locus-tag	class	description
AXW76_RS00200	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AXW76_RS00240	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AXW76_RS00345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXW76_RS00405	COG0500	methyltransferase
AXW76_RS00440	COG0463	Glycosyl transferase, family 2
AXW76_RS00710	COG3383	formate dehydrogenase (NAD+) activity
AXW76_RS00710	COG0243	molybdopterin cofactor binding
AXW76_RS01020	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AXW76_RS01045	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AXW76_RS01085	COG1733	regulation of RNA biosynthetic process
AXW76_RS01100	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS01110	COG4584	PFAM Integrase catalytic
AXW76_RS01115	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS01120	COG3181	Tripartite tricarboxylate transporter family receptor
AXW76_RS01125	COG0203	ribosomal protein L17
AXW76_RS01130	COG0202	RNA polymerase activity
AXW76_RS01135	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AXW76_RS01140	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AXW76_RS01145	COG0563	adenylate kinase activity
AXW76_RS01155	COG0200	Binds to the 23S rRNA
AXW76_RS01160	COG1841	ribosomal large subunit assembly
AXW76_RS01165	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AXW76_RS01170	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AXW76_RS01175	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AXW76_RS01180	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AXW76_RS01185	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AXW76_RS01190	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AXW76_RS01195	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AXW76_RS01200	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AXW76_RS01205	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AXW76_RS01210	COG0255	Belongs to the universal ribosomal protein uL29 family
AXW76_RS01215	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AXW76_RS01220	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AXW76_RS01225	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AXW76_RS01230	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AXW76_RS01235	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AXW76_RS01240	COG0089	rRNA binding
AXW76_RS01245	COG0088	Forms part of the polypeptide exit tunnel
AXW76_RS01250	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AXW76_RS01255	COG0051	transcription antitermination factor activity, RNA binding
AXW76_RS01260	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AXW76_RS01265	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AXW76_RS01270	COG0049	tRNA binding
AXW76_RS01275	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AXW76_RS01290	COG1231	oxidoreductase activity
AXW76_RS01295	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AXW76_RS01300	COG0085	RNA polymerase activity
AXW76_RS01305	COG0222	ribosome binding
AXW76_RS01310	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AXW76_RS01315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AXW76_RS01320	COG0081	regulation of translation
AXW76_RS01325	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AXW76_RS01330	COG0250	Participates in transcription elongation, termination and antitermination
AXW76_RS01335	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AXW76_RS01355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXW76_RS01360	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AXW76_RS01360	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AXW76_RS01365	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AXW76_RS01390	COG3959	Transketolase, thiamine diphosphate binding domain
AXW76_RS01395	COG3958	Transketolase
AXW76_RS01420	COG2226	methyltransferase
AXW76_RS01440	COG0673	inositol 2-dehydrogenase activity
AXW76_RS01475	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS01485	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS01515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AXW76_RS01520	COG1280	lysine exporter protein (LysE YggA)
AXW76_RS01530	COG1960	acyl-CoA dehydrogenase activity
AXW76_RS01550	COG3246	L-lysine catabolic process to acetate
AXW76_RS01555	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXW76_RS01565	COG3246	L-lysine catabolic process to acetate
AXW76_RS01585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXW76_RS01605	COG2274	protein secretion by the type I secretion system
AXW76_RS01650	COG0437	4 iron, 4 sulfur cluster binding
AXW76_RS01720	COG0784	Response regulator, receiver
AXW76_RS01720	COG4191	Histidine kinase
AXW76_RS01740	COG3795	YCII-related domain
AXW76_RS01750	COG0210	DNA helicase
AXW76_RS01755	COG0402	S-adenosylhomocysteine deaminase activity
AXW76_RS01765	COG0477	Major facilitator Superfamily
AXW76_RS01785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AXW76_RS01805	COG2801	Transposase and inactivated derivatives
AXW76_RS01865	COG2801	Transposase and inactivated derivatives
AXW76_RS01955	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AXW76_RS01980	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AXW76_RS01985	COG0302	gtp cyclohydrolase
AXW76_RS02000	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AXW76_RS02020	COG0477	Major facilitator Superfamily
AXW76_RS02060	COG2814	Major facilitator Superfamily
AXW76_RS02065	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AXW76_RS02070	COG5295	Hep Hag repeat protein
AXW76_RS02090	COG5001	Diguanylate cyclase
AXW76_RS02095	COG2801	Transposase and inactivated derivatives
AXW76_RS02110	COG4221	oxidoreductase activity
AXW76_RS02110	COG3321	synthase
AXW76_RS02110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AXW76_RS02110	COG0604	alcohol dehydrogenase
AXW76_RS02120	COG0667	Aldo Keto reductase
AXW76_RS02135	COG1752	Esterase of the alpha-beta hydrolase superfamily
AXW76_RS02140	COG0517	IMP dehydrogenase activity
AXW76_RS02160	COG3920	Histidine kinase
AXW76_RS02185	COG2261	transglycosylase associated protein
AXW76_RS02295	COG4584	PFAM Integrase catalytic
AXW76_RS02305	COG2801	Transposase and inactivated derivatives
AXW76_RS02335	COG1278	Cold shock
AXW76_RS02430	COG0513	Belongs to the DEAD box helicase family
AXW76_RS02450	COG1063	alcohol dehydrogenase
AXW76_RS02480	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AXW76_RS02495	COG3842	ATPase activity
AXW76_RS02505	COG1176	ABC-type spermidine putrescine transport system, permease component I
AXW76_RS02570	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXW76_RS02585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXW76_RS02605	COG2814	Major facilitator Superfamily
AXW76_RS02615	COG0747	negative chemotaxis
AXW76_RS02625	COG0601	transmembrane transport
AXW76_RS02630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW76_RS02635	COG4172	Belongs to the ABC transporter superfamily
AXW76_RS02645	COG1473	amidohydrolase
AXW76_RS02650	COG0154	amidase activity
AXW76_RS02655	COG1024	Enoyl-CoA hydratase
AXW76_RS02670	COG0625	glutathione transferase activity
AXW76_RS02685	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AXW76_RS02690	COG1546	Belongs to the CinA family
AXW76_RS02690	COG1058	Belongs to the CinA family
AXW76_RS02695	COG2308	Evidence 4 Homologs of previously reported genes of
AXW76_RS02725	COG4221	oxidoreductase activity
AXW76_RS02740	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AXW76_RS02755	COG5425	PFAM Usg family protein
AXW76_RS02760	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AXW76_RS02765	COG0459	protein refolding
AXW76_RS02805	COG1335	isochorismatase
AXW76_RS02875	COG0384	phenazine biosynthesis protein PhzF
AXW76_RS02885	COG2814	Major facilitator Superfamily
AXW76_RS02890	COG2188	Transcriptional regulator
AXW76_RS02905	COG0842	Transport permease protein
AXW76_RS02910	COG1131	(ABC) transporter
AXW76_RS02925	COG0640	Transcriptional regulator
AXW76_RS02965	COG3608	succinylglutamate desuccinylase aspartoacylase
AXW76_RS02965	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AXW76_RS03000	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AXW76_RS03005	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXW76_RS03010	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AXW76_RS03050	COG2204	response regulator
AXW76_RS03055	COG0784	Response regulator, receiver
AXW76_RS03055	COG4191	Histidine kinase
AXW76_RS03085	COG2815	serine threonine protein kinase
AXW76_RS03085	COG0515	serine threonine protein kinase
AXW76_RS03115	COG2197	response regulator
AXW76_RS03125	COG1309	transcriptional regulator
AXW76_RS03130	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AXW76_RS03165	COG0318	PFAM AMP-dependent synthetase and ligase
AXW76_RS03170	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AXW76_RS03210	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AXW76_RS03230	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AXW76_RS03235	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AXW76_RS03240	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AXW76_RS03245	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AXW76_RS03275	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AXW76_RS03295	COG0047	phosphoribosylformylglycinamidine synthase activity
AXW76_RS03305	COG0598	Magnesium transport protein CorA
AXW76_RS03310	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AXW76_RS03315	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AXW76_RS03325	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AXW76_RS03330	COG1116	anion transmembrane transporter activity
AXW76_RS03330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXW76_RS03335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW76_RS03340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXW76_RS03350	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AXW76_RS03365	COG1309	transcriptional regulator
AXW76_RS03375	COG2020	methyltransferase activity
AXW76_RS03400	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AXW76_RS03405	COG0538	isocitrate dehydrogenase activity
AXW76_RS03415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AXW76_RS03420	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AXW76_RS03425	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AXW76_RS03430	COG0509	glycine decarboxylation via glycine cleavage system
AXW76_RS03435	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AXW76_RS03435	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AXW76_RS03445	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AXW76_RS03550	COG0640	Transcriptional regulator
AXW76_RS03555	COG0446	pyridine nucleotide-disulphide oxidoreductase
AXW76_RS03595	COG1879	ABC-type sugar transport system periplasmic component
AXW76_RS03600	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXW76_RS03610	COG1070	Carbohydrate kinase
AXW76_RS03660	COG2917	probably involved in intracellular septation
AXW76_RS03675	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AXW76_RS03675	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AXW76_RS03700	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXW76_RS03705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW76_RS03730	COG4584	PFAM Integrase catalytic
AXW76_RS03750	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AXW76_RS03755	COG1684	flagellar biosynthetic protein fliR
AXW76_RS03760	COG1987	bacterial-type flagellum assembly
AXW76_RS03765	COG1677	Flagellar hook-basal body complex protein FliE
AXW76_RS03770	COG1558	bacterial-type flagellum-dependent cell motility
AXW76_RS03785	COG1338	Plays a role in the flagellum-specific transport system
AXW76_RS03835	COG4786	Flagellar basal body rod
AXW76_RS03840	COG4786	Flagellar basal body rod
AXW76_RS03850	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AXW76_RS03855	COG3971	2-oxopent-4-enoate hydratase activity
AXW76_RS03860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXW76_RS03865	COG1733	regulation of RNA biosynthetic process
AXW76_RS03875	COG2910	NAD(P)H-binding
AXW76_RS03880	COG1733	regulation of RNA biosynthetic process
AXW76_RS03890	COG1706	bacterial-type flagellum-dependent cell motility
AXW76_RS03910	COG5442	Flagellar protein FlaF
AXW76_RS03915	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AXW76_RS03920	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AXW76_RS03925	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AXW76_RS03930	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AXW76_RS03935	COG5443	negative regulation of bacterial-type flagellum assembly
AXW76_RS03940	COG0076	glutamate decarboxylase activity
AXW76_RS03965	COG1256	bacterial-type flagellum assembly
AXW76_RS03985	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXW76_RS04010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXW76_RS04030	COG3300	MHYT domain
AXW76_RS04030	COG5001	Diguanylate cyclase
AXW76_RS04040	COG3685	Protein conserved in bacteria
AXW76_RS04055	COG2271	Major facilitator Superfamily
AXW76_RS04060	COG0583	DNA-binding transcription factor activity
AXW76_RS04065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXW76_RS04075	COG1012	belongs to the aldehyde dehydrogenase family
AXW76_RS04080	COG2721	sulfolactate sulfo-lyase activity
AXW76_RS04095	COG0745	RESPONSE REGULATOR receiver
AXW76_RS04125	COG0492	ferredoxin-NADP+ reductase activity
AXW76_RS04135	COG0633	Ferredoxin
AXW76_RS04165	COG3218	ABC-type transport auxiliary lipoprotein component
AXW76_RS04165	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AXW76_RS04170	COG1127	ABC transporter
AXW76_RS04175	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AXW76_RS04180	COG4948	Mandelate Racemase Muconate Lactonizing
AXW76_RS04185	COG2814	Major facilitator Superfamily
AXW76_RS04200	COG4154	Belongs to the RbsD FucU family
AXW76_RS04230	COG0351	phosphomethylpyrimidine kinase
AXW76_RS04235	COG4191	Histidine kinase
AXW76_RS04235	COG0784	Response regulator, receiver
AXW76_RS04250	COG2010	Cytochrome c
AXW76_RS04270	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AXW76_RS04275	COG3909	cytochrome
AXW76_RS04305	COG0673	inositol 2-dehydrogenase activity
AXW76_RS04310	COG0662	Cupin 2, conserved barrel domain protein
AXW76_RS04310	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AXW76_RS04325	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AXW76_RS04345	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AXW76_RS04345	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AXW76_RS04355	COG0859	PFAM glycosyl transferase family 9
AXW76_RS04370	COG1132	(ABC) transporter
AXW76_RS04390	COG0583	DNA-binding transcription factor activity
AXW76_RS04395	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS04400	COG1942	4-Oxalocrotonate Tautomerase
AXW76_RS04415	COG0489	protein tyrosine kinase activity
AXW76_RS04430	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AXW76_RS04435	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AXW76_RS04450	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AXW76_RS04520	COG0318	PFAM AMP-dependent synthetase and ligase
AXW76_RS04525	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXW76_RS04545	COG2942	2-epimerase
AXW76_RS04555	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AXW76_RS04570	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AXW76_RS04570	COG0662	Cupin 2, conserved barrel domain protein
AXW76_RS04590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXW76_RS04610	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AXW76_RS04630	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AXW76_RS04635	COG1216	Glycosyl transferase, family 2
AXW76_RS04635	COG0438	transferase activity, transferring glycosyl groups
AXW76_RS04660	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AXW76_RS04695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXW76_RS04710	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXW76_RS04725	COG3181	Tripartite tricarboxylate transporter family receptor
AXW76_RS04740	COG1024	Enoyl-CoA hydratase
AXW76_RS04745	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AXW76_RS04755	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AXW76_RS04760	COG1802	Transcriptional regulator
AXW76_RS04825	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AXW76_RS04895	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AXW76_RS04905	COG3181	Tripartite tricarboxylate transporter family receptor
AXW76_RS04910	COG2080	2 iron, 2 sulfur cluster binding
AXW76_RS04925	COG0516	GMP reductase activity
AXW76_RS04925	COG0517	IMP dehydrogenase activity
AXW76_RS04940	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS04955	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXW76_RS04960	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AXW76_RS04970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AXW76_RS04975	COG2010	Cytochrome c
AXW76_RS04980	COG3218	ABC-type transport auxiliary lipoprotein component
AXW76_RS04980	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AXW76_RS04985	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AXW76_RS05005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXW76_RS05005	COG1042	CoA-binding domain protein
AXW76_RS05005	COG0045	succinate-CoA ligase (ADP-forming) activity
AXW76_RS05030	COG3243	poly(R)-hydroxyalkanoic acid synthase
AXW76_RS05035	COG0517	IMP dehydrogenase activity
AXW76_RS05035	COG0617	tRNA 3'-terminal CCA addition
AXW76_RS05035	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AXW76_RS05040	COG0251	oxidation-reduction process
AXW76_RS05070	COG1024	Enoyl-CoA hydratase
AXW76_RS05075	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS05085	COG1960	acyl-CoA dehydrogenase activity
AXW76_RS05090	COG0318	PFAM AMP-dependent synthetase and ligase
AXW76_RS05100	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXW76_RS05110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW76_RS05115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW76_RS05125	COG0129	dihydroxy-acid dehydratase activity
AXW76_RS05170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXW76_RS05185	COG2816	NAD+ diphosphatase activity
AXW76_RS05190	COG4608	Belongs to the ABC transporter superfamily
AXW76_RS05195	COG0444	Belongs to the ABC transporter superfamily
AXW76_RS05200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW76_RS05205	COG0601	transmembrane transport
AXW76_RS05210	COG0747	negative chemotaxis
AXW76_RS05255	COG1672	PFAM Archaeal ATPase
AXW76_RS05255	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AXW76_RS05295	COG4372	Transposase
AXW76_RS05305	COG2801	Transposase and inactivated derivatives
AXW76_RS05315	COG1408	metallophosphoesterase
AXW76_RS05330	COG3547	Transposase (IS116 IS110 IS902 family)
AXW76_RS05355	COG3415	Transposase
AXW76_RS05355	COG2801	Transposase and inactivated derivatives
AXW76_RS05405	COG4948	Mandelate Racemase Muconate Lactonizing
AXW76_RS05415	COG3258	Cytochrome c
AXW76_RS05425	COG0010	Belongs to the arginase family
AXW76_RS05435	COG3706	GGDEF domain
AXW76_RS05435	COG5001	Diguanylate cyclase
AXW76_RS05435	COG2203	Gaf domain
AXW76_RS05435	COG4251	negative regulation of phosphorylation
AXW76_RS05455	COG2010	Cytochrome c
AXW76_RS05530	COG2252	PERMEase
AXW76_RS05535	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AXW76_RS05545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AXW76_RS05550	COG1301	dicarboxylic acid transport
AXW76_RS05570	COG1079	Belongs to the binding-protein-dependent transport system permease family
AXW76_RS05575	COG1079	Belongs to the binding-protein-dependent transport system permease family
AXW76_RS05585	COG3845	ABC transporter
AXW76_RS05600	COG3845	ABC transporter
AXW76_RS05605	COG4603	Belongs to the binding-protein-dependent transport system permease family
AXW76_RS05610	COG1079	Belongs to the binding-protein-dependent transport system permease family
AXW76_RS05630	COG2080	2 iron, 2 sulfur cluster binding
AXW76_RS05630	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AXW76_RS05635	COG2233	PERMEase
AXW76_RS05680	COG0235	Class ii aldolase
AXW76_RS05685	COG2095	MarC family integral membrane protein
AXW76_RS05700	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AXW76_RS05705	COG0776	regulation of translation
AXW76_RS05710	COG0183	Belongs to the thiolase family
AXW76_RS05760	COG2197	response regulator
AXW76_RS05765	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AXW76_RS05785	COG1131	(ABC) transporter
AXW76_RS05920	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AXW76_RS05925	COG3791	Glutathione-dependent formaldehyde-activating
AXW76_RS05945	COG0723	plastoquinol--plastocyanin reductase activity
AXW76_RS05955	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXW76_RS05960	COG0277	FAD linked oxidase domain protein
AXW76_RS05965	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AXW76_RS05995	COG3300	MHYT domain
AXW76_RS05995	COG5001	Diguanylate cyclase
AXW76_RS06040	COG1309	transcriptional regulator
AXW76_RS06045	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AXW76_RS06050	COG2986	histidine ammonia-lyase
AXW76_RS06055	COG1228	amidohydrolase
AXW76_RS06060	COG1228	amidohydrolase
AXW76_RS06075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW76_RS06080	COG1116	anion transmembrane transporter activity
AXW76_RS06090	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AXW76_RS06100	COG1917	Cupin 2, conserved barrel domain protein
AXW76_RS06100	COG4977	sequence-specific DNA binding
AXW76_RS06105	COG2223	nitrite transmembrane transporter activity
AXW76_RS06120	COG0656	L-ascorbic acid biosynthetic process
AXW76_RS06130	COG1566	PFAM secretion protein HlyD family protein
AXW76_RS06140	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXW76_RS06150	COG1764	response to oxidative stress
AXW76_RS06160	COG0596	Alpha beta hydrolase
AXW76_RS06200	COG2267	carboxylic ester hydrolase activity
