locus-tag	class	description
XH93_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
XH93_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XH93_RS00030	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XH93_RS00035	COG0534	Mate efflux family protein
XH93_RS00070	COG1741	Belongs to the pirin family
XH93_RS00075	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XH93_RS00080	COG1024	Enoyl-CoA hydratase
XH93_RS00085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XH93_RS00120	COG0318	PFAM AMP-dependent synthetase and ligase
XH93_RS00125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XH93_RS00135	COG0180	Tryptophanyl-tRNA synthetase
XH93_RS00150	COG1214	PFAM Peptidase M22, glycoprotease
XH93_RS00165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XH93_RS00170	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XH93_RS00175	COG1702	phosphate starvation-inducible protein PhoH
XH93_RS00180	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XH93_RS00185	COG1253	flavin adenine dinucleotide binding
XH93_RS00190	COG0815	Transfers the fatty acyl group on membrane lipoproteins
XH93_RS00195	COG1396	sequence-specific DNA binding
XH93_RS00205	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XH93_RS00215	COG0779	Required for maturation of 30S ribosomal subunits
XH93_RS00230	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XH93_RS00235	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XH93_RS00240	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XH93_RS00250	COG1185	polyribonucleotide nucleotidyltransferase activity
XH93_RS00255	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XH93_RS00265	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XH93_RS00275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XH93_RS00300	COG0667	Aldo Keto reductase
XH93_RS00305	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XH93_RS00320	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XH93_RS00325	COG2226	methyltransferase
XH93_RS00330	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XH93_RS00335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XH93_RS00340	COG0756	dUTP diphosphatase activity
XH93_RS00345	COG2205	protein histidine kinase activity
XH93_RS00350	COG3178	'Phosphotransferase
XH93_RS00360	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XH93_RS00370	COG1074	ATP-dependent DNA helicase activity
XH93_RS00380	COG1793	dna ligase
XH93_RS00395	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XH93_RS00400	COG0159	tryptophan synthase activity
XH93_RS00405	COG2852	Protein conserved in bacteria
XH93_RS00410	COG0133	tryptophan synthase activity
XH93_RS00415	COG0135	phosphoribosylanthranilate isomerase activity
XH93_RS00425	COG0776	regulation of translation
XH93_RS00430	COG0616	signal peptide processing
XH93_RS00435	COG0539	negative regulation of cytoplasmic translation
XH93_RS00445	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XH93_RS00450	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XH93_RS00465	COG1846	Transcriptional regulator
XH93_RS00470	COG1764	response to oxidative stress
XH93_RS00480	COG1653	transport
XH93_RS00490	COG0395	ABC-type sugar transport system, permease component
XH93_RS00495	COG3842	ATPase activity
XH93_RS00500	COG0071	Belongs to the small heat shock protein (HSP20) family
XH93_RS00525	COG0318	PFAM AMP-dependent synthetase and ligase
XH93_RS00550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XH93_RS00555	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
XH93_RS00560	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
XH93_RS00565	COG1137	ATPase activity
XH93_RS00570	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XH93_RS00575	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XH93_RS00585	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XH93_RS00590	COG2814	Major facilitator Superfamily
XH93_RS00595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XH93_RS00610	COG1968	undecaprenyl-diphosphatase activity
XH93_RS00620	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XH93_RS00640	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XH93_RS00645	COG0291	Belongs to the bacterial ribosomal protein bL35 family
XH93_RS00650	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
XH93_RS00660	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XH93_RS00665	COG2852	Protein conserved in bacteria
XH93_RS00670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XH93_RS00670	COG0072	phenylalanine-tRNA ligase activity
XH93_RS00680	COG1234	tRNA 3'-trailer cleavage
XH93_RS00695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XH93_RS00710	COG2814	Major facilitator Superfamily
XH93_RS00730	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XH93_RS00735	COG0588	phosphoglycerate mutase activity
XH93_RS00740	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
XH93_RS00750	COG0284	orotidine-5'-phosphate decarboxylase activity
XH93_RS00755	COG0431	NADPH-dependent FMN reductase
XH93_RS00760	COG3963	phosphatidate phosphatase activity
XH93_RS00765	COG0484	heat shock protein binding
XH93_RS00770	COG0443	Heat shock 70 kDa protein
XH93_RS00780	COG1335	isochorismatase
XH93_RS00795	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XH93_RS00800	COG1420	regulation of RNA biosynthetic process
XH93_RS00805	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XH93_RS00810	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
XH93_RS00815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XH93_RS00835	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
XH93_RS00840	COG0792	nuclease activity
XH93_RS00845	COG0189	ligase activity
XH93_RS00875	COG1072	(Pantothenic acid kinase))
XH93_RS00880	COG0140	phosphoribosyl-ATP diphosphatase activity
XH93_RS00885	COG0107	imidazoleglycerol-phosphate synthase activity
XH93_RS00890	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XH93_RS00895	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XH93_RS00905	COG0131	Imidazoleglycerol-phosphate dehydratase
XH93_RS00910	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
XH93_RS00925	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
XH93_RS00940	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
XH93_RS00950	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
XH93_RS00955	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XH93_RS00960	COG0237	dephospho-CoA kinase activity
XH93_RS00965	COG0424	maF-like protein
XH93_RS00970	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
XH93_RS00975	COG1981	membrane
XH93_RS00980	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XH93_RS00985	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
XH93_RS00990	COG0445	tRNA wobble uridine modification
XH93_RS00995	COG0357	Ribosomal RNA small subunit methyltransferase G
XH93_RS01020	COG0495	leucyl-tRNA aminoacylation
XH93_RS01025	COG3706	GGDEF domain
XH93_RS01045	COG0745	RESPONSE REGULATOR receiver
XH93_RS01060	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
XH93_RS01065	COG1674	ftsk spoiiie
XH93_RS01080	COG0004	ammonium transporteR
XH93_RS01085	COG0347	Belongs to the P(II) protein family
XH93_RS01090	COG0004	ammonium transporteR
XH93_RS01095	COG0347	Belongs to the P(II) protein family
XH93_RS01105	COG1946	Acyl-CoA thioesterase
XH93_RS01110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XH93_RS01115	COG2835	tetraacyldisaccharide 4'-kinase activity
XH93_RS01130	COG1024	Enoyl-CoA hydratase
XH93_RS01145	COG3300	MHYT domain
XH93_RS01145	COG5001	Diguanylate cyclase
XH93_RS01160	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
XH93_RS01195	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XH93_RS01225	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS01230	COG2814	Major facilitator Superfamily
XH93_RS01235	COG0405	Gamma-glutamyltransferase
XH93_RS01245	COG3385	transposase activity
XH93_RS01250	COG0138	bifunctional purine biosynthesis protein purh
XH93_RS01275	COG1376	ErfK ybiS ycfS ynhG family protein
XH93_RS01280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XH93_RS01300	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XH93_RS01305	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XH93_RS01330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XH93_RS01345	COG2814	Major facilitator Superfamily
XH93_RS01370	COG4221	oxidoreductase activity
XH93_RS01375	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XH93_RS01380	COG1024	Enoyl-CoA hydratase
XH93_RS01395	COG1872	DUF167
XH93_RS01400	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XH93_RS01405	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XH93_RS01410	COG1247	-acetyltransferase
XH93_RS01425	COG3011	Protein conserved in bacteria
XH93_RS01435	COG1217	gtp-binding protein TYPA
XH93_RS01460	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XH93_RS01485	COG2154	pterin-4-alpha-carbinolamine dehydratase
XH93_RS01500	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS01510	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XH93_RS01520	COG0671	phosphoesterase, PA-phosphatase related
XH93_RS01525	COG0137	argininosuccinate synthase activity
XH93_RS01560	COG4178	(ABC) transporter
XH93_RS01600	COG2009	succinate dehydrogenase
XH93_RS01605	COG0583	DNA-binding transcription factor activity
XH93_RS01615	COG0730	response to heat
XH93_RS01625	COG0318	PFAM AMP-dependent synthetase and ligase
XH93_RS01630	COG4221	oxidoreductase activity
XH93_RS01635	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XH93_RS01640	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
XH93_RS01645	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XH93_RS01650	COG0477	Major facilitator Superfamily
XH93_RS01655	COG0473	3-isopropylmalate dehydrogenase activity
XH93_RS01670	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XH93_RS01675	COG2862	Uncharacterized protein family, UPF0114
XH93_RS01685	COG0288	reversible hydration of carbon dioxide
XH93_RS01690	COG2301	Belongs to the HpcH HpaI aldolase family
XH93_RS01705	COG0066	3-isopropylmalate dehydratase activity
XH93_RS01745	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XH93_RS01750	COG0335	large ribosomal subunit rRNA binding
XH93_RS01755	COG0336	Belongs to the RNA methyltransferase TrmD family
XH93_RS01770	COG0583	DNA-binding transcription factor activity
XH93_RS01775	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XH93_RS01780	COG0228	four-way junction DNA binding
XH93_RS01785	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XH93_RS01805	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XH93_RS01810	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XH93_RS01820	COG0564	pseudouridine synthase activity
XH93_RS01825	COG0552	protein localization to endoplasmic reticulum
XH93_RS01830	COG2917	probably involved in intracellular septation
XH93_RS01835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XH93_RS01845	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XH93_RS01850	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XH93_RS01855	COG4133	protoheme IX ABC transporter activity
XH93_RS01860	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
XH93_RS01880	COG0670	Belongs to the BI1 family
XH93_RS01885	COG1136	(ABC) transporter
XH93_RS01885	COG0577	efflux transmembrane transporter activity
XH93_RS01890	COG4181	ATPase activity
XH93_RS01900	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
XH93_RS01905	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XH93_RS01910	COG0039	L-malate dehydrogenase activity
XH93_RS01915	COG0045	succinate-CoA ligase (ADP-forming) activity
XH93_RS01925	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XH93_RS01935	COG0508	dehydrogenase complex catalyzes the overall conversion of
XH93_RS01940	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS01945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XH93_RS01960	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XH93_RS01970	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XH93_RS01975	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XH93_RS01980	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XH93_RS01985	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XH93_RS01990	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XH93_RS01995	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XH93_RS02005	COG0494	nUDIX hydrolase
XH93_RS02010	COG1051	belongs to the nudix hydrolase family
XH93_RS02020	COG0793	Belongs to the peptidase S41A family
XH93_RS02030	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XH93_RS02035	COG0799	negative regulation of ribosome biogenesis
XH93_RS02040	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XH93_RS02045	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XH93_RS02050	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XH93_RS02055	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XH93_RS02070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XH93_RS02075	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XH93_RS02080	COG0261	This protein binds to 23S rRNA in the presence of protein L20
XH93_RS02105	COG2827	Endonuclease containing a URI domain
XH93_RS02115	COG0488	(ABC) transporter
XH93_RS02120	COG0443	Heat shock 70 kDa protein
XH93_RS02130	COG0583	DNA-binding transcription factor activity
XH93_RS02135	COG2814	Major facilitator Superfamily
XH93_RS02145	COG2072	flavoprotein involved in K transport
XH93_RS02170	COG3220	belongs to the UPF0276 family
XH93_RS02180	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XH93_RS02195	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XH93_RS02200	COG1472	Belongs to the glycosyl hydrolase 3 family
XH93_RS02215	COG2197	response regulator
XH93_RS02240	COG0784	Response regulator, receiver
XH93_RS02240	COG0643	Histidine kinase
XH93_RS02240	COG2198	Histidine kinase
XH93_RS02245	COG0835	chemotaxis
XH93_RS02265	COG4566	intracellular signal transduction
XH93_RS02275	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XH93_RS02285	COG1178	ABC-type Fe3 transport system permease component
XH93_RS02295	COG3842	ATPase activity
XH93_RS02300	COG2827	Endonuclease containing a URI domain
XH93_RS02305	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XH93_RS02350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XH93_RS02360	COG0747	negative chemotaxis
XH93_RS02370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH93_RS02410	COG2084	Dehydrogenase
XH93_RS02420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XH93_RS02435	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
XH93_RS02440	COG0179	Fumarylacetoacetate (FAA) hydrolase
XH93_RS02445	COG3813	Protein conserved in bacteria
XH93_RS02450	COG1522	sequence-specific DNA binding
XH93_RS02460	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH93_RS02500	COG2205	protein histidine kinase activity
XH93_RS02520	COG0477	Major facilitator Superfamily
XH93_RS02530	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
XH93_RS02545	COG1278	Cold shock
XH93_RS02550	COG0828	Belongs to the bacterial ribosomal protein bS21 family
XH93_RS02560	COG0071	Belongs to the small heat shock protein (HSP20) family
XH93_RS02565	COG0071	Belongs to the small heat shock protein (HSP20) family
XH93_RS02575	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XH93_RS02605	COG1960	acyl-CoA dehydrogenase activity
XH93_RS02630	COG3474	cytochrome
XH93_RS02685	COG0437	4 iron, 4 sulfur cluster binding
XH93_RS02705	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XH93_RS02735	COG0829	nickel cation binding
XH93_RS02740	COG0831	urea catabolic process
XH93_RS02745	COG0832	Belongs to the urease beta subunit family
XH93_RS02750	COG0804	urea catabolic process
XH93_RS02755	COG0830	nickel cation binding
XH93_RS02760	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
XH93_RS02775	COG4191	Histidine kinase
XH93_RS02780	COG4191	Histidine kinase
XH93_RS02830	COG4566	intracellular signal transduction
XH93_RS02840	COG0604	alcohol dehydrogenase
XH93_RS02840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XH93_RS02840	COG3321	synthase
XH93_RS02840	COG4221	oxidoreductase activity
XH93_RS02850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XH93_RS02875	COG0850	regulation of cytokinetic process
XH93_RS02880	COG2894	cell division
XH93_RS02885	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XH93_RS02895	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XH93_RS02905	COG1522	sequence-specific DNA binding
XH93_RS02910	COG2515	1-aminocyclopropane-1-carboxylate deaminase
XH93_RS02915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XH93_RS02920	COG1408	metallophosphoesterase
XH93_RS02925	COG2072	flavoprotein involved in K transport
XH93_RS02930	COG0653	protein targeting
XH93_RS02945	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XH93_RS02945	COG2010	Cytochrome c
XH93_RS02950	COG2080	2 iron, 2 sulfur cluster binding
XH93_RS02955	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XH93_RS02955	COG2010	Cytochrome c
XH93_RS03025	COG1960	acyl-CoA dehydrogenase activity
XH93_RS03050	COG3246	L-lysine catabolic process to acetate
XH93_RS03055	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XH93_RS03065	COG4608	Belongs to the ABC transporter superfamily
XH93_RS03070	COG0444	Belongs to the ABC transporter superfamily
XH93_RS03075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH93_RS03080	COG0601	transmembrane transport
XH93_RS03115	COG0456	acetyltransferase
XH93_RS03115	COG0454	-acetyltransferase
XH93_RS03140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XH93_RS03155	COG1737	Transcriptional regulator
XH93_RS03165	COG3788	relative of glutathione S-transferase, MAPEG superfamily
XH93_RS03175	COG0577	efflux transmembrane transporter activity
XH93_RS03180	COG1136	(ABC) transporter
XH93_RS03190	COG2271	Major facilitator Superfamily
XH93_RS03195	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
XH93_RS03205	COG2271	Major facilitator Superfamily
XH93_RS03225	COG4771	TonB-dependent receptor
XH93_RS03230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XH93_RS03235	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
XH93_RS03245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XH93_RS03250	COG0737	Belongs to the 5'-nucleotidase family
XH93_RS03260	COG3258	Cytochrome c
XH93_RS03285	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XH93_RS03295	COG2814	Major facilitator Superfamily
XH93_RS03305	COG2514	catechol 2,3-dioxygenase activity
XH93_RS03315	COG1960	acyl-CoA dehydrogenase activity
XH93_RS03320	COG1960	acyl-CoA dehydrogenase activity
XH93_RS03325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XH93_RS03340	COG1294	oxidase, subunit
XH93_RS03345	COG1271	oxidase subunit
XH93_RS03360	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XH93_RS03370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XH93_RS03380	COG0583	DNA-binding transcription factor activity
XH93_RS03400	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
XH93_RS03405	COG1643	Atp-dependent helicase
XH93_RS03410	COG3577	Aspartyl protease
XH93_RS03425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XH93_RS03430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XH93_RS03435	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XH93_RS03450	COG0840	transmembrane signaling receptor activity
XH93_RS03460	COG1522	sequence-specific DNA binding
XH93_RS03465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XH93_RS03485	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
XH93_RS03490	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XH93_RS03495	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
XH93_RS03505	COG2223	nitrite transmembrane transporter activity
XH93_RS03515	COG0242	peptide deformylase activity
XH93_RS03520	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XH93_RS03525	COG0101	tRNA pseudouridine synthase activity
XH93_RS03530	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XH93_RS03540	COG2171	N-acyltransferase activity
XH93_RS03555	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XH93_RS03570	COG0706	membrane insertase activity
XH93_RS03580	COG0230	Belongs to the bacterial ribosomal protein bL34 family
XH93_RS03595	COG0583	DNA-binding transcription factor activity
XH93_RS03620	COG0318	PFAM AMP-dependent synthetase and ligase
XH93_RS03645	COG1960	acyl-CoA dehydrogenase activity
XH93_RS03670	COG4585	Histidine kinase
XH93_RS03675	COG2197	response regulator
XH93_RS03705	COG1970	mechanosensitive ion channel activity
XH93_RS03715	COG2226	methyltransferase
XH93_RS03720	COG1959	2 iron, 2 sulfur cluster binding
XH93_RS03740	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XH93_RS03745	COG0668	transmembrane transport
XH93_RS03755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XH93_RS03780	COG0513	Belongs to the DEAD box helicase family
XH93_RS03785	COG3284	Transcriptional regulator
XH93_RS03790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XH93_RS03810	COG2188	Transcriptional regulator
XH93_RS03815	COG0673	inositol 2-dehydrogenase activity
XH93_RS03820	COG2084	Dehydrogenase
XH93_RS03825	COG3181	Tripartite tricarboxylate transporter family receptor
XH93_RS03835	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
XH93_RS03840	COG2309	aminopeptidase activity
XH93_RS03845	COG0454	-acetyltransferase
XH93_RS03845	COG0456	acetyltransferase
XH93_RS03860	COG0789	Transcriptional regulator
XH93_RS03865	COG0667	Aldo Keto reductase
XH93_RS03870	COG0697	spore germination
XH93_RS03910	COG3853	Toxic anion resistance protein (TelA)
XH93_RS03920	COG4555	ABC transporter
XH93_RS03945	COG1022	Amp-dependent synthetase and ligase
XH93_RS03975	COG0747	negative chemotaxis
XH93_RS03980	COG0747	negative chemotaxis
XH93_RS03985	COG0601	transmembrane transport
XH93_RS03990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH93_RS03995	COG4608	Belongs to the ABC transporter superfamily
XH93_RS04005	COG0154	amidase activity
XH93_RS04015	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
XH93_RS04020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XH93_RS04025	COG1546	Belongs to the CinA family
XH93_RS04025	COG1058	Belongs to the CinA family
XH93_RS04055	COG1053	succinate dehydrogenase
XH93_RS04065	COG0583	DNA-binding transcription factor activity
XH93_RS04080	COG1024	Enoyl-CoA hydratase
