene3D G3DSA:3.30.300.30 279 366 4.5E-9 T 28-03-2018 CFK41_RS10615 4af78167c200f2ab75e65e9508fa4e31 372 Pfam PF13193 AMP-binding enzyme C-terminal domain 298 362 5.7E-7 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CFK41_RS06125 fec0459e31ee789d39a909290e204a50 400 SMART SM00044 157 371 2.0E-5 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CFK41_RS06125 fec0459e31ee789d39a909290e204a50 400 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 233 381 1.7E-15 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CFK41_RS06125 fec0459e31ee789d39a909290e204a50 400 SUPERFAMILY SSF55073 231 390 5.34E-35 T 28-03-2018 IPR029787 Nucleotide cyclase CFK41_RS06125 fec0459e31ee789d39a909290e204a50 400 Gene3D G3DSA:3.30.70.1230 229 396 5.6E-29 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CFK41_RS15610 81b495013cad0c0f6f0f2c7b98ff0def 180 SUPERFAMILY SSF53597 6 162 2.75E-27 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CFK41_RS15610 81b495013cad0c0f6f0f2c7b98ff0def 180 Pfam PF01872 RibD C-terminal domain 104 154 7.6E-11 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CFK41_RS15610 81b495013cad0c0f6f0f2c7b98ff0def 180 Gene3D G3DSA:3.40.430.10 6 174 5.7E-30 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CFK41_RS00540 5ef5b4301404b80632c0aeddfe0d729e 355 SUPERFAMILY SSF51679 8 335 4.97E-50 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CFK41_RS00540 5ef5b4301404b80632c0aeddfe0d729e 355 Gene3D G3DSA:3.20.20.30 3 340 1.3E-47 T 28-03-2018 CFK41_RS00540 5ef5b4301404b80632c0aeddfe0d729e 355 Pfam PF00296 Luciferase-like monooxygenase 7 257 1.3E-21 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CFK41_RS06860 2b79328d06f4f1af24fcf1a15ff9c159 209 SUPERFAMILY SSF52266 8 207 1.45E-42 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CFK41_RS06860 2b79328d06f4f1af24fcf1a15ff9c159 209 ProSitePatterns PS01098 Lipolytic enzymes "G-D-S-L" family, serine active site. 12 23 - T 28-03-2018 IPR008265 Lipase, GDSL, active site GO:0006629|GO:0016298 Reactome: R-HSA-1482788|Reactome: R-HSA-975634 CFK41_RS06860 2b79328d06f4f1af24fcf1a15ff9c159 209 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 14 198 1.1E-28 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CFK41_RS06860 2b79328d06f4f1af24fcf1a15ff9c159 209 Gene3D G3DSA:3.40.50.1110 1 208 2.7E-38 T 28-03-2018 CFK41_RS17560 00a542a768f651209e1456ae53d2e983 67 Gene3D G3DSA:2.10.110.10 1 39 2.6E-5 T 28-03-2018 CFK41_RS16950 078d84053eff77ffd405cc811fadf9c6 293 Gene3D G3DSA:3.20.20.150 2 289 2.2E-46 T 28-03-2018 CFK41_RS16950 078d84053eff77ffd405cc811fadf9c6 293 SUPERFAMILY SSF51658 5 279 4.01E-49 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS16950 078d84053eff77ffd405cc811fadf9c6 293 Pfam PF01261 Xylose isomerase-like TIM barrel 22 242 2.3E-34 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CFK41_RS01870 29a0899b88bd23024af646af941f8a1e 235 SUPERFAMILY SSF52218 6 193 4.19E-29 T 28-03-2018 IPR029039 Flavoprotein-like domain CFK41_RS01870 29a0899b88bd23024af646af941f8a1e 235 Pfam PF03358 NADPH-dependent FMN reductase 9 158 9.0E-32 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CFK41_RS01870 29a0899b88bd23024af646af941f8a1e 235 TIGRFAM TIGR04037 LLM_duo_CE1759: LLM-partnered FMN reductase, CE1759 family 11 206 3.3E-69 T 28-03-2018 IPR023932 Uncharacterised protein family, CE1759 CFK41_RS01870 29a0899b88bd23024af646af941f8a1e 235 Gene3D G3DSA:3.40.50.360 6 193 1.1E-37 T 28-03-2018 IPR029039 Flavoprotein-like domain CFK41_RS02220 b59d765653520123854ee9c7f777b0cb 305 Gene3D G3DSA:3.40.960.10 194 304 1.9E-10 T 28-03-2018 CFK41_RS09335 660279a03e7efe5484cf18084974c69a 276 PIRSF PIRSF000915 7 117 7.2E-23 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CFK41_RS09335 660279a03e7efe5484cf18084974c69a 276 PIRSF PIRSF000915 112 264 9.9E-32 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CFK41_RS09335 660279a03e7efe5484cf18084974c69a 276 Pfam PF13344 Haloacid dehalogenase-like hydrolase 13 112 3.9E-24 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CFK41_RS09335 660279a03e7efe5484cf18084974c69a 276 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 14 234 1.0E-45 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CFK41_RS09335 660279a03e7efe5484cf18084974c69a 276 Gene3D G3DSA:3.40.50.1000 2 265 7.7E-31 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS09335 660279a03e7efe5484cf18084974c69a 276 Pfam PF13242 HAD-hyrolase-like 185 257 3.4E-23 T 28-03-2018 CFK41_RS09335 660279a03e7efe5484cf18084974c69a 276 SUPERFAMILY SSF56784 12 258 6.02E-67 T 28-03-2018 IPR023214 HAD-like domain CFK41_RS03190 73984a26dfb303eb51398abcdf2bfa9a 709 Pfam PF01757 Acyltransferase family 30 379 1.5E-14 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CFK41_RS00585 eea55c5d75a21f9c3e22e6d2960d2def 252 SUPERFAMILY SSF51695 5 242 6.54E-53 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CFK41_RS00585 eea55c5d75a21f9c3e22e6d2960d2def 252 Gene3D G3DSA:3.20.20.190 2 250 3.2E-53 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CFK41_RS00585 eea55c5d75a21f9c3e22e6d2960d2def 252 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 11 239 2.0E-31 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CFK41_RS07745 caf07ca05cb8edc0dc2562fbda19f2b7 88 Pfam PF09851 Short C-terminal domain 59 84 1.3E-7 T 28-03-2018 IPR018649 SHOCT domain CFK41_RS10875 e843109eeb656c39a46cf7760318343d 235 Gene3D G3DSA:1.20.1260.10 13 127 0.0021 T 28-03-2018 IPR012347 Ferritin-related CFK41_RS10875 e843109eeb656c39a46cf7760318343d 235 SUPERFAMILY SSF48371 16 233 1.41E-48 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CFK41_RS10875 e843109eeb656c39a46cf7760318343d 235 Pfam PF08713 DNA alkylation repair enzyme 20 196 7.5E-9 T 28-03-2018 IPR014825 DNA alkylation repair enzyme CFK41_RS10390 fa77e0a16e6766443c737c0d9a1a61b1 169 SUPERFAMILY SSF55729 3 128 1.96E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS10390 fa77e0a16e6766443c737c0d9a1a61b1 169 Pfam PF00583 Acetyltransferase (GNAT) family 41 119 1.3E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS10390 fa77e0a16e6766443c737c0d9a1a61b1 169 Gene3D G3DSA:3.40.630.30 1 137 1.5E-22 T 28-03-2018 CFK41_RS06875 8e7052a9fcf20eab2af29ebc533281e1 264 Gene3D G3DSA:3.40.190.80 156 264 5.2E-22 T 28-03-2018 CFK41_RS06875 8e7052a9fcf20eab2af29ebc533281e1 264 SUPERFAMILY SSF56655 6 259 1.57E-70 T 28-03-2018 CFK41_RS06875 8e7052a9fcf20eab2af29ebc533281e1 264 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 82 95 - T 28-03-2018 IPR020583 Inositol monophosphatase, metal-binding site CFK41_RS06875 8e7052a9fcf20eab2af29ebc533281e1 264 Gene3D G3DSA:3.30.540.10 3 155 7.9E-42 T 28-03-2018 CFK41_RS06875 8e7052a9fcf20eab2af29ebc533281e1 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 82 98 1.3E-11 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CFK41_RS06875 8e7052a9fcf20eab2af29ebc533281e1 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 63 79 1.3E-11 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CFK41_RS06875 8e7052a9fcf20eab2af29ebc533281e1 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 41 61 1.3E-11 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CFK41_RS06875 8e7052a9fcf20eab2af29ebc533281e1 264 Pfam PF00459 Inositol monophosphatase family 12 260 2.0E-45 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CFK41_RS14925 e5a4a8bb95eaae3353f2022650708953 115 TIGRFAM TIGR03462 CarR_dom_SF: lycopene cyclase domain 6 95 8.3E-13 T 28-03-2018 IPR017825 Lycopene cyclase domain GO:0016872 KEGG: 00906+2.5.1.32+5.5.1.19|MetaCyc: PWY-5943|MetaCyc: PWY-5947|MetaCyc: PWY-7591 CFK41_RS02570 c0340e304faab108d2dbeaaad1b023e9 257 Gene3D G3DSA:2.60.40.200 38 212 0.0013 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CFK41_RS02570 c0340e304faab108d2dbeaaad1b023e9 257 Pfam PF07452 CHRD domain 48 176 1.7E-6 T 28-03-2018 IPR010895 CHRD CFK41_RS07580 4e06fe77063e1817b7190cb2101138bd 279 Pfam PF13560 Helix-turn-helix domain 7 85 4.2E-17 T 28-03-2018 CFK41_RS07580 4e06fe77063e1817b7190cb2101138bd 279 Gene3D G3DSA:1.10.260.40 3 87 4.1E-15 T 28-03-2018 CFK41_RS07580 4e06fe77063e1817b7190cb2101138bd 279 SUPERFAMILY SSF47413 25 80 1.01E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CFK41_RS07580 4e06fe77063e1817b7190cb2101138bd 279 SMART SM00530 10 82 4.5E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CFK41_RS01635 c259b6756ab26a5c7892b9d8210b35a7 456 SUPERFAMILY SSF53850 54 447 2.05E-41 T 28-03-2018 CFK41_RS01635 c259b6756ab26a5c7892b9d8210b35a7 456 Gene3D G3DSA:3.40.190.10 59 190 5.2E-9 T 28-03-2018 CFK41_RS01635 c259b6756ab26a5c7892b9d8210b35a7 456 Gene3D G3DSA:3.40.190.10 191 452 3.2E-22 T 28-03-2018 CFK41_RS01635 c259b6756ab26a5c7892b9d8210b35a7 456 Pfam PF13416 Bacterial extracellular solute-binding protein 99 353 2.9E-13 T 28-03-2018 CFK41_RS09645 417c1e87d99fd70a80b3e595b1558e29 390 SUPERFAMILY SSF55874 261 374 7.7E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS09645 417c1e87d99fd70a80b3e595b1558e29 390 Gene3D G3DSA:3.30.565.10 257 377 2.1E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS09645 417c1e87d99fd70a80b3e595b1558e29 390 Pfam PF07730 Histidine kinase 184 244 1.1E-13 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CFK41_RS02685 ed5a2411004f2ad4ec3c04d363bca3a5 288 SUPERFAMILY SSF56436 1 281 4.36E-87 T 28-03-2018 IPR016187 C-type lectin fold CFK41_RS02685 ed5a2411004f2ad4ec3c04d363bca3a5 288 Gene3D G3DSA:3.90.1580.10 1 288 1.7E-88 T 28-03-2018 CFK41_RS02685 ed5a2411004f2ad4ec3c04d363bca3a5 288 Pfam PF03781 Sulfatase-modifying factor enzyme 1 1 281 8.9E-77 T 28-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CFK41_RS08050 8206afaca671db0c91d1eaa414ed0187 330 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 227 4.0E-32 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CFK41_RS08050 8206afaca671db0c91d1eaa414ed0187 330 SUPERFAMILY SSF51735 5 263 5.69E-65 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS08050 8206afaca671db0c91d1eaa414ed0187 330 SUPERFAMILY SSF51735 293 328 5.69E-65 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS08050 8206afaca671db0c91d1eaa414ed0187 330 Gene3D G3DSA:3.40.50.720 3 326 8.7E-63 T 28-03-2018 CFK41_RS14325 ae7d0bec80413f3bbd2dcfba19404b44 341 Pfam PF13460 NAD(P)H-binding 7 149 3.3E-12 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS14325 ae7d0bec80413f3bbd2dcfba19404b44 341 Gene3D G3DSA:3.40.50.720 1 308 7.5E-26 T 28-03-2018 CFK41_RS14325 ae7d0bec80413f3bbd2dcfba19404b44 341 SUPERFAMILY SSF51735 1 299 7.17E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS03425 49a274f657dd221e01488073740e2f65 372 Pfam PF11228 Protein of unknown function (DUF3027) 43 238 7.0E-82 T 28-03-2018 IPR021391 Protein of unknown function DUF3027 CFK41_RS17545 07a3456bbbafedaa342bf0e28d285828 714 Gene3D G3DSA:2.60.40.1580 4 152 4.3E-10 T 28-03-2018 CFK41_RS17545 07a3456bbbafedaa342bf0e28d285828 714 Gene3D G3DSA:2.60.40.10 550 639 6.9E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS02440 c666ab6e1927b9a8896c3a5780481fbc 610 Gene3D G3DSA:1.25.40.10 210 430 8.9E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CFK41_RS02440 c666ab6e1927b9a8896c3a5780481fbc 610 SUPERFAMILY SSF48452 233 320 9.93E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CFK41_RS12510 8dad5b938b6da5904d7778e2a76a5636 358 SUPERFAMILY SSF55729 142 340 1.55E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS12510 8dad5b938b6da5904d7778e2a76a5636 358 Gene3D G3DSA:3.40.630.30 15 178 0.0031 T 28-03-2018 CFK41_RS12510 8dad5b938b6da5904d7778e2a76a5636 358 Pfam PF00583 Acetyltransferase (GNAT) family 240 333 1.6E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS12510 8dad5b938b6da5904d7778e2a76a5636 358 Gene3D G3DSA:3.40.630.30 198 356 2.3E-21 T 28-03-2018 CFK41_RS17210 2aee585f9d979ace28c978f8d9ffa96f 322 Gene3D G3DSA:1.10.10.10 64 139 5.5E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS17210 2aee585f9d979ace28c978f8d9ffa96f 322 SMART SM00895 163 299 8.4E-15 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS17210 2aee585f9d979ace28c978f8d9ffa96f 322 Pfam PF07729 FCD domain 163 298 3.9E-19 T 28-03-2018 IPR011711 GntR, C-terminal CFK41_RS17210 2aee585f9d979ace28c978f8d9ffa96f 322 SUPERFAMILY SSF48008 161 304 1.52E-17 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS17210 2aee585f9d979ace28c978f8d9ffa96f 322 Gene3D G3DSA:1.20.120.530 152 317 1.2E-17 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CFK41_RS17210 2aee585f9d979ace28c978f8d9ffa96f 322 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 97 111 5.4E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS17210 2aee585f9d979ace28c978f8d9ffa96f 322 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 111 127 5.4E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CFK41_RS17210 2aee585f9d979ace28c978f8d9ffa96f 322 SUPERFAMILY SSF46785 93 142 4.62E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS09135 46ae952a478fedd8a3ac417b1846b365 459 Pfam PF01547 Bacterial extracellular solute-binding protein 54 363 4.4E-24 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CFK41_RS09135 46ae952a478fedd8a3ac417b1846b365 459 SUPERFAMILY SSF53850 27 456 3.26E-66 T 28-03-2018 CFK41_RS09135 46ae952a478fedd8a3ac417b1846b365 459 Gene3D G3DSA:3.40.190.10 155 459 1.1E-37 T 28-03-2018 CFK41_RS14935 57710edb9a866b1641e8ec1ea369621f 294 Pfam PF01040 UbiA prenyltransferase family 28 256 1.3E-31 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CFK41_RS15400 f0ade8c8d643880ecb140883c51cd819 500 PIRSF PIRSF012666 1 496 1.4E-179 T 28-03-2018 IPR016602 Uncharacterised conserved protein UCP012666 CFK41_RS15400 f0ade8c8d643880ecb140883c51cd819 500 SUPERFAMILY SSF55931 39 458 2.75E-48 T 28-03-2018 CFK41_RS08990 99ca0db45d7f920ec180bd7b73375c0e 147 SUPERFAMILY SSF49879 32 143 1.91E-28 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 CFK41_RS08990 99ca0db45d7f920ec180bd7b73375c0e 147 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 56 141 2.5E-17 T 28-03-2018 IPR032030 YscD, cytoplasmic domain CFK41_RS08990 99ca0db45d7f920ec180bd7b73375c0e 147 SMART SM00240 70 120 3.0E-12 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CFK41_RS08990 99ca0db45d7f920ec180bd7b73375c0e 147 Gene3D G3DSA:2.60.200.20 2 147 9.1E-24 T 28-03-2018 CFK41_RS06035 bd0e6745dc611261be16ded0c760eccc 447 Pfam PF02653 Branched-chain amino acid transport system / permease component 145 425 2.8E-34 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CFK41_RS06035 bd0e6745dc611261be16ded0c760eccc 447 Gene3D G3DSA:1.10.3470.10 131 433 2.7E-43 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CFK41_RS00130 66d88d224089eeec7ae5bc9dc72d218b 136 SUPERFAMILY SSF54593 9 133 1.65E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS00130 66d88d224089eeec7ae5bc9dc72d218b 136 Gene3D G3DSA:3.10.180.10 6 136 8.4E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS00975 7c026aeb189559120801bb32cbaaf351 388 Gene3D G3DSA:1.10.287.850 1 92 1.2E-5 T 28-03-2018 CFK41_RS00975 7c026aeb189559120801bb32cbaaf351 388 ProSitePatterns PS00139 Eukaryotic thiol (cysteine) proteases cysteine active site. 164 175 - T 28-03-2018 IPR000169 Cysteine peptidase, cysteine active site CFK41_RS00975 7c026aeb189559120801bb32cbaaf351 388 Gene3D G3DSA:3.90.70.10 153 367 7.0E-6 T 28-03-2018 CFK41_RS00975 7c026aeb189559120801bb32cbaaf351 388 SUPERFAMILY SSF54001 160 352 1.45E-17 T 28-03-2018 CFK41_RS00975 7c026aeb189559120801bb32cbaaf351 388 Pfam PF00648 Calpain family cysteine protease 154 351 1.5E-9 T 28-03-2018 IPR001300 Peptidase C2, calpain, catalytic domain GO:0004198|GO:0005622|GO:0006508 Reactome: R-HSA-1474228 CFK41_RS00465 0efc202cfa811ded5ba8d27d96fb8174 418 Pfam PF04261 Dyp-type peroxidase family 73 407 2.3E-66 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CFK41_RS00465 0efc202cfa811ded5ba8d27d96fb8174 418 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 73 407 7.2E-56 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CFK41_RS00465 0efc202cfa811ded5ba8d27d96fb8174 418 SUPERFAMILY SSF54909 68 412 1.61E-72 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CFK41_RS03160 9670d3a7473ecb79873c186d1d997dba 241 Gene3D G3DSA:3.30.70.1030 14 132 2.7E-26 T 28-03-2018 CFK41_RS03160 9670d3a7473ecb79873c186d1d997dba 241 Gene3D G3DSA:3.30.70.1100 137 237 1.5E-26 T 28-03-2018 CFK41_RS03160 9670d3a7473ecb79873c186d1d997dba 241 SUPERFAMILY SSF54909 12 233 7.78E-62 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CFK41_RS03160 9670d3a7473ecb79873c186d1d997dba 241 Pfam PF06778 Chlorite dismutase 46 230 3.1E-63 T 28-03-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase CFK41_RS13040 465633f0b96057ce21bfcab7c519e191 337 SUPERFAMILY SSF161098 118 314 2.75E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS13040 465633f0b96057ce21bfcab7c519e191 337 Gene3D G3DSA:1.10.3720.10 20 320 1.6E-32 T 28-03-2018 CFK41_RS13040 465633f0b96057ce21bfcab7c519e191 337 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 142 331 1.3E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS02450 ade0f9efb96ac980db34cfd802c46905 733 Gene3D G3DSA:3.40.50.2000 374 682 5.0E-4 T 28-03-2018 CFK41_RS02450 ade0f9efb96ac980db34cfd802c46905 733 Gene3D G3DSA:3.40.50.2000 47 315 0.19 T 28-03-2018 CFK41_RS08675 4ffc9b1aeef6e001c006ce1da09a0294 689 Gene3D G3DSA:3.40.50.300 197 410 1.3E-5 T 28-03-2018 CFK41_RS08675 4ffc9b1aeef6e001c006ce1da09a0294 689 SUPERFAMILY SSF52540 209 350 4.69E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS08675 4ffc9b1aeef6e001c006ce1da09a0294 689 Hamap MF_00983 Probable primosomal protein N' [priA]. 