AXW76_RS06205	COG2169	Transcriptional regulator
AXW76_RS06215	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AXW76_RS06235	COG1802	Transcriptional regulator
AXW76_RS06240	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AXW76_RS06255	COG2873	o-acetylhomoserine
AXW76_RS06260	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AXW76_RS06275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AXW76_RS06280	COG0318	PFAM AMP-dependent synthetase and ligase
AXW76_RS06295	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS06305	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AXW76_RS06315	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AXW76_RS06355	COG3344	reverse transcriptase
AXW76_RS06360	COG2197	response regulator
AXW76_RS06365	COG2197	response regulator
AXW76_RS06380	COG2963	transposase activity
AXW76_RS06385	COG3436	PFAM IS66 Orf2 family protein
AXW76_RS06390	COG2433	Pfam Transposase IS66
AXW76_RS06435	COG2801	Transposase and inactivated derivatives
AXW76_RS06440	COG3436	PFAM IS66 Orf2 family protein
AXW76_RS06445	COG4372	Transposase
AXW76_RS06450	COG2963	transposase activity
AXW76_RS06455	COG3436	PFAM IS66 Orf2 family protein
AXW76_RS06475	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXW76_RS06480	COG4372	Transposase
AXW76_RS06490	COG4372	Transposase
AXW76_RS06495	COG4372	Transposase
AXW76_RS06525	COG0463	Glycosyl transferase, family 2
AXW76_RS06545	COG0367	asparagine synthase
AXW76_RS06555	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AXW76_RS06570	COG2801	Transposase and inactivated derivatives
AXW76_RS06625	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AXW76_RS06630	COG1596	polysaccharide export
AXW76_RS06635	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AXW76_RS06685	COG2084	Dehydrogenase
AXW76_RS06695	COG1129	ABC transporter
AXW76_RS06715	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXW76_RS06725	COG1522	sequence-specific DNA binding
AXW76_RS06770	COG0651	ATP synthesis coupled electron transport
AXW76_RS06785	COG0651	ATP synthesis coupled electron transport
AXW76_RS06790	COG0649	NAD binding
AXW76_RS06795	COG3260	NADH ubiquinone oxidoreductase 20
AXW76_RS06835	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AXW76_RS06850	COG1181	Belongs to the D-alanine--D-alanine ligase family
AXW76_RS06890	COG0673	inositol 2-dehydrogenase activity
AXW76_RS06895	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AXW76_RS06905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXW76_RS06910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXW76_RS06920	COG1116	anion transmembrane transporter activity
AXW76_RS06935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXW76_RS06945	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AXW76_RS06950	COG0297	glycogen (starch) synthase activity
AXW76_RS06960	COG4095	Psort location CytoplasmicMembrane, score
AXW76_RS06990	COG2072	flavoprotein involved in K transport
AXW76_RS07010	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AXW76_RS07015	COG0281	malic enzyme
AXW76_RS07025	COG0668	transmembrane transport
AXW76_RS07040	COG2326	polyphosphate kinase activity
AXW76_RS07105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW76_RS07115	COG1125	glycine betaine transport
AXW76_RS07115	COG0517	IMP dehydrogenase activity
AXW76_RS07120	COG1174	glycine betaine transport
AXW76_RS07145	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS07155	COG3300	MHYT domain
AXW76_RS07155	COG5001	Diguanylate cyclase
AXW76_RS07160	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AXW76_RS07180	COG0440	acetolactate synthase activity
AXW76_RS07190	COG0028	Belongs to the TPP enzyme family
AXW76_RS07195	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AXW76_RS07215	COG0330	HflC and HflK could
AXW76_RS07220	COG0330	HflC and HflK could
AXW76_RS07235	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AXW76_RS07275	COG0114	fumarate hydratase activity
AXW76_RS07365	COG1309	transcriptional regulator
AXW76_RS07440	COG2200	EAL domain
AXW76_RS07440	COG2199	diguanylate cyclase activity
AXW76_RS07440	COG2202	Pas domain
AXW76_RS07445	COG2271	Major facilitator Superfamily
AXW76_RS07450	COG3300	MHYT domain
AXW76_RS07450	COG5001	Diguanylate cyclase
AXW76_RS07460	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXW76_RS07465	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXW76_RS07470	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXW76_RS07475	COG2259	Doxx family
AXW76_RS07480	COG0583	DNA-binding transcription factor activity
AXW76_RS07505	COG0277	FAD linked oxidase domain protein
AXW76_RS07515	COG5487	UPF0391 membrane protein
AXW76_RS07520	COG0210	DNA helicase
AXW76_RS07540	COG1088	dTDP-glucose 4,6-dehydratase activity
AXW76_RS07555	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AXW76_RS07575	COG0071	Belongs to the small heat shock protein (HSP20) family
AXW76_RS07600	COG2267	carboxylic ester hydrolase activity
AXW76_RS07610	COG1131	(ABC) transporter
AXW76_RS07615	COG0842	Transport permease protein
AXW76_RS07635	COG0584	glycerophosphoryl diester phosphodiesterase
AXW76_RS07660	COG2264	protein methyltransferase activity
AXW76_RS07670	COG0006	proline dipeptidase activity
AXW76_RS07670	COG0006	proline dipeptidase activity
AXW76_RS07675	COG2814	Major facilitator Superfamily
AXW76_RS07680	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AXW76_RS07705	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AXW76_RS07710	COG0849	cell division
AXW76_RS07715	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AXW76_RS07720	COG1181	Belongs to the D-alanine--D-alanine ligase family
AXW76_RS07730	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AXW76_RS07735	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AXW76_RS07745	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AXW76_RS07750	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AXW76_RS07755	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AXW76_RS07760	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AXW76_RS07775	COG0275	rRNA processing
AXW76_RS07780	COG3023	N-Acetylmuramoyl-L-alanine amidase
AXW76_RS07790	COG4941	Belongs to the sigma-70 factor family
AXW76_RS07795	COG3795	YCII-related domain
AXW76_RS07815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXW76_RS07835	COG5265	(ABC) transporter
AXW76_RS07850	COG1309	transcriptional regulator
AXW76_RS07890	COG0688	phosphatidylethanolamine metabolic process
AXW76_RS07910	COG0438	transferase activity, transferring glycosyl groups
AXW76_RS07915	COG1388	LysM domain
AXW76_RS07915	COG1376	ErfK ybiS ycfS ynhG family protein
AXW76_RS07920	COG3474	cytochrome
AXW76_RS07925	COG2827	Endonuclease containing a URI domain
AXW76_RS07965	COG3842	ATPase activity
AXW76_RS07975	COG1176	ABC-type spermidine putrescine transport system, permease component I
AXW76_RS08030	COG2022	thiamine diphosphate biosynthetic process
AXW76_RS08040	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AXW76_RS08065	COG0625	glutathione transferase activity
AXW76_RS08115	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS08120	COG2204	response regulator
AXW76_RS08145	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXW76_RS08160	COG2193	ferroxidase activity
AXW76_RS08200	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXW76_RS08220	COG2897	thiosulfate sulfurtransferase activity
AXW76_RS08225	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AXW76_RS08240	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AXW76_RS08265	COG3708	Transcriptional regulator
AXW76_RS08265	COG2207	Transcriptional regulator
AXW76_RS08270	COG4948	Mandelate Racemase Muconate Lactonizing
AXW76_RS08310	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AXW76_RS08310	COG1672	PFAM Archaeal ATPase
AXW76_RS08325	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXW76_RS08330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXW76_RS08335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW76_RS08340	COG0601	transmembrane transport
AXW76_RS08345	COG0747	negative chemotaxis
AXW76_RS08355	COG0784	Response regulator, receiver
AXW76_RS08355	COG4191	Histidine kinase
AXW76_RS08370	COG1231	oxidoreductase activity
AXW76_RS08415	COG2207	Transcriptional regulator
AXW76_RS08425	COG4948	Mandelate Racemase Muconate Lactonizing
AXW76_RS08435	COG0386	Belongs to the glutathione peroxidase family
AXW76_RS08440	COG0154	amidase activity
AXW76_RS08455	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AXW76_RS08460	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AXW76_RS08465	COG0535	radical SAM domain protein
AXW76_RS08470	COG0535	radical SAM domain protein
AXW76_RS08485	COG0493	'glutamate synthase
AXW76_RS08490	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AXW76_RS08490	COG0674	pyruvate-flavodoxin oxidoreductase activity
AXW76_RS08495	COG1013	pyruvate-flavodoxin oxidoreductase activity
AXW76_RS08545	COG2719	SpoVR family
AXW76_RS08550	COG2718	Belongs to the UPF0229 family
AXW76_RS08555	COG2766	serine protein kinase
AXW76_RS08570	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AXW76_RS08575	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AXW76_RS08580	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AXW76_RS08585	COG0363	glucosamine-6-phosphate deaminase activity
AXW76_RS08590	COG3265	gluconokinase activity
AXW76_RS08600	COG3387	PFAM Glycoside hydrolase 15-related
AXW76_RS08605	COG1640	4-alpha-glucanotransferase
AXW76_RS08610	COG0366	Alpha amylase catalytic
AXW76_RS08615	COG0366	Alpha amylase catalytic
AXW76_RS08620	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AXW76_RS08630	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AXW76_RS08650	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AXW76_RS08655	COG0745	RESPONSE REGULATOR receiver
AXW76_RS08660	COG2205	protein histidine kinase activity
AXW76_RS08670	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AXW76_RS08675	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AXW76_RS08680	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AXW76_RS08705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXW76_RS08725	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AXW76_RS08730	COG0318	PFAM AMP-dependent synthetase and ligase
AXW76_RS08770	COG2030	dehydratase
AXW76_RS08805	COG0477	Major facilitator Superfamily
AXW76_RS08820	COG1053	succinate dehydrogenase
AXW76_RS08825	COG1414	Transcriptional regulator
AXW76_RS08830	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS08835	COG0028	Belongs to the TPP enzyme family
AXW76_RS08835	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
AXW76_RS08865	COG0028	Belongs to the TPP enzyme family
AXW76_RS08870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AXW76_RS08890	COG2272	Belongs to the type-B carboxylesterase lipase family
AXW76_RS08895	COG0477	Major facilitator Superfamily
AXW76_RS08900	COG1309	transcriptional regulator
AXW76_RS08910	COG1176	ABC-type spermidine putrescine transport system, permease component I
AXW76_RS08920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXW76_RS08930	COG3842	ATPase activity
AXW76_RS08935	COG0583	DNA-binding transcription factor activity
AXW76_RS08945	COG1063	alcohol dehydrogenase
AXW76_RS08950	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXW76_RS08960	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXW76_RS08970	COG0246	Mannitol dehydrogenase
AXW76_RS08995	COG0412	Dienelactone hydrolase
AXW76_RS09050	COG0411	ABC transporter
AXW76_RS09055	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXW76_RS09060	COG0683	leucine binding
AXW76_RS09075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXW76_RS09080	COG1464	Belongs to the NlpA lipoprotein family
AXW76_RS09090	COG1309	transcriptional regulator
AXW76_RS09095	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXW76_RS09125	COG1126	abc transporter atp-binding protein
AXW76_RS09135	COG0765	amino acid transport
AXW76_RS09145	COG0673	inositol 2-dehydrogenase activity
AXW76_RS09165	COG1595	DNA-templated transcription, initiation
AXW76_RS09175	COG0477	Major facilitator Superfamily
AXW76_RS09190	COG4191	Histidine kinase
AXW76_RS09190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW76_RS09195	COG2204	response regulator
AXW76_RS09200	COG1024	Enoyl-CoA hydratase
AXW76_RS09200	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AXW76_RS09205	COG0309	Hydrogenase expression formation protein (HypE)
AXW76_RS09210	COG0409	Hydrogenase expression formation protein
AXW76_RS09225	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AXW76_RS09230	COG0375	protein maturation
AXW76_RS09235	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AXW76_RS09240	COG1773	rubredoxin
AXW76_RS09245	COG1773	rubredoxin
AXW76_RS09250	COG1773	rubredoxin
AXW76_RS09255	COG3118	belongs to the thioredoxin family
AXW76_RS09260	COG0298	carbon dioxide binding
AXW76_RS09265	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AXW76_RS09270	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
AXW76_RS09275	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AXW76_RS09320	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AXW76_RS09330	COG4584	PFAM Integrase catalytic
AXW76_RS09360	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXW76_RS09365	COG4372	Transposase
AXW76_RS09375	COG2801	Transposase and inactivated derivatives
AXW76_RS09430	COG0459	protein refolding
AXW76_RS09435	COG3344	reverse transcriptase
AXW76_RS09530	COG2801	Transposase and inactivated derivatives
AXW76_RS09570	COG4191	Histidine kinase
AXW76_RS09595	COG1335	isochorismatase
AXW76_RS09630	COG2197	response regulator
AXW76_RS09640	COG0861	Integral membrane protein TerC family
AXW76_RS09655	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AXW76_RS09685	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AXW76_RS09700	COG0482	sulfurtransferase activity
AXW76_RS09710	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AXW76_RS09720	COG1766	The M ring may be actively involved in energy transduction
AXW76_RS09725	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AXW76_RS09735	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AXW76_RS09740	COG2204	response regulator
AXW76_RS09760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXW76_RS09765	COG1116	anion transmembrane transporter activity
AXW76_RS09770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW76_RS09775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXW76_RS09780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXW76_RS09850	COG0583	DNA-binding transcription factor activity
AXW76_RS09865	COG1280	lysine exporter protein (LysE YggA)
AXW76_RS09875	COG2010	Cytochrome c
AXW76_RS09885	COG0071	Belongs to the small heat shock protein (HSP20) family
AXW76_RS09900	COG0069	glutamate synthase activity
AXW76_RS09900	COG0070	glutamate synthase
AXW76_RS09900	COG0067	glutamate synthase
AXW76_RS09935	COG0330	HflC and HflK could
AXW76_RS09945	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AXW76_RS09955	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AXW76_RS09985	COG0251	oxidation-reduction process
AXW76_RS09995	COG4689	acetoacetate decarboxylase
AXW76_RS10015	COG0523	cobalamin synthesis protein
AXW76_RS10020	COG0803	Belongs to the bacterial solute-binding protein 9 family
AXW76_RS10025	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AXW76_RS10030	COG1121	(ABC) transporter
AXW76_RS10050	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AXW76_RS10085	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS10105	COG0318	PFAM AMP-dependent synthetase and ligase
AXW76_RS10130	COG0326	Molecular chaperone. Has ATPase activity
AXW76_RS10160	COG3547	Transposase (IS116 IS110 IS902 family)
AXW76_RS10170	COG0784	Response regulator, receiver
AXW76_RS10185	COG0778	Nitroreductase
AXW76_RS10190	COG1960	acyl-CoA dehydrogenase activity
AXW76_RS10195	COG1960	acyl-CoA dehydrogenase activity
AXW76_RS10200	COG1960	acyl-CoA dehydrogenase activity
AXW76_RS10205	COG0318	PFAM AMP-dependent synthetase and ligase
AXW76_RS10250	COG2267	carboxylic ester hydrolase activity
AXW76_RS10290	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AXW76_RS10300	COG1960	acyl-CoA dehydrogenase activity
AXW76_RS10305	COG0183	Belongs to the thiolase family
AXW76_RS10310	COG0318	PFAM AMP-dependent synthetase and ligase
AXW76_RS10335	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXW76_RS10390	COG0583	DNA-binding transcription factor activity
AXW76_RS10415	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXW76_RS10430	COG1024	Enoyl-CoA hydratase
AXW76_RS10435	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AXW76_RS10435	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS10435	COG0318	PFAM AMP-dependent synthetase and ligase
AXW76_RS10435	COG3321	synthase
AXW76_RS10435	COG0300	oxidoreductase activity
AXW76_RS10495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AXW76_RS10500	COG1024	Enoyl-CoA hydratase
AXW76_RS10515	COG2378	regulation of single-species biofilm formation
AXW76_RS10530	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXW76_RS10535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXW76_RS10540	COG0318	PFAM AMP-dependent synthetase and ligase
AXW76_RS10555	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXW76_RS10560	COG1879	ABC-type sugar transport system periplasmic component
AXW76_RS10580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXW76_RS10585	COG0842	Transport permease protein
AXW76_RS10585	COG1129	ABC transporter
AXW76_RS10590	COG0842	Transport permease protein
AXW76_RS10625	COG0656	L-ascorbic acid biosynthetic process
AXW76_RS10635	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS10640	COG0640	Transcriptional regulator
AXW76_RS10670	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS10680	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS10695	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXW76_RS10710	COG2267	carboxylic ester hydrolase activity
AXW76_RS10730	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AXW76_RS10735	COG1960	acyl-CoA dehydrogenase activity
AXW76_RS10740	COG4221	oxidoreductase activity
AXW76_RS10745	COG1024	Enoyl-CoA hydratase
AXW76_RS10760	COG0583	DNA-binding transcription factor activity
AXW76_RS10800	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AXW76_RS10805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXW76_RS10810	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
AXW76_RS10825	COG0154	amidase activity
AXW76_RS10835	COG4608	Belongs to the ABC transporter superfamily
AXW76_RS10845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW76_RS10855	COG0747	negative chemotaxis
AXW76_RS10860	COG0747	negative chemotaxis
AXW76_RS10895	COG1022	Amp-dependent synthetase and ligase
AXW76_RS10960	COG2309	aminopeptidase activity
AXW76_RS10965	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AXW76_RS10990	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AXW76_RS11005	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AXW76_RS11030	COG1024	Enoyl-CoA hydratase
AXW76_RS11040	COG1309	transcriptional regulator
AXW76_RS11060	COG0071	Belongs to the small heat shock protein (HSP20) family
AXW76_RS11065	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AXW76_RS11070	COG2610	gluconate transmembrane transporter activity
AXW76_RS11080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXW76_RS11095	COG4774	siderophore transport
AXW76_RS11100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXW76_RS11105	COG0277	FAD linked oxidase domain protein
AXW76_RS11110	COG1802	Transcriptional regulator
AXW76_RS11115	COG1032	radical SAM domain protein
AXW76_RS11120	COG1959	2 iron, 2 sulfur cluster binding
AXW76_RS11140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXW76_RS11155	COG2264	protein methyltransferase activity
AXW76_RS11190	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
AXW76_RS11220	COG2902	Dehydrogenase
AXW76_RS11245	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AXW76_RS11285	COG4584	PFAM Integrase catalytic
AXW76_RS11325	COG3328	transposase activity
AXW76_RS11330	COG4584	PFAM Integrase catalytic
AXW76_RS11335	COG4372	Transposase
AXW76_RS11380	COG2801	Transposase and inactivated derivatives
AXW76_RS11405	COG1657	PFAM Prenyltransferase squalene oxidase
AXW76_RS11415	COG0142	geranyltranstransferase activity
AXW76_RS11420	COG2124	cytochrome p450
AXW76_RS11425	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS11435	COG2124	cytochrome p450
AXW76_RS11440	COG2124	cytochrome p450
AXW76_RS11490	COG3344	reverse transcriptase
AXW76_RS11500	COG3344	reverse transcriptase
AXW76_RS11525	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AXW76_RS11545	COG1943	Transposase
AXW76_RS11550	COG0583	DNA-binding transcription factor activity
AXW76_RS11565	COG0655	NAD(P)H dehydrogenase (quinone) activity
AXW76_RS11570	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AXW76_RS11590	COG1215	transferase activity, transferring glycosyl groups
AXW76_RS11615	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AXW76_RS11630	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AXW76_RS11640	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXW76_RS11675	COG0583	DNA-binding transcription factor activity
AXW76_RS11690	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AXW76_RS11700	COG1126	abc transporter atp-binding protein
AXW76_RS11705	COG0765	amino acid transport
AXW76_RS11710	COG0765	amino acid transport
AXW76_RS11745	COG1902	pentaerythritol trinitrate reductase activity
AXW76_RS11750	COG1012	belongs to the aldehyde dehydrogenase family
AXW76_RS11765	COG2146	nitrite reductase [NAD(P)H] activity
AXW76_RS11800	COG4166	transmembrane transport
AXW76_RS11805	COG1472	Belongs to the glycosyl hydrolase 3 family
AXW76_RS11815	COG0745	RESPONSE REGULATOR receiver