XH93_RS04090	COG1960	acyl-CoA dehydrogenase activity
XH93_RS04095	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
XH93_RS04105	COG0154	amidase activity
XH93_RS04115	COG2267	carboxylic ester hydrolase activity
XH93_RS04130	COG0183	Belongs to the thiolase family
XH93_RS04150	COG3320	Male sterility
XH93_RS04150	COG1022	Amp-dependent synthetase and ligase
XH93_RS04155	COG1960	acyl-CoA dehydrogenase activity
XH93_RS04160	COG1960	acyl-CoA dehydrogenase activity
XH93_RS04165	COG1960	acyl-CoA dehydrogenase activity
XH93_RS04170	COG0778	Nitroreductase
XH93_RS04175	COG2378	regulation of single-species biofilm formation
XH93_RS04190	COG1024	Enoyl-CoA hydratase
XH93_RS04195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XH93_RS04265	COG1393	Belongs to the ArsC family
XH93_RS04380	COG1024	Enoyl-CoA hydratase
XH93_RS04385	COG0318	PFAM AMP-dependent synthetase and ligase
XH93_RS04480	COG0318	PFAM AMP-dependent synthetase and ligase
XH93_RS04485	COG1960	acyl-CoA dehydrogenase activity
XH93_RS04490	COG1960	acyl-CoA dehydrogenase activity
XH93_RS04495	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS04505	COG0717	Belongs to the dCTP deaminase family
XH93_RS04535	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
XH93_RS04535	COG2169	Transcriptional regulator
XH93_RS04550	COG1902	pentaerythritol trinitrate reductase activity
XH93_RS04585	COG1595	DNA-templated transcription, initiation
XH93_RS04620	COG0251	oxidation-reduction process
XH93_RS04650	COG1999	signal sequence binding
XH93_RS04660	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
XH93_RS04685	COG0167	dihydroorotate dehydrogenase activity
XH93_RS04690	COG0534	Mate efflux family protein
XH93_RS04695	COG1234	tRNA 3'-trailer cleavage
XH93_RS04725	COG1201	RNA secondary structure unwinding
XH93_RS04735	COG0583	DNA-binding transcription factor activity
XH93_RS04740	COG0697	spore germination
XH93_RS04760	COG0730	response to heat
XH93_RS04785	COG1960	acyl-CoA dehydrogenase activity
XH93_RS04790	COG0183	Belongs to the thiolase family
XH93_RS04795	COG1250	3-hydroxyacyl-CoA dehydrogenase
XH93_RS04795	COG1024	Enoyl-CoA hydratase
XH93_RS04805	COG0625	glutathione transferase activity
XH93_RS04835	COG0681	Belongs to the peptidase S26 family
XH93_RS04840	COG0312	modulator of DNA gyrase
XH93_RS04850	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XH93_RS04850	COG1565	acr, cog1565
XH93_RS04855	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XH93_RS04860	COG0109	protoheme IX farnesyltransferase activity
XH93_RS04870	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XH93_RS04885	COG3346	SURF1 family
XH93_RS04910	COG2059	Chromate
XH93_RS04930	COG0612	Peptidase, M16
XH93_RS04935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XH93_RS04945	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XH93_RS04950	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XH93_RS04960	COG0356	it plays a direct role in the translocation of protons across the membrane
XH93_RS04980	COG0432	Pfam Uncharacterised protein family UPF0047
XH93_RS04985	COG0477	Major facilitator Superfamily
XH93_RS04995	COG0784	Response regulator, receiver
XH93_RS04995	COG2205	protein histidine kinase activity
XH93_RS04995	COG2198	Histidine kinase
XH93_RS05000	COG0156	8-amino-7-oxononanoate synthase activity
XH93_RS05015	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
XH93_RS05035	COG0492	ferredoxin-NADP+ reductase activity
XH93_RS05070	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XH93_RS05075	COG5328	Belongs to the UPF0262 family
XH93_RS05080	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XH93_RS05085	COG0424	maF-like protein
XH93_RS05090	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
XH93_RS05145	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
XH93_RS05150	COG1196	nuclear chromosome segregation
XH93_RS05160	COG0641	radical SAM
XH93_RS05190	COG1475	DNA binding
XH93_RS05200	COG1250	3-hydroxyacyl-CoA dehydrogenase
XH93_RS05200	COG1024	Enoyl-CoA hydratase
XH93_RS05210	COG0589	response to stress
XH93_RS05230	COG0582	viral genome integration into host DNA
XH93_RS05245	COG2207	Transcriptional regulator
XH93_RS05300	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
XH93_RS05320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XH93_RS05360	COG0640	Transcriptional regulator
XH93_RS05370	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS05375	COG2267	carboxylic ester hydrolase activity
XH93_RS05395	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
XH93_RS05410	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
XH93_RS05420	COG0667	Aldo Keto reductase
XH93_RS05430	COG0494	nUDIX hydrolase
XH93_RS05470	COG2358	TRAP transporter, solute receptor (TAXI family
XH93_RS05485	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS05490	COG0025	NhaP-type Na H and K H
XH93_RS05505	COG5433	transposase activity
XH93_RS05520	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XH93_RS05525	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
XH93_RS05530	COG0328	RNA-DNA hybrid ribonuclease activity
XH93_RS05535	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
XH93_RS05535	COG0678	peroxiredoxin activity
XH93_RS05545	COG0318	PFAM AMP-dependent synthetase and ligase
XH93_RS05550	COG1686	Belongs to the peptidase S11 family
XH93_RS05555	COG1132	(ABC) transporter
XH93_RS05575	COG0140	phosphoribosyl-ATP diphosphatase activity
XH93_RS05580	COG1238	metal cluster binding
XH93_RS05610	COG0318	PFAM AMP-dependent synthetase and ligase
XH93_RS05660	COG0508	dehydrogenase complex catalyzes the overall conversion of
XH93_RS05665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XH93_RS05670	COG1301	dicarboxylic acid transport
XH93_RS05675	COG0183	Belongs to the thiolase family
XH93_RS05685	COG0281	malic enzyme
XH93_RS05685	COG0280	phosphate acetyltransferase
XH93_RS05690	COG1252	NADH dehydrogenase
XH93_RS05700	COG2204	response regulator
XH93_RS05705	COG3243	poly(R)-hydroxyalkanoic acid synthase
XH93_RS05710	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
XH93_RS05720	COG3395	kinase activity
XH93_RS05725	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XH93_RS05730	COG1349	DNA-binding transcription factor activity
XH93_RS05795	COG0154	amidase activity
XH93_RS05805	COG1012	belongs to the aldehyde dehydrogenase family
XH93_RS05815	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XH93_RS05865	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XH93_RS05865	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
XH93_RS05895	COG0583	DNA-binding transcription factor activity
XH93_RS05900	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS05910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XH93_RS05965	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XH93_RS05980	COG0483	inositol monophosphate 1-phosphatase activity
XH93_RS05995	COG3588	fructose-bisphosphate aldolase
XH93_RS06005	COG0126	phosphoglycerate kinase activity
XH93_RS06025	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
XH93_RS06040	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XH93_RS06045	COG1692	metallophosphoesterase
XH93_RS06055	COG0840	transmembrane signaling receptor activity
XH93_RS06060	COG0217	transcriptional regulatory protein
XH93_RS06065	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
XH93_RS06070	COG0632	four-way junction helicase activity
XH93_RS06075	COG2255	four-way junction helicase activity
XH93_RS06080	COG1408	metallophosphoesterase
XH93_RS06085	COG0824	Thioesterase
XH93_RS06100	COG0625	glutathione transferase activity
XH93_RS06105	COG1309	transcriptional regulator
XH93_RS06130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XH93_RS06140	COG3795	YCII-related domain
XH93_RS06145	COG4941	Belongs to the sigma-70 factor family
XH93_RS06170	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XH93_RS06180	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
XH93_RS06195	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS06235	COG1045	serine acetyltransferase
XH93_RS06245	COG1108	ABC-type Mn2 Zn2 transport systems permease components
XH93_RS06250	COG0803	Belongs to the bacterial solute-binding protein 9 family
XH93_RS06255	COG0523	cobalamin synthesis protein
XH93_RS06275	COG4689	acetoacetate decarboxylase
XH93_RS06290	COG0251	oxidation-reduction process
XH93_RS06315	COG0339	signal peptide processing
XH93_RS06325	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
XH93_RS06335	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XH93_RS06340	COG0330	HflC and HflK could
XH93_RS06375	COG0067	glutamate synthase
XH93_RS06375	COG0069	glutamate synthase activity
XH93_RS06375	COG0070	glutamate synthase
XH93_RS06385	COG0071	Belongs to the small heat shock protein (HSP20) family
XH93_RS06455	COG0583	DNA-binding transcription factor activity
XH93_RS06475	COG0483	inositol monophosphate 1-phosphatase activity
XH93_RS06530	COG0583	DNA-binding transcription factor activity
XH93_RS06545	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XH93_RS06560	COG2146	nitrite reductase [NAD(P)H] activity
XH93_RS06570	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XH93_RS06580	COG1309	transcriptional regulator
XH93_RS06665	COG1012	belongs to the aldehyde dehydrogenase family
XH93_RS06670	COG2005	Transcriptional regulator
XH93_RS06675	COG1902	pentaerythritol trinitrate reductase activity
XH93_RS06735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XH93_RS06740	COG0765	amino acid transport
XH93_RS06745	COG0765	amino acid transport
XH93_RS06750	COG1126	abc transporter atp-binding protein
XH93_RS06760	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XH93_RS06780	COG0583	DNA-binding transcription factor activity
XH93_RS06820	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
XH93_RS06850	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XH93_RS06885	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XH93_RS06900	COG0584	glycerophosphoryl diester phosphodiesterase
XH93_RS06930	COG0655	NAD(P)H dehydrogenase (quinone) activity
XH93_RS06935	COG1741	Belongs to the pirin family
XH93_RS06945	COG0583	DNA-binding transcription factor activity
XH93_RS06960	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XH93_RS06980	COG0257	Belongs to the bacterial ribosomal protein bL36 family
XH93_RS07005	COG2267	carboxylic ester hydrolase activity
XH93_RS07010	COG0028	Belongs to the TPP enzyme family
XH93_RS07015	COG3474	cytochrome
XH93_RS07020	COG0277	FAD linked oxidase domain protein
XH93_RS07025	COG0109	protoheme IX farnesyltransferase activity
XH93_RS07045	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XH93_RS07050	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XH93_RS07070	COG0640	Transcriptional regulator
XH93_RS07075	COG0277	FAD linked oxidase domain protein
XH93_RS07080	COG0247	lactate metabolic process
XH93_RS07100	COG4178	(ABC) transporter
XH93_RS07105	COG1620	l-lactate permease
XH93_RS07140	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
XH93_RS07140	COG2169	Transcriptional regulator
XH93_RS07160	COG0542	response to heat
XH93_RS07185	COG0459	protein refolding
XH93_RS07190	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XH93_RS07205	COG1376	ErfK ybiS ycfS ynhG family protein
XH93_RS07205	COG1388	LysM domain
XH93_RS07210	COG3416	Protein conserved in bacteria
XH93_RS07220	COG0463	Glycosyl transferase, family 2
XH93_RS07230	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
XH93_RS07245	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XH93_RS07255	COG0312	modulator of DNA gyrase
XH93_RS07260	COG0483	inositol monophosphate 1-phosphatase activity
XH93_RS07275	COG1519	Transferase
XH93_RS07280	COG1663	tetraacyldisaccharide 4'-kinase activity
XH93_RS07295	COG1570	exodeoxyribonuclease VII activity
XH93_RS07300	COG0151	Belongs to the GarS family
XH93_RS07310	COG1960	acyl-CoA dehydrogenase activity
XH93_RS07315	COG0596	Alpha beta hydrolase
XH93_RS07320	COG0590	tRNA wobble adenosine to inosine editing
XH93_RS07325	COG1187	pseudouridine synthase activity
XH93_RS07330	COG0742	ribosomal rna small subunit methyltransferase
XH93_RS07335	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XH93_RS07375	COG0612	Peptidase, M16
XH93_RS07380	COG0612	Peptidase, M16
XH93_RS07390	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XH93_RS07395	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
XH93_RS07410	COG0196	riboflavin kinase activity
XH93_RS07415	COG0745	RESPONSE REGULATOR receiver
XH93_RS07430	COG2890	protein-(glutamine-N5) methyltransferase activity
XH93_RS07435	COG0314	molybdopterin synthase activity
XH93_RS07445	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XH93_RS07450	COG0322	excinuclease ABC activity
XH93_RS07460	COG1278	Cold shock
XH93_RS07465	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XH93_RS07490	COG2205	protein histidine kinase activity
XH93_RS07495	COG0745	RESPONSE REGULATOR receiver
XH93_RS07500	COG1846	Transcriptional regulator
XH93_RS07505	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XH93_RS07515	COG0124	histidyl-tRNA synthetase
XH93_RS07520	COG1942	4-Oxalocrotonate Tautomerase
XH93_RS07540	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XH93_RS07545	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS07555	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XH93_RS07565	COG1496	oxidoreductase activity
XH93_RS07575	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XH93_RS07595	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XH93_RS07600	COG0193	aminoacyl-tRNA hydrolase activity
XH93_RS07605	COG0012	GTP binding
XH93_RS07610	COG1937	Protein conserved in bacteria
XH93_RS07620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XH93_RS07625	COG0583	DNA-binding transcription factor activity
XH93_RS07635	COG1522	sequence-specific DNA binding
XH93_RS07645	COG2259	Doxx family
XH93_RS07655	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XH93_RS07660	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XH93_RS07695	COG0505	Belongs to the CarA family
XH93_RS07710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XH93_RS07745	COG0640	Transcriptional regulator
XH93_RS07760	COG1280	lysine exporter protein (LysE YggA)
XH93_RS07765	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XH93_RS07795	COG4689	acetoacetate decarboxylase
XH93_RS07805	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS07835	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS07850	COG1181	Belongs to the D-alanine--D-alanine ligase family
XH93_RS07900	COG1414	Transcriptional regulator
XH93_RS07915	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XH93_RS07920	COG5433	transposase activity
XH93_RS07980	COG1280	lysine exporter protein (LysE YggA)
XH93_RS07985	COG5001	Diguanylate cyclase
XH93_RS07985	COG4251	negative regulation of phosphorylation
XH93_RS07985	COG3706	GGDEF domain
XH93_RS07985	COG2203	Gaf domain
XH93_RS08000	COG1376	ErfK ybiS ycfS ynhG family protein
XH93_RS08005	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XH93_RS08010	COG0564	pseudouridine synthase activity
XH93_RS08020	COG0723	plastoquinol--plastocyanin reductase activity
XH93_RS08095	COG4680	protein conserved in bacteria
XH93_RS08155	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XH93_RS08160	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XH93_RS08165	COG0156	8-amino-7-oxononanoate synthase activity
XH93_RS08170	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XH93_RS08175	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XH93_RS08195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XH93_RS08205	COG2223	nitrite transmembrane transporter activity
XH93_RS08210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XH93_RS08225	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XH93_RS08250	COG4566	intracellular signal transduction
XH93_RS08255	COG4566	intracellular signal transduction
XH93_RS08260	COG4191	Histidine kinase
XH93_RS08265	COG1301	dicarboxylic acid transport
XH93_RS08285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XH93_RS08300	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
XH93_RS08305	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
XH93_RS08310	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
XH93_RS08315	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
XH93_RS08320	COG0298	carbon dioxide binding
XH93_RS08330	COG1773	rubredoxin
XH93_RS08340	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
XH93_RS08345	COG0375	protein maturation
XH93_RS08350	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
XH93_RS08365	COG0409	Hydrogenase expression formation protein
XH93_RS08370	COG0309	Hydrogenase expression formation protein (HypE)
XH93_RS08375	COG0686	Belongs to the AlaDH PNT family
XH93_RS08380	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XH93_RS08385	COG0719	Fe-S assembly protein
XH93_RS08390	COG0396	ATPase activity
XH93_RS08395	COG0719	Fe-S assembly protein
XH93_RS08400	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XH93_RS08410	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
XH93_RS08415	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
XH93_RS08420	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
XH93_RS08435	COG5420	small protein containing a coiled-coil domain
XH93_RS08455	COG1484	DNA-dependent DNA replication
XH93_RS08460	COG4584	PFAM Integrase catalytic
XH93_RS08480	COG0316	Belongs to the HesB IscA family
XH93_RS08490	COG1104	cysteine desulfurase activity
XH93_RS08495	COG5554	nitrogen fixation
XH93_RS08505	COG0535	radical SAM domain protein
XH93_RS08510	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XH93_RS08520	COG5554	nitrogen fixation
XH93_RS08540	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XH93_RS08555	COG3411	Ferredoxin
XH93_RS08560	COG3047	cAMP biosynthetic process
XH93_RS08600	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
XH93_RS08605	COG0644	oxidoreductase
XH93_RS08610	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
XH93_RS08615	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XH93_RS08620	COG0450	alkyl hydroperoxide reductase
XH93_RS08625	COG1618	nucleotide phosphatase activity, acting on free nucleotides
XH93_RS08625	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XH93_RS08630	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XH93_RS08670	COG4886	Leucine-rich repeat (LRR) protein
XH93_RS08700	COG5010	COG0457 FOG TPR repeat
XH93_RS08705	COG4789	Type iii secretion
XH93_RS08740	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XH93_RS08740	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XH93_RS08770	COG4669	(LipO)protein
XH93_RS08780	COG1317	bacterial-type flagellum organization
XH93_RS08785	COG1157	protein secretion by the type III secretion system
XH93_RS08795	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
XH93_RS08800	COG4790	Type iii secretion
XH93_RS08805	COG4794	Type iii secretion
XH93_RS08810	COG4791	protein targeting
XH93_RS08815	COG4792	protein secretion
XH93_RS08820	COG5461	TIGRFAM pilus (Caulobacter type) biogenesis lipoprotein CpaD
XH93_RS08825	COG4964	Belongs to the GSP D family
XH93_RS08830	COG0745	RESPONSE REGULATOR receiver
XH93_RS08850	COG2264	protein methyltransferase activity
XH93_RS08900	COG5265	(ABC) transporter
XH93_RS08940	COG4691	Plasmid stability protein
XH93_RS08955	COG3620	sequence-specific DNA binding
XH93_RS08960	COG3550	peptidyl-serine autophosphorylation
XH93_RS09000	COG2124	cytochrome p450
XH93_RS09010	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS09015	COG2124	cytochrome p450
XH93_RS09020	COG0142	geranyltranstransferase activity
XH93_RS09025	COG1657	PFAM Prenyltransferase squalene oxidase
XH93_RS09055	COG1448	Aminotransferase
XH93_RS09075	COG0459	protein refolding
XH93_RS09080	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XH93_RS09140	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XH93_RS09150	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XH93_RS09155	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XH93_RS09160	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XH93_RS09170	COG0454	-acetyltransferase
XH93_RS09205	COG1129	ABC transporter
XH93_RS09210	COG1172	Belongs to the binding-protein-dependent transport system permease family
XH93_RS09225	COG0367	asparagine synthase
XH93_RS09255	COG1522	sequence-specific DNA binding
XH93_RS09260	COG1012	belongs to the aldehyde dehydrogenase family
XH93_RS09265	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XH93_RS09275	COG2843	Capsule synthesis protein
XH93_RS09280	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XH93_RS09295	COG1473	amidohydrolase
XH93_RS09310	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
XH93_RS09315	COG2197	response regulator
XH93_RS09360	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XH93_RS09380	COG5632	N-Acetylmuramoyl-L-alanine amidase
XH93_RS09380	COG3409	Peptidoglycan-binding domain 1 protein
XH93_RS09410	COG0667	Aldo Keto reductase
XH93_RS09420	COG3318	Belongs to the UPF0149 family
XH93_RS09425	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
XH93_RS09445	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XH93_RS09450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XH93_RS09460	COG1126	abc transporter atp-binding protein
XH93_RS09490	COG0318	PFAM AMP-dependent synthetase and ligase
XH93_RS09500	COG1024	Enoyl-CoA hydratase
XH93_RS09505	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XH93_RS09510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XH93_RS09520	COG4584	PFAM Integrase catalytic
XH93_RS09525	COG1484	DNA-dependent DNA replication
XH93_RS09530	COG0583	DNA-binding transcription factor activity
XH93_RS09540	COG4372	Transposase
XH93_RS09545	COG3436	PFAM IS66 Orf2 family protein
XH93_RS09560	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XH93_RS09570	COG3436	PFAM IS66 Orf2 family protein
XH93_RS09575	COG2963	transposase activity
XH93_RS09605	COG0318	PFAM AMP-dependent synthetase and ligase
XH93_RS09625	COG4584	PFAM Integrase catalytic
XH93_RS09630	COG1484	DNA-dependent DNA replication
XH93_RS09635	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XH93_RS09645	COG0765	amino acid transport
XH93_RS09650	COG0765	amino acid transport
XH93_RS09655	COG1126	abc transporter atp-binding protein
