locus-tag	class	description
BKD09_RS00030	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BKD09_RS00030	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BKD09_RS00055	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BKD09_RS00080	COG2801	Transposase and inactivated derivatives
BKD09_RS00090	COG2010	Cytochrome c
BKD09_RS00105	COG1484	DNA-dependent DNA replication
BKD09_RS00110	COG4716	Myosin-crossreactive antigen
BKD09_RS00150	COG2963	transposase activity
BKD09_RS00155	COG3436	PFAM IS66 Orf2 family protein
BKD09_RS00160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKD09_RS00165	COG0765	amino acid transport
BKD09_RS00170	COG1396	sequence-specific DNA binding
BKD09_RS00220	COG1192	Involved in chromosome partitioning
BKD09_RS00255	COG5489	Protein of unknown function (DUF736)
BKD09_RS00270	COG1278	Cold shock
BKD09_RS00275	COG2226	methyltransferase
BKD09_RS00320	COG2925	Exonuclease
BKD09_RS00395	COG4941	Belongs to the sigma-70 factor family
BKD09_RS00410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKD09_RS00415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKD09_RS00440	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BKD09_RS00450	COG1116	anion transmembrane transporter activity
BKD09_RS00455	COG1253	flavin adenine dinucleotide binding
BKD09_RS00465	COG0069	glutamate synthase activity
BKD09_RS00485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKD09_RS00490	COG1301	dicarboxylic acid transport
BKD09_RS00495	COG2130	NADP-dependent
BKD09_RS00525	COG0625	glutathione transferase activity
BKD09_RS00550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BKD09_RS00555	COG0583	DNA-binding transcription factor activity
BKD09_RS00565	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BKD09_RS00575	COG1024	Enoyl-CoA hydratase
BKD09_RS00580	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BKD09_RS00590	COG1960	acyl-CoA dehydrogenase activity
BKD09_RS00605	COG0747	negative chemotaxis
BKD09_RS00610	COG3964	amidohydrolase
BKD09_RS00645	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BKD09_RS00670	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BKD09_RS00680	COG2261	transglycosylase associated protein
BKD09_RS00695	COG1960	acyl-CoA dehydrogenase activity
BKD09_RS00700	COG1024	Enoyl-CoA hydratase
BKD09_RS00710	COG1024	Enoyl-CoA hydratase
BKD09_RS00730	COG3474	cytochrome
BKD09_RS00735	COG0477	Major facilitator Superfamily
BKD09_RS00740	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BKD09_RS00745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BKD09_RS00750	COG1845	cytochrome c oxidase, subunit III
BKD09_RS00755	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BKD09_RS00770	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BKD09_RS00775	COG0583	DNA-binding transcription factor activity
BKD09_RS00790	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BKD09_RS00795	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BKD09_RS00810	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BKD09_RS00845	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BKD09_RS00870	COG1902	pentaerythritol trinitrate reductase activity
BKD09_RS00900	COG0586	Pfam SNARE associated Golgi protein
BKD09_RS00905	COG0372	Belongs to the citrate synthase family
BKD09_RS00910	COG0372	Belongs to the citrate synthase family
BKD09_RS00930	COG2801	Transposase and inactivated derivatives
BKD09_RS00930	COG3415	Transposase
BKD09_RS00935	COG4536	flavin adenine dinucleotide binding
BKD09_RS00940	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BKD09_RS00945	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BKD09_RS00955	COG4974	Belongs to the 'phage' integrase family
BKD09_RS00960	COG0825	malonyl-CoA metabolic process
BKD09_RS00965	COG3034	peptidoglycan biosynthetic process
BKD09_RS00975	COG3842	ATPase activity
BKD09_RS01010	COG0653	protein targeting
BKD09_RS01015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BKD09_RS01020	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BKD09_RS01035	COG1040	competence protein
BKD09_RS01045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BKD09_RS01060	COG2827	Endonuclease containing a URI domain
BKD09_RS01065	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BKD09_RS01075	COG0527	aspartate kinase activity
BKD09_RS01085	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BKD09_RS01130	COG2890	protein-(glutamine-N5) methyltransferase activity
BKD09_RS01145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKD09_RS01155	COG0697	spore germination
BKD09_RS01170	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
BKD09_RS01185	COG0657	acetylesterase activity
BKD09_RS01215	COG1522	sequence-specific DNA binding
BKD09_RS01220	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BKD09_RS01225	COG0514	ATP-dependent DNA helicase (RecQ)
BKD09_RS01240	COG2873	o-acetylhomoserine
BKD09_RS01245	COG0154	amidase activity
BKD09_RS01260	COG0667	Aldo Keto reductase
BKD09_RS01265	COG2814	Major facilitator Superfamily
BKD09_RS01270	COG0583	DNA-binding transcription factor activity
BKD09_RS01285	COG0154	amidase activity
BKD09_RS01300	COG0318	PFAM AMP-dependent synthetase and ligase
BKD09_RS01310	COG2124	cytochrome p450
BKD09_RS01315	COG2814	Major facilitator Superfamily
BKD09_RS01335	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS01345	COG2207	Transcriptional regulator
BKD09_RS01365	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BKD09_RS01370	COG0732	type I restriction modification DNA specificity domain
BKD09_RS01375	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BKD09_RS01450	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BKD09_RS01455	COG1877	trehalose-phosphatase activity
BKD09_RS01460	COG0477	Major facilitator Superfamily
BKD09_RS01495	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKD09_RS01505	COG1522	sequence-specific DNA binding
BKD09_RS01510	COG3813	Protein conserved in bacteria
BKD09_RS01520	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BKD09_RS01535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKD09_RS01540	COG1846	Transcriptional regulator
BKD09_RS01575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKD09_RS01610	COG5001	Diguanylate cyclase
BKD09_RS01645	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BKD09_RS01670	COG2706	6-phosphogluconolactonase activity
BKD09_RS01695	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BKD09_RS01705	COG1696	Membrane protein involved in D-alanine export
BKD09_RS01720	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BKD09_RS01760	COG4191	Histidine kinase
BKD09_RS01760	COG0784	Response regulator, receiver
BKD09_RS01765	COG4566	intracellular signal transduction
BKD09_RS01775	COG2201	protein-glutamate methylesterase activity
BKD09_RS01795	COG0835	chemotaxis
BKD09_RS01800	COG0643	Histidine kinase
BKD09_RS01800	COG2198	Histidine kinase
BKD09_RS01800	COG0784	Response regulator, receiver
BKD09_RS01820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKD09_RS01850	COG0697	spore germination
BKD09_RS01855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKD09_RS01895	COG0583	DNA-binding transcription factor activity
BKD09_RS01900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKD09_RS01915	COG0473	3-isopropylmalate dehydrogenase activity
BKD09_RS01920	COG0066	3-isopropylmalate dehydratase activity
BKD09_RS01925	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BKD09_RS01930	COG0583	DNA-binding transcription factor activity
BKD09_RS01935	COG0653	protein targeting
BKD09_RS01970	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BKD09_RS01975	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BKD09_RS01995	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BKD09_RS02010	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BKD09_RS02015	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BKD09_RS02020	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BKD09_RS02025	COG0799	negative regulation of ribosome biogenesis
BKD09_RS02030	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BKD09_RS02040	COG0793	Belongs to the peptidase S41A family
BKD09_RS02050	COG1051	belongs to the nudix hydrolase family
BKD09_RS02055	COG0494	nUDIX hydrolase
BKD09_RS02065	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BKD09_RS02070	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BKD09_RS02075	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BKD09_RS02080	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BKD09_RS02085	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BKD09_RS02090	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BKD09_RS02100	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BKD09_RS02115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BKD09_RS02120	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS02130	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKD09_RS02140	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BKD09_RS02150	COG0045	succinate-CoA ligase (ADP-forming) activity
BKD09_RS02155	COG0039	L-malate dehydrogenase activity
BKD09_RS02160	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BKD09_RS02165	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BKD09_RS02170	COG2755	lipolytic protein G-D-S-L family
BKD09_RS02175	COG4181	ATPase activity
BKD09_RS02180	COG1136	(ABC) transporter
BKD09_RS02180	COG0577	efflux transmembrane transporter activity
BKD09_RS02185	COG0670	Belongs to the BI1 family
BKD09_RS02190	COG2801	Transposase and inactivated derivatives
BKD09_RS02190	COG3415	Transposase
BKD09_RS02210	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BKD09_RS02215	COG4133	protoheme IX ABC transporter activity
BKD09_RS02220	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BKD09_RS02225	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BKD09_RS02235	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKD09_RS02240	COG2917	probably involved in intracellular septation
BKD09_RS02245	COG0552	protein localization to endoplasmic reticulum
BKD09_RS02250	COG0564	pseudouridine synthase activity
BKD09_RS02260	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BKD09_RS02265	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BKD09_RS02285	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BKD09_RS02290	COG0228	four-way junction DNA binding
BKD09_RS02295	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BKD09_RS02300	COG0336	Belongs to the RNA methyltransferase TrmD family
BKD09_RS02305	COG0335	large ribosomal subunit rRNA binding
BKD09_RS02310	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BKD09_RS02355	COG0066	3-isopropylmalate dehydratase activity
BKD09_RS02380	COG2301	Belongs to the HpcH HpaI aldolase family
BKD09_RS02385	COG0288	reversible hydration of carbon dioxide
BKD09_RS02390	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BKD09_RS02410	COG0473	3-isopropylmalate dehydrogenase activity
BKD09_RS02420	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BKD09_RS02425	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
BKD09_RS02430	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BKD09_RS02440	COG0318	PFAM AMP-dependent synthetase and ligase
BKD09_RS02450	COG0730	response to heat
BKD09_RS02475	COG0784	Response regulator, receiver
BKD09_RS02475	COG4191	Histidine kinase
BKD09_RS02480	COG4178	(ABC) transporter
BKD09_RS02520	COG1785	Belongs to the alkaline phosphatase family
BKD09_RS02525	COG0137	argininosuccinate synthase activity
BKD09_RS02530	COG0671	phosphoesterase, PA-phosphatase related
BKD09_RS02540	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BKD09_RS02550	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS02555	COG0604	alcohol dehydrogenase
BKD09_RS02555	COG3321	synthase
BKD09_RS02555	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS02575	COG2154	pterin-4-alpha-carbinolamine dehydratase
BKD09_RS02590	COG0784	Response regulator, receiver
BKD09_RS02600	COG1217	gtp-binding protein TYPA
BKD09_RS02610	COG3011	Protein conserved in bacteria
BKD09_RS02630	COG1247	-acetyltransferase
BKD09_RS02635	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BKD09_RS02640	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BKD09_RS02660	COG1024	Enoyl-CoA hydratase
BKD09_RS02665	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BKD09_RS02670	COG4221	oxidoreductase activity
BKD09_RS02700	COG2814	Major facilitator Superfamily
BKD09_RS02760	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BKD09_RS02765	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BKD09_RS02775	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BKD09_RS02790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKD09_RS02795	COG1376	ErfK ybiS ycfS ynhG family protein
BKD09_RS02810	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BKD09_RS02810	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BKD09_RS02820	COG0138	bifunctional purine biosynthesis protein purh
BKD09_RS02830	COG0405	Gamma-glutamyltransferase
BKD09_RS02835	COG2814	Major facilitator Superfamily
BKD09_RS02850	COG0534	Mate efflux family protein
BKD09_RS02860	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BKD09_RS02875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKD09_RS02885	COG3118	belongs to the thioredoxin family
BKD09_RS02915	COG2835	tetraacyldisaccharide 4'-kinase activity
BKD09_RS02920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKD09_RS02925	COG1946	Acyl-CoA thioesterase
BKD09_RS02935	COG0347	Belongs to the P(II) protein family
BKD09_RS02940	COG0004	ammonium transporteR
BKD09_RS02945	COG0640	Transcriptional regulator
BKD09_RS02955	COG0740	serine-type endopeptidase activity
BKD09_RS02965	COG0347	Belongs to the P(II) protein family
BKD09_RS02970	COG0004	ammonium transporteR
BKD09_RS02985	COG0436	Aminotransferase
BKD09_RS02990	COG1674	ftsk spoiiie
BKD09_RS02995	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BKD09_RS03010	COG0745	RESPONSE REGULATOR receiver
BKD09_RS03025	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BKD09_RS03030	COG3706	GGDEF domain
BKD09_RS03030	COG2203	Gaf domain
BKD09_RS03030	COG5001	Diguanylate cyclase
BKD09_RS03030	COG4251	negative regulation of phosphorylation
BKD09_RS03035	COG3706	GGDEF domain
BKD09_RS03040	COG0495	leucyl-tRNA aminoacylation
BKD09_RS03065	COG0357	Ribosomal RNA small subunit methyltransferase G
BKD09_RS03070	COG0445	tRNA wobble uridine modification
BKD09_RS03075	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BKD09_RS03080	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BKD09_RS03085	COG1981	membrane
BKD09_RS03095	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BKD09_RS03100	COG0424	maF-like protein
BKD09_RS03105	COG0237	dephospho-CoA kinase activity
BKD09_RS03110	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BKD09_RS03115	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BKD09_RS03125	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BKD09_RS03140	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BKD09_RS03155	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BKD09_RS03160	COG0131	Imidazoleglycerol-phosphate dehydratase
BKD09_RS03170	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BKD09_RS03175	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BKD09_RS03180	COG0107	imidazoleglycerol-phosphate synthase activity
BKD09_RS03185	COG0140	phosphoribosyl-ATP diphosphatase activity
BKD09_RS03190	COG1072	(Pantothenic acid kinase))
BKD09_RS03195	COG0784	Response regulator, receiver
BKD09_RS03195	COG5002	protein histidine kinase activity
BKD09_RS03195	COG2205	protein histidine kinase activity
BKD09_RS03205	COG0606	chelatase, subunit chli
BKD09_RS03230	COG4964	Belongs to the GSP D family
BKD09_RS03240	COG0189	ligase activity
BKD09_RS03245	COG0792	nuclease activity
BKD09_RS03250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BKD09_RS03260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BKD09_RS03265	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BKD09_RS03270	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BKD09_RS03275	COG1420	regulation of RNA biosynthetic process
BKD09_RS03280	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BKD09_RS03285	COG1335	isochorismatase
BKD09_RS03295	COG0443	Heat shock 70 kDa protein
BKD09_RS03300	COG0484	heat shock protein binding
BKD09_RS03305	COG3963	phosphatidate phosphatase activity
BKD09_RS03310	COG0431	NADPH-dependent FMN reductase
BKD09_RS03315	COG0284	orotidine-5'-phosphate decarboxylase activity
BKD09_RS03335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKD09_RS03350	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BKD09_RS03355	COG0588	phosphoglycerate mutase activity
BKD09_RS03360	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BKD09_RS03370	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BKD09_RS03405	COG0864	Transcriptional regulator
BKD09_RS03415	COG1937	Protein conserved in bacteria
BKD09_RS03435	COG0072	phenylalanine-tRNA ligase activity
BKD09_RS03435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKD09_RS03440	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BKD09_RS03450	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BKD09_RS03455	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BKD09_RS03465	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BKD09_RS03490	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BKD09_RS03500	COG1968	undecaprenyl-diphosphatase activity
BKD09_RS03505	COG0277	FAD linked oxidase domain protein
BKD09_RS03510	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS03515	COG0702	epimerase
BKD09_RS03530	COG4774	siderophore transport
BKD09_RS03535	COG0243	molybdopterin cofactor binding
BKD09_RS03535	COG3383	formate dehydrogenase (NAD+) activity
BKD09_RS03540	COG0437	4 iron, 4 sulfur cluster binding
BKD09_RS03545	COG2864	formate dehydrogenase
BKD09_RS03575	COG5002	protein histidine kinase activity
BKD09_RS03580	COG0784	Response regulator, receiver
BKD09_RS03580	COG4191	Histidine kinase
BKD09_RS03585	COG2814	Major facilitator Superfamily
BKD09_RS03605	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BKD09_RS03610	COG1137	ATPase activity
BKD09_RS03615	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BKD09_RS03620	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BKD09_RS03625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKD09_RS03650	COG3268	Saccharopine dehydrogenase
BKD09_RS03655	COG0318	PFAM AMP-dependent synthetase and ligase
BKD09_RS03675	COG0071	Belongs to the small heat shock protein (HSP20) family
BKD09_RS03680	COG3842	ATPase activity
BKD09_RS03685	COG0395	ABC-type sugar transport system, permease component
BKD09_RS03705	COG1764	response to oxidative stress
BKD09_RS03710	COG1846	Transcriptional regulator
BKD09_RS03730	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BKD09_RS03735	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BKD09_RS03740	COG0539	negative regulation of cytoplasmic translation
BKD09_RS03745	COG0616	signal peptide processing
BKD09_RS03750	COG0776	regulation of translation
BKD09_RS03760	COG0135	phosphoribosylanthranilate isomerase activity
BKD09_RS03765	COG0133	tryptophan synthase activity
BKD09_RS03770	COG0159	tryptophan synthase activity
BKD09_RS03775	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BKD09_RS03800	COG1074	ATP-dependent DNA helicase activity
BKD09_RS03810	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BKD09_RS03820	COG3178	'Phosphotransferase
BKD09_RS03825	COG2205	protein histidine kinase activity
BKD09_RS03830	COG0756	dUTP diphosphatase activity
BKD09_RS03835	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BKD09_RS03840	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BKD09_RS03845	COG2226	methyltransferase
BKD09_RS03850	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BKD09_RS03870	COG3920	Histidine kinase
BKD09_RS03880	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BKD09_RS03885	COG0667	Aldo Keto reductase
BKD09_RS03910	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BKD09_RS03920	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BKD09_RS03925	COG0625	glutathione transferase activity
BKD09_RS03950	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BKD09_RS03955	COG1185	polyribonucleotide nucleotidyltransferase activity
BKD09_RS03960	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BKD09_RS03965	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BKD09_RS03970	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BKD09_RS03975	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BKD09_RS03990	COG0779	Required for maturation of 30S ribosomal subunits
BKD09_RS04000	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BKD09_RS04010	COG1396	sequence-specific DNA binding
BKD09_RS04015	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BKD09_RS04020	COG1253	flavin adenine dinucleotide binding
BKD09_RS04025	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BKD09_RS04030	COG1702	phosphate starvation-inducible protein PhoH
BKD09_RS04035	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BKD09_RS04040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKD09_RS04075	COG0180	Tryptophanyl-tRNA synthetase
BKD09_RS04085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKD09_RS04090	COG0318	PFAM AMP-dependent synthetase and ligase
BKD09_RS04130	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BKD09_RS04135	COG1741	Belongs to the pirin family
BKD09_RS04175	COG0534	Mate efflux family protein
BKD09_RS04180	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BKD09_RS04215	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BKD09_RS04225	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BKD09_RS04230	COG0268	Binds directly to 16S ribosomal RNA
BKD09_RS04240	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKD09_RS04255	COG0412	Dienelactone hydrolase
BKD09_RS04265	COG0596	Alpha beta hydrolase
BKD09_RS04325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKD09_RS04340	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BKD09_RS04400	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BKD09_RS04420	COG3706	GGDEF domain
BKD09_RS04425	COG5001	Diguanylate cyclase
BKD09_RS04455	COG3290	protein histidine kinase activity
BKD09_RS04455	COG3829	transcription factor binding
BKD09_RS04460	COG5001	Diguanylate cyclase
BKD09_RS04470	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS04490	COG0477	Major facilitator Superfamily
BKD09_RS04510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKD09_RS04515	COG0366	Alpha amylase catalytic
BKD09_RS04525	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BKD09_RS04535	COG1131	(ABC) transporter
BKD09_RS04560	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BKD09_RS04590	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BKD09_RS04600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKD09_RS04630	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BKD09_RS04635	COG0183	Belongs to the thiolase family
BKD09_RS04640	COG3485	protocatechuate 3,4-dioxygenase
BKD09_RS04645	COG3485	protocatechuate 3,4-dioxygenase
BKD09_RS04650	COG3485	protocatechuate 3,4-dioxygenase
BKD09_RS04680	COG0735	belongs to the Fur family
BKD09_RS04690	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BKD09_RS04695	COG2175	clavaminate synthase activity
BKD09_RS04700	COG0515	serine threonine protein kinase
BKD09_RS04700	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BKD09_RS04745	COG0142	geranyltranstransferase activity
BKD09_RS04750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKD09_RS04755	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BKD09_RS04770	COG3300	MHYT domain
BKD09_RS04770	COG5001	Diguanylate cyclase
BKD09_RS04790	COG5001	Diguanylate cyclase
BKD09_RS04800	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BKD09_RS04810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKD09_RS04815	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BKD09_RS04820	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BKD09_RS04825	COG1011	Hydrolase
BKD09_RS04835	COG2072	flavoprotein involved in K transport
BKD09_RS04840	COG0745	RESPONSE REGULATOR receiver
BKD09_RS04845	COG5002	protein histidine kinase activity
BKD09_RS04845	COG2198	Histidine kinase
BKD09_RS04845	COG0784	Response regulator, receiver
BKD09_RS04865	COG1129	ABC transporter
BKD09_RS04885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BKD09_RS04940	COG1960	acyl-CoA dehydrogenase activity
BKD09_RS04945	COG1960	acyl-CoA dehydrogenase activity
BKD09_RS04960	COG3246	L-lysine catabolic process to acetate