AXW76_RS11820	COG2205	protein histidine kinase activity
AXW76_RS11860	COG0826	peptidase U32
AXW76_RS11905	COG1082	Xylose isomerase domain protein TIM barrel
AXW76_RS11910	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AXW76_RS11940	COG4297	protein containing double-stranded beta helix domain
AXW76_RS11945	COG0671	phosphoesterase, PA-phosphatase related
AXW76_RS12000	COG0438	transferase activity, transferring glycosyl groups
AXW76_RS12025	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AXW76_RS12030	COG3685	Protein conserved in bacteria
AXW76_RS12035	COG0723	plastoquinol--plastocyanin reductase activity
AXW76_RS12035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXW76_RS12065	COG0693	protein deglycase activity
AXW76_RS12075	COG0546	phosphoglycolate phosphatase activity
AXW76_RS12170	COG3344	reverse transcriptase
AXW76_RS12200	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXW76_RS12205	COG4372	Transposase
AXW76_RS12220	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AXW76_RS12235	COG2801	Transposase and inactivated derivatives
AXW76_RS12260	COG4584	PFAM Integrase catalytic
AXW76_RS12265	COG1484	DNA-dependent DNA replication
AXW76_RS12275	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXW76_RS12280	COG4974	Belongs to the 'phage' integrase family
AXW76_RS12290	COG4584	PFAM Integrase catalytic
AXW76_RS12295	COG4372	Transposase
AXW76_RS12300	COG2801	Transposase and inactivated derivatives
AXW76_RS12310	COG3547	Transposase (IS116 IS110 IS902 family)
AXW76_RS12330	COG3436	PFAM IS66 Orf2 family protein
AXW76_RS12335	COG2963	transposase activity
AXW76_RS12340	COG0459	protein refolding
AXW76_RS12345	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AXW76_RS12350	COG0275	rRNA processing
AXW76_RS12375	COG4372	Transposase
AXW76_RS12380	COG4372	Transposase
AXW76_RS12385	COG4584	PFAM Integrase catalytic
AXW76_RS12395	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXW76_RS12425	COG1278	Cold shock
AXW76_RS12430	COG1505	serine-type exopeptidase activity
AXW76_RS12440	COG3293	Transposase
AXW76_RS12445	COG3344	reverse transcriptase
AXW76_RS12450	COG3547	Transposase (IS116 IS110 IS902 family)
AXW76_RS12555	COG4372	Transposase
AXW76_RS12570	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AXW76_RS12585	COG4750	Nucleotidyl transferase
AXW76_RS12610	COG4886	Leucine-rich repeat (LRR) protein
AXW76_RS12615	COG4886	Leucine-rich repeat (LRR) protein
AXW76_RS12630	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AXW76_RS12630	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AXW76_RS12655	COG2801	Transposase and inactivated derivatives
AXW76_RS12695	COG0745	RESPONSE REGULATOR receiver
AXW76_RS12700	COG4964	Belongs to the GSP D family
AXW76_RS12740	COG2801	Transposase and inactivated derivatives
AXW76_RS12795	COG4792	protein secretion
AXW76_RS12800	COG4791	protein targeting
AXW76_RS12805	COG4794	Type iii secretion
AXW76_RS12810	COG4790	Type iii secretion
AXW76_RS12815	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AXW76_RS12825	COG1157	protein secretion by the type III secretion system
AXW76_RS12830	COG1317	bacterial-type flagellum organization
AXW76_RS12840	COG4669	(LipO)protein
AXW76_RS12860	COG4584	PFAM Integrase catalytic
AXW76_RS12900	COG4789	Type iii secretion
AXW76_RS12910	COG2801	Transposase and inactivated derivatives
AXW76_RS12920	COG0612	Peptidase, M16
AXW76_RS12960	COG4886	Leucine-rich repeat (LRR) protein
AXW76_RS12985	COG0535	radical SAM domain protein
AXW76_RS12990	COG5554	nitrogen fixation
AXW76_RS13010	COG3047	cAMP biosynthetic process
AXW76_RS13015	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AXW76_RS13030	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AXW76_RS13035	COG0644	oxidoreductase
AXW76_RS13040	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AXW76_RS13045	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AXW76_RS13075	COG1408	metallophosphoesterase
AXW76_RS13085	COG2255	four-way junction helicase activity
AXW76_RS13090	COG0632	four-way junction helicase activity
AXW76_RS13095	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AXW76_RS13100	COG0217	transcriptional regulatory protein
AXW76_RS13135	COG1692	metallophosphoesterase
AXW76_RS13170	COG0126	phosphoglycerate kinase activity
AXW76_RS13180	COG3588	fructose-bisphosphate aldolase
AXW76_RS13195	COG0483	inositol monophosphate 1-phosphatase activity
AXW76_RS13200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXW76_RS13205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXW76_RS13215	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AXW76_RS13235	COG1132	(ABC) transporter
AXW76_RS13240	COG0254	rRNA binding
AXW76_RS13255	COG3321	synthase
AXW76_RS13255	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS13255	COG0604	alcohol dehydrogenase
AXW76_RS13270	COG2203	Gaf domain
AXW76_RS13270	COG3706	GGDEF domain
AXW76_RS13270	COG4251	negative regulation of phosphorylation
AXW76_RS13270	COG5001	Diguanylate cyclase
AXW76_RS13280	COG2951	lytic endotransglycosylase activity
AXW76_RS13290	COG3237	CsbD-like
AXW76_RS13295	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS13300	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS13310	COG1678	Uncharacterized ACR, COG1678
AXW76_RS13325	COG0730	response to heat
AXW76_RS13330	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS13350	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AXW76_RS13355	COG4208	sulfate ABC transporter
AXW76_RS13360	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AXW76_RS13365	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AXW76_RS13370	COG0175	sulfate reduction
AXW76_RS13380	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AXW76_RS13390	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AXW76_RS13390	COG1648	precorrin-2 dehydrogenase activity
AXW76_RS13405	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AXW76_RS13410	COG3237	CsbD-like
AXW76_RS13430	COG1376	ErfK ybiS ycfS ynhG family protein
AXW76_RS13430	COG1388	LysM domain
AXW76_RS13435	COG0628	permease
AXW76_RS13470	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AXW76_RS13475	COG0830	nickel cation binding
AXW76_RS13490	COG0804	urea catabolic process
AXW76_RS13495	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AXW76_RS13500	COG0832	Belongs to the urease beta subunit family
AXW76_RS13505	COG0831	urea catabolic process
AXW76_RS13510	COG0829	nickel cation binding
AXW76_RS13540	COG0513	Belongs to the DEAD box helicase family
AXW76_RS13545	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AXW76_RS13550	COG1278	Cold shock
AXW76_RS13580	COG4964	Belongs to the GSP D family
AXW76_RS13620	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AXW76_RS13625	COG0791	NLP P60 protein
AXW76_RS13650	COG4172	Belongs to the ABC transporter superfamily
AXW76_RS13655	COG4239	(ABC) transporter, permease
AXW76_RS13660	COG4174	ABC transporter (Permease)
AXW76_RS13665	COG4166	transmembrane transport
AXW76_RS13670	COG4166	transmembrane transport
AXW76_RS13675	COG3474	cytochrome
AXW76_RS13680	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AXW76_RS13685	COG1605	Chorismate mutase
AXW76_RS13685	COG0077	Prephenate dehydratase
AXW76_RS13690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXW76_RS13720	COG0640	Transcriptional regulator
AXW76_RS13725	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AXW76_RS13740	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AXW76_RS13775	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXW76_RS13820	COG2801	Transposase and inactivated derivatives
AXW76_RS13845	COG3328	transposase activity
AXW76_RS13855	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXW76_RS13860	COG4372	Transposase
AXW76_RS13865	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXW76_RS13910	COG2433	Pfam Transposase IS66
AXW76_RS13925	COG3344	reverse transcriptase
AXW76_RS13960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXW76_RS14000	COG1181	Belongs to the D-alanine--D-alanine ligase family
AXW76_RS14010	COG0405	Gamma-glutamyltransferase
AXW76_RS14015	COG1509	lysine 2,3-aminomutase activity
AXW76_RS14030	COG4372	Transposase
AXW76_RS14045	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXW76_RS14065	COG3831	ATPase activity
AXW76_RS14125	COG2801	Transposase and inactivated derivatives
AXW76_RS14205	COG3547	Transposase (IS116 IS110 IS902 family)
AXW76_RS14210	COG4584	PFAM Integrase catalytic
AXW76_RS14305	COG4886	Leucine-rich repeat (LRR) protein
AXW76_RS14335	COG2801	Transposase and inactivated derivatives
AXW76_RS14390	COG2814	Major facilitator Superfamily
AXW76_RS14400	COG5554	nitrogen fixation
AXW76_RS14405	COG1104	cysteine desulfurase activity
AXW76_RS14410	COG0316	Belongs to the HesB IscA family
AXW76_RS14430	COG4584	PFAM Integrase catalytic
AXW76_RS14450	COG5420	small protein containing a coiled-coil domain
AXW76_RS14465	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AXW76_RS14470	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AXW76_RS14475	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AXW76_RS14480	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AXW76_RS14505	COG0396	ATPase activity
AXW76_RS14515	COG0686	Belongs to the AlaDH PNT family
AXW76_RS14550	COG0582	viral genome integration into host DNA
AXW76_RS14625	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXW76_RS14655	COG4372	Transposase
AXW76_RS14675	COG4372	Transposase
AXW76_RS14685	COG0582	viral genome integration into host DNA
AXW76_RS14705	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AXW76_RS14725	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AXW76_RS14735	COG1301	dicarboxylic acid transport
AXW76_RS14750	COG4191	Histidine kinase
AXW76_RS14755	COG4566	intracellular signal transduction
AXW76_RS14760	COG4566	intracellular signal transduction
AXW76_RS14790	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXW76_RS14815	COG3547	Transposase (IS116 IS110 IS902 family)
AXW76_RS14885	COG3047	cAMP biosynthetic process
AXW76_RS14900	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AXW76_RS14905	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AXW76_RS14910	COG0328	RNA-DNA hybrid ribonuclease activity
AXW76_RS14915	COG0678	peroxiredoxin activity
AXW76_RS14915	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AXW76_RS14925	COG0318	PFAM AMP-dependent synthetase and ligase
AXW76_RS14930	COG1686	Belongs to the peptidase S11 family
AXW76_RS14935	COG1132	(ABC) transporter
AXW76_RS14950	COG0140	phosphoribosyl-ATP diphosphatase activity
AXW76_RS14955	COG1238	metal cluster binding
AXW76_RS14965	COG1027	Aspartate ammonia-lyase
AXW76_RS14990	COG2070	2-Nitropropane dioxygenase
AXW76_RS15015	COG4585	Histidine kinase
AXW76_RS15095	COG0667	Aldo Keto reductase
AXW76_RS15120	COG4191	Histidine kinase
AXW76_RS15125	COG4716	Myosin-crossreactive antigen
AXW76_RS15130	COG1022	Amp-dependent synthetase and ligase
AXW76_RS15140	COG1335	isochorismatase
AXW76_RS15170	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AXW76_RS15175	COG2186	Transcriptional regulator
AXW76_RS15195	COG3052	prosthetic group binding
AXW76_RS15215	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AXW76_RS15230	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AXW76_RS15235	COG0424	maF-like protein
AXW76_RS15240	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AXW76_RS15245	COG5328	Belongs to the UPF0262 family
AXW76_RS15250	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AXW76_RS15260	COG0702	epimerase
AXW76_RS15305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AXW76_RS15320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXW76_RS15325	COG2197	response regulator
AXW76_RS15340	COG3971	2-oxopent-4-enoate hydratase activity
AXW76_RS15345	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXW76_RS15355	COG3181	Tripartite tricarboxylate transporter family receptor
AXW76_RS15375	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXW76_RS15395	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AXW76_RS15400	COG3454	Phosphonate metabolism
AXW76_RS15405	COG4778	phosphonate C-P lyase system protein PhnL
AXW76_RS15410	COG4107	phosphonate C-P lyase system protein PhnK
AXW76_RS15415	COG3627	carbon phosphorus lyase activity
AXW76_RS15425	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AXW76_RS15430	COG3624	Phosphonate C-P lyase system protein PhnG
AXW76_RS15435	COG2188	Transcriptional regulator
AXW76_RS15440	COG2020	methyltransferase activity
AXW76_RS15485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW76_RS15530	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AXW76_RS15535	COG0156	8-amino-7-oxononanoate synthase activity
AXW76_RS15540	COG2205	protein histidine kinase activity
AXW76_RS15540	COG0784	Response regulator, receiver
AXW76_RS15550	COG0596	Alpha beta hydrolase
AXW76_RS15555	COG1764	response to oxidative stress
AXW76_RS15580	COG0432	Pfam Uncharacterised protein family UPF0047
AXW76_RS15595	COG0356	it plays a direct role in the translocation of protons across the membrane
AXW76_RS15605	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AXW76_RS15610	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AXW76_RS15620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXW76_RS15625	COG0612	Peptidase, M16
AXW76_RS15650	COG3346	SURF1 family
AXW76_RS15665	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AXW76_RS15675	COG0109	protoheme IX farnesyltransferase activity
AXW76_RS15680	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AXW76_RS15685	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AXW76_RS15695	COG0312	modulator of DNA gyrase
AXW76_RS15700	COG0681	Belongs to the peptidase S26 family
AXW76_RS15725	COG0625	glutathione transferase activity
AXW76_RS15740	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXW76_RS15740	COG1024	Enoyl-CoA hydratase
AXW76_RS15745	COG0183	Belongs to the thiolase family
AXW76_RS15750	COG1960	acyl-CoA dehydrogenase activity
AXW76_RS15760	COG1695	Transcriptional regulator
AXW76_RS15770	COG0730	response to heat
AXW76_RS15790	COG0583	DNA-binding transcription factor activity
AXW76_RS15800	COG1201	RNA secondary structure unwinding
AXW76_RS15830	COG1234	tRNA 3'-trailer cleavage
AXW76_RS15840	COG0167	dihydroorotate dehydrogenase activity
AXW76_RS15875	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
AXW76_RS15885	COG1999	signal sequence binding
AXW76_RS15910	COG0251	oxidation-reduction process
AXW76_RS15940	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXW76_RS15945	COG1129	ABC transporter
AXW76_RS15950	COG2115	Belongs to the xylose isomerase family
AXW76_RS15955	COG1070	Carbohydrate kinase
AXW76_RS15975	COG1396	sequence-specific DNA binding
AXW76_RS15985	COG2267	carboxylic ester hydrolase activity
AXW76_RS16010	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AXW76_RS16050	COG0717	Belongs to the dCTP deaminase family
AXW76_RS16075	COG2967	ApaG domain
AXW76_RS16085	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AXW76_RS16090	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AXW76_RS16100	COG0745	RESPONSE REGULATOR receiver
AXW76_RS16105	COG0704	Plays a role in the regulation of phosphate uptake
AXW76_RS16110	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AXW76_RS16115	COG0581	inorganic phosphate transmembrane transporter activity
AXW76_RS16120	COG0573	inorganic phosphate transmembrane transporter activity
AXW76_RS16130	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AXW76_RS16135	COG5002	protein histidine kinase activity
AXW76_RS16155	COG0596	Alpha beta hydrolase
AXW76_RS16170	COG2885	chlorophyll binding
AXW76_RS16170	COG3047	cAMP biosynthetic process
AXW76_RS16180	COG4584	PFAM Integrase catalytic
AXW76_RS16215	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AXW76_RS16220	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AXW76_RS16265	COG1414	Transcriptional regulator
AXW76_RS16270	COG4638	Rieske (2fe-2S)
AXW76_RS16310	COG3916	Acyl-homoserine-lactone synthase
AXW76_RS16315	COG2197	response regulator
AXW76_RS16320	COG0583	DNA-binding transcription factor activity
AXW76_RS16325	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AXW76_RS16340	COG4177	L-phenylalanine transmembrane transporter activity
AXW76_RS16365	COG1252	NADH dehydrogenase
AXW76_RS16380	COG2124	cytochrome p450
AXW76_RS16390	COG0318	PFAM AMP-dependent synthetase and ligase
AXW76_RS16405	COG1802	Transcriptional regulator
AXW76_RS16425	COG4172	Belongs to the ABC transporter superfamily
AXW76_RS16430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW76_RS16435	COG0601	transmembrane transport
AXW76_RS16440	COG0747	negative chemotaxis
AXW76_RS16460	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXW76_RS16470	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXW76_RS16475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW76_RS16475	COG4191	Histidine kinase
AXW76_RS16480	COG3437	response regulator, receiver
AXW76_RS16480	COG0784	Response regulator, receiver
AXW76_RS16490	COG1595	DNA-templated transcription, initiation
AXW76_RS16515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW76_RS16520	COG1960	acyl-CoA dehydrogenase activity
AXW76_RS16525	COG1960	acyl-CoA dehydrogenase activity
AXW76_RS16535	COG2514	catechol 2,3-dioxygenase activity
AXW76_RS16545	COG2814	Major facilitator Superfamily
AXW76_RS16550	COG1505	serine-type exopeptidase activity
AXW76_RS16560	COG4654	Cytochrome c, class I
AXW76_RS16585	COG0737	Belongs to the 5'-nucleotidase family
AXW76_RS16605	COG2271	Major facilitator Superfamily
AXW76_RS16635	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AXW76_RS16640	COG0683	leucine binding
AXW76_RS16670	COG0601	transmembrane transport
AXW76_RS16675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW76_RS16680	COG0444	Belongs to the ABC transporter superfamily
AXW76_RS16685	COG4608	Belongs to the ABC transporter superfamily
AXW76_RS16705	COG0439	Biotin carboxylase
AXW76_RS16710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AXW76_RS16715	COG1960	acyl-CoA dehydrogenase activity
AXW76_RS16765	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AXW76_RS16805	COG2198	Histidine kinase
AXW76_RS16805	COG0784	Response regulator, receiver
AXW76_RS16805	COG5002	protein histidine kinase activity
AXW76_RS16810	COG0745	RESPONSE REGULATOR receiver
AXW76_RS16815	COG2072	flavoprotein involved in K transport
AXW76_RS16830	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AXW76_RS16835	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AXW76_RS16840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AXW76_RS16850	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AXW76_RS16885	COG3300	MHYT domain
AXW76_RS16885	COG5001	Diguanylate cyclase
AXW76_RS16900	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AXW76_RS16905	COG0142	geranyltranstransferase activity
AXW76_RS16945	COG0025	NhaP-type Na H and K H
AXW76_RS16960	COG2175	clavaminate synthase activity
AXW76_RS16965	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AXW76_RS16985	COG1566	PFAM secretion protein HlyD family protein
AXW76_RS16990	COG2814	Major facilitator Superfamily
AXW76_RS17005	COG3485	protocatechuate 3,4-dioxygenase
AXW76_RS17010	COG3485	protocatechuate 3,4-dioxygenase
AXW76_RS17015	COG3485	protocatechuate 3,4-dioxygenase
AXW76_RS17020	COG0183	Belongs to the thiolase family
AXW76_RS17025	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AXW76_RS17050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW76_RS17090	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AXW76_RS17115	COG1131	(ABC) transporter
AXW76_RS17125	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AXW76_RS17140	COG0366	Alpha amylase catalytic
AXW76_RS17145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXW76_RS17155	COG0477	Major facilitator Superfamily
AXW76_RS17175	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS17185	COG5001	Diguanylate cyclase
AXW76_RS17210	COG0411	ABC transporter
AXW76_RS17230	COG5001	Diguanylate cyclase
AXW76_RS17260	COG4372	Transposase
AXW76_RS17330	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AXW76_RS17345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXW76_RS17385	COG0318	PFAM AMP-dependent synthetase and ligase
AXW76_RS17410	COG0412	Dienelactone hydrolase
AXW76_RS17425	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXW76_RS17435	COG0268	Binds directly to 16S ribosomal RNA
AXW76_RS17440	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AXW76_RS17450	COG2852	Protein conserved in bacteria
AXW76_RS17455	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AXW76_RS17485	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AXW76_RS17490	COG0534	Mate efflux family protein
AXW76_RS17530	COG1741	Belongs to the pirin family
AXW76_RS17560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXW76_RS17570	COG0180	Tryptophanyl-tRNA synthetase
AXW76_RS17600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AXW76_RS17610	COG1702	phosphate starvation-inducible protein PhoH
AXW76_RS17615	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AXW76_RS17620	COG1253	flavin adenine dinucleotide binding
AXW76_RS17625	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AXW76_RS17630	COG1396	sequence-specific DNA binding
AXW76_RS17640	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AXW76_RS17650	COG0779	Required for maturation of 30S ribosomal subunits
AXW76_RS17670	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AXW76_RS17675	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AXW76_RS17680	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AXW76_RS17685	COG1185	polyribonucleotide nucleotidyltransferase activity