XH93_RS09685	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH93_RS09690	COG1960	acyl-CoA dehydrogenase activity
XH93_RS09700	COG1024	Enoyl-CoA hydratase
XH93_RS09715	COG3436	PFAM IS66 Orf2 family protein
XH93_RS09720	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XH93_RS09740	COG2433	Pfam Transposase IS66
XH93_RS09745	COG0583	DNA-binding transcription factor activity
XH93_RS09750	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XH93_RS09765	COG2963	transposase activity
XH93_RS09775	COG4584	PFAM Integrase catalytic
XH93_RS09780	COG1484	DNA-dependent DNA replication
XH93_RS09790	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS09795	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS09810	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XH93_RS09815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XH93_RS09820	COG0765	amino acid transport
XH93_RS09825	COG0765	amino acid transport
XH93_RS09830	COG1126	abc transporter atp-binding protein
XH93_RS09835	COG2814	Major facilitator Superfamily
XH93_RS09845	COG1802	Transcriptional regulator
XH93_RS09870	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
XH93_RS09890	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XH93_RS09930	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XH93_RS09935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XH93_RS09965	COG3436	PFAM IS66 Orf2 family protein
XH93_RS10000	COG1250	3-hydroxyacyl-CoA dehydrogenase
XH93_RS10000	COG1024	Enoyl-CoA hydratase
XH93_RS10005	COG0183	Belongs to the thiolase family
XH93_RS10010	COG2963	transposase activity
XH93_RS10020	COG0604	alcohol dehydrogenase
XH93_RS10075	COG0156	8-amino-7-oxononanoate synthase activity
XH93_RS10135	COG3436	PFAM IS66 Orf2 family protein
XH93_RS10145	COG4584	PFAM Integrase catalytic
XH93_RS10150	COG1484	DNA-dependent DNA replication
XH93_RS10160	COG0463	Glycosyl transferase, family 2
XH93_RS10175	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XH93_RS10210	COG1396	sequence-specific DNA binding
XH93_RS10250	COG1484	DNA-dependent DNA replication
XH93_RS10255	COG4584	PFAM Integrase catalytic
XH93_RS10260	COG0583	DNA-binding transcription factor activity
XH93_RS10280	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XH93_RS10290	COG0583	DNA-binding transcription factor activity
XH93_RS10300	COG0436	Aminotransferase
XH93_RS10315	COG3842	ATPase activity
XH93_RS10320	COG1175	transmembrane transport
XH93_RS10325	COG0395	ABC-type sugar transport system, permease component
XH93_RS10340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XH93_RS10365	COG3608	succinylglutamate desuccinylase aspartoacylase
XH93_RS10370	COG2226	methyltransferase
XH93_RS10380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XH93_RS10400	COG1213	nucleotidyl transferase
XH93_RS10435	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
XH93_RS10450	COG4584	PFAM Integrase catalytic
XH93_RS10465	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XH93_RS10475	COG1505	serine-type exopeptidase activity
XH93_RS10510	COG1278	Cold shock
XH93_RS10530	COG4886	Leucine-rich repeat (LRR) protein
XH93_RS10580	COG2255	four-way junction helicase activity
XH93_RS10615	COG5434	Belongs to the glycosyl hydrolase 28 family
XH93_RS10630	COG3594	Acyltransferase
XH93_RS10645	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XH93_RS10650	COG0730	response to heat
XH93_RS10660	COG2771	luxR family
XH93_RS10680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XH93_RS10725	COG1215	transferase activity, transferring glycosyl groups
XH93_RS10730	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XH93_RS10735	COG2192	nodulation
XH93_RS10740	COG1131	(ABC) transporter
XH93_RS10745	COG0842	Transport permease protein
XH93_RS10750	COG2192	nodulation
XH93_RS10765	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS10770	COG3604	Transcriptional regulator
XH93_RS10845	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XH93_RS10860	COG0464	growth
XH93_RS10910	COG0583	DNA-binding transcription factor activity
XH93_RS10915	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS10920	COG3959	Transketolase, thiamine diphosphate binding domain
XH93_RS10925	COG3958	Transketolase
XH93_RS10930	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XH93_RS10945	COG3842	ATPase activity
XH93_RS10950	COG0395	ABC-type sugar transport system, permease component
XH93_RS10955	COG1175	transmembrane transport
XH93_RS10985	COG1079	Belongs to the binding-protein-dependent transport system permease family
XH93_RS10990	COG3845	ABC transporter
XH93_RS11020	COG4191	Histidine kinase
XH93_RS11025	COG4566	intracellular signal transduction
XH93_RS11030	COG4566	intracellular signal transduction
XH93_RS11090	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XH93_RS11095	COG3657	addiction module killer protein
XH93_RS11190	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
XH93_RS11270	COG1841	ribosomal large subunit assembly
XH93_RS11295	COG1793	dna ligase
XH93_RS11360	COG0444	Belongs to the ABC transporter superfamily
XH93_RS11410	COG2086	electron transfer activity
XH93_RS11445	COG0318	PFAM AMP-dependent synthetase and ligase
XH93_RS11465	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XH93_RS11470	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XH93_RS11495	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XH93_RS11515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XH93_RS11520	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XH93_RS11535	COG0459	protein refolding
XH93_RS11540	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XH93_RS11545	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XH93_RS11560	COG3318	Belongs to the UPF0149 family
XH93_RS11565	COG2433	Pfam Transposase IS66
XH93_RS11570	COG3436	PFAM IS66 Orf2 family protein
XH93_RS11575	COG2963	transposase activity
XH93_RS11580	COG0275	rRNA processing
XH93_RS11625	COG2814	Major facilitator Superfamily
XH93_RS11655	COG5001	Diguanylate cyclase
XH93_RS11655	COG3300	MHYT domain
XH93_RS11660	COG5001	Diguanylate cyclase
XH93_RS11660	COG3300	MHYT domain
XH93_RS11685	COG0156	8-amino-7-oxononanoate synthase activity
XH93_RS11705	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
XH93_RS11750	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
XH93_RS11755	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XH93_RS11765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XH93_RS11775	COG4566	intracellular signal transduction
XH93_RS11780	COG4191	Histidine kinase
XH93_RS11800	COG3278	Belongs to the heme-copper respiratory oxidase family
XH93_RS11815	COG2010	Cytochrome c
XH93_RS11830	COG2217	Heavy metal translocating P-type atpase
XH93_RS11845	COG3551	Protein conserved in bacteria
XH93_RS11850	COG0175	sulfate reduction
XH93_RS11875	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XH93_RS11890	COG0174	glutamine synthetase
XH93_RS11915	COG5489	Protein of unknown function (DUF736)
XH93_RS11960	COG5489	Protein of unknown function (DUF736)
XH93_RS11980	COG0681	Belongs to the peptidase S26 family
XH93_RS11985	COG0741	lytic transglycosylase activity
XH93_RS11985	COG1196	nuclear chromosome segregation
XH93_RS11985	COG0739	heme binding
XH93_RS11995	COG4372	Transposase
XH93_RS12030	COG4962	Type ii secretion system protein e
XH93_RS12035	COG3838	Conjugal transfer protein Trbc
XH93_RS12045	COG3451	type IV secretory pathway VirB4
XH93_RS12075	COG2948	multi-organism process
XH93_RS12100	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
XH93_RS12105	COG0647	UMP catabolic process
XH93_RS12110	COG0747	negative chemotaxis
XH93_RS12115	COG0601	transmembrane transport
XH93_RS12120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH93_RS12130	COG0154	amidase activity
XH93_RS12135	COG3178	'Phosphotransferase
XH93_RS12155	COG1349	DNA-binding transcription factor activity
XH93_RS12160	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
XH93_RS12185	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XH93_RS12200	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
XH93_RS12205	COG2971	BadF BadG BcrA BcrD
XH93_RS12210	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XH93_RS12215	COG0527	aspartate kinase activity
XH93_RS12225	COG1522	sequence-specific DNA binding
XH93_RS12230	COG1464	Belongs to the NlpA lipoprotein family
XH93_RS12235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XH93_RS12240	COG2226	methyltransferase
XH93_RS12280	COG1960	acyl-CoA dehydrogenase activity
XH93_RS12290	COG1116	anion transmembrane transporter activity
XH93_RS12295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XH93_RS12300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XH93_RS12305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XH93_RS12310	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
XH93_RS12320	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XH93_RS12325	COG2011	ABC-type metal ion transport system permease component
XH93_RS12330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XH93_RS12355	COG1464	Belongs to the NlpA lipoprotein family
XH93_RS12375	COG0069	glutamate synthase activity
XH93_RS12380	COG2218	PFAM glutamate synthase alpha subunit domain protein
XH93_RS12385	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
XH93_RS12410	COG1137	ATPase activity
XH93_RS12445	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XH93_RS12460	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XH93_RS12460	COG0446	pyridine nucleotide-disulphide oxidoreductase
XH93_RS12470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XH93_RS12475	COG4977	sequence-specific DNA binding
XH93_RS12490	COG0831	urea catabolic process
XH93_RS12490	COG0832	Belongs to the urease beta subunit family
XH93_RS12495	COG0804	urea catabolic process
XH93_RS12500	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
XH93_RS12505	COG0829	nickel cation binding
XH93_RS12515	COG1175	transmembrane transport
XH93_RS12520	COG0395	ABC-type sugar transport system, permease component
XH93_RS12525	COG0584	glycerophosphoryl diester phosphodiesterase
XH93_RS12530	COG3540	Alkaline phosphatase
XH93_RS12535	COG2390	Transcriptional regulator
XH93_RS12540	COG1063	alcohol dehydrogenase
XH93_RS12560	COG1309	transcriptional regulator
XH93_RS12565	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS12580	COG4774	siderophore transport
XH93_RS12605	COG0297	glycogen (starch) synthase activity
XH93_RS12610	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
XH93_RS12625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XH93_RS12650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XH93_RS12655	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XH93_RS12665	COG4597	amino acid ABC transporter
XH93_RS12670	COG0765	amino acid transport
XH93_RS12675	COG2345	Transcriptional regulator
XH93_RS12730	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
XH93_RS12735	COG1335	isochorismatase
XH93_RS12740	COG0181	hydroxymethylbilane synthase activity
XH93_RS12745	COG1024	Enoyl-CoA hydratase
XH93_RS12750	COG4638	Rieske (2fe-2S)
XH93_RS12760	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
XH93_RS12765	COG3454	Phosphonate metabolism
XH93_RS12775	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
XH93_RS12780	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
XH93_RS12790	COG3639	organic phosphonate transmembrane transporter activity
XH93_RS12800	COG2188	Transcriptional regulator
XH93_RS12805	COG3624	Phosphonate C-P lyase system protein PhnG
XH93_RS12810	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
XH93_RS12815	COG3626	phosphonate metabolism
XH93_RS12820	COG3627	carbon phosphorus lyase activity
XH93_RS12825	COG4107	phosphonate C-P lyase system protein PhnK
XH93_RS12830	COG4778	phosphonate C-P lyase system protein PhnL
XH93_RS12835	COG3454	Phosphonate metabolism
XH93_RS12840	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
XH93_RS12850	COG1309	transcriptional regulator
XH93_RS12855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XH93_RS12870	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS12905	COG3964	amidohydrolase
XH93_RS12910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XH93_RS12930	COG1960	acyl-CoA dehydrogenase activity
XH93_RS12935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XH93_RS12945	COG0318	PFAM AMP-dependent synthetase and ligase
XH93_RS12955	COG1376	ErfK ybiS ycfS ynhG family protein
XH93_RS12970	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS12975	COG0259	pyridoxamine-phosphate oxidase activity
XH93_RS13005	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XH93_RS13025	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
XH93_RS13050	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XH93_RS13055	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
XH93_RS13065	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XH93_RS13070	COG1722	exodeoxyribonuclease VII activity
XH93_RS13075	COG0123	including yeast histone deacetylase and acetoin utilization protein
XH93_RS13080	COG1525	nuclease
XH93_RS13080	COG0737	Belongs to the 5'-nucleotidase family
XH93_RS13080	COG4085	toxin activity
XH93_RS13085	COG1024	Enoyl-CoA hydratase
XH93_RS13090	COG2080	2 iron, 2 sulfur cluster binding
XH93_RS13095	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XH93_RS13100	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XH93_RS13120	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XH93_RS13135	COG1960	acyl-CoA dehydrogenase activity
XH93_RS13165	COG1024	Enoyl-CoA hydratase
XH93_RS13170	COG0489	protein tyrosine kinase activity
XH93_RS13185	COG0477	Major facilitator Superfamily
XH93_RS13195	COG1609	Transcriptional regulator
XH93_RS13200	COG3260	NADH ubiquinone oxidoreductase 20
XH93_RS13205	COG0649	NAD binding
XH93_RS13210	COG0651	ATP synthesis coupled electron transport
XH93_RS13220	COG0650	Formate hydrogenlyase subunit 4
XH93_RS13225	COG0651	ATP synthesis coupled electron transport
XH93_RS13255	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS13270	COG1022	Amp-dependent synthetase and ligase
XH93_RS13320	COG3845	ABC transporter
XH93_RS13325	COG1335	isochorismatase
XH93_RS13330	COG1079	Belongs to the binding-protein-dependent transport system permease family
XH93_RS13335	COG1079	Belongs to the binding-protein-dependent transport system permease family
XH93_RS13360	COG2855	membrane
XH93_RS13365	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XH93_RS13370	COG1335	isochorismatase
XH93_RS13375	COG3833	ABC-type maltose transport systems, permease component
XH93_RS13380	COG1175	transmembrane transport
XH93_RS13385	COG1653	transport
XH93_RS13395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XH93_RS13405	COG1980	fructose-bisphosphate aldolase activity
XH93_RS13415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH93_RS13420	COG0601	transmembrane transport
XH93_RS13445	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XH93_RS13455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XH93_RS13475	COG1116	anion transmembrane transporter activity
XH93_RS13480	COG1960	acyl-CoA dehydrogenase activity
XH93_RS13490	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XH93_RS13525	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
XH93_RS13540	COG4948	Mandelate Racemase Muconate Lactonizing
XH93_RS13550	COG0444	Belongs to the ABC transporter superfamily
XH93_RS13570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH93_RS13600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XH93_RS13615	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
XH93_RS13620	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XH93_RS13620	COG2010	Cytochrome c
XH93_RS13625	COG2080	2 iron, 2 sulfur cluster binding
XH93_RS13710	COG0446	pyridine nucleotide-disulphide oxidoreductase
XH93_RS13725	COG2814	Major facilitator Superfamily
XH93_RS13730	COG4149	molybdate abc transporter
XH93_RS13735	COG1840	ABC-type Fe3 transport system, periplasmic component
XH93_RS13740	COG3842	ATPase activity
XH93_RS13770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XH93_RS13775	COG1309	transcriptional regulator
XH93_RS13785	COG2072	flavoprotein involved in K transport
XH93_RS13790	COG2015	COG2015, Alkyl sulfatase and related hydrolases
XH93_RS13800	COG1137	ATPase activity
XH93_RS13820	COG0438	transferase activity, transferring glycosyl groups
XH93_RS13825	COG1132	(ABC) transporter
XH93_RS13870	COG0583	DNA-binding transcription factor activity
XH93_RS13880	COG0297	glycogen (starch) synthase activity
XH93_RS13890	COG0747	negative chemotaxis
XH93_RS13895	COG0601	transmembrane transport
XH93_RS13900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH93_RS13905	COG0444	Belongs to the ABC transporter superfamily
XH93_RS13920	COG0473	3-isopropylmalate dehydrogenase activity
XH93_RS13930	COG1396	sequence-specific DNA binding
XH93_RS13940	COG1301	dicarboxylic acid transport
XH93_RS13945	COG2202	Pas domain
XH93_RS13945	COG3920	Histidine kinase
XH93_RS13955	COG3485	protocatechuate 3,4-dioxygenase
XH93_RS13960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XH93_RS13965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XH93_RS13970	COG1116	anion transmembrane transporter activity
XH93_RS14000	COG2814	Major facilitator Superfamily
XH93_RS14005	COG3485	protocatechuate 3,4-dioxygenase
XH93_RS14020	COG1012	belongs to the aldehyde dehydrogenase family
XH93_RS14025	COG0656	L-ascorbic acid biosynthetic process
XH93_RS14030	COG0697	spore germination
XH93_RS14040	COG1063	alcohol dehydrogenase
XH93_RS14045	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS14055	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS14060	COG0477	Major facilitator Superfamily
XH93_RS14065	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS14070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XH93_RS14075	COG0765	amino acid transport
XH93_RS14095	COG1522	sequence-specific DNA binding
XH93_RS14115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XH93_RS14130	COG0129	dihydroxy-acid dehydratase activity
XH93_RS14155	COG1024	Enoyl-CoA hydratase
XH93_RS14170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XH93_RS14180	COG1309	transcriptional regulator
XH93_RS14185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XH93_RS14205	COG0673	inositol 2-dehydrogenase activity
XH93_RS14220	COG1304	FMN binding
XH93_RS14230	COG2124	cytochrome p450
XH93_RS14240	COG0028	Belongs to the TPP enzyme family
XH93_RS14240	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
XH93_RS14250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XH93_RS14255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XH93_RS14265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH93_RS14270	COG0601	transmembrane transport
XH93_RS14280	COG4608	Belongs to the ABC transporter superfamily
XH93_RS14295	COG0405	Gamma-glutamyltransferase
XH93_RS14300	COG4608	Belongs to the ABC transporter superfamily
XH93_RS14305	COG0444	Belongs to the ABC transporter superfamily
XH93_RS14310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH93_RS14320	COG0747	negative chemotaxis
XH93_RS14330	COG2226	methyltransferase
XH93_RS14330	COG0596	Alpha beta hydrolase
XH93_RS14330	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XH93_RS14340	COG2267	carboxylic ester hydrolase activity
XH93_RS14345	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XH93_RS14345	COG2124	cytochrome p450
XH93_RS14375	COG0456	acetyltransferase
XH93_RS14390	COG2733	membrane
XH93_RS14395	COG0596	Alpha beta hydrolase
XH93_RS14400	COG3327	negative regulation of DNA-templated transcription, initiation
XH93_RS14405	COG3396	Phenylacetate-CoA oxygenase
XH93_RS14410	COG3460	Phenylacetate-CoA oxygenase
XH93_RS14415	COG3396	Phenylacetate-CoA oxygenase
XH93_RS14420	COG2151	metal-sulfur cluster biosynthetic enzyme
XH93_RS14425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XH93_RS14430	COG2050	protein possibly involved in aromatic compounds catabolism
XH93_RS14480	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XH93_RS14485	COG0477	Major facilitator Superfamily
XH93_RS14520	COG2070	2-Nitropropane dioxygenase
XH93_RS14525	COG1309	transcriptional regulator
XH93_RS14540	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS14570	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XH93_RS14580	COG0583	DNA-binding transcription factor activity
XH93_RS14585	COG4336	lyase activity
XH93_RS14605	COG1137	ATPase activity
XH93_RS14620	COG0235	Class ii aldolase
XH93_RS14625	COG2084	Dehydrogenase
XH93_RS14630	COG3622	Belongs to the hyi family
XH93_RS14635	COG3395	kinase activity
XH93_RS14660	COG2070	2-Nitropropane dioxygenase
XH93_RS14665	COG0625	glutathione transferase activity
XH93_RS14680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XH93_RS14685	COG1960	acyl-CoA dehydrogenase activity
XH93_RS14695	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS14700	COG1024	Enoyl-CoA hydratase
XH93_RS14715	COG1024	Enoyl-CoA hydratase
XH93_RS14720	COG1960	acyl-CoA dehydrogenase activity
XH93_RS14735	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS14740	COG1024	Enoyl-CoA hydratase
XH93_RS14750	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XH93_RS14755	COG3386	PFAM SMP-30 Gluconolaconase
XH93_RS14760	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS14790	COG3145	DNA-N1-methyladenine dioxygenase activity
XH93_RS14795	COG0028	Belongs to the TPP enzyme family
XH93_RS14800	COG0179	Fumarylacetoacetate (FAA) hydrolase
XH93_RS14810	COG1012	belongs to the aldehyde dehydrogenase family
XH93_RS14820	COG3971	2-oxopent-4-enoate hydratase activity
XH93_RS14825	COG1846	Transcriptional regulator
XH93_RS14840	COG0559	Belongs to the binding-protein-dependent transport system permease family
XH93_RS14855	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
XH93_RS14865	COG2721	sulfolactate sulfo-lyase activity
XH93_RS14885	COG2203	Gaf domain
XH93_RS14885	COG5001	Diguanylate cyclase
XH93_RS14885	COG4251	negative regulation of phosphorylation
XH93_RS14885	COG3706	GGDEF domain
XH93_RS14895	COG4303	Ethanolamine ammonia lyase large subunit
XH93_RS14905	COG4302	ethanolamine ammonia-lyase activity
XH93_RS14925	COG1562	ergosterol biosynthetic process
XH93_RS14930	COG1562	ergosterol biosynthetic process
XH93_RS14935	COG1233	COG1233 Phytoene dehydrogenase and related
XH93_RS14940	COG1657	PFAM Prenyltransferase squalene oxidase
