locus-tag	class	description
XI02_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
XI02_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XI02_RS00025	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XI02_RS00030	COG0534	Mate efflux family protein
XI02_RS00075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XI02_RS00080	COG1741	Belongs to the pirin family
XI02_RS00085	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XI02_RS00090	COG1024	Enoyl-CoA hydratase
XI02_RS00095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XI02_RS00130	COG0318	PFAM AMP-dependent synthetase and ligase
XI02_RS00135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XI02_RS00145	COG0180	Tryptophanyl-tRNA synthetase
XI02_RS00160	COG1214	PFAM Peptidase M22, glycoprotease
XI02_RS00175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XI02_RS00180	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XI02_RS00185	COG1702	phosphate starvation-inducible protein PhoH
XI02_RS00190	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XI02_RS00200	COG0815	Transfers the fatty acyl group on membrane lipoproteins
XI02_RS00205	COG1396	sequence-specific DNA binding
XI02_RS00215	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XI02_RS00230	COG0779	Required for maturation of 30S ribosomal subunits
XI02_RS00245	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XI02_RS00250	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XI02_RS00255	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XI02_RS00260	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XI02_RS00265	COG1185	polyribonucleotide nucleotidyltransferase activity
XI02_RS00280	COG0625	glutathione transferase activity
XI02_RS00295	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XI02_RS00320	COG0667	Aldo Keto reductase
XI02_RS00325	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XI02_RS00345	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XI02_RS00350	COG2226	methyltransferase
XI02_RS00355	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XI02_RS00360	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XI02_RS00370	COG2205	protein histidine kinase activity
XI02_RS00375	COG3178	'Phosphotransferase
XI02_RS00385	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XI02_RS00410	COG1074	ATP-dependent DNA helicase activity
XI02_RS00430	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XI02_RS00435	COG0159	tryptophan synthase activity
XI02_RS00440	COG0133	tryptophan synthase activity
XI02_RS00445	COG0135	phosphoribosylanthranilate isomerase activity
XI02_RS00455	COG0776	regulation of translation
XI02_RS00460	COG0616	signal peptide processing
XI02_RS00465	COG0539	negative regulation of cytoplasmic translation
XI02_RS00470	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XI02_RS00475	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XI02_RS00495	COG1846	Transcriptional regulator
XI02_RS00500	COG1764	response to oxidative stress
XI02_RS00520	COG0395	ABC-type sugar transport system, permease component
XI02_RS00525	COG3842	ATPase activity
XI02_RS00530	COG0071	Belongs to the small heat shock protein (HSP20) family
XI02_RS00550	COG0318	PFAM AMP-dependent synthetase and ligase
XI02_RS00570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XI02_RS00575	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
XI02_RS00580	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
XI02_RS00585	COG1137	ATPase activity
XI02_RS00590	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XI02_RS00600	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XI02_RS00610	COG2814	Major facilitator Superfamily
XI02_RS00625	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XI02_RS00640	COG1968	undecaprenyl-diphosphatase activity
XI02_RS00650	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XI02_RS00670	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XI02_RS00675	COG0291	Belongs to the bacterial ribosomal protein bL35 family
XI02_RS00680	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
XI02_RS00690	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XI02_RS00695	COG2852	Protein conserved in bacteria
XI02_RS00700	COG0072	phenylalanine-tRNA ligase activity
XI02_RS00700	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XI02_RS00730	COG0864	Transcriptional regulator
XI02_RS00735	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XI02_RS00750	COG0477	Major facilitator Superfamily
XI02_RS00765	COG1755	Isoprenylcysteine carboxyl methyltransferase
XI02_RS00785	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XI02_RS00795	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
XI02_RS00800	COG0588	phosphoglycerate mutase activity
XI02_RS00805	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
XI02_RS00815	COG0284	orotidine-5'-phosphate decarboxylase activity
XI02_RS00820	COG0431	NADPH-dependent FMN reductase
XI02_RS00825	COG3963	phosphatidate phosphatase activity
XI02_RS00830	COG0484	heat shock protein binding
XI02_RS00835	COG0443	Heat shock 70 kDa protein
XI02_RS00845	COG1335	isochorismatase
XI02_RS00860	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XI02_RS00865	COG1420	regulation of RNA biosynthetic process
XI02_RS00870	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XI02_RS00875	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
XI02_RS00880	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XI02_RS00890	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
XI02_RS00895	COG0792	nuclease activity
XI02_RS00900	COG0189	ligase activity
XI02_RS00905	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XI02_RS00915	COG4774	siderophore transport
XI02_RS00940	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XI02_RS00945	COG0606	chelatase, subunit chli
XI02_RS00960	COG3547	Transposase (IS116 IS110 IS902 family)
XI02_RS00965	COG1072	(Pantothenic acid kinase))
XI02_RS00970	COG0140	phosphoribosyl-ATP diphosphatase activity
XI02_RS00975	COG0107	imidazoleglycerol-phosphate synthase activity
XI02_RS00980	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XI02_RS00985	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XI02_RS00995	COG0131	Imidazoleglycerol-phosphate dehydratase
XI02_RS01000	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
XI02_RS01015	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
XI02_RS01030	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
XI02_RS01040	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
XI02_RS01050	COG0237	dephospho-CoA kinase activity
XI02_RS01055	COG0424	maF-like protein
XI02_RS01060	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
XI02_RS01065	COG1981	membrane
XI02_RS01070	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XI02_RS01080	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
XI02_RS01085	COG0445	tRNA wobble uridine modification
XI02_RS01090	COG0357	Ribosomal RNA small subunit methyltransferase G
XI02_RS01115	COG0495	leucyl-tRNA aminoacylation
XI02_RS01120	COG3706	GGDEF domain
XI02_RS01125	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XI02_RS01140	COG0745	RESPONSE REGULATOR receiver
XI02_RS01155	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
XI02_RS01160	COG1674	ftsk spoiiie
XI02_RS01165	COG0436	Aminotransferase
XI02_RS01180	COG0004	ammonium transporteR
XI02_RS01185	COG0347	Belongs to the P(II) protein family
XI02_RS01190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XI02_RS01195	COG1960	acyl-CoA dehydrogenase activity
XI02_RS01200	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XI02_RS01220	COG0740	serine-type endopeptidase activity
XI02_RS01230	COG0640	Transcriptional regulator
XI02_RS01235	COG0004	ammonium transporteR
XI02_RS01240	COG0347	Belongs to the P(II) protein family
XI02_RS01250	COG1946	Acyl-CoA thioesterase
XI02_RS01255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XI02_RS01260	COG2835	tetraacyldisaccharide 4'-kinase activity
XI02_RS01285	COG5001	Diguanylate cyclase
XI02_RS01285	COG3300	MHYT domain
XI02_RS01300	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
XI02_RS01305	COG3118	belongs to the thioredoxin family
XI02_RS01340	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XI02_RS01350	COG0534	Mate efflux family protein
XI02_RS01375	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS01380	COG2814	Major facilitator Superfamily
XI02_RS01385	COG0405	Gamma-glutamyltransferase
XI02_RS01395	COG0138	bifunctional purine biosynthesis protein purh
XI02_RS01420	COG1376	ErfK ybiS ycfS ynhG family protein
XI02_RS01425	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XI02_RS01450	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XI02_RS01455	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XI02_RS01495	COG2814	Major facilitator Superfamily
XI02_RS01520	COG4221	oxidoreductase activity
XI02_RS01530	COG1024	Enoyl-CoA hydratase
XI02_RS01545	COG1872	DUF167
XI02_RS01550	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XI02_RS01555	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XI02_RS01560	COG1247	-acetyltransferase
XI02_RS01590	COG1217	gtp-binding protein TYPA
XI02_RS01610	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XI02_RS01635	COG2197	response regulator
XI02_RS01675	COG2154	pterin-4-alpha-carbinolamine dehydratase
XI02_RS01685	COG1063	alcohol dehydrogenase
XI02_RS01690	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS01700	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XI02_RS01710	COG0671	phosphoesterase, PA-phosphatase related
XI02_RS01715	COG0137	argininosuccinate synthase activity
XI02_RS01730	COG1785	Belongs to the alkaline phosphatase family
XI02_RS01750	COG4178	(ABC) transporter
XI02_RS01770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XI02_RS01770	COG1042	CoA-binding domain protein
XI02_RS01770	COG0045	succinate-CoA ligase (ADP-forming) activity
XI02_RS01790	COG2009	succinate dehydrogenase
XI02_RS01800	COG0730	response to heat
XI02_RS01810	COG0318	PFAM AMP-dependent synthetase and ligase
XI02_RS01815	COG4221	oxidoreductase activity
XI02_RS01825	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XI02_RS01830	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
XI02_RS01835	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XI02_RS01840	COG0477	Major facilitator Superfamily
XI02_RS01850	COG0473	3-isopropylmalate dehydrogenase activity
XI02_RS01865	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XI02_RS01870	COG2862	Uncharacterized protein family, UPF0114
XI02_RS01875	COG0288	reversible hydration of carbon dioxide
XI02_RS01880	COG2301	Belongs to the HpcH HpaI aldolase family
XI02_RS01900	COG0066	3-isopropylmalate dehydratase activity
XI02_RS01940	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XI02_RS01945	COG0335	large ribosomal subunit rRNA binding
XI02_RS01950	COG0336	Belongs to the RNA methyltransferase TrmD family
XI02_RS01970	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XI02_RS01975	COG0228	four-way junction DNA binding
XI02_RS01980	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XI02_RS02000	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XI02_RS02005	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XI02_RS02020	COG0564	pseudouridine synthase activity
XI02_RS02025	COG0552	protein localization to endoplasmic reticulum
XI02_RS02030	COG2917	probably involved in intracellular septation
XI02_RS02040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XI02_RS02050	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XI02_RS02055	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XI02_RS02060	COG4133	protoheme IX ABC transporter activity
XI02_RS02065	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
XI02_RS02080	COG0670	Belongs to the BI1 family
XI02_RS02085	COG0577	efflux transmembrane transporter activity
XI02_RS02085	COG1136	(ABC) transporter
XI02_RS02090	COG4181	ATPase activity
XI02_RS02100	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
XI02_RS02105	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XI02_RS02110	COG0039	L-malate dehydrogenase activity
XI02_RS02115	COG0045	succinate-CoA ligase (ADP-forming) activity
XI02_RS02125	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XI02_RS02135	COG0508	dehydrogenase complex catalyzes the overall conversion of
XI02_RS02140	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS02145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XI02_RS02160	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XI02_RS02170	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XI02_RS02175	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XI02_RS02180	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XI02_RS02185	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XI02_RS02190	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XI02_RS02195	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XI02_RS02210	COG0494	nUDIX hydrolase
XI02_RS02215	COG1051	belongs to the nudix hydrolase family
XI02_RS02225	COG0793	Belongs to the peptidase S41A family
XI02_RS02235	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XI02_RS02240	COG0799	negative regulation of ribosome biogenesis
XI02_RS02245	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XI02_RS02250	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XI02_RS02255	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XI02_RS02260	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XI02_RS02275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XI02_RS02280	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XI02_RS02285	COG0261	This protein binds to 23S rRNA in the presence of protein L20
XI02_RS02310	COG0488	(ABC) transporter
XI02_RS02320	COG4993	Dehydrogenase
XI02_RS02335	COG0583	DNA-binding transcription factor activity
XI02_RS02340	COG2814	Major facilitator Superfamily
XI02_RS02345	COG0667	Aldo Keto reductase
XI02_RS02355	COG2072	flavoprotein involved in K transport
XI02_RS02365	COG2205	protein histidine kinase activity
XI02_RS02370	COG0745	RESPONSE REGULATOR receiver
XI02_RS02375	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XI02_RS02385	COG0438	transferase activity, transferring glycosyl groups
XI02_RS02395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XI02_RS02400	COG1472	Belongs to the glycosyl hydrolase 3 family
XI02_RS02435	COG2198	Histidine kinase
XI02_RS02435	COG0643	Histidine kinase
XI02_RS02435	COG0784	Response regulator, receiver
XI02_RS02440	COG0835	chemotaxis
XI02_RS02465	COG4566	intracellular signal transduction
XI02_RS02475	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XI02_RS02485	COG1178	ABC-type Fe3 transport system permease component
XI02_RS02495	COG3842	ATPase activity
XI02_RS02500	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XI02_RS02530	COG0596	Alpha beta hydrolase
XI02_RS02540	COG1278	Cold shock
XI02_RS02565	COG0747	negative chemotaxis
XI02_RS02575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XI02_RS02585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XI02_RS02625	COG2084	Dehydrogenase
XI02_RS02635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XI02_RS02650	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
XI02_RS02655	COG0179	Fumarylacetoacetate (FAA) hydrolase
XI02_RS02660	COG3813	Protein conserved in bacteria
XI02_RS02665	COG1522	sequence-specific DNA binding
XI02_RS02675	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XI02_RS02735	COG0477	Major facilitator Superfamily
XI02_RS02745	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
XI02_RS02790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XI02_RS02810	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XI02_RS02815	COG0297	glycogen (starch) synthase activity
XI02_RS02840	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
XI02_RS02845	COG1596	polysaccharide export
XI02_RS02850	COG0367	asparagine synthase
XI02_RS02855	COG1960	acyl-CoA dehydrogenase activity
XI02_RS02870	COG0736	holo-[acyl-carrier-protein] synthase activity
XI02_RS02885	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XI02_RS02890	COG2197	response regulator
XI02_RS02895	COG2197	response regulator
XI02_RS02920	COG0850	regulation of cytokinetic process
XI02_RS02925	COG2894	cell division
XI02_RS02930	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XI02_RS02940	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XI02_RS02945	COG3474	cytochrome
XI02_RS02955	COG1522	sequence-specific DNA binding
XI02_RS02960	COG2515	1-aminocyclopropane-1-carboxylate deaminase
XI02_RS02975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XI02_RS02980	COG1408	metallophosphoesterase
XI02_RS02985	COG2072	flavoprotein involved in K transport
XI02_RS02990	COG0514	ATP-dependent DNA helicase (RecQ)
XI02_RS02995	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XI02_RS02995	COG2010	Cytochrome c
XI02_RS03000	COG2080	2 iron, 2 sulfur cluster binding
XI02_RS03005	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XI02_RS03005	COG2010	Cytochrome c
XI02_RS03030	COG1011	Hydrolase
XI02_RS03055	COG1404	Belongs to the peptidase S8 family
XI02_RS03065	COG2197	response regulator
XI02_RS03130	COG3246	L-lysine catabolic process to acetate
XI02_RS03135	COG0318	PFAM AMP-dependent synthetase and ligase
XI02_RS03140	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XI02_RS03150	COG4608	Belongs to the ABC transporter superfamily
XI02_RS03155	COG0444	Belongs to the ABC transporter superfamily
XI02_RS03160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XI02_RS03165	COG0601	transmembrane transport
XI02_RS03230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XI02_RS03245	COG3788	relative of glutathione S-transferase, MAPEG superfamily
XI02_RS03255	COG0577	efflux transmembrane transporter activity
XI02_RS03270	COG2271	Major facilitator Superfamily
XI02_RS03275	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
XI02_RS03290	COG2271	Major facilitator Superfamily
XI02_RS03300	COG3547	Transposase (IS116 IS110 IS902 family)
XI02_RS03310	COG4771	TonB-dependent receptor
XI02_RS03315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XI02_RS03320	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
XI02_RS03330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XI02_RS03340	COG0737	Belongs to the 5'-nucleotidase family
XI02_RS03350	COG3258	Cytochrome c
XI02_RS03380	COG2814	Major facilitator Superfamily
XI02_RS03390	COG2514	catechol 2,3-dioxygenase activity
XI02_RS03400	COG1960	acyl-CoA dehydrogenase activity
XI02_RS03405	COG1960	acyl-CoA dehydrogenase activity
XI02_RS03410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XI02_RS03425	COG1294	oxidase, subunit
XI02_RS03430	COG1271	oxidase subunit
XI02_RS03445	COG1595	DNA-templated transcription, initiation
XI02_RS03455	COG1643	Atp-dependent helicase
XI02_RS03460	COG1953	Uracil, thiamine, allantoin
XI02_RS03465	COG3577	Aspartyl protease
XI02_RS03480	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XI02_RS03495	COG1522	sequence-specific DNA binding
XI02_RS03500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XI02_RS03520	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
XI02_RS03525	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XI02_RS03530	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
XI02_RS03540	COG2223	nitrite transmembrane transporter activity
XI02_RS03550	COG0242	peptide deformylase activity
XI02_RS03555	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XI02_RS03560	COG0101	tRNA pseudouridine synthase activity
XI02_RS03565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XI02_RS03570	COG3152	Membrane
XI02_RS03575	COG2171	N-acyltransferase activity
XI02_RS03590	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XI02_RS03600	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XI02_RS03605	COG0706	membrane insertase activity
XI02_RS03615	COG0230	Belongs to the bacterial ribosomal protein bL34 family
XI02_RS03630	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XI02_RS03650	COG1129	ABC transporter
XI02_RS03665	COG1879	ABC-type sugar transport system periplasmic component
XI02_RS03670	COG1172	Belongs to the binding-protein-dependent transport system permease family
XI02_RS03695	COG1335	isochorismatase
XI02_RS03710	COG4585	Histidine kinase
XI02_RS03715	COG2197	response regulator
XI02_RS03745	COG1970	mechanosensitive ion channel activity
XI02_RS03755	COG2226	methyltransferase
XI02_RS03760	COG1959	2 iron, 2 sulfur cluster binding
XI02_RS03770	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XI02_RS03775	COG0668	transmembrane transport
XI02_RS03785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XI02_RS03790	COG0702	epimerase
XI02_RS03805	COG3284	Transcriptional regulator
XI02_RS03815	COG2003	Belongs to the UPF0758 family
XI02_RS03845	COG2433	Pfam Transposase IS66
XI02_RS03850	COG3436	PFAM IS66 Orf2 family protein
XI02_RS03885	COG1484	DNA-dependent DNA replication
XI02_RS03890	COG4584	PFAM Integrase catalytic
XI02_RS03925	COG2925	Exonuclease
XI02_RS03970	COG2226	methyltransferase
XI02_RS03975	COG1278	Cold shock
XI02_RS03985	COG5489	Protein of unknown function (DUF736)
XI02_RS04025	COG1192	Involved in chromosome partitioning
XI02_RS04080	COG1396	sequence-specific DNA binding
XI02_RS04085	COG0765	amino acid transport
XI02_RS04090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XI02_RS04095	COG3436	PFAM IS66 Orf2 family protein
XI02_RS04100	COG2963	transposase activity
XI02_RS04140	COG4716	Myosin-crossreactive antigen
XI02_RS04165	COG2010	Cytochrome c
XI02_RS04205	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XI02_RS04230	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XI02_RS04230	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XI02_RS04295	COG0776	regulation of translation
XI02_RS04335	COG3547	Transposase (IS116 IS110 IS902 family)
XI02_RS04365	COG5265	(ABC) transporter
XI02_RS04395	COG4962	Type ii secretion system protein e
XI02_RS04400	COG3838	Conjugal transfer protein Trbc
XI02_RS04410	COG3451	type IV secretory pathway VirB4
XI02_RS04430	COG3701	Conjugal transfer protein
XI02_RS04440	COG2948	multi-organism process
XI02_RS04450	COG0596	Alpha beta hydrolase
XI02_RS04470	COG0583	DNA-binding transcription factor activity
XI02_RS04480	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XI02_RS04585	COG1278	Cold shock
XI02_RS04650	COG4584	PFAM Integrase catalytic
XI02_RS04655	COG1484	DNA-dependent DNA replication
XI02_RS04675	COG3436	PFAM IS66 Orf2 family protein
XI02_RS04705	COG0405	Gamma-glutamyltransferase
XI02_RS04715	COG1181	Belongs to the D-alanine--D-alanine ligase family
XI02_RS04730	COG1484	DNA-dependent DNA replication