AXW76_RS17690	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AXW76_RS17725	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AXW76_RS17735	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AXW76_RS17755	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AXW76_RS17770	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AXW76_RS17775	COG2226	methyltransferase
AXW76_RS17780	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AXW76_RS17785	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AXW76_RS17790	COG0756	dUTP diphosphatase activity
AXW76_RS17795	COG2205	protein histidine kinase activity
AXW76_RS17800	COG3178	'Phosphotransferase
AXW76_RS17810	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AXW76_RS17820	COG1074	ATP-dependent DNA helicase activity
AXW76_RS17835	COG0285	dihydrofolate synthase activity
AXW76_RS17840	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AXW76_RS17845	COG0159	tryptophan synthase activity
AXW76_RS17850	COG0133	tryptophan synthase activity
AXW76_RS17855	COG0135	phosphoribosylanthranilate isomerase activity
AXW76_RS17865	COG0776	regulation of translation
AXW76_RS17870	COG0616	signal peptide processing
AXW76_RS17875	COG0539	negative regulation of cytoplasmic translation
AXW76_RS17880	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AXW76_RS17885	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AXW76_RS17900	COG1846	Transcriptional regulator
AXW76_RS17905	COG1764	response to oxidative stress
AXW76_RS17925	COG0395	ABC-type sugar transport system, permease component
AXW76_RS17930	COG3842	ATPase activity
AXW76_RS17935	COG0071	Belongs to the small heat shock protein (HSP20) family
AXW76_RS17955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXW76_RS17960	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AXW76_RS17965	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AXW76_RS17970	COG1137	ATPase activity
AXW76_RS17975	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AXW76_RS17990	COG2814	Major facilitator Superfamily
AXW76_RS18005	COG1968	undecaprenyl-diphosphatase activity
AXW76_RS18015	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AXW76_RS18035	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AXW76_RS18045	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AXW76_RS18050	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AXW76_RS18060	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AXW76_RS18085	COG1937	Protein conserved in bacteria
AXW76_RS18100	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AXW76_RS18105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXW76_RS18115	COG2814	Major facilitator Superfamily
AXW76_RS18155	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AXW76_RS18160	COG0588	phosphoglycerate mutase activity
AXW76_RS18165	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AXW76_RS18175	COG0284	orotidine-5'-phosphate decarboxylase activity
AXW76_RS18180	COG0431	NADPH-dependent FMN reductase
AXW76_RS18185	COG3963	phosphatidate phosphatase activity
AXW76_RS18190	COG0484	heat shock protein binding
AXW76_RS18195	COG0443	Heat shock 70 kDa protein
AXW76_RS18205	COG1335	isochorismatase
AXW76_RS18210	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AXW76_RS18215	COG1420	regulation of RNA biosynthetic process
AXW76_RS18220	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AXW76_RS18225	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AXW76_RS18230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AXW76_RS18240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AXW76_RS18245	COG0792	nuclease activity
AXW76_RS18250	COG0189	ligase activity
AXW76_RS18260	COG0606	chelatase, subunit chli
AXW76_RS18270	COG2205	protein histidine kinase activity
AXW76_RS18270	COG0784	Response regulator, receiver
AXW76_RS18270	COG5002	protein histidine kinase activity
AXW76_RS18280	COG0628	permease
AXW76_RS18285	COG1072	(Pantothenic acid kinase))
AXW76_RS18290	COG0140	phosphoribosyl-ATP diphosphatase activity
AXW76_RS18295	COG0107	imidazoleglycerol-phosphate synthase activity
AXW76_RS18300	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AXW76_RS18305	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AXW76_RS18315	COG0131	Imidazoleglycerol-phosphate dehydratase
AXW76_RS18320	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AXW76_RS18335	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AXW76_RS18350	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AXW76_RS18360	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AXW76_RS18365	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AXW76_RS18370	COG0237	dephospho-CoA kinase activity
AXW76_RS18375	COG0424	maF-like protein
AXW76_RS18380	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AXW76_RS18385	COG1981	membrane
AXW76_RS18390	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AXW76_RS18400	COG0445	tRNA wobble uridine modification
AXW76_RS18405	COG0357	Ribosomal RNA small subunit methyltransferase G
AXW76_RS18430	COG0495	leucyl-tRNA aminoacylation
AXW76_RS18445	COG5001	Diguanylate cyclase
AXW76_RS18445	COG4251	negative regulation of phosphorylation
AXW76_RS18445	COG3706	GGDEF domain
AXW76_RS18445	COG2203	Gaf domain
AXW76_RS18465	COG0745	RESPONSE REGULATOR receiver
AXW76_RS18480	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AXW76_RS18485	COG1674	ftsk spoiiie
AXW76_RS18490	COG0436	Aminotransferase
AXW76_RS18500	COG0004	ammonium transporteR
AXW76_RS18505	COG0347	Belongs to the P(II) protein family
AXW76_RS18515	COG4584	PFAM Integrase catalytic
AXW76_RS18520	COG0740	serine-type endopeptidase activity
AXW76_RS18530	COG0640	Transcriptional regulator
AXW76_RS18535	COG0004	ammonium transporteR
AXW76_RS18540	COG0347	Belongs to the P(II) protein family
AXW76_RS18550	COG1946	Acyl-CoA thioesterase
AXW76_RS18555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXW76_RS18560	COG2835	tetraacyldisaccharide 4'-kinase activity
AXW76_RS18600	COG3118	belongs to the thioredoxin family
AXW76_RS18610	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AXW76_RS18635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXW76_RS18650	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AXW76_RS18660	COG0534	Mate efflux family protein
AXW76_RS18675	COG2814	Major facilitator Superfamily
AXW76_RS18680	COG0405	Gamma-glutamyltransferase
AXW76_RS18690	COG0138	bifunctional purine biosynthesis protein purh
AXW76_RS18710	COG4529	Protein conserved in bacteria
AXW76_RS18730	COG1376	ErfK ybiS ycfS ynhG family protein
AXW76_RS18735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AXW76_RS18750	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AXW76_RS18760	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AXW76_RS18765	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AXW76_RS18805	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AXW76_RS18850	COG3547	Transposase (IS116 IS110 IS902 family)
AXW76_RS18890	COG4584	PFAM Integrase catalytic
AXW76_RS18930	COG2814	Major facilitator Superfamily
AXW76_RS18955	COG4221	oxidoreductase activity
AXW76_RS18965	COG1024	Enoyl-CoA hydratase
AXW76_RS18985	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AXW76_RS18990	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AXW76_RS18995	COG1247	-acetyltransferase
AXW76_RS19015	COG3011	Protein conserved in bacteria
AXW76_RS19025	COG1217	gtp-binding protein TYPA
AXW76_RS19055	COG0784	Response regulator, receiver
AXW76_RS19070	COG2154	pterin-4-alpha-carbinolamine dehydratase
AXW76_RS19090	COG3321	synthase
AXW76_RS19090	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS19090	COG0604	alcohol dehydrogenase
AXW76_RS19095	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS19105	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AXW76_RS19115	COG0671	phosphoesterase, PA-phosphatase related
AXW76_RS19120	COG0137	argininosuccinate synthase activity
AXW76_RS19145	COG4178	(ABC) transporter
AXW76_RS19150	COG4191	Histidine kinase
AXW76_RS19150	COG0784	Response regulator, receiver
AXW76_RS19175	COG0583	DNA-binding transcription factor activity
AXW76_RS19180	COG0730	response to heat
AXW76_RS19185	COG0318	PFAM AMP-dependent synthetase and ligase
AXW76_RS19190	COG4221	oxidoreductase activity
AXW76_RS19195	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AXW76_RS19200	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AXW76_RS19205	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AXW76_RS19215	COG0473	3-isopropylmalate dehydrogenase activity
AXW76_RS19230	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AXW76_RS19235	COG0288	reversible hydration of carbon dioxide
AXW76_RS19240	COG2301	Belongs to the HpcH HpaI aldolase family
AXW76_RS19260	COG0066	3-isopropylmalate dehydratase activity
AXW76_RS19310	COG0335	large ribosomal subunit rRNA binding
AXW76_RS19315	COG0336	Belongs to the RNA methyltransferase TrmD family
AXW76_RS19330	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AXW76_RS19335	COG0228	four-way junction DNA binding
AXW76_RS19340	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AXW76_RS19365	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AXW76_RS19370	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AXW76_RS19380	COG0564	pseudouridine synthase activity
AXW76_RS19385	COG0552	protein localization to endoplasmic reticulum
AXW76_RS19390	COG2917	probably involved in intracellular septation
AXW76_RS19395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXW76_RS19405	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AXW76_RS19410	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AXW76_RS19415	COG4133	protoheme IX ABC transporter activity
AXW76_RS19420	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AXW76_RS19440	COG0670	Belongs to the BI1 family
AXW76_RS19445	COG1136	(ABC) transporter
AXW76_RS19445	COG0577	efflux transmembrane transporter activity
AXW76_RS19450	COG4181	ATPase activity
AXW76_RS19455	COG2755	lipolytic protein G-D-S-L family
AXW76_RS19460	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AXW76_RS19465	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AXW76_RS19470	COG0039	L-malate dehydrogenase activity
AXW76_RS19475	COG0045	succinate-CoA ligase (ADP-forming) activity
AXW76_RS19485	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AXW76_RS19495	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXW76_RS19500	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS19505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXW76_RS19520	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AXW76_RS19530	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AXW76_RS19535	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AXW76_RS19540	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AXW76_RS19545	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AXW76_RS19550	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AXW76_RS19555	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AXW76_RS19575	COG0494	nUDIX hydrolase
AXW76_RS19580	COG1051	belongs to the nudix hydrolase family
AXW76_RS19590	COG0793	Belongs to the peptidase S41A family
AXW76_RS19600	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AXW76_RS19610	COG0799	negative regulation of ribosome biogenesis
AXW76_RS19615	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AXW76_RS19620	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AXW76_RS19625	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AXW76_RS19640	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AXW76_RS19660	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AXW76_RS19665	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AXW76_RS19685	COG4372	Transposase
AXW76_RS19690	COG3344	reverse transcriptase
AXW76_RS19695	COG4372	Transposase
AXW76_RS19765	COG1783	phage Terminase large subunit
AXW76_RS19830	COG0473	3-isopropylmalate dehydrogenase activity
AXW76_RS19845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW76_RS19850	COG0583	DNA-binding transcription factor activity
AXW76_RS19860	COG3181	Tripartite tricarboxylate transporter family receptor
AXW76_RS19885	COG0697	spore germination
AXW76_RS19890	COG0697	spore germination
AXW76_RS19935	COG3437	response regulator, receiver
AXW76_RS19945	COG0835	chemotaxis
AXW76_RS19965	COG2201	protein-glutamate methylesterase activity
AXW76_RS19975	COG4566	intracellular signal transduction
AXW76_RS20020	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AXW76_RS20030	COG1696	Membrane protein involved in D-alanine export
AXW76_RS20070	COG2706	6-phosphogluconolactonase activity
AXW76_RS20085	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AXW76_RS20115	COG2171	N-acyltransferase activity
AXW76_RS20130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AXW76_RS20175	COG1846	Transcriptional regulator
AXW76_RS20180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXW76_RS20195	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AXW76_RS20205	COG3813	Protein conserved in bacteria
AXW76_RS20210	COG1522	sequence-specific DNA binding
AXW76_RS20220	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXW76_RS20265	COG5002	protein histidine kinase activity
AXW76_RS20265	COG0784	Response regulator, receiver
AXW76_RS20265	COG2198	Histidine kinase
AXW76_RS20295	COG1877	trehalose-phosphatase activity
AXW76_RS20300	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AXW76_RS20335	COG0210	DNA helicase
AXW76_RS20340	COG4372	Transposase
AXW76_RS20380	COG3052	prosthetic group binding
AXW76_RS20400	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AXW76_RS20415	COG2169	Transcriptional regulator
AXW76_RS20420	COG1566	PFAM secretion protein HlyD family protein
AXW76_RS20440	COG4566	intracellular signal transduction
AXW76_RS20445	COG4191	Histidine kinase
AXW76_RS20465	COG3257	ureidoglycine aminohydrolase activity
AXW76_RS20470	COG0583	DNA-binding transcription factor activity
AXW76_RS20475	COG2814	Major facilitator Superfamily
AXW76_RS20480	COG0667	Aldo Keto reductase
AXW76_RS20500	COG2873	o-acetylhomoserine
AXW76_RS20520	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AXW76_RS20525	COG1522	sequence-specific DNA binding
AXW76_RS20535	COG2072	flavoprotein involved in K transport
AXW76_RS20540	COG0583	DNA-binding transcription factor activity
AXW76_RS20570	COG0657	acetylesterase activity
AXW76_RS20585	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AXW76_RS20600	COG0697	spore germination
AXW76_RS20610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXW76_RS20625	COG2890	protein-(glutamine-N5) methyltransferase activity
AXW76_RS20630	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AXW76_RS20635	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
AXW76_RS20640	COG0527	aspartate kinase activity
AXW76_RS20650	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AXW76_RS20665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AXW76_RS20670	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AXW76_RS20690	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AXW76_RS20695	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AXW76_RS20700	COG0653	protein targeting
AXW76_RS20710	COG1846	Transcriptional regulator
AXW76_RS20740	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AXW76_RS20750	COG3034	peptidoglycan biosynthetic process
AXW76_RS20755	COG0825	malonyl-CoA metabolic process
AXW76_RS20760	COG4974	Belongs to the 'phage' integrase family
AXW76_RS20770	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AXW76_RS20775	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AXW76_RS20780	COG4536	flavin adenine dinucleotide binding
AXW76_RS20795	COG0372	Belongs to the citrate synthase family
AXW76_RS20800	COG0372	Belongs to the citrate synthase family
AXW76_RS20835	COG1902	pentaerythritol trinitrate reductase activity
AXW76_RS20880	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AXW76_RS20910	COG4372	Transposase
AXW76_RS20920	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AXW76_RS20935	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AXW76_RS20940	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AXW76_RS20950	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AXW76_RS20965	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AXW76_RS20970	COG1845	cytochrome c oxidase, subunit III
AXW76_RS20975	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AXW76_RS20980	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AXW76_RS20985	COG0477	Major facilitator Superfamily
AXW76_RS21005	COG1024	Enoyl-CoA hydratase
AXW76_RS21025	COG2801	Transposase and inactivated derivatives
AXW76_RS21030	COG0582	viral genome integration into host DNA
AXW76_RS21060	COG4386	tail sheath protein
AXW76_RS21085	COG0740	serine-type endopeptidase activity
AXW76_RS21155	COG1475	DNA binding
AXW76_RS21160	COG4372	Transposase
AXW76_RS21195	COG4584	PFAM Integrase catalytic
AXW76_RS21325	COG1960	acyl-CoA dehydrogenase activity
AXW76_RS21340	COG2261	transglycosylase associated protein
AXW76_RS21350	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AXW76_RS21375	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AXW76_RS21500	COG2234	aminopeptidase activity
AXW76_RS21540	COG3436	PFAM IS66 Orf2 family protein
AXW76_RS21545	COG2433	Pfam Transposase IS66
AXW76_RS21550	COG3318	Belongs to the UPF0149 family
AXW76_RS21555	COG3547	Transposase (IS116 IS110 IS902 family)
AXW76_RS21635	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXW76_RS21720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXW76_RS21740	COG1960	acyl-CoA dehydrogenase activity
AXW76_RS21755	COG1024	Enoyl-CoA hydratase
AXW76_RS21765	COG0583	DNA-binding transcription factor activity
AXW76_RS21770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXW76_RS21800	COG1846	Transcriptional regulator
AXW76_RS21825	COG2130	NADP-dependent
AXW76_RS21830	COG1301	dicarboxylic acid transport
AXW76_RS21850	COG0069	glutamate synthase activity
AXW76_RS21860	COG1253	flavin adenine dinucleotide binding
AXW76_RS21870	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AXW76_RS21895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW76_RS21900	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AXW76_RS21915	COG4941	Belongs to the sigma-70 factor family
AXW76_RS21940	COG0683	leucine binding
AXW76_RS21955	COG2003	Belongs to the UPF0758 family
AXW76_RS21970	COG0024	Methionine aminopeptidase
AXW76_RS21975	COG3264	Mechanosensitive ion channel
AXW76_RS21975	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AXW76_RS21980	COG3263	regulation of cellular component size
AXW76_RS21990	COG0586	Pfam SNARE associated Golgi protein
AXW76_RS22000	COG0438	transferase activity, transferring glycosyl groups
AXW76_RS22005	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AXW76_RS22010	COG4149	molybdate abc transporter
AXW76_RS22015	COG0725	ABC transporter, periplasmic molybdate-binding protein
AXW76_RS22025	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AXW76_RS22030	COG5001	Diguanylate cyclase
AXW76_RS22035	COG1960	acyl-CoA dehydrogenase activity
AXW76_RS22045	COG1794	racemase activity, acting on amino acids and derivatives
AXW76_RS22065	COG0481	GTPase activity
AXW76_RS22080	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AXW76_RS22080	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXW76_RS22090	COG2205	protein histidine kinase activity
AXW76_RS22095	COG0745	RESPONSE REGULATOR receiver
AXW76_RS22110	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AXW76_RS22120	COG0058	SHG alpha-glucan phosphorylase activity
AXW76_RS22145	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AXW76_RS22150	COG0625	glutathione transferase activity
AXW76_RS22155	COG1280	lysine exporter protein (LysE YggA)
AXW76_RS22160	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AXW76_RS22160	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AXW76_RS22170	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AXW76_RS22175	COG1643	Atp-dependent helicase
AXW76_RS22185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AXW76_RS22190	COG1522	sequence-specific DNA binding
AXW76_RS22195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXW76_RS22225	COG0765	amino acid transport
AXW76_RS22245	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AXW76_RS22250	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AXW76_RS22270	COG0242	peptide deformylase activity
AXW76_RS22280	COG0101	tRNA pseudouridine synthase activity
AXW76_RS22285	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AXW76_RS22290	COG3152	Membrane
AXW76_RS22295	COG2171	N-acyltransferase activity
AXW76_RS22310	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AXW76_RS22320	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AXW76_RS22335	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AXW76_RS22460	COG5489	Protein of unknown function (DUF736)
AXW76_RS22475	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXW76_RS22500	COG4178	(ABC) transporter
AXW76_RS22505	COG3920	Histidine kinase
AXW76_RS22520	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AXW76_RS22530	COG3237	CsbD-like
AXW76_RS22545	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AXW76_RS22550	COG3237	CsbD-like
AXW76_RS22565	COG0071	Belongs to the small heat shock protein (HSP20) family
AXW76_RS22580	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AXW76_RS22585	COG3038	cytochrome b561
AXW76_RS22595	COG1408	metallophosphoesterase
AXW76_RS22610	COG0662	Cupin 2, conserved barrel domain protein
AXW76_RS22700	COG3550	peptidyl-serine autophosphorylation
AXW76_RS22745	COG4584	PFAM Integrase catalytic
AXW76_RS22780	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AXW76_RS22790	COG2771	luxR family
AXW76_RS22815	COG0789	Transcriptional regulator
AXW76_RS22820	COG0583	DNA-binding transcription factor activity
AXW76_RS22825	COG0583	DNA-binding transcription factor activity
AXW76_RS22830	COG3153	acetyltransferase