BKD09_RS04965	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BKD09_RS04980	COG4608	Belongs to the ABC transporter superfamily
BKD09_RS04985	COG0444	Belongs to the ABC transporter superfamily
BKD09_RS04990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKD09_RS04995	COG0601	transmembrane transport
BKD09_RS05010	COG1454	alcohol dehydrogenase
BKD09_RS05015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKD09_RS05025	COG0683	leucine binding
BKD09_RS05030	COG3788	relative of glutathione S-transferase, MAPEG superfamily
BKD09_RS05050	COG2271	Major facilitator Superfamily
BKD09_RS05060	COG2271	Major facilitator Superfamily
BKD09_RS05075	COG0737	Belongs to the 5'-nucleotidase family
BKD09_RS05110	COG1505	serine-type exopeptidase activity
BKD09_RS05115	COG2814	Major facilitator Superfamily
BKD09_RS05125	COG2514	catechol 2,3-dioxygenase activity
BKD09_RS05135	COG1960	acyl-CoA dehydrogenase activity
BKD09_RS05140	COG1960	acyl-CoA dehydrogenase activity
BKD09_RS05145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKD09_RS05175	COG1595	DNA-templated transcription, initiation
BKD09_RS05185	COG3437	response regulator, receiver
BKD09_RS05185	COG0784	Response regulator, receiver
BKD09_RS05190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKD09_RS05190	COG4191	Histidine kinase
BKD09_RS05195	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BKD09_RS05210	COG0747	negative chemotaxis
BKD09_RS05215	COG0601	transmembrane transport
BKD09_RS05220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKD09_RS05225	COG4172	Belongs to the ABC transporter superfamily
BKD09_RS05245	COG1802	Transcriptional regulator
BKD09_RS05270	COG2124	cytochrome p450
BKD09_RS05285	COG1252	NADH dehydrogenase
BKD09_RS05295	COG1082	Xylose isomerase domain protein TIM barrel
BKD09_RS05295	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BKD09_RS05315	COG0559	Belongs to the binding-protein-dependent transport system permease family
BKD09_RS05325	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BKD09_RS05330	COG0583	DNA-binding transcription factor activity
BKD09_RS05340	COG2197	response regulator
BKD09_RS05345	COG3916	Acyl-homoserine-lactone synthase
BKD09_RS05380	COG4774	siderophore transport
BKD09_RS05390	COG4638	Rieske (2fe-2S)
BKD09_RS05395	COG1414	Transcriptional regulator
BKD09_RS05405	COG4651	solute:proton antiporter activity
BKD09_RS05405	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BKD09_RS05415	COG2346	COG2346, Truncated hemoglobins
BKD09_RS05420	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BKD09_RS05475	COG0596	Alpha beta hydrolase
BKD09_RS05490	COG5002	protein histidine kinase activity
BKD09_RS05495	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BKD09_RS05500	COG0573	inorganic phosphate transmembrane transporter activity
BKD09_RS05505	COG0581	inorganic phosphate transmembrane transporter activity
BKD09_RS05510	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BKD09_RS05515	COG0704	Plays a role in the regulation of phosphate uptake
BKD09_RS05520	COG0745	RESPONSE REGULATOR receiver
BKD09_RS05530	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BKD09_RS05535	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BKD09_RS05545	COG2967	ApaG domain
BKD09_RS05570	COG0717	Belongs to the dCTP deaminase family
BKD09_RS05575	COG4191	Histidine kinase
BKD09_RS05610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BKD09_RS05625	COG1396	sequence-specific DNA binding
BKD09_RS05645	COG1070	Carbohydrate kinase
BKD09_RS05650	COG2115	Belongs to the xylose isomerase family
BKD09_RS05655	COG1129	ABC transporter
BKD09_RS05660	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKD09_RS05685	COG0251	oxidation-reduction process
BKD09_RS05710	COG1999	signal sequence binding
BKD09_RS05725	COG3338	carbonate dehydratase activity
BKD09_RS05740	COG0167	dihydroorotate dehydrogenase activity
BKD09_RS05750	COG1234	tRNA 3'-trailer cleavage
BKD09_RS05780	COG1201	RNA secondary structure unwinding
BKD09_RS05800	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BKD09_RS05805	COG0625	glutathione transferase activity
BKD09_RS05810	COG1280	lysine exporter protein (LysE YggA)
BKD09_RS05815	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BKD09_RS05815	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BKD09_RS05825	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BKD09_RS05830	COG1643	Atp-dependent helicase
BKD09_RS05835	COG3577	Aspartyl protease
BKD09_RS05840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BKD09_RS05845	COG1522	sequence-specific DNA binding
BKD09_RS05850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKD09_RS05855	COG2816	NAD+ diphosphatase activity
BKD09_RS05875	COG1126	abc transporter atp-binding protein
BKD09_RS05880	COG0765	amino acid transport
BKD09_RS05885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKD09_RS05890	COG0753	catalase activity
BKD09_RS05900	COG4977	sequence-specific DNA binding
BKD09_RS05910	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BKD09_RS05915	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BKD09_RS05920	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BKD09_RS05930	COG2223	nitrite transmembrane transporter activity
BKD09_RS05940	COG0242	peptide deformylase activity
BKD09_RS05945	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BKD09_RS05950	COG0101	tRNA pseudouridine synthase activity
BKD09_RS05955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKD09_RS05965	COG2171	N-acyltransferase activity
BKD09_RS05980	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BKD09_RS05990	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BKD09_RS05995	COG0706	membrane insertase activity
BKD09_RS06000	COG0594	ribonuclease P activity
BKD09_RS06010	COG3852	Histidine kinase
BKD09_RS06045	COG2902	Dehydrogenase
BKD09_RS06065	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BKD09_RS06075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKD09_RS06080	COG0583	DNA-binding transcription factor activity
BKD09_RS06095	COG2207	Transcriptional regulator
BKD09_RS06120	COG1959	2 iron, 2 sulfur cluster binding
BKD09_RS06125	COG1032	radical SAM domain protein
BKD09_RS06135	COG1802	Transcriptional regulator
BKD09_RS06140	COG0277	FAD linked oxidase domain protein
BKD09_RS06145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKD09_RS06150	COG4774	siderophore transport
BKD09_RS06155	COG1840	ABC-type Fe3 transport system, periplasmic component
BKD09_RS06170	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKD09_RS06180	COG2610	gluconate transmembrane transporter activity
BKD09_RS06185	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BKD09_RS06200	COG1309	transcriptional regulator
BKD09_RS06210	COG1024	Enoyl-CoA hydratase
BKD09_RS06235	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BKD09_RS06240	COG3454	Phosphonate metabolism
BKD09_RS06250	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BKD09_RS06265	COG3639	organic phosphonate transmembrane transporter activity
BKD09_RS06270	COG2188	Transcriptional regulator
BKD09_RS06275	COG3624	Phosphonate C-P lyase system protein PhnG
BKD09_RS06280	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
BKD09_RS06285	COG3626	phosphonate metabolism
BKD09_RS06290	COG3627	carbon phosphorus lyase activity
BKD09_RS06295	COG4107	phosphonate C-P lyase system protein PhnK
BKD09_RS06300	COG4778	phosphonate C-P lyase system protein PhnL
BKD09_RS06305	COG3454	Phosphonate metabolism
BKD09_RS06310	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BKD09_RS06320	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS06330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKD09_RS06335	COG2267	carboxylic ester hydrolase activity
BKD09_RS06350	COG3181	Tripartite tricarboxylate transporter family receptor
BKD09_RS06355	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BKD09_RS06360	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKD09_RS06365	COG3971	2-oxopent-4-enoate hydratase activity
BKD09_RS06380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKD09_RS06415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKD09_RS06440	COG0492	ferredoxin-NADP+ reductase activity
BKD09_RS06460	COG1309	transcriptional regulator
BKD09_RS06470	COG0702	epimerase
BKD09_RS06480	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BKD09_RS06485	COG5328	Belongs to the UPF0262 family
BKD09_RS06490	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BKD09_RS06495	COG0424	maF-like protein
BKD09_RS06500	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BKD09_RS06530	COG4191	Histidine kinase
BKD09_RS06530	COG0784	Response regulator, receiver
BKD09_RS06555	COG1335	isochorismatase
BKD09_RS06575	COG0667	Aldo Keto reductase
BKD09_RS06605	COG2358	TRAP transporter, solute receptor (TAXI family
BKD09_RS06620	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS06655	COG3047	cAMP biosynthetic process
BKD09_RS06665	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BKD09_RS06670	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BKD09_RS06675	COG0328	RNA-DNA hybrid ribonuclease activity
BKD09_RS06680	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BKD09_RS06680	COG0678	peroxiredoxin activity
BKD09_RS06690	COG0318	PFAM AMP-dependent synthetase and ligase
BKD09_RS06695	COG1686	Belongs to the peptidase S11 family
BKD09_RS06700	COG1132	(ABC) transporter
BKD09_RS06715	COG0140	phosphoribosyl-ATP diphosphatase activity
BKD09_RS06720	COG1238	metal cluster binding
BKD09_RS06730	COG1027	Aspartate ammonia-lyase
BKD09_RS06745	COG0318	PFAM AMP-dependent synthetase and ligase
BKD09_RS06750	COG2070	2-Nitropropane dioxygenase
BKD09_RS06795	COG4585	Histidine kinase
BKD09_RS06845	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BKD09_RS06880	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BKD09_RS06880	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BKD09_RS06895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKD09_RS06900	COG1473	amidohydrolase
BKD09_RS06910	COG0601	transmembrane transport
BKD09_RS06915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKD09_RS06920	COG0444	Belongs to the ABC transporter superfamily
BKD09_RS06925	COG4608	Belongs to the ABC transporter superfamily
BKD09_RS06940	COG5001	Diguanylate cyclase
BKD09_RS06940	COG4251	negative regulation of phosphorylation
BKD09_RS06940	COG2203	Gaf domain
BKD09_RS06940	COG3706	GGDEF domain
BKD09_RS06945	COG3360	Dodecin
BKD09_RS06960	COG2273	Hydrolase Family 16
BKD09_RS06960	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
BKD09_RS06965	COG2723	6-phospho-beta-galactosidase activity
BKD09_RS06985	COG0446	pyridine nucleotide-disulphide oxidoreductase
BKD09_RS06995	COG0318	PFAM AMP-dependent synthetase and ligase
BKD09_RS07010	COG0583	DNA-binding transcription factor activity
BKD09_RS07020	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BKD09_RS07045	COG2086	electron transfer activity
BKD09_RS07050	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BKD09_RS07055	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKD09_RS07065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKD09_RS07070	COG0165	Argininosuccinate lyase
BKD09_RS07080	COG0019	diaminopimelate decarboxylase activity
BKD09_RS07090	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKD09_RS07105	COG2204	response regulator
BKD09_RS07115	COG2884	Cell division ATP-binding protein ftsE
BKD09_RS07145	COG0287	Prephenate dehydrogenase
BKD09_RS07150	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BKD09_RS07160	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BKD09_RS07165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BKD09_RS07165	COG2813	Specifically methylates the guanine in position
BKD09_RS07185	COG0542	response to heat
BKD09_RS07200	COG0739	heme binding
BKD09_RS07240	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BKD09_RS07245	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BKD09_RS07265	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BKD09_RS07270	COG5285	phytanoyl-CoA dioxygenase
BKD09_RS07285	COG1595	DNA-templated transcription, initiation
BKD09_RS07290	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKD09_RS07300	COG2267	carboxylic ester hydrolase activity
BKD09_RS07310	COG0318	PFAM AMP-dependent synthetase and ligase
BKD09_RS07340	COG1960	acyl-CoA dehydrogenase activity
BKD09_RS07345	COG1960	acyl-CoA dehydrogenase activity
BKD09_RS07350	COG1960	acyl-CoA dehydrogenase activity
BKD09_RS07355	COG0778	Nitroreductase
BKD09_RS07370	COG0784	Response regulator, receiver
BKD09_RS07425	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BKD09_RS07470	COG0326	Molecular chaperone. Has ATPase activity
BKD09_RS07490	COG0318	PFAM AMP-dependent synthetase and ligase
BKD09_RS07505	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS07540	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BKD09_RS07560	COG1121	(ABC) transporter
BKD09_RS07570	COG0803	Belongs to the bacterial solute-binding protein 9 family
BKD09_RS07575	COG0523	cobalamin synthesis protein
BKD09_RS07595	COG4689	acetoacetate decarboxylase
BKD09_RS07635	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BKD09_RS07650	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BKD09_RS07665	COG0330	HflC and HflK could
BKD09_RS07705	COG0069	glutamate synthase activity
BKD09_RS07705	COG0067	glutamate synthase
BKD09_RS07705	COG0070	glutamate synthase
BKD09_RS07720	COG0071	Belongs to the small heat shock protein (HSP20) family
BKD09_RS07730	COG2010	Cytochrome c
BKD09_RS07740	COG1280	lysine exporter protein (LysE YggA)
BKD09_RS07755	COG0583	DNA-binding transcription factor activity
BKD09_RS07765	COG0483	inositol monophosphate 1-phosphatase activity
BKD09_RS07860	COG1231	oxidoreductase activity
BKD09_RS07870	COG2205	protein histidine kinase activity
BKD09_RS07885	COG1472	Belongs to the glycosyl hydrolase 3 family
BKD09_RS07890	COG0747	negative chemotaxis
BKD09_RS07935	COG2146	nitrite reductase [NAD(P)H] activity
BKD09_RS07950	COG1012	belongs to the aldehyde dehydrogenase family
BKD09_RS07955	COG1902	pentaerythritol trinitrate reductase activity
BKD09_RS07990	COG0765	amino acid transport
BKD09_RS07995	COG0765	amino acid transport
BKD09_RS08000	COG1126	abc transporter atp-binding protein
BKD09_RS08010	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKD09_RS08025	COG0583	DNA-binding transcription factor activity
BKD09_RS08045	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKD09_RS08055	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BKD09_RS08070	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BKD09_RS08075	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BKD09_RS08095	COG1215	transferase activity, transferring glycosyl groups
BKD09_RS08120	COG1522	sequence-specific DNA binding
BKD09_RS08125	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BKD09_RS08130	COG0655	NAD(P)H dehydrogenase (quinone) activity
BKD09_RS08135	COG1741	Belongs to the pirin family
BKD09_RS08145	COG0583	DNA-binding transcription factor activity
BKD09_RS08150	COG1943	Transposase
BKD09_RS08175	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BKD09_RS08205	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BKD09_RS08230	COG3474	cytochrome
BKD09_RS08235	COG0277	FAD linked oxidase domain protein
BKD09_RS08250	COG0277	FAD linked oxidase domain protein
BKD09_RS08255	COG0247	lactate metabolic process
BKD09_RS08270	COG4178	(ABC) transporter
BKD09_RS08275	COG1620	l-lactate permease
BKD09_RS08290	COG0459	protein refolding
BKD09_RS08295	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BKD09_RS08310	COG1388	LysM domain
BKD09_RS08310	COG1376	ErfK ybiS ycfS ynhG family protein
BKD09_RS08315	COG3416	Protein conserved in bacteria
BKD09_RS08325	COG0463	Glycosyl transferase, family 2
BKD09_RS08330	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BKD09_RS08335	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BKD09_RS08375	COG0312	modulator of DNA gyrase
BKD09_RS08395	COG1519	Transferase
BKD09_RS08400	COG1663	tetraacyldisaccharide 4'-kinase activity
BKD09_RS08430	COG1570	exodeoxyribonuclease VII activity
BKD09_RS08450	COG0151	Belongs to the GarS family
BKD09_RS08455	COG0596	Alpha beta hydrolase
BKD09_RS08460	COG0590	tRNA wobble adenosine to inosine editing
BKD09_RS08465	COG1187	pseudouridine synthase activity
BKD09_RS08470	COG0742	ribosomal rna small subunit methyltransferase
BKD09_RS08475	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BKD09_RS08515	COG0612	Peptidase, M16
BKD09_RS08520	COG0612	Peptidase, M16
BKD09_RS08530	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BKD09_RS08535	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BKD09_RS08540	COG0196	riboflavin kinase activity
BKD09_RS08545	COG0745	RESPONSE REGULATOR receiver
BKD09_RS08555	COG2200	EAL domain
BKD09_RS08555	COG2771	luxR family
BKD09_RS08570	COG1295	ribonuclease BN
BKD09_RS08580	COG2890	protein-(glutamine-N5) methyltransferase activity
BKD09_RS08585	COG0314	molybdopterin synthase activity
BKD09_RS08595	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BKD09_RS08600	COG0322	excinuclease ABC activity
BKD09_RS08605	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BKD09_RS08610	COG1278	Cold shock
BKD09_RS08615	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BKD09_RS08650	COG0745	RESPONSE REGULATOR receiver
BKD09_RS08655	COG1846	Transcriptional regulator
BKD09_RS08670	COG0124	histidyl-tRNA synthetase
BKD09_RS08675	COG1942	4-Oxalocrotonate Tautomerase
BKD09_RS08685	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BKD09_RS08695	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BKD09_RS08720	COG0542	response to heat
BKD09_RS08730	COG3608	succinylglutamate desuccinylase aspartoacylase
BKD09_RS08730	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BKD09_RS08740	COG1181	Belongs to the D-alanine--D-alanine ligase family
BKD09_RS08750	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BKD09_RS08765	COG1496	oxidoreductase activity
BKD09_RS08775	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BKD09_RS08790	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BKD09_RS08795	COG0193	aminoacyl-tRNA hydrolase activity
BKD09_RS08800	COG0012	GTP binding
BKD09_RS08810	COG2030	dehydratase
BKD09_RS08855	COG0556	nucleotide-excision repair
BKD09_RS08870	COG0583	DNA-binding transcription factor activity
BKD09_RS08910	COG0667	Aldo Keto reductase
BKD09_RS08930	COG0625	glutathione transferase activity
BKD09_RS08935	COG0436	Aminotransferase
BKD09_RS08945	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BKD09_RS08955	COG0659	secondary active sulfate transmembrane transporter activity
BKD09_RS08965	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BKD09_RS08980	COG1304	FMN binding
BKD09_RS08990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BKD09_RS08995	COG2223	nitrite transmembrane transporter activity
BKD09_RS09010	COG0625	glutathione transferase activity
BKD09_RS09030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKD09_RS09035	COG0183	Belongs to the thiolase family
BKD09_RS09040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKD09_RS09045	COG2205	protein histidine kinase activity
BKD09_RS09095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKD09_RS09100	COG0583	DNA-binding transcription factor activity
BKD09_RS09105	COG0492	ferredoxin-NADP+ reductase activity
BKD09_RS09110	COG1522	sequence-specific DNA binding
BKD09_RS09115	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BKD09_RS09120	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BKD09_RS09125	COG2814	Major facilitator Superfamily
BKD09_RS09150	COG0505	Belongs to the CarA family
BKD09_RS09165	COG0596	Alpha beta hydrolase
BKD09_RS09170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKD09_RS09175	COG1846	Transcriptional regulator
BKD09_RS09230	COG0640	Transcriptional regulator
BKD09_RS09245	COG1280	lysine exporter protein (LysE YggA)
BKD09_RS09275	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BKD09_RS09305	COG1280	lysine exporter protein (LysE YggA)
BKD09_RS09330	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BKD09_RS09335	COG0564	pseudouridine synthase activity
BKD09_RS09365	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BKD09_RS09405	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BKD09_RS09410	COG3284	Transcriptional regulator
BKD09_RS09425	COG3734	2-keto-3-deoxy-galactonokinase
BKD09_RS09430	COG0800	Aldolase
BKD09_RS09435	COG0028	Belongs to the TPP enzyme family
BKD09_RS09480	COG2205	protein histidine kinase activity
BKD09_RS09490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKD09_RS09495	COG2514	catechol 2,3-dioxygenase activity
BKD09_RS09500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKD09_RS09510	COG1960	acyl-CoA dehydrogenase activity
BKD09_RS09515	COG1960	acyl-CoA dehydrogenase activity
BKD09_RS09520	COG1024	Enoyl-CoA hydratase
BKD09_RS09525	COG1704	LemA family
BKD09_RS09530	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BKD09_RS09550	COG0625	glutathione transferase activity
BKD09_RS09570	COG1278	Cold shock
BKD09_RS09610	COG3768	UPF0283 membrane protein
BKD09_RS09615	COG3106	COG3106 Predicted ATPase
BKD09_RS09620	COG1272	protein, Hemolysin III
BKD09_RS09625	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS09635	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS09645	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
BKD09_RS09655	COG1960	acyl-CoA dehydrogenase activity
BKD09_RS09660	COG0583	DNA-binding transcription factor activity
BKD09_RS09680	COG0501	Belongs to the peptidase M48B family
BKD09_RS09685	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BKD09_RS09700	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BKD09_RS09710	COG1388	LysM domain
BKD09_RS09710	COG1376	ErfK ybiS ycfS ynhG family protein
BKD09_RS09715	COG0028	Belongs to the TPP enzyme family
BKD09_RS09745	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BKD09_RS09805	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS09830	COG0824	Thioesterase
BKD09_RS09835	COG0824	Thioesterase
BKD09_RS09845	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BKD09_RS09845	COG0519	Catalyzes the synthesis of GMP from XMP
BKD09_RS09865	COG0765	amino acid transport
BKD09_RS09870	COG1126	abc transporter atp-binding protein
BKD09_RS09875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKD09_RS09895	COG0402	S-adenosylhomocysteine deaminase activity
BKD09_RS09910	COG3842	ATPase activity
BKD09_RS09915	COG1176	ABC-type spermidine putrescine transport system, permease component I
BKD09_RS09920	COG1177	transmembrane transport
BKD09_RS09965	COG0488	(ABC) transporter
BKD09_RS09970	COG1301	dicarboxylic acid transport
BKD09_RS09975	COG2233	PERMEase
BKD09_RS09980	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS10005	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BKD09_RS10040	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BKD09_RS10045	COG0625	glutathione transferase activity
BKD09_RS10050	COG1309	transcriptional regulator
BKD09_RS10055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKD09_RS10060	COG3795	YCII-related domain
BKD09_RS10065	COG4941	Belongs to the sigma-70 factor family
BKD09_RS10095	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS10115	COG3795	YCII-related domain
BKD09_RS10145	COG1045	serine acetyltransferase
BKD09_RS10175	COG0823	Involved in the tonB-independent uptake of proteins
BKD09_RS10180	COG5001	Diguanylate cyclase
BKD09_RS10190	COG2885	chlorophyll binding
BKD09_RS10200	COG0037	tRNA processing
BKD09_RS10205	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKD09_RS10220	COG1309	transcriptional regulator
BKD09_RS10265	COG0469	pyruvate kinase activity
BKD09_RS10280	COG3750	Belongs to the UPF0335 family
BKD09_RS10295	COG3108	Peptidase M15
BKD09_RS10300	COG2989	Protein conserved in bacteria
BKD09_RS10305	COG2204	response regulator
BKD09_RS10340	COG1073	alpha beta
BKD09_RS10345	COG0387	Pfam Sodium calcium exchanger
BKD09_RS10365	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BKD09_RS10370	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BKD09_RS10375	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BKD09_RS10380	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BKD09_RS10385	COG5002	protein histidine kinase activity
BKD09_RS10385	COG3447	MASE1 domain protein
BKD09_RS10385	COG5001	Diguanylate cyclase
BKD09_RS10410	COG0579	oxidoreductase
BKD09_RS10415	COG3300	MHYT domain
BKD09_RS10415	COG5001	Diguanylate cyclase
BKD09_RS10425	COG3842	ATPase activity
BKD09_RS10430	COG1176	ABC-type spermidine putrescine transport system, permease component I
BKD09_RS10435	COG1177	transmembrane transport