XI02_RS04735	COG4584	PFAM Integrase catalytic
XI02_RS04770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XI02_RS04840	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
XI02_RS04920	COG0300	oxidoreductase activity
XI02_RS04925	COG1376	ErfK ybiS ycfS ynhG family protein
XI02_RS04930	COG1309	transcriptional regulator
XI02_RS04945	COG3293	Transposase
XI02_RS04975	COG0419	ATPase involved in DNA repair
XI02_RS04985	COG4804	nuclease activity
XI02_RS04990	COG0582	viral genome integration into host DNA
XI02_RS04995	COG2003	Belongs to the UPF0758 family
XI02_RS05005	COG0024	Methionine aminopeptidase
XI02_RS05010	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
XI02_RS05010	COG3264	Mechanosensitive ion channel
XI02_RS05015	COG3263	regulation of cellular component size
XI02_RS05025	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XI02_RS05030	COG4149	molybdate abc transporter
XI02_RS05035	COG0725	ABC transporter, periplasmic molybdate-binding protein
XI02_RS05045	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
XI02_RS05055	COG5001	Diguanylate cyclase
XI02_RS05085	COG2010	Cytochrome c
XI02_RS05105	COG1960	acyl-CoA dehydrogenase activity
XI02_RS05110	COG2223	nitrite transmembrane transporter activity
XI02_RS05120	COG0481	GTPase activity
XI02_RS05135	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XI02_RS05140	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
XI02_RS05140	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
XI02_RS05150	COG2205	protein histidine kinase activity
XI02_RS05155	COG0745	RESPONSE REGULATOR receiver
XI02_RS05170	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
XI02_RS05175	COG3547	Transposase (IS116 IS110 IS902 family)
XI02_RS05190	COG0058	SHG alpha-glucan phosphorylase activity
XI02_RS05215	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XI02_RS05220	COG0625	glutathione transferase activity
XI02_RS05225	COG1280	lysine exporter protein (LysE YggA)
XI02_RS05230	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XI02_RS05230	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XI02_RS05235	COG3547	Transposase (IS116 IS110 IS902 family)
XI02_RS05245	COG3437	response regulator, receiver
XI02_RS05245	COG0784	Response regulator, receiver
XI02_RS05250	COG4191	Histidine kinase
XI02_RS05255	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XI02_RS05275	COG0601	transmembrane transport
XI02_RS05280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XI02_RS05285	COG4172	Belongs to the ABC transporter superfamily
XI02_RS05305	COG1802	Transcriptional regulator
XI02_RS05320	COG3320	Male sterility
XI02_RS05320	COG1022	Amp-dependent synthetase and ligase
XI02_RS05330	COG2124	cytochrome p450
XI02_RS05365	COG1595	DNA-templated transcription, initiation
XI02_RS05385	COG4177	L-phenylalanine transmembrane transporter activity
XI02_RS05390	COG0411	ABC transporter
XI02_RS05410	COG1414	Transcriptional regulator
XI02_RS05415	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XI02_RS05420	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XI02_RS05450	COG2885	chlorophyll binding
XI02_RS05465	COG0596	Alpha beta hydrolase
XI02_RS05480	COG5002	protein histidine kinase activity
XI02_RS05485	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XI02_RS05490	COG0573	inorganic phosphate transmembrane transporter activity
XI02_RS05495	COG0581	inorganic phosphate transmembrane transporter activity
XI02_RS05500	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XI02_RS05505	COG0704	Plays a role in the regulation of phosphate uptake
XI02_RS05510	COG0745	RESPONSE REGULATOR receiver
XI02_RS05520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XI02_RS05525	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XI02_RS05535	COG2967	ApaG domain
XI02_RS05555	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XI02_RS05600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XI02_RS05610	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XI02_RS05615	COG3474	cytochrome
XI02_RS05620	COG4166	transmembrane transport
XI02_RS05625	COG4166	transmembrane transport
XI02_RS05630	COG4174	ABC transporter (Permease)
XI02_RS05635	COG4239	(ABC) transporter, permease
XI02_RS05640	COG4172	Belongs to the ABC transporter superfamily
XI02_RS05650	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XI02_RS05685	COG4964	Belongs to the GSP D family
XI02_RS05730	COG1278	Cold shock
XI02_RS05735	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
XI02_RS05740	COG0513	Belongs to the DEAD box helicase family
XI02_RS05760	COG0411	ABC transporter
XI02_RS05770	COG0829	nickel cation binding
XI02_RS05775	COG0831	urea catabolic process
XI02_RS05780	COG0832	Belongs to the urease beta subunit family
XI02_RS05785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XI02_RS05790	COG0804	urea catabolic process
XI02_RS05805	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
XI02_RS05810	COG0830	nickel cation binding
XI02_RS05815	COG3547	Transposase (IS116 IS110 IS902 family)
XI02_RS05820	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
XI02_RS05830	COG1858	cytochrome C peroxidase
XI02_RS05845	COG3300	MHYT domain
XI02_RS05845	COG5001	Diguanylate cyclase
XI02_RS05860	COG0784	Response regulator, receiver
XI02_RS05865	COG2124	cytochrome p450
XI02_RS05900	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XI02_RS05950	COG0628	permease
XI02_RS05960	COG1376	ErfK ybiS ycfS ynhG family protein
XI02_RS05960	COG1388	LysM domain
XI02_RS05975	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XI02_RS05995	COG0175	sulfate reduction
XI02_RS06000	COG1648	precorrin-2 dehydrogenase activity
XI02_RS06000	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XI02_RS06010	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XI02_RS06020	COG0175	sulfate reduction
XI02_RS06025	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XI02_RS06030	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XI02_RS06035	COG4208	sulfate ABC transporter
XI02_RS06040	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XI02_RS06055	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS06080	COG1678	Uncharacterized ACR, COG1678
XI02_RS06090	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS06095	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS06100	COG3237	CsbD-like
XI02_RS06110	COG2951	lytic endotransglycosylase activity
XI02_RS06115	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XI02_RS06125	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
XI02_RS06135	COG0667	Aldo Keto reductase
XI02_RS06145	COG1051	belongs to the nudix hydrolase family
XI02_RS06180	COG2358	TRAP transporter, solute receptor (TAXI family
XI02_RS06195	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS06230	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XI02_RS06235	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
XI02_RS06240	COG0328	RNA-DNA hybrid ribonuclease activity
XI02_RS06255	COG0318	PFAM AMP-dependent synthetase and ligase
XI02_RS06260	COG1686	Belongs to the peptidase S11 family
XI02_RS06265	COG1132	(ABC) transporter
XI02_RS06280	COG0140	phosphoribosyl-ATP diphosphatase activity
XI02_RS06285	COG1238	metal cluster binding
XI02_RS06310	COG0318	PFAM AMP-dependent synthetase and ligase
XI02_RS06370	COG1960	acyl-CoA dehydrogenase activity
XI02_RS06385	COG1960	acyl-CoA dehydrogenase activity
XI02_RS06390	COG0183	Belongs to the thiolase family
XI02_RS06395	COG1024	Enoyl-CoA hydratase
XI02_RS06395	COG1250	3-hydroxyacyl-CoA dehydrogenase
XI02_RS06450	COG0459	protein refolding
XI02_RS06455	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XI02_RS06460	COG0071	Belongs to the small heat shock protein (HSP20) family
XI02_RS06485	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XI02_RS06490	COG0459	protein refolding
XI02_RS06500	COG0071	Belongs to the small heat shock protein (HSP20) family
XI02_RS06505	COG0071	Belongs to the small heat shock protein (HSP20) family
XI02_RS06515	COG0071	Belongs to the small heat shock protein (HSP20) family
XI02_RS06520	COG0071	Belongs to the small heat shock protein (HSP20) family
XI02_RS06535	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XI02_RS06540	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
XI02_RS06560	COG3220	belongs to the UPF0276 family
XI02_RS06570	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XI02_RS06580	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS06585	COG0583	DNA-binding transcription factor activity
XI02_RS06665	COG1566	PFAM secretion protein HlyD family protein
XI02_RS06675	COG4977	sequence-specific DNA binding
XI02_RS06690	COG0318	PFAM AMP-dependent synthetase and ligase
XI02_RS06705	COG1473	amidohydrolase
XI02_RS06710	COG1760	l-serine dehydratase
XI02_RS06720	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XI02_RS06745	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XI02_RS06745	COG0596	Alpha beta hydrolase
XI02_RS06745	COG2226	methyltransferase
XI02_RS06755	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS06760	COG0318	PFAM AMP-dependent synthetase and ligase
XI02_RS06770	COG2271	Major facilitator Superfamily
XI02_RS06775	COG0563	adenylate kinase activity
XI02_RS06785	COG0300	oxidoreductase activity
XI02_RS06795	COG0583	DNA-binding transcription factor activity
XI02_RS06810	COG3781	membrane
XI02_RS06815	COG3237	CsbD-like
XI02_RS06820	COG0243	molybdopterin cofactor binding
XI02_RS06830	COG1294	oxidase, subunit
XI02_RS06840	COG0668	transmembrane transport
XI02_RS06850	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XI02_RS06865	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XI02_RS06885	COG0484	heat shock protein binding
XI02_RS06900	COG2204	response regulator
XI02_RS06905	COG3852	Histidine kinase
XI02_RS06925	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XI02_RS06935	COG0542	response to heat
XI02_RS06955	COG2837	iron assimilation
XI02_RS06975	COG1376	ErfK ybiS ycfS ynhG family protein
XI02_RS06980	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS07030	COG3485	protocatechuate 3,4-dioxygenase
XI02_RS07035	COG3485	protocatechuate 3,4-dioxygenase
XI02_RS07050	COG3395	kinase activity
XI02_RS07055	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XI02_RS07060	COG1349	DNA-binding transcription factor activity
XI02_RS07080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XI02_RS07085	COG2368	4-hydroxyphenylacetate
XI02_RS07110	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XI02_RS07115	COG3842	ATPase activity
XI02_RS07125	COG0154	amidase activity
XI02_RS07135	COG0582	viral genome integration into host DNA
XI02_RS07145	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XI02_RS07200	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XI02_RS07200	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
XI02_RS07210	COG0583	DNA-binding transcription factor activity
XI02_RS07215	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS07230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XI02_RS07265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XI02_RS07270	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XI02_RS07275	COG0483	inositol monophosphate 1-phosphatase activity
XI02_RS07290	COG3588	fructose-bisphosphate aldolase
XI02_RS07300	COG0126	phosphoglycerate kinase activity
XI02_RS07330	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XI02_RS07335	COG1692	metallophosphoesterase
XI02_RS07345	COG0840	transmembrane signaling receptor activity
XI02_RS07355	COG0217	transcriptional regulatory protein
XI02_RS07360	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
XI02_RS07365	COG0632	four-way junction helicase activity
XI02_RS07370	COG2255	four-way junction helicase activity
XI02_RS07375	COG1408	metallophosphoesterase
XI02_RS07380	COG0824	Thioesterase
XI02_RS07390	COG0625	glutathione transferase activity
XI02_RS07395	COG1309	transcriptional regulator
XI02_RS07410	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XI02_RS07420	COG3795	YCII-related domain
XI02_RS07425	COG4941	Belongs to the sigma-70 factor family
XI02_RS07460	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XI02_RS07465	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
XI02_RS07475	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS07505	COG1309	transcriptional regulator
XI02_RS07550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
XI02_RS07555	COG0803	Belongs to the bacterial solute-binding protein 9 family
XI02_RS07560	COG0523	cobalamin synthesis protein
XI02_RS07580	COG4689	acetoacetate decarboxylase
XI02_RS07590	COG0251	oxidation-reduction process
XI02_RS07625	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
XI02_RS07635	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XI02_RS07640	COG0330	HflC and HflK could
XI02_RS07675	COG0070	glutamate synthase
XI02_RS07675	COG0069	glutamate synthase activity
XI02_RS07675	COG0067	glutamate synthase
XI02_RS07685	COG0071	Belongs to the small heat shock protein (HSP20) family
XI02_RS07715	COG0583	DNA-binding transcription factor activity
XI02_RS07725	COG0483	inositol monophosphate 1-phosphatase activity
XI02_RS07750	COG0583	DNA-binding transcription factor activity
XI02_RS07790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XI02_RS07795	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XI02_RS07810	COG4770	biotin carboxylase activity
XI02_RS07865	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XI02_RS07890	COG4977	sequence-specific DNA binding
XI02_RS07915	COG2146	nitrite reductase [NAD(P)H] activity
XI02_RS07920	COG0625	glutathione transferase activity
XI02_RS07925	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XI02_RS07925	COG1017	nitric oxide dioxygenase activity
XI02_RS07935	COG1309	transcriptional regulator
XI02_RS08025	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
XI02_RS08040	COG0574	Belongs to the PEP-utilizing enzyme family
XI02_RS08040	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XI02_RS08045	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
XI02_RS08060	COG2723	6-phospho-beta-galactosidase activity
XI02_RS08090	COG0459	protein refolding
XI02_RS08095	COG0071	Belongs to the small heat shock protein (HSP20) family
XI02_RS08125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XI02_RS08190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XI02_RS08200	COG0842	Transport permease protein
XI02_RS08220	COG0516	GMP reductase activity
XI02_RS08220	COG0517	IMP dehydrogenase activity
XI02_RS08240	COG0277	FAD linked oxidase domain protein
XI02_RS08310	COG1012	belongs to the aldehyde dehydrogenase family
XI02_RS08315	COG2005	Transcriptional regulator
XI02_RS08320	COG1902	pentaerythritol trinitrate reductase activity
XI02_RS08380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XI02_RS08385	COG0765	amino acid transport
XI02_RS08390	COG0765	amino acid transport
XI02_RS08395	COG1126	abc transporter atp-binding protein
XI02_RS08405	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XI02_RS08490	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
XI02_RS08525	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XI02_RS08535	COG0655	NAD(P)H dehydrogenase (quinone) activity
XI02_RS08540	COG1741	Belongs to the pirin family
XI02_RS08550	COG0583	DNA-binding transcription factor activity
XI02_RS08570	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XI02_RS08590	COG0257	Belongs to the bacterial ribosomal protein bL36 family
XI02_RS08605	COG2267	carboxylic ester hydrolase activity
XI02_RS08610	COG0028	Belongs to the TPP enzyme family
XI02_RS08615	COG3474	cytochrome
XI02_RS08620	COG0277	FAD linked oxidase domain protein
XI02_RS08645	COG0640	Transcriptional regulator
XI02_RS08650	COG0277	FAD linked oxidase domain protein
XI02_RS08655	COG0247	lactate metabolic process
XI02_RS08670	COG4178	(ABC) transporter
XI02_RS08675	COG1620	l-lactate permease
XI02_RS08690	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
XI02_RS08690	COG2169	Transcriptional regulator
XI02_RS08730	COG0459	protein refolding
XI02_RS08735	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XI02_RS08750	COG1376	ErfK ybiS ycfS ynhG family protein
XI02_RS08750	COG1388	LysM domain
XI02_RS08755	COG3416	Protein conserved in bacteria
XI02_RS08765	COG0463	Glycosyl transferase, family 2
XI02_RS08775	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
XI02_RS08790	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XI02_RS08800	COG0312	modulator of DNA gyrase
XI02_RS08820	COG1519	Transferase
XI02_RS08825	COG1663	tetraacyldisaccharide 4'-kinase activity
XI02_RS08840	COG1570	exodeoxyribonuclease VII activity
XI02_RS08845	COG0151	Belongs to the GarS family
XI02_RS08855	COG1960	acyl-CoA dehydrogenase activity
XI02_RS08860	COG0596	Alpha beta hydrolase
XI02_RS08865	COG0590	tRNA wobble adenosine to inosine editing
XI02_RS08870	COG1187	pseudouridine synthase activity
XI02_RS08875	COG0742	ribosomal rna small subunit methyltransferase
XI02_RS08890	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XI02_RS08930	COG0612	Peptidase, M16
XI02_RS08935	COG0612	Peptidase, M16
XI02_RS08945	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XI02_RS08950	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
XI02_RS08960	COG0196	riboflavin kinase activity
XI02_RS08965	COG0745	RESPONSE REGULATOR receiver
XI02_RS08975	COG5001	Diguanylate cyclase
XI02_RS08975	COG5002	protein histidine kinase activity
XI02_RS08980	COG2890	protein-(glutamine-N5) methyltransferase activity
XI02_RS08985	COG0314	molybdopterin synthase activity
XI02_RS08995	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XI02_RS09000	COG0322	excinuclease ABC activity
XI02_RS09005	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
XI02_RS09010	COG1278	Cold shock
XI02_RS09015	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XI02_RS09045	COG2205	protein histidine kinase activity
XI02_RS09050	COG0745	RESPONSE REGULATOR receiver
XI02_RS09055	COG1846	Transcriptional regulator
XI02_RS09060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XI02_RS09065	COG0124	histidyl-tRNA synthetase
XI02_RS09070	COG1942	4-Oxalocrotonate Tautomerase
XI02_RS09090	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XI02_RS09095	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS09100	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XI02_RS09115	COG1496	oxidoreductase activity
XI02_RS09125	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XI02_RS09140	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XI02_RS09145	COG0193	aminoacyl-tRNA hydrolase activity
XI02_RS09150	COG0012	GTP binding
XI02_RS09160	COG1937	Protein conserved in bacteria
XI02_RS09170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XI02_RS09175	COG0583	DNA-binding transcription factor activity
XI02_RS09180	COG0492	ferredoxin-NADP+ reductase activity
XI02_RS09185	COG1522	sequence-specific DNA binding
XI02_RS09190	COG2259	Doxx family
XI02_RS09200	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XI02_RS09205	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XI02_RS09235	COG0640	Transcriptional regulator
XI02_RS09270	COG4948	Mandelate Racemase Muconate Lactonizing
XI02_RS09280	COG0505	Belongs to the CarA family
XI02_RS09295	COG0302	gtp cyclohydrolase
XI02_RS09305	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XI02_RS09325	COG0640	Transcriptional regulator
XI02_RS09340	COG1280	lysine exporter protein (LysE YggA)
XI02_RS09350	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XI02_RS09355	COG2080	2 iron, 2 sulfur cluster binding
XI02_RS09375	COG1917	Cupin 2, conserved barrel domain protein
XI02_RS09375	COG4977	sequence-specific DNA binding
XI02_RS09380	COG2207	Transcriptional regulator
XI02_RS09395	COG4774	siderophore transport
XI02_RS09445	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XI02_RS09490	COG1280	lysine exporter protein (LysE YggA)
XI02_RS09495	COG3706	GGDEF domain
XI02_RS09495	COG4251	negative regulation of phosphorylation
XI02_RS09495	COG5001	Diguanylate cyclase
XI02_RS09495	COG2203	Gaf domain
XI02_RS09505	COG1376	ErfK ybiS ycfS ynhG family protein
XI02_RS09510	COG3119	arylsulfatase activity
XI02_RS09525	COG3119	arylsulfatase activity
XI02_RS09530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XI02_RS09535	COG0564	pseudouridine synthase activity
XI02_RS09545	COG0723	plastoquinol--plastocyanin reductase activity
XI02_RS09675	COG2161	toxin-antitoxin pair type II binding
XI02_RS09715	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
XI02_RS09725	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
XI02_RS09760	COG4584	PFAM Integrase catalytic
XI02_RS09765	COG1484	DNA-dependent DNA replication
XI02_RS09785	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XI02_RS09795	COG2223	nitrite transmembrane transporter activity
XI02_RS09800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XI02_RS09810	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XI02_RS09815	COG4566	intracellular signal transduction
XI02_RS09820	COG4566	intracellular signal transduction
XI02_RS09825	COG4191	Histidine kinase
XI02_RS09835	COG1301	dicarboxylic acid transport
XI02_RS09860	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XI02_RS09875	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
XI02_RS09880	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
XI02_RS09885	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
XI02_RS09890	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
XI02_RS09895	COG0298	carbon dioxide binding
XI02_RS09905	COG1773	rubredoxin
XI02_RS09915	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
XI02_RS09920	COG0375	protein maturation
XI02_RS09925	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
XI02_RS09940	COG0409	Hydrogenase expression formation protein
XI02_RS09945	COG0309	Hydrogenase expression formation protein (HypE)
XI02_RS09950	COG0686	Belongs to the AlaDH PNT family
XI02_RS09955	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XI02_RS09960	COG0719	Fe-S assembly protein
XI02_RS09965	COG0396	ATPase activity
XI02_RS09975	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XI02_RS09985	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
XI02_RS09990	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
XI02_RS09995	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
XI02_RS10010	COG5420	small protein containing a coiled-coil domain
XI02_RS10015	COG3383	formate dehydrogenase (NAD+) activity
XI02_RS10035	COG0316	Belongs to the HesB IscA family
XI02_RS10045	COG1104	cysteine desulfurase activity
XI02_RS10050	COG5554	nitrogen fixation
XI02_RS10060	COG0535	radical SAM domain protein