AXW76_RS22840	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AXW76_RS22845	COG2192	nodulation
AXW76_RS22850	COG1131	(ABC) transporter
AXW76_RS22855	COG0842	Transport permease protein
AXW76_RS22860	COG2192	nodulation
AXW76_RS22865	COG2192	nodulation
AXW76_RS22880	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS22890	COG2086	electron transfer activity
AXW76_RS22900	COG4372	Transposase
AXW76_RS22905	COG3318	Belongs to the UPF0149 family
AXW76_RS22910	COG2433	Pfam Transposase IS66
AXW76_RS22915	COG3436	PFAM IS66 Orf2 family protein
AXW76_RS22920	COG2963	transposase activity
AXW76_RS22925	COG4974	Belongs to the 'phage' integrase family
AXW76_RS22930	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXW76_RS22960	COG1278	Cold shock
AXW76_RS23015	COG0135	phosphoribosylanthranilate isomerase activity
AXW76_RS23050	COG0784	Response regulator, receiver
AXW76_RS23050	COG2205	protein histidine kinase activity
AXW76_RS23050	COG2198	Histidine kinase
AXW76_RS23070	COG2086	electron transfer activity
AXW76_RS23080	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXW76_RS23090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXW76_RS23095	COG0165	Argininosuccinate lyase
AXW76_RS23105	COG0019	diaminopimelate decarboxylase activity
AXW76_RS23115	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AXW76_RS23130	COG2204	response regulator
AXW76_RS23145	COG2801	Transposase and inactivated derivatives
AXW76_RS23150	COG2884	Cell division ATP-binding protein ftsE
AXW76_RS23180	COG0287	Prephenate dehydrogenase
AXW76_RS23195	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXW76_RS23200	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXW76_RS23200	COG2813	Specifically methylates the guanine in position
AXW76_RS23220	COG0542	response to heat
AXW76_RS23235	COG0739	heme binding
AXW76_RS23285	COG4584	PFAM Integrase catalytic
AXW76_RS23295	COG4372	Transposase
AXW76_RS23315	COG0582	viral genome integration into host DNA
AXW76_RS23325	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AXW76_RS23370	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AXW76_RS23370	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AXW76_RS23385	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXW76_RS23400	COG0601	transmembrane transport
AXW76_RS23405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW76_RS23415	COG4608	Belongs to the ABC transporter superfamily
AXW76_RS23445	COG4251	negative regulation of phosphorylation
AXW76_RS23445	COG3706	GGDEF domain
AXW76_RS23445	COG2203	Gaf domain
AXW76_RS23445	COG5001	Diguanylate cyclase
AXW76_RS23450	COG3360	Dodecin
AXW76_RS23455	COG2273	Hydrolase Family 16
AXW76_RS23455	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AXW76_RS23460	COG2723	6-phospho-beta-galactosidase activity
AXW76_RS23570	COG0025	NhaP-type Na H and K H
AXW76_RS23585	COG0435	Glutathione S-transferase
AXW76_RS23605	COG1335	isochorismatase
AXW76_RS23675	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AXW76_RS23695	COG2205	protein histidine kinase activity
AXW76_RS23695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW76_RS23705	COG0438	transferase activity, transferring glycosyl groups
AXW76_RS23730	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AXW76_RS23750	COG2801	Transposase and inactivated derivatives
AXW76_RS23785	COG3547	Transposase (IS116 IS110 IS902 family)
AXW76_RS23805	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AXW76_RS23850	COG0824	Thioesterase
AXW76_RS23855	COG0824	Thioesterase
AXW76_RS23865	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AXW76_RS23865	COG0519	Catalyzes the synthesis of GMP from XMP
AXW76_RS23885	COG0765	amino acid transport
AXW76_RS23895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW76_RS23915	COG0402	S-adenosylhomocysteine deaminase activity
AXW76_RS23930	COG3842	ATPase activity
AXW76_RS23935	COG1176	ABC-type spermidine putrescine transport system, permease component I
AXW76_RS23940	COG1177	transmembrane transport
AXW76_RS23970	COG0488	(ABC) transporter
AXW76_RS23975	COG1301	dicarboxylic acid transport
AXW76_RS23980	COG2233	PERMEase
AXW76_RS24035	COG0625	glutathione transferase activity
AXW76_RS24050	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXW76_RS24055	COG3795	YCII-related domain
AXW76_RS24060	COG4941	Belongs to the sigma-70 factor family
AXW76_RS24090	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS24130	COG1045	serine acetyltransferase
AXW76_RS24160	COG0823	Involved in the tonB-independent uptake of proteins
AXW76_RS24165	COG5001	Diguanylate cyclase
AXW76_RS24175	COG2885	chlorophyll binding
AXW76_RS24185	COG0037	tRNA processing
AXW76_RS24190	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AXW76_RS24225	COG1309	transcriptional regulator
AXW76_RS24235	COG0469	pyruvate kinase activity
AXW76_RS24250	COG3750	Belongs to the UPF0335 family
AXW76_RS24265	COG2989	Protein conserved in bacteria
AXW76_RS24270	COG2204	response regulator
AXW76_RS24315	COG0387	Pfam Sodium calcium exchanger
AXW76_RS24335	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AXW76_RS24340	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AXW76_RS24345	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AXW76_RS24350	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AXW76_RS24355	COG3447	MASE1 domain protein
AXW76_RS24355	COG5002	protein histidine kinase activity
AXW76_RS24355	COG5001	Diguanylate cyclase
AXW76_RS24410	COG3842	ATPase activity
AXW76_RS24415	COG1176	ABC-type spermidine putrescine transport system, permease component I
AXW76_RS24420	COG1177	transmembrane transport
AXW76_RS24435	COG1175	transmembrane transport
AXW76_RS24445	COG0583	DNA-binding transcription factor activity
AXW76_RS24450	COG2828	Protein conserved in bacteria
AXW76_RS24455	COG1301	dicarboxylic acid transport
AXW76_RS24505	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AXW76_RS24530	COG4566	intracellular signal transduction
AXW76_RS24540	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AXW76_RS24545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXW76_RS24560	COG4771	TonB-dependent receptor
AXW76_RS24580	COG0848	biopolymer transport protein
AXW76_RS24605	COG0596	Alpha beta hydrolase
AXW76_RS24610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXW76_RS24615	COG0395	ABC-type sugar transport system, permease component
AXW76_RS24620	COG1175	transmembrane transport
AXW76_RS24630	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AXW76_RS24690	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AXW76_RS24695	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AXW76_RS24740	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXW76_RS24745	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXW76_RS24755	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AXW76_RS24760	COG3005	denitrification pathway
AXW76_RS24765	COG3043	anaerobic respiration
AXW76_RS24770	COG0243	molybdopterin cofactor binding
AXW76_RS24795	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS24800	COG4689	acetoacetate decarboxylase
AXW76_RS24845	COG1309	transcriptional regulator
AXW76_RS24890	COG2205	protein histidine kinase activity
AXW76_RS24890	COG0784	Response regulator, receiver
AXW76_RS24930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXW76_RS24960	COG4372	Transposase
AXW76_RS24965	COG4372	Transposase
AXW76_RS25075	COG1335	isochorismatase
AXW76_RS25095	COG4191	Histidine kinase
AXW76_RS25235	COG2801	Transposase and inactivated derivatives
AXW76_RS25240	COG2267	carboxylic ester hydrolase activity
AXW76_RS25270	COG0604	alcohol dehydrogenase
AXW76_RS25285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXW76_RS25320	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXW76_RS25325	COG4372	Transposase
AXW76_RS25360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXW76_RS25365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXW76_RS25375	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AXW76_RS25415	COG5489	Protein of unknown function (DUF736)
AXW76_RS25420	COG4974	Belongs to the 'phage' integrase family
AXW76_RS25425	COG0582	viral genome integration into host DNA
AXW76_RS25430	COG4974	Belongs to the 'phage' integrase family
AXW76_RS25435	COG5489	Protein of unknown function (DUF736)
AXW76_RS25480	COG2801	Transposase and inactivated derivatives
AXW76_RS25500	COG1192	Involved in chromosome partitioning
AXW76_RS25545	COG4962	Type ii secretion system protein e
AXW76_RS25555	COG4584	PFAM Integrase catalytic
AXW76_RS25560	COG0247	lactate metabolic process
AXW76_RS25575	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AXW76_RS25595	COG2801	Transposase and inactivated derivatives
AXW76_RS25635	COG5489	Protein of unknown function (DUF736)
AXW76_RS25640	COG4974	Belongs to the 'phage' integrase family
AXW76_RS25645	COG0582	viral genome integration into host DNA
AXW76_RS25650	COG4974	Belongs to the 'phage' integrase family
AXW76_RS25655	COG5489	Protein of unknown function (DUF736)
AXW76_RS25665	COG2801	Transposase and inactivated derivatives
AXW76_RS25680	COG4372	Transposase
AXW76_RS25685	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXW76_RS25730	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AXW76_RS25750	COG1278	Cold shock
AXW76_RS25780	COG4584	PFAM Integrase catalytic
AXW76_RS25790	COG2801	Transposase and inactivated derivatives
AXW76_RS25830	COG1278	Cold shock
AXW76_RS25840	COG3344	reverse transcriptase
AXW76_RS25860	COG4372	Transposase
AXW76_RS25870	COG2801	Transposase and inactivated derivatives
AXW76_RS25875	COG3344	reverse transcriptase
AXW76_RS25900	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AXW76_RS25930	COG3474	cytochrome
AXW76_RS25935	COG0277	FAD linked oxidase domain protein
AXW76_RS25945	COG0277	FAD linked oxidase domain protein
AXW76_RS25950	COG0247	lactate metabolic process
AXW76_RS25965	COG4178	(ABC) transporter
AXW76_RS25970	COG1620	l-lactate permease
AXW76_RS25985	COG0459	protein refolding
AXW76_RS25990	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AXW76_RS26005	COG1388	LysM domain
AXW76_RS26005	COG1376	ErfK ybiS ycfS ynhG family protein
AXW76_RS26010	COG3416	Protein conserved in bacteria
AXW76_RS26025	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AXW76_RS26030	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AXW76_RS26055	COG0312	modulator of DNA gyrase
AXW76_RS26075	COG1519	Transferase
AXW76_RS26080	COG1663	tetraacyldisaccharide 4'-kinase activity
AXW76_RS26120	COG1570	exodeoxyribonuclease VII activity
AXW76_RS26140	COG0151	Belongs to the GarS family
AXW76_RS26145	COG0596	Alpha beta hydrolase
AXW76_RS26150	COG0590	tRNA wobble adenosine to inosine editing
AXW76_RS26155	COG1187	pseudouridine synthase activity
AXW76_RS26160	COG0742	ribosomal rna small subunit methyltransferase
AXW76_RS26165	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AXW76_RS26210	COG0612	Peptidase, M16
AXW76_RS26215	COG0612	Peptidase, M16
AXW76_RS26225	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AXW76_RS26230	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AXW76_RS26235	COG0196	riboflavin kinase activity
AXW76_RS26240	COG0745	RESPONSE REGULATOR receiver
AXW76_RS26250	COG2200	EAL domain
AXW76_RS26250	COG2771	luxR family
AXW76_RS26255	COG1295	ribonuclease BN
AXW76_RS26265	COG2890	protein-(glutamine-N5) methyltransferase activity
AXW76_RS26270	COG0314	molybdopterin synthase activity
AXW76_RS26280	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AXW76_RS26285	COG0322	excinuclease ABC activity
AXW76_RS26290	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AXW76_RS26295	COG1278	Cold shock
AXW76_RS26300	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AXW76_RS26330	COG0745	RESPONSE REGULATOR receiver
AXW76_RS26335	COG1846	Transcriptional regulator
AXW76_RS26350	COG0124	histidyl-tRNA synthetase
AXW76_RS26355	COG1942	4-Oxalocrotonate Tautomerase
AXW76_RS26365	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AXW76_RS26375	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AXW76_RS26380	COG1181	Belongs to the D-alanine--D-alanine ligase family
AXW76_RS26390	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AXW76_RS26410	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AXW76_RS26425	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AXW76_RS26430	COG0193	aminoacyl-tRNA hydrolase activity
AXW76_RS26435	COG0012	GTP binding
AXW76_RS26445	COG2030	dehydratase
AXW76_RS26485	COG0556	nucleotide-excision repair
AXW76_RS26500	COG0583	DNA-binding transcription factor activity
AXW76_RS26535	COG0667	Aldo Keto reductase
AXW76_RS26555	COG0625	glutathione transferase activity
AXW76_RS26560	COG0436	Aminotransferase
AXW76_RS26570	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AXW76_RS26580	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AXW76_RS26605	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AXW76_RS26790	COG1278	Cold shock
AXW76_RS26835	COG2205	protein histidine kinase activity
AXW76_RS26840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXW76_RS26855	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXW76_RS26860	COG4372	Transposase
AXW76_RS26870	COG0183	Belongs to the thiolase family
AXW76_RS26875	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXW76_RS26895	COG0625	glutathione transferase activity
AXW76_RS26910	COG2223	nitrite transmembrane transporter activity
AXW76_RS26950	COG5489	Protein of unknown function (DUF736)
AXW76_RS26955	COG4974	Belongs to the 'phage' integrase family
AXW76_RS26960	COG5489	Protein of unknown function (DUF736)
AXW76_RS27000	COG1192	Involved in chromosome partitioning
AXW76_RS27050	COG4962	Type ii secretion system protein e
AXW76_RS27055	COG3838	Conjugal transfer protein Trbc
AXW76_RS27065	COG3451	type IV secretory pathway VirB4
AXW76_RS27085	COG3701	Conjugal transfer protein
AXW76_RS27095	COG2948	multi-organism process
AXW76_RS27115	COG1126	abc transporter atp-binding protein
AXW76_RS27120	COG0765	amino acid transport
AXW76_RS27130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW76_RS27145	COG1012	belongs to the aldehyde dehydrogenase family
AXW76_RS27175	COG0765	amino acid transport
AXW76_RS27180	COG0765	amino acid transport
AXW76_RS27185	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AXW76_RS27215	COG1431	PFAM Stem cell self-renewal protein Piwi
AXW76_RS27240	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXW76_RS27245	COG4372	Transposase
AXW76_RS27280	COG3409	Peptidoglycan-binding domain 1 protein
AXW76_RS27295	COG2801	Transposase and inactivated derivatives
AXW76_RS27310	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AXW76_RS27340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXW76_RS27345	COG0583	DNA-binding transcription factor activity
AXW76_RS27350	COG0492	ferredoxin-NADP+ reductase activity
AXW76_RS27355	COG1522	sequence-specific DNA binding
AXW76_RS27360	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AXW76_RS27365	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AXW76_RS27400	COG0505	Belongs to the CarA family
AXW76_RS27415	COG0596	Alpha beta hydrolase
AXW76_RS27420	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AXW76_RS27465	COG0640	Transcriptional regulator
AXW76_RS27485	COG1280	lysine exporter protein (LysE YggA)
AXW76_RS27525	COG0358	DNA primase activity
AXW76_RS27530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AXW76_RS27570	COG1280	lysine exporter protein (LysE YggA)
AXW76_RS27575	COG3706	GGDEF domain
AXW76_RS27590	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AXW76_RS27595	COG0564	pseudouridine synthase activity
AXW76_RS27615	COG1615	UPF0182 protein
AXW76_RS27660	COG0628	permease
AXW76_RS27690	COG0651	ATP synthesis coupled electron transport
AXW76_RS27695	COG1006	Multisubunit Na H antiporter MnhC subunit
AXW76_RS27715	COG1320	monovalent cation:proton antiporter activity
AXW76_RS27745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXW76_RS27760	COG2235	arginine
AXW76_RS27780	COG2197	response regulator
AXW76_RS27790	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AXW76_RS27820	COG1309	transcriptional regulator
AXW76_RS27845	COG0318	PFAM AMP-dependent synthetase and ligase
AXW76_RS27855	COG3284	Transcriptional regulator
AXW76_RS27860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXW76_RS27870	COG3734	2-keto-3-deoxy-galactonokinase
AXW76_RS27875	COG0800	Aldolase
AXW76_RS27925	COG2205	protein histidine kinase activity
AXW76_RS27930	COG0402	S-adenosylhomocysteine deaminase activity
AXW76_RS27940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXW76_RS27950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXW76_RS27970	COG1960	acyl-CoA dehydrogenase activity
AXW76_RS27975	COG1960	acyl-CoA dehydrogenase activity
AXW76_RS27980	COG1024	Enoyl-CoA hydratase
AXW76_RS27985	COG1704	LemA family
AXW76_RS27990	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AXW76_RS28015	COG0506	proline dehydrogenase activity
AXW76_RS28015	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AXW76_RS28015	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AXW76_RS28025	COG1278	Cold shock
AXW76_RS28050	COG3768	UPF0283 membrane protein
AXW76_RS28055	COG3106	COG3106 Predicted ATPase
AXW76_RS28060	COG1272	protein, Hemolysin III
AXW76_RS28065	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS28075	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS28085	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
AXW76_RS28095	COG1960	acyl-CoA dehydrogenase activity
AXW76_RS28100	COG0583	DNA-binding transcription factor activity
AXW76_RS28120	COG0501	Belongs to the peptidase M48B family
AXW76_RS28125	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AXW76_RS28140	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AXW76_RS28150	COG2226	methyltransferase
AXW76_RS28160	COG1376	ErfK ybiS ycfS ynhG family protein
AXW76_RS28160	COG1388	LysM domain
AXW76_RS28165	COG0028	Belongs to the TPP enzyme family
AXW76_RS28175	COG1376	ErfK ybiS ycfS ynhG family protein
AXW76_RS28210	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AXW76_RS28445	COG0784	Response regulator, receiver
AXW76_RS28445	COG2198	Histidine kinase
AXW76_RS28445	COG0643	Histidine kinase
AXW76_RS28450	COG0835	chemotaxis
AXW76_RS28455	COG2198	Histidine kinase
AXW76_RS28455	COG0784	Response regulator, receiver
AXW76_RS28455	COG0643	Histidine kinase
AXW76_RS28475	COG0754	glutathionylspermidine amidase activity
AXW76_RS28500	COG1595	DNA-templated transcription, initiation
AXW76_RS28525	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AXW76_RS28570	COG1309	transcriptional regulator
AXW76_RS28575	COG2080	2 iron, 2 sulfur cluster binding
AXW76_RS28580	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AXW76_RS28590	COG3620	sequence-specific DNA binding
AXW76_RS28595	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AXW76_RS28600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXW76_RS28615	COG0765	amino acid transport
AXW76_RS28620	COG1126	abc transporter atp-binding protein
AXW76_RS28625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXW76_RS28635	COG0405	Gamma-glutamyltransferase
AXW76_RS28640	COG1024	Enoyl-CoA hydratase
AXW76_RS28665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXW76_RS28685	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AXW76_RS28760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXW76_RS28785	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AXW76_RS28870	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AXW76_RS28890	COG2205	protein histidine kinase activity
AXW76_RS28890	COG2202	Pas domain
AXW76_RS28945	COG0746	molybdenum cofactor guanylyltransferase activity
AXW76_RS28955	COG1763	Mo-molybdopterin cofactor biosynthetic process
AXW76_RS28970	COG2223	nitrite transmembrane transporter activity
AXW76_RS28980	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AXW76_RS28985	COG3383	formate dehydrogenase (NAD+) activity
AXW76_RS28990	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AXW76_RS29000	COG0431	NADPH-dependent FMN reductase
AXW76_RS29000	COG1053	succinate dehydrogenase
AXW76_RS29000	COG3976	FMN-binding domain protein
AXW76_RS29040	COG5002	protein histidine kinase activity
AXW76_RS29040	COG5001	Diguanylate cyclase
AXW76_RS29040	COG3447	MASE1 domain protein
AXW76_RS29045	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AXW76_RS29060	COG0346	lactoylglutathione lyase activity
AXW76_RS29070	COG0583	DNA-binding transcription factor activity
AXW76_RS29080	COG3485	protocatechuate 3,4-dioxygenase
AXW76_RS29120	COG0745	RESPONSE REGULATOR receiver
AXW76_RS29125	COG0643	Histidine kinase
AXW76_RS29125	COG2198	Histidine kinase
AXW76_RS29130	COG0835	chemotaxis
AXW76_RS29140	COG0835	chemotaxis
AXW76_RS29145	COG0840	transmembrane signaling receptor activity
AXW76_RS29155	COG2201	protein-glutamate methylesterase activity
AXW76_RS29205	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AXW76_RS29215	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AXW76_RS29235	COG3206	protein involved in exopolysaccharide biosynthesis
AXW76_RS29235	COG0489	protein tyrosine kinase activity
AXW76_RS29260	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AXW76_RS29260	COG2755	lipolytic protein G-D-S-L family
AXW76_RS29270	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AXW76_RS29275	COG2244	polysaccharide biosynthetic process
AXW76_RS29280	COG1045	serine acetyltransferase
AXW76_RS29295	COG0438	transferase activity, transferring glycosyl groups
AXW76_RS29340	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AXW76_RS29365	COG3474	cytochrome
AXW76_RS29385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXW76_RS29395	COG5001	Diguanylate cyclase
AXW76_RS29395	COG3300	MHYT domain
AXW76_RS29405	COG1309	transcriptional regulator
AXW76_RS29415	COG0181	hydroxymethylbilane synthase activity