BKD09_RS10455	COG1175	transmembrane transport
BKD09_RS10505	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BKD09_RS10530	COG4566	intracellular signal transduction
BKD09_RS10540	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BKD09_RS10545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKD09_RS10560	COG4771	TonB-dependent receptor
BKD09_RS10580	COG0848	biopolymer transport protein
BKD09_RS10600	COG0395	ABC-type sugar transport system, permease component
BKD09_RS10605	COG1175	transmembrane transport
BKD09_RS10615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKD09_RS10620	COG0840	transmembrane signaling receptor activity
BKD09_RS10630	COG0697	spore germination
BKD09_RS10645	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BKD09_RS10690	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKD09_RS10695	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKD09_RS10705	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BKD09_RS10710	COG3005	denitrification pathway
BKD09_RS10715	COG3043	anaerobic respiration
BKD09_RS10720	COG0243	molybdopterin cofactor binding
BKD09_RS10745	COG0490	domain, Protein
BKD09_RS10745	COG0471	metal ion transport
BKD09_RS10760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKD09_RS10780	COG1376	ErfK ybiS ycfS ynhG family protein
BKD09_RS10790	COG2124	cytochrome p450
BKD09_RS10800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKD09_RS10805	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKD09_RS10810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKD09_RS10815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKD09_RS10820	COG1116	anion transmembrane transporter activity
BKD09_RS10825	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BKD09_RS10840	COG2204	response regulator
BKD09_RS10845	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BKD09_RS10855	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BKD09_RS10860	COG1766	The M ring may be actively involved in energy transduction
BKD09_RS10870	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BKD09_RS10880	COG0482	sulfurtransferase activity
BKD09_RS10915	COG2226	methyltransferase
BKD09_RS10950	COG1793	dna ligase
BKD09_RS10975	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BKD09_RS10975	COG1672	PFAM Archaeal ATPase
BKD09_RS11005	COG0583	DNA-binding transcription factor activity
BKD09_RS11015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKD09_RS11055	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS11065	COG3243	poly(R)-hydroxyalkanoic acid synthase
BKD09_RS11085	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BKD09_RS11110	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BKD09_RS11140	COG0596	Alpha beta hydrolase
BKD09_RS11155	COG2814	Major facilitator Superfamily
BKD09_RS11165	COG3258	Cytochrome c
BKD09_RS11220	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
BKD09_RS11235	COG2197	response regulator
BKD09_RS11275	COG4191	Histidine kinase
BKD09_RS11275	COG0784	Response regulator, receiver
BKD09_RS11290	COG1175	transmembrane transport
BKD09_RS11295	COG0395	ABC-type sugar transport system, permease component
BKD09_RS11305	COG3842	ATPase activity
BKD09_RS11310	COG3842	ATPase activity
BKD09_RS11315	COG1461	Dihydroxyacetone kinase
BKD09_RS11325	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKD09_RS11340	COG2376	Dihydroxyacetone kinase
BKD09_RS11385	COG0235	Class ii aldolase
BKD09_RS11395	COG4211	Belongs to the binding-protein-dependent transport system permease family
BKD09_RS11400	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKD09_RS11405	COG1129	ABC transporter
BKD09_RS11425	COG3284	Transcriptional regulator
BKD09_RS11430	COG1063	alcohol dehydrogenase
BKD09_RS11475	COG0459	protein refolding
BKD09_RS11480	COG3284	Transcriptional regulator
BKD09_RS11500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKD09_RS11515	COG3258	Cytochrome c
BKD09_RS11545	COG1309	transcriptional regulator
BKD09_RS11550	COG0534	Mate efflux family protein
BKD09_RS11560	COG1464	Belongs to the NlpA lipoprotein family
BKD09_RS11565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKD09_RS11580	COG0683	leucine binding
BKD09_RS11590	COG0411	ABC transporter
BKD09_RS11600	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BKD09_RS11625	COG1846	Transcriptional regulator
BKD09_RS11630	COG1157	protein secretion by the type III secretion system
BKD09_RS11635	COG4786	Flagellar basal body rod
BKD09_RS11645	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BKD09_RS11660	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BKD09_RS11665	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BKD09_RS11670	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BKD09_RS11675	COG1815	bacterial-type flagellum-dependent cell motility
BKD09_RS11680	COG1558	bacterial-type flagellum-dependent cell motility
BKD09_RS11685	COG1677	Flagellar hook-basal body complex protein FliE
BKD09_RS11690	COG4786	Flagellar basal body rod
BKD09_RS11700	COG1706	bacterial-type flagellum-dependent cell motility
BKD09_RS11710	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BKD09_RS11720	COG1338	Plays a role in the flagellum-specific transport system
BKD09_RS11725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BKD09_RS11730	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BKD09_RS11735	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BKD09_RS11750	COG1360	Flagellar Motor Protein
BKD09_RS11770	COG1749	Flagellar hook protein flgE
BKD09_RS11790	COG5443	negative regulation of bacterial-type flagellum assembly
BKD09_RS11795	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BKD09_RS11805	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BKD09_RS11810	COG1684	flagellar biosynthetic protein fliR
BKD09_RS11855	COG0412	Dienelactone hydrolase
BKD09_RS11880	COG0246	Mannitol dehydrogenase
BKD09_RS11885	COG2186	Transcriptional regulator
BKD09_RS11890	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BKD09_RS11900	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BKD09_RS11905	COG1063	alcohol dehydrogenase
BKD09_RS11920	COG0583	DNA-binding transcription factor activity
BKD09_RS11925	COG3842	ATPase activity
BKD09_RS11935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKD09_RS11945	COG1176	ABC-type spermidine putrescine transport system, permease component I
BKD09_RS11950	COG4208	sulfate ABC transporter
BKD09_RS11955	COG1309	transcriptional regulator
BKD09_RS11960	COG0477	Major facilitator Superfamily
BKD09_RS11965	COG2272	Belongs to the type-B carboxylesterase lipase family
BKD09_RS11995	COG0765	amino acid transport
BKD09_RS12005	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKD09_RS12010	COG0251	oxidation-reduction process
BKD09_RS12015	COG0436	Aminotransferase
BKD09_RS12020	COG0028	Belongs to the TPP enzyme family
BKD09_RS12025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKD09_RS12055	COG0395	ABC-type sugar transport system, permease component
BKD09_RS12060	COG1175	transmembrane transport
BKD09_RS12070	COG1609	Transcriptional regulator
BKD09_RS12080	COG1414	Transcriptional regulator
BKD09_RS12085	COG1053	succinate dehydrogenase
BKD09_RS12095	COG0477	Major facilitator Superfamily
BKD09_RS12105	COG0583	DNA-binding transcription factor activity
BKD09_RS12140	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BKD09_RS12170	COG2030	dehydratase
BKD09_RS12200	COG0427	acetyl-CoA hydrolase
BKD09_RS12210	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BKD09_RS12230	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKD09_RS12260	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BKD09_RS12265	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BKD09_RS12270	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BKD09_RS12275	COG2205	protein histidine kinase activity
BKD09_RS12285	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BKD09_RS12310	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BKD09_RS12320	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BKD09_RS12330	COG0366	Alpha amylase catalytic
BKD09_RS12335	COG1640	4-alpha-glucanotransferase
BKD09_RS12340	COG3387	PFAM Glycoside hydrolase 15-related
BKD09_RS12350	COG3265	gluconokinase activity
BKD09_RS12355	COG0363	glucosamine-6-phosphate deaminase activity
BKD09_RS12360	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BKD09_RS12365	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BKD09_RS12370	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BKD09_RS12380	COG2766	serine protein kinase
BKD09_RS12385	COG2718	Belongs to the UPF0229 family
BKD09_RS12390	COG2719	SpoVR family
BKD09_RS12440	COG1013	pyruvate-flavodoxin oxidoreductase activity
BKD09_RS12445	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BKD09_RS12445	COG0674	pyruvate-flavodoxin oxidoreductase activity
BKD09_RS12465	COG0535	radical SAM domain protein
BKD09_RS12470	COG0535	radical SAM domain protein
BKD09_RS12475	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
BKD09_RS12480	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BKD09_RS12495	COG0154	amidase activity
BKD09_RS12500	COG0386	Belongs to the glutathione peroxidase family
BKD09_RS12510	COG4948	Mandelate Racemase Muconate Lactonizing
BKD09_RS12515	COG2311	Membrane
BKD09_RS12580	COG2072	flavoprotein involved in K transport
BKD09_RS12605	COG0747	negative chemotaxis
BKD09_RS12610	COG0601	transmembrane transport
BKD09_RS12615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKD09_RS12625	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKD09_RS12635	COG2207	Transcriptional regulator
BKD09_RS12645	COG1672	PFAM Archaeal ATPase
BKD09_RS12645	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BKD09_RS12670	COG4948	Mandelate Racemase Muconate Lactonizing
BKD09_RS12675	COG2207	Transcriptional regulator
BKD09_RS12675	COG3708	Transcriptional regulator
BKD09_RS12690	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BKD09_RS12700	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKD09_RS12715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BKD09_RS12720	COG2897	thiosulfate sulfurtransferase activity
BKD09_RS12730	COG1376	ErfK ybiS ycfS ynhG family protein
BKD09_RS12735	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKD09_RS12775	COG2193	ferroxidase activity
BKD09_RS12805	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BKD09_RS12825	COG2204	response regulator
BKD09_RS12830	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS12870	COG0625	glutathione transferase activity
BKD09_RS12895	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BKD09_RS12905	COG2022	thiamine diphosphate biosynthetic process
BKD09_RS12960	COG1176	ABC-type spermidine putrescine transport system, permease component I
BKD09_RS12970	COG3842	ATPase activity
BKD09_RS13020	COG1376	ErfK ybiS ycfS ynhG family protein
BKD09_RS13020	COG1388	LysM domain
BKD09_RS13045	COG0688	phosphatidylethanolamine metabolic process
BKD09_RS13095	COG1309	transcriptional regulator
BKD09_RS13110	COG5265	(ABC) transporter
BKD09_RS13135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKD09_RS13155	COG3795	YCII-related domain
BKD09_RS13160	COG3795	YCII-related domain
BKD09_RS13165	COG4941	Belongs to the sigma-70 factor family
BKD09_RS13170	COG3023	N-Acetylmuramoyl-L-alanine amidase
BKD09_RS13175	COG0275	rRNA processing
BKD09_RS13190	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BKD09_RS13195	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BKD09_RS13200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BKD09_RS13205	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BKD09_RS13220	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BKD09_RS13225	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BKD09_RS13230	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BKD09_RS13235	COG1181	Belongs to the D-alanine--D-alanine ligase family
BKD09_RS13240	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BKD09_RS13245	COG0849	cell division
BKD09_RS13250	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BKD09_RS13260	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BKD09_RS13270	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BKD09_RS13275	COG2814	Major facilitator Superfamily
BKD09_RS13280	COG0006	proline dipeptidase activity
BKD09_RS13280	COG0006	proline dipeptidase activity
BKD09_RS13290	COG2264	protein methyltransferase activity
BKD09_RS13315	COG0584	glycerophosphoryl diester phosphodiesterase
BKD09_RS13335	COG0842	Transport permease protein
BKD09_RS13340	COG1131	(ABC) transporter
BKD09_RS13350	COG2124	cytochrome p450
BKD09_RS13405	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
BKD09_RS13465	COG0210	DNA helicase
BKD09_RS13470	COG5487	UPF0391 membrane protein
BKD09_RS13480	COG0277	FAD linked oxidase domain protein
BKD09_RS13495	COG3842	ATPase activity
BKD09_RS13500	COG0395	ABC-type sugar transport system, permease component
BKD09_RS13505	COG1175	transmembrane transport
BKD09_RS13525	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BKD09_RS13530	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BKD09_RS13535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKD09_RS13545	COG5001	Diguanylate cyclase
BKD09_RS13545	COG3300	MHYT domain
BKD09_RS13550	COG2271	Major facilitator Superfamily
BKD09_RS13555	COG2199	diguanylate cyclase activity
BKD09_RS13555	COG2202	Pas domain
BKD09_RS13555	COG2200	EAL domain
BKD09_RS13565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKD09_RS13610	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS13615	COG1309	transcriptional regulator
BKD09_RS13620	COG0589	response to stress
BKD09_RS13630	COG0519	Catalyzes the synthesis of GMP from XMP
BKD09_RS13640	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
BKD09_RS13675	COG0114	fumarate hydratase activity
BKD09_RS13715	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BKD09_RS13730	COG0330	HflC and HflK could
BKD09_RS13735	COG0330	HflC and HflK could
BKD09_RS13750	COG0560	Phosphoserine phosphatase
BKD09_RS13755	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BKD09_RS13760	COG0028	Belongs to the TPP enzyme family
BKD09_RS13770	COG0440	acetolactate synthase activity
BKD09_RS13790	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BKD09_RS13795	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS13815	COG1174	glycine betaine transport
BKD09_RS13820	COG1125	glycine betaine transport
BKD09_RS13820	COG0517	IMP dehydrogenase activity
BKD09_RS13830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKD09_RS13895	COG2326	polyphosphate kinase activity
BKD09_RS13920	COG0668	transmembrane transport
BKD09_RS13930	COG0281	malic enzyme
BKD09_RS13965	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BKD09_RS13980	COG2072	flavoprotein involved in K transport
BKD09_RS14000	COG3384	dioxygenase
BKD09_RS14015	COG0590	tRNA wobble adenosine to inosine editing
BKD09_RS14020	COG4095	Psort location CytoplasmicMembrane, score
BKD09_RS14025	COG0297	glycogen (starch) synthase activity
BKD09_RS14030	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BKD09_RS14040	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKD09_RS14055	COG1116	anion transmembrane transporter activity
BKD09_RS14055	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKD09_RS14060	COG1960	acyl-CoA dehydrogenase activity
BKD09_RS14070	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKD09_RS14080	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BKD09_RS14085	COG0673	inositol 2-dehydrogenase activity
BKD09_RS14120	COG0559	Belongs to the binding-protein-dependent transport system permease family
BKD09_RS14130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKD09_RS14150	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BKD09_RS14155	COG3344	reverse transcriptase
BKD09_RS14220	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKD09_RS14225	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKD09_RS14275	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BKD09_RS14325	COG5489	Protein of unknown function (DUF736)
BKD09_RS14330	COG1476	TRANSCRIPTIONal
BKD09_RS14365	COG0681	Belongs to the peptidase S26 family
BKD09_RS14370	COG0739	heme binding
BKD09_RS14370	COG0741	lytic transglycosylase activity
BKD09_RS14370	COG1196	nuclear chromosome segregation
BKD09_RS14385	COG0739	heme binding
BKD09_RS14385	COG1196	nuclear chromosome segregation
BKD09_RS14385	COG0741	lytic transglycosylase activity
BKD09_RS14395	COG4974	Belongs to the 'phage' integrase family
BKD09_RS14415	COG0071	Belongs to the small heat shock protein (HSP20) family
BKD09_RS14465	COG0745	RESPONSE REGULATOR receiver
BKD09_RS14495	COG3293	Transposase
BKD09_RS14520	COG4566	intracellular signal transduction
BKD09_RS14570	COG0628	permease
BKD09_RS14650	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BKD09_RS14655	COG2943	transferase activity, transferring hexosyl groups
BKD09_RS14675	COG0596	Alpha beta hydrolase
BKD09_RS14695	COG0671	phosphoesterase, PA-phosphatase related
BKD09_RS14720	COG3685	Protein conserved in bacteria
BKD09_RS14830	COG0438	transferase activity, transferring glycosyl groups
BKD09_RS14845	COG2261	transglycosylase associated protein
BKD09_RS14865	COG0028	Belongs to the TPP enzyme family
BKD09_RS14935	COG2197	response regulator
BKD09_RS15015	COG1278	Cold shock
BKD09_RS15030	COG1295	ribonuclease BN
BKD09_RS15045	COG3685	Protein conserved in bacteria
BKD09_RS15050	COG0628	permease
BKD09_RS15085	COG0071	Belongs to the small heat shock protein (HSP20) family
BKD09_RS15150	COG3850	Histidine kinase
BKD09_RS15150	COG5002	protein histidine kinase activity
BKD09_RS15220	COG4566	intracellular signal transduction
BKD09_RS15225	COG4191	Histidine kinase
BKD09_RS15265	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BKD09_RS15270	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BKD09_RS15275	COG2080	2 iron, 2 sulfur cluster binding
BKD09_RS15280	COG0542	response to heat
BKD09_RS15300	COG0656	L-ascorbic acid biosynthetic process
BKD09_RS15305	COG3118	belongs to the thioredoxin family
BKD09_RS15320	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BKD09_RS15325	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BKD09_RS15330	COG2080	2 iron, 2 sulfur cluster binding
BKD09_RS15335	COG0783	Belongs to the Dps family
BKD09_RS15355	COG3920	Histidine kinase
BKD09_RS15370	COG1902	pentaerythritol trinitrate reductase activity
BKD09_RS15390	COG0484	heat shock protein binding
BKD09_RS15395	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BKD09_RS15400	COG0443	Heat shock 70 kDa protein
BKD09_RS15405	COG0071	Belongs to the small heat shock protein (HSP20) family
BKD09_RS15425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKD09_RS15430	COG0693	protein deglycase activity
BKD09_RS15450	COG3321	synthase
BKD09_RS15450	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS15450	COG0604	alcohol dehydrogenase
BKD09_RS15460	COG0628	permease
BKD09_RS15500	COG0039	L-malate dehydrogenase activity
BKD09_RS15505	COG4566	intracellular signal transduction
BKD09_RS15555	COG0071	Belongs to the small heat shock protein (HSP20) family
BKD09_RS15580	COG0459	protein refolding
BKD09_RS15585	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BKD09_RS15600	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BKD09_RS15625	COG0028	Belongs to the TPP enzyme family
BKD09_RS15640	COG0589	response to stress
BKD09_RS15660	COG1012	belongs to the aldehyde dehydrogenase family
BKD09_RS15665	COG2084	Dehydrogenase
BKD09_RS15670	COG3158	transport of potassium into the cell
BKD09_RS15705	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BKD09_RS15730	COG0670	Belongs to the BI1 family
BKD09_RS15735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKD09_RS15745	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BKD09_RS15755	COG0071	Belongs to the small heat shock protein (HSP20) family
BKD09_RS15760	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BKD09_RS15765	COG0459	protein refolding
BKD09_RS15780	COG0071	Belongs to the small heat shock protein (HSP20) family
BKD09_RS15785	COG0071	Belongs to the small heat shock protein (HSP20) family
BKD09_RS15795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKD09_RS15800	COG0583	DNA-binding transcription factor activity
BKD09_RS15805	COG2828	Protein conserved in bacteria
BKD09_RS15810	COG1301	dicarboxylic acid transport
BKD09_RS15820	COG0596	Alpha beta hydrolase
BKD09_RS15860	COG0671	phosphoesterase, PA-phosphatase related
BKD09_RS15865	COG1335	isochorismatase
BKD09_RS15870	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BKD09_RS15875	COG3685	Protein conserved in bacteria
BKD09_RS15880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKD09_RS15880	COG0723	plastoquinol--plastocyanin reductase activity
BKD09_RS15885	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BKD09_RS15885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKD09_RS15950	COG0071	Belongs to the small heat shock protein (HSP20) family
BKD09_RS15955	COG0071	Belongs to the small heat shock protein (HSP20) family
BKD09_RS16035	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BKD09_RS16110	COG0071	Belongs to the small heat shock protein (HSP20) family
BKD09_RS16160	COG1672	PFAM Archaeal ATPase
BKD09_RS16160	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BKD09_RS16180	COG4584	PFAM Integrase catalytic
BKD09_RS16185	COG1484	DNA-dependent DNA replication
BKD09_RS16215	COG0628	permease
BKD09_RS16295	COG3920	Histidine kinase
BKD09_RS16300	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BKD09_RS16315	COG3685	Protein conserved in bacteria
BKD09_RS16335	COG1295	ribonuclease BN
BKD09_RS16350	COG0671	phosphoesterase, PA-phosphatase related
BKD09_RS16420	COG0071	Belongs to the small heat shock protein (HSP20) family
BKD09_RS16595	COG0583	DNA-binding transcription factor activity
BKD09_RS16600	COG2828	Protein conserved in bacteria
BKD09_RS16605	COG1301	dicarboxylic acid transport
BKD09_RS16615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKD09_RS16625	COG1012	belongs to the aldehyde dehydrogenase family
BKD09_RS16640	COG1522	sequence-specific DNA binding
BKD09_RS16660	COG0601	transmembrane transport
BKD09_RS16665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKD09_RS16670	COG0445	tRNA wobble uridine modification
BKD09_RS16675	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BKD09_RS16680	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BKD09_RS16685	COG0156	8-amino-7-oxononanoate synthase activity
BKD09_RS16690	COG1063	alcohol dehydrogenase
BKD09_RS16715	COG0686	Belongs to the AlaDH PNT family
BKD09_RS16720	COG0277	FAD linked oxidase domain protein
BKD09_RS16725	COG1301	dicarboxylic acid transport
BKD09_RS16755	COG0583	DNA-binding transcription factor activity
BKD09_RS16765	COG1024	Enoyl-CoA hydratase
BKD09_RS16775	COG0471	metal ion transport
BKD09_RS16780	COG2814	Major facilitator Superfamily
BKD09_RS16790	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKD09_RS16800	COG4213	ABC transporter substrate-binding protein
BKD09_RS16805	COG1129	ABC transporter
BKD09_RS16810	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKD09_RS16815	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKD09_RS16825	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS16830	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BKD09_RS16850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BKD09_RS16870	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS16885	COG4106	trans-aconitate 2-methyltransferase activity
BKD09_RS16900	COG3220	belongs to the UPF0276 family
BKD09_RS16910	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BKD09_RS16930	COG4585	Histidine kinase
BKD09_RS16935	COG2197	response regulator
BKD09_RS16960	COG0628	permease
BKD09_RS16975	COG0670	Belongs to the BI1 family
BKD09_RS16985	COG0651	ATP synthesis coupled electron transport
BKD09_RS16990	COG1006	Multisubunit Na H antiporter MnhC subunit
BKD09_RS17000	COG1320	monovalent cation:proton antiporter activity
BKD09_RS17025	COG0471	metal ion transport
BKD09_RS17025	COG0490	domain, Protein
BKD09_RS17030	COG0490	domain, Protein
BKD09_RS17030	COG0471	metal ion transport
BKD09_RS17035	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKD09_RS17045	COG2066	Belongs to the glutaminase family
BKD09_RS17050	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BKD09_RS17065	COG2197	response regulator
BKD09_RS17080	COG0673	inositol 2-dehydrogenase activity
BKD09_RS17085	COG0673	inositol 2-dehydrogenase activity
BKD09_RS17095	COG0363	glucosamine-6-phosphate deaminase activity
BKD09_RS17110	COG1175	transmembrane transport
BKD09_RS17115	COG0395	ABC-type sugar transport system, permease component