13 688 17.529 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CFK41_RS01595 58ff9c9eb5cae830ef48cbe7c68b4e1f 393 Pfam PF02653 Branched-chain amino acid transport system / permease component 45 379 5.2E-44 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CFK41_RS01595 58ff9c9eb5cae830ef48cbe7c68b4e1f 393 Gene3D G3DSA:1.10.3470.10 205 388 2.2E-17 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CFK41_RS01595 58ff9c9eb5cae830ef48cbe7c68b4e1f 393 Gene3D G3DSA:1.10.3470.10 37 200 4.8E-10 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CFK41_RS03030 d146cda9fb36e554bc16f22b365e6d50 276 Pfam PF00144 Beta-lactamase 19 249 2.7E-28 T 28-03-2018 IPR001466 Beta-lactamase-related CFK41_RS03030 d146cda9fb36e554bc16f22b365e6d50 276 SUPERFAMILY SSF56601 19 266 9.13E-46 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CFK41_RS03030 d146cda9fb36e554bc16f22b365e6d50 276 Gene3D G3DSA:3.40.710.10 15 272 1.9E-43 T 28-03-2018 CFK41_RS13855 b2bb59387a3988e265fd5a197bc43639 1078 Gene3D G3DSA:3.40.50.300 415 817 2.2E-26 T 28-03-2018 CFK41_RS13855 b2bb59387a3988e265fd5a197bc43639 1078 SUPERFAMILY SSF52540 3 171 3.09E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS13855 b2bb59387a3988e265fd5a197bc43639 1078 SUPERFAMILY SSF52540 785 811 3.09E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS13855 b2bb59387a3988e265fd5a197bc43639 1078 SUPERFAMILY SSF52540 302 728 3.09E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS13855 b2bb59387a3988e265fd5a197bc43639 1078 Pfam PF00580 UvrD/REP helicase N-terminal domain 4 405 3.3E-47 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CFK41_RS13855 b2bb59387a3988e265fd5a197bc43639 1078 Gene3D G3DSA:3.40.50.300 2 414 1.8E-38 T 28-03-2018 CFK41_RS13855 b2bb59387a3988e265fd5a197bc43639 1078 Gene3D G3DSA:3.90.320.10 884 1054 9.6E-7 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CFK41_RS13900 d1118a57c4b1bddb914b11be08e3dee9 233 Pfam PF01774 UreD urease accessory protein 37 197 4.2E-26 T 28-03-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 CFK41_RS07645 72203030fe88a9a3e39f0b734aae092d 387 Pfam PF03594 Benzoate membrane transport protein 5 376 2.8E-90 T 28-03-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 CFK41_RS07645 72203030fe88a9a3e39f0b734aae092d 387 TIGRFAM TIGR00843 benE: benzoate transporter 5 373 2.6E-70 T 28-03-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 CFK41_RS02085 278df840fa6a5cfc723c5ef746c79772 95 PRINTS PR01217 Proline rich extensin signature 5 26 2.2E-10 T 28-03-2018 CFK41_RS02085 278df840fa6a5cfc723c5ef746c79772 95 PRINTS PR01217 Proline rich extensin signature 27 43 2.2E-10 T 28-03-2018 CFK41_RS02085 278df840fa6a5cfc723c5ef746c79772 95 PRINTS PR01217 Proline rich extensin signature 47 64 2.2E-10 T 28-03-2018 CFK41_RS02085 278df840fa6a5cfc723c5ef746c79772 95 PRINTS PR01217 Proline rich extensin signature 65 90 2.2E-10 T 28-03-2018 CFK41_RS11740 3340f732ccd3efb361a6538ea9ee27e9 376 SUPERFAMILY SSF53335 235 332 2.17E-14 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS11740 3340f732ccd3efb361a6538ea9ee27e9 376 SUPERFAMILY SSF53335 120 195 2.17E-14 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS11740 3340f732ccd3efb361a6538ea9ee27e9 376 Gene3D G3DSA:3.40.50.150 136 375 1.0E-14 T 28-03-2018 CFK41_RS11740 3340f732ccd3efb361a6538ea9ee27e9 376 Pfam PF01170 Putative RNA methylase family UPF0020 132 275 4.7E-5 T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CFK41_RS04750 0f2dc1336816924e0380f2b151963a62 346 Pfam PF14486 Domain of unknown function (DUF4432) 34 335 5.1E-10 T 28-03-2018 IPR027839 Protein of unknown function DUF4432 CFK41_RS04750 0f2dc1336816924e0380f2b151963a62 346 Gene3D G3DSA:2.70.98.10 24 342 1.8E-14 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CFK41_RS04145 f56012083debb60942d63848e7106e44 438 SUPERFAMILY SSF53623 35 284 1.83E-30 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CFK41_RS04145 f56012083debb60942d63848e7106e44 438 Pfam PF08245 Mur ligase middle domain 44 201 7.3E-20 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CFK41_RS04145 f56012083debb60942d63848e7106e44 438 Pfam PF02875 Mur ligase family, glutamate ligase domain 287 370 2.8E-22 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CFK41_RS04145 f56012083debb60942d63848e7106e44 438 Gene3D G3DSA:3.40.1190.10 35 290 3.5E-31 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CFK41_RS04145 f56012083debb60942d63848e7106e44 438 Gene3D G3DSA:3.90.190.20 291 438 1.8E-46 T 28-03-2018 CFK41_RS04145 f56012083debb60942d63848e7106e44 438 SUPERFAMILY SSF53244 287 436 6.15E-45 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CFK41_RS04145 f56012083debb60942d63848e7106e44 438 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 41 435 5.7E-82 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CFK41_RS05570 c077269ab3236123c32ef67d00411f52 126 Pfam PF04343 Protein of unknown function, DUF488 21 120 2.4E-25 T 28-03-2018 IPR007438 Protein of unknown function DUF488 CFK41_RS15150 60c7050ce6b042b0956c46d16ddc5bfa 565 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 40 464 1.6E-71 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CFK41_RS15150 60c7050ce6b042b0956c46d16ddc5bfa 565 Pfam PF00474 Sodium:solute symporter family 40 461 2.7E-47 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CFK41_RS17565 ed1f9527da11fd37b8ee8c7ee3c02827 96 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 1.9E-22 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS17565 ed1f9527da11fd37b8ee8c7ee3c02827 96 SUPERFAMILY SSF54995 1 94 4.19E-31 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS17565 ed1f9527da11fd37b8ee8c7ee3c02827 96 Pfam PF01250 Ribosomal protein S6 3 92 3.4E-27 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS17565 ed1f9527da11fd37b8ee8c7ee3c02827 96 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 20.026 T 28-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 CFK41_RS17565 ed1f9527da11fd37b8ee8c7ee3c02827 96 Gene3D G3DSA:3.30.70.60 1 96 1.4E-28 T 28-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 CFK41_RS15145 d50f87a05ae99b43e0ae3308742d6b21 444 Gene3D G3DSA:3.40.190.10 162 432 1.5E-34 T 28-03-2018 CFK41_RS15145 d50f87a05ae99b43e0ae3308742d6b21 444 Gene3D G3DSA:3.40.190.10 44 161 4.3E-13 T 28-03-2018 CFK41_RS15145 d50f87a05ae99b43e0ae3308742d6b21 444 SUPERFAMILY SSF53850 48 426 1.85E-55 T 28-03-2018 CFK41_RS15145 d50f87a05ae99b43e0ae3308742d6b21 444 Pfam PF01547 Bacterial extracellular solute-binding protein 73 338 7.0E-32 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CFK41_RS06790 cc046cbea86d42f905f3f6e0c0694ab9 221 Gene3D G3DSA:3.90.230.10 1 218 3.6E-24 T 28-03-2018 CFK41_RS06790 cc046cbea86d42f905f3f6e0c0694ab9 221 Pfam PF00557 Metallopeptidase family M24 2 210 2.4E-17 T 28-03-2018 IPR000994 Peptidase M24 CFK41_RS06790 cc046cbea86d42f905f3f6e0c0694ab9 221 SUPERFAMILY SSF55920 2 211 9.55E-23 T 28-03-2018 IPR000994 Peptidase M24 CFK41_RS15995 07bb134e1540cb3a81873fd21492eb5e 232 Gene3D G3DSA:3.40.50.720 2 203 4.8E-21 T 28-03-2018 CFK41_RS15995 07bb134e1540cb3a81873fd21492eb5e 232 SUPERFAMILY SSF51735 9 199 1.16E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS15995 07bb134e1540cb3a81873fd21492eb5e 232 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 9 97 5.0E-17 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CFK41_RS01345 d9e6998ed8a4d4dce8f263077b133a3c 553 SUPERFAMILY SSF53850 42 523 4.19E-60 T 28-03-2018 CFK41_RS01345 d9e6998ed8a4d4dce8f263077b133a3c 553 Gene3D G3DSA:3.40.190.10 118 277 1.5E-17 T 28-03-2018 CFK41_RS01345 d9e6998ed8a4d4dce8f263077b133a3c 553 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 47 430 6.3E-53 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CFK41_RS01345 d9e6998ed8a4d4dce8f263077b133a3c 553 Gene3D G3DSA:3.90.76.10 19 117 2.3E-15 T 28-03-2018 CFK41_RS01345 d9e6998ed8a4d4dce8f263077b133a3c 553 Gene3D G3DSA:3.10.105.10 278 507 5.4E-32 T 28-03-2018 CFK41_RS15700 6afcc498a4fbc525cee2d3a6b485490e 157 Pfam PF07681 DoxX 14 97 1.1E-18 T 28-03-2018 IPR032808 DoxX family CFK41_RS02380 d09a137a531f13e6182283155b5728e7 345 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 143 338 1.1E-10 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS02380 d09a137a531f13e6182283155b5728e7 345 SUPERFAMILY SSF161098 63 345 1.55E-52 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS02380 d09a137a531f13e6182283155b5728e7 345 Gene3D G3DSA:1.10.3720.10 118 339 8.5E-32 T 28-03-2018 CFK41_RS16865 76556d4ec52a5b50fdec947a5bc2e482 454 Pfam PF13416 Bacterial extracellular solute-binding protein 72 386 9.7E-29 T 28-03-2018 CFK41_RS16865 76556d4ec52a5b50fdec947a5bc2e482 454 SUPERFAMILY SSF53850 20 449 7.11E-69 T 28-03-2018 CFK41_RS16865 76556d4ec52a5b50fdec947a5bc2e482 454 Gene3D G3DSA:3.40.190.10 51 185 3.4E-20 T 28-03-2018 CFK41_RS16865 76556d4ec52a5b50fdec947a5bc2e482 454 Gene3D G3DSA:3.40.190.10 186 451 1.8E-37 T 28-03-2018 CFK41_RS14510 5a8cb43dc86a1fb15a9e62872935754b 304 Gene3D G3DSA:1.10.3720.10 16 304 1.5E-47 T 28-03-2018 CFK41_RS14510 5a8cb43dc86a1fb15a9e62872935754b 304 SUPERFAMILY SSF161098 61 291 7.46E-57 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS14510 5a8cb43dc86a1fb15a9e62872935754b 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 296 6.1E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS10980 53197633b63384efe7fd55cb22a18f8e 328 Pfam PF13460 NAD(P)H-binding 8 110 5.2E-10 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS10980 53197633b63384efe7fd55cb22a18f8e 328 Gene3D G3DSA:3.90.25.10 153 325 1.6E-5 T 28-03-2018 CFK41_RS10980 53197633b63384efe7fd55cb22a18f8e 328 SUPERFAMILY SSF51735 5 308 6.68E-23 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS10980 53197633b63384efe7fd55cb22a18f8e 328 Gene3D G3DSA:3.40.50.720 1 152 2.2E-10 T 28-03-2018 CFK41_RS02940 df3bb044a90fb7868059be6eba6f9b1a 182 Pfam PF13302 Acetyltransferase (GNAT) domain 13 137 8.8E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS02940 df3bb044a90fb7868059be6eba6f9b1a 182 SUPERFAMILY SSF55729 13 163 5.13E-16 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS02940 df3bb044a90fb7868059be6eba6f9b1a 182 Gene3D G3DSA:3.40.630.30 2 172 4.7E-18 T 28-03-2018 CFK41_RS03605 862f79e26c239cc1a6c2d950746653c7 388 SUPERFAMILY SSF161098 90 300 3.66E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS03605 862f79e26c239cc1a6c2d950746653c7 388 SUPERFAMILY SSF161098 334 375 3.66E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS03605 862f79e26c239cc1a6c2d950746653c7 388 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 81 381 3.8E-73 T 28-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 CFK41_RS03605 862f79e26c239cc1a6c2d950746653c7 388 Gene3D G3DSA:1.10.3720.10 78 388 6.7E-36 T 28-03-2018 CFK41_RS03605 862f79e26c239cc1a6c2d950746653c7 388 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 159 387 3.8E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS14115 31d19c8272fdfc9e6ac17a0a34193488 70 Gene3D G3DSA:1.10.1470.10 1 70 8.2E-16 T 28-03-2018 IPR008462 CsbD-like domain CFK41_RS14115 31d19c8272fdfc9e6ac17a0a34193488 70 Pfam PF05532 CsbD-like 5 56 3.5E-15 T 28-03-2018 IPR008462 CsbD-like domain CFK41_RS14115 31d19c8272fdfc9e6ac17a0a34193488 70 SUPERFAMILY SSF69047 4 64 1.22E-7 T 28-03-2018 IPR008462 CsbD-like domain CFK41_RS00030 3ff3a04e2aab5da3197a84a80c11e08d 454 Gene3D G3DSA:3.30.465.10 348 442 3.7E-21 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CFK41_RS00030 3ff3a04e2aab5da3197a84a80c11e08d 454 Pfam PF01595 Domain of unknown function DUF21 12 204 8.3E-33 T 28-03-2018 IPR002550 Domain of unknown function DUF21 CFK41_RS00030 3ff3a04e2aab5da3197a84a80c11e08d 454 SUPERFAMILY SSF54631 210 349 3.92E-28 T 28-03-2018 CFK41_RS00030 3ff3a04e2aab5da3197a84a80c11e08d 454 SMART SM01091 353 442 8.8E-20 T 28-03-2018 IPR005170 Transporter-associated domain CFK41_RS00030 3ff3a04e2aab5da3197a84a80c11e08d 454 SUPERFAMILY SSF56176 354 448 2.73E-16 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CFK41_RS00030 3ff3a04e2aab5da3197a84a80c11e08d 454 Pfam PF03471 Transporter associated domain 355 440 4.6E-20 T 28-03-2018 IPR005170 Transporter-associated domain CFK41_RS00030 3ff3a04e2aab5da3197a84a80c11e08d 454 Gene3D G3DSA:3.10.580.10 199 347 8.0E-31 T 28-03-2018 CFK41_RS00030 3ff3a04e2aab5da3197a84a80c11e08d 454 Pfam PF00571 CBS domain 234 271 9.0E-4 T 28-03-2018 IPR000644 CBS domain CFK41_RS00030 3ff3a04e2aab5da3197a84a80c11e08d 454 Pfam PF00571 CBS domain 294 339 0.0011 T 28-03-2018 IPR000644 CBS domain CFK41_RS10725 6a9374ac06378a4a78a96689e062b4a3 247 Gene3D G3DSA:3.40.50.880 4 245 1.7E-41 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS10725 6a9374ac06378a4a78a96689e062b4a3 247 Pfam PF07722 Peptidase C26 8 217 1.4E-47 T 28-03-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 CFK41_RS10725 6a9374ac06378a4a78a96689e062b4a3 247 SUPERFAMILY SSF52317 33 234 1.92E-32 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS12485 af0e07999753fd185b3dc54630cc988c 243 Pfam PF13529 Peptidase_C39 like family 78 213 4.4E-9 T 28-03-2018 CFK41_RS12485 af0e07999753fd185b3dc54630cc988c 243 SUPERFAMILY SSF54001 73 242 8.73E-6 T 28-03-2018 CFK41_RS12485 af0e07999753fd185b3dc54630cc988c 243 Gene3D G3DSA:3.90.70.10 82 243 1.4E-11 T 28-03-2018 CFK41_RS15275 511e250a75637c020592065f26b0b970 362 Pfam PF00676 Dehydrogenase E1 component 29 313 8.7E-80 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CFK41_RS15275 511e250a75637c020592065f26b0b970 362 SUPERFAMILY SSF52518 18 338 9.37E-92 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CFK41_RS15275 511e250a75637c020592065f26b0b970 362 Gene3D G3DSA:3.40.50.970 16 318 7.5E-79 T 28-03-2018 CFK41_RS03285 ad409c61d4c351a7f25cd913ffdbcb20 619 SUPERFAMILY SSF53756 326 563 1.24E-6 T 28-03-2018 CFK41_RS03285 ad409c61d4c351a7f25cd913ffdbcb20 619 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 379 492 5.4E-7 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 CFK41_RS17280 c8601860650ce6d3ce7489460127d837 423 SUPERFAMILY SSF55874 280 407 1.96E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS17280 c8601860650ce6d3ce7489460127d837 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 406 1.9E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS17280 c8601860650ce6d3ce7489460127d837 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 349 363 1.9E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS17280 c8601860650ce6d3ce7489460127d837 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 387 1.9E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CFK41_RS17280 c8601860650ce6d3ce7489460127d837 423 Gene3D G3DSA:3.30.565.10 277 409 4.8E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS17280 c8601860650ce6d3ce7489460127d837 423 SMART SM00387 313 409 6.5E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS17280 c8601860650ce6d3ce7489460127d837 423 Pfam PF07730 Histidine kinase 212 271 6.6E-12 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CFK41_RS17280 c8601860650ce6d3ce7489460127d837 423 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 319 407 1.4E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS17280 c8601860650ce6d3ce7489460127d837 423 PIRSF PIRSF037434 7 414 2.2E-88 T 28-03-2018 IPR017205 Signal transduction histidine kinase, ChrS CFK41_RS01450 a1c1896a91076b16615715343df19783 329 Gene3D G3DSA:1.10.3720.10 41 328 6.5E-40 T 28-03-2018 CFK41_RS01450 a1c1896a91076b16615715343df19783 329 SUPERFAMILY SSF161098 85 313 5.89E-50 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01450 a1c1896a91076b16615715343df19783 329 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 323 5.4E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS11585 31d753bbd7af6b1a8e5579f215bc0842 130 Gene3D G3DSA:3.10.350.10 70 125 4.7E-10 T 28-03-2018 CFK41_RS11585 31d753bbd7af6b1a8e5579f215bc0842 130 Pfam PF01476 LysM domain 74 123 2.4E-4 T 28-03-2018 IPR018392 LysM domain CFK41_RS15385 8f4dcfdf48cc250e140c36b30748c9a0 305 Pfam PF05675 Protein of unknown function (DUF817) 47 285 6.7E-99 T 28-03-2018 IPR008535 Protein of unknown function DUF817 CFK41_RS15385 8f4dcfdf48cc250e140c36b30748c9a0 305 PIRSF PIRSF009141 37 301 1.7E-94 T 28-03-2018 IPR008535 Protein of unknown function DUF817 CFK41_RS17420 2453ea3e0ec31ef7dd9afa85180e95c1 159 Gene3D G3DSA:3.90.960.10 1 157 7.1E-39 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CFK41_RS17420 2453ea3e0ec31ef7dd9afa85180e95c1 159 Pfam PF04073 Aminoacyl-tRNA editing domain 26 137 2.6E-27 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CFK41_RS17420 2453ea3e0ec31ef7dd9afa85180e95c1 159 SUPERFAMILY SSF55826 1 154 7.72E-34 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CFK41_RS03840 ef102f5ce8a4da131400ba882efafc99 211 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 10 189 2.6E-22 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CFK41_RS03840 ef102f5ce8a4da131400ba882efafc99 211 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 12 51 1.2E-5 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CFK41_RS03840 ef102f5ce8a4da131400ba882efafc99 211 Gene3D G3DSA:1.20.120.450 1 194 7.3E-16 T 28-03-2018 CFK41_RS03840 ef102f5ce8a4da131400ba882efafc99 211 SUPERFAMILY SSF109854 5 127 3.43E-14 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CFK41_RS04095 a48ef1d27f29261d80a097b0e0079b7b 104 Gene3D G3DSA:3.40.50.10400 10 104 1.8E-4 T 28-03-2018 IPR027269 Hypothetical PA1492 domain CFK41_RS08160 7b2d12278465417b09ac85942f2a9df1 280 Pfam PF06182 ABC-2 family transporter protein 54 277 1.8E-14 T 28-03-2018 IPR010390 Protein of unknown function DUF990 CFK41_RS12810 6024781a7452b91374f32ed00ec32c22 372 SUPERFAMILY SSF50939 17 369 8.13E-75 T 28-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CFK41_RS12810 6024781a7452b91374f32ed00ec32c22 372 Pfam PF13088 BNR repeat-like domain 43 349 5.7E-25 T 28-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CFK41_RS12810 6024781a7452b91374f32ed00ec32c22 372 Gene3D G3DSA:2.120.10.10 12 372 1.8E-62 T 28-03-2018 CFK41_RS10880 34feb44ac953eea0e2ed73b18d0005b1 191 Pfam PF13671 AAA domain 7 129 1.8E-9 T 28-03-2018 CFK41_RS10880 34feb44ac953eea0e2ed73b18d0005b1 191 Gene3D G3DSA:3.40.50.300 1 190 8.2E-17 T 28-03-2018 CFK41_RS10880 34feb44ac953eea0e2ed73b18d0005b1 191 SUPERFAMILY SSF52540 3 154 3.3E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS12205 7c633848c99207f95691dddeac6ec031 228 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS12205 7c633848c99207f95691dddeac6ec031 228 SMART SM00382 45 228 8.9E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS12205 7c633848c99207f95691dddeac6ec031 228 Pfam PF00005 ABC transporter 41 178 7.4E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS12205 7c633848c99207f95691dddeac6ec031 228 Gene3D G3DSA:3.40.50.300 8 228 4.8E-46 T 28-03-2018 CFK41_RS12205 7c633848c99207f95691dddeac6ec031 228 SUPERFAMILY SSF52540 19 226 2.72E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS06450 386738ae154901a3574de6889e7e1454 386 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 24 299 5.6E-25 T 28-03-2018 IPR017039 Virulence factor BrkB CFK41_RS06450 386738ae154901a3574de6889e7e1454 386 Pfam PF03631 Virulence factor BrkB 33 304 1.2E-45 T 28-03-2018 IPR017039 Virulence factor BrkB CFK41_RS01445 05efc95e49c22253fd4c103a3c2be484 510 Gene3D G3DSA:3.40.190.10 164 510 2.0E-33 T 28-03-2018 CFK41_RS01445 05efc95e49c22253fd4c103a3c2be484 510 SUPERFAMILY SSF53850 22 507 5.52E-71 T 28-03-2018 CFK41_RS01445 05efc95e49c22253fd4c103a3c2be484 510 Pfam PF01547 Bacterial extracellular solute-binding protein 67 365 1.2E-14 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CFK41_RS01445 05efc95e49c22253fd4c103a3c2be484 510 Gene3D G3DSA:3.40.190.10 39 163 0.16 T 28-03-2018 CFK41_RS16745 85b890d9a8359d9547d0cc8e9351199b 432 Pfam PF01757 Acyltransferase family 24 363 3.5E-19 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CFK41_RS05440 3f66374327322b7dba1f5c2e48646a99 368 Gene3D G3DSA:3.30.1330.30 263 350 5.4E-6 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CFK41_RS05440 3f66374327322b7dba1f5c2e48646a99 368 Gene3D G3DSA:3.30.420.60 118 262 9.6E-22 T 28-03-2018 CFK41_RS15970 ebb7097ffadd4f694cde0d6d7c190352 334 SUPERFAMILY SSF161098 88 317 1.31E-48 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS15970 ebb7097ffadd4f694cde0d6d7c190352 334 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 318 1.6E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS15970 ebb7097ffadd4f694cde0d6d7c190352 334 Gene3D G3DSA:1.10.3720.10 44 330 1.2E-38 T 28-03-2018 CFK41_RS03590 5a162131aff01948f9179e58bc4757e2 194 Pfam PF13828 Domain of unknown function (DUF4190) 113 176 2.6E-10 T 28-03-2018 IPR025241 Domain of unknown function DUF4190 CFK41_RS03510 29a34df30604cdae9f8d7720d560ac00 266 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 257 9.8E-21 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS03510 29a34df30604cdae9f8d7720d560ac00 266 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 264 2.8E-72 T 28-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 CFK41_RS03510 29a34df30604cdae9f8d7720d560ac00 266 Gene3D G3DSA:3.60.10.10 1 266 6.2E-45 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS03510 29a34df30604cdae9f8d7720d560ac00 266 SUPERFAMILY SSF56219 1 265 1.7E-67 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CFK41_RS16420 3fac7f6208ec25cc8b7e63ff64de44b3 392 SUPERFAMILY SSF51445 68 380 1.38E-101 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS16420 3fac7f6208ec25cc8b7e63ff64de44b3 392 Gene3D G3DSA:3.20.20.80 54 381 1.9E-65 T 28-03-2018 CFK41_RS16420 3fac7f6208ec25cc8b7e63ff64de44b3 392 SMART SM00633 104 378 8.5E-91 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CFK41_RS16420 3fac7f6208ec25cc8b7e63ff64de44b3 392 PRINTS PR00134 Glycosyl hydrolase family 10 signature 179 190 3.7E-14 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CFK41_RS16420 3fac7f6208ec25cc8b7e63ff64de44b3 392 PRINTS PR00134 Glycosyl hydrolase family 10 signature 135 147 3.7E-14 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CFK41_RS16420 3fac7f6208ec25cc8b7e63ff64de44b3 392 PRINTS PR00134 Glycosyl hydrolase family 10 signature 254 266 3.7E-14 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CFK41_RS16420 3fac7f6208ec25cc8b7e63ff64de44b3 392 PRINTS PR00134 Glycosyl hydrolase family 10 signature 225 236 3.7E-14 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CFK41_RS16420 3fac7f6208ec25cc8b7e63ff64de44b3 392 Pfam PF00331 Glycosyl hydrolase family 10 81 376 2.8E-92 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CFK41_RS13155 8844d5e05a89b67d5d45fe2df88dc043 726 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 394 712 7.4E-53 T 28-03-2018 IPR007296 Domain of unknown function DUF403 CFK41_RS13155 8844d5e05a89b67d5d45fe2df88dc043 726 Pfam PF14403 Circularly permuted ATP-grasp type 2 17 289 6.4E-63 T 28-03-2018 IPR025841 Circularly permuted ATP-grasp type 2 CFK41_RS16680 2389b12ab4630652140c0c6fac747650 135 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 24 129 7.5E-26 T 28-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 CFK41_RS16680 2389b12ab4630652140c0c6fac747650 135 Gene3D G3DSA:2.102.10.10 20 132 8.0E-18 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CFK41_RS16680 2389b12ab4630652140c0c6fac747650 135 Pfam PF13806 Rieske-like [2Fe-2S] domain 24 127 2.1E-31 T 28-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 CFK41_RS16680 2389b12ab4630652140c0c6fac747650 135 SUPERFAMILY SSF50022 24 131 4.71E-30 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CFK41_RS02360 39cfea2884bb059bc8718c3f60c774bf 143 Gene3D G3DSA:2.60.40.790 2 133 3.7E-30 T 28-03-2018 IPR008978 HSP20-like chaperone CFK41_RS02360 39cfea2884bb059bc8718c3f60c774bf 143 SUPERFAMILY SSF49764 13 131 6.63E-32 T 28-03-2018 IPR008978 HSP20-like chaperone CFK41_RS02360 39cfea2884bb059bc8718c3f60c774bf 143 Pfam PF00011 Hsp20/alpha crystallin family 35 129 5.5E-21 T 28-03-2018 IPR002068 Alpha crystallin/Hsp20 domain CFK41_RS01240 613e9e7cee64c186cb77d5ef68a6a7c8 296 SUPERFAMILY SSF161098 89 287 1.22E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01240 613e9e7cee64c186cb77d5ef68a6a7c8 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 289 6.8E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01240 613e9e7cee64c186cb77d5ef68a6a7c8 296 Gene3D G3DSA:1.10.3720.10 21 285 1.5E-43 T 28-03-2018 CFK41_RS14755 9ccf21998cbe741e4b8510ec3b5df907 436 Gene3D G3DSA:1.20.1250.20 222 420 3.1E-12 T 28-03-2018 CFK41_RS14755 9ccf21998cbe741e4b8510ec3b5df907 436 Pfam PF07690 Major Facilitator Superfamily 22 271 1.7E-17 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS14755 9ccf21998cbe741e4b8510ec3b5df907 436 SUPERFAMILY SSF103473 5 409 7.19E-39 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS14755 9ccf21998cbe741e4b8510ec3b5df907 436 Gene3D G3DSA:1.20.1250.20 6 201 2.6E-20 T 28-03-2018 CFK41_RS03005 5e1fbd792afdb18c24195aeab3fbc4a9 462 Pfam PF01098 Cell cycle protein 77 438 3.2E-77 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CFK41_RS04805 b24b50c63b0e37907811eb2978149b37 131 Pfam PF04237 YjbR 22 116 7.7E-11 T 28-03-2018 IPR007351 Uncharacterised protein YjbR CFK41_RS04805 b24b50c63b0e37907811eb2978149b37 131 SUPERFAMILY SSF142906 15 126 3.14E-11 T 28-03-2018 CFK41_RS01085 9c1680a93f61124606b985fbbdfe4c6b 222 SUPERFAMILY SSF161098 29 206 4.45E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS01085 9c1680a93f61124606b985fbbdfe4c6b 222 Gene3D G3DSA:1.10.3720.10 4 221 2.4E-25 T 28-03-2018 CFK41_RS01085 9c1680a93f61124606b985fbbdfe4c6b 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 47 218 1.0E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS02465 ebb672e610a5301248c0c4ac06efea16 374 Gene3D G3DSA:3.50.50.60 54 361 9.7E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS02465 ebb672e610a5301248c0c4ac06efea16 374 SUPERFAMILY SSF51905 255 292 2.97E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS02465 ebb672e610a5301248c0c4ac06efea16 374 SUPERFAMILY SSF51905 52 221 2.97E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS02465 ebb672e610a5301248c0c4ac06efea16 374 Pfam PF12831 FAD dependent oxidoreductase 60 234 4.0E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CFK41_RS09205 498307f044da698443e650b10cf7f369 571 Gene3D G3DSA:3.40.50.1360 321 569 1.2E-66 T 28-03-2018 CFK41_RS09205 498307f044da698443e650b10cf7f369 571 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 327 560 4.4E-60 T 28-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 CFK41_RS09205 498307f044da698443e650b10cf7f369 571 Pfam PF10128 Glucose-6-phosphate dehydrogenase subunit 52 300 2.7E-77 T 28-03-2018 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA CFK41_RS09205 498307f044da698443e650b10cf7f369 571 SUPERFAMILY SSF100950 324 568 1.33E-53 T 28-03-2018 CFK41_RS09205 498307f044da698443e650b10cf7f369 571 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 327 567 3.3E-55 T 28-03-2018 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 CFK41_RS08370 6c4b41a52148782530fcea6dbc535831 163 Pfam PF11343 Protein of unknown function (DUF3145) 5 161 7.9E-65 T 28-03-2018 IPR021491 Protein of unknown function DUF3145 CFK41_RS01970 c3121f031557dda5d19197df2b486900 136 Pfam PF03788 LrgA family 21 115 3.9E-18 T 28-03-2018 IPR005538 LrgA/CidA family GO:0016021 CFK41_RS00575 cd1fc28655605fa483cb32f4855d3e73 265 Gene3D G3DSA:1.10.3720.10 1 253 1.1E-39 T 28-03-2018 CFK41_RS00575 cd1fc28655605fa483cb32f4855d3e73 265 SUPERFAMILY SSF161098 2 265 5.79E-65 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS00575 cd1fc28655605fa483cb32f4855d3e73 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 253 1.7E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS16515 2e6df161aa967f64add9df255518393c 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 260 7.0E-63 T 28-03-2018 CFK41_RS16515 2e6df161aa967f64add9df255518393c 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 187 4.7E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS16515 2e6df161aa967f64add9df255518393c 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 93 104 4.7E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS16515 2e6df161aa967f64add9df255518393c 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 4.7E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS16515 2e6df161aa967f64add9df255518393c 262 SUPERFAMILY SSF51735 16 261 9.43E-76 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS16515 2e6df161aa967f64add9df255518393c 262 Gene3D G3DSA:3.40.50.720 59 262 3.6E-61 T 28-03-2018 CFK41_RS16515 2e6df161aa967f64add9df255518393c 262 Gene3D G3DSA:3.40.50.720 13 58 1.0E-6 T 28-03-2018 CFK41_RS16515 2e6df161aa967f64add9df255518393c 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 1.0E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS16515 2e6df161aa967f64add9df255518393c 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 1.0E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS16515 2e6df161aa967f64add9df255518393c 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 1.0E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS16515 2e6df161aa967f64add9df255518393c 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 1.0E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS16515 2e6df161aa967f64add9df255518393c 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 1.0E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS16515 2e6df161aa967f64add9df255518393c 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 1.0E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS16515 2e6df161aa967f64add9df255518393c 262 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 15 199 3.6E-4 T 28-03-2018 CFK41_RS16515 2e6df161aa967f64add9df255518393c 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 155 183 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CFK41_RS13590 2a6361220e390e286092c275afe097aa 424 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 29 403 4.5E-96 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CFK41_RS13590 2a6361220e390e286092c275afe097aa 424 Pfam PF00860 Permease family 32 384 4.9E-81 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CFK41_RS12690 874a509be14a4f44c442a0e4a03c1d97 211 Pfam PF10756 Bacterial PH domain 62 115 3.4E-5 T 28-03-2018 IPR019692 Protein of unknown function DUF2581 CFK41_RS15935 ca8a8f2b0563956ac713713140536f04 311 SUPERFAMILY SSF56601 46 308 3.33E-61 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CFK41_RS15935 ca8a8f2b0563956ac713713140536f04 311 Gene3D G3DSA:3.40.710.10 25 311 7.7E-49 T 28-03-2018 CFK41_RS15935 ca8a8f2b0563956ac713713140536f04 311 Pfam PF00144 Beta-lactamase 47 294 2.5E-34 T 28-03-2018 IPR001466 Beta-lactamase-related CFK41_RS02000 4b05fd3cf82daf1f55df45e4ead3ec6f 118 SUPERFAMILY SSF159888 6 109 9.94E-23 T 28-03-2018 CFK41_RS02000 4b05fd3cf82daf1f55df45e4ead3ec6f 118 Pfam PF08818 Domain of unknown function (DU1801) 20 108 2.2E-8 T 28-03-2018 IPR014922 Domain of unknown function DUF1801 CFK41_RS16055 57c4fdda32a63d5b295a78ebf559dfa6 120 Pfam PF00583 Acetyltransferase (GNAT) family 7 83 2.3E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS16055 57c4fdda32a63d5b295a78ebf559dfa6 120 Gene3D G3DSA:3.40.630.30 1 120 1.2E-22 T 28-03-2018 CFK41_RS16055 57c4fdda32a63d5b295a78ebf559dfa6 120 SUPERFAMILY SSF55729 5 118 6.08E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS10440 