AXW76_RS29420	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AXW76_RS29430	COG5001	Diguanylate cyclase
AXW76_RS29430	COG2203	Gaf domain
AXW76_RS29430	COG3706	GGDEF domain
AXW76_RS29430	COG4251	negative regulation of phosphorylation
AXW76_RS29435	COG2900	Belongs to the SlyX family
AXW76_RS29440	COG1054	Belongs to the UPF0176 family
AXW76_RS29445	COG0405	Gamma-glutamyltransferase
AXW76_RS29455	COG3237	CsbD-like
AXW76_RS29490	COG4191	Histidine kinase
AXW76_RS29490	COG0784	Response regulator, receiver
AXW76_RS29505	COG2885	chlorophyll binding
AXW76_RS29505	COG3047	cAMP biosynthetic process
AXW76_RS29550	COG1309	transcriptional regulator
AXW76_RS29570	COG1024	Enoyl-CoA hydratase
AXW76_RS29570	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXW76_RS29580	COG1607	acyl-coa hydrolase
AXW76_RS29600	COG1349	DNA-binding transcription factor activity
AXW76_RS29620	COG3842	ATPase activity
AXW76_RS29625	COG3842	ATPase activity
AXW76_RS29635	COG0395	ABC-type sugar transport system, permease component
AXW76_RS29655	COG2197	response regulator
AXW76_RS29660	COG1902	pentaerythritol trinitrate reductase activity
AXW76_RS29685	COG0501	Belongs to the peptidase M48B family
AXW76_RS29735	COG0494	nUDIX hydrolase
AXW76_RS29740	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AXW76_RS29745	COG4771	TonB-dependent receptor
AXW76_RS29770	COG0714	Associated with various cellular activities
AXW76_RS29830	COG0408	coproporphyrinogen oxidase activity
AXW76_RS29840	COG0602	queuosine metabolic process
AXW76_RS29845	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AXW76_RS29850	COG0723	plastoquinol--plastocyanin reductase activity
AXW76_RS29855	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AXW76_RS29855	COG2857	Cytochrome c1
AXW76_RS29875	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AXW76_RS29895	COG1704	LemA family
AXW76_RS29905	COG1196	nuclear chromosome segregation
AXW76_RS29910	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AXW76_RS29910	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AXW76_RS29940	COG0625	glutathione transferase activity
AXW76_RS29970	COG0625	glutathione transferase activity
AXW76_RS29980	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AXW76_RS29985	COG2321	neutral zinc metallopeptidase
AXW76_RS29990	COG0521	Mo-molybdopterin cofactor biosynthetic process
AXW76_RS29995	COG1846	Transcriptional regulator
AXW76_RS29995	COG0456	acetyltransferase
AXW76_RS30010	COG0574	Belongs to the PEP-utilizing enzyme family
AXW76_RS30010	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AXW76_RS30025	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AXW76_RS30030	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AXW76_RS30045	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AXW76_RS30055	COG1573	uracil-dna glycosylase
AXW76_RS30070	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AXW76_RS30080	COG1280	lysine exporter protein (LysE YggA)
AXW76_RS30085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AXW76_RS30095	COG0142	geranyltranstransferase activity
AXW76_RS30120	COG0752	glycyl-tRNA synthetase alpha subunit
AXW76_RS30125	COG0751	glycine-tRNA ligase activity
AXW76_RS30135	COG0574	Belongs to the PEP-utilizing enzyme family
AXW76_RS30135	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AXW76_RS30150	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AXW76_RS30155	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AXW76_RS30165	COG0604	alcohol dehydrogenase
AXW76_RS30210	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AXW76_RS30215	COG0519	Catalyzes the synthesis of GMP from XMP
AXW76_RS30220	COG0354	folic acid binding
AXW76_RS30225	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AXW76_RS30230	COG2897	thiosulfate sulfurtransferase activity
AXW76_RS30235	COG1595	DNA-templated transcription, initiation
AXW76_RS30270	COG2135	peptidase activity
AXW76_RS30285	COG0494	nUDIX hydrolase
AXW76_RS30295	COG0277	FAD linked oxidase domain protein
AXW76_RS30300	COG0009	L-threonylcarbamoyladenylate synthase
AXW76_RS30345	COG4584	PFAM Integrase catalytic
AXW76_RS30355	COG2801	Transposase and inactivated derivatives
AXW76_RS30370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXW76_RS30425	COG1309	transcriptional regulator
AXW76_RS30430	COG2814	Major facilitator Superfamily
AXW76_RS30450	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AXW76_RS30470	COG1850	ribulose-bisphosphate carboxylase activity
AXW76_RS30475	COG4451	ribulose bisphosphate carboxylase, small
AXW76_RS30495	COG3300	MHYT domain
AXW76_RS30495	COG5001	Diguanylate cyclase
AXW76_RS30560	COG4999	Histidine kinase
AXW76_RS30560	COG2205	protein histidine kinase activity
AXW76_RS30560	COG3850	Histidine kinase
AXW76_RS30560	COG3437	response regulator, receiver
AXW76_RS30650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXW76_RS30660	COG0475	glutathione-regulated potassium exporter activity
AXW76_RS30660	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AXW76_RS30670	COG1960	acyl-CoA dehydrogenase activity
AXW76_RS30685	COG0318	PFAM AMP-dependent synthetase and ligase
AXW76_RS30705	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS30710	COG0259	pyridoxamine-phosphate oxidase activity
AXW76_RS30735	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AXW76_RS30750	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AXW76_RS30760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXW76_RS30775	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AXW76_RS30780	COG1993	acr, cog1993
AXW76_RS30785	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AXW76_RS30790	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AXW76_RS30810	COG1024	Enoyl-CoA hydratase
AXW76_RS30835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AXW76_RS30840	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AXW76_RS30850	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AXW76_RS30855	COG1722	exodeoxyribonuclease VII activity
AXW76_RS30860	COG0123	including yeast histone deacetylase and acetoin utilization protein
AXW76_RS30865	COG4085	toxin activity
AXW76_RS30865	COG0737	Belongs to the 5'-nucleotidase family
AXW76_RS30865	COG1525	nuclease
AXW76_RS30875	COG2223	nitrite transmembrane transporter activity
AXW76_RS30880	COG1960	acyl-CoA dehydrogenase activity
AXW76_RS30900	COG0556	nucleotide-excision repair
AXW76_RS30930	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AXW76_RS31105	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AXW76_RS31105	COG1672	PFAM Archaeal ATPase
AXW76_RS31170	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXW76_RS31175	COG4372	Transposase
AXW76_RS31190	COG3119	arylsulfatase activity
AXW76_RS31240	COG1879	ABC-type sugar transport system periplasmic component
AXW76_RS31245	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXW76_RS31255	COG1129	ABC transporter
AXW76_RS31270	COG0277	FAD linked oxidase domain protein
AXW76_RS31275	COG3485	protocatechuate 3,4-dioxygenase
AXW76_RS31285	COG0402	S-adenosylhomocysteine deaminase activity
AXW76_RS31300	COG0583	DNA-binding transcription factor activity
AXW76_RS31320	COG1012	belongs to the aldehyde dehydrogenase family
AXW76_RS31355	COG1132	(ABC) transporter
AXW76_RS31375	COG0741	lytic transglycosylase activity
AXW76_RS31425	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AXW76_RS31435	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AXW76_RS31455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXW76_RS31460	COG1053	succinate dehydrogenase
AXW76_RS31475	COG1335	isochorismatase
AXW76_RS31495	COG3833	ABC-type maltose transport systems, permease component
AXW76_RS31500	COG1175	transmembrane transport
AXW76_RS31505	COG1653	transport
AXW76_RS31510	COG3258	Cytochrome c
AXW76_RS31530	COG0446	pyridine nucleotide-disulphide oxidoreductase
AXW76_RS31535	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AXW76_RS31535	COG2010	Cytochrome c
AXW76_RS31560	COG1032	radical SAM domain protein
AXW76_RS31565	COG2814	Major facilitator Superfamily
AXW76_RS31570	COG0473	3-isopropylmalate dehydrogenase activity
AXW76_RS31615	COG2264	protein methyltransferase activity
AXW76_RS31625	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS31630	COG4106	trans-aconitate 2-methyltransferase activity
AXW76_RS31645	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AXW76_RS31650	COG0438	transferase activity, transferring glycosyl groups
AXW76_RS31655	COG1132	(ABC) transporter
AXW76_RS31675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AXW76_RS31680	COG0745	RESPONSE REGULATOR receiver
AXW76_RS31685	COG4566	intracellular signal transduction
AXW76_RS31690	COG4191	Histidine kinase
AXW76_RS31700	COG0517	IMP dehydrogenase activity
AXW76_RS31700	COG0516	GMP reductase activity
AXW76_RS31705	COG3278	Belongs to the heme-copper respiratory oxidase family
AXW76_RS31720	COG2010	Cytochrome c
AXW76_RS31735	COG2217	Heavy metal translocating P-type atpase
AXW76_RS31765	COG0583	DNA-binding transcription factor activity
AXW76_RS31780	COG0297	glycogen (starch) synthase activity
AXW76_RS31795	COG0473	3-isopropylmalate dehydrogenase activity
AXW76_RS31805	COG1024	Enoyl-CoA hydratase
AXW76_RS31810	COG2989	Protein conserved in bacteria
AXW76_RS31830	COG1396	sequence-specific DNA binding
AXW76_RS31845	COG0785	Cytochrome C biogenesis protein
AXW76_RS31850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AXW76_RS31855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXW76_RS31865	COG2207	Transcriptional regulator
AXW76_RS31870	COG2202	Pas domain
AXW76_RS31870	COG3920	Histidine kinase
AXW76_RS31890	COG3485	protocatechuate 3,4-dioxygenase
AXW76_RS31895	COG0515	serine threonine protein kinase
AXW76_RS31905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXW76_RS31910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW76_RS31915	COG1116	anion transmembrane transporter activity
AXW76_RS31925	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXW76_RS31925	COG1017	nitric oxide dioxygenase activity
AXW76_RS31930	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AXW76_RS31935	COG0243	molybdopterin cofactor binding
AXW76_RS31940	COG0656	L-ascorbic acid biosynthetic process
AXW76_RS31960	COG4372	Transposase
AXW76_RS31970	COG1063	alcohol dehydrogenase
AXW76_RS31980	COG1522	sequence-specific DNA binding
AXW76_RS31985	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AXW76_RS32000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXW76_RS32045	COG0129	dihydroxy-acid dehydratase activity
AXW76_RS32075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXW76_RS32080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXW76_RS32090	COG1309	transcriptional regulator
AXW76_RS32095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW76_RS32115	COG0673	inositol 2-dehydrogenase activity
AXW76_RS32155	COG0659	secondary active sulfate transmembrane transporter activity
AXW76_RS32170	COG4372	Transposase
AXW76_RS32175	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXW76_RS32205	COG1980	fructose-bisphosphate aldolase activity
AXW76_RS32220	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AXW76_RS32240	COG3119	arylsulfatase activity
AXW76_RS32245	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AXW76_RS32250	COG2124	cytochrome p450
AXW76_RS32260	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
AXW76_RS32260	COG0028	Belongs to the TPP enzyme family
AXW76_RS32265	COG1309	transcriptional regulator
AXW76_RS32270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXW76_RS32275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXW76_RS32290	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AXW76_RS32310	COG0747	negative chemotaxis
AXW76_RS32315	COG4608	Belongs to the ABC transporter superfamily
AXW76_RS32320	COG0444	Belongs to the ABC transporter superfamily
AXW76_RS32340	COG0444	Belongs to the ABC transporter superfamily
AXW76_RS32345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW76_RS32355	COG4166	transmembrane transport
AXW76_RS32375	COG2267	carboxylic ester hydrolase activity
AXW76_RS32420	COG2733	membrane
AXW76_RS32425	COG0596	Alpha beta hydrolase
AXW76_RS32430	COG3327	negative regulation of DNA-templated transcription, initiation
AXW76_RS32435	COG3396	Phenylacetate-CoA oxygenase
AXW76_RS32440	COG3460	Phenylacetate-CoA oxygenase
AXW76_RS32445	COG3396	Phenylacetate-CoA oxygenase
AXW76_RS32450	COG2151	metal-sulfur cluster biosynthetic enzyme
AXW76_RS32455	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXW76_RS32460	COG2050	protein possibly involved in aromatic compounds catabolism
AXW76_RS32495	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AXW76_RS32500	COG0477	Major facilitator Superfamily
AXW76_RS32525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW76_RS32530	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AXW76_RS32540	COG4597	amino acid ABC transporter
AXW76_RS32545	COG0765	amino acid transport
AXW76_RS32555	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS32560	COG0473	3-isopropylmalate dehydrogenase activity
AXW76_RS32565	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AXW76_RS32570	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AXW76_RS32580	COG0583	DNA-binding transcription factor activity
AXW76_RS32585	COG4336	lyase activity
AXW76_RS32615	COG0235	Class ii aldolase
AXW76_RS32620	COG2084	Dehydrogenase
AXW76_RS32625	COG3622	Belongs to the hyi family
AXW76_RS32630	COG3395	kinase activity
AXW76_RS32640	COG0840	transmembrane signaling receptor activity
AXW76_RS32645	COG0840	transmembrane signaling receptor activity
AXW76_RS32645	COG0840	transmembrane signaling receptor activity
AXW76_RS32665	COG2070	2-Nitropropane dioxygenase
AXW76_RS32670	COG2072	flavoprotein involved in K transport
AXW76_RS32675	COG0625	glutathione transferase activity
AXW76_RS32690	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS32695	COG1024	Enoyl-CoA hydratase
AXW76_RS32710	COG1024	Enoyl-CoA hydratase
AXW76_RS32715	COG1960	acyl-CoA dehydrogenase activity
AXW76_RS32730	COG1024	Enoyl-CoA hydratase
AXW76_RS32740	COG1024	Enoyl-CoA hydratase
AXW76_RS32755	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AXW76_RS32760	COG3386	PFAM SMP-30 Gluconolaconase
AXW76_RS32765	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS32800	COG3145	DNA-N1-methyladenine dioxygenase activity
AXW76_RS32810	COG0028	Belongs to the TPP enzyme family
AXW76_RS32815	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXW76_RS32835	COG3971	2-oxopent-4-enoate hydratase activity
AXW76_RS32840	COG1846	Transcriptional regulator
AXW76_RS32855	COG2721	sulfolactate sulfo-lyase activity
AXW76_RS32930	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AXW76_RS32940	COG4303	Ethanolamine ammonia lyase large subunit
AXW76_RS32950	COG4302	ethanolamine ammonia-lyase activity
AXW76_RS32975	COG1562	ergosterol biosynthetic process
AXW76_RS32980	COG1562	ergosterol biosynthetic process
AXW76_RS32985	COG1233	COG1233 Phytoene dehydrogenase and related
AXW76_RS32990	COG1657	PFAM Prenyltransferase squalene oxidase
AXW76_RS32995	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AXW76_RS33005	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AXW76_RS33070	COG1473	amidohydrolase
AXW76_RS33075	COG0306	phosphate transporter
AXW76_RS33095	COG0587	DNA-directed DNA polymerase activity
AXW76_RS33100	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS33110	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXW76_RS33140	COG1024	Enoyl-CoA hydratase
AXW76_RS33205	COG1703	isobutyryl-CoA mutase activity
AXW76_RS33250	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AXW76_RS33260	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AXW76_RS33275	COG0433	COG0433 Predicted ATPase
AXW76_RS33305	COG4957	zinc ion binding
AXW76_RS33310	COG2166	iron-sulfur cluster assembly
AXW76_RS33320	COG2205	protein histidine kinase activity
AXW76_RS33355	COG0583	DNA-binding transcription factor activity
AXW76_RS33445	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AXW76_RS33455	COG0765	amino acid transport
AXW76_RS33460	COG0765	amino acid transport
AXW76_RS33465	COG1126	abc transporter atp-binding protein
AXW76_RS33500	COG4372	Transposase
AXW76_RS33510	COG1335	isochorismatase
AXW76_RS33530	COG2983	Belongs to the UPF0260 family
AXW76_RS33535	COG0477	Major facilitator Superfamily
AXW76_RS33545	COG4191	Histidine kinase
AXW76_RS33545	COG0784	Response regulator, receiver
AXW76_RS33550	COG0028	Belongs to the TPP enzyme family
AXW76_RS33575	COG0463	Glycosyl transferase, family 2
AXW76_RS33590	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AXW76_RS33595	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AXW76_RS33600	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AXW76_RS33620	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AXW76_RS33645	COG4235	cytochrome complex assembly
AXW76_RS33650	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AXW76_RS33655	COG1138	Cytochrome C-type biogenesis protein
AXW76_RS33675	COG0745	RESPONSE REGULATOR receiver
AXW76_RS33680	COG2205	protein histidine kinase activity
AXW76_RS33685	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AXW76_RS33695	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AXW76_RS33700	COG3383	formate dehydrogenase (NAD+) activity
AXW76_RS33715	COG0583	DNA-binding transcription factor activity
AXW76_RS33720	COG2202	Pas domain
AXW76_RS33720	COG2205	protein histidine kinase activity
AXW76_RS33725	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AXW76_RS33730	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS33730	COG3321	synthase
AXW76_RS33730	COG0604	alcohol dehydrogenase
AXW76_RS33755	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXW76_RS33760	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AXW76_RS33780	COG0443	Heat shock 70 kDa protein
AXW76_RS33795	COG1278	Cold shock
AXW76_RS33815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXW76_RS33825	COG1802	Transcriptional regulator
AXW76_RS33860	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AXW76_RS33870	COG3622	Belongs to the hyi family
AXW76_RS33875	COG2084	Dehydrogenase
AXW76_RS33900	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AXW76_RS33920	COG1982	Orn Lys Arg decarboxylase major
AXW76_RS33925	COG1522	sequence-specific DNA binding
AXW76_RS33930	COG0686	Belongs to the AlaDH PNT family
AXW76_RS33935	COG2072	flavoprotein involved in K transport
AXW76_RS33940	COG1309	transcriptional regulator
AXW76_RS33980	COG2855	membrane
AXW76_RS33985	COG1116	anion transmembrane transporter activity
AXW76_RS33990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW76_RS33995	COG4521	taurine ABC transporter
AXW76_RS34000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AXW76_RS34020	COG1053	succinate dehydrogenase
AXW76_RS34045	COG1129	ABC transporter
AXW76_RS34050	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXW76_RS34055	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXW76_RS34075	COG3386	PFAM SMP-30 Gluconolaconase
AXW76_RS34080	COG4213	ABC transporter substrate-binding protein
AXW76_RS34085	COG1129	ABC transporter
AXW76_RS34090	COG4214	carbohydrate transport
AXW76_RS34095	COG1845	cytochrome c oxidase, subunit III
AXW76_RS34110	COG3256	nitric oxide reductase
AXW76_RS34115	COG0714	Associated with various cellular activities
AXW76_RS34125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AXW76_RS34150	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS34180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW76_RS34190	COG4608	Belongs to the ABC transporter superfamily
AXW76_RS34195	COG0747	negative chemotaxis
AXW76_RS34225	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXW76_RS34230	COG4372	Transposase
AXW76_RS34250	COG3842	ATPase activity
AXW76_RS34255	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AXW76_RS34260	COG1177	transmembrane transport
AXW76_RS34265	COG1176	ABC-type spermidine putrescine transport system, permease component I
AXW76_RS34275	COG0400	carboxylic ester hydrolase activity
AXW76_RS34280	COG0346	lactoylglutathione lyase activity
AXW76_RS34285	COG0583	DNA-binding transcription factor activity
AXW76_RS34315	COG0778	Nitroreductase
AXW76_RS34320	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AXW76_RS34330	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AXW76_RS34340	COG1492	cobalamin metabolic process
AXW76_RS34385	COG2099	Precorrin-6x reductase
AXW76_RS34400	COG2875	Belongs to the precorrin methyltransferase family
AXW76_RS34405	COG1797	cobyrinic acid a,c-diamide synthase activity
AXW76_RS34410	COG1648	precorrin-2 dehydrogenase activity
AXW76_RS34410	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AXW76_RS34425	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AXW76_RS34445	COG0154	amidase activity
AXW76_RS34455	COG2351	hydroxyisourate hydrolase activity
AXW76_RS34465	COG1176	ABC-type spermidine putrescine transport system, permease component I
AXW76_RS34470	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AXW76_RS34475	COG3842	ATPase activity
AXW76_RS34480	COG0154	amidase activity
AXW76_RS34490	COG1802	Transcriptional regulator
AXW76_RS34500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW76_RS34505	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AXW76_RS34520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW76_RS34525	COG2030	dehydratase
AXW76_RS34530	COG4670	ketone body catabolic process
AXW76_RS34535	COG1960	acyl-CoA dehydrogenase activity
AXW76_RS34545	COG1609	Transcriptional regulator
AXW76_RS34550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXW76_RS34555	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXW76_RS34575	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXW76_RS34590	COG0765	amino acid transport
AXW76_RS34595	COG1126	abc transporter atp-binding protein