XI02_RS10065	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XI02_RS10075	COG5554	nitrogen fixation
XI02_RS10095	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XI02_RS10105	COG3411	Ferredoxin
XI02_RS10110	COG3047	cAMP biosynthetic process
XI02_RS10140	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
XI02_RS10145	COG0644	oxidoreductase
XI02_RS10150	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
XI02_RS10155	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XI02_RS10160	COG0450	alkyl hydroperoxide reductase
XI02_RS10165	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XI02_RS10165	COG1618	nucleotide phosphatase activity, acting on free nucleotides
XI02_RS10170	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XI02_RS10210	COG4886	Leucine-rich repeat (LRR) protein
XI02_RS10225	COG1484	DNA-dependent DNA replication
XI02_RS10230	COG4584	PFAM Integrase catalytic
XI02_RS10235	COG0612	Peptidase, M16
XI02_RS10240	COG0612	Peptidase, M16
XI02_RS10260	COG5010	COG0457 FOG TPR repeat
XI02_RS10265	COG4789	Type iii secretion
XI02_RS10310	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XI02_RS10310	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XI02_RS10315	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XI02_RS10340	COG4669	(LipO)protein
XI02_RS10350	COG1317	bacterial-type flagellum organization
XI02_RS10355	COG1157	protein secretion by the type III secretion system
XI02_RS10365	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
XI02_RS10370	COG4790	Type iii secretion
XI02_RS10375	COG4794	Type iii secretion
XI02_RS10380	COG4791	protein targeting
XI02_RS10385	COG4792	protein secretion
XI02_RS10390	COG5461	TIGRFAM pilus (Caulobacter type) biogenesis lipoprotein CpaD
XI02_RS10395	COG4964	Belongs to the GSP D family
XI02_RS10400	COG0745	RESPONSE REGULATOR receiver
XI02_RS10440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XI02_RS10480	COG1484	DNA-dependent DNA replication
XI02_RS10485	COG4584	PFAM Integrase catalytic
XI02_RS10510	COG5265	(ABC) transporter
XI02_RS10515	COG2963	transposase activity
XI02_RS10520	COG3436	PFAM IS66 Orf2 family protein
XI02_RS10535	COG2433	Pfam Transposase IS66
XI02_RS10540	COG3318	Belongs to the UPF0149 family
XI02_RS10580	COG1487	ribonuclease activity
XI02_RS10585	COG4691	Plasmid stability protein
XI02_RS10620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XI02_RS10635	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XI02_RS10640	COG0697	spore germination
XI02_RS10650	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XI02_RS10660	COG0765	amino acid transport
XI02_RS10665	COG1126	abc transporter atp-binding protein
XI02_RS10675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XI02_RS10685	COG1522	sequence-specific DNA binding
XI02_RS10710	COG3318	Belongs to the UPF0149 family
XI02_RS10720	COG4974	Belongs to the 'phage' integrase family
XI02_RS10725	COG0582	viral genome integration into host DNA
XI02_RS10730	COG4974	Belongs to the 'phage' integrase family
XI02_RS10755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XI02_RS10760	COG0747	negative chemotaxis
XI02_RS10770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XI02_RS10785	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XI02_RS10805	COG2124	cytochrome p450
XI02_RS10815	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS10820	COG2124	cytochrome p450
XI02_RS10825	COG0142	geranyltranstransferase activity
XI02_RS10830	COG1657	PFAM Prenyltransferase squalene oxidase
XI02_RS10860	COG1448	Aminotransferase
XI02_RS10880	COG0459	protein refolding
XI02_RS10980	COG0512	Glutamine amidotransferase of anthranilate synthase
XI02_RS10985	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XI02_RS10995	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XI02_RS11050	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
XI02_RS11050	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
XI02_RS11060	COG0542	response to heat
XI02_RS11110	COG2010	Cytochrome c
XI02_RS11120	COG4584	PFAM Integrase catalytic
XI02_RS11125	COG1484	DNA-dependent DNA replication
XI02_RS11130	COG4584	PFAM Integrase catalytic
XI02_RS11135	COG4584	PFAM Integrase catalytic
XI02_RS11135	COG2390	Transcriptional regulator
XI02_RS11160	COG0583	DNA-binding transcription factor activity
XI02_RS11170	COG3842	ATPase activity
XI02_RS11175	COG1175	transmembrane transport
XI02_RS11180	COG1653	transport
XI02_RS11195	COG0154	amidase activity
XI02_RS11230	COG0395	ABC-type sugar transport system, permease component
XI02_RS11235	COG1653	transport
XI02_RS11250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XI02_RS11320	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XI02_RS11325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XI02_RS11330	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XI02_RS11335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XI02_RS11345	COG1213	nucleotidyl transferase
XI02_RS11415	COG1505	serine-type exopeptidase activity
XI02_RS11450	COG1278	Cold shock
XI02_RS11475	COG4886	Leucine-rich repeat (LRR) protein
XI02_RS11500	COG3620	sequence-specific DNA binding
XI02_RS11505	COG3550	peptidyl-serine autophosphorylation
XI02_RS11515	COG3177	Filamentation induced by cAMP protein fic
XI02_RS11575	COG0287	Prephenate dehydrogenase
XI02_RS11580	COG5434	Belongs to the glycosyl hydrolase 28 family
XI02_RS11595	COG3594	Acyltransferase
XI02_RS11620	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XI02_RS11625	COG0730	response to heat
XI02_RS11635	COG2771	luxR family
XI02_RS11655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XI02_RS11665	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XI02_RS11705	COG1215	transferase activity, transferring glycosyl groups
XI02_RS11710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XI02_RS11715	COG2192	nodulation
XI02_RS11720	COG1131	(ABC) transporter
XI02_RS11725	COG0842	Transport permease protein
XI02_RS11730	COG2192	nodulation
XI02_RS11745	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS11750	COG3604	Transcriptional regulator
XI02_RS11760	COG1396	sequence-specific DNA binding
XI02_RS11765	COG4886	Leucine-rich repeat (LRR) protein
XI02_RS11770	COG1484	DNA-dependent DNA replication
XI02_RS11775	COG4584	PFAM Integrase catalytic
XI02_RS11795	COG3609	addiction module antidote protein, CC2985 family
XI02_RS11805	COG2086	electron transfer activity
XI02_RS11835	COG0318	PFAM AMP-dependent synthetase and ligase
XI02_RS11855	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XI02_RS11865	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XI02_RS11905	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XI02_RS11925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XI02_RS11965	COG3436	PFAM IS66 Orf2 family protein
XI02_RS11975	COG0459	protein refolding
XI02_RS11980	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XI02_RS11985	COG0275	rRNA processing
XI02_RS12010	COG2963	transposase activity
XI02_RS12015	COG3436	PFAM IS66 Orf2 family protein
XI02_RS12020	COG2433	Pfam Transposase IS66
XI02_RS12025	COG3318	Belongs to the UPF0149 family
XI02_RS12040	COG2814	Major facilitator Superfamily
XI02_RS12065	COG0156	8-amino-7-oxononanoate synthase activity
XI02_RS12095	COG2433	Pfam Transposase IS66
XI02_RS12100	COG3436	PFAM IS66 Orf2 family protein
XI02_RS12105	COG2963	transposase activity
XI02_RS12125	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
XI02_RS12130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XI02_RS12140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XI02_RS12150	COG4566	intracellular signal transduction
XI02_RS12155	COG4191	Histidine kinase
XI02_RS12180	COG3278	Belongs to the heme-copper respiratory oxidase family
XI02_RS12195	COG2010	Cytochrome c
XI02_RS12210	COG2217	Heavy metal translocating P-type atpase
XI02_RS12230	COG0175	sulfate reduction
XI02_RS12260	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XI02_RS12275	COG0174	glutamine synthetase
XI02_RS12285	COG4584	PFAM Integrase catalytic
XI02_RS12290	COG1484	DNA-dependent DNA replication
XI02_RS12310	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
XI02_RS12315	COG0071	Belongs to the small heat shock protein (HSP20) family
XI02_RS12400	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XI02_RS12405	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XI02_RS12410	COG0459	protein refolding
XI02_RS12420	COG0071	Belongs to the small heat shock protein (HSP20) family
XI02_RS12430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XI02_RS12435	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XI02_RS12450	COG0071	Belongs to the small heat shock protein (HSP20) family
XI02_RS12455	COG0071	Belongs to the small heat shock protein (HSP20) family
XI02_RS12475	COG5489	Protein of unknown function (DUF736)
XI02_RS12525	COG4584	PFAM Integrase catalytic
XI02_RS12530	COG1484	DNA-dependent DNA replication
XI02_RS12535	COG4886	Leucine-rich repeat (LRR) protein
XI02_RS12550	COG0681	Belongs to the peptidase S26 family
XI02_RS12555	COG1196	nuclear chromosome segregation
XI02_RS12555	COG0739	heme binding
XI02_RS12555	COG0741	lytic transglycosylase activity
XI02_RS12595	COG4962	Type ii secretion system protein e
XI02_RS12600	COG3838	Conjugal transfer protein Trbc
XI02_RS12610	COG3451	type IV secretory pathway VirB4
XI02_RS12655	COG0546	phosphoglycolate phosphatase activity
XI02_RS12685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XI02_RS12710	COG4774	siderophore transport
XI02_RS12720	COG4638	Rieske (2fe-2S)
XI02_RS12735	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS12745	COG1960	acyl-CoA dehydrogenase activity
XI02_RS12755	COG1172	Belongs to the binding-protein-dependent transport system permease family
XI02_RS12765	COG1022	Amp-dependent synthetase and ligase
XI02_RS12785	COG1309	transcriptional regulator
XI02_RS12805	COG0297	glycogen (starch) synthase activity
XI02_RS12810	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
XI02_RS12835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XI02_RS12850	COG0477	Major facilitator Superfamily
XI02_RS12865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XI02_RS12870	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XI02_RS12880	COG4597	amino acid ABC transporter
XI02_RS12885	COG0765	amino acid transport
XI02_RS12900	COG2188	Transcriptional regulator
XI02_RS12905	COG0154	amidase activity
XI02_RS12910	COG0154	amidase activity
XI02_RS12950	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
XI02_RS12955	COG1335	isochorismatase
XI02_RS12960	COG0181	hydroxymethylbilane synthase activity
XI02_RS12970	COG4638	Rieske (2fe-2S)
XI02_RS12980	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
XI02_RS12985	COG3454	Phosphonate metabolism
XI02_RS12995	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
XI02_RS13000	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
XI02_RS13010	COG3639	organic phosphonate transmembrane transporter activity
XI02_RS13015	COG2188	Transcriptional regulator
XI02_RS13020	COG3624	Phosphonate C-P lyase system protein PhnG
XI02_RS13025	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
XI02_RS13030	COG3626	phosphonate metabolism
XI02_RS13035	COG3627	carbon phosphorus lyase activity
XI02_RS13040	COG4107	phosphonate C-P lyase system protein PhnK
XI02_RS13045	COG4778	phosphonate C-P lyase system protein PhnL
XI02_RS13050	COG3454	Phosphonate metabolism
XI02_RS13055	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
XI02_RS13070	COG1309	transcriptional regulator
XI02_RS13075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XI02_RS13130	COG3964	amidohydrolase
XI02_RS13135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XI02_RS13150	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
XI02_RS13150	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
XI02_RS13155	COG1960	acyl-CoA dehydrogenase activity
XI02_RS13160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XI02_RS13180	COG1376	ErfK ybiS ycfS ynhG family protein
XI02_RS13185	COG0598	Magnesium transport protein CorA
XI02_RS13195	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS13200	COG0259	pyridoxamine-phosphate oxidase activity
XI02_RS13230	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XI02_RS13245	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
XI02_RS13260	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XI02_RS13265	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
XI02_RS13275	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XI02_RS13280	COG1722	exodeoxyribonuclease VII activity
XI02_RS13285	COG0123	including yeast histone deacetylase and acetoin utilization protein
XI02_RS13290	COG4085	toxin activity
XI02_RS13290	COG1525	nuclease
XI02_RS13290	COG0737	Belongs to the 5'-nucleotidase family
XI02_RS13295	COG1024	Enoyl-CoA hydratase
XI02_RS13300	COG2080	2 iron, 2 sulfur cluster binding
XI02_RS13305	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XI02_RS13310	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XI02_RS13340	COG0583	DNA-binding transcription factor activity
XI02_RS13345	COG1278	Cold shock
XI02_RS13375	COG0828	Belongs to the bacterial ribosomal protein bS21 family
XI02_RS13385	COG1960	acyl-CoA dehydrogenase activity
XI02_RS13440	COG0305	Participates in initiation and elongation during chromosome replication
XI02_RS13630	COG4584	PFAM Integrase catalytic
XI02_RS13635	COG1484	DNA-dependent DNA replication
XI02_RS13650	COG0732	type I restriction modification DNA specificity domain
XI02_RS13740	COG2189	Belongs to the N(4) N(6)-methyltransferase family
XI02_RS13755	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XI02_RS13760	COG3119	arylsulfatase activity
XI02_RS13770	COG3119	arylsulfatase activity
XI02_RS13780	COG3119	arylsulfatase activity
XI02_RS13785	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XI02_RS13800	COG4191	Histidine kinase
XI02_RS13805	COG4566	intracellular signal transduction
XI02_RS13825	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XI02_RS13845	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS13865	COG0489	protein tyrosine kinase activity
XI02_RS13880	COG0477	Major facilitator Superfamily
XI02_RS13890	COG1609	Transcriptional regulator
XI02_RS13895	COG3260	NADH ubiquinone oxidoreductase 20
XI02_RS13900	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XI02_RS13900	COG0649	NAD binding
XI02_RS13905	COG0651	ATP synthesis coupled electron transport
XI02_RS13915	COG0650	Formate hydrogenlyase subunit 4
XI02_RS13920	COG0651	ATP synthesis coupled electron transport
XI02_RS13935	COG1846	Transcriptional regulator
XI02_RS13940	COG1024	Enoyl-CoA hydratase
XI02_RS13960	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
XI02_RS13985	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS14000	COG3845	ABC transporter
XI02_RS14005	COG1335	isochorismatase
XI02_RS14010	COG1079	Belongs to the binding-protein-dependent transport system permease family
XI02_RS14015	COG1079	Belongs to the binding-protein-dependent transport system permease family
XI02_RS14030	COG4191	Histidine kinase
XI02_RS14040	COG0583	DNA-binding transcription factor activity
XI02_RS14045	COG2855	membrane
XI02_RS14050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XI02_RS14055	COG1335	isochorismatase
XI02_RS14065	COG2132	Multicopper oxidase
XI02_RS14070	COG3833	ABC-type maltose transport systems, permease component
XI02_RS14075	COG1175	transmembrane transport
XI02_RS14080	COG1653	transport
XI02_RS14090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XI02_RS14100	COG1980	fructose-bisphosphate aldolase activity
XI02_RS14110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XI02_RS14115	COG0601	transmembrane transport
XI02_RS14135	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XI02_RS14150	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XI02_RS14165	COG1116	anion transmembrane transporter activity
XI02_RS14170	COG1960	acyl-CoA dehydrogenase activity
XI02_RS14175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XI02_RS14180	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XI02_RS14215	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
XI02_RS14230	COG4948	Mandelate Racemase Muconate Lactonizing
XI02_RS14235	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
XI02_RS14250	COG1116	anion transmembrane transporter activity
XI02_RS14275	COG0444	Belongs to the ABC transporter superfamily
XI02_RS14295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XI02_RS14325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XI02_RS14365	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
XI02_RS14370	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XI02_RS14370	COG2010	Cytochrome c
XI02_RS14375	COG2080	2 iron, 2 sulfur cluster binding
XI02_RS14400	COG4177	L-phenylalanine transmembrane transporter activity
XI02_RS14460	COG0446	pyridine nucleotide-disulphide oxidoreductase
XI02_RS14475	COG2814	Major facilitator Superfamily
XI02_RS14490	COG4149	molybdate abc transporter
XI02_RS14495	COG1840	ABC-type Fe3 transport system, periplasmic component
XI02_RS14500	COG3842	ATPase activity
XI02_RS14510	COG2072	flavoprotein involved in K transport
XI02_RS14515	COG2015	COG2015, Alkyl sulfatase and related hydrolases
XI02_RS14525	COG1137	ATPase activity
XI02_RS14545	COG0438	transferase activity, transferring glycosyl groups
XI02_RS14550	COG1132	(ABC) transporter
XI02_RS14580	COG0297	glycogen (starch) synthase activity
XI02_RS14590	COG0747	negative chemotaxis
XI02_RS14595	COG0601	transmembrane transport
XI02_RS14600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XI02_RS14605	COG0444	Belongs to the ABC transporter superfamily
XI02_RS14620	COG0473	3-isopropylmalate dehydrogenase activity
XI02_RS14625	COG1396	sequence-specific DNA binding
XI02_RS14635	COG1301	dicarboxylic acid transport
XI02_RS14640	COG3920	Histidine kinase
XI02_RS14640	COG2202	Pas domain
XI02_RS14650	COG3485	protocatechuate 3,4-dioxygenase
XI02_RS14655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XI02_RS14665	COG1116	anion transmembrane transporter activity
XI02_RS14685	COG1012	belongs to the aldehyde dehydrogenase family
XI02_RS14690	COG0656	L-ascorbic acid biosynthetic process
XI02_RS14705	COG1063	alcohol dehydrogenase
XI02_RS14710	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS14720	COG0765	amino acid transport
XI02_RS14745	COG1522	sequence-specific DNA binding
XI02_RS14760	COG3386	PFAM SMP-30 Gluconolaconase
XI02_RS14765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XI02_RS14780	COG0129	dihydroxy-acid dehydratase activity
XI02_RS14800	COG1024	Enoyl-CoA hydratase
XI02_RS14815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XI02_RS14825	COG1309	transcriptional regulator
XI02_RS14830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XI02_RS14850	COG0673	inositol 2-dehydrogenase activity
XI02_RS14875	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XI02_RS14880	COG2124	cytochrome p450
XI02_RS14890	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
XI02_RS14890	COG0028	Belongs to the TPP enzyme family
XI02_RS14900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XI02_RS14905	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XI02_RS14915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XI02_RS14920	COG0601	transmembrane transport
XI02_RS14925	COG0747	negative chemotaxis
XI02_RS14930	COG4608	Belongs to the ABC transporter superfamily
XI02_RS14945	COG0405	Gamma-glutamyltransferase
XI02_RS14950	COG4608	Belongs to the ABC transporter superfamily
XI02_RS14955	COG0444	Belongs to the ABC transporter superfamily
XI02_RS14960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XI02_RS14965	COG0601	transmembrane transport
XI02_RS14970	COG0747	negative chemotaxis
XI02_RS14980	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XI02_RS14980	COG2226	methyltransferase
XI02_RS14980	COG0596	Alpha beta hydrolase
XI02_RS14990	COG2267	carboxylic ester hydrolase activity
XI02_RS14995	COG2124	cytochrome p450
XI02_RS14995	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XI02_RS15025	COG0456	acetyltransferase
XI02_RS15035	COG2733	membrane
XI02_RS15040	COG0596	Alpha beta hydrolase
XI02_RS15045	COG3327	negative regulation of DNA-templated transcription, initiation
XI02_RS15050	COG3396	Phenylacetate-CoA oxygenase
XI02_RS15055	COG3460	Phenylacetate-CoA oxygenase
XI02_RS15060	COG3396	Phenylacetate-CoA oxygenase
XI02_RS15065	COG2151	metal-sulfur cluster biosynthetic enzyme
XI02_RS15070	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XI02_RS15075	COG2050	protein possibly involved in aromatic compounds catabolism
XI02_RS15085	COG2827	Endonuclease containing a URI domain
XI02_RS15115	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XI02_RS15120	COG0477	Major facilitator Superfamily
XI02_RS15135	COG1309	transcriptional regulator
XI02_RS15150	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS15155	COG0473	3-isopropylmalate dehydrogenase activity
XI02_RS15160	COG3547	Transposase (IS116 IS110 IS902 family)
XI02_RS15165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XI02_RS15175	COG0583	DNA-binding transcription factor activity
XI02_RS15180	COG4336	lyase activity
XI02_RS15190	COG0559	Belongs to the binding-protein-dependent transport system permease family
XI02_RS15215	COG0235	Class ii aldolase
XI02_RS15220	COG2084	Dehydrogenase
XI02_RS15225	COG3622	Belongs to the hyi family
XI02_RS15245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XI02_RS15255	COG2070	2-Nitropropane dioxygenase
XI02_RS15260	COG0625	glutathione transferase activity
XI02_RS15270	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XI02_RS15275	COG3385	transposase activity
XI02_RS15280	COG1960	acyl-CoA dehydrogenase activity
XI02_RS15290	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS15295	COG1024	Enoyl-CoA hydratase
XI02_RS15310	COG1024	Enoyl-CoA hydratase
XI02_RS15315	COG1960	acyl-CoA dehydrogenase activity
XI02_RS15330	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS15335	COG1024	Enoyl-CoA hydratase
XI02_RS15345	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XI02_RS15350	COG3386	PFAM SMP-30 Gluconolaconase
XI02_RS15355	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS15410	COG3145	DNA-N1-methyladenine dioxygenase activity
XI02_RS15420	COG0028	Belongs to the TPP enzyme family
XI02_RS15425	COG0179	Fumarylacetoacetate (FAA) hydrolase
XI02_RS15445	COG3971	2-oxopent-4-enoate hydratase activity
XI02_RS15450	COG1846	Transcriptional regulator
XI02_RS15465	COG0559	Belongs to the binding-protein-dependent transport system permease family
XI02_RS15480	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
XI02_RS15490	COG2721	sulfolactate sulfo-lyase activity
XI02_RS15515	COG2203	Gaf domain
XI02_RS15515	COG4251	negative regulation of phosphorylation
XI02_RS15515	COG5001	Diguanylate cyclase
XI02_RS15515	COG3706	GGDEF domain
XI02_RS15525	COG4303	Ethanolamine ammonia lyase large subunit
XI02_RS15535	COG4302	ethanolamine ammonia-lyase activity
XI02_RS15555	COG1562	ergosterol biosynthetic process
XI02_RS15560	COG1562	ergosterol biosynthetic process
XI02_RS15565	COG1233	COG1233 Phytoene dehydrogenase and related
XI02_RS15570	COG1657	PFAM Prenyltransferase squalene oxidase
XI02_RS15575	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
XI02_RS15585	COG1960	acyl-CoA dehydrogenase activity
XI02_RS15595	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XI02_RS15600	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XI02_RS15605	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XI02_RS15675	COG4977	sequence-specific DNA binding
XI02_RS15720	COG2271	Major facilitator Superfamily
XI02_RS15750	COG1473	amidohydrolase
XI02_RS15765	COG0306	phosphate transporter
XI02_RS15770	COG1573	uracil-dna glycosylase
XI02_RS15785	COG0587	DNA-directed DNA polymerase activity
XI02_RS15790	COG0583	DNA-binding transcription factor activity
XI02_RS15795	COG2515	1-aminocyclopropane-1-carboxylate deaminase
XI02_RS15815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XI02_RS15830	COG3618	amidohydrolase
XI02_RS15845	COG1024	Enoyl-CoA hydratase
XI02_RS15905	COG1703	isobutyryl-CoA mutase activity
XI02_RS15930	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XI02_RS15940	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XI02_RS15955	COG0433	COG0433 Predicted ATPase
XI02_RS15980	COG4957	zinc ion binding
XI02_RS15985	COG2166	iron-sulfur cluster assembly
XI02_RS15995	COG2205	protein histidine kinase activity
XI02_RS16050	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XI02_RS16055	COG2983	Belongs to the UPF0260 family
XI02_RS16070	COG0559	Belongs to the binding-protein-dependent transport system permease family
XI02_RS16080	COG1129	ABC transporter
XI02_RS16095	COG0028	Belongs to the TPP enzyme family
XI02_RS16110	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
XI02_RS16185	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XI02_RS16220	COG0489	protein tyrosine kinase activity
XI02_RS16220	COG3206	protein involved in exopolysaccharide biosynthesis
XI02_RS16230	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XI02_RS16260	COG2226	methyltransferase
XI02_RS16265	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
XI02_RS16280	COG1063	alcohol dehydrogenase
XI02_RS16290	COG0438	transferase activity, transferring glycosyl groups
XI02_RS16330	COG1215	transferase activity, transferring glycosyl groups
XI02_RS16370	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
XI02_RS16375	COG0438	transferase activity, transferring glycosyl groups
XI02_RS16375	COG1216	Glycosyl transferase, family 2
XI02_RS16395	COG0438	transferase activity, transferring glycosyl groups
XI02_RS16400	COG1192	Involved in chromosome partitioning
XI02_RS16460	COG4235	cytochrome complex assembly
XI02_RS16465	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XI02_RS16470	COG1138	Cytochrome C-type biogenesis protein
XI02_RS16475	COG3088	subunit of a heme lyase
XI02_RS16480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XI02_RS16485	COG0745	RESPONSE REGULATOR receiver
XI02_RS16490	COG2205	protein histidine kinase activity
XI02_RS16495	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XI02_RS16505	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XI02_RS16510	COG3383	formate dehydrogenase (NAD+) activity
XI02_RS16525	COG0583	DNA-binding transcription factor activity
XI02_RS16530	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XI02_RS16535	COG2943	transferase activity, transferring hexosyl groups
XI02_RS16540	COG2205	protein histidine kinase activity
XI02_RS16540	COG2202	Pas domain
XI02_RS16550	COG1309	transcriptional regulator
XI02_RS16565	COG2015	COG2015, Alkyl sulfatase and related hydrolases
XI02_RS16575	COG0604	alcohol dehydrogenase
XI02_RS16575	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS16575	COG3321	synthase
XI02_RS16615	COG0477	Major facilitator Superfamily
XI02_RS16630	COG3655	Transcriptional regulator
XI02_RS16635	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XI02_RS16645	COG1802	Transcriptional regulator
XI02_RS16685	COG0477	Major facilitator Superfamily
XI02_RS16705	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XI02_RS16740	COG0129	dihydroxy-acid dehydratase activity
XI02_RS16760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XI02_RS16775	COG1172	Belongs to the binding-protein-dependent transport system permease family
XI02_RS16785	COG1172	Belongs to the binding-protein-dependent transport system permease family
XI02_RS16795	COG1129	ABC transporter
XI02_RS16805	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS16810	COG1024	Enoyl-CoA hydratase
XI02_RS16865	COG4191	Histidine kinase
XI02_RS16865	COG0784	Response regulator, receiver
XI02_RS16870	COG0583	DNA-binding transcription factor activity
XI02_RS16875	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XI02_RS16895	COG1850	ribulose-bisphosphate carboxylase activity
XI02_RS16900	COG4451	ribulose bisphosphate carboxylase, small
XI02_RS16910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XI02_RS16920	COG4213	ABC transporter substrate-binding protein
XI02_RS16930	COG4214	carbohydrate transport
XI02_RS16965	COG0778	Nitroreductase
XI02_RS16975	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XI02_RS16985	COG1492	cobalamin metabolic process
XI02_RS17030	COG2099	Precorrin-6x reductase
XI02_RS17045	COG2875	Belongs to the precorrin methyltransferase family
XI02_RS17050	COG1797	cobyrinic acid a,c-diamide synthase activity
XI02_RS17055	COG1648	precorrin-2 dehydrogenase activity
XI02_RS17055	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XI02_RS17085	COG0745	RESPONSE REGULATOR receiver
XI02_RS17090	COG2198	Histidine kinase
XI02_RS17090	COG0784	Response regulator, receiver
XI02_RS17090	COG5002	protein histidine kinase activity
XI02_RS17095	COG0683	leucine binding
XI02_RS17110	COG1129	ABC transporter
XI02_RS17135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XI02_RS17155	COG1228	amidohydrolase
XI02_RS17160	COG2986	histidine ammonia-lyase
XI02_RS17165	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XI02_RS17195	COG1137	ATPase activity
XI02_RS17200	COG3842	ATPase activity
XI02_RS17205	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XI02_RS17215	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XI02_RS17265	COG1137	ATPase activity
XI02_RS17270	COG0410	ABC transporter
XI02_RS17275	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS17285	COG0747	negative chemotaxis
XI02_RS17305	COG0405	Gamma-glutamyltransferase
XI02_RS17315	COG0523	cobalamin synthesis protein
XI02_RS17355	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XI02_RS17365	COG5441	Belongs to the UPF0261 family
XI02_RS17370	COG1012	belongs to the aldehyde dehydrogenase family
XI02_RS17375	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XI02_RS17385	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS17425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XI02_RS17455	COG3547	Transposase (IS116 IS110 IS902 family)
XI02_RS17530	COG3318	Belongs to the UPF0149 family
XI02_RS17535	COG2433	Pfam Transposase IS66
XI02_RS17540	COG3436	PFAM IS66 Orf2 family protein
XI02_RS17545	COG2963	transposase activity
XI02_RS17605	COG4964	Belongs to the GSP D family
XI02_RS17630	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XI02_RS17630	COG2755	lipolytic protein G-D-S-L family
XI02_RS17690	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XI02_RS17720	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XI02_RS17725	COG0517	IMP dehydrogenase activity
XI02_RS17725	COG0516	GMP reductase activity
XI02_RS17730	COG1414	Transcriptional regulator
XI02_RS17735	COG3960	tartronate-semialdehyde synthase activity
XI02_RS17740	COG3622	Belongs to the hyi family
XI02_RS17745	COG2084	Dehydrogenase
XI02_RS17750	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XI02_RS17765	COG1172	Belongs to the binding-protein-dependent transport system permease family
XI02_RS17770	COG1172	Belongs to the binding-protein-dependent transport system permease family
XI02_RS17775	COG1129	ABC transporter
XI02_RS17780	COG1879	ABC-type sugar transport system periplasmic component
XI02_RS17800	COG0583	DNA-binding transcription factor activity
XI02_RS17805	COG1984	allophanate hydrolase subunit 2
XI02_RS17815	COG0439	Biotin carboxylase
XI02_RS17825	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
XI02_RS17885	COG1172	Belongs to the binding-protein-dependent transport system permease family
XI02_RS17905	COG1129	ABC transporter
XI02_RS17915	COG0318	PFAM AMP-dependent synthetase and ligase
XI02_RS17935	COG3474	cytochrome
XI02_RS17985	COG3383	formate dehydrogenase (NAD+) activity
XI02_RS17990	COG0437	4 iron, 4 sulfur cluster binding
XI02_RS18025	COG0628	permease
XI02_RS18035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XI02_RS18045	COG4566	intracellular signal transduction
XI02_RS18110	COG3064	Membrane
XI02_RS18150	COG2985	domain, Protein
XI02_RS18155	COG2985	domain, Protein
XI02_RS18180	COG2963	transposase activity
XI02_RS18190	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
XI02_RS18205	COG1484	DNA-dependent DNA replication
XI02_RS18210	COG4584	PFAM Integrase catalytic
XI02_RS18295	COG1024	Enoyl-CoA hydratase
XI02_RS18300	COG1960	acyl-CoA dehydrogenase activity
XI02_RS18335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XI02_RS18355	COG1024	Enoyl-CoA hydratase
XI02_RS18355	COG1250	3-hydroxyacyl-CoA dehydrogenase
XI02_RS18370	COG1024	Enoyl-CoA hydratase
XI02_RS18380	COG1024	Enoyl-CoA hydratase
XI02_RS18390	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XI02_RS18405	COG0318	PFAM AMP-dependent synthetase and ligase
XI02_RS18420	COG1024	Enoyl-CoA hydratase
XI02_RS18450	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
XI02_RS18510	COG0583	DNA-binding transcription factor activity
XI02_RS18515	COG4948	Mandelate Racemase Muconate Lactonizing
XI02_RS18520	COG3485	protocatechuate 3,4-dioxygenase
XI02_RS18530	COG0196	riboflavin kinase activity
XI02_RS18555	COG2205	protein histidine kinase activity
XI02_RS18555	COG2202	Pas domain
XI02_RS18560	COG2084	Dehydrogenase
XI02_RS18570	COG0489	protein tyrosine kinase activity
XI02_RS18580	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
XI02_RS18585	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
XI02_RS18590	COG0745	RESPONSE REGULATOR receiver
XI02_RS18600	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
XI02_RS18605	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
XI02_RS18615	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XI02_RS18625	COG0546	phosphoglycolate phosphatase activity
XI02_RS18635	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
XI02_RS18665	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XI02_RS18670	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XI02_RS18690	COG0215	cysteine-tRNA ligase activity
XI02_RS18700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XI02_RS18715	COG5265	(ABC) transporter
XI02_RS18720	COG0688	phosphatidylethanolamine metabolic process
XI02_RS18735	COG0861	Integral membrane protein TerC family
XI02_RS18745	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS18760	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XI02_RS18770	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
XI02_RS18775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XI02_RS18785	COG0318	PFAM AMP-dependent synthetase and ligase
XI02_RS18800	COG2030	dehydratase
XI02_RS18810	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS18815	COG1960	acyl-CoA dehydrogenase activity
XI02_RS18820	COG0840	transmembrane signaling receptor activity
XI02_RS18825	COG0028	Belongs to the TPP enzyme family
XI02_RS18850	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XI02_RS18860	COG3158	transport of potassium into the cell
XI02_RS18865	COG3158	transport of potassium into the cell
XI02_RS18875	COG0436	Aminotransferase
XI02_RS18880	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
XI02_RS18890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XI02_RS18895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XI02_RS18900	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XI02_RS18905	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XI02_RS18920	COG1285	pathogenesis
XI02_RS18935	COG5001	Diguanylate cyclase
XI02_RS18955	COG3258	Cytochrome c
XI02_RS18965	COG0531	amino acid
XI02_RS18980	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XI02_RS19005	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XI02_RS19025	COG4774	siderophore transport
XI02_RS19030	COG3128	pkhd-type hydroxylase
XI02_RS19040	COG0848	biopolymer transport protein
XI02_RS19060	COG1994	Peptidase M50
XI02_RS19070	COG0583	DNA-binding transcription factor activity
XI02_RS19075	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS19080	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS19085	COG0129	dihydroxy-acid dehydratase activity
XI02_RS19090	COG1609	Transcriptional regulator
XI02_RS19095	COG3842	ATPase activity
XI02_RS19110	COG0395	ABC-type sugar transport system, permease component
XI02_RS19115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XI02_RS19120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XI02_RS19125	COG0800	Aldolase
XI02_RS19130	COG0183	Belongs to the thiolase family
XI02_RS19135	COG0318	PFAM AMP-dependent synthetase and ligase
XI02_RS19145	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XI02_RS19170	COG2066	Belongs to the glutaminase family
XI02_RS19170	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
XI02_RS19195	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XI02_RS19205	COG4689	acetoacetate decarboxylase
XI02_RS19220	COG2271	Major facilitator Superfamily
XI02_RS19225	COG0183	Belongs to the thiolase family
XI02_RS19245	COG3852	Histidine kinase
XI02_RS19250	COG1024	Enoyl-CoA hydratase
XI02_RS19275	COG1960	acyl-CoA dehydrogenase activity
XI02_RS19290	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XI02_RS19305	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS19310	COG0493	'glutamate synthase
XI02_RS19310	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
XI02_RS19315	COG2814	Major facilitator Superfamily
XI02_RS19320	COG0583	DNA-binding transcription factor activity
XI02_RS19330	COG0488	(ABC) transporter
XI02_RS19335	COG1671	Belongs to the UPF0178 family
XI02_RS19355	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XI02_RS19400	COG1022	Amp-dependent synthetase and ligase
XI02_RS19405	COG2130	NADP-dependent
XI02_RS19430	COG2814	Major facilitator Superfamily
XI02_RS19450	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XI02_RS19450	COG0519	Catalyzes the synthesis of GMP from XMP
XI02_RS19460	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
XI02_RS19490	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS19495	COG0583	DNA-binding transcription factor activity
XI02_RS19505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XI02_RS19515	COG0625	glutathione transferase activity
XI02_RS19530	COG0242	peptide deformylase activity
XI02_RS19540	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XI02_RS19565	COG0583	DNA-binding transcription factor activity
XI02_RS19580	COG0477	Major facilitator Superfamily
XI02_RS19590	COG0583	DNA-binding transcription factor activity
XI02_RS19595	COG2814	Major facilitator Superfamily
XI02_RS19605	COG1764	response to oxidative stress
XI02_RS19610	COG1846	Transcriptional regulator
XI02_RS19630	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XI02_RS19650	COG2814	Major facilitator Superfamily
XI02_RS19685	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
XI02_RS19710	COG1695	Transcriptional regulator
XI02_RS19720	COG0456	acetyltransferase
XI02_RS19750	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS19755	COG0625	glutathione transferase activity
XI02_RS19770	COG1301	dicarboxylic acid transport
XI02_RS19805	COG1393	Belongs to the ArsC family
XI02_RS19835	COG0559	Belongs to the binding-protein-dependent transport system permease family
XI02_RS19840	COG4214	carbohydrate transport
XI02_RS19845	COG1392	Phosphate transport regulator
XI02_RS19850	COG0306	phosphate transporter
XI02_RS19875	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XI02_RS19880	COG0318	PFAM AMP-dependent synthetase and ligase
XI02_RS19895	COG1160	GTP binding
XI02_RS19940	COG0300	oxidoreductase activity
XI02_RS19945	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
XI02_RS19950	COG1286	toxin biosynthetic process
XI02_RS19975	COG3385	transposase activity
XI02_RS19985	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XI02_RS19990	COG0305	Participates in initiation and elongation during chromosome replication
XI02_RS20000	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XI02_RS20020	COG0359	binds to the 23S rRNA
XI02_RS20030	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
XI02_RS20035	COG0360	Binds together with S18 to 16S ribosomal RNA
XI02_RS20050	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XI02_RS20065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XI02_RS20070	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XI02_RS20075	COG1561	YicC-like family, N-terminal region
XI02_RS20080	COG0194	GDP metabolic process
XI02_RS20100	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XI02_RS20105	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XI02_RS20115	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XI02_RS20125	COG0795	lipopolysaccharide-transporting ATPase activity
XI02_RS20130	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XI02_RS20135	COG2927	DNA polymerase III (CHI subunit)
XI02_RS20145	COG0488	(ABC) transporter
XI02_RS20160	COG0105	UTP biosynthetic process
XI02_RS20165	COG0861	Integral membrane protein TerC family
XI02_RS20175	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XI02_RS20185	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XI02_RS20190	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XI02_RS20195	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XI02_RS20200	COG1278	Cold shock
XI02_RS20205	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
XI02_RS20210	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XI02_RS20210	COG1672	PFAM Archaeal ATPase
XI02_RS20230	COG3685	Protein conserved in bacteria
XI02_RS20240	COG0583	DNA-binding transcription factor activity
XI02_RS20245	COG1063	alcohol dehydrogenase
XI02_RS20250	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
XI02_RS20255	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XI02_RS20265	COG0280	phosphate acetyltransferase
XI02_RS20265	COG0281	malic enzyme
XI02_RS20285	COG0386	Belongs to the glutathione peroxidase family
XI02_RS20295	COG3045	CreA protein
XI02_RS20335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XI02_RS20340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
XI02_RS20375	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS20390	COG2365	Tyrosine phosphatase family
XI02_RS20405	COG0174	glutamine synthetase
XI02_RS20460	COG0488	(ABC) transporter
XI02_RS20520	COG1960	acyl-CoA dehydrogenase activity
XI02_RS20535	COG0431	NADPH-dependent FMN reductase
XI02_RS20540	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS20550	COG1376	ErfK ybiS ycfS ynhG family protein
XI02_RS20560	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XI02_RS20570	COG2226	methyltransferase
XI02_RS20600	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XI02_RS20620	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XI02_RS20625	COG0583	DNA-binding transcription factor activity
XI02_RS20660	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XI02_RS20665	COG2824	Alkylphosphonate utilization operon protein PhnA
XI02_RS20670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XI02_RS20675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XI02_RS20710	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XI02_RS20715	COG0697	spore germination
XI02_RS20720	COG0784	Response regulator, receiver
XI02_RS20720	COG4191	Histidine kinase
XI02_RS20725	COG0745	RESPONSE REGULATOR receiver
XI02_RS20770	COG0657	acetylesterase activity
XI02_RS20785	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
XI02_RS20790	COG0471	metal ion transport
XI02_RS20795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XI02_RS20800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XI02_RS20830	COG4565	transcriptional regulatory protein
XI02_RS20835	COG0784	Response regulator, receiver
XI02_RS20840	COG5002	protein histidine kinase activity
XI02_RS20850	COG0511	ligase activity, forming carbon-carbon bonds
XI02_RS20855	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XI02_RS20880	COG0436	Aminotransferase
XI02_RS20885	COG1301	dicarboxylic acid transport
XI02_RS20895	COG1530	ribonuclease E activity
XI02_RS20895	COG1530	ribonuclease E activity
XI02_RS20900	COG0860	N-Acetylmuramoyl-L-alanine amidase
XI02_RS20905	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XI02_RS20915	COG2084	Dehydrogenase
XI02_RS20925	COG2192	nodulation
XI02_RS20940	COG0438	transferase activity, transferring glycosyl groups
XI02_RS20950	COG0438	transferase activity, transferring glycosyl groups
XI02_RS20975	COG0739	heme binding
XI02_RS21000	COG2271	Major facilitator Superfamily
XI02_RS21005	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XI02_RS21010	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
XI02_RS21015	COG0625	glutathione transferase activity
XI02_RS21025	COG2945	thiolester hydrolase activity
XI02_RS21035	COG0719	Fe-S assembly protein
XI02_RS21040	COG0396	ATPase activity
XI02_RS21045	COG0719	Fe-S assembly protein
XI02_RS21050	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XI02_RS21060	COG0316	Belongs to the HesB IscA family
XI02_RS21075	COG0513	Belongs to the DEAD box helicase family
XI02_RS21095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XI02_RS21100	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS21110	COG0187	DNA topoisomerase II activity
XI02_RS21120	COG0586	Pfam SNARE associated Golgi protein
XI02_RS21125	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XI02_RS21135	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
XI02_RS21155	COG3243	poly(R)-hydroxyalkanoic acid synthase
XI02_RS21165	COG0436	Aminotransferase
XI02_RS21175	COG1494	fructose-1,6-bisphosphatase
XI02_RS21190	COG2207	Transcriptional regulator
XI02_RS21195	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XI02_RS21215	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XI02_RS21225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XI02_RS21230	COG3152	Membrane
XI02_RS21245	COG1942	4-Oxalocrotonate Tautomerase
XI02_RS21255	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XI02_RS21280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XI02_RS21335	COG0625	glutathione transferase activity
XI02_RS21365	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XI02_RS21370	COG1278	Cold shock
XI02_RS21390	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
XI02_RS21400	COG2192	nodulation
XI02_RS21415	COG1522	sequence-specific DNA binding
XI02_RS21425	COG1960	acyl-CoA dehydrogenase activity
XI02_RS21430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XI02_RS21450	COG3706	GGDEF domain
XI02_RS21455	COG0129	dihydroxy-acid dehydratase activity
XI02_RS21460	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
XI02_RS21470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XI02_RS21475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XI02_RS21485	COG0232	Belongs to the dGTPase family. Type 2 subfamily
XI02_RS21490	COG0018	arginyl-trna synthetase
XI02_RS21500	COG1472	Belongs to the glycosyl hydrolase 3 family
XI02_RS21505	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XI02_RS21510	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XI02_RS21515	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XI02_RS21520	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XI02_RS21525	COG0805	protein transport
XI02_RS21530	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XI02_RS21540	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XI02_RS21550	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XI02_RS21555	COG4942	peptidase
XI02_RS21565	COG1862	Preprotein translocase
XI02_RS21570	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XI02_RS21600	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
XI02_RS21705	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XI02_RS21720	COG0629	single-stranded DNA binding
XI02_RS21730	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
XI02_RS21740	COG3158	transport of potassium into the cell
XI02_RS21750	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XI02_RS21770	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XI02_RS21775	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XI02_RS21785	COG1309	transcriptional regulator
XI02_RS21795	COG0343	queuine tRNA-ribosyltransferase activity
XI02_RS21815	COG0697	spore germination
XI02_RS21820	COG0251	oxidation-reduction process
XI02_RS21835	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XI02_RS21840	COG1253	flavin adenine dinucleotide binding
XI02_RS21860	COG1250	3-hydroxyacyl-CoA dehydrogenase
XI02_RS21890	COG1234	tRNA 3'-trailer cleavage
XI02_RS21980	COG1802	Transcriptional regulator
XI02_RS21980	COG4626	Terminase
XI02_RS22005	COG1432	Conserved Protein
XI02_RS22030	COG1484	DNA-dependent DNA replication
XI02_RS22035	COG4584	PFAM Integrase catalytic
XI02_RS22075	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XI02_RS22080	COG3547	Transposase (IS116 IS110 IS902 family)
XI02_RS22085	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XI02_RS22110	COG4716	Myosin-crossreactive antigen
XI02_RS22125	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XI02_RS22145	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XI02_RS22155	COG1126	abc transporter atp-binding protein
XI02_RS22160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XI02_RS22165	COG0765	amino acid transport
XI02_RS22170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XI02_RS22200	COG2814	Major facilitator Superfamily
XI02_RS22210	COG0679	Auxin Efflux Carrier
XI02_RS22215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XI02_RS22220	COG1183	phosphatidylcholine synthase activity
XI02_RS22225	COG1253	flavin adenine dinucleotide binding
XI02_RS22235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XI02_RS22250	COG0071	Belongs to the small heat shock protein (HSP20) family
XI02_RS22260	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XI02_RS22265	COG3707	response regulator
XI02_RS22270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XI02_RS22270	COG1116	anion transmembrane transporter activity
XI02_RS22285	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
XI02_RS22290	COG1984	allophanate hydrolase subunit 2
XI02_RS22295	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
XI02_RS22300	COG0473	3-isopropylmalate dehydrogenase activity
XI02_RS22300	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XI02_RS22325	COG0154	amidase activity
XI02_RS22340	COG0395	ABC-type sugar transport system, permease component
XI02_RS22345	COG1175	transmembrane transport
XI02_RS22360	COG0346	lactoylglutathione lyase activity
XI02_RS22365	COG1960	acyl-CoA dehydrogenase activity
XI02_RS22370	COG0477	Major facilitator Superfamily
XI02_RS22385	COG0210	DNA helicase
XI02_RS22415	COG0784	Response regulator, receiver
XI02_RS22415	COG4191	Histidine kinase
XI02_RS22435	COG2814	Major facilitator Superfamily
XI02_RS22465	COG0596	Alpha beta hydrolase
XI02_RS22550	COG2217	Heavy metal translocating P-type atpase
XI02_RS22555	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
XI02_RS22560	COG1136	(ABC) transporter
XI02_RS22600	COG5549	protein import
XI02_RS22600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XI02_RS22610	COG2267	carboxylic ester hydrolase activity
XI02_RS22615	COG1686	Belongs to the peptidase S11 family
XI02_RS22620	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XI02_RS22635	COG0084	hydrolase, TatD family'
XI02_RS22640	COG0321	lipoyl(octanoyl) transferase activity
XI02_RS22640	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
XI02_RS22645	COG0318	PFAM AMP-dependent synthetase and ligase
XI02_RS22655	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XI02_RS22660	COG1335	isochorismatase
XI02_RS22665	COG3237	CsbD-like
XI02_RS22670	COG3685	Protein conserved in bacteria
XI02_RS22680	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
XI02_RS22770	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
XI02_RS22780	COG1024	Enoyl-CoA hydratase
XI02_RS22800	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
XI02_RS22805	COG3956	TIGRFAM MazG family protein
XI02_RS22810	COG2239	Acts as a magnesium transporter
XI02_RS22815	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XI02_RS22820	COG1923	regulation of RNA biosynthetic process
XI02_RS22825	COG2204	response regulator
XI02_RS22830	COG5000	phosphorelay sensor kinase activity
XI02_RS22850	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XI02_RS22850	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
XI02_RS22855	COG1546	Belongs to the CinA family
XI02_RS22855	COG1058	Belongs to the CinA family
XI02_RS22865	COG2867	negative regulation of translational initiation
XI02_RS22875	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XI02_RS22880	COG2094	Belongs to the DNA glycosylase MPG family
XI02_RS22885	COG0525	valine-tRNA ligase activity
XI02_RS22900	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XI02_RS22950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XI02_RS22960	COG1538	Outer membrane efflux protein
XI02_RS22965	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
XI02_RS22970	COG1126	abc transporter atp-binding protein
XI02_RS22975	COG0765	amino acid transport
XI02_RS22980	COG4597	amino acid ABC transporter
XI02_RS22985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XI02_RS22990	COG0626	cystathionine gamma-synthase activity
XI02_RS23000	COG4964	Belongs to the GSP D family
XI02_RS23040	COG0463	Glycosyl transferase, family 2
XI02_RS23055	COG4953	penicillin-binding protein 1C
XI02_RS23060	COG2373	Large extracellular alpha-helical protein
XI02_RS23125	COG0800	Aldolase
XI02_RS23130	COG3734	2-keto-3-deoxy-galactonokinase
XI02_RS23170	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XI02_RS23210	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
XI02_RS23215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XI02_RS23230	COG0508	dehydrogenase complex catalyzes the overall conversion of
XI02_RS23240	COG0508	dehydrogenase complex catalyzes the overall conversion of
XI02_RS23240	COG0022	dehydrogenase e1 component
XI02_RS23245	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XI02_RS23255	COG0431	NADPH-dependent FMN reductase
XI02_RS23260	COG1063	alcohol dehydrogenase
XI02_RS23265	COG0148	phosphopyruvate hydratase activity
XI02_RS23275	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XI02_RS23285	COG2814	Major facilitator Superfamily
XI02_RS23290	COG2877	3-deoxy-8-phosphooctulonate synthase activity
XI02_RS23305	COG0745	RESPONSE REGULATOR receiver
XI02_RS23310	COG2205	protein histidine kinase activity
XI02_RS23320	COG0504	CTP synthase activity
XI02_RS23330	COG1396	sequence-specific DNA binding
XI02_RS23340	COG0149	triose-phosphate isomerase activity
XI02_RS23345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XI02_RS23350	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XI02_RS23355	COG0134	indole-3-glycerol-phosphate synthase activity
XI02_RS23360	COG0315	cyclic pyranopterin monophosphate synthase activity
XI02_RS23365	COG5001	Diguanylate cyclase
XI02_RS23370	COG0793	Belongs to the peptidase S41A family
XI02_RS23375	COG1902	pentaerythritol trinitrate reductase activity
XI02_RS23390	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XI02_RS23395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XI02_RS23410	COG2197	response regulator
XI02_RS23415	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XI02_RS23430	COG1011	Hydrolase
XI02_RS23435	COG0303	'Molybdopterin
XI02_RS23440	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XI02_RS23460	COG0477	Major facilitator Superfamily
XI02_RS23485	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XI02_RS23490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XI02_RS23495	COG0372	Belongs to the citrate synthase family
XI02_RS23500	COG0640	Transcriptional regulator
XI02_RS23510	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XI02_RS23520	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XI02_RS23530	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XI02_RS23535	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XI02_RS23540	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XI02_RS23550	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XI02_RS23560	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XI02_RS23565	COG0233	cytoplasmic translational termination
XI02_RS23570	COG0528	UMP kinase activity
XI02_RS23575	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XI02_RS23580	COG0052	Belongs to the universal ribosomal protein uS2 family
XI02_RS23605	COG1136	(ABC) transporter
XI02_RS23615	COG0442	prolyl-tRNA aminoacylation
XI02_RS23645	COG4774	siderophore transport
XI02_RS23665	COG1129	ABC transporter
XI02_RS23670	COG1172	Belongs to the binding-protein-dependent transport system permease family
XI02_RS23685	COG0346	lactoylglutathione lyase activity
XI02_RS23700	COG1007	ATP synthesis coupled electron transport
XI02_RS23715	COG0713	ATP synthesis coupled electron transport
XI02_RS23725	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XI02_RS23730	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XI02_RS23745	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XI02_RS23755	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XI02_RS23760	COG0649	NAD binding
XI02_RS23770	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XI02_RS23805	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XI02_RS23805	COG0546	phosphoglycolate phosphatase activity
XI02_RS23830	COG0776	regulation of translation
XI02_RS23835	COG2195	Cleaves the N-terminal amino acid of tripeptides
XI02_RS23840	COG2226	methyltransferase
XI02_RS23880	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
XI02_RS23885	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XI02_RS23890	COG0740	serine-type endopeptidase activity
XI02_RS23895	COG0544	peptidyl-prolyl cis-trans isomerase activity
XI02_RS23925	COG2814	Major facilitator Superfamily
XI02_RS23935	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XI02_RS23940	COG2301	Belongs to the HpcH HpaI aldolase family
XI02_RS23945	COG0583	DNA-binding transcription factor activity
XI02_RS23950	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XI02_RS23960	COG1032	radical SAM domain protein
XI02_RS23970	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XI02_RS23970	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XI02_RS23975	COG0347	Belongs to the P(II) protein family
XI02_RS23980	COG0174	glutamine synthetase
XI02_RS23995	COG4191	Histidine kinase
XI02_RS23995	COG0784	Response regulator, receiver
XI02_RS24005	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XI02_RS24025	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XI02_RS24030	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
XI02_RS24040	COG1024	Enoyl-CoA hydratase
XI02_RS24065	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
XI02_RS24070	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
XI02_RS24080	COG1612	heme a metabolic process
XI02_RS24110	COG0583	DNA-binding transcription factor activity
XI02_RS24125	COG1596	polysaccharide export
XI02_RS24130	COG0438	transferase activity, transferring glycosyl groups
XI02_RS24145	COG1846	Transcriptional regulator
XI02_RS24150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XI02_RS24155	COG3268	Saccharopine dehydrogenase
XI02_RS24175	COG0318	PFAM AMP-dependent synthetase and ligase
XI02_RS24315	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XI02_RS24320	COG1061	Type III restriction enzyme res subunit
XI02_RS24325	COG1002	Type II restriction enzyme, methylase subunits
XI02_RS24545	COG3118	belongs to the thioredoxin family
XI02_RS24980	COG0629	single-stranded DNA binding
XI02_RS25000	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XI02_RS25010	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XI02_RS25080	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XI02_RS25145	COG0776	regulation of translation
XI02_RS25150	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XI02_RS25155	COG0416	fatty acid biosynthetic process
XI02_RS25185	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XI02_RS25190	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XI02_RS25195	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XI02_RS25200	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XI02_RS25210	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XI02_RS25210	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XI02_RS25215	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XI02_RS25220	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XI02_RS25225	COG4774	siderophore transport
XI02_RS25280	COG0113	porphobilinogen synthase activity
XI02_RS25290	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
XI02_RS25295	COG1914	H( )-stimulated, divalent metal cation uptake system
XI02_RS25310	COG2268	Band 7 protein
XI02_RS25340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XI02_RS25350	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
XI02_RS25355	COG1381	Involved in DNA repair and RecF pathway recombination
XI02_RS25365	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XI02_RS25370	COG0571	ribonuclease III activity
XI02_RS25375	COG0681	Belongs to the peptidase S26 family
XI02_RS25380	COG0736	holo-[acyl-carrier-protein] synthase activity
XI02_RS25385	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XI02_RS25395	COG1758	RNA polymerase activity
XI02_RS25415	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XI02_RS25420	COG1970	mechanosensitive ion channel activity
XI02_RS25425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XI02_RS25430	COG0741	lytic transglycosylase activity
XI02_RS25465	COG0583	DNA-binding transcription factor activity
XI02_RS25475	COG2223	nitrite transmembrane transporter activity
XI02_RS25495	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
XI02_RS25510	COG0154	amidase activity
XI02_RS25520	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
XI02_RS25525	COG2070	2-Nitropropane dioxygenase
XI02_RS25530	COG2070	2-Nitropropane dioxygenase
XI02_RS25535	COG0583	DNA-binding transcription factor activity
XI02_RS25545	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XI02_RS25575	COG1960	acyl-CoA dehydrogenase activity
XI02_RS25590	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XI02_RS25595	COG0540	Belongs to the ATCase OTCase family
XI02_RS25600	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XI02_RS25605	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
XI02_RS25610	COG0154	amidase activity
XI02_RS25615	COG0758	DNA mediated transformation
XI02_RS25620	COG1733	regulation of RNA biosynthetic process
XI02_RS25625	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XI02_RS25635	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS25650	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XI02_RS25655	COG0557	exoribonuclease II activity
XI02_RS25675	COG0267	Belongs to the bacterial ribosomal protein bL33 family
XI02_RS25690	COG0004	ammonium transporteR
XI02_RS25700	COG1309	transcriptional regulator
XI02_RS25715	COG0784	Response regulator, receiver
XI02_RS25725	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XI02_RS25755	COG0537	adenosine 5'-monophosphoramidase activity
XI02_RS25760	COG1720	tRNA m6t6A37 methyltransferase activity
XI02_RS25805	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XI02_RS25820	COG2814	Major facilitator Superfamily
XI02_RS25830	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
XI02_RS25845	COG1686	Belongs to the peptidase S11 family
XI02_RS25870	COG1192	Involved in chromosome partitioning
XI02_RS25875	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XI02_RS25905	COG0625	glutathione transferase activity
XI02_RS25920	COG0656	L-ascorbic acid biosynthetic process
XI02_RS25930	COG3511	phospholipase C
XI02_RS25955	COG1802	Transcriptional regulator
XI02_RS25965	COG2271	Major facilitator Superfamily
XI02_RS25970	COG2271	Major facilitator Superfamily
XI02_RS25975	COG1012	belongs to the aldehyde dehydrogenase family
XI02_RS25990	COG0583	DNA-binding transcription factor activity
XI02_RS26020	COG0798	PFAM Bile acid sodium symporter
XI02_RS26035	COG2239	Acts as a magnesium transporter
XI02_RS26045	COG0726	polysaccharide deacetylase
XI02_RS26065	COG0321	lipoyl(octanoyl) transferase activity
XI02_RS26090	COG1090	epimerase
XI02_RS26105	COG2226	methyltransferase
XI02_RS26110	COG1254	Belongs to the acylphosphatase family
XI02_RS26115	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
XI02_RS26120	COG4770	biotin carboxylase activity
XI02_RS26150	COG5001	Diguanylate cyclase
XI02_RS26185	COG0450	alkyl hydroperoxide reductase
XI02_RS26190	COG0415	Belongs to the DNA photolyase family
XI02_RS26195	COG0697	spore germination
XI02_RS26220	COG2807	transmembrane transport
XI02_RS26225	COG2207	Transcriptional regulator
XI02_RS26245	COG0475	glutathione-regulated potassium exporter activity
XI02_RS26300	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XI02_RS26355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XI02_RS26360	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS26365	COG2030	dehydratase
XI02_RS26390	COG2010	Cytochrome c
XI02_RS26390	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XI02_RS26395	COG2860	membrane
XI02_RS26460	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XI02_RS26475	COG0697	spore germination
XI02_RS26480	COG0436	Aminotransferase
XI02_RS26495	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XI02_RS26530	COG2066	Belongs to the glutaminase family
XI02_RS26545	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
XI02_RS26560	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XI02_RS26565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XI02_RS26570	COG3746	phosphate-selective porin O and P
XI02_RS26575	COG1733	regulation of RNA biosynthetic process
XI02_RS26600	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS26605	COG0203	ribosomal protein L17
XI02_RS26610	COG0202	RNA polymerase activity
XI02_RS26615	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
XI02_RS26620	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
XI02_RS26625	COG0563	adenylate kinase activity
XI02_RS26635	COG0200	Binds to the 23S rRNA
XI02_RS26640	COG1841	ribosomal large subunit assembly
XI02_RS26645	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
XI02_RS26650	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
XI02_RS26655	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
XI02_RS26660	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
XI02_RS26665	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
XI02_RS26670	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XI02_RS26675	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XI02_RS26680	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
XI02_RS26685	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XI02_RS26690	COG0255	Belongs to the universal ribosomal protein uL29 family
XI02_RS26695	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XI02_RS26700	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
XI02_RS26705	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
XI02_RS26710	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
XI02_RS26715	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XI02_RS26720	COG0089	rRNA binding
XI02_RS26725	COG0088	Forms part of the polypeptide exit tunnel
XI02_RS26730	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
XI02_RS26735	COG0051	transcription antitermination factor activity, RNA binding
XI02_RS26740	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XI02_RS26745	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XI02_RS26750	COG0049	tRNA binding
XI02_RS26755	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XI02_RS26765	COG1132	(ABC) transporter
XI02_RS26770	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
XI02_RS26775	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XI02_RS26780	COG0085	RNA polymerase activity
XI02_RS26790	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XI02_RS26800	COG1595	DNA-templated transcription, initiation
XI02_RS26805	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XI02_RS26810	COG0081	regulation of translation
XI02_RS26815	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XI02_RS26820	COG0250	Participates in transcription elongation, termination and antitermination
XI02_RS26825	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XI02_RS26830	COG2205	protein histidine kinase activity
XI02_RS26845	COG0318	PFAM AMP-dependent synthetase and ligase
XI02_RS26850	COG2186	Transcriptional regulator
XI02_RS26880	COG3246	L-lysine catabolic process to acetate
XI02_RS26905	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS26920	COG3547	Transposase (IS116 IS110 IS902 family)
XI02_RS26945	COG1960	acyl-CoA dehydrogenase activity
XI02_RS26955	COG0251	oxidation-reduction process
XI02_RS26960	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XI02_RS26980	COG0243	molybdopterin cofactor binding
XI02_RS26985	COG2146	nitrite reductase [NAD(P)H] activity
XI02_RS26990	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XI02_RS27000	COG2223	nitrite transmembrane transporter activity
XI02_RS27005	COG2815	serine threonine protein kinase
XI02_RS27005	COG0515	serine threonine protein kinase
XI02_RS27080	COG2815	serine threonine protein kinase
XI02_RS27080	COG0515	serine threonine protein kinase
XI02_RS27165	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XI02_RS27165	COG4797	methyltransferase
XI02_RS27190	COG2376	Dihydroxyacetone kinase
XI02_RS27200	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XI02_RS27210	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
XI02_RS27215	COG1461	Dihydroxyacetone kinase
XI02_RS27220	COG3842	ATPase activity
XI02_RS27225	COG3842	ATPase activity
XI02_RS27235	COG0395	ABC-type sugar transport system, permease component
XI02_RS27240	COG1175	transmembrane transport
XI02_RS27280	COG3795	YCII-related domain
XI02_RS27335	COG0402	S-adenosylhomocysteine deaminase activity
XI02_RS27340	COG0477	Major facilitator Superfamily
XI02_RS27365	COG0583	DNA-binding transcription factor activity
XI02_RS27370	COG3665	Urea carboxylase-associated protein
XI02_RS27395	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XI02_RS27455	COG0596	Alpha beta hydrolase
XI02_RS27555	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XI02_RS27575	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XI02_RS27585	COG0583	DNA-binding transcription factor activity
XI02_RS27595	COG0109	protoheme IX farnesyltransferase activity
XI02_RS27615	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XI02_RS27620	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XI02_RS27635	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XI02_RS27665	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XI02_RS27670	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XI02_RS27690	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XI02_RS27695	COG0302	gtp cyclohydrolase
XI02_RS27710	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
XI02_RS27720	COG2814	Major facilitator Superfamily
XI02_RS27730	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XI02_RS27740	COG5001	Diguanylate cyclase
XI02_RS27750	COG1752	Esterase of the alpha-beta hydrolase superfamily
XI02_RS27755	COG0517	IMP dehydrogenase activity
XI02_RS27770	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XI02_RS27790	COG1982	Orn Lys Arg decarboxylase major
XI02_RS27800	COG3360	Dodecin
XI02_RS27820	COG2423	ornithine cyclodeaminase activity
XI02_RS27840	COG0747	negative chemotaxis
XI02_RS27875	COG0527	aspartate kinase activity
XI02_RS27885	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
XI02_RS27890	COG3964	amidohydrolase
XI02_RS27900	COG1063	alcohol dehydrogenase
XI02_RS27925	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XI02_RS27985	COG2267	carboxylic ester hydrolase activity
XI02_RS28000	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XI02_RS28020	COG0747	negative chemotaxis
XI02_RS28035	COG0601	transmembrane transport
XI02_RS28040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XI02_RS28045	COG4172	Belongs to the ABC transporter superfamily
XI02_RS28055	COG1473	amidohydrolase
XI02_RS28060	COG0154	amidase activity
XI02_RS28065	COG1024	Enoyl-CoA hydratase
XI02_RS28090	COG0625	glutathione transferase activity
XI02_RS28095	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
XI02_RS28105	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
XI02_RS28110	COG1058	Belongs to the CinA family
XI02_RS28110	COG1546	Belongs to the CinA family
XI02_RS28115	COG2308	Evidence 4 Homologs of previously reported genes of
XI02_RS28140	COG0022	dehydrogenase e1 component
XI02_RS28145	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XI02_RS28170	COG4221	oxidoreductase activity
XI02_RS28180	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XI02_RS28210	COG5425	PFAM Usg family protein
XI02_RS28215	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XI02_RS28220	COG0459	protein refolding
XI02_RS28240	COG1672	PFAM Archaeal ATPase
XI02_RS28240	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XI02_RS28250	COG1335	isochorismatase
XI02_RS28255	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
XI02_RS28265	COG1012	belongs to the aldehyde dehydrogenase family
XI02_RS28315	COG0384	phenazine biosynthesis protein PhzF
XI02_RS28325	COG0842	Transport permease protein
XI02_RS28330	COG1131	(ABC) transporter
XI02_RS28335	COG1566	PFAM secretion protein HlyD family protein
XI02_RS28340	COG1309	transcriptional regulator
XI02_RS28365	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XI02_RS28370	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XI02_RS28370	COG3608	succinylglutamate desuccinylase aspartoacylase
XI02_RS28405	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
XI02_RS28410	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XI02_RS28415	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XI02_RS28450	COG2852	Protein conserved in bacteria
XI02_RS28465	COG3191	aminopeptidase activity
XI02_RS28490	COG1309	transcriptional regulator
XI02_RS28510	COG3851	Histidine kinase
XI02_RS28520	COG1473	amidohydrolase
XI02_RS28525	COG2957	Belongs to the agmatine deiminase family
XI02_RS28535	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
XI02_RS28555	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
XI02_RS28585	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XI02_RS28595	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XI02_RS28600	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
XI02_RS28635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XI02_RS28640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XI02_RS28655	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XI02_RS28675	COG3181	Tripartite tricarboxylate transporter family receptor
XI02_RS28680	COG0047	phosphoribosylformylglycinamidine synthase activity
XI02_RS28690	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XI02_RS28695	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XI02_RS28715	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
XI02_RS28720	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
XI02_RS28725	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XI02_RS28725	COG1116	anion transmembrane transporter activity
XI02_RS28730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XI02_RS28735	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XI02_RS28790	COG2226	methyltransferase
XI02_RS28795	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
XI02_RS28805	COG0538	isocitrate dehydrogenase activity
XI02_RS28815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XI02_RS28820	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XI02_RS28825	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XI02_RS28830	COG0509	glycine decarboxylation via glycine cleavage system
XI02_RS28835	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XI02_RS28835	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XI02_RS28850	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XI02_RS28920	COG4993	Dehydrogenase
XI02_RS28980	COG1959	2 iron, 2 sulfur cluster binding
XI02_RS29015	COG2917	probably involved in intracellular septation
XI02_RS29035	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
XI02_RS29035	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
XI02_RS29050	COG3832	glyoxalase III activity
XI02_RS29055	COG0640	Transcriptional regulator
XI02_RS29095	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XI02_RS29100	COG1684	flagellar biosynthetic protein fliR
XI02_RS29105	COG1987	bacterial-type flagellum assembly
XI02_RS29110	COG1677	Flagellar hook-basal body complex protein FliE
XI02_RS29115	COG1558	bacterial-type flagellum-dependent cell motility
XI02_RS29130	COG1338	Plays a role in the flagellum-specific transport system
XI02_RS29160	COG1942	4-Oxalocrotonate Tautomerase
XI02_RS29165	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS29225	COG4786	Flagellar basal body rod
XI02_RS29230	COG4786	Flagellar basal body rod
XI02_RS29240	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
XI02_RS29315	COG1733	regulation of RNA biosynthetic process
XI02_RS29325	COG1706	bacterial-type flagellum-dependent cell motility
XI02_RS29360	COG5443	negative regulation of bacterial-type flagellum assembly
XI02_RS29375	COG1749	Flagellar hook protein flgE
XI02_RS29380	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XI02_RS29385	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
XI02_RS29385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XI02_RS29410	COG3181	Tripartite tricarboxylate transporter family receptor
XI02_RS29420	COG3300	MHYT domain
XI02_RS29420	COG5001	Diguanylate cyclase
XI02_RS29430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XI02_RS29445	COG5001	Diguanylate cyclase
XI02_RS29445	COG3300	MHYT domain
XI02_RS29455	COG0392	lysyltransferase activity
XI02_RS29475	COG0492	ferredoxin-NADP+ reductase activity
XI02_RS29485	COG0633	Ferredoxin
XI02_RS29500	COG3218	ABC-type transport auxiliary lipoprotein component
XI02_RS29500	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XI02_RS29510	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XI02_RS29515	COG4948	Mandelate Racemase Muconate Lactonizing
XI02_RS29520	COG2814	Major facilitator Superfamily
XI02_RS29535	COG0438	transferase activity, transferring glycosyl groups
XI02_RS29545	COG0351	phosphomethylpyrimidine kinase
XI02_RS29555	COG2010	Cytochrome c
XI02_RS29565	COG3909	cytochrome
XI02_RS29575	COG0728	peptidoglycan biosynthetic process
XI02_RS29585	COG0673	inositol 2-dehydrogenase activity
XI02_RS29590	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XI02_RS29590	COG0662	Cupin 2, conserved barrel domain protein
XI02_RS29600	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XI02_RS29605	COG0702	epimerase
XI02_RS29625	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
XI02_RS29625	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
XI02_RS29635	COG0859	PFAM glycosyl transferase family 9
XI02_RS29650	COG1132	(ABC) transporter
XI02_RS29700	COG1053	succinate dehydrogenase
XI02_RS29705	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS29710	COG1414	Transcriptional regulator
XI02_RS29720	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
XI02_RS29725	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XI02_RS29740	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
XI02_RS29790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XI02_RS29810	COG1022	Amp-dependent synthetase and ligase
XI02_RS29815	COG0559	Belongs to the binding-protein-dependent transport system permease family
XI02_RS29835	COG2942	2-epimerase
XI02_RS29840	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
XI02_RS29845	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XI02_RS29855	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XI02_RS29875	COG0367	asparagine synthase
XI02_RS29880	COG0438	transferase activity, transferring glycosyl groups
XI02_RS29890	COG0438	transferase activity, transferring glycosyl groups
XI02_RS29895	COG0438	transferase activity, transferring glycosyl groups
XI02_RS29945	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XI02_RS29965	COG0367	asparagine synthase
XI02_RS29985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XI02_RS30020	COG3436	PFAM IS66 Orf2 family protein
XI02_RS30025	COG2963	transposase activity
XI02_RS30035	COG3436	PFAM IS66 Orf2 family protein
XI02_RS30080	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
XI02_RS30085	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XI02_RS30090	COG3181	Tripartite tricarboxylate transporter family receptor
XI02_RS30095	COG1024	Enoyl-CoA hydratase
XI02_RS30100	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XI02_RS30105	COG2271	Major facilitator Superfamily
XI02_RS30110	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XI02_RS30120	COG0277	FAD linked oxidase domain protein
XI02_RS30120	COG0247	lactate metabolic process
XI02_RS30160	COG2948	multi-organism process
XI02_RS30190	COG3451	type IV secretory pathway VirB4
XI02_RS30200	COG3838	Conjugal transfer protein Trbc
XI02_RS30205	COG4962	Type ii secretion system protein e
XI02_RS30235	COG0681	Belongs to the peptidase S26 family
XI02_RS30290	COG5489	Protein of unknown function (DUF736)
XI02_RS30305	COG4974	Belongs to the 'phage' integrase family
XI02_RS30310	COG0582	viral genome integration into host DNA
XI02_RS30315	COG4974	Belongs to the 'phage' integrase family
XI02_RS30330	COG1024	Enoyl-CoA hydratase
XI02_RS30335	COG0243	molybdopterin cofactor binding
XI02_RS30430	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XI02_RS30445	COG0071	Belongs to the small heat shock protein (HSP20) family
XI02_RS30455	COG0459	protein refolding
XI02_RS30460	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XI02_RS30465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XI02_RS30475	COG3920	Histidine kinase
XI02_RS30510	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
XI02_RS30515	COG3842	ATPase activity
XI02_RS30525	COG4149	molybdate abc transporter
XI02_RS30535	COG1063	alcohol dehydrogenase
XI02_RS30595	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XI02_RS30635	COG1304	FMN binding
XI02_RS30640	COG4977	sequence-specific DNA binding
XI02_RS30650	COG2271	Major facilitator Superfamily
XI02_RS30655	COG3403	YqcI/YcgG family
XI02_RS30670	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XI02_RS30745	COG1024	Enoyl-CoA hydratase
XI02_RS30750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XI02_RS30765	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS30790	COG1309	transcriptional regulator
XI02_RS30800	COG2072	flavoprotein involved in K transport
XI02_RS30835	COG0628	permease
XI02_RS30845	COG0596	Alpha beta hydrolase
XI02_RS30860	COG3791	Glutathione-dependent formaldehyde-activating
XI02_RS30865	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
XI02_RS30900	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
XI02_RS30920	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XI02_RS30965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XI02_RS30975	COG1116	anion transmembrane transporter activity
XI02_RS31045	COG1749	Flagellar hook protein flgE
XI02_RS31065	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
XI02_RS31075	COG1595	DNA-templated transcription, initiation
XI02_RS31100	COG2031	fatty acid transporter
XI02_RS31105	COG0243	molybdopterin cofactor binding
XI02_RS31115	COG1960	acyl-CoA dehydrogenase activity
XI02_RS31120	COG1024	Enoyl-CoA hydratase
XI02_RS31130	COG0183	Belongs to the thiolase family
XI02_RS31150	COG1301	dicarboxylic acid transport
XI02_RS31155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XI02_RS31180	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
XI02_RS31185	COG1349	DNA-binding transcription factor activity
XI02_RS31195	COG0483	inositol monophosphate 1-phosphatase activity
XI02_RS31205	COG3178	'Phosphotransferase
XI02_RS31210	COG0154	amidase activity
XI02_RS31230	COG0747	negative chemotaxis
XI02_RS31235	COG0647	UMP catabolic process
XI02_RS31285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XI02_RS31290	COG2171	N-acyltransferase activity
XI02_RS31295	COG3383	formate dehydrogenase (NAD+) activity
XI02_RS31300	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XI02_RS31305	COG0303	'Molybdopterin
XI02_RS31315	COG0746	molybdenum cofactor guanylyltransferase activity
XI02_RS31320	COG0583	DNA-binding transcription factor activity
XI02_RS31325	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XI02_RS31330	COG2326	polyphosphate kinase activity
XI02_RS31390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XI02_RS31400	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XI02_RS31420	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS31440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XI02_RS31470	COG0517	IMP dehydrogenase activity
XI02_RS31470	COG1125	glycine betaine transport
XI02_RS31475	COG1174	glycine betaine transport
XI02_RS31485	COG1131	(ABC) transporter
XI02_RS31520	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XI02_RS31530	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XI02_RS31545	COG2264	protein methyltransferase activity
XI02_RS31550	COG0440	acetolactate synthase activity
XI02_RS31560	COG0028	Belongs to the TPP enzyme family
XI02_RS31565	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XI02_RS31570	COG0560	Phosphoserine phosphatase
XI02_RS31575	COG3547	Transposase (IS116 IS110 IS902 family)
XI02_RS31590	COG0330	HflC and HflK could
XI02_RS31595	COG0330	HflC and HflK could
XI02_RS31610	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
XI02_RS31650	COG0114	fumarate hydratase activity
XI02_RS31675	COG2124	cytochrome p450
XI02_RS31680	COG1309	transcriptional regulator
XI02_RS31685	COG2271	Major facilitator Superfamily
XI02_RS31700	COG1672	PFAM Archaeal ATPase
XI02_RS31700	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XI02_RS31705	COG0410	ABC transporter
XI02_RS31735	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XI02_RS31740	COG2186	Transcriptional regulator
XI02_RS31745	COG0785	Cytochrome C biogenesis protein
XI02_RS31765	COG0277	FAD linked oxidase domain protein
XI02_RS31775	COG5487	UPF0391 membrane protein
XI02_RS31780	COG0210	DNA helicase
XI02_RS31795	COG1131	(ABC) transporter
XI02_RS31800	COG0842	Transport permease protein
XI02_RS31845	COG2264	protein methyltransferase activity
XI02_RS31860	COG0006	proline dipeptidase activity
XI02_RS31865	COG2814	Major facilitator Superfamily
XI02_RS31870	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XI02_RS31880	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XI02_RS31890	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
XI02_RS31895	COG0849	cell division
XI02_RS31900	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XI02_RS31905	COG1181	Belongs to the D-alanine--D-alanine ligase family
XI02_RS31910	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XI02_RS31920	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XI02_RS31925	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XI02_RS31935	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
XI02_RS31940	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XI02_RS31950	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XI02_RS31965	COG0275	rRNA processing
XI02_RS31970	COG3023	N-Acetylmuramoyl-L-alanine amidase
XI02_RS31980	COG4941	Belongs to the sigma-70 factor family
XI02_RS31985	COG3795	YCII-related domain
XI02_RS32000	COG4191	Histidine kinase
XI02_RS32005	COG0583	DNA-binding transcription factor activity
XI02_RS32015	COG2610	gluconate transmembrane transporter activity
XI02_RS32040	COG0596	Alpha beta hydrolase
XI02_RS32050	COG5265	(ABC) transporter
XI02_RS32055	COG1943	Transposase
XI02_RS32070	COG1309	transcriptional regulator
XI02_RS32080	COG2072	flavoprotein involved in K transport
XI02_RS32085	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS32115	COG2917	probably involved in intracellular septation
XI02_RS32145	COG0745	RESPONSE REGULATOR receiver
XI02_RS32155	COG0688	phosphatidylethanolamine metabolic process
XI02_RS32160	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XI02_RS32175	COG0438	transferase activity, transferring glycosyl groups
XI02_RS32195	COG1376	ErfK ybiS ycfS ynhG family protein
XI02_RS32260	COG2022	thiamine diphosphate biosynthetic process
XI02_RS32270	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
XI02_RS32305	COG2391	methyltransferase activity
XI02_RS32315	COG2135	peptidase activity
XI02_RS32325	COG2816	NAD+ diphosphatase activity
XI02_RS32345	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XI02_RS32350	COG0354	folic acid binding
XI02_RS32355	COG0519	Catalyzes the synthesis of GMP from XMP
XI02_RS32360	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
XI02_RS32385	COG0604	alcohol dehydrogenase
XI02_RS32400	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XI02_RS32400	COG0574	Belongs to the PEP-utilizing enzyme family
XI02_RS32425	COG0751	glycine-tRNA ligase activity
XI02_RS32430	COG0752	glycyl-tRNA synthetase alpha subunit
XI02_RS32455	COG0142	geranyltranstransferase activity
XI02_RS32470	COG3708	Transcriptional regulator
XI02_RS32470	COG2207	Transcriptional regulator
XI02_RS32480	COG4948	Mandelate Racemase Muconate Lactonizing
XI02_RS32520	COG2815	serine threonine protein kinase
XI02_RS32520	COG0515	serine threonine protein kinase
XI02_RS32525	COG2116	formate transmembrane transporter activity
XI02_RS32550	COG2207	Transcriptional regulator
XI02_RS32560	COG4774	siderophore transport
XI02_RS32570	COG4948	Mandelate Racemase Muconate Lactonizing
XI02_RS32580	COG0386	Belongs to the glutathione peroxidase family
XI02_RS32585	COG0154	amidase activity
XI02_RS32610	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
XI02_RS32615	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
XI02_RS32620	COG0535	radical SAM domain protein
XI02_RS32625	COG0535	radical SAM domain protein
XI02_RS32645	COG0493	'glutamate synthase
XI02_RS32650	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
XI02_RS32650	COG0674	pyruvate-flavodoxin oxidoreductase activity
XI02_RS32655	COG1013	pyruvate-flavodoxin oxidoreductase activity
XI02_RS32665	COG2719	SpoVR family
XI02_RS32670	COG2718	Belongs to the UPF0229 family
XI02_RS32675	COG2766	serine protein kinase
XI02_RS32690	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XI02_RS32695	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XI02_RS32700	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XI02_RS32705	COG0363	glucosamine-6-phosphate deaminase activity
XI02_RS32710	COG3265	gluconokinase activity
XI02_RS32715	COG0561	phosphatase activity
XI02_RS32720	COG3387	PFAM Glycoside hydrolase 15-related
XI02_RS32725	COG1640	4-alpha-glucanotransferase
XI02_RS32730	COG0366	Alpha amylase catalytic
XI02_RS32735	COG0366	Alpha amylase catalytic
XI02_RS32740	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XI02_RS32750	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XI02_RS32775	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
XI02_RS32790	COG2205	protein histidine kinase activity
XI02_RS32795	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
XI02_RS32800	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XI02_RS32805	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XI02_RS32830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XI02_RS32840	COG0330	HflC and HflK could
XI02_RS32860	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
XI02_RS32870	COG2223	nitrite transmembrane transporter activity
XI02_RS32880	COG1763	Mo-molybdopterin cofactor biosynthetic process
XI02_RS32955	COG1672	PFAM Archaeal ATPase
XI02_RS32955	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XI02_RS32975	COG3684	Belongs to the aldolase LacD family
XI02_RS32980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XI02_RS32985	COG3842	ATPase activity
XI02_RS32990	COG1063	alcohol dehydrogenase
XI02_RS33005	COG1653	transport
XI02_RS33015	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS33020	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XI02_RS33065	COG0235	Class ii aldolase
XI02_RS33070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XI02_RS33080	COG3842	ATPase activity
XI02_RS33095	COG1175	transmembrane transport
XI02_RS33100	COG1653	transport
XI02_RS33110	COG1070	Carbohydrate kinase
XI02_RS33115	COG0647	UMP catabolic process
XI02_RS33125	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XI02_RS33135	COG2271	Major facilitator Superfamily
XI02_RS33145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XI02_RS33150	COG0583	DNA-binding transcription factor activity
XI02_RS33160	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
XI02_RS33185	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XI02_RS33205	COG1566	PFAM secretion protein HlyD family protein
XI02_RS33220	COG3119	arylsulfatase activity
XI02_RS33230	COG2304	oxidoreductase activity
XI02_RS33250	COG0714	Associated with various cellular activities
XI02_RS33255	COG3119	arylsulfatase activity
XI02_RS33260	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XI02_RS33285	COG1024	Enoyl-CoA hydratase
XI02_RS33290	COG0405	Gamma-glutamyltransferase
XI02_RS33300	COG4106	trans-aconitate 2-methyltransferase activity
XI02_RS33310	COG1672	PFAM Archaeal ATPase
XI02_RS33310	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XI02_RS33315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XI02_RS33320	COG1126	abc transporter atp-binding protein
XI02_RS33325	COG0765	amino acid transport
XI02_RS33330	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
XI02_RS33345	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XI02_RS33350	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XI02_RS33355	COG2080	2 iron, 2 sulfur cluster binding
XI02_RS33380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XI02_RS33385	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XI02_RS33415	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XI02_RS33430	COG1595	DNA-templated transcription, initiation
XI02_RS33450	COG3766	membrane
XI02_RS33465	COG0754	glutathionylspermidine amidase activity
XI02_RS33475	COG2201	protein-glutamate methylesterase activity
XI02_RS33480	COG0643	Histidine kinase
XI02_RS33480	COG0784	Response regulator, receiver
XI02_RS33480	COG2198	Histidine kinase
XI02_RS33485	COG0835	chemotaxis
XI02_RS33490	COG0784	Response regulator, receiver
XI02_RS33490	COG2198	Histidine kinase
XI02_RS33490	COG0643	Histidine kinase
XI02_RS33500	COG1218	3'(2'),5'-bisphosphate nucleotidase
XI02_RS33550	COG0028	Belongs to the TPP enzyme family
XI02_RS33555	COG1376	ErfK ybiS ycfS ynhG family protein
XI02_RS33565	COG3547	Transposase (IS116 IS110 IS902 family)
XI02_RS33575	COG0583	DNA-binding transcription factor activity
XI02_RS33580	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
XI02_RS33595	COG0501	Belongs to the peptidase M48B family
XI02_RS33645	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XI02_RS33660	COG0583	DNA-binding transcription factor activity
XI02_RS33665	COG1960	acyl-CoA dehydrogenase activity
XI02_RS33670	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XI02_RS33675	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
XI02_RS33680	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XI02_RS33700	COG0596	Alpha beta hydrolase
XI02_RS33705	COG1335	isochorismatase
XI02_RS33740	COG1309	transcriptional regulator
XI02_RS33750	COG1272	protein, Hemolysin III
XI02_RS33755	COG3106	COG3106 Predicted ATPase
XI02_RS33760	COG3768	UPF0283 membrane protein
XI02_RS33790	COG1278	Cold shock
XI02_RS33840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XI02_RS33855	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
XI02_RS33860	COG1704	LemA family
XI02_RS33865	COG1024	Enoyl-CoA hydratase
XI02_RS33870	COG1960	acyl-CoA dehydrogenase activity
XI02_RS33875	COG1960	acyl-CoA dehydrogenase activity
XI02_RS33890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XI02_RS33895	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XI02_RS33915	COG2723	6-phospho-beta-galactosidase activity
XI02_RS33920	COG1454	alcohol dehydrogenase
XI02_RS33950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XI02_RS33955	COG2197	response regulator
XI02_RS33970	COG4948	Mandelate Racemase Muconate Lactonizing
XI02_RS33975	COG1473	amidohydrolase
XI02_RS33985	COG0601	transmembrane transport
XI02_RS33990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XI02_RS33995	COG0444	Belongs to the ABC transporter superfamily
XI02_RS34000	COG4608	Belongs to the ABC transporter superfamily
XI02_RS34040	COG1069	ribulokinase activity
XI02_RS34045	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS34075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XI02_RS34080	COG4651	solute:proton antiporter activity
XI02_RS34080	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XI02_RS34100	COG0484	heat shock protein binding
XI02_RS34115	COG0542	response to heat
XI02_RS34125	COG2837	iron assimilation
XI02_RS34150	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XI02_RS34185	COG0438	transferase activity, transferring glycosyl groups
XI02_RS34210	COG1454	alcohol dehydrogenase
XI02_RS34215	COG1024	Enoyl-CoA hydratase
XI02_RS34225	COG0183	Belongs to the thiolase family
XI02_RS34235	COG1960	acyl-CoA dehydrogenase activity
XI02_RS34245	COG0318	PFAM AMP-dependent synthetase and ligase
XI02_RS34265	COG0596	Alpha beta hydrolase
XI02_RS34300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XI02_RS34305	COG0641	radical SAM
XI02_RS34320	COG1615	UPF0182 protein
XI02_RS34380	COG1473	amidohydrolase
XI02_RS34390	COG1335	isochorismatase
XI02_RS34455	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XI02_RS34525	COG4191	Histidine kinase
XI02_RS34560	COG3550	peptidyl-serine autophosphorylation
XI02_RS34565	COG1960	acyl-CoA dehydrogenase activity
XI02_RS34580	COG1172	Belongs to the binding-protein-dependent transport system permease family
XI02_RS34615	COG0009	L-threonylcarbamoyladenylate synthase
XI02_RS34620	COG0277	FAD linked oxidase domain protein
XI02_RS34625	COG0456	acetyltransferase
XI02_RS34630	COG0494	nUDIX hydrolase
XI02_RS34650	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS34655	COG2204	response regulator
XI02_RS34685	COG0640	Transcriptional regulator
XI02_RS34760	COG1376	ErfK ybiS ycfS ynhG family protein
XI02_RS34770	COG2897	thiosulfate sulfurtransferase activity
XI02_RS34785	COG3706	GGDEF domain
XI02_RS34785	COG4251	negative regulation of phosphorylation
XI02_RS34785	COG2203	Gaf domain
XI02_RS34785	COG5001	Diguanylate cyclase
XI02_RS34790	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XI02_RS34795	COG2072	flavoprotein involved in K transport
XI02_RS34800	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XI02_RS34815	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
XI02_RS34830	COG1573	uracil-dna glycosylase
XI02_RS34840	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
XI02_RS34870	COG0521	Mo-molybdopterin cofactor biosynthetic process
XI02_RS34875	COG2321	neutral zinc metallopeptidase
XI02_RS34885	COG2189	Belongs to the N(4) N(6)-methyltransferase family
XI02_RS34895	COG0625	glutathione transferase activity
XI02_RS34910	COG0625	glutathione transferase activity
XI02_RS34925	COG1194	a g-specific adenine glycosylase
XI02_RS34940	COG1196	nuclear chromosome segregation
XI02_RS34950	COG1704	LemA family
XI02_RS34970	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XI02_RS34990	COG2857	Cytochrome c1
XI02_RS34990	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XI02_RS34995	COG0723	plastoquinol--plastocyanin reductase activity
XI02_RS35000	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XI02_RS35005	COG0602	queuosine metabolic process
XI02_RS35015	COG0408	coproporphyrinogen oxidase activity
XI02_RS35020	COG0546	phosphoglycolate phosphatase activity
XI02_RS35035	COG0617	tRNA 3'-terminal CCA addition
XI02_RS35055	COG0714	Associated with various cellular activities
XI02_RS35080	COG4771	TonB-dependent receptor
XI02_RS35095	COG0494	nUDIX hydrolase
XI02_RS35140	COG0667	Aldo Keto reductase
XI02_RS35145	COG0501	Belongs to the peptidase M48B family
XI02_RS35170	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS35175	COG1902	pentaerythritol trinitrate reductase activity
XI02_RS35190	COG0395	ABC-type sugar transport system, permease component
XI02_RS35200	COG3842	ATPase activity
XI02_RS35205	COG3842	ATPase activity
XI02_RS35220	COG1349	DNA-binding transcription factor activity
XI02_RS35230	COG1607	acyl-coa hydrolase
XI02_RS35280	COG3214	Protein conserved in bacteria
XI02_RS35325	COG3237	CsbD-like
XI02_RS35330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XI02_RS35340	COG0405	Gamma-glutamyltransferase
XI02_RS35345	COG1054	Belongs to the UPF0176 family
XI02_RS35350	COG2900	Belongs to the SlyX family
XI02_RS35380	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XI02_RS35390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XI02_RS35400	COG3300	MHYT domain
XI02_RS35400	COG5001	Diguanylate cyclase
XI02_RS35425	COG5001	Diguanylate cyclase
XI02_RS35425	COG5002	protein histidine kinase activity
XI02_RS35450	COG1024	Enoyl-CoA hydratase
XI02_RS35475	COG1309	transcriptional regulator
XI02_RS35480	COG3386	PFAM SMP-30 Gluconolaconase
XI02_RS35485	COG2017	converts alpha-aldose to the beta-anomer
XI02_RS35510	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XI02_RS35515	COG2271	Major facilitator Superfamily
XI02_RS35520	COG0583	DNA-binding transcription factor activity
XI02_RS35525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XI02_RS35530	COG4948	Mandelate Racemase Muconate Lactonizing
XI02_RS35535	COG1012	belongs to the aldehyde dehydrogenase family
XI02_RS35540	COG2721	sulfolactate sulfo-lyase activity
XI02_RS35565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XI02_RS35580	COG0473	3-isopropylmalate dehydrogenase activity
XI02_RS35585	COG0066	3-isopropylmalate dehydratase activity
XI02_RS35590	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XI02_RS35600	COG0686	Belongs to the AlaDH PNT family
XI02_RS35605	COG1522	sequence-specific DNA binding
XI02_RS35615	COG0519	Catalyzes the synthesis of GMP from XMP
XI02_RS35615	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XI02_RS35625	COG0583	DNA-binding transcription factor activity
XI02_RS35635	COG0583	DNA-binding transcription factor activity
XI02_RS35645	COG2814	Major facilitator Superfamily
XI02_RS35655	COG2159	amidohydrolase
XI02_RS35660	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XI02_RS35670	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS35680	COG0583	DNA-binding transcription factor activity
XI02_RS35695	COG0729	surface antigen
XI02_RS35740	COG5441	Belongs to the UPF0261 family
XI02_RS35745	COG5564	TIM-barrel signal transduction protein
XI02_RS35750	COG2268	Band 7 protein
XI02_RS35750	COG2268	Band 7 protein
XI02_RS35775	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XI02_RS35795	COG3618	amidohydrolase
XI02_RS35805	COG3386	PFAM SMP-30 Gluconolaconase
XI02_RS35810	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XI02_RS35815	COG2205	protein histidine kinase activity
XI02_RS35820	COG0745	RESPONSE REGULATOR receiver
XI02_RS35830	COG0753	catalase activity
XI02_RS35880	COG1024	Enoyl-CoA hydratase
XI02_RS35885	COG2030	dehydratase
XI02_RS35885	COG1012	belongs to the aldehyde dehydrogenase family
XI02_RS35910	COG1464	Belongs to the NlpA lipoprotein family
XI02_RS35915	COG1464	Belongs to the NlpA lipoprotein family
XI02_RS35920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XI02_RS35925	COG2011	ABC-type metal ion transport system permease component
XI02_RS35930	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XI02_RS35940	COG0445	tRNA wobble uridine modification
XI02_RS35950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XI02_RS35955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XI02_RS35960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XI02_RS35965	COG1116	anion transmembrane transporter activity
XI02_RS35975	COG1960	acyl-CoA dehydrogenase activity
XI02_RS36010	COG2072	flavoprotein involved in K transport
XI02_RS36015	COG2226	methyltransferase
XI02_RS36020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XI02_RS36025	COG1464	Belongs to the NlpA lipoprotein family
XI02_RS36030	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS36035	COG1940	carbohydrate kinase activity
XI02_RS36045	COG1129	ABC transporter
XI02_RS36050	COG1172	Belongs to the binding-protein-dependent transport system permease family
XI02_RS36065	COG0549	Belongs to the carbamate kinase family
XI02_RS36070	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XI02_RS36075	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XI02_RS36080	COG1304	FMN binding
XI02_RS36095	COG0559	Belongs to the binding-protein-dependent transport system permease family
XI02_RS36135	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
XI02_RS36145	COG3206	protein involved in exopolysaccharide biosynthesis
XI02_RS36145	COG0489	protein tyrosine kinase activity
XI02_RS36150	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
XI02_RS36170	COG2244	polysaccharide biosynthetic process
XI02_RS36185	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
XI02_RS36200	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
XI02_RS36205	COG4310	Domain of unknown function (DUF2172)
XI02_RS36225	COG3307	-O-antigen
XI02_RS36235	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XI02_RS36235	COG2755	lipolytic protein G-D-S-L family
XI02_RS36290	COG1125	glycine betaine transport
XI02_RS36290	COG0517	IMP dehydrogenase activity
XI02_RS36300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XI02_RS36310	COG1960	acyl-CoA dehydrogenase activity
XI02_RS36315	COG1024	Enoyl-CoA hydratase
XI02_RS36325	COG1129	ABC transporter
XI02_RS36350	COG4670	ketone body catabolic process
XI02_RS36355	COG1024	Enoyl-CoA hydratase
XI02_RS36370	COG1902	pentaerythritol trinitrate reductase activity
XI02_RS36390	COG2079	MmgE PrpD family protein
XI02_RS36400	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XI02_RS36405	COG1024	Enoyl-CoA hydratase
XI02_RS36415	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS36440	COG0559	Belongs to the binding-protein-dependent transport system permease family
XI02_RS36465	COG0318	PFAM AMP-dependent synthetase and ligase
XI02_RS36570	COG0028	Belongs to the TPP enzyme family
XI02_RS36585	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS36610	COG1793	dna ligase
XI02_RS36620	COG0723	plastoquinol--plastocyanin reductase activity
XI02_RS36620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XI02_RS36625	COG3685	Protein conserved in bacteria
XI02_RS36630	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XI02_RS36670	COG4297	protein containing double-stranded beta helix domain
XI02_RS36675	COG3546	catalase activity
XI02_RS36715	COG1484	DNA-dependent DNA replication
XI02_RS36720	COG4584	PFAM Integrase catalytic
XI02_RS36760	COG2963	transposase activity
XI02_RS36765	COG3436	PFAM IS66 Orf2 family protein
XI02_RS36795	COG5489	Protein of unknown function (DUF736)
XI02_RS36850	COG0459	protein refolding
XI02_RS36855	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XI02_RS36915	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XI02_RS36975	COG3239	Fatty acid desaturase
XI02_RS37035	COG0596	Alpha beta hydrolase
XI02_RS37050	COG0596	Alpha beta hydrolase
XI02_RS37090	COG1482	cell wall glycoprotein biosynthetic process
XI02_RS37160	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XI02_RS37245	COG0736	holo-[acyl-carrier-protein] synthase activity
XI02_RS37265	COG0482	sulfurtransferase activity
XI02_RS37275	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XI02_RS37345	COG1766	The M ring may be actively involved in energy transduction
XI02_RS37350	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
XI02_RS37360	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
XI02_RS37365	COG2204	response regulator
XI02_RS37380	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XI02_RS37385	COG1116	anion transmembrane transporter activity
XI02_RS37390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XI02_RS37395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XI02_RS37400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XI02_RS37405	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XI02_RS37410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XI02_RS37415	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XI02_RS37420	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XI02_RS37425	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XI02_RS37445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XI02_RS37460	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XI02_RS37465	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XI02_RS37555	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XI02_RS37565	COG1175	transmembrane transport
XI02_RS37570	COG0395	ABC-type sugar transport system, permease component
XI02_RS37580	COG0848	biopolymer transport protein
XI02_RS37600	COG4771	TonB-dependent receptor
XI02_RS37610	COG4558	Periplasmic binding protein
XI02_RS37615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XI02_RS37620	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
XI02_RS37640	COG0183	Belongs to the thiolase family
XI02_RS37645	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XI02_RS37675	COG2223	nitrite transmembrane transporter activity
XI02_RS37680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XI02_RS37705	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XI02_RS37715	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XI02_RS37740	COG0436	Aminotransferase
XI02_RS37775	COG0667	Aldo Keto reductase
XI02_RS37790	COG0546	phosphoglycolate phosphatase activity
XI02_RS37800	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
XI02_RS37810	COG3119	arylsulfatase activity
XI02_RS37820	COG1024	Enoyl-CoA hydratase
XI02_RS37825	COG0625	glutathione transferase activity
XI02_RS37840	COG1999	signal sequence binding
XI02_RS37855	COG2072	flavoprotein involved in K transport
XI02_RS37860	COG2755	lipolytic protein G-D-S-L family
XI02_RS37860	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XI02_RS37875	COG0556	nucleotide-excision repair
XI02_RS37905	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XI02_RS37950	COG2030	dehydratase
XI02_RS37965	COG1192	Involved in chromosome partitioning
XI02_RS37995	COG2181	nitrate reductase activity
XI02_RS38000	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
XI02_RS38005	COG1140	nitrate reductase beta subunit
XI02_RS38010	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
XI02_RS38015	COG2223	nitrite transmembrane transporter activity
XI02_RS38045	COG2217	Heavy metal translocating P-type atpase
XI02_RS38060	COG2010	Cytochrome c
XI02_RS38075	COG3278	Belongs to the heme-copper respiratory oxidase family
XI02_RS38100	COG4191	Histidine kinase
XI02_RS38105	COG4566	intracellular signal transduction
XI02_RS38135	COG3218	ABC-type transport auxiliary lipoprotein component
XI02_RS38135	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XI02_RS38140	COG1127	ABC transporter
XI02_RS38145	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XI02_RS38155	COG0045	succinate-CoA ligase (ADP-forming) activity
XI02_RS38155	COG1042	CoA-binding domain protein
XI02_RS38155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XI02_RS38160	COG4109	DRTGG domain
XI02_RS38165	COG0071	Belongs to the small heat shock protein (HSP20) family
XI02_RS38195	COG3243	poly(R)-hydroxyalkanoic acid synthase
XI02_RS38205	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
XI02_RS38225	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
XI02_RS38230	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XI02_RS38235	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XI02_RS38245	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
XI02_RS38255	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
XI02_RS38280	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XI02_RS38295	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XI02_RS38300	COG1611	Belongs to the LOG family
XI02_RS38335	COG0563	adenylate kinase activity
XI02_RS38340	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XI02_RS38345	COG3162	membrane
XI02_RS38350	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XI02_RS38360	COG2176	DNA-directed DNA polymerase activity
XI02_RS38380	COG2205	protein histidine kinase activity
XI02_RS38400	COG1802	Transcriptional regulator
XI02_RS38405	COG1012	belongs to the aldehyde dehydrogenase family
XI02_RS38410	COG2814	Major facilitator Superfamily
XI02_RS38430	COG3547	Transposase (IS116 IS110 IS902 family)
XI02_RS38460	COG1175	transmembrane transport
XI02_RS38470	COG1177	transmembrane transport
XI02_RS38475	COG1176	ABC-type spermidine putrescine transport system, permease component I
XI02_RS38480	COG3842	ATPase activity
XI02_RS38510	COG0071	Belongs to the small heat shock protein (HSP20) family
XI02_RS38525	COG0488	(ABC) transporter
XI02_RS38530	COG5001	Diguanylate cyclase
XI02_RS38530	COG3300	MHYT domain
XI02_RS38535	COG0579	oxidoreductase
XI02_RS38560	COG3447	MASE1 domain protein
XI02_RS38560	COG5001	Diguanylate cyclase
XI02_RS38560	COG5002	protein histidine kinase activity
XI02_RS38570	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
XI02_RS38575	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XI02_RS38580	COG0828	Belongs to the bacterial ribosomal protein bS21 family
XI02_RS38600	COG0387	Pfam Sodium calcium exchanger
XI02_RS38635	COG1164	Oligoendopeptidase f
XI02_RS38645	COG2989	Protein conserved in bacteria
XI02_RS38660	COG3750	Belongs to the UPF0335 family
XI02_RS38675	COG0469	pyruvate kinase activity
XI02_RS38680	COG1764	response to oxidative stress
XI02_RS38685	COG1309	transcriptional regulator
XI02_RS38705	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XI02_RS38710	COG0037	tRNA processing
XI02_RS38715	COG0037	tRNA processing
XI02_RS38725	COG2885	chlorophyll binding
XI02_RS38735	COG5001	Diguanylate cyclase
XI02_RS38740	COG0823	Involved in the tonB-independent uptake of proteins
XI02_RS38750	COG0848	biopolymer transport protein
XI02_RS38760	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XI02_RS38765	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XI02_RS38790	COG0523	cobalamin synthesis protein
XI02_RS38795	COG0326	Molecular chaperone. Has ATPase activity
XI02_RS38800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XI02_RS38810	COG1595	DNA-templated transcription, initiation
XI02_RS38815	COG0252	asparaginase activity
XI02_RS38835	COG2814	Major facilitator Superfamily
XI02_RS38865	COG3038	cytochrome b561
XI02_RS38885	COG2217	Heavy metal translocating P-type atpase
XI02_RS38900	COG2010	Cytochrome c
XI02_RS38915	COG3278	Belongs to the heme-copper respiratory oxidase family
XI02_RS38955	COG4191	Histidine kinase
XI02_RS38960	COG4566	intracellular signal transduction
XI02_RS38975	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
XI02_RS38985	COG3218	ABC-type transport auxiliary lipoprotein component
XI02_RS38985	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XI02_RS38990	COG1127	ABC transporter
XI02_RS38995	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XI02_RS39005	COG1042	CoA-binding domain protein
XI02_RS39005	COG0045	succinate-CoA ligase (ADP-forming) activity
XI02_RS39005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XI02_RS39010	COG4109	DRTGG domain
XI02_RS39015	COG0071	Belongs to the small heat shock protein (HSP20) family
XI02_RS39075	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
XI02_RS39085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XI02_RS39090	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XI02_RS39100	COG0516	GMP reductase activity
XI02_RS39100	COG0517	IMP dehydrogenase activity
XI02_RS39110	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
XI02_RS39135	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XI02_RS39150	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XI02_RS39155	COG1611	Belongs to the LOG family
XI02_RS39180	COG2433	Pfam Transposase IS66
XI02_RS39185	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XI02_RS39195	COG3436	PFAM IS66 Orf2 family protein
XI02_RS39200	COG2963	transposase activity
XI02_RS39205	COG1280	lysine exporter protein (LysE YggA)
XI02_RS39220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XI02_RS39325	COG2610	gluconate transmembrane transporter activity
XI02_RS39340	COG4716	Myosin-crossreactive antigen
XI02_RS39385	COG0525	valine-tRNA ligase activity
XI02_RS39390	COG2801	Transposase and inactivated derivatives
XI02_RS39515	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XI02_RS39520	COG3415	Transposase
XI02_RS39540	COG4974	Belongs to the 'phage' integrase family
XI02_RS39550	COG0582	viral genome integration into host DNA
XI02_RS39590	COG0720	synthase
XI02_RS39620	COG1858	cytochrome C peroxidase
XI02_RS39645	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XI02_RS39685	COG4974	Belongs to the 'phage' integrase family
XI02_RS39705	COG1215	transferase activity, transferring glycosyl groups
XI02_RS39710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XI02_RS39715	COG3318	Belongs to the UPF0149 family
XI02_RS39730	COG2433	Pfam Transposase IS66
XI02_RS39820	COG2192	nodulation
XI02_RS39865	COG3838	Conjugal transfer protein Trbc
XI02_RS39870	COG4962	Type ii secretion system protein e
XI02_RS39935	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XI02_RS39945	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XI02_RS39950	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XI02_RS39960	COG0019	diaminopimelate decarboxylase activity
XI02_RS40035	COG5265	(ABC) transporter
XI02_RS40080	COG3318	Belongs to the UPF0149 family
XI02_RS40090	COG3318	Belongs to the UPF0149 family
XI02_RS40095	COG2433	Pfam Transposase IS66
XI02_RS40100	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XI02_RS40105	COG3436	PFAM IS66 Orf2 family protein
XI02_RS40110	COG2963	transposase activity
XI02_RS40115	COG5001	Diguanylate cyclase
XI02_RS40115	COG3300	MHYT domain
XI02_RS40120	COG3706	GGDEF domain
XI02_RS40145	COG2948	multi-organism process
XI02_RS40155	COG3701	Conjugal transfer protein
XI02_RS40175	COG3451	type IV secretory pathway VirB4
XI02_RS40185	COG3838	Conjugal transfer protein Trbc
XI02_RS40190	COG4962	Type ii secretion system protein e
XI02_RS40245	COG1192	Involved in chromosome partitioning
XI02_RS40290	COG5489	Protein of unknown function (DUF736)
XI02_RS40380	COG1012	belongs to the aldehyde dehydrogenase family
XI02_RS40390	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS40400	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS40405	COG0604	alcohol dehydrogenase
XI02_RS40430	COG0179	Fumarylacetoacetate (FAA) hydrolase
XI02_RS40440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XI02_RS40450	COG2267	carboxylic ester hydrolase activity
XI02_RS40460	COG1595	DNA-templated transcription, initiation
XI02_RS40470	COG1802	Transcriptional regulator
XI02_RS40475	COG5285	phytanoyl-CoA dioxygenase
XI02_RS40490	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
XI02_RS40530	COG0739	heme binding
XI02_RS40545	COG0542	response to heat
XI02_RS40580	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XI02_RS40580	COG2813	Specifically methylates the guanine in position
XI02_RS40585	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XI02_RS40595	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XI02_RS40600	COG0287	Prephenate dehydrogenase
XI02_RS40605	COG0346	lactoylglutathione lyase activity
XI02_RS40650	COG1335	isochorismatase
XI02_RS40665	COG1012	belongs to the aldehyde dehydrogenase family
XI02_RS40690	COG2884	Cell division ATP-binding protein ftsE
XI02_RS40700	COG2204	response regulator
XI02_RS40725	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XI02_RS40735	COG0019	diaminopimelate decarboxylase activity
XI02_RS40745	COG0165	Argininosuccinate lyase
XI02_RS40750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XI02_RS40760	COG0583	DNA-binding transcription factor activity
XI02_RS40765	COG0436	Aminotransferase
XI02_RS40770	COG1250	3-hydroxyacyl-CoA dehydrogenase
XI02_RS40775	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
XI02_RS40780	COG2086	electron transfer activity
XI02_RS40800	COG0784	Response regulator, receiver
XI02_RS40800	COG2198	Histidine kinase
XI02_RS40800	COG5002	protein histidine kinase activity
XI02_RS40805	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XI02_RS40820	COG0583	DNA-binding transcription factor activity
XI02_RS40880	COG1289	transmembrane transporter activity
XI02_RS40890	COG1566	PFAM secretion protein HlyD family protein
XI02_RS40925	COG3511	phospholipase C
XI02_RS40985	COG1459	type II secretion system
XI02_RS40990	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XI02_RS40995	COG1450	Type ii and iii secretion system protein
XI02_RS41010	COG4774	siderophore transport
XI02_RS41020	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
XI02_RS41030	COG1132	(ABC) transporter
XI02_RS41035	COG0254	rRNA binding
XI02_RS41050	COG4191	Histidine kinase
XI02_RS41050	COG0784	Response regulator, receiver
XI02_RS41055	COG1280	lysine exporter protein (LysE YggA)
XI02_RS41065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XI02_RS41085	COG3321	synthase
XI02_RS41085	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS41085	COG0604	alcohol dehydrogenase
XI02_RS41100	COG2203	Gaf domain
XI02_RS41100	COG3706	GGDEF domain
XI02_RS41100	COG5001	Diguanylate cyclase
XI02_RS41100	COG4251	negative regulation of phosphorylation
XI02_RS41105	COG0513	Belongs to the DEAD box helicase family
XI02_RS41125	COG0596	Alpha beta hydrolase
XI02_RS41165	COG3064	Membrane
XI02_RS41180	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XI02_RS41205	COG2814	Major facilitator Superfamily
XI02_RS41210	COG2309	aminopeptidase activity
XI02_RS41215	COG0596	Alpha beta hydrolase
XI02_RS41220	COG1335	isochorismatase
XI02_RS41225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XI02_RS41245	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XI02_RS41260	COG2207	Transcriptional regulator
XI02_RS41270	COG0318	PFAM AMP-dependent synthetase and ligase
XI02_RS41275	COG1024	Enoyl-CoA hydratase
XI02_RS41290	COG1024	Enoyl-CoA hydratase
XI02_RS41300	COG1129	ABC transporter
XI02_RS41315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XI02_RS41320	COG0346	lactoylglutathione lyase activity
XI02_RS41330	COG4770	biotin carboxylase activity
XI02_RS41335	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XI02_RS41340	COG3800	Transcriptional regulator
XI02_RS41340	COG1396	sequence-specific DNA binding
XI02_RS41345	COG1522	sequence-specific DNA binding
XI02_RS41400	COG0828	Belongs to the bacterial ribosomal protein bS21 family
XI02_RS41405	COG1278	Cold shock
XI02_RS41430	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XI02_RS41445	COG1309	transcriptional regulator
XI02_RS41450	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XI02_RS41450	COG2010	Cytochrome c
XI02_RS41455	COG2080	2 iron, 2 sulfur cluster binding
XI02_RS41460	COG2010	Cytochrome c
XI02_RS41460	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XI02_RS41465	COG2814	Major facilitator Superfamily
XI02_RS41470	COG1902	pentaerythritol trinitrate reductase activity
XI02_RS41480	COG0583	DNA-binding transcription factor activity
XI02_RS41485	COG0346	lactoylglutathione lyase activity
XI02_RS41490	COG0400	carboxylic ester hydrolase activity
XI02_RS41520	COG1228	amidohydrolase
XI02_RS41550	COG0583	DNA-binding transcription factor activity
XI02_RS41555	COG0346	lactoylglutathione lyase activity
XI02_RS41565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XI02_RS41600	COG3321	synthase
XI02_RS41600	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS41600	COG0604	alcohol dehydrogenase
XI02_RS41685	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XI02_RS41800	COG0582	viral genome integration into host DNA
XI02_RS41810	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
XI02_RS41815	COG0424	maF-like protein
XI02_RS41825	COG5328	Belongs to the UPF0262 family
XI02_RS41830	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XI02_RS41855	COG3634	alkyl hydroperoxide reductase activity
XI02_RS41895	COG0156	8-amino-7-oxononanoate synthase activity
XI02_RS41900	COG2198	Histidine kinase
XI02_RS41900	COG0784	Response regulator, receiver
XI02_RS41900	COG2205	protein histidine kinase activity
XI02_RS41915	COG0477	Major facilitator Superfamily
XI02_RS41920	COG0432	Pfam Uncharacterised protein family UPF0047
XI02_RS41940	COG0356	it plays a direct role in the translocation of protons across the membrane
XI02_RS41950	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XI02_RS41955	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XI02_RS41965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XI02_RS41970	COG0612	Peptidase, M16
XI02_RS42020	COG2059	Chromate
XI02_RS42065	COG0583	DNA-binding transcription factor activity
XI02_RS42070	COG0598	Magnesium transport protein CorA
XI02_RS42090	COG2814	Major facilitator Superfamily
XI02_RS42095	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
XI02_RS42095	COG0456	acetyltransferase
XI02_RS42100	COG3346	SURF1 family
XI02_RS42115	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XI02_RS42125	COG0109	protoheme IX farnesyltransferase activity
XI02_RS42130	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XI02_RS42135	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XI02_RS42165	COG1733	regulation of RNA biosynthetic process
XI02_RS42170	COG0312	modulator of DNA gyrase
XI02_RS42175	COG0681	Belongs to the peptidase S26 family
XI02_RS42205	COG0625	glutathione transferase activity
XI02_RS42215	COG1250	3-hydroxyacyl-CoA dehydrogenase
XI02_RS42215	COG1024	Enoyl-CoA hydratase
XI02_RS42220	COG0183	Belongs to the thiolase family
XI02_RS42225	COG1960	acyl-CoA dehydrogenase activity
XI02_RS42250	COG0730	response to heat
XI02_RS42260	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
XI02_RS42265	COG1522	sequence-specific DNA binding
XI02_RS42280	COG0697	spore germination
XI02_RS42285	COG0583	DNA-binding transcription factor activity
XI02_RS42295	COG1201	RNA secondary structure unwinding
XI02_RS42325	COG1234	tRNA 3'-trailer cleavage
XI02_RS42330	COG0534	Mate efflux family protein
XI02_RS42335	COG0167	dihydroorotate dehydrogenase activity
XI02_RS42365	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
XI02_RS42375	COG1999	signal sequence binding
XI02_RS42400	COG1733	regulation of RNA biosynthetic process
XI02_RS42410	COG0251	oxidation-reduction process
XI02_RS42440	COG3794	PFAM blue (type 1) copper domain protein
XI02_RS42465	COG1902	pentaerythritol trinitrate reductase activity
XI02_RS42470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XI02_RS42490	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
XI02_RS42490	COG2169	Transcriptional regulator
XI02_RS42520	COG0717	Belongs to the dCTP deaminase family
XI02_RS42530	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS42535	COG1960	acyl-CoA dehydrogenase activity
XI02_RS42540	COG1960	acyl-CoA dehydrogenase activity
XI02_RS42545	COG0183	Belongs to the thiolase family
XI02_RS42550	COG0318	PFAM AMP-dependent synthetase and ligase
XI02_RS42625	COG3268	Saccharopine dehydrogenase
XI02_RS42655	COG2852	Protein conserved in bacteria
XI02_RS42675	COG0318	PFAM AMP-dependent synthetase and ligase
XI02_RS42680	COG1024	Enoyl-CoA hydratase
XI02_RS42715	COG0583	DNA-binding transcription factor activity
XI02_RS42805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XI02_RS42810	COG1024	Enoyl-CoA hydratase
XI02_RS42825	COG2378	regulation of single-species biofilm formation
XI02_RS42835	COG0778	Nitroreductase
XI02_RS42840	COG1960	acyl-CoA dehydrogenase activity
XI02_RS42845	COG1960	acyl-CoA dehydrogenase activity
XI02_RS42850	COG1960	acyl-CoA dehydrogenase activity
XI02_RS42855	COG3320	Male sterility
XI02_RS42855	COG1022	Amp-dependent synthetase and ligase
XI02_RS42890	COG2267	carboxylic ester hydrolase activity
XI02_RS42905	COG3038	cytochrome b561
XI02_RS42920	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
XI02_RS42925	COG1960	acyl-CoA dehydrogenase activity
XI02_RS42930	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS42935	COG1024	Enoyl-CoA hydratase
XI02_RS42950	COG0583	DNA-binding transcription factor activity
XI02_RS42960	COG1053	succinate dehydrogenase
XI02_RS42990	COG1058	Belongs to the CinA family
XI02_RS42990	COG1546	Belongs to the CinA family
XI02_RS42995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XI02_RS43000	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
XI02_RS43010	COG0583	DNA-binding transcription factor activity
XI02_RS43020	COG0154	amidase activity
XI02_RS43030	COG4608	Belongs to the ABC transporter superfamily
XI02_RS43035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XI02_RS43040	COG0601	transmembrane transport
XI02_RS43045	COG0747	negative chemotaxis
XI02_RS43050	COG0747	negative chemotaxis
XI02_RS43070	COG0683	leucine binding
XI02_RS43100	COG4555	ABC transporter
XI02_RS43130	COG2309	aminopeptidase activity
XI02_RS43135	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
XI02_RS43145	COG3181	Tripartite tricarboxylate transporter family receptor
XI02_RS43150	COG2084	Dehydrogenase
XI02_RS43155	COG0673	inositol 2-dehydrogenase activity
XI02_RS43160	COG2188	Transcriptional regulator
XI02_RS43185	COG0028	Belongs to the TPP enzyme family
XI02_RS43215	COG1181	Belongs to the D-alanine--D-alanine ligase family
XI02_RS43230	COG4941	Belongs to the sigma-70 factor family
XI02_RS43250	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XI02_RS43255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XI02_RS43265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XI02_RS43280	COG1937	Protein conserved in bacteria
XI02_RS43295	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
XI02_RS43305	COG0069	glutamate synthase activity
XI02_RS43345	COG1301	dicarboxylic acid transport
XI02_RS43350	COG2130	NADP-dependent
XI02_RS43400	COG0625	glutathione transferase activity
XI02_RS43425	COG0445	tRNA wobble uridine modification
XI02_RS43440	COG1024	Enoyl-CoA hydratase
XI02_RS43465	COG2010	Cytochrome c
XI02_RS43475	COG1027	Aspartate ammonia-lyase
XI02_RS43500	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS43505	COG0277	FAD linked oxidase domain protein
XI02_RS43510	COG0546	phosphoglycolate phosphatase activity
XI02_RS43510	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XI02_RS43550	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XI02_RS43570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XI02_RS43575	COG0318	PFAM AMP-dependent synthetase and ligase
XI02_RS43585	COG1902	pentaerythritol trinitrate reductase activity
XI02_RS43600	COG1960	acyl-CoA dehydrogenase activity
XI02_RS43605	COG1024	Enoyl-CoA hydratase
XI02_RS43625	COG1024	Enoyl-CoA hydratase
XI02_RS43660	COG0477	Major facilitator Superfamily
XI02_RS43665	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XI02_RS43670	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XI02_RS43675	COG1845	cytochrome c oxidase, subunit III
XI02_RS43680	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XI02_RS43695	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XI02_RS43710	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XI02_RS43715	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
XI02_RS43730	COG0227	Belongs to the bacterial ribosomal protein bL28 family
XI02_RS43750	COG0657	acetylesterase activity
XI02_RS43755	COG2072	flavoprotein involved in K transport
XI02_RS43800	COG1902	pentaerythritol trinitrate reductase activity
XI02_RS43825	COG0586	Pfam SNARE associated Golgi protein
XI02_RS43830	COG0372	Belongs to the citrate synthase family
XI02_RS43835	COG0372	Belongs to the citrate synthase family
XI02_RS43855	COG4536	flavin adenine dinucleotide binding
XI02_RS43860	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XI02_RS43865	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XI02_RS43875	COG4974	Belongs to the 'phage' integrase family
XI02_RS43880	COG0825	malonyl-CoA metabolic process
XI02_RS43885	COG3034	peptidoglycan biosynthetic process
XI02_RS43900	COG0671	phosphoesterase, PA-phosphatase related
XI02_RS43920	COG1129	ABC transporter
XI02_RS43965	COG2814	Major facilitator Superfamily
XI02_RS43975	COG1309	transcriptional regulator
XI02_RS43980	COG0653	protein targeting
XI02_RS43990	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
XI02_RS44010	COG1040	competence protein
XI02_RS44020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XI02_RS44045	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XI02_RS44055	COG0527	aspartate kinase activity
XI02_RS44060	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
XI02_RS44065	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XI02_RS44105	COG2890	protein-(glutamine-N5) methyltransferase activity
XI02_RS44120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XI02_RS44145	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
XI02_RS44160	COG5001	Diguanylate cyclase
XI02_RS44160	COG3300	MHYT domain
XI02_RS44175	COG0333	Belongs to the bacterial ribosomal protein bL32 family
XI02_RS44180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XI02_RS44185	COG0142	geranyltranstransferase activity
XI02_RS44210	COG3547	Transposase (IS116 IS110 IS902 family)
XI02_RS44215	COG2814	Major facilitator Superfamily
XI02_RS44220	COG1566	PFAM secretion protein HlyD family protein
XI02_RS44230	COG0735	belongs to the Fur family
XI02_RS44245	COG2897	thiosulfate sulfurtransferase activity
XI02_RS44250	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XI02_RS44255	COG2175	clavaminate synthase activity
XI02_RS44265	COG3547	Transposase (IS116 IS110 IS902 family)
XI02_RS44280	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XI02_RS44290	COG0640	Transcriptional regulator
XI02_RS44295	COG3485	protocatechuate 3,4-dioxygenase
XI02_RS44300	COG3485	protocatechuate 3,4-dioxygenase
XI02_RS44305	COG0183	Belongs to the thiolase family
XI02_RS44310	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XI02_RS44330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XI02_RS44340	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XI02_RS44360	COG4191	Histidine kinase
XI02_RS44365	COG4566	intracellular signal transduction
XI02_RS44370	COG4566	intracellular signal transduction
XI02_RS44405	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XI02_RS44450	COG0366	Alpha amylase catalytic
XI02_RS44460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XI02_RS44470	COG0477	Major facilitator Superfamily
XI02_RS44480	COG1028	Short-chain dehydrogenase reductase Sdr
XI02_RS44490	COG5001	Diguanylate cyclase
XI02_RS44490	COG3300	MHYT domain
XI02_RS44545	COG2902	Dehydrogenase
XI02_RS44550	COG3284	Transcriptional regulator
XI02_RS44580	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XI02_RS44595	COG2814	Major facilitator Superfamily
XI02_RS44605	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XI02_RS44610	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XI02_RS44615	COG0156	8-amino-7-oxononanoate synthase activity
XI02_RS44620	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XI02_RS44630	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XI02_RS44665	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XI02_RS44680	COG1032	radical SAM domain protein
XI02_RS44685	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XI02_RS44700	COG5507	3-demethylubiquinone-9 3-methyltransferase
XI02_RS44770	COG0412	Dienelactone hydrolase
XI02_RS44775	COG1596	polysaccharide export
XI02_RS44780	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XI02_RS44790	COG0268	Binds directly to 16S ribosomal RNA