fd6d8537ad2e047c567367207f819952 260 Gene3D G3DSA:3.40.50.10420 57 229 6.0E-47 T 28-03-2018 CFK41_RS10440 fd6d8537ad2e047c567367207f819952 260 Pfam PF02589 LUD domain 124 228 2.5E-20 T 28-03-2018 IPR003741 LUD domain CFK41_RS10440 fd6d8537ad2e047c567367207f819952 260 SUPERFAMILY SSF100950 61 229 1.42E-35 T 28-03-2018 CFK41_RS02615 38adff0f5dbb241db8f46330d28435b7 382 Gene3D G3DSA:3.40.1090.10 30 257 5.6E-42 T 28-03-2018 CFK41_RS02615 38adff0f5dbb241db8f46330d28435b7 382 Pfam PF01734 Patatin-like phospholipase 46 255 1.4E-32 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CFK41_RS02615 38adff0f5dbb241db8f46330d28435b7 382 SUPERFAMILY SSF52151 40 352 1.99E-40 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CFK41_RS06310 90b221548745ed7cfcf5e989243a92a9 432 Pfam PF01882 Protein of unknown function DUF58 188 273 1.1E-18 T 28-03-2018 IPR002881 Domain of unknown function DUF58 CFK41_RS06310 90b221548745ed7cfcf5e989243a92a9 432 Gene3D G3DSA:3.40.50.410 200 408 6.6E-19 T 28-03-2018 IPR002035 von Willebrand factor, type A CFK41_RS09575 6252643081fc537d2e28604c5ba41b32 110 Pfam PF01883 Iron-sulfur cluster assembly protein 14 73 1.8E-18 T 28-03-2018 IPR002744 MIP18 family-like CFK41_RS09575 6252643081fc537d2e28604c5ba41b32 110 SUPERFAMILY SSF117916 11 104 9.48E-27 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CFK41_RS09575 6252643081fc537d2e28604c5ba41b32 110 Gene3D G3DSA:3.30.300.130 9 105 1.9E-23 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CFK41_RS15575 c5c574117def4176832a0f9528f50b94 389 Pfam PF07730 Histidine kinase 204 271 3.1E-14 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CFK41_RS15575 c5c574117def4176832a0f9528f50b94 389 Gene3D G3DSA:3.30.565.10 264 387 6.4E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS08995 f4234ecba217df71413b7cdfe0f418d6 250 Pfam PF05949 Bacterial protein of unknown function (DUF881) 112 244 1.6E-33 T 28-03-2018 IPR010273 Protein of unknown function DUF881 CFK41_RS08220 eb8050b0b279226f748b849afdada832 254 Pfam PF13489 Methyltransferase domain 14 177 2.9E-16 T 28-03-2018 CFK41_RS08220 eb8050b0b279226f748b849afdada832 254 Gene3D G3DSA:1.10.150.290 177 233 4.6E-26 T 28-03-2018 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CFK41_RS08220 eb8050b0b279226f748b849afdada832 254 SUPERFAMILY SSF53335 8 162 5.37E-32 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS08220 eb8050b0b279226f748b849afdada832 254 Gene3D G3DSA:3.40.50.150 1 176 3.0E-33 T 28-03-2018 CFK41_RS03595 e45339bd879582e5aa087cf4e48353ff 377 Gene3D G3DSA:3.40.190.10 50 192 3.9E-25 T 28-03-2018 CFK41_RS03595 e45339bd879582e5aa087cf4e48353ff 377 PIRSF PIRSF002756 7 377 3.6E-106 T 28-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CFK41_RS03595 e45339bd879582e5aa087cf4e48353ff 377 Gene3D G3DSA:3.40.190.10 193 374 3.2E-21 T 28-03-2018 CFK41_RS03595 e45339bd879582e5aa087cf4e48353ff 377 SUPERFAMILY SSF53850 53 375 8.31E-80 T 28-03-2018 CFK41_RS03595 e45339bd879582e5aa087cf4e48353ff 377 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 53 372 1.1E-61 T 28-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CFK41_RS03595 e45339bd879582e5aa087cf4e48353ff 377 Pfam PF12849 PBP superfamily domain 50 344 6.1E-46 T 28-03-2018 IPR024370 PBP domain CFK41_RS10395 f1cfb1eefb400e033191b0577eb009f6 266 Pfam PF09335 SNARE associated Golgi protein 45 170 9.2E-15 T 28-03-2018 IPR032816 SNARE associated Golgi protein CFK41_RS16765 42c4a394c850f608c706045f502e408e 287 Pfam PF02517 CAAX protease self-immunity 136 225 7.6E-11 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CFK41_RS14715 288b6209fc452c88c04cf47348accb31 348 Pfam PF04657 Putative inner membrane exporter, YdcZ 182 313 1.5E-14 T 28-03-2018 IPR006750 Putative inner membrane exporter, YdcZ CFK41_RS14715 288b6209fc452c88c04cf47348accb31 348 Pfam PF04657 Putative inner membrane exporter, YdcZ 24 168 2.7E-23 T 28-03-2018 IPR006750 Putative inner membrane exporter, YdcZ CFK41_RS08740 c161255e08df9b4e1d50fec3a384be3a 317 SMART SM00046 5 140 9.1E-4 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CFK41_RS08740 c161255e08df9b4e1d50fec3a384be3a 317 Pfam PF00781 Diacylglycerol kinase catalytic domain 6 123 1.4E-20 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CFK41_RS08740 c161255e08df9b4e1d50fec3a384be3a 317 SUPERFAMILY SSF111331 5 306 1.18E-57 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CFK41_RS08740 c161255e08df9b4e1d50fec3a384be3a 317 Gene3D G3DSA:3.40.50.10330 1 143 6.4E-23 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CFK41_RS14435 ec39941d37ab804bee8a356571e9a493 306 Gene3D G3DSA:3.20.20.140 1 302 5.2E-31 T 28-03-2018 CFK41_RS14435 ec39941d37ab804bee8a356571e9a493 306 Pfam PF04909 Amidohydrolase 10 299 1.5E-32 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CFK41_RS14435 ec39941d37ab804bee8a356571e9a493 306 SUPERFAMILY SSF51556 8 299 1.19E-42 T 28-03-2018 IPR032466 Metal-dependent hydrolase CFK41_RS14340 a83162a72755dd6a7e12e265393cead9 643 Gene3D G3DSA:1.50.10.100 34 349 3.2E-13 T 28-03-2018 CFK41_RS14340 a83162a72755dd6a7e12e265393cead9 643 Pfam PF07940 Heparinase II/III-like protein 389 543 5.3E-9 T 28-03-2018 IPR012480 Heparinase II/III-like GO:0016829 CFK41_RS14340 a83162a72755dd6a7e12e265393cead9 643 SUPERFAMILY SSF48230 180 319 3.3E-7 T 28-03-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 CFK41_RS05410 18ab7b7e2256fd6fa1ae71545ae8c4fb 280 SUPERFAMILY SSF109998 78 220 6.51E-27 T 28-03-2018 IPR027304 Trigger factor/SurA domain CFK41_RS05410 18ab7b7e2256fd6fa1ae71545ae8c4fb 280 Gene3D G3DSA:1.10.4030.10 74 204 5.5E-25 T 28-03-2018 CFK41_RS05410 18ab7b7e2256fd6fa1ae71545ae8c4fb 280 Pfam PF13624 SurA N-terminal domain 79 194 1.4E-20 T 28-03-2018 CFK41_RS00635 a226fda0a552c8c715fb3e36fbaf1759 179 Pfam PF04978 Protein of unknown function (DUF664) 28 175 1.0E-38 T 28-03-2018 IPR007061 Protein of unknown function DUF664 CFK41_RS00635 a226fda0a552c8c715fb3e36fbaf1759 179 Gene3D G3DSA:1.20.120.450 3 179 2.9E-28 T 28-03-2018 CFK41_RS00635 a226fda0a552c8c715fb3e36fbaf1759 179 SUPERFAMILY SSF109854 11 174 1.68E-37 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CFK41_RS15390 cf780542e3a69f1ff4d98a35c9651cc9 389 Pfam PF06772 Bacterial low temperature requirement A protein (LtrA) 23 375 5.2E-87 T 28-03-2018 IPR010640 Low temperature requirement A CFK41_RS02310 2171ffcaa63121883b932f6bfe280003 151 Pfam PF07553 Host cell surface-exposed lipoprotein 102 149 2.1E-23 T 28-03-2018 IPR011434 Domain of unknown function DUF1535 CFK41_RS02310 2171ffcaa63121883b932f6bfe280003 151 Pfam PF07553 Host cell surface-exposed lipoprotein 55 99 8.5E-22 T 28-03-2018 IPR011434 Domain of unknown function DUF1535 CFK41_RS14880 9d5bbf9b3aad48382a38fb507759a0f5 375 SUPERFAMILY SSF53335 157 311 1.61E-34 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS14880 9d5bbf9b3aad48382a38fb507759a0f5 375 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 262 268 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CFK41_RS14880 9d5bbf9b3aad48382a38fb507759a0f5 375 Gene3D G3DSA:3.40.50.150 159 373 1.9E-30 T 28-03-2018 CFK41_RS14880 9d5bbf9b3aad48382a38fb507759a0f5 375 Pfam PF05175 Methyltransferase small domain 165 311 1.2E-15 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CFK41_RS04105 a07e50c3336aa553136e3cfc7e848293 111 Gene3D G3DSA:3.30.530.20 15 111 5.2E-4 T 28-03-2018 IPR023393 START-like domain CFK41_RS07315 13f465ad7c3f06dc8102df9d1730bc65 176 Pfam PF10756 Bacterial PH domain 76 117 7.3E-8 T 28-03-2018 IPR019692 Protein of unknown function DUF2581 CFK41_RS08285 df6ca4b5d227deec5f64332c2acccb18 346 Pfam PF13228 Domain of unknown function (DUF4037) 133 231 4.8E-25 T 28-03-2018 IPR025117 Domain of unknown function DUF4037 CFK41_RS13645 0d64119967d6e81783b019fbb7aab5eb 621 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 76 536 9.8E-163 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CFK41_RS13645 0d64119967d6e81783b019fbb7aab5eb 621 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 38 536 1.5E-185 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CFK41_RS01895 351c88cceaf3f7e562b637cda094c6b4 189 SUPERFAMILY SSF52540 5 168 1.01E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS01895 351c88cceaf3f7e562b637cda094c6b4 189 Gene3D G3DSA:3.40.50.300 2 171 2.9E-11 T 28-03-2018 CFK41_RS10650 95bcd61d35397a4e17ea3505e0766bc9 474 SUPERFAMILY SSF53850 44 439 4.26E-58 T 28-03-2018 CFK41_RS10650 95bcd61d35397a4e17ea3505e0766bc9 474 Gene3D G3DSA:3.40.190.10 34 169 1.2E-24 T 28-03-2018 CFK41_RS10650 95bcd61d35397a4e17ea3505e0766bc9 474 Gene3D G3DSA:3.40.190.10 170 445 2.3E-26 T 28-03-2018 CFK41_RS10650 95bcd61d35397a4e17ea3505e0766bc9 474 Pfam PF13416 Bacterial extracellular solute-binding protein 56 385 5.9E-24 T 28-03-2018 CFK41_RS03810 b679d3181ee31773fce6b3fb20bd24b6 255 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 7 105 5.4E-25 T 28-03-2018 CFK41_RS02070 ff5a9d97b5dde9d05917fd32c7524501 258 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 18 218 4.2E-32 T 28-03-2018 IPR008775 Phytanoyl-CoA dioxygenase CFK41_RS02070 ff5a9d97b5dde9d05917fd32c7524501 258 SUPERFAMILY SSF51197 14 243 1.56E-50 T 28-03-2018 CFK41_RS02070 ff5a9d97b5dde9d05917fd32c7524501 258 Gene3D G3DSA:2.60.120.620 1 237 1.1E-39 T 28-03-2018 CFK41_RS02735 a3e782ca6835e855f6e50b3bcbaa0559 330 Gene3D G3DSA:1.10.3720.10 43 329 1.2E-38 T 28-03-2018 CFK41_RS02735 a3e782ca6835e855f6e50b3bcbaa0559 330 SUPERFAMILY SSF161098 87 314 1.96E-50 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS02735 a3e782ca6835e855f6e50b3bcbaa0559 330 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 325 4.4E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS04995 1e560c28b14599711f4ad8c919f519fe 257 Gene3D G3DSA:3.40.960.10 152 256 1.4E-14 T 28-03-2018 CFK41_RS04995 1e560c28b14599711f4ad8c919f519fe 257 SUPERFAMILY SSF52980 146 248 1.72E-6 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CFK41_RS04480 a7748b7974e8627d085c763e4973079c 88 Hamap MF_00422 Protein translocase subunit SecE [secE]. 27 81 11.912 T 28-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CFK41_RS04480 a7748b7974e8627d085c763e4973079c 88 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 30 83 2.1E-17 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CFK41_RS04480 a7748b7974e8627d085c763e4973079c 88 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 31 80 7.9E-17 T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CFK41_RS04480 a7748b7974e8627d085c763e4973079c 88 Gene3D G3DSA:1.20.5.1030 28 79 1.7E-18 T 28-03-2018 CFK41_RS06185 6e11da4a548441706824a82e85eac562 246 Gene3D G3DSA:3.90.550.10 2 213 5.0E-25 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS06185 6e11da4a548441706824a82e85eac562 246 SUPERFAMILY SSF53448 7 204 4.16E-29 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CFK41_RS06185 6e11da4a548441706824a82e85eac562 246 Pfam PF02348 Cytidylyltransferase 8 178 7.2E-28 T 28-03-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 CFK41_RS05780 d72b4fc184fe4a9a01fe4210a3ca0af0 277 Gene3D G3DSA:3.20.20.80 6 262 3.5E-18 T 28-03-2018 CFK41_RS05780 d72b4fc184fe4a9a01fe4210a3ca0af0 277 SUPERFAMILY SSF51445 5 250 1.33E-32 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CFK41_RS01410 4d86fd1e2413c8f869629dddf26ed291 535 Pfam PF13416 Bacterial extracellular solute-binding protein 111 401 1.5E-14 T 28-03-2018 CFK41_RS01410 4d86fd1e2413c8f869629dddf26ed291 535 SUPERFAMILY SSF53850 27 34 9.19E-57 T 28-03-2018 CFK41_RS01410 4d86fd1e2413c8f869629dddf26ed291 535 SUPERFAMILY SSF53850 86 528 9.19E-57 T 28-03-2018 CFK41_RS01410 4d86fd1e2413c8f869629dddf26ed291 535 Gene3D G3DSA:3.40.190.10 208 532 6.3E-32 T 28-03-2018 CFK41_RS15680 f8bbf89fc294c6a66a140bbb02c1f231 152 Pfam PF04341 Protein of unknown function, DUF485 59 145 1.8E-31 T 28-03-2018 IPR007436 Protein of unknown function DUF485 CFK41_RS17625 2f898ed92ff78e1c773592312770a445 182 Gene3D G3DSA:3.40.50.1010 1 158 8.3E-18 T 28-03-2018 IPR029060 PIN domain-like CFK41_RS17625 2f898ed92ff78e1c773592312770a445 182 Pfam PF01936 NYN domain 6 153 3.2E-8 T 28-03-2018 IPR021139 NYN domain, limkain-b1-type CFK41_RS02840 dbc9f771840efd9cfada142dd03bcd95 224 Pfam PF04892 VanZ like family 49 187 6.1E-18 T 28-03-2018 IPR006976 VanZ-like CFK41_RS13845 e46761c237ca5b4d32dc56752f6f6cc4 345 ProDom PD092006 MEMBRANE YWOB TRANSMEMBRANE 30 128 1.0E-9 T 28-03-2018 IPR020218 Uncharacterised protein family, YwoB, transmembrane CFK41_RS02560 64f06169942f179d1ba1898c933b8621 475 Pfam PF03929 PepSY-associated TM region 17 411 3.9E-65 T 28-03-2018 IPR005625 PepSY-associated TM protein CFK41_RS00935 05008eff13524b3cc29bcc49fca0968c 187 SUPERFAMILY SSF55729 11 166 1.14E-28 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS00935 05008eff13524b3cc29bcc49fca0968c 187 Pfam PF13302 Acetyltransferase (GNAT) domain 17 165 1.8E-18 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS00935 05008eff13524b3cc29bcc49fca0968c 187 Gene3D G3DSA:3.40.630.30 2 184 2.4E-23 T 28-03-2018 CFK41_RS11935 2b8173e6b934ff7e241f9740014b5263 308 Gene3D G3DSA:3.40.960.10 204 305 4.2E-12 T 28-03-2018 CFK41_RS11935 2b8173e6b934ff7e241f9740014b5263 308 SUPERFAMILY SSF52980 191 293 4.56E-5 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CFK41_RS12825 72ba620f1e653e7191f9fc2d18e7f397 464 Pfam PF09852 Predicted membrane protein (DUF2079) 23 387 1.4E-44 T 28-03-2018 IPR018650 Sulfolobus virus STSV1, Orf64 CFK41_RS03700 e926a11837cec0ff224281389c11947a 438 SUPERFAMILY SSF53067 66 99 3.06E-19 T 28-03-2018 CFK41_RS03700 e926a11837cec0ff224281389c11947a 438 SUPERFAMILY SSF53067 145 313 3.06E-19 T 28-03-2018 CFK41_RS03700 e926a11837cec0ff224281389c11947a 438 SUPERFAMILY SSF53067 1 33 3.06E-19 T 28-03-2018 CFK41_RS03700 e926a11837cec0ff224281389c11947a 438 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 1 373 5.3E-95 T 28-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 CFK41_RS03700 e926a11837cec0ff224281389c11947a 438 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 1 374 32.677 T 28-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 CFK41_RS03700 e926a11837cec0ff224281389c11947a 438 Gene3D G3DSA:3.30.420.40 1 183 1.2E-46 T 28-03-2018 CFK41_RS03700 e926a11837cec0ff224281389c11947a 438 Gene3D G3DSA:3.30.420.40 196 381 3.0E-15 T 28-03-2018 CFK41_RS04825 93a7f1cf35578bf823d6af506c193ff4 411 Gene3D G3DSA:3.40.50.150 210 411 4.9E-29 T 28-03-2018 CFK41_RS04825 93a7f1cf35578bf823d6af506c193ff4 411 SUPERFAMILY SSF53335 247 383 3.73E-25 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS04825 93a7f1cf35578bf823d6af506c193ff4 411 Pfam PF05175 Methyltransferase small domain 227 407 1.8E-38 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CFK41_RS04825 93a7f1cf35578bf823d6af506c193ff4 411 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 340 346 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CFK41_RS05295 2dd56f46e759c88ef8229d15d20c3c5c 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 272 4.1E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS05295 2dd56f46e759c88ef8229d15d20c3c5c 297 Gene3D G3DSA:1.10.3720.10 19 277 4.7E-33 T 28-03-2018 CFK41_RS05295 2dd56f46e759c88ef8229d15d20c3c5c 297 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 67 167 3.2E-16 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CFK41_RS05295 2dd56f46e759c88ef8229d15d20c3c5c 297 SUPERFAMILY SSF161098 64 258 9.55E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS09695 03be22463080a514e6f8f92c1436e3f1 100 Pfam PF13834 Domain of unknown function (DUF4193) 1 98 3.6E-42 T 28-03-2018 IPR025242 Protein of unknown function DUF4193 CFK41_RS16670 0532fc75d60f6e9ac9556dbc086f2def 293 SUPERFAMILY SSF69618 21 283 9.55E-48 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CFK41_RS16670 0532fc75d60f6e9ac9556dbc086f2def 293 Gene3D G3DSA:3.40.50.10090 56 179 2.2E-20 T 28-03-2018 CFK41_RS16670 0532fc75d60f6e9ac9556dbc086f2def 293 Pfam PF02602 Uroporphyrinogen-III synthase HemD 33 275 8.3E-38 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CFK41_RS16670 0532fc75d60f6e9ac9556dbc086f2def 293 Gene3D G3DSA:3.40.50.10090 180 285 2.5E-14 T 28-03-2018 CFK41_RS15590 63393dd57b1e70b719657f8d8e0b2660 280 SUPERFAMILY SSF161098 78 266 4.97E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS15590 63393dd57b1e70b719657f8d8e0b2660 280 Gene3D G3DSA:1.10.3720.10 33 279 2.6E-23 T 28-03-2018 CFK41_RS15590 63393dd57b1e70b719657f8d8e0b2660 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 276 1.1E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS09375 ed4e59cc23680a92f6752e5acd22e8f8 162 SUPERFAMILY SSF53850 10 126 9.87E-11 T 28-03-2018 CFK41_RS09375 ed4e59cc23680a92f6752e5acd22e8f8 162 Gene3D G3DSA:3.40.190.10 33 159 1.6E-10 T 28-03-2018 CFK41_RS01220 ab33d9d482f7b58f36e632dc463583cd 255 Pfam PF03746 LamB/YcsF family 9 245 9.2E-92 T 28-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CFK41_RS01220 ab33d9d482f7b58f36e632dc463583cd 255 Gene3D G3DSA:3.20.20.370 7 253 1.4E-96 T 28-03-2018 CFK41_RS01220 ab33d9d482f7b58f36e632dc463583cd 255 SUPERFAMILY SSF88713 8 251 9.64E-85 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CFK41_RS08485 80fcb91bca09222bc684c86c76f6217a 305 Pfam PF12705 PD-(D/E)XK nuclease superfamily 89 205 7.7E-5 T 28-03-2018 CFK41_RS13950 dbc3c14de240c9e9fb69b5218f090ce5 374 Pfam PF11175 Protein of unknown function (DUF2961) 87 338 1.9E-79 T 28-03-2018 IPR021345 Protein of unknown function DUF2961 CFK41_RS16760 77ff71d218a1b86f939cdc60b5ecc914 224 Pfam PF13649 Methyltransferase domain 62 154 3.5E-15 T 28-03-2018 CFK41_RS16760 77ff71d218a1b86f939cdc60b5ecc914 224 Gene3D G3DSA:3.40.50.150 2 219 1.0E-26 T 28-03-2018 CFK41_RS16760 77ff71d218a1b86f939cdc60b5ecc914 224 SUPERFAMILY SSF53335 25 216 3.01E-31 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS16235 41db6d9ae2763f43f7ef4460daacbf05 317 SUPERFAMILY SSF51735 3 153 3.29E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS16235 41db6d9ae2763f43f7ef4460daacbf05 317 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 17 122 7.8E-18 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CFK41_RS16235 41db6d9ae2763f43f7ef4460daacbf05 317 SUPERFAMILY SSF55347 132 286 2.45E-27 T 28-03-2018 CFK41_RS16235 41db6d9ae2763f43f7ef4460daacbf05 317 Gene3D G3DSA:3.40.50.720 1 136 4.9E-29 T 28-03-2018 CFK41_RS16235 41db6d9ae2763f43f7ef4460daacbf05 317 Gene3D G3DSA:3.30.360.10 137 317 7.1E-33 T 28-03-2018 CFK41_RS16235 41db6d9ae2763f43f7ef4460daacbf05 317 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 136 236 2.7E-5 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CFK41_RS04880 b9573f1632052df89cd9da431fca573b 147 Pfam PF00572 Ribosomal protein L13 15 137 5.5E-56 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CFK41_RS04880 b9573f1632052df89cd9da431fca573b 147 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 5 140 3.4E-60 T 28-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CFK41_RS04880 b9573f1632052df89cd9da431fca573b 147 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 143 28.577 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CFK41_RS04880 b9573f1632052df89cd9da431fca573b 147 Gene3D G3DSA:3.90.1180.10 1 147 7.7E-61 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CFK41_RS04880 b9573f1632052df89cd9da431fca573b 147 SUPERFAMILY SSF52161 5 144 1.16E-57 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CFK41_RS04880 b9573f1632052df89cd9da431fca573b 147 PIRSF PIRSF002181 2 146 2.5E-45 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CFK41_RS17050 31293355e1680e7640b7a2155ea2e2ac 144 Gene3D G3DSA:1.20.5.110 48 107 0.004 T 28-03-2018 CFK41_RS17540 9353084eb1d26625a8b8b0f6e9de9366 579 Pfam PF03023 MviN-like protein 59 517 3.4E-63 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CFK41_RS17540 9353084eb1d26625a8b8b0f6e9de9366 579 PRINTS PR01806 Virulence factor MviN signature 400 419 4.3E-12 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CFK41_RS17540 9353084eb1d26625a8b8b0f6e9de9366 579 PRINTS PR01806 Virulence factor MviN signature 57 76 4.3E-12 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CFK41_RS17540 9353084eb1d26625a8b8b0f6e9de9366 579 PRINTS PR01806 Virulence factor MviN signature 304 330 4.3E-12 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CFK41_RS17540 9353084eb1d26625a8b8b0f6e9de9366 579 PRINTS PR01806 Virulence factor MviN signature 177 198 4.3E-12 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CFK41_RS17540 9353084eb1d26625a8b8b0f6e9de9366 579 PRINTS PR01806 Virulence factor MviN signature 153 177 4.3E-12 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CFK41_RS09870 2935e1f9ad103d4700c5163c35a15f98 138 Pfam PF12270 Cytochrome c oxidase subunit IV 1 137 1.6E-35 T 28-03-2018 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CFK41_RS09870 2935e1f9ad103d4700c5163c35a15f98 138 PIRSF PIRSF017385 1 138 5.6E-34 T 28-03-2018 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CFK41_RS03100 191ebd26a0e6af430934e4d78a101e1b 118 Gene3D G3DSA:3.10.180.10 1 112 4.2E-14 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS03100 191ebd26a0e6af430934e4d78a101e1b 118 SUPERFAMILY SSF54593 3 102 9.8E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS07920 44e51d74bf7a04f3de8c7819fcc40790 175 Pfam PF14279 HNH endonuclease 89 148 6.9E-13 T 28-03-2018 IPR029471 HNH endonuclease 5 CFK41_RS07920 44e51d74bf7a04f3de8c7819fcc40790 175 SMART SM00507 76 135 2.3E-9 T 28-03-2018 IPR003615 HNH nuclease CFK41_RS07920 44e51d74bf7a04f3de8c7819fcc40790 175 Gene3D G3DSA:3.40.1800.10 76 151 6.4E-17 T 28-03-2018 CFK41_RS04175 f27c18e1c01fa8e7d6f26b5f38c41cb8 308 SUPERFAMILY SSF161098 40 308 5.51E-59 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS04175 f27c18e1c01fa8e7d6f26b5f38c41cb8 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 301 4.0E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS04175 f27c18e1c01fa8e7d6f26b5f38c41cb8 308 Gene3D G3DSA:1.10.3720.10 30 296 2.5E-36 T 28-03-2018 CFK41_RS04385 e78426944a8bbf3a4f63d04140b5da7c 174 Gene3D G3DSA:3.40.630.30 1 165 6.3E-25 T 28-03-2018 CFK41_RS04385 e78426944a8bbf3a4f63d04140b5da7c 174 SUPERFAMILY SSF55729 1 160 1.16E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS04385 e78426944a8bbf3a4f63d04140b5da7c 174 Pfam PF13302 Acetyltransferase (GNAT) domain 1 134 2.2E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS01460 765b02468ec5190b0f55c9519f584933 691 SUPERFAMILY SSF69318 174 429 7.98E-12 T 28-03-2018 CFK41_RS01460 765b02468ec5190b0f55c9519f584933 691 SUPERFAMILY SSF69318 591 624 7.98E-12 T 28-03-2018 CFK41_RS01460 765b02468ec5190b0f55c9519f584933 691 Gene3D G3DSA:2.130.10.130 132 282 1.7E-6 T 28-03-2018 CFK41_RS01460 765b02468ec5190b0f55c9519f584933 691 Gene3D G3DSA:2.130.10.130 339 627 0.0017 T 28-03-2018 CFK41_RS01460 765b02468ec5190b0f55c9519f584933 691 Gene3D G3DSA:2.60.40.10 59 131 2.9E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold CFK41_RS15310 d1c1222dca7af420dfeabde87c3dfab6 207 Pfam PF06197 Protein of unknown function (DUF998) 9 202 2.3E-10 T 28-03-2018 IPR009339 Protein of unknown function DUF998 CFK41_RS12710 3415d32435ff87c892cf85a3d2581199 256 Pfam PF13559 Domain of unknown function (DUF4129) 171 239 3.1E-11 T 28-03-2018 IPR025403 Domain of unknown function DUF4129 CFK41_RS11650 be797b8d13760d61d25859d33cb1e4d6 166 SUPERFAMILY SSF142433 16 164 6.28E-44 T 28-03-2018 IPR008136 CinA, C-terminal CFK41_RS11650 be797b8d13760d61d25859d33cb1e4d6 166 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 17 163 5.3E-32 T 28-03-2018 IPR008136 CinA, C-terminal CFK41_RS11650 be797b8d13760d61d25859d33cb1e4d6 166 Gene3D G3DSA:3.90.950.20 13 166 4.5E-49 T 28-03-2018 CFK41_RS11650 be797b8d13760d61d25859d33cb1e4d6 166 Pfam PF02464 Competence-damaged protein 16 162 2.9E-45 T 28-03-2018 IPR008136 CinA, C-terminal CFK41_RS09370 eb3ca7bb80da3f345800e203c43ae379 334 SUPERFAMILY SSF161111 36 239 3.92E-24 T 28-03-2018 CFK41_RS09370 eb3ca7bb80da3f345800e203c43ae379 334 Gene3D G3DSA:1.20.1510.10 29 237 3.9E-18 T 28-03-2018 CFK41_RS09370 eb3ca7bb80da3f345800e203c43ae379 334 Pfam PF01545 Cation efflux family 39 235 1.6E-13 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CFK41_RS07795 55b0032bfeacde6527634798daff5b20 316 SUPERFAMILY SSF161098 75 303 2.62E-64 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS07795 55b0032bfeacde6527634798daff5b20 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 305 4.7E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS07795 55b0032bfeacde6527634798daff5b20 316 Gene3D G3DSA:1.10.3720.10 30 316 6.0E-55 T 28-03-2018 CFK41_RS14795 12de1934967b8e815c7e2236d14476f7 360 Pfam PF04143 Sulphur transport 18 333 6.5E-91 T 28-03-2018 IPR007272 Sulphur transport domain CFK41_RS04230 4c21f974e4d696cb227eda1ea4b73015 491 SUPERFAMILY SSF52091 400 478 9.42E-10 T 28-03-2018 IPR002645 STAS domain CFK41_RS04230 4c21f974e4d696cb227eda1ea4b73015 491 Pfam PF00916 Sulfate permease family 159 365 7.3E-27 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CFK41_RS04230 4c21f974e4d696cb227eda1ea4b73015 491 Pfam PF00916 Sulfate permease family 23 153 7.7E-17 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CFK41_RS04230 4c21f974e4d696cb227eda1ea4b73015 491 Pfam PF01740 STAS domain 411 478 6.3E-6 T 28-03-2018 IPR002645 STAS domain CFK41_RS04230 4c21f974e4d696cb227eda1ea4b73015 491 Gene3D G3DSA:3.30.750.24 396 482 1.9E-12 T 28-03-2018 IPR002645 STAS domain CFK41_RS15735 48dbec107446387adefa28d77f25890d 262 SUPERFAMILY SSF47240 17 213 5.0E-21 T 28-03-2018 IPR009078 Ferritin-like superfamily CFK41_RS15735 48dbec107446387adefa28d77f25890d 262 Gene3D G3DSA:1.10.620.20 9 237 7.5E-32 T 28-03-2018 CFK41_RS05275 2ec5c0e9c8b513bf176f1bdb70b0713c 79 Pfam PF04024 PspC domain 13 65 9.1E-12 T 28-03-2018 IPR007168 Phage shock protein, PspC, N-terminal CFK41_RS17410 4e1ceda727e5f855bc9fcf8bdecdf23e 271 Gene3D G3DSA:3.10.490.10 78 217 3.4E-4 T 28-03-2018 CFK41_RS13395 e80af21982de8a90471190d340c62005 163 Pfam PF11188 Protein of unknown function (DUF2975) 46 160 8.5E-18 T 28-03-2018 IPR021354 Protein of unknown function DUF2975 CFK41_RS16210 57816375f4e2f8dc73d75ece6e0c2a3a 236 Pfam PF01323 DSBA-like thioredoxin domain 18 222 6.5E-34 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CFK41_RS16210 57816375f4e2f8dc73d75ece6e0c2a3a 236 Gene3D G3DSA:3.40.30.10 16 235 3.4E-43 T 28-03-2018 CFK41_RS16210 57816375f4e2f8dc73d75ece6e0c2a3a 236 SUPERFAMILY SSF52833 17 228 2.44E-32 T 28-03-2018 IPR012336 Thioredoxin-like fold CFK41_RS08115 d478cac323b41831ccb87287b951896f 250 Pfam PF03473 MOSC domain 63 175 1.9E-21 T 28-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 CFK41_RS08115 d478cac323b41831ccb87287b951896f 250 Gene3D G3DSA:2.40.33.20 10 240 1.9E-41 T 28-03-2018 CFK41_RS08115 d478cac323b41831ccb87287b951896f 250 SUPERFAMILY SSF50800 16 206 1.1E-49 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain CFK41_RS11170 677a3cff963eafa6c8f4a24b975cd219 514 Gene3D G3DSA:1.10.1740.10 27 111 1.5E-4 T 28-03-2018 CFK41_RS00830 105764ba005e003e34fceee88362e12d 477 Pfam PF16980 Putative citrate transport 3 428 7.0E-137 T 28-03-2018 IPR031566 Putative citrate transporter CFK41_RS16435 7a2901f0ca4b6f45dd53b07df6df9c54 557 Pfam PF13416 Bacterial extracellular solute-binding protein 90 412 1.8E-18 T 28-03-2018 CFK41_RS16435 7a2901f0ca4b6f45dd53b07df6df9c54 557 SUPERFAMILY SSF53850 32 552 4.8E-72 T 28-03-2018 CFK41_RS16435 7a2901f0ca4b6f45dd53b07df6df9c54 557 Gene3D G3DSA:3.40.190.10 190 554 2.2E-37 T 28-03-2018 CFK41_RS07510 5027423f4ce5e08a72b8f30fcae7b891 518 PIRSF PIRSF006446 1 513 3.2E-120 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CFK41_RS07510 5027423f4ce5e08a72b8f30fcae7b891 518 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 496 3.9E-154 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CFK41_RS13090 db0cf7d62d97f88d5d5ee74847e50185 276 Pfam PF02361 Cobalt transport protein 16 232 1.3E-29 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CFK41_RS00875 e355829c050fd8692f26c572c2ed04e5 322 Gene3D G3DSA:3.90.1200.10 120 304 1.2E-9 T 28-03-2018 CFK41_RS00875 e355829c050fd8692f26c572c2ed04e5 322 SUPERFAMILY SSF56112 38 303 4.69E-20 T 28-03-2018 IPR011009 Protein kinase-like domain CFK41_RS00875 e355829c050fd8692f26c572c2ed04e5 322 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 55 303 2.9E-29 T 28-03-2018 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 CFK41_RS06190 330d77088973c5515dce35f50c4cba87 329 SUPERFAMILY SSF51735 6 242 3.18E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS06190 330d77088973c5515dce35f50c4cba87 329 Pfam PF02719 Polysaccharide biosynthesis protein 9 275 3.3E-94 T 28-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain CFK41_RS06190 330d77088973c5515dce35f50c4cba87 329 TIGRFAM TIGR03589 PseB: UDP-N-acetylglucosamine 4,6-dehydratase (inverting) 4 324 2.7E-139 T 28-03-2018 IPR020025 UDP-N-acetylglucosamine 4,6-dehydratase (inverting) KEGG: 00010+4.2.1.11|KEGG: 00520+4.2.1.115|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6143|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|MetaCyc: PWY-7330|MetaCyc: PWY-7331|MetaCyc: PWY-7332|MetaCyc: PWY-7719 CFK41_RS06190 330d77088973c5515dce35f50c4cba87 329 Gene3D G3DSA:3.40.50.720 2 328 5.1E-57 T 28-03-2018 CFK41_RS01150 8b840195615552bc1cd7f9f54f0c1991 525 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 34 435 5.1E-83 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CFK41_RS01150 8b840195615552bc1cd7f9f54f0c1991 525 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 417 437 - T 28-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 CFK41_RS01150 8b840195615552bc1cd7f9f54f0c1991 525 Pfam PF00474 Sodium:solute symporter family 34 435 7.3E-96 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CFK41_RS01150 8b840195615552bc1cd7f9f54f0c1991 525 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 7 495 2.7E-193 T 28-03-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 CFK41_RS17395 d7e16ed9a0d5673a9d71c1a059ea97b6 292 Pfam PF10099 Anti-sigma-K factor rskA 58 289 4.8E-21 T 28-03-2018 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 CFK41_RS16395 42d8fe226eca45a24b14a116b98d451e 327 Pfam PF05448 Acetyl xylan esterase (AXE1) 1 324 4.1E-94 T 28-03-2018 IPR008391 Acetyl xylan esterase CFK41_RS16395 42d8fe226eca45a24b14a116b98d451e 327 Gene3D G3DSA:3.40.50.1820 4 324 4.9E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS16395 42d8fe226eca45a24b14a116b98d451e 327 SUPERFAMILY SSF53474 3 323 1.07E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS03375 adf36782e2574a012b94447eaa28f000 312 Gene3D G3DSA:3.60.21.10 48 296 1.7E-17 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CFK41_RS03375 adf36782e2574a012b94447eaa28f000 312 Pfam PF00149 Calcineurin-like phosphoesterase 51 242 4.8E-6 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CFK41_RS03375 adf36782e2574a012b94447eaa28f000 312 SUPERFAMILY SSF56300 45 296 1.74E-23 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CFK41_RS00470 a58f2597a2a236e8cef1a5927f11f695 215 Pfam PF04314 Copper chaperone PCu(A)C 70 176 2.8E-31 T 28-03-2018 IPR007410 Copper chaperone PCuAC CFK41_RS00470 a58f2597a2a236e8cef1a5927f11f695 215 SUPERFAMILY SSF110087 63 186 5.36E-36 T 28-03-2018 IPR007410 Copper chaperone PCuAC CFK41_RS04290 1f80cc6bd49ddb597a2a28d39636fef2 471 Pfam PF02386 Cation transport protein 62 447 3.9E-49 T 28-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 CFK41_RS00730 ef9a742d81e6b302837f8f7efa493c10 237 PIRSF PIRSF024492 57 235 7.1E-44 T 28-03-2018 IPR014519 Uncharacterised conserved protein UCP024492 CFK41_RS00730 ef9a742d81e6b302837f8f7efa493c10 237 Pfam PF04343 Protein of unknown function, DUF488 71 194 1.1E-23 T 28-03-2018 IPR007438 Protein of unknown function DUF488 CFK41_RS07780 796e7a3e50d24704356b9a26e24856ac 253 SUPERFAMILY SSF53335 21 245 1.21E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS07780 796e7a3e50d24704356b9a26e24856ac 253 Gene3D G3DSA:3.40.50.150 14 251 3.9E-31 T 28-03-2018 CFK41_RS07780 796e7a3e50d24704356b9a26e24856ac 253 Pfam PF13847 Methyltransferase domain 41 140 6.1E-9 T 28-03-2018 IPR025714 Methyltransferase domain CFK41_RS15820 73c0cd1c3c1b783757aecfc14c25d0ee 275 Pfam PF01066 CDP-alcohol phosphatidyltransferase 87 156 9.0E-8 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CFK41_RS15820 73c0cd1c3c1b783757aecfc14c25d0ee 275 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 134 156 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CFK41_RS01570 72f618df0fbaaf230b17191698f81a72 239 SUPERFAMILY SSF53639 14 233 1.41E-58 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CFK41_RS01570 72f618df0fbaaf230b17191698f81a72 239 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 22 207 3.6E-47 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CFK41_RS01570 72f618df0fbaaf230b17191698f81a72 239 SMART SM01007 21 209 7.8E-62 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CFK41_RS01570 72f618df0fbaaf230b17191698f81a72 239 Gene3D G3DSA:3.40.225.10 9 239 5.0E-61 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CFK41_RS11465 bb2e61846b82b65a86266ad8e5553db2 161 Pfam PF04472 Cell division protein SepF 75 146 7.7E-25 T 28-03-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 CFK41_RS11465 bb2e61846b82b65a86266ad8e5553db2 161 Hamap MF_01197 Cell division protein SepF [sepF]. 1 154 19.952 T 28-03-2018 IPR023052 Cell division protein SepF GO:0090529 CFK41_RS01480 9eb8f1dfa30607af5c37b97d1b098d89 457 Gene3D G3DSA:2.115.10.20 60 262 2.8E-4 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CFK41_RS01480 9eb8f1dfa30607af5c37b97d1b098d89 457 Pfam PF15892 BNR repeat-containing family member 71 247 1.2E-7 T 28-03-2018 CFK41_RS02580 149ff1d65f118e677cf269ace09056b6 205 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 13 46 4.2E-8 T 28-03-2018 IPR023833 Signal peptide, camelysin CFK41_RS08055 a910f6d237733d4f294f191cda892ccb 230 Pfam PF07884 Vitamin K epoxide reductase family 46 177 7.2E-22 T 28-03-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 CFK41_RS08055 a910f6d237733d4f294f191cda892ccb 230 SMART SM00756 40 181 8.8E-29 T 28-03-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 CFK41_RS13780 5262b81d4653726e7bfcc983065e39fb 161 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 15 156 3.0E-12 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CFK41_RS13780 5262b81d4653726e7bfcc983065e39fb 161 SUPERFAMILY SSF55961 15 157 1.72E-24 T 28-03-2018 CFK41_RS13780 5262b81d4653726e7bfcc983065e39fb 161 Gene3D G3DSA:3.30.530.20 7 161 8.4E-27 T 28-03-2018 IPR023393 START-like domain CFK41_RS09705 005cb1da19aeaa0253d8af204a62800e 393 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 59 378 3.6E-30 T 28-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 CFK41_RS09705 005cb1da19aeaa0253d8af204a62800e 393 Gene3D G3DSA:3.40.720.10 52 325 1.9E-22 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CFK41_RS09705 005cb1da19aeaa0253d8af204a62800e 393 SUPERFAMILY SSF53649 50 389 1.23E-45 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CFK41_RS06590 34ebee40aa31a43323945ff4fa97dbd4 161 Pfam PF04892 VanZ like family 56 130 2.5E-10 T 28-03-2018 IPR006976 VanZ-like CFK41_RS02475 5755790a65d775f0a9252d6a9d2f6f79 556 SUPERFAMILY SSF53474 298 430 6.34E-6 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS02475 5755790a65d775f0a9252d6a9d2f6f79 556 Gene3D G3DSA:3.40.50.1820 290 547 2.1E-5 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CFK41_RS12505 8125d4d49235cde3c2d7ec12b21f921f 581 Gene3D G3DSA:1.20.1250.20 18 213 6.2E-38 T 28-03-2018 CFK41_RS12505 8125d4d49235cde3c2d7ec12b21f921f 581 PRINTS PR01036 Tetracycline resistance protein TetB signature 150 174 9.1E-8 T 28-03-2018 CFK41_RS12505 8125d4d49235cde3c2d7ec12b21f921f 581 PRINTS PR01036 Tetracycline resistance protein TetB signature 89 111 9.1E-8 T 28-03-2018 CFK41_RS12505 8125d4d49235cde3c2d7ec12b21f921f 581 PRINTS PR01036 Tetracycline resistance protein TetB signature 215 233 9.1E-8 T 28-03-2018 CFK41_RS12505 8125d4d49235cde3c2d7ec12b21f921f 581 PRINTS PR01036 Tetracycline resistance protein TetB signature 414 433 9.1E-8 T 28-03-2018 CFK41_RS12505 8125d4d49235cde3c2d7ec12b21f921f 581 PRINTS PR01036 Tetracycline resistance protein TetB signature 372 392 9.1E-8 T 28-03-2018 CFK41_RS12505 8125d4d49235cde3c2d7ec12b21f921f 581 Gene3D G3DSA:1.20.1250.20 265 532 5.1E-37 T 28-03-2018 CFK41_RS12505 8125d4d49235cde3c2d7ec12b21f921f 581 ProSitePatterns PS00216 Sugar transport proteins signature 1. 80 96 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CFK41_RS12505 8125d4d49235cde3c2d7ec12b21f921f 581 SUPERFAMILY SSF103473 25 213 5.49E-72 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS12505 8125d4d49235cde3c2d7ec12b21f921f 581 SUPERFAMILY SSF103473 490 526 5.49E-72 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS12505 8125d4d49235cde3c2d7ec12b21f921f 581 SUPERFAMILY SSF103473 262 433 5.49E-72 T 28-03-2018 IPR020846 Major facilitator superfamily domain CFK41_RS12505 8125d4d49235cde3c2d7ec12b21f921f 581 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 27 514 9.9E-76 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CFK41_RS12505 8125d4d49235cde3c2d7ec12b21f921f 581 Pfam PF07690 Major Facilitator Superfamily 31 423 2.5E-56 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CFK41_RS07740 a69975eca8ff50f9758c4320df9595be 416 Pfam PF07730 Histidine kinase 208 273 6.9E-16 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CFK41_RS07740 a69975eca8ff50f9758c4320df9595be 416 Gene3D G3DSA:3.30.565.10 262 415 2.4E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS14030 a86040c493cd11f227577a4aa62780d8 397 Pfam PF07730 Histidine kinase 192 254 3.1E-11 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CFK41_RS14030 a86040c493cd11f227577a4aa62780d8 397 Gene3D G3DSA:3.30.565.10 261 393 6.8E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CFK41_RS00095 6192772bbd0b23a8ab078cc463c1dbac 141 SUPERFAMILY SSF54593 5 138 2.09E-27 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS00095 6192772bbd0b23a8ab078cc463c1dbac 141 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 133 5.7E-6 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CFK41_RS00095 6192772bbd0b23a8ab078cc463c1dbac 141 Gene3D G3DSA:3.10.180.10 2 141 7.7E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS16735 df96ae8f5a2518888a0fd52e1e353d9e 1046 Pfam PF13091 PLD-like domain 139 267 3.7E-14 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CFK41_RS16735 df96ae8f5a2518888a0fd52e1e353d9e 1046 Pfam PF00271 Helicase conserved C-terminal domain 549 642 4.8E-12 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS16735 df96ae8f5a2518888a0fd52e1e353d9e 1046 Gene3D G3DSA:3.40.50.300 516 836 4.5E-22 T 28-03-2018 CFK41_RS16735 df96ae8f5a2518888a0fd52e1e353d9e 1046 SMART SM00487 305 497 1.8E-9 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CFK41_RS16735 df96ae8f5a2518888a0fd52e1e353d9e 1046 Pfam PF11907 Domain of unknown function (DUF3427) 861 1039 2.0E-15 T 28-03-2018 IPR021835 Protein of unknown function DUF3427 CFK41_RS16735 df96ae8f5a2518888a0fd52e1e353d9e 1046 SMART SM00490 563 644 1.2E-11 T 28-03-2018 IPR001650 Helicase, C-terminal CFK41_RS16735 df96ae8f5a2518888a0fd52e1e353d9e 1046 Gene3D G3DSA:3.40.50.300 266 482 2.3E-20 T 28-03-2018 CFK41_RS16735 df96ae8f5a2518888a0fd52e1e353d9e 1046 SUPERFAMILY SSF56024 140 270 8.75E-13 T 28-03-2018 CFK41_RS16735 df96ae8f5a2518888a0fd52e1e353d9e 1046 SUPERFAMILY SSF52540 532 663 1.2E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS16735 df96ae8f5a2518888a0fd52e1e353d9e 1046 SUPERFAMILY SSF52540 361 504 1.2E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS16735 df96ae8f5a2518888a0fd52e1e353d9e 1046 Gene3D G3DSA:3.30.870.10 33 265 5.7E-17 T 28-03-2018 CFK41_RS16735 df96ae8f5a2518888a0fd52e1e353d9e 1046 Pfam PF04851 Type III restriction enzyme, res subunit 308 463 1.9E-29 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CFK41_RS13965 e0ba449085836ad136a7e2dab02d9981 292 Gene3D G3DSA:1.10.3720.10 17 280 3.0E-46 T 28-03-2018 CFK41_RS13965 e0ba449085836ad136a7e2dab02d9981 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 285 1.1E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS13965 e0ba449085836ad136a7e2dab02d9981 292 SUPERFAMILY SSF161098 23 292 1.1E-72 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS11295 deba79c3a563b7f30cec6f1a06283dc1 55 Pfam PF11314 Protein of unknown function (DUF3117) 4 53 8.5E-28 T 28-03-2018 IPR021465 Protein of unknown function DUF3117 CFK41_RS16155 b7f11f3a87f154b1b80cdc7e6f3f0038 221 Pfam PF13302 Acetyltransferase (GNAT) domain 24 170 1.7E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CFK41_RS16155 b7f11f3a87f154b1b80cdc7e6f3f0038 221 SUPERFAMILY SSF55729 19 176 2.09E-18 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CFK41_RS16155 b7f11f3a87f154b1b80cdc7e6f3f0038 221 Gene3D G3DSA:3.40.630.30 8 206 1.5E-19 T 28-03-2018 CFK41_RS03495 c64e26385984baf5b6930f32856803b2 361 Pfam PF00482 Type II secretion system (T2SS), protein F 222 340 2.8E-12 T 28-03-2018 IPR018076 Type II secretion system F domain CFK41_RS03495 c64e26385984baf5b6930f32856803b2 361 Pfam PF00482 Type II secretion system (T2SS), protein F 46 164 7.3E-9 T 28-03-2018 IPR018076 Type II secretion system F domain CFK41_RS06810 bc1ba4af3f8e51d74b9c34b90b859258 191 Pfam PF02566 OsmC-like protein 80 184 3.9E-19 T 28-03-2018 IPR003718 OsmC/Ohr family CFK41_RS06810 bc1ba4af3f8e51d74b9c34b90b859258 191 Gene3D G3DSA:3.30.300.20 33 191 1.6E-34 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CFK41_RS06810 bc1ba4af3f8e51d74b9c34b90b859258 191 SUPERFAMILY SSF82784 33 187 2.09E-38 T 28-03-2018 IPR003718 OsmC/Ohr family CFK41_RS11250 83b09506ee8759c80a0fcf23c607c3c1 571 Gene3D G3DSA:1.20.120.610 8 192 3.4E-4 T 28-03-2018 CFK41_RS11250 83b09506ee8759c80a0fcf23c607c3c1 571 SUPERFAMILY SSF56300 249 445 8.07E-23 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CFK41_RS11250 83b09506ee8759c80a0fcf23c607c3c1 571 Pfam PF00149 Calcineurin-like phosphoesterase 249 419 4.4E-8 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CFK41_RS11250 83b09506ee8759c80a0fcf23c607c3c1 571 Gene3D G3DSA:3.60.21.10 243 479 3.3E-22 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CFK41_RS00385 8645b1a9d184f862afeedb6eca2e3f58 226 SUPERFAMILY SSF52317 4 188 1.37E-49 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS00385 8645b1a9d184f862afeedb6eca2e3f58 226 Pfam PF01965 DJ-1/PfpI family 5 164 1.3E-30 T 28-03-2018 IPR002818 DJ-1/PfpI CFK41_RS00385 8645b1a9d184f862afeedb6eca2e3f58 226 Gene3D G3DSA:3.40.50.880 1 225 8.9E-57 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CFK41_RS02480 886505aea5095df5db37cd4b67312760 611 Gene3D G3DSA:3.60.20.10 91 217 7.9E-4 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CFK41_RS02480 886505aea5095df5db37cd4b67312760 611 SUPERFAMILY SSF52402 222 307 1.4E-9 T 28-03-2018 CFK41_RS02480 886505aea5095df5db37cd4b67312760 611 Gene3D G3DSA:3.40.50.620 218 585 3.3E-6 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CFK41_RS15885 3470b6c495ba71d236db789f99cd0a85 295 SMART SM00752 16 272 0.0045 T 28-03-2018 IPR011020 HTTM Reactome: R-HSA-159740 CFK41_RS07670 448901f9e284f77caa12b0ed8c89697c 347 Gene3D G3DSA:1.10.3720.10 49 318 2.1E-30 T 28-03-2018 CFK41_RS07670 448901f9e284f77caa12b0ed8c89697c 347 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 137 329 1.8E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS07670 448901f9e284f77caa12b0ed8c89697c 347 SUPERFAMILY SSF161098 114 310 9.81E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS10165 dae35681f214068d3dc5981b9ad2e19b 501 Pfam PF00860 Permease family 41 454 3.1E-27 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CFK41_RS09475 7aa189f5a1b895bc31429d0f6c0d60cc 210 Pfam PF09534 Tryptophan-associated transmembrane protein (Trp_oprn_chp) 19 195 1.8E-33 T 28-03-2018 IPR019051 Trp biosynthesis associated, transmembrane protein, Oprn/Chp CFK41_RS15945 61619993f079ffb1de5aa90dcb4fcd99 252 Gene3D G3DSA:3.40.50.300 2 247 8.6E-56 T 28-03-2018 CFK41_RS15945 61619993f079ffb1de5aa90dcb4fcd99 252 Pfam PF00005 ABC transporter 27 176 2.5E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CFK41_RS15945 61619993f079ffb1de5aa90dcb4fcd99 252 SUPERFAMILY SSF52540 21 231 1.05E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS15945 61619993f079ffb1de5aa90dcb4fcd99 252 SMART SM00382 36 225 2.7E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CFK41_RS15945 61619993f079ffb1de5aa90dcb4fcd99 252 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CFK41_RS10050 fe4810e32999f794c06fdbc119aa525f 352 Gene3D G3DSA:3.40.50.300 23 203 4.3E-10 T 28-03-2018 CFK41_RS10050 fe4810e32999f794c06fdbc119aa525f 352 Pfam PF03969 AFG1-like ATPase 15 215 2.3E-42 T 28-03-2018 IPR005654 ATPase, AFG1-like GO:0005524 CFK41_RS10050 fe4810e32999f794c06fdbc119aa525f 352 Pfam PF03969 AFG1-like ATPase 229 336 4.0E-13 T 28-03-2018 IPR005654 ATPase, AFG1-like GO:0005524 CFK41_RS10050 fe4810e32999f794c06fdbc119aa525f 352 SUPERFAMILY SSF52540 44 190 2.28E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CFK41_RS16020 9911d1c8769e36f188c919b40e274789 379 Pfam PF01844 HNH endonuclease 235 281 2.0E-6 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CFK41_RS16020 9911d1c8769e36f188c919b40e274789 379 Gene3D G3DSA:3.40.1800.10 211 293 2.0E-7 T 28-03-2018 CFK41_RS14445 f2d28bec70687a63a5f9fba89cf6a0be 446 Pfam PF03600 Citrate transporter 262 444 4.6E-9 T 28-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 CFK41_RS14445 f2d28bec70687a63a5f9fba89cf6a0be 446 Pfam PF07158 Dicarboxylate carrier protein MatC N-terminus 1 146 2.7E-32 T 28-03-2018 IPR009827 Dicarboxylate carrier MatC N-terminal CFK41_RS01265 2d5547c2e1678e038ffc5f807b8968f7 216 Pfam PF09335 SNARE associated Golgi protein 32 159 3.0E-19 T 28-03-2018 IPR032816 SNARE associated Golgi protein CFK41_RS06240 09b8a7a34482ebfcdd2818b0b15dfe67 302 Pfam PF01061 ABC-2 type transporter 35 246 5.2E-19 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CFK41_RS07620 ce089abc458ec40fc4bf1476641ac5dd 365 Pfam PF03601 Conserved hypothetical protein 698 46 346 6.6E-76 T 28-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 CFK41_RS02555 17dab5e5ed2869854875192f17b7628c 363 Pfam PF05090 Vitamin K-dependent gamma-carboxylase 88 303 4.0E-14 T 28-03-2018 IPR007782 Vitamin K-dependent gamma-carboxylase GO:0008488|GO:0017187 KEGG: 00130+4.1.1.90|Reactome: R-HSA-159740 CFK41_RS02555 17dab5e5ed2869854875192f17b7628c 363 SMART SM00752 32 306 9.2E-44 T 28-03-2018 IPR011020 HTTM Reactome: R-HSA-159740 CFK41_RS07070 d7731709b1eee6165e381cd0369f3eb5 93 SUPERFAMILY SSF51344 3 83 1.31E-20 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07070 d7731709b1eee6165e381cd0369f3eb5 93 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 83 4.6E-22 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07070 d7731709b1eee6165e381cd0369f3eb5 93 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 78 5.0E-13 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS07070 d7731709b1eee6165e381cd0369f3eb5 93 Gene3D G3DSA:2.60.15.10 1 88 1.2E-22 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CFK41_RS05905 4355b435463bea6a0628a88c6acd04e3 160 Gene3D G3DSA:3.40.1000.10 18 158 1.5E-20 T 28-03-2018 CFK41_RS10420 a54787f072982e1c9a604f57912cf5cb 243 Pfam PF04854 Protein of unknown function, DUF624 32 97 1.6E-10 T 28-03-2018 IPR006938 Protein of unknown function DUF624 CFK41_RS08435 fbbe8e1522258d3bacc6a3e9b2b45aea 259 Pfam PF03883 Peroxide stress protein YaaA 1 222 1.9E-21 T 28-03-2018 IPR005583 Peroxide stress protein YaaA CFK41_RS08935 f123cc4b7000c1b813367a70d7d0a674 298 SUPERFAMILY SSF54001 79 169 7.07E-13 T 28-03-2018 CFK41_RS08935 f123cc4b7000c1b813367a70d7d0a674 298 Pfam PF01841 Transglutaminase-like superfamily 64 147 5.0E-7 T 28-03-2018 IPR002931 Transglutaminase-like CFK41_RS17595 21a512bfaf25293c3eac9c3f5a4ca7a7 94 Gene3D G3DSA:3.30.1390.10 39 93 2.1E-9 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CFK41_RS15790 0ca8331f07244b39589533ab0030575e 284 SUPERFAMILY SSF89550 6 51 4.19E-21 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CFK41_RS15790 0ca8331f07244b39589533ab0030575e 284 SUPERFAMILY SSF89550 79 272 4.19E-21 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CFK41_RS15790 0ca8331f07244b39589533ab0030575e 284 Gene3D G3DSA:3.20.20.140 3 274 5.1E-22 T 28-03-2018 CFK41_RS07025 bfddbec34cf18bf16348ffbd7e5f1556 374 Pfam PF00953 Glycosyl transferase family 4 81 241 2.9E-35 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CFK41_RS14320 8184567ac81d28c7620844d036f0bb13 266 Pfam PF02517 CAAX protease self-immunity 166 249 1.4E-9 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CFK41_RS15010 1e544a3045b1220227ba0126c29a1640 115 SUPERFAMILY SSF46785 9 100 4.02E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS15010 1e544a3045b1220227ba0126c29a1640 115 Pfam PF03551 Transcriptional regulator PadR-like family 24 86 7.1E-16 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CFK41_RS15010 1e544a3045b1220227ba0126c29a1640 115 Gene3D G3DSA:1.10.10.10 2 112 3.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS05130 5530effa6223bd4c44dbbc98d6826b3a 128 Gene3D G3DSA:3.10.180.10 1 127 9.6E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS05130 5530effa6223bd4c44dbbc98d6826b3a 128 SUPERFAMILY SSF54593 1 125 3.71E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS05130 5530effa6223bd4c44dbbc98d6826b3a 128 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 123 3.3E-8 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CFK41_RS03385 52584d1371f7bd196017d3b5fa906513 100 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 81 16.893 T 28-03-2018 IPR003482 Transcription factor WhiB CFK41_RS03385 52584d1371f7bd196017d3b5fa906513 100 Pfam PF02467 Transcription factor WhiB 14 76 5.5E-22 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain CFK41_RS06320 955c226083a59e9b767a64719a3e3549 402 Pfam PF14258 Domain of unknown function (DUF4350) 65 132 7.0E-9 T 28-03-2018 IPR025646 Domain of unknown function DUF4350 CFK41_RS13115 e20d4131ff343254799acda8cb29b550 195 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 102 179 5.3E-13 T 28-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain CFK41_RS07370 950e324312a190854ee3bfe62e19b538 193 Pfam PF11066 Protein of unknown function (DUF2867) 30 151 2.2E-4 T 28-03-2018 IPR021295 Protein of unknown function DUF2867 CFK41_RS12805 a70913c68d358df38bbdcf4f4bd31c92 409 SUPERFAMILY SSF50939 49 407 1.04E-87 T 28-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CFK41_RS12805 a70913c68d358df38bbdcf4f4bd31c92 409 Gene3D G3DSA:2.120.10.10 44 409 1.0E-66 T 28-03-2018 CFK41_RS12805 a70913c68d358df38bbdcf4f4bd31c92 409 Pfam PF13088 BNR repeat-like domain 94 378 1.2E-24 T 28-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CFK41_RS00525 2d846e2992544b497ed9e2356693aa26 320 SUPERFAMILY SSF52266 289 316 2.38E-5 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CFK41_RS00525 2d846e2992544b497ed9e2356693aa26 320 SUPERFAMILY SSF52266 181 260 2.38E-5 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CFK41_RS00525 2d846e2992544b497ed9e2356693aa26 320 Gene3D G3DSA:3.40.50.1110 9 317 1.3E-7 T 28-03-2018 CFK41_RS15460 5e07cbef3585853388298f05af9bf974 233 Gene3D G3DSA:3.30.530.20 6 208 3.0E-17 T 28-03-2018 IPR023393 START-like domain CFK41_RS15460 5e07cbef3585853388298f05af9bf974 233 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 33 104 6.5E-8 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CFK41_RS15460 5e07cbef3585853388298f05af9bf974 233 SUPERFAMILY SSF55961 14 174 1.18E-16 T 28-03-2018 CFK41_RS16180 a48eac294dc8b6d48f7f4ca8c72d4aee 256 Gene3D G3DSA:1.20.120.20 3 223 5.4E-6 T 28-03-2018 CFK41_RS08820 45cf1b728e175e6436c36bcb08e4cc50 261 ProDom PD040491 SCO1799 RV1486C/MT1533 MB1522C CGL1536 ML1804 MAV321 22 102 3.0E-4 T 28-03-2018 CFK41_RS02760 f8a3c44891470ac5ad68bcc113711e97 454 PIRSF PIRSF006060 1 453 3.3E-56 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CFK41_RS02760 f8a3c44891470ac5ad68bcc113711e97 454 Pfam PF00324 Amino acid permease 16 420 1.9E-36 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CFK41_RS02335 63a6fc8926505ceea71a7b8f72a2bfd6 85 Pfam PF02583 Metal-sensitive transcriptional repressor 11 80 6.9E-24 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CFK41_RS15340 448e71b90eb55d4cd1ea7cde1cad2e6a 386 Gene3D G3DSA:1.10.287.850 1 90 6.6E-5 T 28-03-2018 CFK41_RS14860 dc04b9dc1ec0bb14a94fa6f8248c21bb 385 Pfam PF06081 Aromatic acid exporter family member 1 24 161 7.4E-13 T 28-03-2018 IPR010343 Aromatic acid exporter family member 1 CFK41_RS02535 cfe22627094e6feff094e0944921a13a 181 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 24 57 5.4E-5 T 28-03-2018 IPR023833 Signal peptide, camelysin CFK41_RS16640 327bf08869bd79e09924aebc39fa2da9 224 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 196 2.0E-46 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CFK41_RS16640 327bf08869bd79e09924aebc39fa2da9 224 SMART SM00855 2 158 1.2E-18 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CFK41_RS16640 327bf08869bd79e09924aebc39fa2da9 224 Gene3D G3DSA:3.40.50.1240 1 213 1.3E-42 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CFK41_RS16640 327bf08869bd79e09924aebc39fa2da9 224 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 5 14 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CFK41_RS16640 327bf08869bd79e09924aebc39fa2da9 224 SUPERFAMILY SSF53254 1 199 3.43E-43 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CFK41_RS15910 f5e2b9341f0e6f41b8658a5b1a1fb329 349 SUPERFAMILY SSF52833 203 331 2.78E-6 T 28-03-2018 IPR012336 Thioredoxin-like fold CFK41_RS15910 f5e2b9341f0e6f41b8658a5b1a1fb329 349 Gene3D G3DSA:3.40.30.10 168 344 1.3E-7 T 28-03-2018 CFK41_RS04155 c0f82c48d90ebd4c2c0ff635255efaf8 153 Gene3D G3DSA:3.10.180.10 3 152 2.4E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS04155 c0f82c48d90ebd4c2c0ff635255efaf8 153 SUPERFAMILY SSF54593 6 152 3.66E-8 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS15955 11091775329c6775b6c79f501045423d 643 SUPERFAMILY SSF48230 104 325 7.42E-19 T 28-03-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 CFK41_RS15955 11091775329c6775b6c79f501045423d 643 Gene3D G3DSA:1.50.10.100 85 352 7.9E-19 T 28-03-2018 CFK41_RS15955 11091775329c6775b6c79f501045423d 643 Pfam PF07940 Heparinase II/III-like protein 401 529 4.2E-8 T 28-03-2018 IPR012480 Heparinase II/III-like GO:0016829 CFK41_RS00720 07095a0a561117e9bae9495e02fa7a7e 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 258 2.2E-41 T 28-03-2018 CFK41_RS00720 07095a0a561117e9bae9495e02fa7a7e 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.3E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS00720 07095a0a561117e9bae9495e02fa7a7e 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 1.3E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS00720 07095a0a561117e9bae9495e02fa7a7e 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 1.3E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS00720 07095a0a561117e9bae9495e02fa7a7e 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 1.3E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS00720 07095a0a561117e9bae9495e02fa7a7e 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 1.3E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS00720 07095a0a561117e9bae9495e02fa7a7e 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 1.3E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS00720 07095a0a561117e9bae9495e02fa7a7e 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 2.2E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS00720 07095a0a561117e9bae9495e02fa7a7e 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 2.2E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS00720 07095a0a561117e9bae9495e02fa7a7e 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 2.2E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CFK41_RS00720 07095a0a561117e9bae9495e02fa7a7e 262 SUPERFAMILY SSF51735 7 258 1.34E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain CFK41_RS00720 07095a0a561117e9bae9495e02fa7a7e 262 Gene3D G3DSA:3.40.50.720 1 261 2.9E-56 T 28-03-2018 CFK41_RS11100 e99b26236303af24f60aad9de8d14fe1 438 Gene3D G3DSA:2.60.120.380 42 181 8.7E-4 T 28-03-2018 CFK41_RS04345 5d69beaa61821f462112db34cbd68be7 264 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 28 243 3.9E-48 T 28-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CFK41_RS14335 3eb5b9473f1e5c653b708038005caa64 80 Gene3D G3DSA:1.10.357.10 1 76 3.1E-5 T 28-03-2018 CFK41_RS00560 aa6440cc1c1dd4442cd765dad8ce48e7 173 Pfam PF00210 Ferritin-like domain 9 145 2.8E-34 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CFK41_RS00560 aa6440cc1c1dd4442cd765dad8ce48e7 173 Gene3D G3DSA:1.20.1260.10 1 163 4.9E-38 T 28-03-2018 IPR012347 Ferritin-related CFK41_RS00560 aa6440cc1c1dd4442cd765dad8ce48e7 173 SUPERFAMILY SSF47240 3 162 2.92E-45 T 28-03-2018 IPR009078 Ferritin-like superfamily CFK41_RS12875 545ec41f5115b429d3c0ee9014aac306 303 Pfam PF12811 Bax inhibitor 1 like 49 300 9.7E-69 T 28-03-2018 IPR010539 Protein of unknown function UCP009160 CFK41_RS10430 08a5f9c7d3369555d3dbd1a29bf45011 261 Pfam PF02754 Cysteine-rich domain 138 222 1.1E-14 T 28-03-2018 IPR004017 Cysteine-rich domain CFK41_RS10430 08a5f9c7d3369555d3dbd1a29bf45011 261 Pfam PF02754 Cysteine-rich domain 7 85 1.1E-12 T 28-03-2018 IPR004017 Cysteine-rich domain CFK41_RS10565 e47433290f4b9fe2e3b1b5ddcd059b64 160 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 18 132 5.5E-22 T 28-03-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III CFK41_RS00055 81cb89fdef7b1ca1daa15eef397457b9 116 SUPERFAMILY SSF51182 19 103 2.31E-6 T 28-03-2018 IPR011051 RmlC-like cupin domain CFK41_RS00055 81cb89fdef7b1ca1daa15eef397457b9 116 Gene3D G3DSA:2.60.120.10 7 113 1.5E-6 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CFK41_RS08410 3d8f58aa28a34c40b61bd07a1074afd3 421 Pfam PF01757 Acyltransferase family 70 369 1.3E-20 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CFK41_RS14825 2750efe517d58ef698dba7a362a7e7af 412 SMART SM01119 303 398 8.1E-31 T 28-03-2018 IPR026956 D-serine dehydratase-like domain CFK41_RS14825 2750efe517d58ef698dba7a362a7e7af 412 Pfam PF14031 Putative serine dehydratase domain 304 396 3.2E-14 T 28-03-2018 IPR026956 D-serine dehydratase-like domain CFK41_RS14825 2750efe517d58ef698dba7a362a7e7af 412 Gene3D G3DSA:3.20.20.10 32 286 1.9E-33 T 28-03-2018 IPR029066 PLP-binding barrel CFK41_RS14825 2750efe517d58ef698dba7a362a7e7af 412 SUPERFAMILY SSF51419 47 281 4.14E-23 T 28-03-2018 IPR029066 PLP-binding barrel CFK41_RS14230 659167eaba6292a67020d916812f4077 298 Gene3D G3DSA:1.10.3720.10 18 286 2.5E-40 T 28-03-2018 CFK41_RS14230 659167eaba6292a67020d916812f4077 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 292 1.1E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS14230 659167eaba6292a67020d916812f4077 298 SUPERFAMILY SSF161098 25 298 2.52E-70 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS00775 7cbe2edb5313169128d841d49750de94 214 Pfam PF09335 SNARE associated Golgi protein 40 166 2.3E-21 T 28-03-2018 IPR032816 SNARE associated Golgi protein CFK41_RS09955 bd203f9c77eac59fb610e065ec6700bb 114 Pfam PF02699 Preprotein translocase subunit 5 69 3.2E-14 T 28-03-2018 IPR003849 Preprotein translocase YajC CFK41_RS09955 bd203f9c77eac59fb610e065ec6700bb 114 SMART SM01323 1 71 1.4E-6 T 28-03-2018 IPR003849 Preprotein translocase YajC CFK41_RS00750 991e1d862f3eeacd35d3e3858f0a1e42 427 Pfam PF13515 Fusaric acid resistance protein-like 281 405 5.6E-20 T 28-03-2018 CFK41_RS03260 8d9b7b4ae34461a26537126b5cb13cfb 231 Pfam PF13835 Domain of unknown function (DUF4194) 36 191 1.9E-38 T 28-03-2018 IPR025449 Protein of unknown function DUF4194 CFK41_RS01725 849e60e931f09ef0e9ef0d4f9cf16240 219 Pfam PF04854 Protein of unknown function, DUF624 21 97 3.9E-15 T 28-03-2018 IPR006938 Protein of unknown function DUF624 CFK41_RS03530 89a845a7ffc78fcddf659c43f767b504 239 Pfam PF09335 SNARE associated Golgi protein 32 158 2.3E-21 T 28-03-2018 IPR032816 SNARE associated Golgi protein CFK41_RS00135 77e132f1b17ebd8fdc5af34f18b91bb4 156 Gene3D G3DSA:3.40.50.720 5 152 4.4E-4 T 28-03-2018 CFK41_RS04560 1e7b7deae0d1a7d3d919ed5caf4798c0 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 126 312 2.8E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS04560 1e7b7deae0d1a7d3d919ed5caf4798c0 324 SUPERFAMILY SSF161098 74 311 2.88E-51 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS04560 1e7b7deae0d1a7d3d919ed5caf4798c0 324 Gene3D G3DSA:1.10.3720.10 31 324 4.7E-46 T 28-03-2018 CFK41_RS16890 0776fbdc3e5d4bf2d6b4299752436bf3 532 Pfam PF07364 Metallopeptidase family M81 18 300 1.5E-97 T 28-03-2018 IPR015995 Microcystin LR degradation protein MlrC, N-terminal CFK41_RS16890 0776fbdc3e5d4bf2d6b4299752436bf3 532 PIRSF PIRSF012702 14 524 3.4E-132 T 28-03-2018 IPR009197 Microcystin LR degradation protein MlrC CFK41_RS16890 0776fbdc3e5d4bf2d6b4299752436bf3 532 Pfam PF07171 MlrC C-terminus 310 506 3.0E-44 T 28-03-2018 IPR010799 Microcystin LR degradation protein MlrC, C-terminal CFK41_RS13500 ac0a35f0a5fea73052a38eec5d8f94e9 507 Gene3D G3DSA:3.40.1800.10 341 421 3.5E-5 T 28-03-2018 CFK41_RS04325 c3a0d676cb2db4fb3387c9baa4ad663d 176 Gene3D G3DSA:2.40.128.110 4 176 4.4E-54 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CFK41_RS04325 c3a0d676cb2db4fb3387c9baa4ad663d 176 SMART SM00867 8 171 6.5E-68 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CFK41_RS04325 c3a0d676cb2db4fb3387c9baa4ad663d 176 Pfam PF04264 YceI-like domain 9 170 9.4E-46 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CFK41_RS04325 c3a0d676cb2db4fb3387c9baa4ad663d 176 SUPERFAMILY SSF101874 7 172 9.55E-53 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CFK41_RS06275 81eb637b7b3e700fa8ccf3e97d451255 151 SUPERFAMILY SSF55486 41 147 6.23E-26 T 28-03-2018 CFK41_RS06275 81eb637b7b3e700fa8ccf3e97d451255 151 Pfam PF06262 Zincin-like metallopeptidase 66 147 6.5E-11 T 28-03-2018 IPR010428 Zincin-like metallopeptidase CFK41_RS10895 72da38dd4c90ae9d6be3a2a356ac90ae 119 Gene3D G3DSA:3.30.428.10 4 119 1.4E-20 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CFK41_RS10895 72da38dd4c90ae9d6be3a2a356ac90ae 119 SUPERFAMILY SSF54197 4 115 3.56E-20 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CFK41_RS10895 72da38dd4c90ae9d6be3a2a356ac90ae 119 Pfam PF01230 HIT domain 26 112 1.4E-12 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CFK41_RS14740 eeee874ac658f2e34a840acea49824bb 200 Pfam PF01810 LysE type translocator 13 199 2.0E-36 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CFK41_RS09130 704be8e0d57f118e75f419a7fc28fdf4 312 Gene3D G3DSA:1.10.3720.10 30 308 2.1E-47 T 28-03-2018 CFK41_RS09130 704be8e0d57f118e75f419a7fc28fdf4 312 SUPERFAMILY SSF161098 75 298 2.75E-55 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS09130 704be8e0d57f118e75f419a7fc28fdf4 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 304 1.3E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS17045 7b44344ca64f4652f16a36791928c202 493 Pfam PF01566 Natural resistance-associated macrophage protein 53 208 2.1E-12 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CFK41_RS05475 1be9c13f34ecba00d17f4e37ebb38138 166 SUPERFAMILY SSF54427 57 150 9.8E-6 T 28-03-2018 IPR032710 NTF2-like domain CFK41_RS05075 1e6074a654ac738e8c2d64f814fb5cfa 270 Gene3D G3DSA:1.10.10.10 8 87 1.8E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS04955 7eb3b19b3dec119577ff962f19f93637 501 Pfam PF01594 AI-2E family transporter 38 356 6.1E-49 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like CFK41_RS08090 b51d066f306cc0699e692cdf96e89698 304 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 1 300 2.5E-77 T 28-03-2018 IPR007296 Domain of unknown function DUF403 CFK41_RS05045 90ef4acbadbccc0f33bdd54aed314483 399 Pfam PF02646 RmuC family 67 356 1.9E-85 T 28-03-2018 IPR003798 DNA recombination RmuC CFK41_RS05175 78f95704dd778c5dfaf23d3693272601 255 TIGRFAM TIGR03843 TIGR03843: conserved hypothetical protein 6 255 4.3E-107 T 28-03-2018 IPR022292 Conserved hypothetical protein CHP03843 CFK41_RS08705 d5b9f2ee91d1894800d8703475059a1a 106 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 20 105 2.9E-9 T 28-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 CFK41_RS08705 d5b9f2ee91d1894800d8703475059a1a 106 SUPERFAMILY SSF101386 23 106 1.03E-21 T 28-03-2018 CFK41_RS08705 d5b9f2ee91d1894800d8703475059a1a 106 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 24 106 5.8E-24 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CFK41_RS08705 d5b9f2ee91d1894800d8703475059a1a 106 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 20 106 18.119 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CFK41_RS08705 d5b9f2ee91d1894800d8703475059a1a 106 Gene3D G3DSA:1.10.287.1080 20 106 7.1E-15 T 28-03-2018 CFK41_RS16315 ca629c03d5eebe6b2e432921d14e73fa 314 SUPERFAMILY SSF161098 36 314 2.49E-52 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS16315 ca629c03d5eebe6b2e432921d14e73fa 314 Gene3D G3DSA:1.10.3720.10 91 309 2.4E-36 T 28-03-2018 CFK41_RS16315 ca629c03d5eebe6b2e432921d14e73fa 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 136 307 3.1E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CFK41_RS10985 10a9ae2d08a1f75c015bec79f148a5d0 138 Gene3D G3DSA:3.30.530.20 7 138 3.1E-14 T 28-03-2018 IPR023393 START-like domain CFK41_RS10985 10a9ae2d08a1f75c015bec79f148a5d0 138 SUPERFAMILY SSF55961 10 136 1.36E-26 T 28-03-2018 CFK41_RS04275 d0e09370b1c49db8c2f5419166d1b512 316 Pfam PF04018 Domain of unknown function (DUF368) 36 275 6.5E-61 T 28-03-2018 IPR007163 Protein of unknown function DUF368 CFK41_RS13720 3ea9d1c5dc17329623f709639765dce1 310 Pfam PF01758 Sodium Bile acid symporter family 23 168 1.5E-11 T 28-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 CFK41_RS03645 74b6eed56a2dc541394aee59d810fed3 137 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 1 117 8.1E-29 T 28-03-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV CFK41_RS06295 771235460900f5bf4c9c18f95e88fb1b 331 Pfam PF01944 Stage II sporulation protein M 108 279 3.2E-33 T 28-03-2018 IPR002798 Stage II sporulation protein M-like CFK41_RS17535 f5983952dfe9c865a9ac14973716d057 835 Gene3D G3DSA:2.60.120.260 659 835 1.7E-6 T 28-03-2018 IPR008979 Galactose-binding domain-like CFK41_RS13550 3ac129339e441e9acb7b40810e17f7a0 253 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 3 249 5.7E-22 T 28-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase CFK41_RS06075 8ec967fc9fa3c3d5981ade14ebc0a598 384 Pfam PF10092 Uncharacterized protein conserved in bacteria (DUF2330) 36 250 2.5E-44 T 28-03-2018 IPR019283 Protein of unknown function DUF2330 CFK41_RS08940 49134c054c394609c28d65e1c543066b 267 Pfam PF01925 Sulfite exporter TauE/SafE 19 258 8.5E-39 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CFK41_RS10185 8793491a5fbe5c32018e8ae822e4281b 202 Pfam PF04417 Protein of unknown function (DUF501) 36 157 1.7E-33 T 28-03-2018 IPR007511 Protein of unknown function DUF501 CFK41_RS05135 d1347a93351edac2fe1c4d4850504ab9 143 Pfam PF08877 MepB protein 22 141 5.0E-37 T 28-03-2018 IPR011235 MepB-like CFK41_RS15715 cd9dd5dcfab24a9c67fc56cb9f0add7d 503 Pfam PF13349 Putative adhesin 328 494 2.0E-9 T 28-03-2018 IPR025164 Putative adhesin CFK41_RS04360 b7ec9b13b84a7e164bcc3faec96414e0 108 Pfam PF13396 Phospholipase_D-nuclease N-terminal 12 56 6.6E-13 T 28-03-2018 IPR027379 Cardiolipin synthase N-terminal CFK41_RS00655 9c59b1b4119bc5d133d2cf8fd22d4487 302 Pfam PF01226 Formate/nitrite transporter 43 271 2.9E-27 T 28-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 CFK41_RS00655 9c59b1b4119bc5d133d2cf8fd22d4487 302 Gene3D G3DSA:1.20.1080.10 33 287 1.2E-29 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CFK41_RS08650 486429c3a39d55789a37cd4514e6ac6f 562 TIGRFAM TIGR03688 pupylate_PafA2: proteasome accessory factor PafA2 133 533 1.6E-155 T 28-03-2018 IPR022366 Pup deamidase GO:0008233|GO:0016811 CFK41_RS08650 486429c3a39d55789a37cd4514e6ac6f 562 Pfam PF03136 Pup-ligase protein 17 513 4.7E-171 T 28-03-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 CFK41_RS03525 5e29b5165458c9a4110f4353e27abadd 315 SUPERFAMILY SSF55486 121 236 1.23E-5 T 28-03-2018 CFK41_RS03525 5e29b5165458c9a4110f4353e27abadd 315 Pfam PF04228 Putative neutral zinc metallopeptidase 13 310 7.8E-76 T 28-03-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative CFK41_RS10300 5bfb278b2f6eb14a987843188c2286aa 181 Pfam PF03466 LysR substrate binding domain 5 100 2.4E-9 T 28-03-2018 IPR005119 LysR, substrate-binding CFK41_RS10300 5bfb278b2f6eb14a987843188c2286aa 181 SUPERFAMILY SSF53850 5 178 5.28E-15 T 28-03-2018 CFK41_RS10300 5bfb278b2f6eb14a987843188c2286aa 181 Gene3D G3DSA:3.40.190.10 2 107 1.1E-10 T 28-03-2018 CFK41_RS04055 d63f8c3bee85fd478e04aa88f9177732 348 Pfam PF01757 Acyltransferase family 17 305 9.9E-25 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CFK41_RS06030 98cc9cc30fa67e1be2d140fcd075ad32 512 Pfam PF02653 Branched-chain amino acid transport system / permease component 142 418 8.8E-41 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CFK41_RS06030 98cc9cc30fa67e1be2d140fcd075ad32 512 Gene3D G3DSA:1.10.3470.10 39 421 4.5E-37 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CFK41_RS03305 bf24bf1b4f6c1ee8ed72deb51b9f640b 268 Pfam PF04230 Polysaccharide pyruvyl transferase 124 198 1.6E-11 T 28-03-2018 IPR007345 Polysaccharide pyruvyl transferase CFK41_RS01040 99304b51889b08fed3bdfcf931898200 176 Pfam PF04138 GtrA-like protein 42 173 2.4E-18 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CFK41_RS13630 b15e9a9cfa2ec385c20164c8aa7ec87c 235 Pfam PF07947 YhhN family 34 212 2.1E-18 T 28-03-2018 IPR012506 YhhN-like GO:0016021 CFK41_RS06660 f891760313139edbde2186f4882d0ad3 159 Gene3D G3DSA:3.40.50.10540 15 156 8.7E-4 T 28-03-2018 IPR023606 CoA-transferase family III domain CFK41_RS07295 bc9c5866bff8394f85ede934d207af55 235 Pfam PF09965 Uncharacterized protein conserved in bacteria (DUF2199) 63 216 6.3E-23 T 28-03-2018 IPR018697 Protein of unknown function DUF2199 CFK41_RS03480 36edb18f0936e5b0cfd93b78fd04f38c 110 TIGRFAM TIGR03816 tadE_like_DECH: helicase/secretion neighborhood TadE-like protein 4 104 2.1E-20 T 28-03-2018 IPR021202 Apoptosis inhibitor Rv3654c-like CFK41_RS00415 bcf11c64b8b6edeebac4129056d809ad 67 Gene3D G3DSA:1.10.1220.10 1 46 2.3E-5 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CFK41_RS09005 661dcbbdae262a0f23c1f24c2b470b6e 315 Gene3D G3DSA:1.20.5.340 70 268 1.6E-4 T 28-03-2018 CFK41_RS09005 661dcbbdae262a0f23c1f24c2b470b6e 315 Pfam PF05949 Bacterial protein of unknown function (DUF881) 142 272 1.3E-33 T 28-03-2018 IPR010273 Protein of unknown function DUF881 CFK41_RS16985 afb625f23b5b5ddf9748cecd89db385e 409 Pfam PF05816 Toxic anion resistance protein (TelA) 77 381 6.1E-65 T 28-03-2018 IPR008863 Toxic anion resistance CFK41_RS13695 ff03dd1057740f1c807b5e396b294497 405 Pfam PF13421 SPFH domain-Band 7 family 115 287 4.2E-5 T 28-03-2018 IPR033880 SPFH domain, YdjI-like CFK41_RS03775 d55ac2205d6078e17e90803bf9b3117c 834 Pfam PF03030 Inorganic H+ pyrophosphatase 131 694 6.3E-9 T 28-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CFK41_RS06360 2f80ce256343667532729b9832650cad 420 Pfam PF06224 Winged helix DNA-binding domain 42 388 4.5E-51 T 28-03-2018 IPR009351 Protein of unknown function DUF1006 CFK41_RS03550 6ab1ae6e67714197a43ab039c9d25bdb 431 Pfam PF13515 Fusaric acid resistance protein-like 55 171 9.1E-8 T 28-03-2018 CFK41_RS09155 66c2dbe424267934cd47a0e758e60d66 260 Pfam PF05154 TM2 domain 189 240 2.4E-13 T 28-03-2018 IPR007829 TM2 domain CFK41_RS15300 3a6ae629703e87313a12138a11d82f1f 195 Pfam PF03608 PTS system enzyme II sorbitol-specific factor 5 171 7.5E-71 T 28-03-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 CFK41_RS15300 3a6ae629703e87313a12138a11d82f1f 195 PIRSF PIRSF038321 1 180 8.4E-71 T 28-03-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 CFK41_RS13225 266d6456d6c2b1ef18133e9730c38841 200 Pfam PF13548 Domain of unknown function (DUF4126) 1 168 2.8E-40 T 28-03-2018 IPR025196 Domain of unknown function DUF4126 CFK41_RS02695 112042be228116e6eff3a69a1f82bf4e 443 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 409 441 5.0E-4 T 28-03-2018 CFK41_RS11620 32ee1210d85e47c78d37e7a872fd9ad3 163 Pfam PF10722 Putative bacterial sensory transduction regulator 23 152 3.9E-22 T 28-03-2018 IPR019660 Putative sensory transduction regulator YbjN CFK41_RS11975 274e2126e2fb051db9cb1894e39353c8 141 Pfam PF14017 Protein of unknown function (DUF4233) 16 119 8.5E-26 T 28-03-2018 IPR025327 Protein of unknown function DUF4233 CFK41_RS08715 678ce4aef5a50a8028209cf6636c8681 154 Pfam PF10756 Bacterial PH domain 74 139 4.8E-18 T 28-03-2018 IPR019692 Protein of unknown function DUF2581 CFK41_RS03980 2301242309604c5a890ea795c583bd0a 458 Pfam PF04235 Protein of unknown function (DUF418) 341 420 5.5E-23 T 28-03-2018 IPR007349 Domain of unknown function DUF418 CFK41_RS03980 2301242309604c5a890ea795c583bd0a 458 Pfam PF04235 Protein of unknown function (DUF418) 217 297 3.3E-9 T 28-03-2018 IPR007349 Domain of unknown function DUF418 CFK41_RS15180 10a850411622bb9af73368482b17ac95 63 Pfam PF04328 Selenoprotein, putative 7 63 6.9E-19 T 28-03-2018 IPR007423 Selenoprotein, putative CFK41_RS13805 b9d0401436048fd9074575e73a5c9630 543 Gene3D G3DSA:3.40.1800.10 373 454 1.6E-6 T 28-03-2018 CFK41_RS16025 6ad6883a2bd3768f541359916f8b5e22 476 Gene3D G3DSA:3.40.50.150 7 244 0.025 T 28-03-2018 CFK41_RS16025 6ad6883a2bd3768f541359916f8b5e22 476 Gene3D G3DSA:3.40.50.150 249 420 2.2E-7 T 28-03-2018 CFK41_RS16025 6ad6883a2bd3768f541359916f8b5e22 476 SUPERFAMILY SSF53335 262 475 3.38E-13 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CFK41_RS12930 1004d3e321f4b2d059c2e4de50168748 168 Pfam PF06305 Lipopolysaccharide assembly protein A domain 105 162 2.5E-11 T 28-03-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 CFK41_RS16700 9698035ae015d7a286244a66dc28e445 427 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 23 421 9.1E-20 T 28-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 CFK41_RS15480 5c5cb0c7dc7a2fa8d9160f93557293a0 140 SUPERFAMILY SSF54593 11 139 9.49E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS15480 5c5cb0c7dc7a2fa8d9160f93557293a0 140 Gene3D G3DSA:3.10.180.10 9 140 4.1E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CFK41_RS10350 f97265621cc4eafd535b833b7b4481ea 42 Pfam PF04030 D-arabinono-1,4-lactone oxidase 2 38 1.6E-4 T 28-03-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 CFK41_RS00230 2186c5c814f2513f6167b72bdc210663 176 Pfam PF03780 Asp23 family, cell envelope-related function 48 158 7.3E-29 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 CFK41_RS11685 f91dac02a1840cddcf41372d92c1b8d3 261 Pfam PF03591 AzlC protein 33 168 2.4E-28 T 28-03-2018 IPR011606 Branched-chain amino acid transport, permease CFK41_RS17655 37bd8e22f3bef0f992a245974f70adb7 469 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 28 384 8.7E-93 T 28-03-2018 IPR003846 Uncharacterised protein family UPF0061 CFK41_RS01975 50e74f2c3fe7a600412bcd4059a9b944 232 Pfam PF04172 LrgB-like family 15 228 2.5E-56 T 28-03-2018 IPR007300 CidB/LrgB family CFK41_RS10090 862d774c3fbbd664da8170ca2a9b192b 610 Pfam PF03023 MviN-like protein 154 543 1.3E-26 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CFK41_RS08165 38d34885668f1a09350b10a2f27f4a01 280 Pfam PF06182 ABC-2 family transporter protein 49 279 8.7E-36 T 28-03-2018 IPR010390 Protein of unknown function DUF990 CFK41_RS03185 e2dc34defa4b3b7b659ebf2565d750a9 96 Gene3D G3DSA:1.10.10.10 4 94 7.4E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CFK41_RS06065 4db1f9c27af3b0a97063a388f842f39d 478 Pfam PF01566 Natural resistance-associated macrophage protein 68 440 7.6E-10 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CFK41_RS10910 d5e1c02ebd6aa224fc6b688a5f91c32b 215 Gene3D G3DSA:3.40.190.10 1 211 1.0E-5 T 28-03-2018 CFK41_RS06515 b61a3c436e4a21c62d090ddc80495f7a 182 Gene3D G3DSA:1.25.40.10 12 181 1.7E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CFK41_RS13120 4a64ae6b9e53f818a71edf776df6be41 104 Pfam PF11662 Protein of unknown function (DUF3263) 23 89 2.1E-25 T 28-03-2018 IPR021678 Protein of unknown function DUF3263 CFK41_RS09680 c209d9edf00325cb3f8837de58cc14f1 273 Pfam PF12502 Protein of unknown function (DUF3710) 77 248 5.2E-58 T 28-03-2018 IPR022183 Protein of unknown function DUF3710 CFK41_RS12425 d63780ae0a49f570c97844f1ead9d48f 66 Pfam PF11273 Protein of unknown function (DUF3073) 2 57 2.2E-21 T 28-03-2018 IPR021426 Protein of unknown function DUF3073 CFK41_RS15285 55782c774f537f23575f6f41c733efd7 144 Pfam PF06923 Glucitol operon activator protein (GutM) 6 103 9.8E-14 T 28-03-2018 IPR009693 Glucitol operon activator CFK41_RS15195 b6f5ff92b6fe0f58e5e10d181b1c6d55 383 Pfam PF05684 Protein of unknown function (DUF819) 10 382 1.8E-97 T 28-03-2018 IPR008537 Protein of unknown function DUF819 CFK41_RS04365 50f74ad979cc8afea28bce239419db1a 164 Pfam PF14012 Protein of unknown function (DUF4229) 5 66 7.3E-11 T 28-03-2018 IPR025323 Protein of unknown function DUF4229 CFK41_RS04260 07839d32b6c8b370fe642866e6b13e61 67 Pfam PF14013 MT0933-like antitoxin protein 8 53 1.3E-12 T 28-03-2018 IPR028037 Antitoxin Rv0909/MT0933 CFK41_RS09700 42cd76f7be158ef65e77b3ba9ddb73b7 449 Pfam PF11268 Protein of unknown function (DUF3071) 1 161 5.9E-47 T 28-03-2018 IPR021421 Protein of unknown function DUF3071 CFK41_RS01505 d229ad3889b9fc62f1e9fd9588c12cfa 220 Pfam PF04854 Protein of unknown function, DUF624 22 90 4.4E-10 T 28-03-2018 IPR006938 Protein of unknown function DUF624 CFK41_RS06155 b51b4671a2a7d216ea8dbcbd44b05c69 278 Pfam PF01061 ABC-2 type transporter 34 236 3.2E-10 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CFK41_RS15405 5a821b964e45378e48affb1bfca20928 329 Pfam PF01758 Sodium Bile acid symporter family 56 234 2.5E-42 T 28-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 CFK41_RS13445 5b02e614b3628ac71a37acc605d29fe4 266 Pfam PF07920 Protein of unknown function (DUF1684) 131 259 9.1E-28 T 28-03-2018 IPR012467 Protein of unknown function DUF1684 CFK41_RS07465 d1932327af57e1f0e64cfcdb9041dc2c 193 Pfam PF02620 Uncharacterized ACR, COG1399 72 180 3.8E-26 T 28-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD CFK41_RS05010 89d8dbcaa985ccdfcba11db8317e9867 251 Pfam PF14030 Protein of unknown function (DUF4245) 70 240 2.8E-36 T 28-03-2018 IPR025339 Protein of unknown function DUF4245 CFK41_RS00980 39bc84ec3b0709231dbe156b078d8ef2 162 Gene3D G3DSA:3.40.190.10 2 145 3.7E-4 T 28-03-2018 CFK41_RS16170 d8f477569cd45c7b3e424720087cdde9 384 Pfam PF06224 Winged helix DNA-binding domain 32 378 8.9E-33 T 28-03-2018 IPR009351 Protein of unknown function DUF1006 CFK41_RS07820 dd20f7e39fe0dc4f1af9619afb32fdb5 237 Pfam PF04854 Protein of unknown function, DUF624 29 114 5.4E-15 T 28-03-2018 IPR006938 Protein of unknown function DUF624 CFK41_RS02970 287a10cfe7e87698f364a594c13c73fe 246 Pfam PF05949 Bacterial protein of unknown function (DUF881) 94 239 4.9E-33 T 28-03-2018 IPR010273 Protein of unknown function DUF881 CFK41_RS16440 988034a743ee78306ccd060f3e12f96a 231 Pfam PF04854 Protein of unknown function, DUF624 37 114 7.5E-6 T 28-03-2018 IPR006938 Protein of unknown function DUF624 CFK41_RS00685 c61dbad7db7eb3477efb62101f5732fc 474 Pfam PF07670 Nucleoside recognition 163 258 1.2E-8 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CFK41_RS17630 b1c758e167070fe9276d53690fbeddc7 543 Gene3D G3DSA:3.40.1800.10 373 454 1.1E-6 T 28-03-2018 CFK41_RS13275 02cee063ec20528c32dcf7d4a6553efd 368 Pfam PF09949 Uncharacterized conserved protein (DUF2183) 223 319 1.1E-31 T 28-03-2018 IPR019236 Domain of unknown function DUF2183 CFK41_RS06595 7ce6f61656df53edb85b04d1b5759cfe 123 Pfam PF11238 Protein of unknown function (DUF3039) 40 94 1.2E-31 T 28-03-2018 IPR021400 Protein of unknown function DUF3039 CFK41_RS13775 d80013b150c57a5868943e0c7f7b12c9 157 Pfam PF09350 Domain of unknown function (DUF1992) 8 75 2.9E-17 T 28-03-2018 IPR018961 DnaJ homologue, subfamily C, member 28, conserved domain CFK41_RS07750 d547cc046d5226c552c4d8482fe73b9d 469 Pfam PF11299 Protein of unknown function (DUF3100) 34 273 4.4E-81 T 28-03-2018 IPR021450 Protein of unknown function DUF3100 CFK41_RS06900 81edcd4d344d423241a3d5364cc8e091 111 Pfam PF13490 Putative zinc-finger 22 48 4.0E-6 T 28-03-2018 IPR027383 Putative zinc-finger CFK41_RS04740 ac0a493f076895f222df6576887aad29 384 Pfam PF04230 Polysaccharide pyruvyl transferase 42 325 2.5E-12 T 28-03-2018 IPR007345 Polysaccharide pyruvyl transferase CFK41_RS11245 28166c818e3e7bebc8f6e076e4173300 73 Pfam PF11305 Protein of unknown function (DUF3107) 1 71 5.3E-27 T 28-03-2018 IPR021456 Protein of unknown function DUF3107 CFK41_RS01960 0d6890848ec2abdaafbebc586950963a 216 Gene3D G3DSA:3.90.70.10 53 216 2.9E-10 T 28-03-2018 CFK41_RS02725 3ded756489cb4933c139e99ab9f586ae 253 Pfam PF04854 Protein of unknown function, DUF624 26 92 2.2E-9 T 28-03-2018 IPR006938 Protein of unknown function DUF624 CFK41_RS09300 fa876a9beaf0cce0088237844b2546b0 305 Pfam PF03458 UPF0126 domain 24 97 5.7E-12 T 28-03-2018 IPR005115 Uncharacterised domain UPF0126 CFK41_RS09300 fa876a9beaf0cce0088237844b2546b0 305 Pfam PF03458 UPF0126 domain 110 183 2.4E-15 T 28-03-2018 IPR005115 Uncharacterised domain UPF0126