AXW76_RS34605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXW76_RS34610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW76_RS34620	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXW76_RS34625	COG0235	Class ii aldolase
AXW76_RS34645	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AXW76_RS34680	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AXW76_RS34685	COG0318	PFAM AMP-dependent synthetase and ligase
AXW76_RS34695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXW76_RS34715	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS34720	COG2072	flavoprotein involved in K transport
AXW76_RS34725	COG0747	negative chemotaxis
AXW76_RS34730	COG0601	transmembrane transport
AXW76_RS34735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW76_RS34745	COG0747	negative chemotaxis
AXW76_RS34750	COG0601	transmembrane transport
AXW76_RS34755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW76_RS34760	COG0444	Belongs to the ABC transporter superfamily
AXW76_RS34765	COG4608	Belongs to the ABC transporter superfamily
AXW76_RS34855	COG0445	tRNA wobble uridine modification
AXW76_RS34870	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AXW76_RS34875	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AXW76_RS34880	COG3386	PFAM SMP-30 Gluconolaconase
AXW76_RS34890	COG3618	amidohydrolase
AXW76_RS34940	COG5564	TIM-barrel signal transduction protein
AXW76_RS34985	COG1175	transmembrane transport
AXW76_RS34990	COG0395	ABC-type sugar transport system, permease component
AXW76_RS34995	COG0673	inositol 2-dehydrogenase activity
AXW76_RS35005	COG1609	Transcriptional regulator
AXW76_RS35015	COG0477	Major facilitator Superfamily
AXW76_RS35045	COG0318	PFAM AMP-dependent synthetase and ligase
AXW76_RS35050	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS35100	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXW76_RS35120	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AXW76_RS35125	COG0596	Alpha beta hydrolase
AXW76_RS35135	COG1846	Transcriptional regulator
AXW76_RS35175	COG1764	response to oxidative stress
AXW76_RS35215	COG0251	oxidation-reduction process
AXW76_RS35230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXW76_RS35270	COG1960	acyl-CoA dehydrogenase activity
AXW76_RS35275	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS35305	COG0628	permease
AXW76_RS35320	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AXW76_RS35325	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AXW76_RS35335	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AXW76_RS35340	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AXW76_RS35355	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXW76_RS35380	COG4566	intracellular signal transduction
AXW76_RS35400	COG2985	domain, Protein
AXW76_RS35455	COG4191	Histidine kinase
AXW76_RS35460	COG3064	Membrane
AXW76_RS35490	COG0489	protein tyrosine kinase activity
AXW76_RS35530	COG4964	Belongs to the GSP D family
AXW76_RS35555	COG4584	PFAM Integrase catalytic
AXW76_RS35565	COG0640	Transcriptional regulator
AXW76_RS35575	COG0785	Cytochrome C biogenesis protein
AXW76_RS35615	COG0737	Belongs to the 5'-nucleotidase family
AXW76_RS35620	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AXW76_RS35645	COG2391	methyltransferase activity
AXW76_RS35650	COG2391	methyltransferase activity
AXW76_RS35660	COG0640	Transcriptional regulator
AXW76_RS35665	COG3181	Tripartite tricarboxylate transporter family receptor
AXW76_RS35725	COG1024	Enoyl-CoA hydratase
AXW76_RS35730	COG0477	Major facilitator Superfamily
AXW76_RS35740	COG3395	kinase activity
AXW76_RS35745	COG0235	Class ii aldolase
AXW76_RS35750	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AXW76_RS35755	COG3842	ATPase activity
AXW76_RS35765	COG3833	ABC-type maltose transport systems, permease component
AXW76_RS35820	COG3547	Transposase (IS116 IS110 IS902 family)
AXW76_RS35825	COG2205	protein histidine kinase activity
AXW76_RS35830	COG0745	RESPONSE REGULATOR receiver
AXW76_RS35860	COG2188	Transcriptional regulator
AXW76_RS35870	COG1175	transmembrane transport
AXW76_RS35875	COG0395	ABC-type sugar transport system, permease component
AXW76_RS35895	COG1461	Dihydroxyacetone kinase
AXW76_RS35900	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AXW76_RS35920	COG2376	Dihydroxyacetone kinase
AXW76_RS35955	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXW76_RS35960	COG4372	Transposase
AXW76_RS35975	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AXW76_RS35975	COG4797	methyltransferase
AXW76_RS36030	COG1716	ATPase activity
AXW76_RS36040	COG2885	chlorophyll binding
AXW76_RS36135	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AXW76_RS36150	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AXW76_RS36160	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS36175	COG1053	succinate dehydrogenase
AXW76_RS36180	COG1053	succinate dehydrogenase
AXW76_RS36185	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AXW76_RS36195	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXW76_RS36230	COG1053	succinate dehydrogenase
AXW76_RS36245	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS36275	COG1595	DNA-templated transcription, initiation
AXW76_RS36280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AXW76_RS36310	COG1749	Flagellar hook protein flgE
AXW76_RS36345	COG1136	(ABC) transporter
AXW76_RS36345	COG0577	efflux transmembrane transporter activity
AXW76_RS36370	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AXW76_RS36375	COG2801	Transposase and inactivated derivatives
AXW76_RS36395	COG4213	ABC transporter substrate-binding protein
AXW76_RS36405	COG4214	carbohydrate transport
AXW76_RS36425	COG1175	transmembrane transport
AXW76_RS36435	COG0395	ABC-type sugar transport system, permease component
AXW76_RS36445	COG3540	Alkaline phosphatase
AXW76_RS36455	COG1063	alcohol dehydrogenase
AXW76_RS36465	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AXW76_RS36470	COG1653	transport
AXW76_RS36475	COG0395	ABC-type sugar transport system, permease component
AXW76_RS36480	COG1175	transmembrane transport
AXW76_RS36505	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXW76_RS36510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXW76_RS36515	COG1301	dicarboxylic acid transport
AXW76_RS36530	COG0281	malic enzyme
AXW76_RS36530	COG0280	phosphate acetyltransferase
AXW76_RS36535	COG1252	NADH dehydrogenase
AXW76_RS36540	COG1271	oxidase subunit
AXW76_RS36550	COG2801	Transposase and inactivated derivatives
AXW76_RS36555	COG1294	oxidase, subunit
AXW76_RS36565	COG2204	response regulator
AXW76_RS36570	COG3243	poly(R)-hydroxyalkanoic acid synthase
AXW76_RS36580	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AXW76_RS36605	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AXW76_RS36610	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AXW76_RS36615	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
AXW76_RS36620	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AXW76_RS36640	COG2202	Pas domain
AXW76_RS36640	COG2205	protein histidine kinase activity
AXW76_RS36645	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AXW76_RS36650	COG2084	Dehydrogenase
AXW76_RS36665	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AXW76_RS36675	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AXW76_RS36685	COG0745	RESPONSE REGULATOR receiver
AXW76_RS36690	COG5002	protein histidine kinase activity
AXW76_RS36705	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AXW76_RS36710	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AXW76_RS36720	COG0546	phosphoglycolate phosphatase activity
AXW76_RS36725	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AXW76_RS36760	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AXW76_RS36765	COG0121	glutamine amidotransferase
AXW76_RS36775	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXW76_RS36775	COG1017	nitric oxide dioxygenase activity
AXW76_RS36795	COG0861	Integral membrane protein TerC family
AXW76_RS36810	COG0583	DNA-binding transcription factor activity
AXW76_RS36825	COG1012	belongs to the aldehyde dehydrogenase family
AXW76_RS36840	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AXW76_RS36845	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AXW76_RS36870	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AXW76_RS36875	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AXW76_RS36895	COG0215	cysteine-tRNA ligase activity
AXW76_RS36905	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AXW76_RS36920	COG5265	(ABC) transporter
AXW76_RS36925	COG0688	phosphatidylethanolamine metabolic process
AXW76_RS36930	COG1183	phosphatidylcholine synthase activity
AXW76_RS36945	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS36950	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AXW76_RS36960	COG3158	transport of potassium into the cell
AXW76_RS36965	COG3158	transport of potassium into the cell
AXW76_RS36975	COG0436	Aminotransferase
AXW76_RS36980	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AXW76_RS36990	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AXW76_RS37000	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AXW76_RS37005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AXW76_RS37030	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AXW76_RS37035	COG1285	pathogenesis
AXW76_RS37055	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AXW76_RS37055	COG2010	Cytochrome c
AXW76_RS37060	COG2080	2 iron, 2 sulfur cluster binding
AXW76_RS37100	COG1846	Transcriptional regulator
AXW76_RS37155	COG3618	amidohydrolase
AXW76_RS37165	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AXW76_RS37220	COG1289	transmembrane transporter activity
AXW76_RS37230	COG1566	PFAM secretion protein HlyD family protein
AXW76_RS37240	COG0318	PFAM AMP-dependent synthetase and ligase
AXW76_RS37250	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AXW76_RS37330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXW76_RS37335	COG1309	transcriptional regulator
AXW76_RS37345	COG2814	Major facilitator Superfamily
AXW76_RS37350	COG1012	belongs to the aldehyde dehydrogenase family
AXW76_RS37355	COG1802	Transcriptional regulator
AXW76_RS37365	COG0477	Major facilitator Superfamily
AXW76_RS37370	COG0402	S-adenosylhomocysteine deaminase activity
AXW76_RS37380	COG1234	tRNA 3'-trailer cleavage
AXW76_RS37400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXW76_RS37405	COG0277	FAD linked oxidase domain protein
AXW76_RS37410	COG3395	kinase activity
AXW76_RS37415	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AXW76_RS37420	COG1454	alcohol dehydrogenase
AXW76_RS37440	COG3547	Transposase (IS116 IS110 IS902 family)
AXW76_RS37445	COG4584	PFAM Integrase catalytic
AXW76_RS37480	COG2801	Transposase and inactivated derivatives
AXW76_RS37495	COG5507	3-demethylubiquinone-9 3-methyltransferase
AXW76_RS37515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXW76_RS37530	COG4774	siderophore transport
AXW76_RS37535	COG3128	pkhd-type hydroxylase
AXW76_RS37545	COG0848	biopolymer transport protein
AXW76_RS37560	COG1994	Peptidase M50
AXW76_RS37570	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AXW76_RS37575	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS37580	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS37585	COG0129	dihydroxy-acid dehydratase activity
AXW76_RS37590	COG1609	Transcriptional regulator
AXW76_RS37595	COG3842	ATPase activity
AXW76_RS37610	COG3833	ABC-type maltose transport systems, permease component
AXW76_RS37615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXW76_RS37620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXW76_RS37625	COG0800	Aldolase
AXW76_RS37630	COG0183	Belongs to the thiolase family
AXW76_RS37640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXW76_RS37645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AXW76_RS37655	COG2186	Transcriptional regulator
AXW76_RS37660	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AXW76_RS37685	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AXW76_RS37685	COG2066	Belongs to the glutaminase family
AXW76_RS37700	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AXW76_RS37710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AXW76_RS37730	COG0625	glutathione transferase activity
AXW76_RS37765	COG2271	Major facilitator Superfamily
AXW76_RS37770	COG0183	Belongs to the thiolase family
AXW76_RS37775	COG1024	Enoyl-CoA hydratase
AXW76_RS37800	COG1960	acyl-CoA dehydrogenase activity
AXW76_RS37875	COG4584	PFAM Integrase catalytic
AXW76_RS38015	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS38025	COG2814	Major facilitator Superfamily
AXW76_RS38030	COG0583	DNA-binding transcription factor activity
AXW76_RS38045	COG1671	Belongs to the UPF0178 family
AXW76_RS38065	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AXW76_RS38080	COG2130	NADP-dependent
AXW76_RS38090	COG1609	Transcriptional regulator
AXW76_RS38100	COG0251	oxidation-reduction process
AXW76_RS38115	COG0765	amino acid transport
AXW76_RS38120	COG0765	amino acid transport
AXW76_RS38150	COG1278	Cold shock
AXW76_RS38165	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AXW76_RS38165	COG0519	Catalyzes the synthesis of GMP from XMP
AXW76_RS38175	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS38180	COG0583	DNA-binding transcription factor activity
AXW76_RS38190	COG1510	regulation of RNA biosynthetic process
AXW76_RS38215	COG1012	belongs to the aldehyde dehydrogenase family
AXW76_RS38235	COG2207	Transcriptional regulator
AXW76_RS38250	COG0242	peptide deformylase activity
AXW76_RS38270	COG2814	Major facilitator Superfamily
AXW76_RS38285	COG1764	response to oxidative stress
AXW76_RS38290	COG1846	Transcriptional regulator
AXW76_RS38305	COG1301	dicarboxylic acid transport
AXW76_RS38310	COG1802	Transcriptional regulator
AXW76_RS38370	COG0625	glutathione transferase activity
AXW76_RS38380	COG0625	glutathione transferase activity
AXW76_RS38390	COG1309	transcriptional regulator
AXW76_RS38395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXW76_RS38395	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXW76_RS38400	COG1393	Belongs to the ArsC family
AXW76_RS38435	COG1392	Phosphate transport regulator
AXW76_RS38440	COG0306	phosphate transporter
AXW76_RS38465	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AXW76_RS38470	COG0318	PFAM AMP-dependent synthetase and ligase
AXW76_RS38485	COG1160	GTP binding
AXW76_RS38510	COG0300	oxidoreductase activity
AXW76_RS38515	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AXW76_RS38520	COG1286	toxin biosynthetic process
AXW76_RS38570	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AXW76_RS38575	COG0305	Participates in initiation and elongation during chromosome replication
AXW76_RS38580	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AXW76_RS38600	COG0359	binds to the 23S rRNA
AXW76_RS38610	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AXW76_RS38615	COG0360	Binds together with S18 to 16S ribosomal RNA
AXW76_RS38630	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AXW76_RS38640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AXW76_RS38645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AXW76_RS38655	COG1561	YicC-like family, N-terminal region
AXW76_RS38660	COG0194	GDP metabolic process
AXW76_RS38700	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AXW76_RS38705	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AXW76_RS38725	COG0795	lipopolysaccharide-transporting ATPase activity
AXW76_RS38730	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AXW76_RS38760	COG3162	membrane
AXW76_RS38765	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AXW76_RS38775	COG2176	DNA-directed DNA polymerase activity
AXW76_RS38780	COG0488	(ABC) transporter
AXW76_RS38795	COG0105	UTP biosynthetic process
AXW76_RS38800	COG0861	Integral membrane protein TerC family
AXW76_RS38805	COG0248	Ppx GppA phosphatase
AXW76_RS38810	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AXW76_RS38820	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AXW76_RS38825	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AXW76_RS38830	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AXW76_RS38835	COG1278	Cold shock
AXW76_RS38865	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AXW76_RS38870	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AXW76_RS38895	COG1175	transmembrane transport
AXW76_RS38910	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AXW76_RS38920	COG0281	malic enzyme
AXW76_RS38920	COG0280	phosphate acetyltransferase
AXW76_RS38940	COG0386	Belongs to the glutathione peroxidase family
AXW76_RS38950	COG3045	CreA protein
AXW76_RS38980	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AXW76_RS38995	COG3483	tryptophan 2,3-dioxygenase activity
AXW76_RS39030	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS39035	COG2365	Tyrosine phosphatase family
AXW76_RS39050	COG0174	glutamine synthetase
AXW76_RS39100	COG2207	Transcriptional regulator
AXW76_RS39125	COG0488	(ABC) transporter
AXW76_RS39150	COG0657	acetylesterase activity
AXW76_RS39160	COG0840	transmembrane signaling receptor activity
AXW76_RS39180	COG2207	Transcriptional regulator
AXW76_RS39230	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AXW76_RS39260	COG1309	transcriptional regulator
AXW76_RS39270	COG0850	regulation of cytokinetic process
AXW76_RS39275	COG2894	cell division
AXW76_RS39280	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AXW76_RS39300	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS39315	COG1376	ErfK ybiS ycfS ynhG family protein
AXW76_RS39350	COG1309	transcriptional regulator
AXW76_RS39375	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AXW76_RS39425	COG2824	Alkylphosphonate utilization operon protein PhnA
AXW76_RS39500	COG4372	Transposase
AXW76_RS39505	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AXW76_RS39510	COG0697	spore germination
AXW76_RS39515	COG0784	Response regulator, receiver
AXW76_RS39515	COG4191	Histidine kinase
AXW76_RS39550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AXW76_RS39560	COG0657	acetylesterase activity
AXW76_RS39570	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AXW76_RS39575	COG0745	RESPONSE REGULATOR receiver
AXW76_RS39580	COG0784	Response regulator, receiver
AXW76_RS39585	COG5002	protein histidine kinase activity
AXW76_RS39590	COG0439	Biotin carboxylase
AXW76_RS39595	COG0511	ligase activity, forming carbon-carbon bonds
AXW76_RS39600	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AXW76_RS39620	COG0436	Aminotransferase
AXW76_RS39625	COG1268	BioY protein
AXW76_RS39630	COG1301	dicarboxylic acid transport
AXW76_RS39650	COG2271	Major facilitator Superfamily
AXW76_RS39670	COG0860	N-Acetylmuramoyl-L-alanine amidase
AXW76_RS39695	COG0697	spore germination
AXW76_RS39720	COG0438	transferase activity, transferring glycosyl groups
AXW76_RS39740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXW76_RS39755	COG0739	heme binding
AXW76_RS39780	COG2259	Doxx family
AXW76_RS39790	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AXW76_RS39795	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AXW76_RS39800	COG0625	glutathione transferase activity
AXW76_RS39815	COG2945	thiolester hydrolase activity
AXW76_RS39830	COG1104	cysteine desulfurase activity
AXW76_RS39835	COG0719	Fe-S assembly protein
AXW76_RS39840	COG0396	ATPase activity
AXW76_RS39845	COG0719	Fe-S assembly protein
AXW76_RS39850	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AXW76_RS39855	COG2151	metal-sulfur cluster biosynthetic enzyme
AXW76_RS39860	COG0316	Belongs to the HesB IscA family
AXW76_RS39870	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AXW76_RS39880	COG0513	Belongs to the DEAD box helicase family
AXW76_RS39910	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS39925	COG0187	DNA topoisomerase II activity
AXW76_RS39930	COG0586	Pfam SNARE associated Golgi protein
AXW76_RS39955	COG3243	poly(R)-hydroxyalkanoic acid synthase
AXW76_RS39965	COG0436	Aminotransferase
AXW76_RS39975	COG1494	fructose-1,6-bisphosphatase
AXW76_RS39995	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AXW76_RS40005	COG1802	Transcriptional regulator
AXW76_RS40015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXW76_RS40035	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AXW76_RS40045	COG0840	transmembrane signaling receptor activity
AXW76_RS40050	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AXW76_RS40105	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AXW76_RS40110	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AXW76_RS40125	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AXW76_RS40220	COG3750	Belongs to the UPF0335 family
AXW76_RS40300	COG0616	signal peptide processing
AXW76_RS40470	COG0625	glutathione transferase activity
AXW76_RS40485	COG4372	Transposase
AXW76_RS40510	COG2801	Transposase and inactivated derivatives
AXW76_RS40515	COG2267	carboxylic ester hydrolase activity
AXW76_RS40535	COG0776	regulation of translation
AXW76_RS40555	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AXW76_RS40620	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AXW76_RS40685	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AXW76_RS40770	COG1074	ATP-dependent DNA helicase activity
AXW76_RS40860	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AXW76_RS41005	COG1793	dna ligase
AXW76_RS41110	COG3118	belongs to the thioredoxin family
AXW76_RS41245	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AXW76_RS41345	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AXW76_RS41355	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AXW76_RS41450	COG0582	viral genome integration into host DNA
AXW76_RS41470	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXW76_RS41475	COG4372	Transposase
AXW76_RS41480	COG2801	Transposase and inactivated derivatives
AXW76_RS41490	COG4372	Transposase