XH93_RS14945	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
XH93_RS14950	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XH93_RS14955	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XH93_RS15020	COG1473	amidohydrolase
XH93_RS15030	COG0306	phosphate transporter
XH93_RS15035	COG1573	uracil-dna glycosylase
XH93_RS15050	COG0587	DNA-directed DNA polymerase activity
XH93_RS15060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH93_RS15090	COG1024	Enoyl-CoA hydratase
XH93_RS15150	COG4191	Histidine kinase
XH93_RS15150	COG0784	Response regulator, receiver
XH93_RS15160	COG0583	DNA-binding transcription factor activity
XH93_RS15180	COG1703	isobutyryl-CoA mutase activity
XH93_RS15205	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XH93_RS15215	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XH93_RS15230	COG0433	COG0433 Predicted ATPase
XH93_RS15240	COG1943	Transposase
XH93_RS15260	COG4957	zinc ion binding
XH93_RS15265	COG2166	iron-sulfur cluster assembly
XH93_RS15275	COG2205	protein histidine kinase activity
XH93_RS15330	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XH93_RS15335	COG2983	Belongs to the UPF0260 family
XH93_RS15370	COG0559	Belongs to the binding-protein-dependent transport system permease family
XH93_RS15380	COG1129	ABC transporter
XH93_RS15395	COG0028	Belongs to the TPP enzyme family
XH93_RS15405	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XH93_RS15405	COG1672	PFAM Archaeal ATPase
XH93_RS15420	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
XH93_RS15430	COG1088	dTDP-glucose 4,6-dehydratase activity
XH93_RS15435	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
XH93_RS15465	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
XH93_RS15470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XH93_RS15490	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
XH93_RS15495	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XH93_RS15530	COG0489	protein tyrosine kinase activity
XH93_RS15530	COG3206	protein involved in exopolysaccharide biosynthesis
XH93_RS15535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XH93_RS15560	COG1696	Membrane protein involved in D-alanine export
XH93_RS15570	COG1215	transferase activity, transferring glycosyl groups
XH93_RS15575	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XH93_RS15605	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XH93_RS15620	COG1215	transferase activity, transferring glycosyl groups
XH93_RS15660	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XH93_RS15670	COG0726	polysaccharide deacetylase
XH93_RS15675	COG1216	Glycosyl transferase, family 2
XH93_RS15680	COG1132	(ABC) transporter
XH93_RS15700	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XH93_RS15705	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XH93_RS15705	COG0662	Cupin 2, conserved barrel domain protein
XH93_RS15715	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XH93_RS15740	COG4235	cytochrome complex assembly
XH93_RS15745	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XH93_RS15750	COG1138	Cytochrome C-type biogenesis protein
XH93_RS15755	COG3088	subunit of a heme lyase
XH93_RS15760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XH93_RS15765	COG0745	RESPONSE REGULATOR receiver
XH93_RS15770	COG2205	protein histidine kinase activity
XH93_RS15775	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XH93_RS15805	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XH93_RS15810	COG3383	formate dehydrogenase (NAD+) activity
XH93_RS15825	COG0583	DNA-binding transcription factor activity
XH93_RS15830	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XH93_RS15835	COG2943	transferase activity, transferring hexosyl groups
XH93_RS15840	COG2205	protein histidine kinase activity
XH93_RS15840	COG2202	Pas domain
XH93_RS15855	COG4191	Histidine kinase
XH93_RS15870	COG0667	Aldo Keto reductase
XH93_RS15885	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS15885	COG3321	synthase
XH93_RS15885	COG0604	alcohol dehydrogenase
XH93_RS15935	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH93_RS15945	COG1802	Transcriptional regulator
XH93_RS15970	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XH93_RS15975	COG0028	Belongs to the TPP enzyme family
XH93_RS15975	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
XH93_RS15990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XH93_RS16000	COG0129	dihydroxy-acid dehydratase activity
XH93_RS16015	COG1024	Enoyl-CoA hydratase
XH93_RS16040	COG1846	Transcriptional regulator
XH93_RS16070	COG4191	Histidine kinase
XH93_RS16070	COG0784	Response regulator, receiver
XH93_RS16080	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XH93_RS16100	COG1850	ribulose-bisphosphate carboxylase activity
XH93_RS16105	COG4451	ribulose bisphosphate carboxylase, small
XH93_RS16115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XH93_RS16120	COG4213	ABC transporter substrate-binding protein
XH93_RS16130	COG4214	carbohydrate transport
XH93_RS16135	COG4774	siderophore transport
XH93_RS16140	COG0483	inositol monophosphate 1-phosphatase activity
XH93_RS16150	COG0583	DNA-binding transcription factor activity
XH93_RS16155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH93_RS16170	COG0625	glutathione transferase activity
XH93_RS16175	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH93_RS16180	COG1177	transmembrane transport
XH93_RS16200	COG1228	amidohydrolase
XH93_RS16235	COG0778	Nitroreductase
XH93_RS16245	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XH93_RS16255	COG1492	cobalamin metabolic process
XH93_RS16280	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XH93_RS16300	COG2099	Precorrin-6x reductase
XH93_RS16315	COG2875	Belongs to the precorrin methyltransferase family
XH93_RS16320	COG1797	cobyrinic acid a,c-diamide synthase activity
XH93_RS16325	COG1648	precorrin-2 dehydrogenase activity
XH93_RS16325	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XH93_RS16380	COG0583	DNA-binding transcription factor activity
XH93_RS16405	COG1024	Enoyl-CoA hydratase
XH93_RS16410	COG1960	acyl-CoA dehydrogenase activity
XH93_RS16445	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH93_RS16460	COG1450	Type ii and iii secretion system protein
XH93_RS16465	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XH93_RS16470	COG1459	type II secretion system
XH93_RS16550	COG0647	UMP catabolic process
XH93_RS16555	COG1070	Carbohydrate kinase
XH93_RS16565	COG1653	transport
XH93_RS16570	COG1175	transmembrane transport
XH93_RS16585	COG3842	ATPase activity
XH93_RS16595	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XH93_RS16600	COG0235	Class ii aldolase
XH93_RS16635	COG1137	ATPase activity
XH93_RS16645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XH93_RS16655	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XH93_RS16675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XH93_RS16690	COG1228	amidohydrolase
XH93_RS16695	COG1228	amidohydrolase
XH93_RS16700	COG2986	histidine ammonia-lyase
XH93_RS16705	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XH93_RS16710	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS16740	COG0583	DNA-binding transcription factor activity
XH93_RS16760	COG3485	protocatechuate 3,4-dioxygenase
XH93_RS16765	COG3485	protocatechuate 3,4-dioxygenase
XH93_RS16785	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XH93_RS16800	COG3960	tartronate-semialdehyde synthase activity
XH93_RS16805	COG3622	Belongs to the hyi family
XH93_RS16810	COG2084	Dehydrogenase
XH93_RS16875	COG2233	PERMEase
XH93_RS16890	COG3437	response regulator, receiver
XH93_RS16900	COG2205	protein histidine kinase activity
XH93_RS16900	COG3437	response regulator, receiver
XH93_RS16900	COG4999	Histidine kinase
XH93_RS16900	COG3850	Histidine kinase
XH93_RS16920	COG1414	Transcriptional regulator
XH93_RS16930	COG1137	ATPase activity
XH93_RS16955	COG4310	Domain of unknown function (DUF2172)
XH93_RS16970	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
XH93_RS16985	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XH93_RS17010	COG1216	Glycosyl transferase, family 2
XH93_RS17015	COG2226	methyltransferase
XH93_RS17025	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
XH93_RS17035	COG2197	response regulator
XH93_RS17055	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
XH93_RS17060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XH93_RS17065	COG2197	response regulator
XH93_RS17070	COG2197	response regulator
XH93_RS17075	COG1116	anion transmembrane transporter activity
XH93_RS17080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XH93_RS17085	COG4521	taurine ABC transporter
XH93_RS17090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XH93_RS17105	COG1053	succinate dehydrogenase
XH93_RS17120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XH93_RS17175	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XH93_RS17185	COG0583	DNA-binding transcription factor activity
XH93_RS17190	COG4948	Mandelate Racemase Muconate Lactonizing
XH93_RS17195	COG3485	protocatechuate 3,4-dioxygenase
XH93_RS17205	COG0196	riboflavin kinase activity
XH93_RS17230	COG2202	Pas domain
XH93_RS17230	COG2205	protein histidine kinase activity
XH93_RS17235	COG2084	Dehydrogenase
XH93_RS17245	COG0489	protein tyrosine kinase activity
XH93_RS17255	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
XH93_RS17260	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
XH93_RS17270	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
XH93_RS17275	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XH93_RS17285	COG0546	phosphoglycolate phosphatase activity
XH93_RS17290	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
XH93_RS17330	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XH93_RS17335	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XH93_RS17355	COG0215	cysteine-tRNA ligase activity
XH93_RS17365	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XH93_RS17380	COG5265	(ABC) transporter
XH93_RS17385	COG0688	phosphatidylethanolamine metabolic process
XH93_RS17400	COG0861	Integral membrane protein TerC family
XH93_RS17410	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS17425	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XH93_RS17435	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
XH93_RS17440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XH93_RS17450	COG0318	PFAM AMP-dependent synthetase and ligase
XH93_RS17465	COG2030	dehydratase
XH93_RS17475	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS17480	COG1960	acyl-CoA dehydrogenase activity
XH93_RS17485	COG0840	transmembrane signaling receptor activity
XH93_RS17490	COG0028	Belongs to the TPP enzyme family
XH93_RS17495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XH93_RS17520	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XH93_RS17530	COG3158	transport of potassium into the cell
XH93_RS17535	COG3158	transport of potassium into the cell
XH93_RS17540	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XH93_RS17545	COG0436	Aminotransferase
XH93_RS17550	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
XH93_RS17560	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XH93_RS17565	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XH93_RS17570	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XH93_RS17575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XH93_RS17590	COG1285	pathogenesis
XH93_RS17605	COG5001	Diguanylate cyclase
XH93_RS17625	COG3258	Cytochrome c
XH93_RS17635	COG0531	amino acid
XH93_RS17670	COG0583	DNA-binding transcription factor activity
XH93_RS17685	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XH93_RS17890	COG5410	chromosome segregation
XH93_RS17900	COG1278	Cold shock
XH93_RS18085	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XH93_RS18125	COG1475	DNA binding
XH93_RS18170	COG0456	acetyltransferase
XH93_RS18170	COG1214	PFAM Peptidase M22, glycoprotease
XH93_RS18200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XH93_RS18220	COG4774	siderophore transport
XH93_RS18225	COG3128	pkhd-type hydroxylase
XH93_RS18235	COG0848	biopolymer transport protein
XH93_RS18255	COG1994	Peptidase M50
XH93_RS18265	COG0583	DNA-binding transcription factor activity
XH93_RS18270	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS18275	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS18280	COG0129	dihydroxy-acid dehydratase activity
XH93_RS18285	COG1609	Transcriptional regulator
XH93_RS18290	COG3842	ATPase activity
XH93_RS18305	COG0395	ABC-type sugar transport system, permease component
XH93_RS18310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XH93_RS18315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XH93_RS18320	COG0800	Aldolase
XH93_RS18325	COG0183	Belongs to the thiolase family
XH93_RS18330	COG0318	PFAM AMP-dependent synthetase and ligase
XH93_RS18350	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XH93_RS18370	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
XH93_RS18370	COG2066	Belongs to the glutaminase family
XH93_RS18395	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XH93_RS18405	COG4689	acetoacetate decarboxylase
XH93_RS18420	COG2271	Major facilitator Superfamily
XH93_RS18425	COG0183	Belongs to the thiolase family
XH93_RS18455	COG0559	Belongs to the binding-protein-dependent transport system permease family
XH93_RS18475	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XH93_RS18480	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XH93_RS18485	COG0549	Belongs to the carbamate kinase family
XH93_RS18515	COG4191	Histidine kinase
XH93_RS18520	COG1024	Enoyl-CoA hydratase
XH93_RS18545	COG1960	acyl-CoA dehydrogenase activity
XH93_RS18560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XH93_RS18570	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS18575	COG0493	'glutamate synthase
XH93_RS18575	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
XH93_RS18580	COG2814	Major facilitator Superfamily
XH93_RS18585	COG0583	DNA-binding transcription factor activity
XH93_RS18595	COG0488	(ABC) transporter
XH93_RS18600	COG1671	Belongs to the UPF0178 family
XH93_RS18620	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XH93_RS18655	COG2130	NADP-dependent
XH93_RS18680	COG2814	Major facilitator Superfamily
XH93_RS18700	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XH93_RS18700	COG0519	Catalyzes the synthesis of GMP from XMP
XH93_RS18715	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS18720	COG0583	DNA-binding transcription factor activity
XH93_RS18730	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
XH93_RS18745	COG2226	methyltransferase
XH93_RS18775	COG0242	peptide deformylase activity
XH93_RS18785	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XH93_RS18800	COG0456	acetyltransferase
XH93_RS18800	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
XH93_RS18820	COG0583	DNA-binding transcription factor activity
XH93_RS18835	COG0477	Major facilitator Superfamily
XH93_RS18845	COG0583	DNA-binding transcription factor activity
XH93_RS18850	COG0477	Major facilitator Superfamily
XH93_RS18860	COG1764	response to oxidative stress
XH93_RS18865	COG1846	Transcriptional regulator
XH93_RS18880	COG1690	Belongs to the RtcB family
XH93_RS18905	COG2814	Major facilitator Superfamily
XH93_RS18960	COG0583	DNA-binding transcription factor activity
XH93_RS18975	COG3385	transposase activity
XH93_RS18985	COG0625	glutathione transferase activity
XH93_RS18990	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XH93_RS19000	COG1301	dicarboxylic acid transport
XH93_RS19020	COG1393	Belongs to the ArsC family
XH93_RS19060	COG4214	carbohydrate transport
XH93_RS19065	COG1392	Phosphate transport regulator
XH93_RS19070	COG0306	phosphate transporter
XH93_RS19095	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XH93_RS19100	COG0318	PFAM AMP-dependent synthetase and ligase
XH93_RS19115	COG1160	GTP binding
XH93_RS19140	COG5433	transposase activity
XH93_RS19145	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS19155	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
XH93_RS19160	COG1286	toxin biosynthetic process
XH93_RS19195	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XH93_RS19200	COG0305	Participates in initiation and elongation during chromosome replication
XH93_RS19210	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XH93_RS19230	COG0359	binds to the 23S rRNA
XH93_RS19240	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
XH93_RS19245	COG0360	Binds together with S18 to 16S ribosomal RNA
XH93_RS19260	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XH93_RS19275	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XH93_RS19280	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XH93_RS19285	COG1561	YicC-like family, N-terminal region
XH93_RS19290	COG0194	GDP metabolic process
XH93_RS19315	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XH93_RS19330	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XH93_RS19340	COG0795	lipopolysaccharide-transporting ATPase activity
XH93_RS19345	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XH93_RS19360	COG0488	(ABC) transporter
XH93_RS19375	COG0105	UTP biosynthetic process
XH93_RS19380	COG0861	Integral membrane protein TerC family
XH93_RS19390	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XH93_RS19400	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XH93_RS19405	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XH93_RS19410	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XH93_RS19415	COG1278	Cold shock
XH93_RS19420	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
XH93_RS19430	COG3685	Protein conserved in bacteria
XH93_RS19440	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
XH93_RS19445	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XH93_RS19455	COG0281	malic enzyme
XH93_RS19455	COG0280	phosphate acetyltransferase
XH93_RS19480	COG0386	Belongs to the glutathione peroxidase family
XH93_RS19490	COG3045	CreA protein
XH93_RS19525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XH93_RS19535	COG3483	tryptophan 2,3-dioxygenase activity
XH93_RS19545	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
XH93_RS19585	COG0583	DNA-binding transcription factor activity
XH93_RS19600	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XH93_RS19610	COG0028	Belongs to the TPP enzyme family
XH93_RS19620	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS19635	COG2365	Tyrosine phosphatase family
XH93_RS19650	COG0174	glutamine synthetase
XH93_RS19690	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XH93_RS19690	COG2010	Cytochrome c
XH93_RS19710	COG0488	(ABC) transporter
XH93_RS19715	COG1943	Transposase
XH93_RS19740	COG0778	Nitroreductase
XH93_RS19765	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS19775	COG1376	ErfK ybiS ycfS ynhG family protein
XH93_RS19785	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XH93_RS19800	COG2226	methyltransferase
XH93_RS19835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XH93_RS19845	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XH93_RS19855	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XH93_RS19900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XH93_RS19925	COG3750	Belongs to the UPF0335 family
XH93_RS19935	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XH93_RS19940	COG0697	spore germination
XH93_RS19945	COG4191	Histidine kinase
XH93_RS19945	COG0784	Response regulator, receiver
XH93_RS19980	COG3263	regulation of cellular component size
XH93_RS19985	COG0657	acetylesterase activity
XH93_RS20000	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
XH93_RS20005	COG0471	metal ion transport
XH93_RS20015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XH93_RS20045	COG4565	transcriptional regulatory protein
XH93_RS20050	COG0784	Response regulator, receiver
XH93_RS20055	COG5002	protein histidine kinase activity
XH93_RS20065	COG0511	ligase activity, forming carbon-carbon bonds
XH93_RS20070	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XH93_RS20095	COG0436	Aminotransferase
XH93_RS20100	COG1268	BioY protein
XH93_RS20105	COG1301	dicarboxylic acid transport
XH93_RS20110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XH93_RS20115	COG1530	ribonuclease E activity
XH93_RS20115	COG1530	ribonuclease E activity
XH93_RS20120	COG0860	N-Acetylmuramoyl-L-alanine amidase
XH93_RS20125	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XH93_RS20135	COG2084	Dehydrogenase
XH93_RS20145	COG2192	nodulation
XH93_RS20160	COG0438	transferase activity, transferring glycosyl groups
XH93_RS20170	COG0438	transferase activity, transferring glycosyl groups
XH93_RS20195	COG0739	heme binding
XH93_RS20200	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XH93_RS20210	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS20215	COG1733	regulation of RNA biosynthetic process
XH93_RS20220	COG2226	methyltransferase
XH93_RS20230	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XH93_RS20235	COG2271	Major facilitator Superfamily
XH93_RS20240	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XH93_RS20245	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
XH93_RS20260	COG2945	thiolester hydrolase activity
XH93_RS20265	COG1104	cysteine desulfurase activity
XH93_RS20270	COG0719	Fe-S assembly protein
XH93_RS20275	COG0396	ATPase activity
XH93_RS20280	COG0719	Fe-S assembly protein
XH93_RS20285	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XH93_RS20295	COG0316	Belongs to the HesB IscA family
XH93_RS20310	COG0513	Belongs to the DEAD box helicase family
XH93_RS20330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XH93_RS20340	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS20350	COG0187	DNA topoisomerase II activity
XH93_RS20360	COG0586	Pfam SNARE associated Golgi protein
XH93_RS20370	COG1234	tRNA 3'-trailer cleavage
XH93_RS20395	COG3243	poly(R)-hydroxyalkanoic acid synthase
XH93_RS20405	COG0436	Aminotransferase
XH93_RS20415	COG1494	fructose-1,6-bisphosphatase
XH93_RS20425	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XH93_RS20450	COG1917	Cupin 2, conserved barrel domain protein
XH93_RS20450	COG4977	sequence-specific DNA binding
XH93_RS20470	COG2195	Cleaves the N-terminal amino acid of tripeptides
XH93_RS20475	COG0776	regulation of translation
XH93_RS20515	COG2814	Major facilitator Superfamily
XH93_RS20535	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XH93_RS20545	COG0649	NAD binding
XH93_RS20550	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XH93_RS20560	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XH93_RS20575	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XH93_RS20580	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XH93_RS20590	COG0713	ATP synthesis coupled electron transport
XH93_RS20605	COG1007	ATP synthesis coupled electron transport
XH93_RS20620	COG0346	lactoylglutathione lyase activity
XH93_RS20640	COG1172	Belongs to the binding-protein-dependent transport system permease family
XH93_RS20645	COG1129	ABC transporter
XH93_RS20665	COG4774	siderophore transport
XH93_RS20690	COG1276	copper resistance
XH93_RS20695	COG0442	prolyl-tRNA aminoacylation
XH93_RS20705	COG1136	(ABC) transporter
XH93_RS20730	COG0052	Belongs to the universal ribosomal protein uS2 family
XH93_RS20735	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XH93_RS20740	COG0528	UMP kinase activity
XH93_RS20745	COG0233	cytoplasmic translational termination
XH93_RS20750	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XH93_RS20760	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XH93_RS20765	COG0750	zinc metalloprotease
XH93_RS20770	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XH93_RS20775	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XH93_RS20780	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XH93_RS20790	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XH93_RS20800	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XH93_RS20810	COG0640	Transcriptional regulator
XH93_RS20815	COG0372	Belongs to the citrate synthase family
XH93_RS20820	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XH93_RS20825	COG2249	NAD(P)H dehydrogenase (quinone) activity
XH93_RS20830	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XH93_RS20855	COG0477	Major facilitator Superfamily
XH93_RS20875	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XH93_RS20880	COG0303	'Molybdopterin
XH93_RS20885	COG1011	Hydrolase
XH93_RS20905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XH93_RS20915	COG1278	Cold shock
XH93_RS20930	COG1902	pentaerythritol trinitrate reductase activity
XH93_RS20935	COG0793	Belongs to the peptidase S41A family
XH93_RS20940	COG5001	Diguanylate cyclase
XH93_RS20945	COG0315	cyclic pyranopterin monophosphate synthase activity
XH93_RS20950	COG0134	indole-3-glycerol-phosphate synthase activity
XH93_RS20955	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XH93_RS20965	COG0149	triose-phosphate isomerase activity
XH93_RS20985	COG0504	CTP synthase activity
XH93_RS20995	COG2205	protein histidine kinase activity
XH93_RS21000	COG0745	RESPONSE REGULATOR receiver
XH93_RS21015	COG2877	3-deoxy-8-phosphooctulonate synthase activity
XH93_RS21020	COG2814	Major facilitator Superfamily
XH93_RS21030	COG0346	lactoylglutathione lyase activity
XH93_RS21040	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XH93_RS21045	COG0148	phosphopyruvate hydratase activity
XH93_RS21050	COG1063	alcohol dehydrogenase
XH93_RS21055	COG1181	Belongs to the D-alanine--D-alanine ligase family
XH93_RS21060	COG0431	NADPH-dependent FMN reductase
XH93_RS21070	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XH93_RS21075	COG0508	dehydrogenase complex catalyzes the overall conversion of
XH93_RS21075	COG0022	dehydrogenase e1 component
XH93_RS21085	COG0508	dehydrogenase complex catalyzes the overall conversion of
XH93_RS21100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XH93_RS21105	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
XH93_RS21115	COG3385	transposase activity
XH93_RS21150	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XH93_RS21195	COG3734	2-keto-3-deoxy-galactonokinase
XH93_RS21200	COG0800	Aldolase
XH93_RS21265	COG0071	Belongs to the small heat shock protein (HSP20) family
XH93_RS21360	COG2204	response regulator
XH93_RS21425	COG2373	Large extracellular alpha-helical protein
XH93_RS21430	COG4953	penicillin-binding protein 1C
XH93_RS21435	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
XH93_RS21505	COG4964	Belongs to the GSP D family
XH93_RS21515	COG0626	cystathionine gamma-synthase activity
XH93_RS21520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XH93_RS21525	COG4597	amino acid ABC transporter
XH93_RS21530	COG0765	amino acid transport
XH93_RS21535	COG1126	abc transporter atp-binding protein
XH93_RS21540	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
XH93_RS21550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XH93_RS21610	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XH93_RS21625	COG0525	valine-tRNA ligase activity
XH93_RS21640	COG2094	Belongs to the DNA glycosylase MPG family
XH93_RS21645	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XH93_RS21650	COG2867	negative regulation of translational initiation
XH93_RS21670	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XH93_RS21670	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
XH93_RS21695	COG5000	phosphorelay sensor kinase activity
XH93_RS21700	COG2204	response regulator
XH93_RS21705	COG1923	regulation of RNA biosynthetic process
XH93_RS21710	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XH93_RS21715	COG2239	Acts as a magnesium transporter
XH93_RS21720	COG3956	TIGRFAM MazG family protein
XH93_RS21725	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
XH93_RS21745	COG1024	Enoyl-CoA hydratase
XH93_RS21755	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XH93_RS21765	COG0318	PFAM AMP-dependent synthetase and ligase
XH93_RS21775	COG1846	Transcriptional regulator
XH93_RS21780	COG0778	Nitroreductase
XH93_RS21785	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
XH93_RS21785	COG0321	lipoyl(octanoyl) transferase activity
XH93_RS21790	COG0084	hydrolase, TatD family'
XH93_RS21805	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XH93_RS21810	COG1686	Belongs to the peptidase S11 family
XH93_RS21885	COG2814	Major facilitator Superfamily
XH93_RS21905	COG0784	Response regulator, receiver
XH93_RS21905	COG4191	Histidine kinase
XH93_RS21910	COG1959	2 iron, 2 sulfur cluster binding
XH93_RS21910	COG1295	ribonuclease BN
XH93_RS21915	COG5001	Diguanylate cyclase
XH93_RS21915	COG2203	Gaf domain
XH93_RS21915	COG3706	GGDEF domain
XH93_RS21915	COG4251	negative regulation of phosphorylation
XH93_RS21945	COG0210	DNA helicase
XH93_RS21960	COG0477	Major facilitator Superfamily
XH93_RS21965	COG1960	acyl-CoA dehydrogenase activity
XH93_RS21985	COG1175	transmembrane transport
XH93_RS21990	COG0395	ABC-type sugar transport system, permease component
XH93_RS22005	COG0154	amidase activity
XH93_RS22040	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XH93_RS22040	COG0473	3-isopropylmalate dehydrogenase activity
XH93_RS22045	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
XH93_RS22050	COG1984	allophanate hydrolase subunit 2
XH93_RS22055	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
XH93_RS22070	COG1116	anion transmembrane transporter activity
XH93_RS22070	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XH93_RS22075	COG3707	response regulator
XH93_RS22080	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XH93_RS22095	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XH93_RS22105	COG1253	flavin adenine dinucleotide binding
XH93_RS22110	COG1183	phosphatidylcholine synthase activity
XH93_RS22115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XH93_RS22120	COG0679	Auxin Efflux Carrier
XH93_RS22130	COG2814	Major facilitator Superfamily
XH93_RS22155	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XH93_RS22180	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XH93_RS22225	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XH93_RS22300	COG1250	3-hydroxyacyl-CoA dehydrogenase
XH93_RS22325	COG1253	flavin adenine dinucleotide binding
XH93_RS22330	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XH93_RS22345	COG0251	oxidation-reduction process
XH93_RS22350	COG0697	spore germination
XH93_RS22370	COG0343	queuine tRNA-ribosyltransferase activity
XH93_RS22375	COG1309	transcriptional regulator
XH93_RS22385	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XH93_RS22395	COG1172	Belongs to the binding-protein-dependent transport system permease family
XH93_RS22400	COG1129	ABC transporter
XH93_RS22410	COG1172	Belongs to the binding-protein-dependent transport system permease family
XH93_RS22415	COG1129	ABC transporter
XH93_RS22435	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XH93_RS22455	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XH93_RS22465	COG3158	transport of potassium into the cell
XH93_RS22470	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
XH93_RS22480	COG0629	single-stranded DNA binding
XH93_RS22495	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XH93_RS22525	COG1120	ATPase activity
XH93_RS22595	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
XH93_RS22625	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XH93_RS22630	COG1862	Preprotein translocase
XH93_RS22645	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XH93_RS22655	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XH93_RS22665	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XH93_RS22670	COG0805	protein transport
XH93_RS22675	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XH93_RS22680	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XH93_RS22685	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XH93_RS22690	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XH93_RS22695	COG1472	Belongs to the glycosyl hydrolase 3 family
XH93_RS22705	COG0018	arginyl-trna synthetase
XH93_RS22710	COG0232	Belongs to the dGTPase family. Type 2 subfamily
XH93_RS22715	COG0316	Belongs to the HesB IscA family
XH93_RS22725	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XH93_RS22730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XH93_RS22745	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
XH93_RS22750	COG0129	dihydroxy-acid dehydratase activity
XH93_RS22765	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XH93_RS22770	COG1960	acyl-CoA dehydrogenase activity
XH93_RS22780	COG1522	sequence-specific DNA binding
XH93_RS22795	COG2192	nodulation
XH93_RS22805	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
XH93_RS22830	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XH93_RS22940	COG1278	Cold shock
XH93_RS22945	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XH93_RS22995	COG0625	glutathione transferase activity
XH93_RS23040	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XH93_RS23070	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XH93_RS23085	COG3152	Membrane
XH93_RS23095	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XH93_RS23110	COG2226	methyltransferase
XH93_RS23145	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
XH93_RS23150	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XH93_RS23155	COG0740	serine-type endopeptidase activity
XH93_RS23160	COG0544	peptidyl-prolyl cis-trans isomerase activity
XH93_RS23185	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XH93_RS23185	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XH93_RS23190	COG0347	Belongs to the P(II) protein family
XH93_RS23195	COG0174	glutamine synthetase
XH93_RS23220	COG4191	Histidine kinase
XH93_RS23220	COG0784	Response regulator, receiver
XH93_RS23225	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XH93_RS23250	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XH93_RS23255	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
XH93_RS23270	COG1024	Enoyl-CoA hydratase
XH93_RS23295	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
XH93_RS23300	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
XH93_RS23310	COG1612	heme a metabolic process
XH93_RS23350	COG1596	polysaccharide export
XH93_RS23355	COG0438	transferase activity, transferring glycosyl groups
XH93_RS23370	COG1846	Transcriptional regulator
XH93_RS23375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XH93_RS23380	COG3268	Saccharopine dehydrogenase
XH93_RS23400	COG0318	PFAM AMP-dependent synthetase and ligase
XH93_RS23460	COG0776	regulation of translation
XH93_RS23465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XH93_RS23470	COG0416	fatty acid biosynthetic process
XH93_RS23490	COG2824	Alkylphosphonate utilization operon protein PhnA
XH93_RS23540	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XH93_RS23545	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XH93_RS23550	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XH93_RS23555	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XH93_RS23565	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XH93_RS23565	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XH93_RS23570	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XH93_RS23575	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XH93_RS23590	COG4774	siderophore transport
XH93_RS23600	COG2311	Membrane
XH93_RS23675	COG1595	DNA-templated transcription, initiation
XH93_RS23720	COG0113	porphobilinogen synthase activity
XH93_RS23730	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
XH93_RS23735	COG1914	H( )-stimulated, divalent metal cation uptake system
XH93_RS23750	COG2268	Band 7 protein
XH93_RS23775	COG1230	cation diffusion facilitator family transporter
XH93_RS23780	COG1230	cation diffusion facilitator family transporter
XH93_RS23785	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
XH93_RS23790	COG1381	Involved in DNA repair and RecF pathway recombination
XH93_RS23800	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XH93_RS23805	COG0571	ribonuclease III activity
XH93_RS23810	COG0681	Belongs to the peptidase S26 family
XH93_RS23815	COG0736	holo-[acyl-carrier-protein] synthase activity
XH93_RS23820	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XH93_RS23830	COG1758	RNA polymerase activity
XH93_RS23840	COG1573	uracil-dna glycosylase
XH93_RS23850	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XH93_RS23855	COG1970	mechanosensitive ion channel activity
XH93_RS23860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XH93_RS23865	COG0741	lytic transglycosylase activity
XH93_RS23895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XH93_RS23925	COG4964	Belongs to the GSP D family
XH93_RS23960	COG0489	protein tyrosine kinase activity
XH93_RS24020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XH93_RS24075	COG2223	nitrite transmembrane transporter activity
XH93_RS24090	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
XH93_RS24105	COG0154	amidase activity
XH93_RS24115	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
XH93_RS24130	COG0583	DNA-binding transcription factor activity
XH93_RS24140	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XH93_RS24150	COG0583	DNA-binding transcription factor activity
XH93_RS24170	COG1960	acyl-CoA dehydrogenase activity
XH93_RS24185	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XH93_RS24190	COG0540	Belongs to the ATCase OTCase family
XH93_RS24195	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XH93_RS24200	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
XH93_RS24205	COG0154	amidase activity
XH93_RS24210	COG0758	DNA mediated transformation
XH93_RS24215	COG1733	regulation of RNA biosynthetic process
XH93_RS24220	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XH93_RS24230	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS24245	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XH93_RS24250	COG0557	exoribonuclease II activity
XH93_RS24265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XH93_RS24270	COG0267	Belongs to the bacterial ribosomal protein bL33 family
XH93_RS24285	COG0004	ammonium transporteR
XH93_RS24300	COG1309	transcriptional regulator
XH93_RS24315	COG0784	Response regulator, receiver
XH93_RS24325	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XH93_RS24355	COG0537	adenosine 5'-monophosphoramidase activity
XH93_RS24360	COG1720	tRNA m6t6A37 methyltransferase activity
XH93_RS24395	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XH93_RS24410	COG2814	Major facilitator Superfamily
XH93_RS24420	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
XH93_RS24435	COG1686	Belongs to the peptidase S11 family
XH93_RS24470	COG1192	Involved in chromosome partitioning
XH93_RS24480	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XH93_RS24510	COG0625	glutathione transferase activity
XH93_RS24525	COG0656	L-ascorbic acid biosynthetic process
XH93_RS24555	COG1802	Transcriptional regulator
XH93_RS24565	COG2271	Major facilitator Superfamily
XH93_RS24600	COG0411	ABC transporter
XH93_RS24605	COG1131	(ABC) transporter
XH93_RS24630	COG2239	Acts as a magnesium transporter
XH93_RS24635	COG0726	polysaccharide deacetylase
XH93_RS24640	COG0726	polysaccharide deacetylase
XH93_RS24650	COG3831	ATPase activity
XH93_RS24655	COG0714	Associated with various cellular activities
XH93_RS24665	COG3552	Protein containing von Willebrand factor type A (VWA) domain
XH93_RS24685	COG0321	lipoyl(octanoyl) transferase activity
XH93_RS24710	COG1090	epimerase
XH93_RS24730	COG1254	Belongs to the acylphosphatase family
XH93_RS24735	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
XH93_RS24740	COG4770	biotin carboxylase activity
XH93_RS24760	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XH93_RS24770	COG5001	Diguanylate cyclase
XH93_RS24810	COG0450	alkyl hydroperoxide reductase
XH93_RS24815	COG0697	spore germination
XH93_RS24845	COG0475	glutathione-regulated potassium exporter activity
XH93_RS24885	COG1309	transcriptional regulator
XH93_RS24960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XH93_RS24965	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS24970	COG2030	dehydratase
XH93_RS24995	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XH93_RS24995	COG2010	Cytochrome c
XH93_RS25000	COG2860	membrane
XH93_RS25065	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XH93_RS25090	COG0697	spore germination
XH93_RS25095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XH93_RS25105	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XH93_RS25150	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XH93_RS25155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XH93_RS25160	COG3746	phosphate-selective porin O and P
XH93_RS25165	COG1733	regulation of RNA biosynthetic process
XH93_RS25180	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS25185	COG0203	ribosomal protein L17
XH93_RS25190	COG0202	RNA polymerase activity
XH93_RS25195	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
XH93_RS25200	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
XH93_RS25205	COG0563	adenylate kinase activity
XH93_RS25210	COG0201	protein transport
XH93_RS25215	COG0201	protein transport
XH93_RS25220	COG0200	Binds to the 23S rRNA
XH93_RS25225	COG1841	ribosomal large subunit assembly
XH93_RS25230	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
XH93_RS25235	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
XH93_RS25240	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
XH93_RS25245	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
XH93_RS25250	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
XH93_RS25255	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XH93_RS25260	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XH93_RS25265	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
XH93_RS25270	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XH93_RS25275	COG0255	Belongs to the universal ribosomal protein uL29 family
XH93_RS25280	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XH93_RS25285	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
XH93_RS25290	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
XH93_RS25295	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
XH93_RS25300	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XH93_RS25305	COG0089	rRNA binding
XH93_RS25310	COG0088	Forms part of the polypeptide exit tunnel
XH93_RS25315	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
XH93_RS25320	COG0051	transcription antitermination factor activity, RNA binding
XH93_RS25325	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XH93_RS25330	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XH93_RS25335	COG0049	tRNA binding
XH93_RS25340	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XH93_RS25345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XH93_RS25350	COG1132	(ABC) transporter
XH93_RS25360	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XH93_RS25365	COG0085	RNA polymerase activity
XH93_RS25370	COG0222	ribosome binding
XH93_RS25375	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XH93_RS25380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XH93_RS25385	COG0081	regulation of translation
XH93_RS25390	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XH93_RS25395	COG0250	Participates in transcription elongation, termination and antitermination
XH93_RS25420	COG0318	PFAM AMP-dependent synthetase and ligase
XH93_RS25425	COG2186	Transcriptional regulator
XH93_RS25460	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS25480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XH93_RS25510	COG1960	acyl-CoA dehydrogenase activity
XH93_RS25520	COG0251	oxidation-reduction process
XH93_RS25525	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH93_RS25530	COG0243	molybdopterin cofactor binding
XH93_RS25535	COG2146	nitrite reductase [NAD(P)H] activity
XH93_RS25540	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XH93_RS25550	COG2223	nitrite transmembrane transporter activity
XH93_RS25555	COG2815	serine threonine protein kinase
XH93_RS25555	COG0515	serine threonine protein kinase
XH93_RS25585	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
XH93_RS25625	COG0277	FAD linked oxidase domain protein
XH93_RS25640	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XH93_RS25645	COG0459	protein refolding
XH93_RS25655	COG2948	multi-organism process
XH93_RS25680	COG3451	type IV secretory pathway VirB4
XH93_RS25695	COG4962	Type ii secretion system protein e
XH93_RS25720	COG5489	Protein of unknown function (DUF736)
XH93_RS25755	COG1525	nuclease
XH93_RS25775	COG3916	Acyl-homoserine-lactone synthase
XH93_RS25780	COG2771	luxR family
XH93_RS25790	COG2942	2-epimerase
XH93_RS25795	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS25805	COG2211	Major facilitator Superfamily
XH93_RS25830	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS25835	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH93_RS25840	COG0410	ABC transporter
XH93_RS25855	COG0559	Belongs to the binding-protein-dependent transport system permease family
XH93_RS25860	COG0683	leucine binding
XH93_RS25880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XH93_RS25910	COG2423	ornithine cyclodeaminase activity
XH93_RS25930	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XH93_RS25930	COG2755	lipolytic protein G-D-S-L family
XH93_RS25950	COG2176	DNA-directed DNA polymerase activity
XH93_RS25975	COG0318	PFAM AMP-dependent synthetase and ligase
XH93_RS25990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XH93_RS26005	COG1024	Enoyl-CoA hydratase
XH93_RS26030	COG0006	proline dipeptidase activity
XH93_RS26045	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XH93_RS26050	COG0583	DNA-binding transcription factor activity
XH93_RS26055	COG0438	transferase activity, transferring glycosyl groups
XH93_RS26060	COG0071	Belongs to the small heat shock protein (HSP20) family
XH93_RS26065	COG0071	Belongs to the small heat shock protein (HSP20) family
XH93_RS26075	COG4191	Histidine kinase
XH93_RS26075	COG0784	Response regulator, receiver
XH93_RS26080	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XH93_RS26085	COG2095	MarC family integral membrane protein
XH93_RS26095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XH93_RS26105	COG0071	Belongs to the small heat shock protein (HSP20) family
XH93_RS26115	COG0459	protein refolding
XH93_RS26120	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XH93_RS26130	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XH93_RS26135	COG2249	NAD(P)H dehydrogenase (quinone) activity
XH93_RS26140	COG0583	DNA-binding transcription factor activity
XH93_RS26145	COG0071	Belongs to the small heat shock protein (HSP20) family
XH93_RS26170	COG4208	sulfate ABC transporter
XH93_RS26175	COG1176	ABC-type spermidine putrescine transport system, permease component I
XH93_RS26185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XH93_RS26195	COG3842	ATPase activity
XH93_RS26200	COG0583	DNA-binding transcription factor activity
XH93_RS26220	COG0747	negative chemotaxis
XH93_RS26230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH93_RS26255	COG0583	DNA-binding transcription factor activity
XH93_RS26265	COG1012	belongs to the aldehyde dehydrogenase family
XH93_RS26270	COG2084	Dehydrogenase
XH93_RS26320	COG3795	YCII-related domain
XH93_RS26380	COG0583	DNA-binding transcription factor activity
XH93_RS26385	COG3665	Urea carboxylase-associated protein
XH93_RS26425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XH93_RS26440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XH93_RS26540	COG1902	pentaerythritol trinitrate reductase activity
XH93_RS26550	COG2130	NADP-dependent
XH93_RS26615	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XH93_RS26625	COG0583	DNA-binding transcription factor activity
XH93_RS26645	COG0179	Fumarylacetoacetate (FAA) hydrolase
XH93_RS26660	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XH93_RS26685	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XH93_RS26690	COG0302	gtp cyclohydrolase
XH93_RS26720	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
XH93_RS26735	COG0531	amino acid
XH93_RS26745	COG2814	Major facilitator Superfamily
XH93_RS26755	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XH93_RS26770	COG5001	Diguanylate cyclase
XH93_RS26780	COG1752	Esterase of the alpha-beta hydrolase superfamily
XH93_RS26785	COG0517	IMP dehydrogenase activity
XH93_RS26805	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XH93_RS26825	COG1982	Orn Lys Arg decarboxylase major
XH93_RS26835	COG3360	Dodecin
XH93_RS26855	COG2423	ornithine cyclodeaminase activity
XH93_RS26875	COG0596	Alpha beta hydrolase
XH93_RS26900	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XH93_RS26905	COG0747	negative chemotaxis
XH93_RS26920	COG0683	leucine binding
XH93_RS26925	COG3964	amidohydrolase
XH93_RS26935	COG1063	alcohol dehydrogenase
XH93_RS26950	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XH93_RS26960	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XH93_RS26970	COG0412	Dienelactone hydrolase
XH93_RS27035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XH93_RS27055	COG0747	negative chemotaxis
XH93_RS27070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XH93_RS27075	COG0601	transmembrane transport
XH93_RS27080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH93_RS27085	COG4172	Belongs to the ABC transporter superfamily
XH93_RS27095	COG1473	amidohydrolase
XH93_RS27100	COG0154	amidase activity
XH93_RS27105	COG1024	Enoyl-CoA hydratase
XH93_RS27115	COG3321	synthase
XH93_RS27115	COG0604	alcohol dehydrogenase
XH93_RS27125	COG0625	glutathione transferase activity
XH93_RS27130	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
XH93_RS27140	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
XH93_RS27145	COG1546	Belongs to the CinA family
XH93_RS27145	COG1058	Belongs to the CinA family
XH93_RS27150	COG2308	Evidence 4 Homologs of previously reported genes of
XH93_RS27195	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XH93_RS27225	COG4221	oxidoreductase activity
XH93_RS27235	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XH93_RS27245	COG5425	PFAM Usg family protein
XH93_RS27250	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XH93_RS27255	COG0459	protein refolding
XH93_RS27295	COG1672	PFAM Archaeal ATPase
XH93_RS27295	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XH93_RS27315	COG1335	isochorismatase
XH93_RS27325	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
XH93_RS27370	COG1024	Enoyl-CoA hydratase
XH93_RS27370	COG1250	3-hydroxyacyl-CoA dehydrogenase
XH93_RS27375	COG0384	phenazine biosynthesis protein PhzF
XH93_RS27385	COG0842	Transport permease protein
XH93_RS27390	COG1131	(ABC) transporter
XH93_RS27450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XH93_RS27470	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XH93_RS27475	COG3608	succinylglutamate desuccinylase aspartoacylase
XH93_RS27475	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XH93_RS27510	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
XH93_RS27515	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XH93_RS27520	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XH93_RS27560	COG3191	aminopeptidase activity
XH93_RS27580	COG0515	serine threonine protein kinase
XH93_RS27580	COG2815	serine threonine protein kinase
XH93_RS27590	COG1309	transcriptional regulator
XH93_RS27610	COG3851	Histidine kinase
XH93_RS27620	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
XH93_RS27625	COG1473	amidohydrolase
XH93_RS27645	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
XH93_RS27645	COG2169	Transcriptional regulator
XH93_RS27660	COG2132	Multicopper oxidase
XH93_RS27675	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
XH93_RS27705	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XH93_RS27715	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XH93_RS27720	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
XH93_RS27740	COG0596	Alpha beta hydrolase
XH93_RS27760	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XH93_RS27770	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XH93_RS27795	COG1733	regulation of RNA biosynthetic process
XH93_RS27815	COG3181	Tripartite tricarboxylate transporter family receptor
XH93_RS27820	COG0047	phosphoribosylformylglycinamidine synthase activity
XH93_RS27825	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XH93_RS27830	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XH93_RS27840	COG0583	DNA-binding transcription factor activity
XH93_RS27860	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
XH93_RS27865	COG1116	anion transmembrane transporter activity
XH93_RS27865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XH93_RS27870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XH93_RS27875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XH93_RS27895	COG1309	transcriptional regulator
XH93_RS27905	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
XH93_RS27915	COG0538	isocitrate dehydrogenase activity
XH93_RS27925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XH93_RS27930	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XH93_RS27935	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XH93_RS27940	COG0509	glycine decarboxylation via glycine cleavage system
XH93_RS27945	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XH93_RS27945	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XH93_RS27970	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XH93_RS28015	COG0640	Transcriptional regulator
XH93_RS28020	COG4993	Dehydrogenase
XH93_RS28090	COG1959	2 iron, 2 sulfur cluster binding
XH93_RS28120	COG2917	probably involved in intracellular septation
XH93_RS28145	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
XH93_RS28145	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
XH93_RS28160	COG3832	glyoxalase III activity
XH93_RS28165	COG0640	Transcriptional regulator
XH93_RS28205	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XH93_RS28210	COG1684	flagellar biosynthetic protein fliR
XH93_RS28215	COG1987	bacterial-type flagellum assembly
XH93_RS28220	COG1677	Flagellar hook-basal body complex protein FliE
XH93_RS28225	COG1558	bacterial-type flagellum-dependent cell motility
XH93_RS28240	COG1338	Plays a role in the flagellum-specific transport system
XH93_RS28270	COG1942	4-Oxalocrotonate Tautomerase
XH93_RS28275	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS28280	COG0583	DNA-binding transcription factor activity
XH93_RS28330	COG4786	Flagellar basal body rod
XH93_RS28335	COG4786	Flagellar basal body rod
XH93_RS28345	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
XH93_RS28370	COG1017	nitric oxide dioxygenase activity
XH93_RS28370	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XH93_RS28405	COG3971	2-oxopent-4-enoate hydratase activity
XH93_RS28410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XH93_RS28430	COG1733	regulation of RNA biosynthetic process
XH93_RS28440	COG1706	bacterial-type flagellum-dependent cell motility
XH93_RS28475	COG5443	negative regulation of bacterial-type flagellum assembly
XH93_RS28490	COG1749	Flagellar hook protein flgE
XH93_RS28495	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XH93_RS28520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XH93_RS28545	COG3300	MHYT domain
XH93_RS28545	COG5001	Diguanylate cyclase
XH93_RS28560	COG0392	lysyltransferase activity
XH93_RS28570	COG0747	negative chemotaxis
XH93_RS28575	COG0601	transmembrane transport
XH93_RS28580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH93_RS28585	COG0444	Belongs to the ABC transporter superfamily
XH93_RS28590	COG4608	Belongs to the ABC transporter superfamily
XH93_RS28600	COG0745	RESPONSE REGULATOR receiver
XH93_RS28620	COG0492	ferredoxin-NADP+ reductase activity
XH93_RS28630	COG0633	Ferredoxin
XH93_RS28645	COG3218	ABC-type transport auxiliary lipoprotein component
XH93_RS28645	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XH93_RS28655	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XH93_RS28660	COG4948	Mandelate Racemase Muconate Lactonizing
XH93_RS28665	COG2814	Major facilitator Superfamily
XH93_RS28680	COG0438	transferase activity, transferring glycosyl groups
XH93_RS28690	COG0351	phosphomethylpyrimidine kinase
XH93_RS28700	COG2010	Cytochrome c
XH93_RS28710	COG3909	cytochrome
XH93_RS28720	COG5001	Diguanylate cyclase
XH93_RS28720	COG3300	MHYT domain
XH93_RS28725	COG0728	peptidoglycan biosynthetic process
XH93_RS28735	COG0673	inositol 2-dehydrogenase activity
XH93_RS28740	COG0662	Cupin 2, conserved barrel domain protein
XH93_RS28740	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XH93_RS28755	COG0702	epimerase
XH93_RS28775	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
XH93_RS28775	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
XH93_RS28785	COG0859	PFAM glycosyl transferase family 9
XH93_RS28800	COG1132	(ABC) transporter
XH93_RS28820	COG0281	malic enzyme
XH93_RS28840	COG1053	succinate dehydrogenase
XH93_RS28845	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS28850	COG1414	Transcriptional regulator
XH93_RS28860	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
XH93_RS28865	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XH93_RS28890	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
XH93_RS28935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XH93_RS28955	COG0318	PFAM AMP-dependent synthetase and ligase
XH93_RS28965	COG0559	Belongs to the binding-protein-dependent transport system permease family
XH93_RS28985	COG2942	2-epimerase
XH93_RS28990	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
XH93_RS29010	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XH93_RS29020	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XH93_RS29050	COG0107	imidazoleglycerol-phosphate synthase activity
XH93_RS29055	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XH93_RS29065	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS29070	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XH93_RS29080	COG2089	acid synthase
XH93_RS29090	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
XH93_RS29095	COG1696	Membrane protein involved in D-alanine export
XH93_RS29135	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XH93_RS29140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XH93_RS29155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XH93_RS29160	COG0110	maltose O-acetyltransferase activity
XH93_RS29175	COG0367	asparagine synthase
XH93_RS29185	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XH93_RS29185	COG2755	lipolytic protein G-D-S-L family
XH93_RS29190	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XH93_RS29215	COG4795	General secretion pathway protein
XH93_RS29220	COG2165	general secretion pathway protein
XH93_RS29235	COG1459	type II secretion system
XH93_RS29240	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XH93_RS29245	COG1450	Type ii and iii secretion system protein
XH93_RS29290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XH93_RS29305	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XH93_RS29310	COG2226	methyltransferase
XH93_RS29330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH93_RS29345	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
XH93_RS29350	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XH93_RS29355	COG3181	Tripartite tricarboxylate transporter family receptor
XH93_RS29365	COG1024	Enoyl-CoA hydratase
XH93_RS29370	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XH93_RS29375	COG2271	Major facilitator Superfamily
XH93_RS29380	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XH93_RS29390	COG0277	FAD linked oxidase domain protein
XH93_RS29390	COG0247	lactate metabolic process
XH93_RS29400	COG1024	Enoyl-CoA hydratase
XH93_RS29405	COG0243	molybdopterin cofactor binding
XH93_RS29430	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS29440	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XH93_RS29460	COG3181	Tripartite tricarboxylate transporter family receptor
XH93_RS29475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XH93_RS29485	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
XH93_RS29490	COG3842	ATPase activity
XH93_RS29500	COG4149	molybdate abc transporter
XH93_RS29510	COG1063	alcohol dehydrogenase
XH93_RS29570	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XH93_RS29640	COG1304	FMN binding
XH93_RS29645	COG4977	sequence-specific DNA binding
XH93_RS29655	COG2271	Major facilitator Superfamily
XH93_RS29660	COG3403	YqcI/YcgG family
XH93_RS29680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH93_RS29720	COG1472	Belongs to the glycosyl hydrolase 3 family
XH93_RS29730	COG0745	RESPONSE REGULATOR receiver
XH93_RS29735	COG2205	protein histidine kinase activity
XH93_RS29740	COG0183	Belongs to the thiolase family
XH93_RS29745	COG1024	Enoyl-CoA hydratase
XH93_RS29750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH93_RS29755	COG1131	(ABC) transporter
XH93_RS29785	COG1309	transcriptional regulator
XH93_RS29795	COG2072	flavoprotein involved in K transport
XH93_RS29810	COG0596	Alpha beta hydrolase
XH93_RS29825	COG3791	Glutathione-dependent formaldehyde-activating
XH93_RS29830	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
XH93_RS29865	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
XH93_RS29885	COG1131	(ABC) transporter
XH93_RS29930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XH93_RS29995	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XH93_RS30015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XH93_RS30020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XH93_RS30025	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XH93_RS30035	COG0243	molybdopterin cofactor binding
XH93_RS30040	COG2140	Oxalate decarboxylase
XH93_RS30045	COG0583	DNA-binding transcription factor activity
XH93_RS30050	COG0753	catalase activity
XH93_RS30070	COG2205	protein histidine kinase activity
XH93_RS30115	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XH93_RS30130	COG1609	Transcriptional regulator
XH93_RS30135	COG3485	protocatechuate 3,4-dioxygenase
XH93_RS30145	COG3246	L-lysine catabolic process to acetate
XH93_RS30150	COG3321	synthase
XH93_RS30150	COG0604	alcohol dehydrogenase
XH93_RS30170	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
XH93_RS30370	COG3278	Belongs to the heme-copper respiratory oxidase family
XH93_RS30385	COG2010	Cytochrome c
XH93_RS30410	COG0583	DNA-binding transcription factor activity
XH93_RS30415	COG1917	Cupin 2, conserved barrel domain protein
XH93_RS30415	COG1396	sequence-specific DNA binding
XH93_RS30420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XH93_RS30425	COG5433	transposase activity
XH93_RS30430	COG2326	polyphosphate kinase activity
XH93_RS30490	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS30535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XH93_RS30545	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XH93_RS30570	COG1125	glycine betaine transport
XH93_RS30570	COG0517	IMP dehydrogenase activity
XH93_RS30575	COG1174	glycine betaine transport
XH93_RS30600	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XH93_RS30610	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XH93_RS30630	COG0440	acetolactate synthase activity
XH93_RS30640	COG0028	Belongs to the TPP enzyme family
XH93_RS30645	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XH93_RS30650	COG0560	Phosphoserine phosphatase
XH93_RS30665	COG0330	HflC and HflK could
XH93_RS30670	COG0330	HflC and HflK could
XH93_RS30685	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
XH93_RS30725	COG0114	fumarate hydratase activity
XH93_RS30745	COG2124	cytochrome p450
XH93_RS30750	COG1309	transcriptional regulator
XH93_RS30755	COG2271	Major facilitator Superfamily
XH93_RS30780	COG1129	ABC transporter
XH93_RS30800	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XH93_RS30805	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
XH93_RS30810	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XH93_RS30815	COG2186	Transcriptional regulator
XH93_RS30820	COG0785	Cytochrome C biogenesis protein
XH93_RS30840	COG0277	FAD linked oxidase domain protein
XH93_RS30850	COG5487	UPF0391 membrane protein
XH93_RS30855	COG0210	DNA helicase
XH93_RS30870	COG1131	(ABC) transporter
XH93_RS30875	COG0842	Transport permease protein
XH93_RS30925	COG2264	protein methyltransferase activity
XH93_RS30940	COG0006	proline dipeptidase activity
XH93_RS30940	COG0006	proline dipeptidase activity
XH93_RS30945	COG2814	Major facilitator Superfamily
XH93_RS30950	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XH93_RS30960	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XH93_RS30970	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
XH93_RS30975	COG0849	cell division
XH93_RS30980	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XH93_RS30985	COG1181	Belongs to the D-alanine--D-alanine ligase family
XH93_RS30990	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XH93_RS30995	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XH93_RS31000	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XH93_RS31010	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
XH93_RS31015	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XH93_RS31025	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XH93_RS31040	COG0275	rRNA processing
XH93_RS31045	COG3023	N-Acetylmuramoyl-L-alanine amidase
XH93_RS31065	COG4941	Belongs to the sigma-70 factor family
XH93_RS31070	COG3795	YCII-related domain
XH93_RS31080	COG2200	EAL domain
XH93_RS31080	COG2199	diguanylate cyclase activity
XH93_RS31080	COG2202	Pas domain
XH93_RS31085	COG0583	DNA-binding transcription factor activity
XH93_RS31100	COG0596	Alpha beta hydrolase
XH93_RS31115	COG5265	(ABC) transporter
XH93_RS31130	COG1309	transcriptional regulator
XH93_RS31140	COG2072	flavoprotein involved in K transport
XH93_RS31150	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS31185	COG2917	probably involved in intracellular septation
XH93_RS31215	COG0457	Tetratricopeptide repeat
XH93_RS31215	COG3710	Transcriptional regulator
XH93_RS31225	COG0688	phosphatidylethanolamine metabolic process
XH93_RS31230	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XH93_RS31245	COG0438	transferase activity, transferring glycosyl groups
XH93_RS31265	COG1388	LysM domain
XH93_RS31265	COG1376	ErfK ybiS ycfS ynhG family protein
XH93_RS31280	COG3360	Dodecin
XH93_RS31345	COG2022	thiamine diphosphate biosynthetic process
XH93_RS31355	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
XH93_RS31400	COG2135	peptidase activity
XH93_RS31410	COG2816	NAD+ diphosphatase activity
XH93_RS31430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XH93_RS31435	COG0354	folic acid binding
XH93_RS31440	COG0519	Catalyzes the synthesis of GMP from XMP
XH93_RS31445	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
XH93_RS31470	COG0604	alcohol dehydrogenase
XH93_RS31490	COG0574	Belongs to the PEP-utilizing enzyme family
XH93_RS31490	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XH93_RS31515	COG0751	glycine-tRNA ligase activity
XH93_RS31520	COG0752	glycyl-tRNA synthetase alpha subunit
XH93_RS31545	COG0142	geranyltranstransferase activity
XH93_RS31560	COG4948	Mandelate Racemase Muconate Lactonizing
XH93_RS31605	COG2116	formate transmembrane transporter activity
XH93_RS31640	COG2207	Transcriptional regulator
XH93_RS31660	COG4948	Mandelate Racemase Muconate Lactonizing
XH93_RS31670	COG0386	Belongs to the glutathione peroxidase family
XH93_RS31675	COG0154	amidase activity
XH93_RS31700	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
XH93_RS31705	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
XH93_RS31710	COG0535	radical SAM domain protein
XH93_RS31715	COG0535	radical SAM domain protein
XH93_RS31735	COG0493	'glutamate synthase
XH93_RS31740	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
XH93_RS31740	COG0674	pyruvate-flavodoxin oxidoreductase activity
XH93_RS31745	COG1013	pyruvate-flavodoxin oxidoreductase activity
XH93_RS31760	COG2719	SpoVR family
XH93_RS31765	COG2718	Belongs to the UPF0229 family
XH93_RS31770	COG2766	serine protein kinase
XH93_RS31785	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XH93_RS31790	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XH93_RS31795	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XH93_RS31800	COG0363	glucosamine-6-phosphate deaminase activity
XH93_RS31805	COG3265	gluconokinase activity
XH93_RS31820	COG3387	PFAM Glycoside hydrolase 15-related
XH93_RS31825	COG1640	4-alpha-glucanotransferase
XH93_RS31830	COG0366	Alpha amylase catalytic
XH93_RS31835	COG0366	Alpha amylase catalytic
XH93_RS31840	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XH93_RS31850	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XH93_RS31875	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
XH93_RS31890	COG2205	protein histidine kinase activity
XH93_RS31895	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
XH93_RS31900	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XH93_RS31905	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XH93_RS31935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XH93_RS31945	COG0330	HflC and HflK could
XH93_RS31965	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
XH93_RS31980	COG0598	Magnesium transport protein CorA
XH93_RS31985	COG3383	formate dehydrogenase (NAD+) activity
XH93_RS31990	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XH93_RS32000	COG2223	nitrite transmembrane transporter activity
XH93_RS32010	COG0303	'Molybdopterin
XH93_RS32015	COG1763	Mo-molybdopterin cofactor biosynthetic process
XH93_RS32025	COG0746	molybdenum cofactor guanylyltransferase activity
XH93_RS32030	COG0303	'Molybdopterin
XH93_RS32075	COG0071	Belongs to the small heat shock protein (HSP20) family
XH93_RS32110	COG0625	glutathione transferase activity
XH93_RS32125	COG2376	Dihydroxyacetone kinase
XH93_RS32145	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
XH93_RS32150	COG1461	Dihydroxyacetone kinase
XH93_RS32170	COG0395	ABC-type sugar transport system, permease component
XH93_RS32175	COG1175	transmembrane transport
XH93_RS32200	COG1672	PFAM Archaeal ATPase
XH93_RS32200	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XH93_RS32240	COG1024	Enoyl-CoA hydratase
XH93_RS32245	COG0405	Gamma-glutamyltransferase
XH93_RS32260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XH93_RS32265	COG1126	abc transporter atp-binding protein
XH93_RS32270	COG0765	amino acid transport
XH93_RS32285	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XH93_RS32290	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XH93_RS32295	COG2080	2 iron, 2 sulfur cluster binding
XH93_RS32320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XH93_RS32325	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XH93_RS32330	COG3665	Urea carboxylase-associated protein
XH93_RS32350	COG0534	Mate efflux family protein
XH93_RS32355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XH93_RS32360	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XH93_RS32405	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XH93_RS32420	COG1595	DNA-templated transcription, initiation
XH93_RS32450	COG3766	membrane
XH93_RS32465	COG0754	glutathionylspermidine amidase activity
XH93_RS32475	COG2201	protein-glutamate methylesterase activity
XH93_RS32480	COG0784	Response regulator, receiver
XH93_RS32480	COG0643	Histidine kinase
XH93_RS32480	COG2198	Histidine kinase
XH93_RS32485	COG0835	chemotaxis
XH93_RS32490	COG2198	Histidine kinase
XH93_RS32490	COG0784	Response regulator, receiver
XH93_RS32490	COG0643	Histidine kinase
XH93_RS32560	COG0028	Belongs to the TPP enzyme family
XH93_RS32565	COG1376	ErfK ybiS ycfS ynhG family protein
XH93_RS32575	COG2207	Transcriptional regulator
XH93_RS32590	COG2267	carboxylic ester hydrolase activity
XH93_RS32605	COG0501	Belongs to the peptidase M48B family
XH93_RS32650	COG2226	methyltransferase
XH93_RS32660	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XH93_RS32670	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
XH93_RS32670	COG0028	Belongs to the TPP enzyme family
XH93_RS32675	COG0583	DNA-binding transcription factor activity
XH93_RS32680	COG1960	acyl-CoA dehydrogenase activity
XH93_RS32685	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH93_RS32690	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
XH93_RS32720	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XH93_RS32730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XH93_RS32750	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS32755	COG1272	protein, Hemolysin III
XH93_RS32760	COG3106	COG3106 Predicted ATPase
XH93_RS32765	COG3768	UPF0283 membrane protein
XH93_RS32805	COG5295	Hep Hag repeat protein
XH93_RS32810	COG2207	Transcriptional regulator
XH93_RS32820	COG1278	Cold shock
XH93_RS32840	COG0506	proline dehydrogenase activity
XH93_RS32840	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
XH93_RS32840	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
XH93_RS32870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XH93_RS32890	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
XH93_RS32895	COG1704	LemA family
XH93_RS32900	COG1024	Enoyl-CoA hydratase
XH93_RS32905	COG1960	acyl-CoA dehydrogenase activity
XH93_RS32910	COG1960	acyl-CoA dehydrogenase activity
XH93_RS32925	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XH93_RS32950	COG2273	Hydrolase Family 16
XH93_RS32950	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
XH93_RS32955	COG2723	6-phospho-beta-galactosidase activity
XH93_RS32960	COG1454	alcohol dehydrogenase
XH93_RS32990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XH93_RS32995	COG2197	response regulator
XH93_RS33000	COG5002	protein histidine kinase activity
XH93_RS33020	COG2183	response to ionizing radiation
XH93_RS33055	COG1024	Enoyl-CoA hydratase
XH93_RS33060	COG2030	dehydratase
XH93_RS33060	COG1012	belongs to the aldehyde dehydrogenase family
XH93_RS33070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XH93_RS33090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XH93_RS33100	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
XH93_RS33115	COG1764	response to oxidative stress
XH93_RS33185	COG1250	3-hydroxyacyl-CoA dehydrogenase
XH93_RS33195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XH93_RS33200	COG0179	Fumarylacetoacetate (FAA) hydrolase
XH93_RS33210	COG1960	acyl-CoA dehydrogenase activity
XH93_RS33235	COG4638	Rieske (2fe-2S)
XH93_RS33275	COG1858	cytochrome C peroxidase
XH93_RS33300	COG2814	Major facilitator Superfamily
XH93_RS33305	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XH93_RS33315	COG0583	DNA-binding transcription factor activity
XH93_RS33330	COG1129	ABC transporter
XH93_RS33335	COG1172	Belongs to the binding-protein-dependent transport system permease family
XH93_RS33340	COG1172	Belongs to the binding-protein-dependent transport system permease family
XH93_RS33350	COG1609	Transcriptional regulator
XH93_RS33365	COG2010	Cytochrome c
XH93_RS33365	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XH93_RS33375	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XH93_RS33415	COG0583	DNA-binding transcription factor activity
XH93_RS33445	COG1129	ABC transporter
XH93_RS33460	COG0683	leucine binding
XH93_RS33465	COG5002	protein histidine kinase activity
XH93_RS33465	COG0784	Response regulator, receiver
XH93_RS33465	COG2198	Histidine kinase
XH93_RS33470	COG0745	RESPONSE REGULATOR receiver
XH93_RS33490	COG0653	protein targeting
XH93_RS33495	COG4733	cellulase activity
XH93_RS33495	COG5297	Belongs to the glycosyl hydrolase family 6
XH93_RS33500	COG1309	transcriptional regulator
XH93_RS33520	COG1022	Amp-dependent synthetase and ligase
XH93_RS33540	COG1960	acyl-CoA dehydrogenase activity
XH93_RS33550	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS33565	COG4638	Rieske (2fe-2S)
XH93_RS33570	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH93_RS33575	COG0778	Nitroreductase
XH93_RS33590	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS33595	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS33600	COG0318	PFAM AMP-dependent synthetase and ligase
XH93_RS33630	COG0559	Belongs to the binding-protein-dependent transport system permease family
XH93_RS33655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH93_RS33665	COG1960	acyl-CoA dehydrogenase activity
XH93_RS33675	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
XH93_RS33680	COG3246	L-lysine catabolic process to acetate
XH93_RS33685	COG1960	acyl-CoA dehydrogenase activity
XH93_RS33695	COG2301	Belongs to the HpcH HpaI aldolase family
XH93_RS33700	COG2030	dehydratase
XH93_RS33705	COG2130	NADP-dependent
XH93_RS33715	COG1024	Enoyl-CoA hydratase
XH93_RS33715	COG1250	3-hydroxyacyl-CoA dehydrogenase
XH93_RS33720	COG0318	PFAM AMP-dependent synthetase and ligase
XH93_RS33725	COG1024	Enoyl-CoA hydratase
XH93_RS33730	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS33740	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS33745	COG2030	dehydratase
XH93_RS33750	COG3181	Tripartite tricarboxylate transporter family receptor
XH93_RS33765	COG0446	pyridine nucleotide-disulphide oxidoreductase
XH93_RS33780	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS33810	COG0729	surface antigen
XH93_RS33825	COG3064	Membrane
XH93_RS33880	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XH93_RS33885	COG4566	intracellular signal transduction
XH93_RS33895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XH93_RS33905	COG0628	permease
XH93_RS33925	COG2985	domain, Protein
XH93_RS33940	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS33950	COG1137	ATPase activity
XH93_RS34050	COG1177	transmembrane transport
XH93_RS34085	COG2963	transposase activity
XH93_RS34090	COG3436	PFAM IS66 Orf2 family protein
XH93_RS34095	COG2433	Pfam Transposase IS66
XH93_RS34100	COG3318	Belongs to the UPF0149 family
XH93_RS34110	COG3012	SEC-C Motif Domain Protein
XH93_RS34115	COG2433	Pfam Transposase IS66
XH93_RS34120	COG3436	PFAM IS66 Orf2 family protein
XH93_RS34125	COG2963	transposase activity
XH93_RS34190	COG3550	peptidyl-serine autophosphorylation
XH93_RS34195	COG1960	acyl-CoA dehydrogenase activity
XH93_RS34200	COG0410	ABC transporter
XH93_RS34255	COG0009	L-threonylcarbamoyladenylate synthase
XH93_RS34260	COG0277	FAD linked oxidase domain protein
XH93_RS34270	COG0494	nUDIX hydrolase
XH93_RS34290	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS34295	COG2204	response regulator
XH93_RS34325	COG0640	Transcriptional regulator
XH93_RS34335	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XH93_RS34405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XH93_RS34415	COG1376	ErfK ybiS ycfS ynhG family protein
XH93_RS34425	COG2897	thiosulfate sulfurtransferase activity
XH93_RS34440	COG3706	GGDEF domain
XH93_RS34440	COG2203	Gaf domain
XH93_RS34440	COG4251	negative regulation of phosphorylation
XH93_RS34440	COG5001	Diguanylate cyclase
XH93_RS34445	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XH93_RS34450	COG2072	flavoprotein involved in K transport
XH93_RS34470	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
XH93_RS34485	COG1573	uracil-dna glycosylase
XH93_RS34495	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
XH93_RS34515	COG1846	Transcriptional regulator
XH93_RS34515	COG0456	acetyltransferase
XH93_RS34525	COG0521	Mo-molybdopterin cofactor biosynthetic process
XH93_RS34530	COG2321	neutral zinc metallopeptidase
XH93_RS34535	COG2189	Belongs to the N(4) N(6)-methyltransferase family
XH93_RS34545	COG0625	glutathione transferase activity
XH93_RS34560	COG0625	glutathione transferase activity
XH93_RS34580	COG1194	a g-specific adenine glycosylase
XH93_RS34600	COG1196	nuclear chromosome segregation
XH93_RS34620	COG1704	LemA family
XH93_RS34640	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XH93_RS34660	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XH93_RS34660	COG2857	Cytochrome c1
XH93_RS34665	COG0723	plastoquinol--plastocyanin reductase activity
XH93_RS34670	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XH93_RS34675	COG0602	queuosine metabolic process
XH93_RS34685	COG0408	coproporphyrinogen oxidase activity
XH93_RS34690	COG0546	phosphoglycolate phosphatase activity
XH93_RS34700	COG0617	tRNA 3'-terminal CCA addition
XH93_RS34720	COG0714	Associated with various cellular activities
XH93_RS34745	COG4771	TonB-dependent receptor
XH93_RS34760	COG1051	belongs to the nudix hydrolase family
XH93_RS34815	COG0667	Aldo Keto reductase
XH93_RS34820	COG0501	Belongs to the peptidase M48B family
XH93_RS34850	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS34855	COG1902	pentaerythritol trinitrate reductase activity
XH93_RS34870	COG0395	ABC-type sugar transport system, permease component
XH93_RS34880	COG3842	ATPase activity
XH93_RS34885	COG3842	ATPase activity
XH93_RS34895	COG1349	DNA-binding transcription factor activity
XH93_RS34905	COG1607	acyl-coa hydrolase
XH93_RS34910	COG1024	Enoyl-CoA hydratase
XH93_RS34910	COG1250	3-hydroxyacyl-CoA dehydrogenase
XH93_RS34940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XH93_RS34955	COG3214	Protein conserved in bacteria
XH93_RS34960	COG3047	cAMP biosynthetic process
XH93_RS34960	COG2885	chlorophyll binding
XH93_RS34995	COG1024	Enoyl-CoA hydratase
XH93_RS35005	COG3237	CsbD-like
XH93_RS35010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XH93_RS35020	COG0405	Gamma-glutamyltransferase
XH93_RS35025	COG1054	Belongs to the UPF0176 family
XH93_RS35030	COG2900	Belongs to the SlyX family
XH93_RS35060	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XH93_RS35070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XH93_RS35080	COG5001	Diguanylate cyclase
XH93_RS35080	COG3300	MHYT domain
XH93_RS35105	COG5001	Diguanylate cyclase
XH93_RS35105	COG5002	protein histidine kinase activity
XH93_RS35125	COG2171	N-acyltransferase activity
XH93_RS35140	COG1024	Enoyl-CoA hydratase
XH93_RS35145	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS35160	COG1309	transcriptional regulator
XH93_RS35165	COG3386	PFAM SMP-30 Gluconolaconase
XH93_RS35200	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XH93_RS35205	COG2271	Major facilitator Superfamily
XH93_RS35210	COG0583	DNA-binding transcription factor activity
XH93_RS35215	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XH93_RS35220	COG4948	Mandelate Racemase Muconate Lactonizing
XH93_RS35225	COG1012	belongs to the aldehyde dehydrogenase family
XH93_RS35230	COG2721	sulfolactate sulfo-lyase activity
XH93_RS35235	COG3025	triphosphatase activity
XH93_RS35245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XH93_RS35250	COG1116	anion transmembrane transporter activity
XH93_RS35260	COG0473	3-isopropylmalate dehydrogenase activity
XH93_RS35265	COG0066	3-isopropylmalate dehydratase activity
XH93_RS35270	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XH93_RS35280	COG0686	Belongs to the AlaDH PNT family
XH93_RS35285	COG1522	sequence-specific DNA binding
XH93_RS35295	COG0519	Catalyzes the synthesis of GMP from XMP
XH93_RS35295	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XH93_RS35300	COG0583	DNA-binding transcription factor activity
XH93_RS35310	COG2159	amidohydrolase
XH93_RS35315	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XH93_RS35325	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
XH93_RS35330	COG0583	DNA-binding transcription factor activity
XH93_RS35350	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XH93_RS35370	COG1960	acyl-CoA dehydrogenase activity
XH93_RS35375	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS35405	COG5441	Belongs to the UPF0261 family
XH93_RS35410	COG5564	TIM-barrel signal transduction protein
XH93_RS35415	COG2268	Band 7 protein
XH93_RS35415	COG2268	Band 7 protein
XH93_RS35460	COG3618	amidohydrolase
XH93_RS35470	COG3386	PFAM SMP-30 Gluconolaconase
XH93_RS35475	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XH93_RS35495	COG4948	Mandelate Racemase Muconate Lactonizing
XH93_RS35500	COG1473	amidohydrolase
XH93_RS35510	COG0601	transmembrane transport
XH93_RS35515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH93_RS35520	COG0444	Belongs to the ABC transporter superfamily
XH93_RS35525	COG4608	Belongs to the ABC transporter superfamily
XH93_RS35540	COG0747	negative chemotaxis
XH93_RS35545	COG4608	Belongs to the ABC transporter superfamily
XH93_RS35550	COG0444	Belongs to the ABC transporter superfamily
XH93_RS35555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH93_RS35580	COG1069	ribulokinase activity
XH93_RS35585	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS35635	COG0484	heat shock protein binding
XH93_RS35645	COG0542	response to heat
XH93_RS35650	COG2837	iron assimilation
XH93_RS35680	COG3573	Dehydrogenase
XH93_RS35695	COG0438	transferase activity, transferring glycosyl groups
XH93_RS35725	COG1454	alcohol dehydrogenase
XH93_RS35730	COG1024	Enoyl-CoA hydratase
XH93_RS35740	COG0183	Belongs to the thiolase family
XH93_RS35750	COG1960	acyl-CoA dehydrogenase activity
XH93_RS35760	COG0318	PFAM AMP-dependent synthetase and ligase
XH93_RS35780	COG0384	phenazine biosynthesis protein PhzF
XH93_RS35785	COG0596	Alpha beta hydrolase
XH93_RS35850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XH93_RS35865	COG1615	UPF0182 protein
XH93_RS35880	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS35885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XH93_RS35895	COG0583	DNA-binding transcription factor activity
XH93_RS35905	COG3920	Histidine kinase
XH93_RS35915	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XH93_RS35915	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
XH93_RS35920	COG4191	Histidine kinase
XH93_RS35925	COG0583	DNA-binding transcription factor activity
XH93_RS35940	COG4191	Histidine kinase
XH93_RS35940	COG0784	Response regulator, receiver
XH93_RS35960	COG4191	Histidine kinase
XH93_RS35965	COG4566	intracellular signal transduction
XH93_RS35970	COG4566	intracellular signal transduction
XH93_RS35975	COG0583	DNA-binding transcription factor activity
XH93_RS35995	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XH93_RS36020	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XH93_RS36060	COG3474	cytochrome
XH93_RS36080	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XH93_RS36095	COG0604	alcohol dehydrogenase
XH93_RS36105	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XH93_RS36105	COG2010	Cytochrome c
XH93_RS36125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XH93_RS36160	COG0477	Major facilitator Superfamily
XH93_RS36200	COG2217	Heavy metal translocating P-type atpase
XH93_RS36215	COG2010	Cytochrome c
XH93_RS36230	COG3278	Belongs to the heme-copper respiratory oxidase family
XH93_RS36255	COG4191	Histidine kinase
XH93_RS36260	COG4566	intracellular signal transduction
XH93_RS36285	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
XH93_RS36295	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XH93_RS36295	COG3218	ABC-type transport auxiliary lipoprotein component
XH93_RS36300	COG1127	ABC transporter
XH93_RS36305	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XH93_RS36315	COG0045	succinate-CoA ligase (ADP-forming) activity
XH93_RS36315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XH93_RS36315	COG1042	CoA-binding domain protein
XH93_RS36320	COG4109	DRTGG domain
XH93_RS36325	COG0071	Belongs to the small heat shock protein (HSP20) family
XH93_RS36355	COG3243	poly(R)-hydroxyalkanoic acid synthase
XH93_RS36385	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
XH93_RS36395	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XH93_RS36410	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
XH93_RS36415	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
XH93_RS36435	COG0589	response to stress
XH93_RS36445	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XH93_RS36455	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XH93_RS36485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XH93_RS36505	COG0517	IMP dehydrogenase activity
XH93_RS36505	COG0617	tRNA 3'-terminal CCA addition
XH93_RS36505	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
XH93_RS36515	COG0563	adenylate kinase activity
XH93_RS36520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XH93_RS36525	COG3162	membrane
XH93_RS36530	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XH93_RS36540	COG2176	DNA-directed DNA polymerase activity
XH93_RS36560	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XH93_RS36565	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XH93_RS36575	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XH93_RS36580	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
XH93_RS36615	COG3920	Histidine kinase
XH93_RS36650	COG1733	regulation of RNA biosynthetic process
XH93_RS36675	COG1793	dna ligase
XH93_RS36790	COG1793	dna ligase
XH93_RS36795	COG3729	General stress protein
XH93_RS36825	COG3546	catalase activity
XH93_RS36835	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
XH93_RS36835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XH93_RS36840	COG0723	plastoquinol--plastocyanin reductase activity
XH93_RS36840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XH93_RS36845	COG3685	Protein conserved in bacteria
XH93_RS36850	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XH93_RS36865	COG1335	isochorismatase
XH93_RS36870	COG0671	phosphoesterase, PA-phosphatase related
XH93_RS36905	COG0745	RESPONSE REGULATOR receiver
XH93_RS36915	COG1295	ribonuclease BN
XH93_RS36950	COG0583	DNA-binding transcription factor activity
XH93_RS36955	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS36960	COG3959	Transketolase, thiamine diphosphate binding domain
XH93_RS36965	COG3958	Transketolase
XH93_RS36970	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XH93_RS37010	COG0482	sulfurtransferase activity
XH93_RS37020	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XH93_RS37060	COG1766	The M ring may be actively involved in energy transduction
XH93_RS37065	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
XH93_RS37075	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
XH93_RS37080	COG2204	response regulator
XH93_RS37110	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XH93_RS37115	COG1116	anion transmembrane transporter activity
XH93_RS37125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XH93_RS37130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XH93_RS37135	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XH93_RS37140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XH93_RS37145	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XH93_RS37150	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XH93_RS37155	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XH93_RS37190	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XH93_RS37195	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XH93_RS37205	COG0583	DNA-binding transcription factor activity
XH93_RS37220	COG3218	ABC-type transport auxiliary lipoprotein component
XH93_RS37220	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XH93_RS37225	COG1304	FMN binding
XH93_RS37255	COG0583	DNA-binding transcription factor activity
XH93_RS37275	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XH93_RS37285	COG1175	transmembrane transport
XH93_RS37290	COG0395	ABC-type sugar transport system, permease component
XH93_RS37300	COG0848	biopolymer transport protein
XH93_RS37320	COG4771	TonB-dependent receptor
XH93_RS37330	COG4558	Periplasmic binding protein
XH93_RS37335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XH93_RS37340	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
XH93_RS37355	COG0477	Major facilitator Superfamily
XH93_RS37365	COG0183	Belongs to the thiolase family
XH93_RS37370	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XH93_RS37390	COG0625	glutathione transferase activity
XH93_RS37405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XH93_RS37415	COG1304	FMN binding
XH93_RS37430	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XH93_RS37440	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XH93_RS37455	COG0436	Aminotransferase
XH93_RS37460	COG0625	glutathione transferase activity
XH93_RS37490	COG0667	Aldo Keto reductase
XH93_RS37495	COG2852	Protein conserved in bacteria
XH93_RS37510	COG0546	phosphoglycolate phosphatase activity
XH93_RS37520	COG1024	Enoyl-CoA hydratase
XH93_RS37525	COG0625	glutathione transferase activity
XH93_RS37530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XH93_RS37535	COG1999	signal sequence binding
XH93_RS37565	COG0556	nucleotide-excision repair
XH93_RS37625	COG2030	dehydratase
XH93_RS37640	COG1192	Involved in chromosome partitioning
XH93_RS37695	COG2205	protein histidine kinase activity
XH93_RS37705	COG1802	Transcriptional regulator
XH93_RS37710	COG1012	belongs to the aldehyde dehydrogenase family
XH93_RS37715	COG2814	Major facilitator Superfamily
XH93_RS37770	COG1175	transmembrane transport
XH93_RS37780	COG1177	transmembrane transport
XH93_RS37785	COG1176	ABC-type spermidine putrescine transport system, permease component I
XH93_RS37790	COG3842	ATPase activity
XH93_RS37810	COG0488	(ABC) transporter
XH93_RS37815	COG3300	MHYT domain
XH93_RS37815	COG5001	Diguanylate cyclase
XH93_RS37845	COG3447	MASE1 domain protein
XH93_RS37845	COG5001	Diguanylate cyclase
XH93_RS37845	COG5002	protein histidine kinase activity
XH93_RS37855	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
XH93_RS37860	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XH93_RS37865	COG0828	Belongs to the bacterial ribosomal protein bS21 family
XH93_RS37885	COG0387	Pfam Sodium calcium exchanger
XH93_RS37930	COG1164	Oligoendopeptidase f
XH93_RS37935	COG2204	response regulator
XH93_RS37940	COG2989	Protein conserved in bacteria
XH93_RS37955	COG3750	Belongs to the UPF0335 family
XH93_RS37970	COG0469	pyruvate kinase activity
XH93_RS37975	COG1764	response to oxidative stress
XH93_RS37980	COG1309	transcriptional regulator
XH93_RS37995	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XH93_RS38000	COG0037	tRNA processing
XH93_RS38010	COG2885	chlorophyll binding
XH93_RS38020	COG5001	Diguanylate cyclase
XH93_RS38025	COG0823	Involved in the tonB-independent uptake of proteins
XH93_RS38035	COG0848	biopolymer transport protein
XH93_RS38045	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XH93_RS38050	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XH93_RS38075	COG0326	Molecular chaperone. Has ATPase activity
XH93_RS38080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XH93_RS38085	COG0252	asparaginase activity
XH93_RS38090	COG1960	acyl-CoA dehydrogenase activity
XH93_RS38110	COG1846	Transcriptional regulator
XH93_RS38145	COG1684	flagellar biosynthetic protein fliR
XH93_RS38150	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XH93_RS38155	COG4794	Type iii secretion
XH93_RS38160	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XH93_RS38165	COG5443	negative regulation of bacterial-type flagellum assembly
XH93_RS38185	COG1749	Flagellar hook protein flgE
XH93_RS38205	COG1360	Flagellar Motor Protein
XH93_RS38220	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XH93_RS38225	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XH93_RS38230	COG1338	Plays a role in the flagellum-specific transport system
XH93_RS38240	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
XH93_RS38250	COG1706	bacterial-type flagellum-dependent cell motility
XH93_RS38260	COG4786	Flagellar basal body rod
XH93_RS38265	COG1677	Flagellar hook-basal body complex protein FliE
XH93_RS38270	COG1558	bacterial-type flagellum-dependent cell motility
XH93_RS38275	COG1815	bacterial-type flagellum-dependent cell motility
XH93_RS38280	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XH93_RS38285	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
XH93_RS38290	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
XH93_RS38305	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XH93_RS38315	COG4786	Flagellar basal body rod
XH93_RS38320	COG1157	protein secretion by the type III secretion system
XH93_RS38325	COG1846	Transcriptional regulator
XH93_RS38330	COG3665	Urea carboxylase-associated protein
XH93_RS38335	COG0251	oxidation-reduction process
XH93_RS38345	COG0765	amino acid transport
XH93_RS38350	COG0765	amino acid transport
XH93_RS38355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XH93_RS38360	COG0778	Nitroreductase
XH93_RS38370	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XH93_RS38405	COG3845	ABC transporter
XH93_RS38410	COG4603	Belongs to the binding-protein-dependent transport system permease family
XH93_RS38415	COG1079	Belongs to the binding-protein-dependent transport system permease family
XH93_RS38435	COG2080	2 iron, 2 sulfur cluster binding
XH93_RS38435	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XH93_RS38455	COG4608	Belongs to the ABC transporter superfamily
XH93_RS38460	COG0444	Belongs to the ABC transporter superfamily
XH93_RS38465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH93_RS38470	COG0601	transmembrane transport
XH93_RS38475	COG0747	negative chemotaxis
XH93_RS38500	COG0402	S-adenosylhomocysteine deaminase activity
XH93_RS38520	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
XH93_RS38545	COG3842	ATPase activity
XH93_RS38555	COG1176	ABC-type spermidine putrescine transport system, permease component I
XH93_RS38560	COG1177	transmembrane transport
XH93_RS38585	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS38605	COG0179	Fumarylacetoacetate (FAA) hydrolase
XH93_RS38615	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
XH93_RS38640	COG1595	DNA-templated transcription, initiation
XH93_RS38655	COG5285	phytanoyl-CoA dioxygenase
XH93_RS38670	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
XH93_RS38705	COG0739	heme binding
XH93_RS38725	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XH93_RS38730	COG0542	response to heat
XH93_RS38735	COG1396	sequence-specific DNA binding
XH93_RS38755	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XH93_RS38760	COG2813	Specifically methylates the guanine in position
XH93_RS38760	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XH93_RS38765	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XH93_RS38775	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XH93_RS38780	COG0287	Prephenate dehydrogenase
XH93_RS38840	COG1012	belongs to the aldehyde dehydrogenase family
XH93_RS38910	COG2884	Cell division ATP-binding protein ftsE
XH93_RS38920	COG2204	response regulator
XH93_RS38930	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XH93_RS38950	COG0019	diaminopimelate decarboxylase activity
XH93_RS38960	COG0165	Argininosuccinate lyase
XH93_RS38965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XH93_RS38975	COG1250	3-hydroxyacyl-CoA dehydrogenase
XH93_RS38980	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
XH93_RS38985	COG2086	electron transfer activity
XH93_RS39005	COG5002	protein histidine kinase activity
XH93_RS39005	COG2205	protein histidine kinase activity
XH93_RS39005	COG0784	Response regulator, receiver
XH93_RS39010	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XH93_RS39090	COG2072	flavoprotein involved in K transport
XH93_RS39100	COG0038	chloride channel
XH93_RS39120	COG4774	siderophore transport
XH93_RS39130	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
XH93_RS39140	COG1132	(ABC) transporter
XH93_RS39145	COG0254	rRNA binding
XH93_RS39150	COG1280	lysine exporter protein (LysE YggA)
XH93_RS39185	COG2203	Gaf domain
XH93_RS39185	COG5001	Diguanylate cyclase
XH93_RS39185	COG3706	GGDEF domain
XH93_RS39185	COG4251	negative regulation of phosphorylation
XH93_RS39195	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XH93_RS39200	COG2951	lytic endotransglycosylase activity
XH93_RS39210	COG3237	CsbD-like
XH93_RS39215	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS39220	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS39230	COG1678	Uncharacterized ACR, COG1678
XH93_RS39245	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS39265	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XH93_RS39270	COG4208	sulfate ABC transporter
XH93_RS39275	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XH93_RS39280	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XH93_RS39285	COG0175	sulfate reduction
XH93_RS39295	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XH93_RS39305	COG1648	precorrin-2 dehydrogenase activity
XH93_RS39305	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XH93_RS39310	COG0175	sulfate reduction
XH93_RS39320	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XH93_RS39340	COG1376	ErfK ybiS ycfS ynhG family protein
XH93_RS39340	COG1388	LysM domain
XH93_RS39345	COG0628	permease
XH93_RS39365	COG1846	Transcriptional regulator
XH93_RS39370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XH93_RS39380	COG0179	Fumarylacetoacetate (FAA) hydrolase
XH93_RS39405	COG2207	Transcriptional regulator
XH93_RS39430	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XH93_RS39460	COG2124	cytochrome p450
XH93_RS39465	COG0784	Response regulator, receiver
XH93_RS39480	COG5001	Diguanylate cyclase
XH93_RS39480	COG3300	MHYT domain
XH93_RS39500	COG1858	cytochrome C peroxidase
XH93_RS39510	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
XH93_RS39515	COG0830	nickel cation binding
XH93_RS39520	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
XH93_RS39535	COG0804	urea catabolic process
XH93_RS39540	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XH93_RS39545	COG2852	Protein conserved in bacteria
XH93_RS39550	COG0832	Belongs to the urease beta subunit family
XH93_RS39555	COG0831	urea catabolic process
XH93_RS39560	COG0829	nickel cation binding
XH93_RS39590	COG0513	Belongs to the DEAD box helicase family
XH93_RS39595	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
XH93_RS39600	COG1278	Cold shock
XH93_RS39620	COG2755	lipolytic protein G-D-S-L family
XH93_RS39620	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XH93_RS39640	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XH93_RS39650	COG4964	Belongs to the GSP D family
XH93_RS39685	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XH93_RS39695	COG4172	Belongs to the ABC transporter superfamily
XH93_RS39700	COG4239	(ABC) transporter, permease
XH93_RS39705	COG4174	ABC transporter (Permease)
XH93_RS39710	COG4166	transmembrane transport
XH93_RS39715	COG4166	transmembrane transport
XH93_RS39720	COG3474	cytochrome
XH93_RS39725	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XH93_RS39730	COG1605	Chorismate mutase
XH93_RS39730	COG0077	Prephenate dehydratase
XH93_RS39735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XH93_RS39775	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XH93_RS39795	COG2967	ApaG domain
XH93_RS39805	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XH93_RS39810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XH93_RS39820	COG0745	RESPONSE REGULATOR receiver
XH93_RS39825	COG0704	Plays a role in the regulation of phosphate uptake
XH93_RS39830	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XH93_RS39835	COG0581	inorganic phosphate transmembrane transporter activity
XH93_RS39840	COG0573	inorganic phosphate transmembrane transporter activity
XH93_RS39845	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XH93_RS39850	COG5002	protein histidine kinase activity
XH93_RS39865	COG0596	Alpha beta hydrolase
XH93_RS39880	COG1360	Flagellar Motor Protein
XH93_RS39915	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XH93_RS39920	COG1414	Transcriptional regulator
XH93_RS39945	COG4177	L-phenylalanine transmembrane transporter activity
XH93_RS39965	COG1595	DNA-templated transcription, initiation
XH93_RS39975	COG0477	Major facilitator Superfamily
XH93_RS39980	COG1252	NADH dehydrogenase
XH93_RS39990	COG2124	cytochrome p450
XH93_RS40015	COG1802	Transcriptional regulator
XH93_RS40035	COG4172	Belongs to the ABC transporter superfamily
XH93_RS40040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH93_RS40045	COG0601	transmembrane transport
XH93_RS40065	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XH93_RS40070	COG4191	Histidine kinase
XH93_RS40070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XH93_RS40075	COG0784	Response regulator, receiver
XH93_RS40075	COG3437	response regulator, receiver
XH93_RS40085	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XH93_RS40085	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XH93_RS40090	COG1280	lysine exporter protein (LysE YggA)
XH93_RS40100	COG0625	glutathione transferase activity
XH93_RS40105	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XH93_RS40130	COG0058	SHG alpha-glucan phosphorylase activity
XH93_RS40145	COG0010	Belongs to the arginase family
XH93_RS40150	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
XH93_RS40165	COG0745	RESPONSE REGULATOR receiver
XH93_RS40170	COG2205	protein histidine kinase activity
XH93_RS40180	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
XH93_RS40180	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
XH93_RS40185	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XH93_RS40195	COG0481	GTPase activity
XH93_RS40210	COG2223	nitrite transmembrane transporter activity
XH93_RS40215	COG1960	acyl-CoA dehydrogenase activity
XH93_RS40245	COG0840	transmembrane signaling receptor activity
XH93_RS40270	COG5001	Diguanylate cyclase
XH93_RS40280	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
XH93_RS40295	COG0725	ABC transporter, periplasmic molybdate-binding protein
XH93_RS40300	COG4149	molybdate abc transporter
XH93_RS40305	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XH93_RS40315	COG3263	regulation of cellular component size
XH93_RS40320	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
XH93_RS40320	COG3264	Mechanosensitive ion channel
XH93_RS40325	COG0024	Methionine aminopeptidase
XH93_RS40335	COG2003	Belongs to the UPF0758 family
XH93_RS40340	COG4941	Belongs to the sigma-70 factor family
XH93_RS40355	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XH93_RS40370	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XH93_RS40405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XH93_RS40410	COG0069	glutamate synthase activity
XH93_RS40435	COG1301	dicarboxylic acid transport
XH93_RS40440	COG2130	NADP-dependent
XH93_RS40510	COG5433	transposase activity
XH93_RS40525	COG0625	glutathione transferase activity
XH93_RS40550	COG0445	tRNA wobble uridine modification
XH93_RS40565	COG1024	Enoyl-CoA hydratase
XH93_RS40570	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XH93_RS40610	COG2010	Cytochrome c
XH93_RS40615	COG1027	Aspartate ammonia-lyase
XH93_RS40630	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH93_RS40665	COG3485	protocatechuate 3,4-dioxygenase
XH93_RS40685	COG0583	DNA-binding transcription factor activity
XH93_RS40725	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XH93_RS40750	COG1960	acyl-CoA dehydrogenase activity
XH93_RS40755	COG1024	Enoyl-CoA hydratase
XH93_RS40770	COG1024	Enoyl-CoA hydratase
XH93_RS40795	COG0477	Major facilitator Superfamily
XH93_RS40800	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XH93_RS40805	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XH93_RS40810	COG1845	cytochrome c oxidase, subunit III
XH93_RS40815	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XH93_RS40830	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XH93_RS40850	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XH93_RS40855	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
XH93_RS40870	COG0227	Belongs to the bacterial ribosomal protein bL28 family
XH93_RS40900	COG0657	acetylesterase activity
XH93_RS40935	COG1902	pentaerythritol trinitrate reductase activity
XH93_RS40960	COG0586	Pfam SNARE associated Golgi protein
XH93_RS40965	COG0372	Belongs to the citrate synthase family
XH93_RS40970	COG0372	Belongs to the citrate synthase family
XH93_RS40990	COG4536	flavin adenine dinucleotide binding
XH93_RS40995	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XH93_RS41000	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XH93_RS41010	COG4974	Belongs to the 'phage' integrase family
XH93_RS41015	COG0825	malonyl-CoA metabolic process
XH93_RS41020	COG3034	peptidoglycan biosynthetic process
XH93_RS41050	COG1129	ABC transporter
XH93_RS41090	COG0653	protein targeting
XH93_RS41095	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XH93_RS41100	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
XH93_RS41120	COG1040	competence protein
XH93_RS41125	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
XH93_RS41130	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XH93_RS41145	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XH93_RS41160	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
XH93_RS41165	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XH93_RS41180	COG2890	protein-(glutamine-N5) methyltransferase activity
XH93_RS41195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XH93_RS41205	COG0697	spore germination
XH93_RS41220	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
XH93_RS41235	COG3300	MHYT domain
XH93_RS41235	COG5001	Diguanylate cyclase
XH93_RS41250	COG0333	Belongs to the bacterial ribosomal protein bL32 family
XH93_RS41255	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XH93_RS41260	COG0142	geranyltranstransferase activity
XH93_RS41275	COG2897	thiosulfate sulfurtransferase activity
XH93_RS41280	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XH93_RS41285	COG2175	clavaminate synthase activity
XH93_RS41310	COG0735	belongs to the Fur family
XH93_RS41320	COG1566	PFAM secretion protein HlyD family protein
XH93_RS41335	COG0673	inositol 2-dehydrogenase activity
XH93_RS41340	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XH93_RS41345	COG3485	protocatechuate 3,4-dioxygenase
XH93_RS41350	COG3485	protocatechuate 3,4-dioxygenase
XH93_RS41355	COG0183	Belongs to the thiolase family
XH93_RS41360	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XH93_RS41380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XH93_RS41390	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XH93_RS41415	COG4566	intracellular signal transduction
XH93_RS41420	COG4566	intracellular signal transduction
XH93_RS41455	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XH93_RS41475	COG1131	(ABC) transporter
XH93_RS41485	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XH93_RS41505	COG0366	Alpha amylase catalytic
XH93_RS41515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XH93_RS41525	COG0477	Major facilitator Superfamily
XH93_RS41535	COG1028	Short-chain dehydrogenase reductase Sdr
XH93_RS41545	COG5001	Diguanylate cyclase
XH93_RS41545	COG3300	MHYT domain
XH93_RS41560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XH93_RS41570	COG0489	protein tyrosine kinase activity
XH93_RS41585	COG1902	pentaerythritol trinitrate reductase activity
XH93_RS41640	COG2902	Dehydrogenase
XH93_RS41650	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XH93_RS41655	COG2207	Transcriptional regulator
XH93_RS41660	COG2807	transmembrane transport
XH93_RS41715	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XH93_RS41720	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XH93_RS41800	COG0412	Dienelactone hydrolase
XH93_RS41805	COG1596	polysaccharide export
XH93_RS41810	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XH93_RS41820	COG0268	Binds directly to 16S ribosomal RNA