BKD09_RS17120	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BKD09_RS17145	COG2020	methyltransferase activity
BKD09_RS17165	COG1032	radical SAM domain protein
BKD09_RS17205	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BKD09_RS17205	COG4797	methyltransferase
BKD09_RS17265	COG1716	ATPase activity
BKD09_RS17295	COG2815	serine threonine protein kinase
BKD09_RS17295	COG0515	serine threonine protein kinase
BKD09_RS17355	COG2197	response regulator
BKD09_RS17385	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BKD09_RS17390	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
BKD09_RS17410	COG3052	prosthetic group binding
BKD09_RS17430	COG2186	Transcriptional regulator
BKD09_RS17445	COG4172	Belongs to the ABC transporter superfamily
BKD09_RS17450	COG0405	Gamma-glutamyltransferase
BKD09_RS17455	COG0363	glucosamine-6-phosphate deaminase activity
BKD09_RS17460	COG1940	carbohydrate kinase activity
BKD09_RS17465	COG0747	negative chemotaxis
BKD09_RS17475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKD09_RS17480	COG0628	permease
BKD09_RS17485	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BKD09_RS17495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKD09_RS17500	COG4566	intracellular signal transduction
BKD09_RS17520	COG2985	domain, Protein
BKD09_RS17540	COG2985	domain, Protein
BKD09_RS17545	COG2985	domain, Protein
BKD09_RS17580	COG4191	Histidine kinase
BKD09_RS17585	COG3064	Membrane
BKD09_RS17610	COG2169	Transcriptional regulator
BKD09_RS17625	COG0596	Alpha beta hydrolase
BKD09_RS17630	COG2267	carboxylic ester hydrolase activity
BKD09_RS17660	COG0596	Alpha beta hydrolase
BKD09_RS17670	COG1764	response to oxidative stress
BKD09_RS17680	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKD09_RS17690	COG1566	PFAM secretion protein HlyD family protein
BKD09_RS17700	COG0656	L-ascorbic acid biosynthetic process
BKD09_RS17710	COG3181	Tripartite tricarboxylate transporter family receptor
BKD09_RS17715	COG2223	nitrite transmembrane transporter activity
BKD09_RS17840	COG0628	permease
BKD09_RS17845	COG2985	domain, Protein
BKD09_RS17905	COG0784	Response regulator, receiver
BKD09_RS17905	COG4191	Histidine kinase
BKD09_RS17910	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BKD09_RS17935	COG1116	anion transmembrane transporter activity
BKD09_RS17940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKD09_RS17960	COG1228	amidohydrolase
BKD09_RS17965	COG2986	histidine ammonia-lyase
BKD09_RS17970	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BKD09_RS17975	COG1309	transcriptional regulator
BKD09_RS18125	COG2197	response regulator
BKD09_RS18180	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKD09_RS18190	COG0723	plastoquinol--plastocyanin reductase activity
BKD09_RS18215	COG3791	Glutathione-dependent formaldehyde-activating
BKD09_RS18220	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BKD09_RS18245	COG3181	Tripartite tricarboxylate transporter family receptor
BKD09_RS18360	COG1131	(ABC) transporter
BKD09_RS18380	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BKD09_RS18385	COG2197	response regulator
BKD09_RS18390	COG3851	Histidine kinase
BKD09_RS18395	COG4773	Receptor
BKD09_RS18430	COG2723	6-phospho-beta-galactosidase activity
BKD09_RS18435	COG0183	Belongs to the thiolase family
BKD09_RS18440	COG0776	regulation of translation
BKD09_RS18445	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BKD09_RS18460	COG2095	MarC family integral membrane protein
BKD09_RS18465	COG0235	Class ii aldolase
BKD09_RS18495	COG0628	permease
BKD09_RS18530	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BKD09_RS18530	COG2080	2 iron, 2 sulfur cluster binding
BKD09_RS18550	COG1079	Belongs to the binding-protein-dependent transport system permease family
BKD09_RS18555	COG4603	Belongs to the binding-protein-dependent transport system permease family
BKD09_RS18560	COG3845	ABC transporter
BKD09_RS18575	COG3845	ABC transporter
BKD09_RS18585	COG1079	Belongs to the binding-protein-dependent transport system permease family
BKD09_RS18590	COG1079	Belongs to the binding-protein-dependent transport system permease family
BKD09_RS18610	COG1301	dicarboxylic acid transport
BKD09_RS18705	COG3300	MHYT domain
BKD09_RS18705	COG5001	Diguanylate cyclase
BKD09_RS18715	COG0010	Belongs to the arginase family
BKD09_RS18725	COG3258	Cytochrome c
BKD09_RS18795	COG3547	Transposase (IS116 IS110 IS902 family)
BKD09_RS18850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKD09_RS18885	COG2084	Dehydrogenase
BKD09_RS18895	COG0129	dihydroxy-acid dehydratase activity
BKD09_RS18900	COG1116	anion transmembrane transporter activity
BKD09_RS18905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKD09_RS18910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKD09_RS18920	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKD09_RS18930	COG0318	PFAM AMP-dependent synthetase and ligase
BKD09_RS18945	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS18950	COG1024	Enoyl-CoA hydratase
BKD09_RS18985	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BKD09_RS18985	COG0517	IMP dehydrogenase activity
BKD09_RS18985	COG0617	tRNA 3'-terminal CCA addition
BKD09_RS19020	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BKD09_RS19025	COG1127	ABC transporter
BKD09_RS19030	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BKD09_RS19030	COG3218	ABC-type transport auxiliary lipoprotein component
BKD09_RS19035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKD09_RS19045	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BKD09_RS19050	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BKD09_RS19065	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS19075	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BKD09_RS19075	COG2010	Cytochrome c
BKD09_RS19080	COG2080	2 iron, 2 sulfur cluster binding
BKD09_RS19085	COG3181	Tripartite tricarboxylate transporter family receptor
BKD09_RS19090	COG0243	molybdopterin cofactor binding
BKD09_RS19095	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BKD09_RS19250	COG3547	Transposase (IS116 IS110 IS902 family)
BKD09_RS19260	COG1696	Membrane protein involved in D-alanine export
BKD09_RS19340	COG0277	FAD linked oxidase domain protein
BKD09_RS19340	COG0247	lactate metabolic process
BKD09_RS19345	COG1802	Transcriptional regulator
BKD09_RS19350	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BKD09_RS19360	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BKD09_RS19365	COG1024	Enoyl-CoA hydratase
BKD09_RS19375	COG3181	Tripartite tricarboxylate transporter family receptor
BKD09_RS19410	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKD09_RS19445	COG0367	asparagine synthase
BKD09_RS19460	COG2226	methyltransferase
BKD09_RS19480	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BKD09_RS19500	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BKD09_RS19500	COG2755	lipolytic protein G-D-S-L family
BKD09_RS19510	COG0463	Glycosyl transferase, family 2
BKD09_RS19520	COG2226	methyltransferase
BKD09_RS19560	COG0367	asparagine synthase
BKD09_RS19590	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BKD09_RS19595	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BKD09_RS19600	COG0673	inositol 2-dehydrogenase activity
BKD09_RS19605	COG2192	nodulation
BKD09_RS19615	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BKD09_RS19630	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BKD09_RS19635	COG2942	2-epimerase
BKD09_RS19655	COG0559	Belongs to the binding-protein-dependent transport system permease family
BKD09_RS19660	COG1022	Amp-dependent synthetase and ligase
BKD09_RS19720	COG1137	ATPase activity
BKD09_RS19730	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BKD09_RS19745	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BKD09_RS19750	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BKD09_RS19770	COG1942	4-Oxalocrotonate Tautomerase
BKD09_RS19775	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS19780	COG0583	DNA-binding transcription factor activity
BKD09_RS19800	COG0528	UMP kinase activity
BKD09_RS19805	COG0528	UMP kinase activity
BKD09_RS19815	COG3344	reverse transcriptase
BKD09_RS19825	COG1132	(ABC) transporter
BKD09_RS19850	COG0859	PFAM glycosyl transferase family 9
BKD09_RS19860	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BKD09_RS19860	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BKD09_RS19885	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BKD09_RS19900	COG0662	Cupin 2, conserved barrel domain protein
BKD09_RS19900	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BKD09_RS19905	COG0673	inositol 2-dehydrogenase activity
BKD09_RS19930	COG0604	alcohol dehydrogenase
BKD09_RS19945	COG3909	cytochrome
BKD09_RS19975	COG2010	Cytochrome c
BKD09_RS19975	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BKD09_RS19980	COG3547	Transposase (IS116 IS110 IS902 family)
BKD09_RS19995	COG2321	neutral zinc metallopeptidase
BKD09_RS20000	COG2433	Pfam Transposase IS66
BKD09_RS20010	COG0351	phosphomethylpyrimidine kinase
BKD09_RS20035	COG1283	sodium-dependent phosphate transmembrane transporter activity
BKD09_RS20045	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS20055	COG2814	Major facilitator Superfamily
BKD09_RS20060	COG4948	Mandelate Racemase Muconate Lactonizing
BKD09_RS20065	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BKD09_RS20070	COG1127	ABC transporter
BKD09_RS20075	COG3218	ABC-type transport auxiliary lipoprotein component
BKD09_RS20075	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BKD09_RS20095	COG0633	Ferredoxin
BKD09_RS20105	COG0492	ferredoxin-NADP+ reductase activity
BKD09_RS20125	COG4774	siderophore transport
BKD09_RS20130	COG1733	regulation of RNA biosynthetic process
BKD09_RS20145	COG2205	protein histidine kinase activity
BKD09_RS20150	COG0745	RESPONSE REGULATOR receiver
BKD09_RS20165	COG2721	sulfolactate sulfo-lyase activity
BKD09_RS20170	COG1012	belongs to the aldehyde dehydrogenase family
BKD09_RS20180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKD09_RS20185	COG0583	DNA-binding transcription factor activity
BKD09_RS20190	COG2271	Major facilitator Superfamily
BKD09_RS20205	COG3685	Protein conserved in bacteria
BKD09_RS20210	COG0477	Major facilitator Superfamily
BKD09_RS20215	COG3300	MHYT domain
BKD09_RS20215	COG5001	Diguanylate cyclase
BKD09_RS20235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKD09_RS20245	COG0589	response to stress
BKD09_RS20255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKD09_RS20260	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKD09_RS20265	COG1749	Flagellar hook protein flgE
BKD09_RS20300	COG5443	negative regulation of bacterial-type flagellum assembly
BKD09_RS20305	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BKD09_RS20310	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BKD09_RS20335	COG1706	bacterial-type flagellum-dependent cell motility
BKD09_RS20345	COG1733	regulation of RNA biosynthetic process
BKD09_RS20350	COG2910	NAD(P)H-binding
BKD09_RS20360	COG1733	regulation of RNA biosynthetic process
BKD09_RS20365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKD09_RS20375	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BKD09_RS20385	COG4786	Flagellar basal body rod
BKD09_RS20390	COG4786	Flagellar basal body rod
BKD09_RS20450	COG1338	Plays a role in the flagellum-specific transport system
BKD09_RS20465	COG1558	bacterial-type flagellum-dependent cell motility
BKD09_RS20470	COG1677	Flagellar hook-basal body complex protein FliE
BKD09_RS20475	COG1987	bacterial-type flagellum assembly
BKD09_RS20480	COG1684	flagellar biosynthetic protein fliR
BKD09_RS20515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKD09_RS20520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKD09_RS20555	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BKD09_RS20555	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BKD09_RS20575	COG2917	probably involved in intracellular septation
BKD09_RS20625	COG1178	ABC-type Fe3 transport system permease component
BKD09_RS20630	COG3842	ATPase activity
BKD09_RS20640	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BKD09_RS20645	COG0066	3-isopropylmalate dehydratase activity
BKD09_RS20650	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BKD09_RS20655	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BKD09_RS20700	COG1137	ATPase activity
BKD09_RS20710	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS20720	COG1129	ABC transporter
BKD09_RS20725	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKD09_RS20735	COG1349	DNA-binding transcription factor activity
BKD09_RS20740	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BKD09_RS20745	COG1012	belongs to the aldehyde dehydrogenase family
BKD09_RS20750	COG4154	Belongs to the RbsD FucU family
BKD09_RS20760	COG1175	transmembrane transport
BKD09_RS20765	COG0395	ABC-type sugar transport system, permease component
BKD09_RS20775	COG3842	ATPase activity
BKD09_RS20895	COG0463	Glycosyl transferase, family 2
BKD09_RS20895	COG1216	Glycosyl transferase, family 2
BKD09_RS20915	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BKD09_RS20925	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BKD09_RS20925	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BKD09_RS20930	COG0509	glycine decarboxylation via glycine cleavage system
BKD09_RS20935	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BKD09_RS20940	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BKD09_RS20945	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKD09_RS20955	COG0538	isocitrate dehydrogenase activity
BKD09_RS20960	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BKD09_RS20980	COG0604	alcohol dehydrogenase
BKD09_RS20985	COG2020	methyltransferase activity
BKD09_RS20995	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
BKD09_RS21005	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BKD09_RS21010	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BKD09_RS21015	COG0598	Magnesium transport protein CorA
BKD09_RS21020	COG0047	phosphoribosylformylglycinamidine synthase activity
BKD09_RS21025	COG3181	Tripartite tricarboxylate transporter family receptor
BKD09_RS21045	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BKD09_RS21060	COG0596	Alpha beta hydrolase
BKD09_RS21080	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BKD09_RS21085	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BKD09_RS21090	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BKD09_RS21095	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BKD09_RS21115	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BKD09_RS21155	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BKD09_RS21160	COG0318	PFAM AMP-dependent synthetase and ligase
BKD09_RS21185	COG1473	amidohydrolase
BKD09_RS21190	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BKD09_RS21195	COG1309	transcriptional regulator
BKD09_RS21205	COG1234	tRNA 3'-trailer cleavage
BKD09_RS21245	COG0515	serine threonine protein kinase
BKD09_RS21245	COG2815	serine threonine protein kinase
BKD09_RS21280	COG0784	Response regulator, receiver
BKD09_RS21280	COG4191	Histidine kinase
BKD09_RS21285	COG2204	response regulator
BKD09_RS21325	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKD09_RS21330	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BKD09_RS21335	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BKD09_RS21370	COG3608	succinylglutamate desuccinylase aspartoacylase
BKD09_RS21370	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BKD09_RS21395	COG0640	Transcriptional regulator
BKD09_RS21410	COG1131	(ABC) transporter
BKD09_RS21415	COG0842	Transport permease protein
BKD09_RS21430	COG2188	Transcriptional regulator
BKD09_RS21435	COG2814	Major facilitator Superfamily
BKD09_RS21445	COG0384	phenazine biosynthesis protein PhzF
BKD09_RS21525	COG1131	(ABC) transporter
BKD09_RS21550	COG1335	isochorismatase
BKD09_RS21580	COG0681	Belongs to the peptidase S26 family
BKD09_RS21585	COG0459	protein refolding
BKD09_RS21590	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BKD09_RS21595	COG5425	PFAM Usg family protein
BKD09_RS21605	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BKD09_RS21620	COG4221	oxidoreductase activity
BKD09_RS21640	COG1305	Transglutaminase-like
BKD09_RS21650	COG2308	Evidence 4 Homologs of previously reported genes of
BKD09_RS21655	COG1058	Belongs to the CinA family
BKD09_RS21655	COG1546	Belongs to the CinA family
BKD09_RS21660	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BKD09_RS21675	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BKD09_RS21680	COG0625	glutathione transferase activity
BKD09_RS21690	COG3321	synthase
BKD09_RS21690	COG0604	alcohol dehydrogenase
BKD09_RS21695	COG1024	Enoyl-CoA hydratase
BKD09_RS21700	COG0154	amidase activity
BKD09_RS21705	COG1473	amidohydrolase
BKD09_RS21715	COG4172	Belongs to the ABC transporter superfamily
BKD09_RS21720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKD09_RS21725	COG0601	transmembrane transport
BKD09_RS21740	COG0747	negative chemotaxis
BKD09_RS21760	COG1024	Enoyl-CoA hydratase
BKD09_RS21780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKD09_RS21795	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BKD09_RS21850	COG3833	ABC-type maltose transport systems, permease component
BKD09_RS21855	COG1176	ABC-type spermidine putrescine transport system, permease component I
BKD09_RS21925	COG1063	alcohol dehydrogenase
BKD09_RS21960	COG0513	Belongs to the DEAD box helicase family
BKD09_RS22005	COG0517	IMP dehydrogenase activity
BKD09_RS22010	COG1752	Esterase of the alpha-beta hydrolase superfamily
BKD09_RS22050	COG2020	methyltransferase activity
BKD09_RS22065	COG5001	Diguanylate cyclase
BKD09_RS22080	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BKD09_RS22085	COG2814	Major facilitator Superfamily
BKD09_RS22105	COG0531	amino acid
BKD09_RS22120	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BKD09_RS22135	COG0302	gtp cyclohydrolase
BKD09_RS22140	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BKD09_RS22170	COG3655	Transcriptional regulator
BKD09_RS22180	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BKD09_RS22240	COG0840	transmembrane signaling receptor activity
BKD09_RS22270	COG0861	Integral membrane protein TerC family
BKD09_RS22305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BKD09_RS22325	COG0477	Major facilitator Superfamily
BKD09_RS22335	COG0402	S-adenosylhomocysteine deaminase activity
BKD09_RS22345	COG0210	DNA helicase
BKD09_RS22355	COG3795	YCII-related domain
BKD09_RS22375	COG4191	Histidine kinase
BKD09_RS22375	COG0784	Response regulator, receiver
BKD09_RS22400	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKD09_RS22440	COG0577	efflux transmembrane transporter activity
BKD09_RS22440	COG1136	(ABC) transporter
BKD09_RS22510	COG2304	oxidoreductase activity
BKD09_RS22530	COG3038	cytochrome b561
BKD09_RS22555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKD09_RS22570	COG3246	L-lysine catabolic process to acetate
BKD09_RS22580	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BKD09_RS22585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKD09_RS22605	COG1960	acyl-CoA dehydrogenase activity
BKD09_RS22630	COG1309	transcriptional regulator
BKD09_RS22645	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS22650	COG0406	alpha-ribazole phosphatase activity
BKD09_RS22655	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS22670	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BKD09_RS22675	COG0250	Participates in transcription elongation, termination and antitermination
BKD09_RS22680	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BKD09_RS22685	COG0081	regulation of translation
BKD09_RS22690	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKD09_RS22695	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BKD09_RS22700	COG0222	ribosome binding
BKD09_RS22705	COG0085	RNA polymerase activity
BKD09_RS22710	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BKD09_RS22715	COG1231	oxidoreductase activity
BKD09_RS22720	COG1132	(ABC) transporter
BKD09_RS22725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKD09_RS22730	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BKD09_RS22735	COG0049	tRNA binding
BKD09_RS22740	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BKD09_RS22745	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BKD09_RS22750	COG0051	transcription antitermination factor activity, RNA binding
BKD09_RS22755	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BKD09_RS22760	COG0088	Forms part of the polypeptide exit tunnel
BKD09_RS22765	COG0089	rRNA binding
BKD09_RS22770	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BKD09_RS22775	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BKD09_RS22780	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BKD09_RS22785	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BKD09_RS22790	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BKD09_RS22795	COG0255	Belongs to the universal ribosomal protein uL29 family
BKD09_RS22800	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BKD09_RS22805	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BKD09_RS22810	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BKD09_RS22815	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BKD09_RS22820	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BKD09_RS22825	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BKD09_RS22830	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BKD09_RS22835	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BKD09_RS22840	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BKD09_RS22845	COG1841	ribosomal large subunit assembly
BKD09_RS22850	COG0200	Binds to the 23S rRNA
BKD09_RS22860	COG0563	adenylate kinase activity
BKD09_RS22865	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BKD09_RS22870	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BKD09_RS22875	COG0202	RNA polymerase activity
BKD09_RS22880	COG0203	ribosomal protein L17
BKD09_RS22890	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS22900	COG1733	regulation of RNA biosynthetic process
BKD09_RS22915	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BKD09_RS22940	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BKD09_RS22970	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BKD09_RS22985	COG2319	Wd-40 repeat
BKD09_RS22985	COG3903	Transcriptional regulator
BKD09_RS23045	COG2860	membrane
BKD09_RS23075	COG2030	dehydratase
BKD09_RS23080	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS23190	COG0415	Belongs to the DNA photolyase family
BKD09_RS23200	COG0450	alkyl hydroperoxide reductase
BKD09_RS23220	COG4221	oxidoreductase activity
BKD09_RS23250	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS23280	COG2197	response regulator
BKD09_RS23295	COG1063	alcohol dehydrogenase
BKD09_RS23300	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS23305	COG4948	Mandelate Racemase Muconate Lactonizing
BKD09_RS23315	COG2271	Major facilitator Superfamily
BKD09_RS23340	COG0784	Response regulator, receiver
BKD09_RS23340	COG4191	Histidine kinase
BKD09_RS23350	COG4770	biotin carboxylase activity
BKD09_RS23355	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BKD09_RS23360	COG1254	Belongs to the acylphosphatase family
BKD09_RS23365	COG0784	Response regulator, receiver
BKD09_RS23365	COG4191	Histidine kinase
BKD09_RS23380	COG1090	epimerase
BKD09_RS23390	COG0583	DNA-binding transcription factor activity
BKD09_RS23400	COG0305	Participates in initiation and elongation during chromosome replication
BKD09_RS23405	COG0321	lipoyl(octanoyl) transferase activity
BKD09_RS23440	COG0523	cobalamin synthesis protein
BKD09_RS23455	COG0726	polysaccharide deacetylase
BKD09_RS23465	COG2239	Acts as a magnesium transporter
BKD09_RS23475	COG0656	L-ascorbic acid biosynthetic process
BKD09_RS23530	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BKD09_RS23555	COG1686	Belongs to the peptidase S11 family
BKD09_RS23570	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BKD09_RS23580	COG3344	reverse transcriptase
BKD09_RS23590	COG2814	Major facilitator Superfamily
BKD09_RS23595	COG0667	Aldo Keto reductase
BKD09_RS23610	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BKD09_RS23675	COG1720	tRNA m6t6A37 methyltransferase activity
BKD09_RS23680	COG0537	adenosine 5'-monophosphoramidase activity
BKD09_RS23720	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BKD09_RS23730	COG0784	Response regulator, receiver
BKD09_RS23760	COG3034	peptidoglycan biosynthetic process
BKD09_RS23765	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS23785	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BKD09_RS23795	COG1473	amidohydrolase
BKD09_RS23820	COG0557	exoribonuclease II activity
BKD09_RS23825	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BKD09_RS23840	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS23850	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BKD09_RS23855	COG1733	regulation of RNA biosynthetic process
BKD09_RS23860	COG0758	DNA mediated transformation
BKD09_RS23875	COG0154	amidase activity
BKD09_RS23885	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BKD09_RS23890	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BKD09_RS23895	COG0540	Belongs to the ATCase OTCase family
BKD09_RS23915	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BKD09_RS23930	COG0583	DNA-binding transcription factor activity
BKD09_RS23935	COG2070	2-Nitropropane dioxygenase
BKD09_RS23940	COG2070	2-Nitropropane dioxygenase
BKD09_RS23945	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BKD09_RS23955	COG0154	amidase activity
BKD09_RS23965	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BKD09_RS24090	COG0582	viral genome integration into host DNA
BKD09_RS24105	COG0741	lytic transglycosylase activity
BKD09_RS24110	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKD09_RS24115	COG1970	mechanosensitive ion channel activity
BKD09_RS24120	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BKD09_RS24140	COG1758	RNA polymerase activity
BKD09_RS24150	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BKD09_RS24155	COG0736	holo-[acyl-carrier-protein] synthase activity
BKD09_RS24160	COG0681	Belongs to the peptidase S26 family
BKD09_RS24165	COG0571	ribonuclease III activity
BKD09_RS24170	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BKD09_RS24180	COG1381	Involved in DNA repair and RecF pathway recombination
BKD09_RS24190	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BKD09_RS24195	COG0747	negative chemotaxis
BKD09_RS24225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKD09_RS24230	COG0697	spore germination
BKD09_RS24245	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BKD09_RS24265	COG1914	H( )-stimulated, divalent metal cation uptake system
BKD09_RS24270	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BKD09_RS24280	COG0113	porphobilinogen synthase activity
BKD09_RS24305	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BKD09_RS24310	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BKD09_RS24315	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BKD09_RS24315	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BKD09_RS24325	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BKD09_RS24330	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BKD09_RS24335	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BKD09_RS24345	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BKD09_RS24350	COG3344	reverse transcriptase
BKD09_RS24375	COG0416	fatty acid biosynthetic process
BKD09_RS24380	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKD09_RS24385	COG0776	regulation of translation
BKD09_RS24440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKD09_RS24505	COG0657	acetylesterase activity
BKD09_RS24515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKD09_RS24535	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BKD09_RS24565	COG3268	Saccharopine dehydrogenase
BKD09_RS24570	COG3268	Saccharopine dehydrogenase
BKD09_RS24575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKD09_RS24580	COG1846	Transcriptional regulator
BKD09_RS24595	COG0438	transferase activity, transferring glycosyl groups
BKD09_RS24620	COG1612	heme a metabolic process
BKD09_RS24640	COG1024	Enoyl-CoA hydratase
BKD09_RS24650	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BKD09_RS24655	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BKD09_RS24685	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BKD09_RS24705	COG0330	HflC and HflK could
BKD09_RS24710	COG0252	asparaginase activity
BKD09_RS24715	COG0174	glutamine synthetase
BKD09_RS24720	COG0347	Belongs to the P(II) protein family
BKD09_RS24725	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BKD09_RS24725	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BKD09_RS24745	COG0544	peptidyl-prolyl cis-trans isomerase activity
BKD09_RS24750	COG0740	serine-type endopeptidase activity
BKD09_RS24755	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BKD09_RS24760	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BKD09_RS24780	COG2226	methyltransferase
BKD09_RS24815	COG2195	Cleaves the N-terminal amino acid of tripeptides
BKD09_RS24820	COG0776	regulation of translation
BKD09_RS24835	COG2814	Major facilitator Superfamily
BKD09_RS24850	COG4774	siderophore transport
BKD09_RS24870	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BKD09_RS24880	COG0649	NAD binding
BKD09_RS24890	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BKD09_RS24900	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BKD09_RS24910	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BKD09_RS24915	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BKD09_RS24925	COG0713	ATP synthesis coupled electron transport
BKD09_RS24940	COG1007	ATP synthesis coupled electron transport
BKD09_RS24955	COG0346	lactoylglutathione lyase activity
BKD09_RS24980	COG0747	negative chemotaxis
BKD09_RS24990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKD09_RS24995	COG0444	Belongs to the ABC transporter superfamily
BKD09_RS25025	COG0583	DNA-binding transcription factor activity
BKD09_RS25035	COG0251	oxidation-reduction process
BKD09_RS25045	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKD09_RS25050	COG1129	ABC transporter
BKD09_RS25070	COG4774	siderophore transport
BKD09_RS25080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKD09_RS25105	COG0442	prolyl-tRNA aminoacylation
BKD09_RS25115	COG1136	(ABC) transporter
BKD09_RS25160	COG3181	Tripartite tricarboxylate transporter family receptor
BKD09_RS25175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKD09_RS25180	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKD09_RS25190	COG2814	Major facilitator Superfamily
BKD09_RS25250	COG0052	Belongs to the universal ribosomal protein uS2 family
BKD09_RS25255	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BKD09_RS25260	COG0528	UMP kinase activity
BKD09_RS25265	COG0233	cytoplasmic translational termination
BKD09_RS25270	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BKD09_RS25280	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BKD09_RS25285	COG0750	zinc metalloprotease
BKD09_RS25290	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BKD09_RS25295	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BKD09_RS25300	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BKD09_RS25310	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BKD09_RS25320	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BKD09_RS25325	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS25330	COG3842	ATPase activity
BKD09_RS25335	COG0395	ABC-type sugar transport system, permease component
BKD09_RS25340	COG1175	transmembrane transport
BKD09_RS25360	COG0372	Belongs to the citrate synthase family
BKD09_RS25365	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BKD09_RS25370	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BKD09_RS25405	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BKD09_RS25410	COG0303	'Molybdopterin
BKD09_RS25420	COG1011	Hydrolase
BKD09_RS25430	COG0793	Belongs to the peptidase S41A family
BKD09_RS25435	COG5001	Diguanylate cyclase
BKD09_RS25435	COG3300	MHYT domain
BKD09_RS25460	COG0315	cyclic pyranopterin monophosphate synthase activity
BKD09_RS25465	COG0134	indole-3-glycerol-phosphate synthase activity
BKD09_RS25470	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BKD09_RS25475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BKD09_RS25480	COG0149	triose-phosphate isomerase activity
BKD09_RS25490	COG0504	CTP synthase activity
BKD09_RS25495	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BKD09_RS25500	COG2205	protein histidine kinase activity
BKD09_RS25505	COG0745	RESPONSE REGULATOR receiver
BKD09_RS25515	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BKD09_RS25520	COG2814	Major facilitator Superfamily
BKD09_RS25535	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKD09_RS25540	COG3842	ATPase activity
BKD09_RS25565	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BKD09_RS25575	COG0148	phosphopyruvate hydratase activity
BKD09_RS25590	COG0431	NADPH-dependent FMN reductase
BKD09_RS25605	COG1012	belongs to the aldehyde dehydrogenase family
BKD09_RS25615	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BKD09_RS25620	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKD09_RS25620	COG0022	dehydrogenase e1 component
BKD09_RS25635	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKD09_RS25645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BKD09_RS25650	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BKD09_RS25660	COG4566	intracellular signal transduction
BKD09_RS25665	COG4566	intracellular signal transduction
BKD09_RS25670	COG4191	Histidine kinase
BKD09_RS25685	COG0741	lytic transglycosylase activity
BKD09_RS25745	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BKD09_RS25745	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BKD09_RS25750	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BKD09_RS25760	COG0129	dihydroxy-acid dehydratase activity
BKD09_RS25765	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BKD09_RS25770	COG0708	Exodeoxyribonuclease III
BKD09_RS25775	COG0784	Response regulator, receiver
BKD09_RS25775	COG2198	Histidine kinase
BKD09_RS25775	COG5002	protein histidine kinase activity
BKD09_RS25790	COG0346	lactoylglutathione lyase activity
BKD09_RS25800	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BKD09_RS25805	COG0018	arginyl-trna synthetase
BKD09_RS25815	COG1472	Belongs to the glycosyl hydrolase 3 family
BKD09_RS25820	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BKD09_RS25825	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BKD09_RS25830	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BKD09_RS25835	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BKD09_RS25840	COG0805	protein transport
BKD09_RS25845	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BKD09_RS25855	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BKD09_RS25865	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BKD09_RS25875	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BKD09_RS25880	COG3119	arylsulfatase activity
BKD09_RS25885	COG3119	arylsulfatase activity
BKD09_RS25910	COG2095	MarC family integral membrane protein
BKD09_RS25915	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BKD09_RS25935	COG1862	Preprotein translocase
BKD09_RS25940	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BKD09_RS25955	COG1562	ergosterol biosynthetic process
BKD09_RS25960	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BKD09_RS25965	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BKD09_RS25970	COG0583	DNA-binding transcription factor activity
BKD09_RS25975	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKD09_RS25980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BKD09_RS25995	COG2340	Cysteine-rich secretory protein family
BKD09_RS26005	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BKD09_RS26100	COG0546	phosphoglycolate phosphatase activity
BKD09_RS26120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BKD09_RS26145	COG0629	single-stranded DNA binding
BKD09_RS26155	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BKD09_RS26170	COG4774	siderophore transport
BKD09_RS26175	COG3158	transport of potassium into the cell
BKD09_RS26185	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BKD09_RS26205	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BKD09_RS26210	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BKD09_RS26220	COG1309	transcriptional regulator
BKD09_RS26255	COG0765	amino acid transport
BKD09_RS26260	COG0765	amino acid transport
BKD09_RS26275	COG0583	DNA-binding transcription factor activity
BKD09_RS26305	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BKD09_RS26330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKD09_RS26345	COG0628	permease
BKD09_RS26440	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BKD09_RS26455	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BKD09_RS26475	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BKD09_RS26500	COG4221	oxidoreductase activity
BKD09_RS26545	COG0679	Auxin Efflux Carrier
BKD09_RS26550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKD09_RS26555	COG1183	phosphatidylcholine synthase activity
BKD09_RS26560	COG1253	flavin adenine dinucleotide binding
BKD09_RS26570	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BKD09_RS26590	COG0789	Transcriptional regulator
BKD09_RS26595	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKD09_RS26600	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BKD09_RS26605	COG3707	response regulator
BKD09_RS26610	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKD09_RS26615	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BKD09_RS26620	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BKD09_RS26625	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BKD09_RS26630	COG1984	allophanate hydrolase subunit 2
BKD09_RS26640	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BKD09_RS26640	COG0473	3-isopropylmalate dehydrogenase activity
BKD09_RS26680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKD09_RS26695	COG1175	transmembrane transport
BKD09_RS26730	COG1335	isochorismatase
BKD09_RS26740	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BKD09_RS26740	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BKD09_RS26760	COG0444	Belongs to the ABC transporter superfamily
BKD09_RS26770	COG0601	transmembrane transport
BKD09_RS26775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKD09_RS26800	COG0129	dihydroxy-acid dehydratase activity
BKD09_RS26825	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BKD09_RS26830	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BKD09_RS26840	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BKD09_RS26845	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BKD09_RS26860	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BKD09_RS26880	COG2072	flavoprotein involved in K transport
BKD09_RS26890	COG1672	PFAM Archaeal ATPase
BKD09_RS26890	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BKD09_RS26970	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BKD09_RS27000	COG2267	carboxylic ester hydrolase activity
BKD09_RS27005	COG1686	Belongs to the peptidase S11 family
BKD09_RS27010	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BKD09_RS27020	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKD09_RS27025	COG0084	hydrolase, TatD family'
BKD09_RS27030	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BKD09_RS27030	COG0321	lipoyl(octanoyl) transferase activity
BKD09_RS27035	COG0318	PFAM AMP-dependent synthetase and ligase
BKD09_RS27040	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BKD09_RS27045	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BKD09_RS27050	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BKD09_RS27215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKD09_RS27220	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BKD09_RS27270	COG0583	DNA-binding transcription factor activity
BKD09_RS27280	COG0583	DNA-binding transcription factor activity
BKD09_RS27285	COG1335	isochorismatase
BKD09_RS27300	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BKD09_RS27335	COG1464	Belongs to the NlpA lipoprotein family
BKD09_RS27340	COG2011	ABC-type metal ion transport system permease component
BKD09_RS27345	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BKD09_RS27350	COG0471	metal ion transport
BKD09_RS27355	COG1024	Enoyl-CoA hydratase
BKD09_RS27375	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BKD09_RS27380	COG3956	TIGRFAM MazG family protein
BKD09_RS27390	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BKD09_RS27395	COG1923	regulation of RNA biosynthetic process
BKD09_RS27400	COG2204	response regulator
BKD09_RS27405	COG5000	phosphorelay sensor kinase activity
BKD09_RS27430	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BKD09_RS27430	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BKD09_RS27435	COG1058	Belongs to the CinA family
BKD09_RS27435	COG1546	Belongs to the CinA family
BKD09_RS27445	COG2863	cytochrome
BKD09_RS27465	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BKD09_RS27470	COG2863	cytochrome
BKD09_RS27475	COG2867	negative regulation of translational initiation
BKD09_RS27480	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BKD09_RS27485	COG2094	Belongs to the DNA glycosylase MPG family
BKD09_RS27490	COG0525	valine-tRNA ligase activity
BKD09_RS27505	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BKD09_RS27520	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BKD09_RS27540	COG1566	PFAM secretion protein HlyD family protein
BKD09_RS27555	COG3119	arylsulfatase activity
BKD09_RS27585	COG0714	Associated with various cellular activities
BKD09_RS27590	COG3119	arylsulfatase activity
BKD09_RS27595	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BKD09_RS27620	COG2268	Band 7 protein
BKD09_RS27635	COG0251	oxidation-reduction process
BKD09_RS27650	COG1126	abc transporter atp-binding protein
BKD09_RS27695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKD09_RS27710	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BKD09_RS27720	COG1126	abc transporter atp-binding protein
BKD09_RS27725	COG0765	amino acid transport
BKD09_RS27730	COG4597	amino acid ABC transporter
BKD09_RS27735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKD09_RS27740	COG0626	cystathionine gamma-synthase activity
BKD09_RS27745	COG1283	sodium-dependent phosphate transmembrane transporter activity
BKD09_RS27755	COG0463	Glycosyl transferase, family 2
BKD09_RS27760	COG0671	phosphoesterase, PA-phosphatase related
BKD09_RS27770	COG4953	penicillin-binding protein 1C
BKD09_RS27775	COG2373	Large extracellular alpha-helical protein
BKD09_RS27825	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BKD09_RS27850	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BKD09_RS27855	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BKD09_RS27860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKD09_RS27870	COG4770	biotin carboxylase activity
BKD09_RS27875	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BKD09_RS27880	COG1960	acyl-CoA dehydrogenase activity
BKD09_RS27895	COG1522	sequence-specific DNA binding
BKD09_RS27940	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BKD09_RS27975	COG0776	regulation of translation
BKD09_RS28060	COG0625	glutathione transferase activity
BKD09_RS28180	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BKD09_RS28200	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BKD09_RS28215	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKD09_RS28255	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BKD09_RS28260	COG0840	transmembrane signaling receptor activity
BKD09_RS28310	COG0583	DNA-binding transcription factor activity
BKD09_RS28315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKD09_RS28320	COG1494	fructose-1,6-bisphosphatase
BKD09_RS28330	COG0436	Aminotransferase
BKD09_RS28340	COG3243	poly(R)-hydroxyalkanoic acid synthase
BKD09_RS28350	COG4106	trans-aconitate 2-methyltransferase activity
BKD09_RS28355	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BKD09_RS28370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKD09_RS28375	COG0586	Pfam SNARE associated Golgi protein
BKD09_RS28380	COG0187	DNA topoisomerase II activity
BKD09_RS28405	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS28435	COG0513	Belongs to the DEAD box helicase family
BKD09_RS28445	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BKD09_RS28455	COG0316	Belongs to the HesB IscA family
BKD09_RS28465	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BKD09_RS28470	COG0719	Fe-S assembly protein
BKD09_RS28475	COG0396	ATPase activity
BKD09_RS28480	COG0719	Fe-S assembly protein
BKD09_RS28485	COG1104	cysteine desulfurase activity
BKD09_RS28490	COG2945	thiolester hydrolase activity
BKD09_RS28505	COG0625	glutathione transferase activity
BKD09_RS28510	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BKD09_RS28515	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BKD09_RS28520	COG2271	Major facilitator Superfamily
BKD09_RS28525	COG2259	Doxx family
BKD09_RS28545	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BKD09_RS28550	COG0739	heme binding
BKD09_RS28565	COG0438	transferase activity, transferring glycosyl groups
BKD09_RS28595	COG0697	spore germination
BKD09_RS28605	COG2084	Dehydrogenase
BKD09_RS28615	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BKD09_RS28625	COG1530	ribonuclease E activity
BKD09_RS28625	COG1530	ribonuclease E activity
BKD09_RS28630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKD09_RS28645	COG1301	dicarboxylic acid transport
BKD09_RS28650	COG1268	BioY protein
BKD09_RS28655	COG0436	Aminotransferase
BKD09_RS28675	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BKD09_RS28680	COG0511	ligase activity, forming carbon-carbon bonds
BKD09_RS28685	COG0439	Biotin carboxylase
BKD09_RS28690	COG5002	protein histidine kinase activity
BKD09_RS28695	COG0784	Response regulator, receiver
BKD09_RS28700	COG3920	Histidine kinase
BKD09_RS28705	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BKD09_RS28715	COG0657	acetylesterase activity
BKD09_RS28725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKD09_RS28730	COG2226	methyltransferase
BKD09_RS28760	COG4191	Histidine kinase
BKD09_RS28760	COG0784	Response regulator, receiver
BKD09_RS28775	COG0697	spore germination
BKD09_RS28780	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BKD09_RS28855	COG2824	Alkylphosphonate utilization operon protein PhnA
BKD09_RS28895	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BKD09_RS28920	COG1309	transcriptional regulator
BKD09_RS28960	COG1376	ErfK ybiS ycfS ynhG family protein
BKD09_RS28975	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS28995	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BKD09_RS29000	COG2894	cell division
BKD09_RS29005	COG0850	regulation of cytokinetic process
BKD09_RS29010	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BKD09_RS29015	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BKD09_RS29020	COG3119	arylsulfatase activity
BKD09_RS29030	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BKD09_RS29040	COG1309	transcriptional regulator
BKD09_RS29045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKD09_RS29080	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BKD09_RS29110	COG2207	Transcriptional regulator
BKD09_RS29140	COG0657	acetylesterase activity
BKD09_RS29170	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BKD09_RS29180	COG0584	glycerophosphoryl diester phosphodiesterase
BKD09_RS29185	COG0488	(ABC) transporter
BKD09_RS29230	COG0174	glutamine synthetase
BKD09_RS29250	COG2365	Tyrosine phosphatase family
BKD09_RS29255	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS29290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BKD09_RS29300	COG3483	tryptophan 2,3-dioxygenase activity
BKD09_RS29310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKD09_RS29345	COG3045	CreA protein
BKD09_RS29355	COG0386	Belongs to the glutathione peroxidase family
BKD09_RS29370	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BKD09_RS29380	COG0281	malic enzyme
BKD09_RS29380	COG0280	phosphate acetyltransferase
BKD09_RS29390	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BKD09_RS29395	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BKD09_RS29400	COG1943	Transposase
BKD09_RS29415	COG1175	transmembrane transport
BKD09_RS29435	COG1176	ABC-type spermidine putrescine transport system, permease component I
BKD09_RS29440	COG3842	ATPase activity
BKD09_RS29450	COG2186	Transcriptional regulator
BKD09_RS29465	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BKD09_RS29470	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BKD09_RS29475	COG2271	Major facilitator Superfamily
BKD09_RS29515	COG1278	Cold shock
BKD09_RS29520	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BKD09_RS29525	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BKD09_RS29540	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BKD09_RS29545	COG0248	Ppx GppA phosphatase
BKD09_RS29555	COG4774	siderophore transport
BKD09_RS29560	COG0861	Integral membrane protein TerC family
BKD09_RS29565	COG0105	UTP biosynthetic process
BKD09_RS29580	COG0488	(ABC) transporter
BKD09_RS29615	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BKD09_RS29620	COG0795	lipopolysaccharide-transporting ATPase activity
BKD09_RS29630	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BKD09_RS29640	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BKD09_RS29645	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BKD09_RS29700	COG0194	GDP metabolic process
BKD09_RS29705	COG1561	YicC-like family, N-terminal region
BKD09_RS29710	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BKD09_RS29715	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BKD09_RS29720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKD09_RS29730	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BKD09_RS29745	COG0360	Binds together with S18 to 16S ribosomal RNA
BKD09_RS29750	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BKD09_RS29760	COG0359	binds to the 23S rRNA
BKD09_RS29785	COG0305	Participates in initiation and elongation during chromosome replication
BKD09_RS29790	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BKD09_RS29825	COG2186	Transcriptional regulator
BKD09_RS29830	COG2084	Dehydrogenase
BKD09_RS29835	COG0765	amino acid transport
BKD09_RS29840	COG0765	amino acid transport
BKD09_RS29845	COG1126	abc transporter atp-binding protein
BKD09_RS29855	COG0698	ribose 5-phosphate isomerase
BKD09_RS29870	COG1879	ABC-type sugar transport system periplasmic component
BKD09_RS29880	COG1286	toxin biosynthetic process
BKD09_RS29885	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BKD09_RS29890	COG0300	oxidoreductase activity
BKD09_RS29910	COG1160	GTP binding
BKD09_RS29925	COG0318	PFAM AMP-dependent synthetase and ligase
BKD09_RS29950	COG0306	phosphate transporter
BKD09_RS29955	COG1392	Phosphate transport regulator
BKD09_RS29965	COG0559	Belongs to the binding-protein-dependent transport system permease family
BKD09_RS29990	COG1393	Belongs to the ArsC family
BKD09_RS29995	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKD09_RS29995	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKD09_RS30000	COG1309	transcriptional regulator
BKD09_RS30010	COG0625	glutathione transferase activity
BKD09_RS30055	COG0583	DNA-binding transcription factor activity
BKD09_RS30070	COG1695	Transcriptional regulator
BKD09_RS30085	COG1846	Transcriptional regulator
BKD09_RS30090	COG1764	response to oxidative stress
BKD09_RS30125	COG0242	peptide deformylase activity
BKD09_RS30145	COG3119	arylsulfatase activity
BKD09_RS30180	COG0640	Transcriptional regulator
BKD09_RS30220	COG2207	Transcriptional regulator
BKD09_RS30250	COG0583	DNA-binding transcription factor activity
BKD09_RS30255	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS30275	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BKD09_RS30275	COG0519	Catalyzes the synthesis of GMP from XMP
BKD09_RS30290	COG1278	Cold shock
BKD09_RS30320	COG0765	amino acid transport
BKD09_RS30325	COG0765	amino acid transport
BKD09_RS30340	COG0251	oxidation-reduction process
BKD09_RS30345	COG3608	succinylglutamate desuccinylase aspartoacylase
BKD09_RS30350	COG1609	Transcriptional regulator
BKD09_RS30360	COG2130	NADP-dependent
BKD09_RS30390	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BKD09_RS30415	COG1671	Belongs to the UPF0178 family
BKD09_RS30420	COG0488	(ABC) transporter
BKD09_RS30430	COG0583	DNA-binding transcription factor activity
BKD09_RS30435	COG2814	Major facilitator Superfamily
BKD09_RS30440	COG0493	'glutamate synthase
BKD09_RS30440	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BKD09_RS30445	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS30470	COG1960	acyl-CoA dehydrogenase activity
BKD09_RS30495	COG1024	Enoyl-CoA hydratase
BKD09_RS30500	COG0183	Belongs to the thiolase family
BKD09_RS30505	COG2271	Major facilitator Superfamily
BKD09_RS30520	COG4689	acetoacetate decarboxylase
BKD09_RS30565	COG0765	amino acid transport
BKD09_RS30570	COG0765	amino acid transport
BKD09_RS30575	COG1126	abc transporter atp-binding protein
BKD09_RS30580	COG0277	FAD linked oxidase domain protein
BKD09_RS30585	COG0243	molybdopterin cofactor binding
BKD09_RS30595	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BKD09_RS30605	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BKD09_RS30620	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BKD09_RS30620	COG2066	Belongs to the glutaminase family
BKD09_RS30640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKD09_RS30655	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKD09_RS30660	COG0800	Aldolase
BKD09_RS30665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKD09_RS30670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKD09_RS30675	COG0395	ABC-type sugar transport system, permease component
BKD09_RS30680	COG1175	transmembrane transport
BKD09_RS30690	COG3842	ATPase activity
BKD09_RS30695	COG1609	Transcriptional regulator
BKD09_RS30700	COG0129	dihydroxy-acid dehydratase activity
BKD09_RS30705	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS30710	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS30715	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BKD09_RS30730	COG0583	DNA-binding transcription factor activity
BKD09_RS30735	COG1994	Peptidase M50
BKD09_RS30750	COG0848	biopolymer transport protein
BKD09_RS30760	COG3128	pkhd-type hydroxylase
BKD09_RS30765	COG4774	siderophore transport
BKD09_RS30775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKD09_RS30780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKD09_RS30805	COG1137	ATPase activity
BKD09_RS30830	COG5507	3-demethylubiquinone-9 3-methyltransferase
BKD09_RS30865	COG1454	alcohol dehydrogenase
BKD09_RS30870	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BKD09_RS30875	COG3395	kinase activity
BKD09_RS30880	COG0277	FAD linked oxidase domain protein
BKD09_RS30885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKD09_RS30895	COG1234	tRNA 3'-trailer cleavage
BKD09_RS30905	COG0402	S-adenosylhomocysteine deaminase activity
BKD09_RS30910	COG0477	Major facilitator Superfamily
BKD09_RS30920	COG1802	Transcriptional regulator
BKD09_RS30925	COG1012	belongs to the aldehyde dehydrogenase family
BKD09_RS30930	COG2814	Major facilitator Superfamily
BKD09_RS30945	COG1309	transcriptional regulator
BKD09_RS30950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKD09_RS31020	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BKD09_RS31025	COG2072	flavoprotein involved in K transport
BKD09_RS31030	COG0318	PFAM AMP-dependent synthetase and ligase
BKD09_RS31065	COG1566	PFAM secretion protein HlyD family protein
BKD09_RS31135	COG1116	anion transmembrane transporter activity
BKD09_RS31150	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BKD09_RS31180	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BKD09_RS31240	COG1846	Transcriptional regulator
BKD09_RS31280	COG2080	2 iron, 2 sulfur cluster binding
BKD09_RS31285	COG2010	Cytochrome c
BKD09_RS31285	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BKD09_RS31305	COG1858	cytochrome C peroxidase
BKD09_RS31315	COG1285	pathogenesis
BKD09_RS31345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKD09_RS31350	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BKD09_RS31360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BKD09_RS31365	COG1560	Kdo2-lipid A biosynthetic process
BKD09_RS31380	COG0457	Tetratricopeptide repeat
BKD09_RS31380	COG3710	Transcriptional regulator
BKD09_RS31390	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BKD09_RS31395	COG0436	Aminotransferase
BKD09_RS31405	COG3158	transport of potassium into the cell
BKD09_RS31410	COG3158	transport of potassium into the cell
BKD09_RS31420	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BKD09_RS31445	COG0688	phosphatidylethanolamine metabolic process
BKD09_RS31450	COG5265	(ABC) transporter
BKD09_RS31465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BKD09_RS31475	COG0215	cysteine-tRNA ligase activity
BKD09_RS31495	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BKD09_RS31500	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BKD09_RS31525	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BKD09_RS31530	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BKD09_RS31540	COG0642	Histidine kinase
BKD09_RS31570	COG1012	belongs to the aldehyde dehydrogenase family
BKD09_RS31580	COG2197	response regulator
BKD09_RS31590	COG0431	NADPH-dependent FMN reductase
BKD09_RS31595	COG2267	carboxylic ester hydrolase activity
BKD09_RS31615	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BKD09_RS31645	COG0861	Integral membrane protein TerC family
BKD09_RS31665	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BKD09_RS31665	COG1017	nitric oxide dioxygenase activity
BKD09_RS31695	COG0121	glutamine amidotransferase
BKD09_RS31700	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BKD09_RS31745	COG3546	catalase activity
BKD09_RS31760	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BKD09_RS31765	COG0546	phosphoglycolate phosphatase activity
BKD09_RS31775	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BKD09_RS31780	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BKD09_RS31795	COG5002	protein histidine kinase activity
BKD09_RS31800	COG0745	RESPONSE REGULATOR receiver
BKD09_RS31810	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BKD09_RS31830	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BKD09_RS31835	COG0489	protein tyrosine kinase activity
BKD09_RS31845	COG2084	Dehydrogenase
BKD09_RS31850	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BKD09_RS31855	COG2205	protein histidine kinase activity
BKD09_RS31855	COG2202	Pas domain
BKD09_RS31875	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BKD09_RS31880	COG0598	Magnesium transport protein CorA
BKD09_RS31930	COG2205	protein histidine kinase activity
BKD09_RS31935	COG0745	RESPONSE REGULATOR receiver
BKD09_RS31995	COG0583	DNA-binding transcription factor activity
BKD09_RS32000	COG2814	Major facilitator Superfamily
BKD09_RS32005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKD09_RS32015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKD09_RS32020	COG0601	transmembrane transport
BKD09_RS32025	COG0747	negative chemotaxis
BKD09_RS32030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKD09_RS32035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKD09_RS32040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKD09_RS32045	COG1116	anion transmembrane transporter activity
BKD09_RS32060	COG0426	domain, Protein
BKD09_RS32060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BKD09_RS32065	COG1045	serine acetyltransferase
BKD09_RS32070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKD09_RS32090	COG2072	flavoprotein involved in K transport
BKD09_RS32095	COG2226	methyltransferase
BKD09_RS32100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKD09_RS32105	COG1464	Belongs to the NlpA lipoprotein family
BKD09_RS32115	COG1522	sequence-specific DNA binding
BKD09_RS32130	COG0601	transmembrane transport
BKD09_RS32135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKD09_RS32140	COG4172	Belongs to the ABC transporter superfamily
BKD09_RS32155	COG0583	DNA-binding transcription factor activity
BKD09_RS32170	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKD09_RS32185	COG0477	Major facilitator Superfamily
BKD09_RS32190	COG1024	Enoyl-CoA hydratase
BKD09_RS32215	COG1917	Cupin 2, conserved barrel domain protein
BKD09_RS32215	COG4977	sequence-specific DNA binding
BKD09_RS32240	COG3257	ureidoglycine aminohydrolase activity
BKD09_RS32250	COG1301	dicarboxylic acid transport
BKD09_RS32255	COG0583	DNA-binding transcription factor activity
BKD09_RS32275	COG0251	oxidation-reduction process
BKD09_RS32305	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BKD09_RS32320	COG1764	response to oxidative stress
BKD09_RS32350	COG1672	PFAM Archaeal ATPase
BKD09_RS32350	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BKD09_RS32380	COG2140	Oxalate decarboxylase
BKD09_RS32390	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKD09_RS32400	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BKD09_RS32410	COG0596	Alpha beta hydrolase
BKD09_RS32465	COG0625	glutathione transferase activity
BKD09_RS32480	COG3360	Dodecin
BKD09_RS32500	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKD09_RS32540	COG0318	PFAM AMP-dependent synthetase and ligase
BKD09_RS32550	COG4638	Rieske (2fe-2S)
BKD09_RS32565	COG2207	Transcriptional regulator
BKD09_RS32585	COG4689	acetoacetate decarboxylase
BKD09_RS32605	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS32615	COG0384	phenazine biosynthesis protein PhzF
BKD09_RS32630	COG4191	Histidine kinase
BKD09_RS32635	COG4566	intracellular signal transduction
BKD09_RS32655	COG1566	PFAM secretion protein HlyD family protein
BKD09_RS32660	COG2169	Transcriptional regulator
BKD09_RS32665	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BKD09_RS32675	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
BKD09_RS32695	COG3052	prosthetic group binding
BKD09_RS32730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKD09_RS32740	COG4191	Histidine kinase
BKD09_RS32745	COG0243	molybdopterin cofactor binding
BKD09_RS32750	COG2140	Oxalate decarboxylase
BKD09_RS32755	COG1294	oxidase, subunit
BKD09_RS32760	COG1271	oxidase subunit
BKD09_RS32765	COG0579	oxidoreductase
BKD09_RS32780	COG0114	fumarate hydratase activity
BKD09_RS32790	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BKD09_RS32810	COG3038	cytochrome b561
BKD09_RS32855	COG2207	Transcriptional regulator
BKD09_RS32875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKD09_RS32885	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BKD09_RS32915	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BKD09_RS32920	COG0667	Aldo Keto reductase
BKD09_RS32935	COG2197	response regulator
BKD09_RS32940	COG2197	response regulator
BKD09_RS32955	COG0275	rRNA processing
BKD09_RS32970	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BKD09_RS32975	COG0367	asparagine synthase
BKD09_RS32980	COG0318	PFAM AMP-dependent synthetase and ligase
BKD09_RS32990	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BKD09_RS32995	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BKD09_RS33005	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BKD09_RS33010	COG1596	polysaccharide export
BKD09_RS33030	COG0367	asparagine synthase
BKD09_RS33055	COG2358	TRAP transporter, solute receptor (TAXI family
BKD09_RS33065	COG2890	protein-(glutamine-N5) methyltransferase activity
BKD09_RS33070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKD09_RS33120	COG5441	Belongs to the UPF0261 family
BKD09_RS33125	COG5564	TIM-barrel signal transduction protein
BKD09_RS33130	COG2268	Band 7 protein
BKD09_RS33130	COG2268	Band 7 protein
BKD09_RS33175	COG3618	amidohydrolase
BKD09_RS33185	COG3386	PFAM SMP-30 Gluconolaconase
BKD09_RS33190	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BKD09_RS33195	COG1609	Transcriptional regulator
BKD09_RS33205	COG0673	inositol 2-dehydrogenase activity
BKD09_RS33210	COG0395	ABC-type sugar transport system, permease component
BKD09_RS33215	COG1175	transmembrane transport
BKD09_RS33235	COG0596	Alpha beta hydrolase
BKD09_RS33240	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BKD09_RS33245	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKD09_RS33255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKD09_RS33275	COG1802	Transcriptional regulator
BKD09_RS33280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKD09_RS33285	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKD09_RS33325	COG0683	leucine binding
BKD09_RS33335	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS33340	COG4221	oxidoreductase activity
BKD09_RS33345	COG1802	Transcriptional regulator
BKD09_RS33355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BKD09_RS33370	COG1609	Transcriptional regulator
BKD09_RS33375	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BKD09_RS33380	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BKD09_RS33390	COG1850	ribulose-bisphosphate carboxylase activity
BKD09_RS33400	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BKD09_RS33415	COG0445	tRNA wobble uridine modification
BKD09_RS33435	COG1879	ABC-type sugar transport system periplasmic component
BKD09_RS33440	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKD09_RS33450	COG1070	Carbohydrate kinase
BKD09_RS33455	COG0583	DNA-binding transcription factor activity
BKD09_RS33470	COG0402	S-adenosylhomocysteine deaminase activity
BKD09_RS33480	COG3485	protocatechuate 3,4-dioxygenase
BKD09_RS33485	COG0277	FAD linked oxidase domain protein
BKD09_RS33490	COG1129	ABC transporter
BKD09_RS33495	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKD09_RS33500	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKD09_RS33505	COG1879	ABC-type sugar transport system periplasmic component
BKD09_RS33515	COG4608	Belongs to the ABC transporter superfamily
BKD09_RS33520	COG0444	Belongs to the ABC transporter superfamily
BKD09_RS33525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKD09_RS33530	COG0601	transmembrane transport
BKD09_RS33535	COG0747	negative chemotaxis
BKD09_RS33545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKD09_RS33550	COG0601	transmembrane transport
BKD09_RS33555	COG0747	negative chemotaxis
BKD09_RS33560	COG2072	flavoprotein involved in K transport
BKD09_RS33565	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS33570	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BKD09_RS33585	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BKD09_RS33595	COG0318	PFAM AMP-dependent synthetase and ligase
BKD09_RS33600	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BKD09_RS33640	COG4774	siderophore transport
BKD09_RS33650	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BKD09_RS33665	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BKD09_RS33665	COG1648	precorrin-2 dehydrogenase activity
BKD09_RS33670	COG1797	cobyrinic acid a,c-diamide synthase activity
BKD09_RS33675	COG2875	Belongs to the precorrin methyltransferase family
BKD09_RS33690	COG2099	Precorrin-6x reductase
BKD09_RS33735	COG1492	cobalamin metabolic process
BKD09_RS33745	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BKD09_RS33755	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BKD09_RS33760	COG0778	Nitroreductase
BKD09_RS33795	COG0583	DNA-binding transcription factor activity
BKD09_RS33800	COG0346	lactoylglutathione lyase activity
BKD09_RS33805	COG0400	carboxylic ester hydrolase activity
BKD09_RS33840	COG0583	DNA-binding transcription factor activity
BKD09_RS33845	COG0154	amidase activity
BKD09_RS33850	COG0747	negative chemotaxis
BKD09_RS33860	COG0444	Belongs to the ABC transporter superfamily
BKD09_RS33865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKD09_RS33875	COG0154	amidase activity
BKD09_RS33895	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS33920	COG2390	Transcriptional regulator
BKD09_RS33925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKD09_RS33935	COG0714	Associated with various cellular activities
BKD09_RS33940	COG3256	nitric oxide reductase
BKD09_RS33955	COG1845	cytochrome c oxidase, subunit III
BKD09_RS33960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKD09_RS33960	COG4191	Histidine kinase
BKD09_RS33970	COG4214	carbohydrate transport
BKD09_RS33980	COG4213	ABC transporter substrate-binding protein
BKD09_RS33985	COG3386	PFAM SMP-30 Gluconolaconase
BKD09_RS34005	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKD09_RS34010	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKD09_RS34015	COG1129	ABC transporter
BKD09_RS34020	COG1879	ABC-type sugar transport system periplasmic component
BKD09_RS34040	COG1053	succinate dehydrogenase
BKD09_RS34055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKD09_RS34060	COG4521	taurine ABC transporter
BKD09_RS34065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKD09_RS34070	COG1116	anion transmembrane transporter activity
BKD09_RS34075	COG2855	membrane
BKD09_RS34115	COG1309	transcriptional regulator
BKD09_RS34120	COG2072	flavoprotein involved in K transport
BKD09_RS34130	COG0686	Belongs to the AlaDH PNT family
BKD09_RS34135	COG1522	sequence-specific DNA binding
BKD09_RS34140	COG2080	2 iron, 2 sulfur cluster binding
BKD09_RS34145	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BKD09_RS34150	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BKD09_RS34155	COG1982	Orn Lys Arg decarboxylase major
BKD09_RS34160	COG1247	-acetyltransferase
BKD09_RS34175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKD09_RS34185	COG0028	Belongs to the TPP enzyme family
BKD09_RS34185	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
BKD09_RS34200	COG2084	Dehydrogenase
BKD09_RS34205	COG3622	Belongs to the hyi family
BKD09_RS34210	COG3960	tartronate-semialdehyde synthase activity
BKD09_RS34215	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BKD09_RS34250	COG1802	Transcriptional regulator
BKD09_RS34260	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKD09_RS34285	COG1278	Cold shock
BKD09_RS34295	COG3655	Transcriptional regulator
BKD09_RS34315	COG0443	Heat shock 70 kDa protein
BKD09_RS34335	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BKD09_RS34340	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKD09_RS34370	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS34370	COG0604	alcohol dehydrogenase
BKD09_RS34370	COG3321	synthase
BKD09_RS34375	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BKD09_RS34380	COG2205	protein histidine kinase activity
BKD09_RS34380	COG2202	Pas domain
BKD09_RS34385	COG0583	DNA-binding transcription factor activity
BKD09_RS34400	COG3383	formate dehydrogenase (NAD+) activity
BKD09_RS34405	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BKD09_RS34415	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BKD09_RS34425	COG0489	protein tyrosine kinase activity
BKD09_RS34425	COG3206	protein involved in exopolysaccharide biosynthesis
BKD09_RS34435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKD09_RS34445	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BKD09_RS34450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BKD09_RS34475	COG0811	peptide transport
BKD09_RS34480	COG2831	hemolysin activation secretion protein
BKD09_RS34535	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BKD09_RS34550	COG2192	nodulation
BKD09_RS34565	COG0367	asparagine synthase
BKD09_RS34575	COG0297	glycogen (starch) synthase activity
BKD09_RS34625	COG4969	Belongs to the N-Me-Phe pilin family
BKD09_RS34635	COG1459	type II secretion system
BKD09_RS34640	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BKD09_RS34650	COG1450	Type ii and iii secretion system protein
BKD09_RS34695	COG0745	RESPONSE REGULATOR receiver
BKD09_RS34710	COG3088	subunit of a heme lyase
BKD09_RS34715	COG1138	Cytochrome C-type biogenesis protein
BKD09_RS34720	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BKD09_RS34725	COG4235	cytochrome complex assembly
BKD09_RS34755	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BKD09_RS34780	COG0028	Belongs to the TPP enzyme family
BKD09_RS34795	COG0477	Major facilitator Superfamily
BKD09_RS34800	COG2983	Belongs to the UPF0260 family
BKD09_RS34825	COG0583	DNA-binding transcription factor activity
BKD09_RS34880	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BKD09_RS34885	COG1393	Belongs to the ArsC family
BKD09_RS34890	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKD09_RS34910	COG4774	siderophore transport
BKD09_RS34930	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BKD09_RS34935	COG3958	Transketolase
BKD09_RS34940	COG3959	Transketolase, thiamine diphosphate binding domain
BKD09_RS34945	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS34950	COG0583	DNA-binding transcription factor activity
BKD09_RS34990	COG2205	protein histidine kinase activity
BKD09_RS35000	COG2166	iron-sulfur cluster assembly
BKD09_RS35005	COG4957	zinc ion binding
BKD09_RS35035	COG0433	COG0433 Predicted ATPase
BKD09_RS35050	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BKD09_RS35060	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BKD09_RS35105	COG1703	isobutyryl-CoA mutase activity
BKD09_RS35165	COG1024	Enoyl-CoA hydratase
BKD09_RS35175	COG0563	adenylate kinase activity
BKD09_RS35195	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKD09_RS35205	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS35215	COG0587	DNA-directed DNA polymerase activity
BKD09_RS35235	COG1573	uracil-dna glycosylase
BKD09_RS35240	COG0306	phosphate transporter
BKD09_RS35245	COG1473	amidohydrolase
BKD09_RS35270	COG1595	DNA-templated transcription, initiation
BKD09_RS35295	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BKD09_RS35315	COG1657	PFAM Prenyltransferase squalene oxidase
BKD09_RS35320	COG1233	COG1233 Phytoene dehydrogenase and related
BKD09_RS35325	COG1562	ergosterol biosynthetic process
BKD09_RS35330	COG1562	ergosterol biosynthetic process
BKD09_RS35355	COG4302	ethanolamine ammonia-lyase activity
BKD09_RS35365	COG4303	Ethanolamine ammonia lyase large subunit
BKD09_RS35415	COG0302	gtp cyclohydrolase
BKD09_RS35450	COG2721	sulfolactate sulfo-lyase activity
BKD09_RS35460	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BKD09_RS35475	COG0559	Belongs to the binding-protein-dependent transport system permease family
BKD09_RS35485	COG1846	Transcriptional regulator
BKD09_RS35490	COG3971	2-oxopent-4-enoate hydratase activity
BKD09_RS35500	COG1012	belongs to the aldehyde dehydrogenase family
BKD09_RS35515	COG0028	Belongs to the TPP enzyme family
BKD09_RS35520	COG3145	DNA-N1-methyladenine dioxygenase activity
BKD09_RS35550	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS35555	COG3386	PFAM SMP-30 Gluconolaconase
BKD09_RS35560	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BKD09_RS35575	COG1024	Enoyl-CoA hydratase
BKD09_RS35585	COG1024	Enoyl-CoA hydratase
BKD09_RS35600	COG1960	acyl-CoA dehydrogenase activity
BKD09_RS35605	COG1024	Enoyl-CoA hydratase
BKD09_RS35620	COG1024	Enoyl-CoA hydratase
BKD09_RS35625	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS35640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BKD09_RS35645	COG0625	glutathione transferase activity
BKD09_RS35650	COG2072	flavoprotein involved in K transport
BKD09_RS35655	COG2070	2-Nitropropane dioxygenase
BKD09_RS35675	COG0840	transmembrane signaling receptor activity
BKD09_RS35680	COG3395	kinase activity
BKD09_RS35685	COG3622	Belongs to the hyi family
BKD09_RS35690	COG2084	Dehydrogenase
BKD09_RS35695	COG0235	Class ii aldolase
BKD09_RS35715	COG0559	Belongs to the binding-protein-dependent transport system permease family
BKD09_RS35725	COG4336	lyase activity
BKD09_RS35730	COG0583	DNA-binding transcription factor activity
BKD09_RS35740	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKD09_RS35745	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BKD09_RS35760	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS35775	COG0765	amino acid transport
BKD09_RS35780	COG4597	amino acid ABC transporter
BKD09_RS35790	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BKD09_RS35795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKD09_RS35805	COG1309	transcriptional regulator
BKD09_RS35910	COG1053	succinate dehydrogenase
BKD09_RS35925	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BKD09_RS35930	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BKD09_RS35935	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BKD09_RS35940	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BKD09_RS35975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKD09_RS35990	COG1032	radical SAM domain protein
BKD09_RS36000	COG1966	Carbon starvation protein
BKD09_RS36105	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BKD09_RS36110	COG0784	Response regulator, receiver
BKD09_RS36110	COG4191	Histidine kinase
BKD09_RS36160	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BKD09_RS36245	COG2261	transglycosylase associated protein
BKD09_RS36280	COG3685	Protein conserved in bacteria
BKD09_RS36305	COG0671	phosphoesterase, PA-phosphatase related
BKD09_RS36315	COG0596	Alpha beta hydrolase
BKD09_RS36360	COG0477	Major facilitator Superfamily
BKD09_RS36365	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BKD09_RS36400	COG2050	protein possibly involved in aromatic compounds catabolism
BKD09_RS36405	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BKD09_RS36410	COG2151	metal-sulfur cluster biosynthetic enzyme
BKD09_RS36415	COG3396	Phenylacetate-CoA oxygenase
BKD09_RS36420	COG3460	Phenylacetate-CoA oxygenase
BKD09_RS36425	COG3396	Phenylacetate-CoA oxygenase
BKD09_RS36430	COG3327	negative regulation of DNA-templated transcription, initiation
BKD09_RS36435	COG0596	Alpha beta hydrolase
BKD09_RS36440	COG2733	membrane
BKD09_RS36450	COG0456	acetyltransferase
BKD09_RS36450	COG0454	-acetyltransferase
BKD09_RS36480	COG2124	cytochrome p450
BKD09_RS36480	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BKD09_RS36485	COG2267	carboxylic ester hydrolase activity
BKD09_RS36510	COG0747	negative chemotaxis
BKD09_RS36520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKD09_RS36525	COG0444	Belongs to the ABC transporter superfamily
BKD09_RS36530	COG4608	Belongs to the ABC transporter superfamily
BKD09_RS36545	COG0444	Belongs to the ABC transporter superfamily
BKD09_RS36550	COG4608	Belongs to the ABC transporter superfamily
BKD09_RS36560	COG0601	transmembrane transport
BKD09_RS36565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKD09_RS36580	COG2204	response regulator
BKD09_RS36590	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKD09_RS36595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKD09_RS36605	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
BKD09_RS36605	COG0028	Belongs to the TPP enzyme family
BKD09_RS36615	COG2124	cytochrome p450
BKD09_RS36620	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BKD09_RS36645	COG0673	inositol 2-dehydrogenase activity
BKD09_RS36665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKD09_RS36670	COG1309	transcriptional regulator
BKD09_RS36680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKD09_RS36685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKD09_RS36720	COG0129	dihydroxy-acid dehydratase activity
BKD09_RS36730	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BKD09_RS36760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKD09_RS36775	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BKD09_RS36780	COG1522	sequence-specific DNA binding
BKD09_RS36795	COG1063	alcohol dehydrogenase
BKD09_RS36800	COG0697	spore germination
BKD09_RS36805	COG0656	L-ascorbic acid biosynthetic process
BKD09_RS36815	COG0243	molybdopterin cofactor binding
BKD09_RS36820	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BKD09_RS36825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BKD09_RS36825	COG1017	nitric oxide dioxygenase activity
BKD09_RS36830	COG2223	nitrite transmembrane transporter activity
BKD09_RS36835	COG1116	anion transmembrane transporter activity
BKD09_RS36840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKD09_RS36845	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKD09_RS36860	COG2815	serine threonine protein kinase
BKD09_RS36860	COG0515	serine threonine protein kinase
BKD09_RS36875	COG1672	PFAM Archaeal ATPase
BKD09_RS36875	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BKD09_RS36880	COG3485	protocatechuate 3,4-dioxygenase
BKD09_RS36895	COG4948	Mandelate Racemase Muconate Lactonizing
BKD09_RS36915	COG0642	Histidine kinase
BKD09_RS36920	COG0785	Cytochrome C biogenesis protein
BKD09_RS36935	COG1396	sequence-specific DNA binding
BKD09_RS36945	COG1024	Enoyl-CoA hydratase
BKD09_RS36955	COG0473	3-isopropylmalate dehydrogenase activity
BKD09_RS36970	COG0444	Belongs to the ABC transporter superfamily
BKD09_RS36975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKD09_RS36995	COG0297	glycogen (starch) synthase activity
BKD09_RS37015	COG2217	Heavy metal translocating P-type atpase
BKD09_RS37030	COG2010	Cytochrome c
BKD09_RS37045	COG3278	Belongs to the heme-copper respiratory oxidase family
BKD09_RS37050	COG0517	IMP dehydrogenase activity
BKD09_RS37050	COG0516	GMP reductase activity
BKD09_RS37060	COG4191	Histidine kinase
BKD09_RS37065	COG4566	intracellular signal transduction
BKD09_RS37070	COG4566	intracellular signal transduction
BKD09_RS37075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKD09_RS37095	COG1132	(ABC) transporter
BKD09_RS37100	COG0438	transferase activity, transferring glycosyl groups
BKD09_RS37105	COG2015	COG2015, Alkyl sulfatase and related hydrolases
BKD09_RS37110	COG3706	GGDEF domain
BKD09_RS37125	COG4106	trans-aconitate 2-methyltransferase activity
BKD09_RS37155	COG0387	Pfam Sodium calcium exchanger
BKD09_RS37160	COG0473	3-isopropylmalate dehydrogenase activity
BKD09_RS37165	COG2814	Major facilitator Superfamily
BKD09_RS37170	COG1032	radical SAM domain protein
BKD09_RS37190	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BKD09_RS37215	COG0446	pyridine nucleotide-disulphide oxidoreductase
BKD09_RS37240	COG1653	transport
BKD09_RS37245	COG1175	transmembrane transport
BKD09_RS37265	COG1335	isochorismatase
BKD09_RS37280	COG1053	succinate dehydrogenase
BKD09_RS37285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKD09_RS37305	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BKD09_RS37315	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BKD09_RS37325	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS37335	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS37385	COG1566	PFAM secretion protein HlyD family protein
BKD09_RS37420	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BKD09_RS37435	COG4948	Mandelate Racemase Muconate Lactonizing
BKD09_RS37440	COG1473	amidohydrolase
BKD09_RS37455	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS37460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKD09_RS37475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKD09_RS37495	COG1858	cytochrome C peroxidase
BKD09_RS37520	COG2814	Major facilitator Superfamily
BKD09_RS37560	COG0459	protein refolding
BKD09_RS37565	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BKD09_RS37580	COG1960	acyl-CoA dehydrogenase activity
BKD09_RS37595	COG0737	Belongs to the 5'-nucleotidase family
BKD09_RS37595	COG1525	nuclease
BKD09_RS37595	COG4085	toxin activity
BKD09_RS37600	COG0123	including yeast histone deacetylase and acetoin utilization protein
BKD09_RS37605	COG1722	exodeoxyribonuclease VII activity
BKD09_RS37610	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BKD09_RS37620	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BKD09_RS37625	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BKD09_RS37630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKD09_RS37645	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKD09_RS37675	COG1024	Enoyl-CoA hydratase
BKD09_RS37690	COG0477	Major facilitator Superfamily
BKD09_RS37695	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BKD09_RS37700	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BKD09_RS37705	COG1993	acr, cog1993
BKD09_RS37710	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BKD09_RS37720	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BKD09_RS37730	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BKD09_RS37755	COG0259	pyridoxamine-phosphate oxidase activity
BKD09_RS37760	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS37790	COG0318	PFAM AMP-dependent synthetase and ligase
BKD09_RS37805	COG1960	acyl-CoA dehydrogenase activity
BKD09_RS37825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKD09_RS37845	COG0656	L-ascorbic acid biosynthetic process
BKD09_RS37980	COG4451	ribulose bisphosphate carboxylase, small
BKD09_RS37985	COG1850	ribulose-bisphosphate carboxylase activity
BKD09_RS38005	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BKD09_RS38030	COG2814	Major facilitator Superfamily
BKD09_RS38035	COG1309	transcriptional regulator
BKD09_RS38080	COG0009	L-threonylcarbamoyladenylate synthase
BKD09_RS38085	COG0277	FAD linked oxidase domain protein
BKD09_RS38095	COG0494	nUDIX hydrolase
BKD09_RS38110	COG2135	peptidase activity
BKD09_RS38120	COG1051	belongs to the nudix hydrolase family
BKD09_RS38145	COG1595	DNA-templated transcription, initiation
BKD09_RS38150	COG2897	thiosulfate sulfurtransferase activity
BKD09_RS38155	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BKD09_RS38160	COG0354	folic acid binding
BKD09_RS38165	COG0519	Catalyzes the synthesis of GMP from XMP
BKD09_RS38170	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BKD09_RS38195	COG0840	transmembrane signaling receptor activity
BKD09_RS38200	COG0840	transmembrane signaling receptor activity
BKD09_RS38220	COG0604	alcohol dehydrogenase
BKD09_RS38230	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BKD09_RS38235	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BKD09_RS38250	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BKD09_RS38250	COG0574	Belongs to the PEP-utilizing enzyme family
BKD09_RS38260	COG0751	glycine-tRNA ligase activity
BKD09_RS38265	COG0752	glycyl-tRNA synthetase alpha subunit
BKD09_RS38290	COG0142	geranyltranstransferase activity
BKD09_RS38300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BKD09_RS38305	COG1280	lysine exporter protein (LysE YggA)
BKD09_RS38320	COG2267	carboxylic ester hydrolase activity
BKD09_RS38325	COG0583	DNA-binding transcription factor activity
BKD09_RS38335	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BKD09_RS38350	COG1573	uracil-dna glycosylase
BKD09_RS38360	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BKD09_RS38375	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
BKD09_RS38400	COG0456	acetyltransferase
BKD09_RS38400	COG1846	Transcriptional regulator
BKD09_RS38405	COG0521	Mo-molybdopterin cofactor biosynthetic process
BKD09_RS38410	COG2321	neutral zinc metallopeptidase
BKD09_RS38415	COG2189	Belongs to the N(4) N(6)-methyltransferase family
BKD09_RS38435	COG0625	glutathione transferase activity
BKD09_RS38440	COG0840	transmembrane signaling receptor activity
BKD09_RS38445	COG0840	transmembrane signaling receptor activity
BKD09_RS38450	COG4251	negative regulation of phosphorylation
BKD09_RS38470	COG0625	glutathione transferase activity
BKD09_RS38490	COG1194	a g-specific adenine glycosylase
BKD09_RS38500	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BKD09_RS38500	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BKD09_RS38505	COG1196	nuclear chromosome segregation
BKD09_RS38515	COG1704	LemA family
BKD09_RS38540	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BKD09_RS38555	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BKD09_RS38555	COG2857	Cytochrome c1
BKD09_RS38560	COG0723	plastoquinol--plastocyanin reductase activity
BKD09_RS38565	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BKD09_RS38570	COG0602	queuosine metabolic process
BKD09_RS38580	COG0408	coproporphyrinogen oxidase activity
BKD09_RS38595	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BKD09_RS38610	COG0583	DNA-binding transcription factor activity
BKD09_RS38625	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS38625	COG0604	alcohol dehydrogenase
BKD09_RS38625	COG3321	synthase
BKD09_RS38650	COG0617	tRNA 3'-terminal CCA addition
BKD09_RS38670	COG0714	Associated with various cellular activities
BKD09_RS38695	COG4771	TonB-dependent receptor
BKD09_RS38705	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BKD09_RS38715	COG0463	Glycosyl transferase, family 2
BKD09_RS38730	COG0494	nUDIX hydrolase
BKD09_RS38780	COG0501	Belongs to the peptidase M48B family
BKD09_RS38795	COG1902	pentaerythritol trinitrate reductase activity
BKD09_RS38810	COG0395	ABC-type sugar transport system, permease component
BKD09_RS38820	COG3842	ATPase activity
BKD09_RS38825	COG3842	ATPase activity
BKD09_RS38845	COG1349	DNA-binding transcription factor activity
BKD09_RS38890	COG0183	Belongs to the thiolase family
BKD09_RS38905	COG1309	transcriptional regulator
BKD09_RS38925	COG2337	Toxic component of a toxin-antitoxin (TA) module
BKD09_RS38940	COG3214	Protein conserved in bacteria
BKD09_RS38990	COG3237	CsbD-like
BKD09_RS39000	COG0405	Gamma-glutamyltransferase
BKD09_RS39005	COG1054	Belongs to the UPF0176 family
BKD09_RS39010	COG2900	Belongs to the SlyX family
BKD09_RS39015	COG4251	negative regulation of phosphorylation
BKD09_RS39015	COG3706	GGDEF domain
BKD09_RS39015	COG5001	Diguanylate cyclase
BKD09_RS39015	COG2203	Gaf domain
BKD09_RS39025	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BKD09_RS39030	COG0181	hydroxymethylbilane synthase activity
BKD09_RS39050	COG5001	Diguanylate cyclase
BKD09_RS39050	COG3300	MHYT domain
BKD09_RS39060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BKD09_RS39105	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BKD09_RS39110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKD09_RS39160	COG0438	transferase activity, transferring glycosyl groups
BKD09_RS39180	COG2244	polysaccharide biosynthetic process
BKD09_RS39185	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BKD09_RS39195	COG2755	lipolytic protein G-D-S-L family
BKD09_RS39195	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BKD09_RS39220	COG3206	protein involved in exopolysaccharide biosynthesis
BKD09_RS39220	COG0489	protein tyrosine kinase activity
BKD09_RS39230	COG2755	lipolytic protein G-D-S-L family
BKD09_RS39230	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BKD09_RS39240	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BKD09_RS39250	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BKD09_RS39305	COG2201	protein-glutamate methylesterase activity
BKD09_RS39315	COG0840	transmembrane signaling receptor activity
BKD09_RS39320	COG0835	chemotaxis
BKD09_RS39325	COG0840	transmembrane signaling receptor activity
BKD09_RS39330	COG0835	chemotaxis
BKD09_RS39335	COG0643	Histidine kinase
BKD09_RS39335	COG2198	Histidine kinase
BKD09_RS39340	COG0745	RESPONSE REGULATOR receiver
BKD09_RS39385	COG3485	protocatechuate 3,4-dioxygenase
BKD09_RS39390	COG3485	protocatechuate 3,4-dioxygenase
BKD09_RS39400	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BKD09_RS39405	COG3447	MASE1 domain protein
BKD09_RS39405	COG5002	protein histidine kinase activity
BKD09_RS39405	COG5001	Diguanylate cyclase
BKD09_RS39435	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BKD09_RS39450	COG0431	NADPH-dependent FMN reductase
BKD09_RS39450	COG3976	FMN-binding domain protein
BKD09_RS39450	COG1053	succinate dehydrogenase
BKD09_RS39460	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BKD09_RS39465	COG3383	formate dehydrogenase (NAD+) activity
BKD09_RS39480	COG2223	nitrite transmembrane transporter activity
BKD09_RS39495	COG1763	Mo-molybdopterin cofactor biosynthetic process
BKD09_RS39505	COG0746	molybdenum cofactor guanylyltransferase activity
BKD09_RS39510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKD09_RS39515	COG0303	'Molybdopterin
BKD09_RS39570	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BKD09_RS39570	COG1672	PFAM Archaeal ATPase
BKD09_RS39585	COG0142	geranyltranstransferase activity
BKD09_RS39625	COG3268	Saccharopine dehydrogenase
BKD09_RS39670	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKD09_RS39670	COG1116	anion transmembrane transporter activity
BKD09_RS39695	COG1980	fructose-bisphosphate aldolase activity
BKD09_RS39705	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BKD09_RS39710	COG1278	Cold shock
BKD09_RS39720	COG1615	UPF0182 protein
BKD09_RS39730	COG0437	4 iron, 4 sulfur cluster binding
BKD09_RS39815	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BKD09_RS39845	COG1672	PFAM Archaeal ATPase
BKD09_RS39845	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BKD09_RS39880	COG1595	DNA-templated transcription, initiation
BKD09_RS39890	COG0477	Major facilitator Superfamily
BKD09_RS39895	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS39905	COG1309	transcriptional regulator
BKD09_RS39915	COG0673	inositol 2-dehydrogenase activity
BKD09_RS39920	COG0765	amino acid transport
BKD09_RS39995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKD09_RS40040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKD09_RS40045	COG0683	leucine binding
BKD09_RS40055	COG0411	ABC transporter
BKD09_RS40075	COG4948	Mandelate Racemase Muconate Lactonizing
BKD09_RS40080	COG3684	Belongs to the aldolase LacD family
BKD09_RS40085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKD09_RS40090	COG3842	ATPase activity
BKD09_RS40095	COG1063	alcohol dehydrogenase
BKD09_RS40110	COG1653	transport
BKD09_RS40120	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS40140	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BKD09_RS40160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKD09_RS40170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKD09_RS40180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKD09_RS40210	COG1024	Enoyl-CoA hydratase
BKD09_RS40215	COG0405	Gamma-glutamyltransferase
BKD09_RS40220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKD09_RS40225	COG1126	abc transporter atp-binding protein
BKD09_RS40230	COG0765	amino acid transport
BKD09_RS40235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKD09_RS40245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKD09_RS40250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BKD09_RS40260	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BKD09_RS40265	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BKD09_RS40270	COG2080	2 iron, 2 sulfur cluster binding
BKD09_RS40275	COG1309	transcriptional regulator
BKD09_RS40320	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BKD09_RS40345	COG1595	DNA-templated transcription, initiation
BKD09_RS40365	COG3766	membrane
BKD09_RS40375	COG0754	glutathionylspermidine amidase activity
BKD09_RS40390	COG2201	protein-glutamate methylesterase activity
BKD09_RS40395	COG2198	Histidine kinase
BKD09_RS40395	COG0643	Histidine kinase
BKD09_RS40395	COG0784	Response regulator, receiver
BKD09_RS40400	COG0835	chemotaxis
BKD09_RS40405	COG0643	Histidine kinase
BKD09_RS40405	COG2198	Histidine kinase
BKD09_RS40405	COG0784	Response regulator, receiver
BKD09_RS40415	COG1218	3'(2'),5'-bisphosphate nucleotidase
BKD09_RS40460	COG3920	Histidine kinase
BKD09_RS40470	COG0784	Response regulator, receiver
BKD09_RS40470	COG4191	Histidine kinase
BKD09_RS40475	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
BKD09_RS40480	COG4191	Histidine kinase
BKD09_RS40480	COG0784	Response regulator, receiver
BKD09_RS40495	COG3842	ATPase activity
BKD09_RS40510	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BKD09_RS40515	COG3958	Transketolase
BKD09_RS40520	COG3959	Transketolase, thiamine diphosphate binding domain
BKD09_RS40525	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS40530	COG0583	DNA-binding transcription factor activity
BKD09_RS40550	COG3328	transposase activity
BKD09_RS40615	COG1657	PFAM Prenyltransferase squalene oxidase
BKD09_RS40620	COG0142	geranyltranstransferase activity
BKD09_RS40625	COG2124	cytochrome p450
BKD09_RS40630	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS40640	COG2124	cytochrome p450
BKD09_RS40645	COG2124	cytochrome p450
BKD09_RS40670	COG4974	Belongs to the 'phage' integrase family
BKD09_RS40675	COG0582	viral genome integration into host DNA
BKD09_RS40680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKD09_RS40685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKD09_RS40685	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKD09_RS40760	COG1278	Cold shock
BKD09_RS40780	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BKD09_RS40830	COG0662	Cupin 2, conserved barrel domain protein
BKD09_RS40855	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BKD09_RS40860	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BKD09_RS40870	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BKD09_RS40875	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BKD09_RS40880	COG0156	8-amino-7-oxononanoate synthase activity
BKD09_RS40885	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BKD09_RS40890	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BKD09_RS40905	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BKD09_RS40930	COG0174	glutamine synthetase
BKD09_RS40945	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BKD09_RS41000	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BKD09_RS41025	COG0275	rRNA processing
BKD09_RS41030	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BKD09_RS41035	COG0459	protein refolding
BKD09_RS41060	COG2801	Transposase and inactivated derivatives
BKD09_RS41070	COG3344	reverse transcriptase
BKD09_RS41085	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BKD09_RS41115	COG2086	electron transfer activity
BKD09_RS41120	COG3604	Transcriptional regulator
BKD09_RS41125	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS41140	COG2192	nodulation
BKD09_RS41145	COG2192	nodulation
BKD09_RS41155	COG0842	Transport permease protein
BKD09_RS41160	COG1131	(ABC) transporter
BKD09_RS41165	COG2192	nodulation
BKD09_RS41170	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BKD09_RS41175	COG1215	transferase activity, transferring glycosyl groups
BKD09_RS41185	COG3153	acetyltransferase
BKD09_RS41195	COG0583	DNA-binding transcription factor activity
BKD09_RS41205	COG0583	DNA-binding transcription factor activity
BKD09_RS41215	COG0789	Transcriptional regulator
BKD09_RS41260	COG0730	response to heat
BKD09_RS41265	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BKD09_RS41345	COG3550	peptidyl-serine autophosphorylation
BKD09_RS41485	COG4886	Leucine-rich repeat (LRR) protein
BKD09_RS41565	COG2814	Major facilitator Superfamily
BKD09_RS41575	COG1278	Cold shock
BKD09_RS41580	COG1505	serine-type exopeptidase activity
BKD09_RS41610	COG0583	DNA-binding transcription factor activity
BKD09_RS41660	COG1137	ATPase activity
BKD09_RS41680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKD09_RS41695	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
BKD09_RS41695	COG0028	Belongs to the TPP enzyme family
BKD09_RS41700	COG1012	belongs to the aldehyde dehydrogenase family
BKD09_RS41705	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BKD09_RS41710	COG1278	Cold shock
BKD09_RS41715	COG2771	luxR family
BKD09_RS41740	COG5265	(ABC) transporter
BKD09_RS41770	COG0367	asparagine synthase
BKD09_RS41805	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BKD09_RS41820	COG3012	SEC-C Motif Domain Protein
BKD09_RS41860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKD09_RS41880	COG4372	Transposase
BKD09_RS41885	COG3436	PFAM IS66 Orf2 family protein
BKD09_RS41890	COG2963	transposase activity
BKD09_RS41895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKD09_RS41930	COG3246	L-lysine catabolic process to acetate
BKD09_RS41945	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKD09_RS41975	COG3246	L-lysine catabolic process to acetate
BKD09_RS41990	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS42005	COG1177	transmembrane transport
BKD09_RS42065	COG4372	Transposase
BKD09_RS42070	COG3436	PFAM IS66 Orf2 family protein
BKD09_RS42080	COG2963	transposase activity
BKD09_RS42090	COG2801	Transposase and inactivated derivatives
BKD09_RS42095	COG4608	Belongs to the ABC transporter superfamily
BKD09_RS42105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKD09_RS42125	COG1176	ABC-type spermidine putrescine transport system, permease component I
BKD09_RS42135	COG3842	ATPase activity
BKD09_RS42195	COG0006	proline dipeptidase activity
BKD09_RS42220	COG3842	ATPase activity
BKD09_RS42225	COG1177	transmembrane transport
BKD09_RS42245	COG4584	PFAM Integrase catalytic
BKD09_RS42250	COG1484	DNA-dependent DNA replication
BKD09_RS42255	COG4372	Transposase
BKD09_RS42260	COG3436	PFAM IS66 Orf2 family protein
BKD09_RS42265	COG2963	transposase activity
BKD09_RS42270	COG0006	proline dipeptidase activity
BKD09_RS42280	COG1473	amidohydrolase
BKD09_RS42295	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BKD09_RS42300	COG2086	electron transfer activity
BKD09_RS42305	COG0788	formyltetrahydrofolate deformylase activity
BKD09_RS42315	COG0473	3-isopropylmalate dehydrogenase activity
BKD09_RS42320	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BKD09_RS42335	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BKD09_RS42345	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKD09_RS42355	COG0006	proline dipeptidase activity
BKD09_RS42370	COG3799	methylaspartate ammonia-lyase activity
BKD09_RS42380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BKD09_RS42385	COG1522	sequence-specific DNA binding
BKD09_RS42390	COG2814	Major facilitator Superfamily
BKD09_RS42405	COG0726	polysaccharide deacetylase
BKD09_RS42410	COG1522	sequence-specific DNA binding
BKD09_RS42435	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BKD09_RS42440	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BKD09_RS42445	COG2801	Transposase and inactivated derivatives
BKD09_RS42455	COG1509	lysine 2,3-aminomutase activity
BKD09_RS42505	COG0583	DNA-binding transcription factor activity
BKD09_RS42540	COG0612	Peptidase, M16
BKD09_RS42545	COG0612	Peptidase, M16
BKD09_RS42550	COG5265	(ABC) transporter
BKD09_RS42570	COG0583	DNA-binding transcription factor activity
BKD09_RS42625	COG0222	ribosome binding
BKD09_RS42750	COG2132	Multicopper oxidase
BKD09_RS42775	COG0492	ferredoxin-NADP+ reductase activity
BKD09_RS42825	COG1396	sequence-specific DNA binding
BKD09_RS42840	COG3621	Patatin-like phospholipase
BKD09_RS42915	COG1522	sequence-specific DNA binding
BKD09_RS42920	COG1053	succinate dehydrogenase
BKD09_RS42990	COG3550	peptidyl-serine autophosphorylation
BKD09_RS43045	COG3591	Belongs to the peptidase S1B family
BKD09_RS43090	COG3547	Transposase (IS116 IS110 IS902 family)
BKD09_RS43095	COG2801	Transposase and inactivated derivatives
BKD09_RS43115	COG0436	Aminotransferase
BKD09_RS43155	COG1609	Transcriptional regulator
BKD09_RS43165	COG0477	Major facilitator Superfamily
BKD09_RS43175	COG1024	Enoyl-CoA hydratase
BKD09_RS43230	COG1053	succinate dehydrogenase
BKD09_RS43235	COG5564	TIM-barrel signal transduction protein
BKD09_RS43255	COG2204	response regulator
BKD09_RS43255	COG5564	TIM-barrel signal transduction protein
BKD09_RS43270	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS43275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKD09_RS43280	COG0395	ABC-type sugar transport system, permease component
BKD09_RS43285	COG1175	transmembrane transport
BKD09_RS43320	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BKD09_RS43325	COG2771	luxR family
BKD09_RS43360	COG4584	PFAM Integrase catalytic
BKD09_RS43365	COG1484	DNA-dependent DNA replication
BKD09_RS43425	COG3293	Transposase
BKD09_RS43430	COG2801	Transposase and inactivated derivatives
BKD09_RS43445	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BKD09_RS43480	COG0745	RESPONSE REGULATOR receiver
BKD09_RS43485	COG4964	Belongs to the GSP D family
BKD09_RS43515	COG1484	DNA-dependent DNA replication
BKD09_RS43520	COG4584	PFAM Integrase catalytic
BKD09_RS43560	COG4792	protein secretion
BKD09_RS43565	COG4791	protein targeting
BKD09_RS43570	COG4794	Type iii secretion
BKD09_RS43575	COG4790	Type iii secretion
BKD09_RS43580	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BKD09_RS43590	COG1157	protein secretion by the type III secretion system
BKD09_RS43595	COG1317	bacterial-type flagellum organization
BKD09_RS43605	COG4669	(LipO)protein
BKD09_RS43665	COG4789	Type iii secretion
BKD09_RS43670	COG5010	COG0457 FOG TPR repeat
BKD09_RS43680	COG0612	Peptidase, M16
BKD09_RS43705	COG4886	Leucine-rich repeat (LRR) protein
BKD09_RS43720	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BKD09_RS43735	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKD09_RS43740	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BKD09_RS43745	COG0644	oxidoreductase
BKD09_RS43750	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BKD09_RS43765	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
BKD09_RS43775	COG3047	cAMP biosynthetic process
BKD09_RS43805	COG5554	nitrogen fixation
BKD09_RS43810	COG0535	radical SAM domain protein
BKD09_RS43815	COG5554	nitrogen fixation
BKD09_RS43820	COG1104	cysteine desulfurase activity
BKD09_RS43825	COG0316	Belongs to the HesB IscA family
BKD09_RS43850	COG5420	small protein containing a coiled-coil domain
BKD09_RS43865	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BKD09_RS43870	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BKD09_RS43875	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BKD09_RS43880	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BKD09_RS43900	COG0686	Belongs to the AlaDH PNT family
BKD09_RS43905	COG0309	Hydrogenase expression formation protein (HypE)
BKD09_RS43910	COG0409	Hydrogenase expression formation protein
BKD09_RS43915	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BKD09_RS43915	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BKD09_RS43940	COG0375	protein maturation
BKD09_RS43960	COG0298	carbon dioxide binding
BKD09_RS43970	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
BKD09_RS43975	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
BKD09_RS43980	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
BKD09_RS43995	COG1301	dicarboxylic acid transport
BKD09_RS44015	COG4191	Histidine kinase
BKD09_RS44020	COG4566	intracellular signal transduction
BKD09_RS44025	COG4566	intracellular signal transduction
BKD09_RS44035	COG2390	Transcriptional regulator
BKD09_RS44035	COG4584	PFAM Integrase catalytic
BKD09_RS44040	COG1484	DNA-dependent DNA replication
BKD09_RS44065	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BKD09_RS44120	COG3831	ATPase activity
BKD09_RS44135	COG1484	DNA-dependent DNA replication
BKD09_RS44140	COG4584	PFAM Integrase catalytic
BKD09_RS44205	COG0765	amino acid transport
BKD09_RS44225	COG4886	Leucine-rich repeat (LRR) protein
BKD09_RS44265	COG2801	Transposase and inactivated derivatives
BKD09_RS44295	COG1196	nuclear chromosome segregation
BKD09_RS44340	COG3547	Transposase (IS116 IS110 IS902 family)
BKD09_RS44400	COG4584	PFAM Integrase catalytic
BKD09_RS44405	COG1484	DNA-dependent DNA replication
BKD09_RS44475	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BKD09_RS44485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKD09_RS44490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKD09_RS44560	COG4227	nucleotidyltransferase activity
BKD09_RS44580	COG3547	Transposase (IS116 IS110 IS902 family)
BKD09_RS44620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKD09_RS44630	COG0747	negative chemotaxis
BKD09_RS44640	COG2186	Transcriptional regulator
BKD09_RS44665	COG0071	Belongs to the small heat shock protein (HSP20) family
BKD09_RS44700	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BKD09_RS44725	COG0736	holo-[acyl-carrier-protein] synthase activity
BKD09_RS44830	COG1408	metallophosphoesterase
BKD09_RS44835	COG2255	four-way junction helicase activity
BKD09_RS44845	COG0632	four-way junction helicase activity
BKD09_RS44850	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BKD09_RS44855	COG0217	transcriptional regulatory protein
BKD09_RS44890	COG0523	cobalamin synthesis protein
BKD09_RS44895	COG1692	metallophosphoesterase
BKD09_RS44930	COG0126	phosphoglycerate kinase activity
BKD09_RS44940	COG3588	fructose-bisphosphate aldolase
BKD09_RS44955	COG0483	inositol monophosphate 1-phosphatase activity
BKD09_RS44965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKD09_RS44975	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BKD09_RS45000	COG1132	(ABC) transporter
BKD09_RS45005	COG0254	rRNA binding
BKD09_RS45020	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKD09_RS45045	COG3706	GGDEF domain
BKD09_RS45045	COG5001	Diguanylate cyclase
BKD09_RS45045	COG2203	Gaf domain
BKD09_RS45045	COG4251	negative regulation of phosphorylation
BKD09_RS45050	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BKD09_RS45055	COG2951	lytic endotransglycosylase activity
BKD09_RS45065	COG3237	CsbD-like
BKD09_RS45070	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS45075	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS45085	COG1678	Uncharacterized ACR, COG1678
BKD09_RS45100	COG0730	response to heat
BKD09_RS45105	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS45120	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BKD09_RS45125	COG4208	sulfate ABC transporter
BKD09_RS45130	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BKD09_RS45135	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BKD09_RS45140	COG0175	sulfate reduction
BKD09_RS45150	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BKD09_RS45160	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BKD09_RS45160	COG1648	precorrin-2 dehydrogenase activity
BKD09_RS45165	COG0175	sulfate reduction
BKD09_RS45175	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BKD09_RS45190	COG1376	ErfK ybiS ycfS ynhG family protein
BKD09_RS45190	COG1388	LysM domain
BKD09_RS45195	COG0628	permease
BKD09_RS45225	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BKD09_RS45230	COG0830	nickel cation binding
BKD09_RS45245	COG0804	urea catabolic process
BKD09_RS45250	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BKD09_RS45255	COG0832	Belongs to the urease beta subunit family
BKD09_RS45260	COG0831	urea catabolic process
BKD09_RS45265	COG0829	nickel cation binding
BKD09_RS45295	COG0513	Belongs to the DEAD box helicase family
BKD09_RS45300	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BKD09_RS45305	COG1278	Cold shock
BKD09_RS45335	COG4964	Belongs to the GSP D family
BKD09_RS45380	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BKD09_RS45385	COG0791	NLP P60 protein
BKD09_RS45390	COG4172	Belongs to the ABC transporter superfamily
BKD09_RS45395	COG4239	(ABC) transporter, permease
BKD09_RS45400	COG4174	ABC transporter (Permease)
BKD09_RS45405	COG4166	transmembrane transport
BKD09_RS45410	COG4166	transmembrane transport
BKD09_RS45415	COG3474	cytochrome
BKD09_RS45420	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BKD09_RS45425	COG0077	Prephenate dehydratase
BKD09_RS45425	COG1605	Chorismate mutase
BKD09_RS45430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKD09_RS45480	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BKD09_RS45490	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS45495	COG1960	acyl-CoA dehydrogenase activity
BKD09_RS45500	COG1960	acyl-CoA dehydrogenase activity
BKD09_RS45505	COG0183	Belongs to the thiolase family
BKD09_RS45510	COG0318	PFAM AMP-dependent synthetase and ligase
BKD09_RS45590	COG0583	DNA-binding transcription factor activity
BKD09_RS45615	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BKD09_RS45625	COG1024	Enoyl-CoA hydratase
BKD09_RS45630	COG3320	Male sterility
BKD09_RS45630	COG1022	Amp-dependent synthetase and ligase
BKD09_RS45690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKD09_RS45695	COG1024	Enoyl-CoA hydratase
BKD09_RS45710	COG2378	regulation of single-species biofilm formation
BKD09_RS45725	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BKD09_RS45730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKD09_RS45740	COG0604	alcohol dehydrogenase
BKD09_RS45750	COG2186	Transcriptional regulator
BKD09_RS45760	COG1917	Cupin 2, conserved barrel domain protein
BKD09_RS45760	COG2207	Transcriptional regulator
BKD09_RS45765	COG0318	PFAM AMP-dependent synthetase and ligase
BKD09_RS45770	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKD09_RS45775	COG1879	ABC-type sugar transport system periplasmic component
BKD09_RS45790	COG1129	ABC transporter
BKD09_RS45835	COG0287	Prephenate dehydrogenase
BKD09_RS45835	COG1605	Chorismate mutase
BKD09_RS45840	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BKD09_RS45845	COG0830	nickel cation binding
BKD09_RS45850	COG0804	urea catabolic process
BKD09_RS45855	COG0832	Belongs to the urease beta subunit family
BKD09_RS45865	COG0831	urea catabolic process
BKD09_RS45870	COG0829	nickel cation binding
BKD09_RS45895	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BKD09_RS45900	COG0633	Ferredoxin
BKD09_RS45900	COG0543	2 iron, 2 sulfur cluster binding
BKD09_RS45920	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS45925	COG3321	synthase
BKD09_RS45925	COG4221	oxidoreductase activity
BKD09_RS45925	COG0604	alcohol dehydrogenase
BKD09_RS45925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKD09_RS45930	COG0596	Alpha beta hydrolase
BKD09_RS45940	COG4566	intracellular signal transduction
BKD09_RS45945	COG4191	Histidine kinase
BKD09_RS45960	COG3920	Histidine kinase
BKD09_RS45970	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BKD09_RS45980	COG4566	intracellular signal transduction
BKD09_RS45990	COG4191	Histidine kinase
BKD09_RS46005	COG2169	Transcriptional regulator
BKD09_RS46005	COG1917	Cupin 2, conserved barrel domain protein
BKD09_RS46025	COG1902	pentaerythritol trinitrate reductase activity
BKD09_RS46055	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS46060	COG0640	Transcriptional regulator
BKD09_RS46075	COG1755	Isoprenylcysteine carboxyl methyltransferase
BKD09_RS46100	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS46110	COG1028	Short-chain dehydrogenase reductase Sdr
BKD09_RS46130	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKD09_RS46150	COG2267	carboxylic ester hydrolase activity
BKD09_RS46160	COG0154	amidase activity
BKD09_RS46170	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BKD09_RS46175	COG1960	acyl-CoA dehydrogenase activity
BKD09_RS46180	COG4221	oxidoreductase activity
BKD09_RS46185	COG1024	Enoyl-CoA hydratase
BKD09_RS46200	COG0583	DNA-binding transcription factor activity
BKD09_RS46225	COG1058	Belongs to the CinA family
BKD09_RS46225	COG1546	Belongs to the CinA family
BKD09_RS46250	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BKD09_RS46255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKD09_RS46260	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
BKD09_RS46270	COG0444	Belongs to the ABC transporter superfamily
BKD09_RS46275	COG0154	amidase activity
BKD09_RS46285	COG4608	Belongs to the ABC transporter superfamily
BKD09_RS46290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKD09_RS46300	COG0747	negative chemotaxis
BKD09_RS46305	COG0747	negative chemotaxis
BKD09_RS46330	COG2207	Transcriptional regulator
BKD09_RS46405	COG2309	aminopeptidase activity
BKD09_RS46410	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BKD09_RS46425	COG2020	methyltransferase activity
BKD09_RS46470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKD09_RS46525	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BKD09_RS46530	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BKD09_RS46535	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BKD09_RS46540	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BKD09_RS46550	COG0156	8-amino-7-oxononanoate synthase activity
BKD09_RS46560	COG2198	Histidine kinase
BKD09_RS46560	COG2205	protein histidine kinase activity
BKD09_RS46560	COG0784	Response regulator, receiver
BKD09_RS46575	COG0596	Alpha beta hydrolase
BKD09_RS46580	COG1764	response to oxidative stress
BKD09_RS46600	COG0432	Pfam Uncharacterised protein family UPF0047
BKD09_RS46615	COG0356	it plays a direct role in the translocation of protons across the membrane
BKD09_RS46625	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BKD09_RS46630	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BKD09_RS46640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKD09_RS46645	COG0612	Peptidase, M16
BKD09_RS46670	COG3346	SURF1 family
BKD09_RS46685	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BKD09_RS46695	COG0109	protoheme IX farnesyltransferase activity
BKD09_RS46700	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BKD09_RS46705	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BKD09_RS46715	COG0312	modulator of DNA gyrase
BKD09_RS46720	COG0681	Belongs to the peptidase S26 family
BKD09_RS46735	COG0583	DNA-binding transcription factor activity
BKD09_RS46740	COG0697	spore germination
BKD09_RS46755	COG0730	response to heat
BKD09_RS46770	COG1695	Transcriptional regulator
BKD09_RS46780	COG1960	acyl-CoA dehydrogenase activity
BKD09_RS46785	COG0183	Belongs to the thiolase family
BKD09_RS46790	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKD09_RS46790	COG1024	Enoyl-CoA hydratase
BKD09_RS46805	COG0625	glutathione transferase activity
BKD09_RS46830	COG0058	SHG alpha-glucan phosphorylase activity
BKD09_RS46840	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BKD09_RS46855	COG0745	RESPONSE REGULATOR receiver
BKD09_RS46860	COG2205	protein histidine kinase activity
BKD09_RS46870	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKD09_RS46870	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKD09_RS46885	COG0481	GTPase activity
BKD09_RS46965	COG0745	RESPONSE REGULATOR receiver
BKD09_RS46975	COG1960	acyl-CoA dehydrogenase activity
BKD09_RS46980	COG5001	Diguanylate cyclase
BKD09_RS46985	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
BKD09_RS46995	COG0725	ABC transporter, periplasmic molybdate-binding protein
BKD09_RS47000	COG4149	molybdate abc transporter
BKD09_RS47005	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BKD09_RS47010	COG3263	regulation of cellular component size
BKD09_RS47015	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BKD09_RS47015	COG3264	Mechanosensitive ion channel
BKD09_RS47020	COG0024	Methionine aminopeptidase
BKD09_RS47030	COG1309	transcriptional regulator
BKD09_RS47055	COG2003	Belongs to the UPF0758 family
BKD09_RS47060	COG0582	viral genome integration into host DNA
BKD09_RS47065	COG4804	nuclease activity
BKD09_RS47075	COG0419	ATPase involved in DNA repair
BKD09_RS47115	COG3293	Transposase
BKD09_RS47135	COG1376	ErfK ybiS ycfS ynhG family protein
BKD09_RS47140	COG0300	oxidoreductase activity
BKD09_RS47205	COG0582	viral genome integration into host DNA
BKD09_RS47210	COG4372	Transposase
BKD09_RS47220	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BKD09_RS47285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKD09_RS47315	COG4584	PFAM Integrase catalytic
BKD09_RS47320	COG1484	DNA-dependent DNA replication
BKD09_RS47365	COG1181	Belongs to the D-alanine--D-alanine ligase family
BKD09_RS47375	COG0405	Gamma-glutamyltransferase
BKD09_RS47410	COG2801	Transposase and inactivated derivatives
BKD09_RS47420	COG3436	PFAM IS66 Orf2 family protein
BKD09_RS47440	COG3831	ATPase activity
BKD09_RS47500	COG1278	Cold shock
BKD09_RS47575	COG2801	Transposase and inactivated derivatives
BKD09_RS47645	COG0583	DNA-binding transcription factor activity
BKD09_RS47655	COG0596	Alpha beta hydrolase
BKD09_RS47665	COG2948	multi-organism process
BKD09_RS47675	COG3701	Conjugal transfer protein
BKD09_RS47695	COG3451	type IV secretory pathway VirB4
BKD09_RS47705	COG3838	Conjugal transfer protein Trbc
BKD09_RS47710	COG4962	Type ii secretion system protein e
BKD09_RS47730	COG5265	(ABC) transporter
BKD09_RS47760	COG3547	Transposase (IS116 IS110 IS902 family)
BKD09_RS47795	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BKD09_RS47805	COG0776	regulation of translation
BKD09_RS47815	COG3344	reverse transcriptase
BKD09_RS47820	COG2801	Transposase and inactivated derivatives
BKD09_RS47825	COG4584	PFAM Integrase catalytic
BKD09_RS47850	COG2801	Transposase and inactivated derivatives
BKD09_RS47935	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BKD09_RS47940	COG2003	Belongs to the UPF0758 family
BKD09_RS48010	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BKD09_RS48075	COG1525	nuclease
BKD09_RS48090	COG0156	8-amino-7-oxononanoate synthase activity
BKD09_RS48110	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BKD09_RS48150	COG0681	Belongs to the peptidase S26 family
BKD09_RS48250	COG1793	dna ligase
BKD09_RS48275	COG0656	L-ascorbic acid biosynthetic process
BKD09_RS48295	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BKD09_RS48325	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKD09_RS48350	COG2010	Cytochrome c
BKD09_RS48535	COG0270	DNA (cytosine-5-)-methyltransferase activity
BKD09_RS48620	COG0668	transmembrane transport
BKD09_RS48850	COG2989	Protein conserved in bacteria
BKD09_RS48920	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BKD09_RS49140	COG0683	leucine binding
BKD09_RS49145	COG2771	luxR family
BKD09_RS49225	COG3547	Transposase (IS116 IS110 IS902 family)
BKD09_RS49290	COG3246	L-lysine catabolic process to acetate
BKD09_RS49330	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BKD09_RS49335	COG4372	Transposase
BKD09_RS49350	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BKD09_RS49355	COG2801	Transposase and inactivated derivatives
BKD09_RS49390	COG3436	PFAM IS66 Orf2 family protein
BKD09_RS49405	COG4372	Transposase
BKD09_RS49410	COG4974	Belongs to the 'phage' integrase family
BKD09_RS49535	COG4372	Transposase
BKD09_RS49540	COG3436	PFAM IS66 Orf2 family protein
BKD09_RS49575	COG5461	TIGRFAM pilus (Caulobacter type) biogenesis lipoprotein CpaD
BKD09_RS49630	COG4886	Leucine-rich repeat (LRR) protein
BKD09_RS49655	COG3411	Ferredoxin
BKD09_RS49660	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BKD09_RS49670	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BKD09_RS49685	COG4372	Transposase
BKD09_RS49775	COG3328	transposase activity
BKD09_RS49790	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BKD09_RS49850	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BKD09_RS49925	COG2801	Transposase and inactivated derivatives
BKD09_RS49925	COG3415	Transposase
BKD09_RS49930	COG4372	Transposase
BKD09_RS49980	COG2223	nitrite transmembrane transporter activity