AXW76_RS41520	COG0546	phosphoglycolate phosphatase activity
AXW76_RS41530	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AXW76_RS41550	COG0629	single-stranded DNA binding
AXW76_RS41560	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AXW76_RS41565	COG3158	transport of potassium into the cell
AXW76_RS41575	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AXW76_RS41595	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AXW76_RS41610	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AXW76_RS41620	COG1309	transcriptional regulator
AXW76_RS41655	COG0697	spore germination
AXW76_RS41675	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AXW76_RS41700	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AXW76_RS41725	COG0628	permease
AXW76_RS41745	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AXW76_RS41760	COG4584	PFAM Integrase catalytic
AXW76_RS41785	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXW76_RS41795	COG4372	Transposase
AXW76_RS41810	COG4372	Transposase
AXW76_RS41850	COG2723	6-phospho-beta-galactosidase activity
AXW76_RS41870	COG0484	heat shock protein binding
AXW76_RS41940	COG0516	GMP reductase activity
AXW76_RS41940	COG0517	IMP dehydrogenase activity
AXW76_RS41960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXW76_RS41970	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AXW76_RS41970	COG0617	tRNA 3'-terminal CCA addition
AXW76_RS41970	COG0517	IMP dehydrogenase activity
AXW76_RS41975	COG0071	Belongs to the small heat shock protein (HSP20) family
AXW76_RS41980	COG0459	protein refolding
AXW76_RS41995	COG1136	(ABC) transporter
AXW76_RS42000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AXW76_RS42070	COG1796	DNA polymerase
AXW76_RS42070	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AXW76_RS42075	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AXW76_RS42075	COG0517	IMP dehydrogenase activity
AXW76_RS42075	COG0617	tRNA 3'-terminal CCA addition
AXW76_RS42080	COG0589	response to stress
AXW76_RS42105	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AXW76_RS42110	COG1278	Cold shock
AXW76_RS42165	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AXW76_RS42175	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AXW76_RS42190	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AXW76_RS42205	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AXW76_RS42225	COG0667	Aldo Keto reductase
AXW76_RS42235	COG1278	Cold shock
AXW76_RS42285	COG0679	Auxin Efflux Carrier
AXW76_RS42290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXW76_RS42295	COG1183	phosphatidylcholine synthase activity
AXW76_RS42300	COG1253	flavin adenine dinucleotide binding
AXW76_RS42310	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AXW76_RS42330	COG0789	Transcriptional regulator
AXW76_RS42335	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AXW76_RS42345	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AXW76_RS42360	COG3707	response regulator
AXW76_RS42365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXW76_RS42370	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AXW76_RS42375	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AXW76_RS42380	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AXW76_RS42395	COG0473	3-isopropylmalate dehydrogenase activity
AXW76_RS42395	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AXW76_RS42450	COG1175	transmembrane transport
AXW76_RS42490	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AXW76_RS42490	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AXW76_RS42505	COG0444	Belongs to the ABC transporter superfamily
AXW76_RS42515	COG0601	transmembrane transport
AXW76_RS42520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW76_RS42540	COG0129	dihydroxy-acid dehydratase activity
AXW76_RS42600	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AXW76_RS42610	COG1686	Belongs to the peptidase S11 family
AXW76_RS42635	COG0084	hydrolase, TatD family'
AXW76_RS42640	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AXW76_RS42640	COG0321	lipoyl(octanoyl) transferase activity
AXW76_RS42645	COG0318	PFAM AMP-dependent synthetase and ligase
AXW76_RS42655	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXW76_RS42705	COG2011	ABC-type metal ion transport system permease component
AXW76_RS42715	COG0471	metal ion transport
AXW76_RS42740	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AXW76_RS42745	COG3956	TIGRFAM MazG family protein
AXW76_RS42750	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AXW76_RS42755	COG1923	regulation of RNA biosynthetic process
AXW76_RS42760	COG2204	response regulator
AXW76_RS42765	COG5000	phosphorelay sensor kinase activity
AXW76_RS42785	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AXW76_RS42785	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AXW76_RS42790	COG1546	Belongs to the CinA family
AXW76_RS42790	COG1058	Belongs to the CinA family
AXW76_RS42815	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AXW76_RS42820	COG2863	cytochrome
AXW76_RS42825	COG2867	negative regulation of translational initiation
AXW76_RS42830	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AXW76_RS42835	COG2094	Belongs to the DNA glycosylase MPG family
AXW76_RS42840	COG0525	valine-tRNA ligase activity
AXW76_RS42855	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AXW76_RS42880	COG0251	oxidation-reduction process
AXW76_RS42895	COG1126	abc transporter atp-binding protein
AXW76_RS42930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXW76_RS42965	COG1126	abc transporter atp-binding protein
AXW76_RS42970	COG0765	amino acid transport
AXW76_RS42975	COG4597	amino acid ABC transporter
AXW76_RS42980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW76_RS42985	COG0626	cystathionine gamma-synthase activity
AXW76_RS42990	COG1283	sodium-dependent phosphate transmembrane transporter activity
AXW76_RS43005	COG0463	Glycosyl transferase, family 2
AXW76_RS43010	COG0671	phosphoesterase, PA-phosphatase related
AXW76_RS43025	COG2373	Large extracellular alpha-helical protein
AXW76_RS43065	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXW76_RS43090	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXW76_RS43090	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AXW76_RS43095	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXW76_RS43100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXW76_RS43110	COG4770	biotin carboxylase activity
AXW76_RS43115	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AXW76_RS43120	COG1960	acyl-CoA dehydrogenase activity
AXW76_RS43135	COG1522	sequence-specific DNA binding
AXW76_RS43160	COG4372	Transposase
AXW76_RS43165	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXW76_RS43285	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AXW76_RS43335	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AXW76_RS43345	COG2340	Cysteine-rich secretory protein family
AXW76_RS43360	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AXW76_RS43380	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AXW76_RS43385	COG1862	Preprotein translocase
AXW76_RS43395	COG3119	arylsulfatase activity
AXW76_RS43410	COG3119	arylsulfatase activity
AXW76_RS43415	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AXW76_RS43425	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AXW76_RS43435	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AXW76_RS43450	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AXW76_RS43455	COG0805	protein transport
AXW76_RS43460	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AXW76_RS43465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AXW76_RS43470	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AXW76_RS43475	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AXW76_RS43480	COG1472	Belongs to the glycosyl hydrolase 3 family
AXW76_RS43490	COG0018	arginyl-trna synthetase
AXW76_RS43495	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AXW76_RS43505	COG0784	Response regulator, receiver
AXW76_RS43505	COG2198	Histidine kinase
AXW76_RS43505	COG5002	protein histidine kinase activity
AXW76_RS43510	COG0708	Exodeoxyribonuclease III
AXW76_RS43515	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AXW76_RS43520	COG0129	dihydroxy-acid dehydratase activity
AXW76_RS43570	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXW76_RS43575	COG4372	Transposase
AXW76_RS43585	COG3344	reverse transcriptase
AXW76_RS43590	COG4372	Transposase
AXW76_RS43615	COG1793	dna ligase
AXW76_RS43625	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AXW76_RS43670	COG2197	response regulator
AXW76_RS43685	COG4297	protein containing double-stranded beta helix domain
AXW76_RS43690	COG0671	phosphoesterase, PA-phosphatase related
AXW76_RS43695	COG0723	plastoquinol--plastocyanin reductase activity
AXW76_RS43710	COG2080	2 iron, 2 sulfur cluster binding
AXW76_RS43715	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AXW76_RS43720	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AXW76_RS43750	COG0071	Belongs to the small heat shock protein (HSP20) family
AXW76_RS43755	COG0071	Belongs to the small heat shock protein (HSP20) family
AXW76_RS43770	COG0745	RESPONSE REGULATOR receiver
AXW76_RS43800	COG0438	transferase activity, transferring glycosyl groups
AXW76_RS43815	COG0071	Belongs to the small heat shock protein (HSP20) family
AXW76_RS43820	COG0071	Belongs to the small heat shock protein (HSP20) family
AXW76_RS43825	COG0071	Belongs to the small heat shock protein (HSP20) family
AXW76_RS43845	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AXW76_RS43860	COG0071	Belongs to the small heat shock protein (HSP20) family
AXW76_RS43875	COG0071	Belongs to the small heat shock protein (HSP20) family
AXW76_RS43880	COG0071	Belongs to the small heat shock protein (HSP20) family
AXW76_RS43885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXW76_RS43925	COG4584	PFAM Integrase catalytic
AXW76_RS44015	COG4191	Histidine kinase
AXW76_RS44020	COG4566	intracellular signal transduction
AXW76_RS44025	COG4566	intracellular signal transduction
AXW76_RS44035	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AXW76_RS44040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXW76_RS44050	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXW76_RS44070	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AXW76_RS44075	COG1012	belongs to the aldehyde dehydrogenase family
AXW76_RS44090	COG0431	NADPH-dependent FMN reductase
AXW76_RS44100	COG1917	Cupin 2, conserved barrel domain protein
AXW76_RS44100	COG4977	sequence-specific DNA binding
AXW76_RS44105	COG4221	oxidoreductase activity
AXW76_RS44125	COG0148	phosphopyruvate hydratase activity
AXW76_RS44135	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AXW76_RS44145	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AXW76_RS44145	COG2066	Belongs to the glutaminase family
AXW76_RS44155	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AXW76_RS44165	COG0745	RESPONSE REGULATOR receiver
AXW76_RS44175	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AXW76_RS44180	COG0504	CTP synthase activity
AXW76_RS44190	COG0149	triose-phosphate isomerase activity
AXW76_RS44195	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AXW76_RS44200	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AXW76_RS44205	COG0134	indole-3-glycerol-phosphate synthase activity
AXW76_RS44210	COG0315	cyclic pyranopterin monophosphate synthase activity
AXW76_RS44275	COG0793	Belongs to the peptidase S41A family
AXW76_RS44280	COG1304	FMN binding
AXW76_RS44285	COG1011	Hydrolase
AXW76_RS44300	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AXW76_RS44335	COG0477	Major facilitator Superfamily
AXW76_RS44365	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AXW76_RS44370	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AXW76_RS44375	COG0372	Belongs to the citrate synthase family
AXW76_RS44395	COG1175	transmembrane transport
AXW76_RS44400	COG0395	ABC-type sugar transport system, permease component
AXW76_RS44410	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS44415	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AXW76_RS44425	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AXW76_RS44435	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AXW76_RS44440	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AXW76_RS44445	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AXW76_RS44450	COG0750	zinc metalloprotease
AXW76_RS44455	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AXW76_RS44465	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AXW76_RS44470	COG0233	cytoplasmic translational termination
AXW76_RS44475	COG0528	UMP kinase activity
AXW76_RS44480	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AXW76_RS44485	COG0052	Belongs to the universal ribosomal protein uS2 family
AXW76_RS44505	COG0288	reversible hydration of carbon dioxide
AXW76_RS44535	COG2814	Major facilitator Superfamily
AXW76_RS44540	COG0024	Methionine aminopeptidase
AXW76_RS44560	COG1136	(ABC) transporter
AXW76_RS44570	COG0442	prolyl-tRNA aminoacylation
AXW76_RS44615	COG1129	ABC transporter
AXW76_RS44620	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXW76_RS44635	COG0583	DNA-binding transcription factor activity
AXW76_RS44650	COG4608	Belongs to the ABC transporter superfamily
AXW76_RS44655	COG0444	Belongs to the ABC transporter superfamily
AXW76_RS44660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW76_RS44675	COG4584	PFAM Integrase catalytic
AXW76_RS44685	COG0747	negative chemotaxis
AXW76_RS44705	COG0346	lactoylglutathione lyase activity
AXW76_RS44720	COG1007	ATP synthesis coupled electron transport
AXW76_RS44735	COG0713	ATP synthesis coupled electron transport
AXW76_RS44745	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXW76_RS44750	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AXW76_RS44760	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AXW76_RS44770	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AXW76_RS44780	COG0649	NAD binding
AXW76_RS44790	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXW76_RS44805	COG4774	siderophore transport
AXW76_RS44835	COG2195	Cleaves the N-terminal amino acid of tripeptides
AXW76_RS44845	COG1595	DNA-templated transcription, initiation
AXW76_RS44870	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXW76_RS44905	COG2755	lipolytic protein G-D-S-L family
AXW76_RS44905	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AXW76_RS44920	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AXW76_RS44925	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AXW76_RS44935	COG0544	peptidyl-prolyl cis-trans isomerase activity
AXW76_RS44950	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AXW76_RS44950	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AXW76_RS44955	COG0347	Belongs to the P(II) protein family
AXW76_RS44960	COG0174	glutamine synthetase
AXW76_RS44965	COG0252	asparaginase activity
AXW76_RS44970	COG0330	HflC and HflK could
AXW76_RS44990	COG3038	cytochrome b561
AXW76_RS45000	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AXW76_RS45025	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AXW76_RS45030	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AXW76_RS45040	COG1024	Enoyl-CoA hydratase
AXW76_RS45060	COG1612	heme a metabolic process
AXW76_RS45085	COG0438	transferase activity, transferring glycosyl groups
AXW76_RS45100	COG1846	Transcriptional regulator
AXW76_RS45105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXW76_RS45110	COG3268	Saccharopine dehydrogenase
AXW76_RS45170	COG0657	acetylesterase activity
AXW76_RS45180	COG0135	phosphoribosylanthranilate isomerase activity
AXW76_RS45240	COG0776	regulation of translation
AXW76_RS45245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AXW76_RS45250	COG0416	fatty acid biosynthetic process
AXW76_RS45275	COG2801	Transposase and inactivated derivatives
AXW76_RS45285	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AXW76_RS45290	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AXW76_RS45295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AXW76_RS45300	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AXW76_RS45310	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AXW76_RS45310	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AXW76_RS45315	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AXW76_RS45345	COG0113	porphobilinogen synthase activity
AXW76_RS45355	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AXW76_RS45380	COG1914	H( )-stimulated, divalent metal cation uptake system
AXW76_RS45390	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AXW76_RS45410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXW76_RS45450	COG0747	negative chemotaxis
AXW76_RS45455	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AXW76_RS45465	COG1381	Involved in DNA repair and RecF pathway recombination
AXW76_RS45480	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AXW76_RS45485	COG0571	ribonuclease III activity
AXW76_RS45490	COG0681	Belongs to the peptidase S26 family
AXW76_RS45495	COG0736	holo-[acyl-carrier-protein] synthase activity
AXW76_RS45500	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AXW76_RS45510	COG1758	RNA polymerase activity
AXW76_RS45530	COG1970	mechanosensitive ion channel activity
AXW76_RS45535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXW76_RS45540	COG0741	lytic transglycosylase activity
AXW76_RS45550	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AXW76_RS45580	COG4584	PFAM Integrase catalytic
AXW76_RS45625	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AXW76_RS45635	COG0154	amidase activity
AXW76_RS45645	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AXW76_RS45660	COG0583	DNA-binding transcription factor activity
AXW76_RS45670	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AXW76_RS45685	COG1960	acyl-CoA dehydrogenase activity
AXW76_RS45695	COG0540	Belongs to the ATCase OTCase family
AXW76_RS45705	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AXW76_RS45720	COG0758	DNA mediated transformation
AXW76_RS45725	COG1733	regulation of RNA biosynthetic process
AXW76_RS45730	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AXW76_RS45740	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS45770	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AXW76_RS45775	COG0557	exoribonuclease II activity
AXW76_RS45800	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AXW76_RS45830	COG0784	Response regulator, receiver
AXW76_RS45840	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AXW76_RS45850	COG0494	nUDIX hydrolase
AXW76_RS45880	COG0537	adenosine 5'-monophosphoramidase activity
AXW76_RS45885	COG1720	tRNA m6t6A37 methyltransferase activity
AXW76_RS45930	COG1482	cell wall glycoprotein biosynthetic process
AXW76_RS45960	COG0667	Aldo Keto reductase
AXW76_RS45970	COG2814	Major facilitator Superfamily
AXW76_RS45985	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AXW76_RS46010	COG1275	C4-dicarboxylate transporter malic acid transport protein
AXW76_RS46025	COG1192	Involved in chromosome partitioning
AXW76_RS46030	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AXW76_RS46075	COG0656	L-ascorbic acid biosynthetic process
AXW76_RS46085	COG2239	Acts as a magnesium transporter
AXW76_RS46120	COG0321	lipoyl(octanoyl) transferase activity
AXW76_RS46140	COG1090	epimerase
AXW76_RS46160	COG1254	Belongs to the acylphosphatase family
AXW76_RS46165	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AXW76_RS46170	COG4770	biotin carboxylase activity
AXW76_RS46180	COG5001	Diguanylate cyclase
AXW76_RS46220	COG2271	Major facilitator Superfamily
AXW76_RS46230	COG4948	Mandelate Racemase Muconate Lactonizing
AXW76_RS46235	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS46240	COG1063	alcohol dehydrogenase
AXW76_RS46255	COG2197	response regulator
AXW76_RS46265	COG1414	Transcriptional regulator
AXW76_RS46275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXW76_RS46280	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXW76_RS46325	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS46365	COG4566	intracellular signal transduction
AXW76_RS46375	COG0577	efflux transmembrane transporter activity
AXW76_RS46375	COG1136	(ABC) transporter
AXW76_RS46380	COG0577	efflux transmembrane transporter activity
AXW76_RS46380	COG1136	(ABC) transporter
AXW76_RS46385	COG2197	response regulator
AXW76_RS46405	COG0450	alkyl hydroperoxide reductase
AXW76_RS46415	COG0415	Belongs to the DNA photolyase family
AXW76_RS46520	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS46525	COG2030	dehydratase
AXW76_RS46555	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AXW76_RS46555	COG2010	Cytochrome c
AXW76_RS46560	COG2860	membrane
AXW76_RS46615	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AXW76_RS46640	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AXW76_RS46850	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AXW76_RS46905	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AXW76_RS46935	COG0085	RNA polymerase activity
AXW76_RS47010	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AXW76_RS47130	COG1028	Short-chain dehydrogenase reductase Sdr
AXW76_RS47405	COG0784	Response regulator, receiver
AXW76_RS47405	COG4191	Histidine kinase
AXW76_RS47950	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AXW76_RS48000	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AXW76_RS48020	COG0085	RNA polymerase activity
AXW76_RS48060	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AXW76_RS48060	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AXW76_RS48285	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AXW76_RS48300	COG2274	protein secretion by the type I secretion system
AXW76_RS48615	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates