locus-tag	class	description
XH83_RS00015	COG2852	Protein conserved in bacteria
XH83_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XH83_RS00055	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XH83_RS00060	COG0534	Mate efflux family protein
XH83_RS00095	COG1741	Belongs to the pirin family
XH83_RS00100	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XH83_RS00125	COG0318	PFAM AMP-dependent synthetase and ligase
XH83_RS00130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XH83_RS00140	COG0180	Tryptophanyl-tRNA synthetase
XH83_RS00160	COG1214	PFAM Peptidase M22, glycoprotease
XH83_RS00160	COG0456	acetyltransferase
XH83_RS00170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XH83_RS00175	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XH83_RS00180	COG1702	phosphate starvation-inducible protein PhoH
XH83_RS00185	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XH83_RS00190	COG1253	flavin adenine dinucleotide binding
XH83_RS00195	COG0815	Transfers the fatty acyl group on membrane lipoproteins
XH83_RS00200	COG1396	sequence-specific DNA binding
XH83_RS00205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XH83_RS00210	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XH83_RS00220	COG0779	Required for maturation of 30S ribosomal subunits
XH83_RS00235	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XH83_RS00240	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XH83_RS00245	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XH83_RS00250	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XH83_RS00255	COG1185	polyribonucleotide nucleotidyltransferase activity
XH83_RS00260	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
XH83_RS00285	COG0625	glutathione transferase activity
XH83_RS00295	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XH83_RS00305	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XH83_RS00325	COG0583	DNA-binding transcription factor activity
XH83_RS00330	COG0667	Aldo Keto reductase
XH83_RS00335	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XH83_RS00360	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XH83_RS00365	COG2226	methyltransferase
XH83_RS00370	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XH83_RS00375	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XH83_RS00380	COG0756	dUTP diphosphatase activity
XH83_RS00385	COG2205	protein histidine kinase activity
XH83_RS00390	COG3178	'Phosphotransferase
XH83_RS00400	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XH83_RS00410	COG1074	ATP-dependent DNA helicase activity
XH83_RS00420	COG1793	dna ligase
XH83_RS00430	COG0285	dihydrofolate synthase activity
XH83_RS00435	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XH83_RS00440	COG0159	tryptophan synthase activity
XH83_RS00445	COG0133	tryptophan synthase activity
XH83_RS00450	COG0135	phosphoribosylanthranilate isomerase activity
XH83_RS00460	COG0776	regulation of translation
XH83_RS00465	COG0616	signal peptide processing
XH83_RS00470	COG0539	negative regulation of cytoplasmic translation
XH83_RS00475	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XH83_RS00480	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XH83_RS00495	COG1846	Transcriptional regulator
XH83_RS00500	COG1764	response to oxidative stress
XH83_RS00520	COG0395	ABC-type sugar transport system, permease component
XH83_RS00525	COG3842	ATPase activity
XH83_RS00530	COG0071	Belongs to the small heat shock protein (HSP20) family
XH83_RS00545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XH83_RS00550	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
XH83_RS00555	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
XH83_RS00560	COG1137	ATPase activity
XH83_RS00565	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XH83_RS00590	COG2814	Major facilitator Superfamily
XH83_RS00595	COG3609	addiction module antidote protein, CC2985 family
XH83_RS00680	COG1968	undecaprenyl-diphosphatase activity
XH83_RS00690	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XH83_RS00710	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XH83_RS00720	COG0291	Belongs to the bacterial ribosomal protein bL35 family
XH83_RS00725	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
XH83_RS00730	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XH83_RS00735	COG2852	Protein conserved in bacteria
XH83_RS00740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XH83_RS00740	COG0072	phenylalanine-tRNA ligase activity
XH83_RS00760	COG1937	Protein conserved in bacteria
XH83_RS00770	COG0864	Transcriptional regulator
XH83_RS00780	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XH83_RS00790	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
XH83_RS00795	COG0588	phosphoglycerate mutase activity
XH83_RS00800	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
XH83_RS00810	COG0284	orotidine-5'-phosphate decarboxylase activity
XH83_RS00820	COG3963	phosphatidate phosphatase activity
XH83_RS00825	COG0484	heat shock protein binding
XH83_RS00830	COG0443	Heat shock 70 kDa protein
XH83_RS00840	COG1335	isochorismatase
XH83_RS00845	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XH83_RS00850	COG1420	regulation of RNA biosynthetic process
XH83_RS00855	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XH83_RS00860	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
XH83_RS00865	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XH83_RS00875	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
XH83_RS00880	COG0792	nuclease activity
XH83_RS00885	COG0189	ligase activity
XH83_RS00895	COG4964	Belongs to the GSP D family
XH83_RS00930	COG5002	protein histidine kinase activity
XH83_RS00930	COG0784	Response regulator, receiver
XH83_RS00930	COG2205	protein histidine kinase activity
XH83_RS00940	COG0628	permease
XH83_RS00950	COG1072	(Pantothenic acid kinase))
XH83_RS00955	COG0140	phosphoribosyl-ATP diphosphatase activity
XH83_RS00960	COG0107	imidazoleglycerol-phosphate synthase activity
XH83_RS00965	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XH83_RS00970	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XH83_RS00980	COG0131	Imidazoleglycerol-phosphate dehydratase
XH83_RS00985	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
XH83_RS01000	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
XH83_RS01015	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
XH83_RS01025	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
XH83_RS01030	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XH83_RS01035	COG0237	dephospho-CoA kinase activity
XH83_RS01040	COG0424	maF-like protein
XH83_RS01045	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
XH83_RS01050	COG1981	membrane
XH83_RS01055	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XH83_RS01060	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
XH83_RS01065	COG0445	tRNA wobble uridine modification
XH83_RS01070	COG0357	Ribosomal RNA small subunit methyltransferase G
XH83_RS01095	COG0495	leucyl-tRNA aminoacylation
XH83_RS01100	COG3706	GGDEF domain
XH83_RS01115	COG2203	Gaf domain
XH83_RS01115	COG4251	negative regulation of phosphorylation
XH83_RS01115	COG3706	GGDEF domain
XH83_RS01115	COG5001	Diguanylate cyclase
XH83_RS01120	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XH83_RS01135	COG0745	RESPONSE REGULATOR receiver
XH83_RS01155	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
XH83_RS01160	COG1674	ftsk spoiiie
XH83_RS01165	COG0436	Aminotransferase
XH83_RS01175	COG0004	ammonium transporteR
XH83_RS01180	COG0347	Belongs to the P(II) protein family
XH83_RS01185	COG0004	ammonium transporteR
XH83_RS01190	COG0347	Belongs to the P(II) protein family
XH83_RS01200	COG1946	Acyl-CoA thioesterase
XH83_RS01205	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XH83_RS01210	COG2835	tetraacyldisaccharide 4'-kinase activity
XH83_RS01250	COG5001	Diguanylate cyclase
XH83_RS01250	COG3300	MHYT domain
XH83_RS01260	COG3118	belongs to the thioredoxin family
XH83_RS01270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XH83_RS01285	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XH83_RS01295	COG0534	Mate efflux family protein
XH83_RS01310	COG2814	Major facilitator Superfamily
XH83_RS01315	COG0405	Gamma-glutamyltransferase
XH83_RS01325	COG0138	bifunctional purine biosynthesis protein purh
XH83_RS01350	COG0175	sulfate reduction
XH83_RS01370	COG1376	ErfK ybiS ycfS ynhG family protein
XH83_RS01375	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XH83_RS01390	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XH83_RS01400	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XH83_RS01405	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XH83_RS01440	COG0726	polysaccharide deacetylase
XH83_RS01455	COG2814	Major facilitator Superfamily
XH83_RS01480	COG4221	oxidoreductase activity
XH83_RS01485	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XH83_RS01490	COG1024	Enoyl-CoA hydratase
XH83_RS01510	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XH83_RS01515	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XH83_RS01520	COG1247	-acetyltransferase
XH83_RS01540	COG3011	Protein conserved in bacteria
XH83_RS01550	COG1217	gtp-binding protein TYPA
XH83_RS01580	COG0784	Response regulator, receiver
XH83_RS01595	COG2154	pterin-4-alpha-carbinolamine dehydratase
XH83_RS01610	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS01620	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XH83_RS01630	COG0671	phosphoesterase, PA-phosphatase related
XH83_RS01635	COG0137	argininosuccinate synthase activity
XH83_RS01665	COG4178	(ABC) transporter
XH83_RS01670	COG4191	Histidine kinase
XH83_RS01670	COG0784	Response regulator, receiver
XH83_RS01695	COG0730	response to heat
XH83_RS01700	COG0318	PFAM AMP-dependent synthetase and ligase
XH83_RS01705	COG4221	oxidoreductase activity
XH83_RS01715	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XH83_RS01720	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
XH83_RS01725	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XH83_RS01735	COG0473	3-isopropylmalate dehydrogenase activity
XH83_RS01755	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XH83_RS01760	COG0288	reversible hydration of carbon dioxide
XH83_RS01765	COG2301	Belongs to the HpcH HpaI aldolase family
XH83_RS01790	COG0066	3-isopropylmalate dehydratase activity
XH83_RS01835	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XH83_RS01840	COG0335	large ribosomal subunit rRNA binding
XH83_RS01845	COG0336	Belongs to the RNA methyltransferase TrmD family
XH83_RS01850	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XH83_RS01855	COG0228	four-way junction DNA binding
XH83_RS01860	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XH83_RS01885	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XH83_RS01890	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XH83_RS01900	COG0564	pseudouridine synthase activity
XH83_RS01905	COG0552	protein localization to endoplasmic reticulum
XH83_RS01910	COG2917	probably involved in intracellular septation
XH83_RS01920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XH83_RS01930	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XH83_RS01935	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XH83_RS01940	COG4133	protoheme IX ABC transporter activity
XH83_RS01945	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
XH83_RS01965	COG0670	Belongs to the BI1 family
XH83_RS01970	COG1136	(ABC) transporter
XH83_RS01970	COG0577	efflux transmembrane transporter activity
XH83_RS01975	COG4181	ATPase activity
XH83_RS01980	COG2755	lipolytic protein G-D-S-L family
XH83_RS01985	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
XH83_RS01990	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XH83_RS01995	COG0039	L-malate dehydrogenase activity
XH83_RS02000	COG0045	succinate-CoA ligase (ADP-forming) activity
XH83_RS02010	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XH83_RS02020	COG0508	dehydrogenase complex catalyzes the overall conversion of
XH83_RS02025	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS02030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XH83_RS02045	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XH83_RS02055	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XH83_RS02060	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XH83_RS02065	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XH83_RS02070	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XH83_RS02075	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XH83_RS02080	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XH83_RS02090	COG0494	nUDIX hydrolase
XH83_RS02095	COG1051	belongs to the nudix hydrolase family
XH83_RS02105	COG0793	Belongs to the peptidase S41A family
XH83_RS02115	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XH83_RS02120	COG0799	negative regulation of ribosome biogenesis
XH83_RS02125	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XH83_RS02130	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XH83_RS02135	COG3609	addiction module antidote protein, CC2985 family
XH83_RS02145	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XH83_RS02160	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XH83_RS02180	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XH83_RS02185	COG0261	This protein binds to 23S rRNA in the presence of protein L20
XH83_RS02220	COG0653	protein targeting
XH83_RS02230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XH83_RS02235	COG0697	spore germination
XH83_RS02240	COG0583	DNA-binding transcription factor activity
XH83_RS02245	COG2249	NAD(P)H dehydrogenase (quinone) activity
XH83_RS02250	COG2203	Gaf domain
XH83_RS02250	COG3706	GGDEF domain
XH83_RS02250	COG4251	negative regulation of phosphorylation
XH83_RS02250	COG5001	Diguanylate cyclase
XH83_RS02290	COG2198	Histidine kinase
XH83_RS02290	COG0784	Response regulator, receiver
XH83_RS02290	COG0643	Histidine kinase
XH83_RS02295	COG0835	chemotaxis
XH83_RS02315	COG2201	protein-glutamate methylesterase activity
XH83_RS02325	COG4566	intracellular signal transduction
XH83_RS02330	COG0784	Response regulator, receiver
XH83_RS02330	COG4191	Histidine kinase
XH83_RS02335	COG4566	intracellular signal transduction
XH83_RS02365	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XH83_RS02380	COG1696	Membrane protein involved in D-alanine export
XH83_RS02390	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XH83_RS02430	COG2706	6-phosphogluconolactonase activity
XH83_RS02440	COG0583	DNA-binding transcription factor activity
XH83_RS02445	COG3842	ATPase activity
XH83_RS02455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XH83_RS02465	COG1176	ABC-type spermidine putrescine transport system, permease component I
XH83_RS02470	COG4208	sulfate ABC transporter
XH83_RS02475	COG5001	Diguanylate cyclase
XH83_RS02510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XH83_RS02545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XH83_RS02560	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
XH83_RS02565	COG0179	Fumarylacetoacetate (FAA) hydrolase
XH83_RS02570	COG3813	Protein conserved in bacteria
XH83_RS02575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH83_RS02620	COG2205	protein histidine kinase activity
XH83_RS02650	COG0477	Major facilitator Superfamily
XH83_RS02655	COG1877	trehalose-phosphatase activity
XH83_RS02660	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
XH83_RS02675	COG0154	amidase activity
XH83_RS02680	COG0300	oxidoreductase activity
XH83_RS02685	COG1309	transcriptional regulator
XH83_RS02700	COG2873	o-acetylhomoserine
XH83_RS02715	COG0514	ATP-dependent DNA helicase (RecQ)
XH83_RS02720	COG2515	1-aminocyclopropane-1-carboxylate deaminase
XH83_RS02725	COG1522	sequence-specific DNA binding
XH83_RS02735	COG3706	GGDEF domain
XH83_RS02750	COG0657	acetylesterase activity
XH83_RS02765	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
XH83_RS02780	COG0697	spore germination
XH83_RS02790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XH83_RS02805	COG2890	protein-(glutamine-N5) methyltransferase activity
XH83_RS02845	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XH83_RS02855	COG0527	aspartate kinase activity
XH83_RS02865	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XH83_RS02885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XH83_RS02895	COG1040	competence protein
XH83_RS02915	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
XH83_RS02920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XH83_RS02925	COG0653	protein targeting
XH83_RS03045	COG3034	peptidoglycan biosynthetic process
XH83_RS03050	COG0825	malonyl-CoA metabolic process
XH83_RS03055	COG4974	Belongs to the 'phage' integrase family
XH83_RS03065	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XH83_RS03070	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XH83_RS03075	COG4536	flavin adenine dinucleotide binding
XH83_RS03090	COG0372	Belongs to the citrate synthase family
XH83_RS03095	COG0372	Belongs to the citrate synthase family
XH83_RS03100	COG0583	DNA-binding transcription factor activity
XH83_RS03105	COG0586	Pfam SNARE associated Golgi protein
XH83_RS03125	COG1902	pentaerythritol trinitrate reductase activity
XH83_RS03165	COG0756	dUTP diphosphatase activity
XH83_RS03175	COG0227	Belongs to the bacterial ribosomal protein bL28 family
XH83_RS03190	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
XH83_RS03195	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XH83_RS03205	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XH83_RS03220	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XH83_RS03225	COG1845	cytochrome c oxidase, subunit III
XH83_RS03230	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XH83_RS03235	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XH83_RS03240	COG0477	Major facilitator Superfamily
XH83_RS03260	COG1024	Enoyl-CoA hydratase
XH83_RS03275	COG1024	Enoyl-CoA hydratase
XH83_RS03280	COG1960	acyl-CoA dehydrogenase activity
XH83_RS03295	COG2261	transglycosylase associated protein
XH83_RS03325	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XH83_RS03350	COG3964	amidohydrolase
XH83_RS03355	COG0747	negative chemotaxis
XH83_RS03360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XH83_RS03380	COG1960	acyl-CoA dehydrogenase activity
XH83_RS03395	COG1024	Enoyl-CoA hydratase
XH83_RS03405	COG0583	DNA-binding transcription factor activity
XH83_RS03410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XH83_RS03465	COG2130	NADP-dependent
XH83_RS03470	COG1301	dicarboxylic acid transport
XH83_RS03475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XH83_RS03495	COG0069	glutamate synthase activity
XH83_RS03505	COG1253	flavin adenine dinucleotide binding
XH83_RS03510	COG0840	transmembrane signaling receptor activity
XH83_RS03515	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
XH83_RS03540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XH83_RS03545	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XH83_RS03560	COG2003	Belongs to the UPF0758 family
XH83_RS03575	COG0024	Methionine aminopeptidase
XH83_RS03580	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
XH83_RS03580	COG3264	Mechanosensitive ion channel
XH83_RS03590	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XH83_RS03595	COG4149	molybdate abc transporter
XH83_RS03600	COG0725	ABC transporter, periplasmic molybdate-binding protein
XH83_RS03605	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
XH83_RS03610	COG5001	Diguanylate cyclase
XH83_RS03620	COG1960	acyl-CoA dehydrogenase activity
XH83_RS03635	COG0154	amidase activity
XH83_RS03655	COG0477	Major facilitator Superfamily
XH83_RS03680	COG0481	GTPase activity
XH83_RS03705	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
XH83_RS03705	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
XH83_RS03710	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XH83_RS03715	COG2205	protein histidine kinase activity
XH83_RS03720	COG0745	RESPONSE REGULATOR receiver
XH83_RS03755	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
XH83_RS03765	COG0058	SHG alpha-glucan phosphorylase activity
XH83_RS03775	COG0583	DNA-binding transcription factor activity
XH83_RS03795	COG0730	response to heat
XH83_RS03815	COG1960	acyl-CoA dehydrogenase activity
XH83_RS03820	COG0183	Belongs to the thiolase family
XH83_RS03825	COG1024	Enoyl-CoA hydratase
XH83_RS03825	COG1250	3-hydroxyacyl-CoA dehydrogenase
XH83_RS03830	COG0625	glutathione transferase activity
XH83_RS03855	COG0681	Belongs to the peptidase S26 family
XH83_RS03860	COG0312	modulator of DNA gyrase
XH83_RS03870	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XH83_RS03875	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XH83_RS03880	COG0109	protoheme IX farnesyltransferase activity
XH83_RS03890	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XH83_RS03905	COG3346	SURF1 family
XH83_RS03930	COG0612	Peptidase, M16
XH83_RS03935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XH83_RS03945	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XH83_RS03950	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XH83_RS03960	COG0356	it plays a direct role in the translocation of protons across the membrane
XH83_RS03975	COG0432	Pfam Uncharacterised protein family UPF0047
XH83_RS03995	COG1764	response to oxidative stress
XH83_RS04000	COG0596	Alpha beta hydrolase
XH83_RS04015	COG2205	protein histidine kinase activity
XH83_RS04015	COG0784	Response regulator, receiver
XH83_RS04015	COG2198	Histidine kinase
XH83_RS04020	COG0156	8-amino-7-oxononanoate synthase activity
XH83_RS04025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XH83_RS04050	COG0640	Transcriptional regulator
XH83_RS04075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH83_RS04085	COG0747	negative chemotaxis
XH83_RS04120	COG2020	methyltransferase activity
XH83_RS04140	COG4585	Histidine kinase
XH83_RS04175	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XH83_RS04220	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XH83_RS04220	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
XH83_RS04245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XH83_RS04250	COG1473	amidohydrolase
XH83_RS04260	COG0601	transmembrane transport
XH83_RS04265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH83_RS04270	COG0444	Belongs to the ABC transporter superfamily
XH83_RS04275	COG4608	Belongs to the ABC transporter superfamily
XH83_RS04280	COG2814	Major facilitator Superfamily
XH83_RS04290	COG3706	GGDEF domain
XH83_RS04290	COG4251	negative regulation of phosphorylation
XH83_RS04290	COG2203	Gaf domain
XH83_RS04290	COG5001	Diguanylate cyclase
XH83_RS04295	COG3360	Dodecin
XH83_RS04345	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XH83_RS04370	COG2086	electron transfer activity
XH83_RS04375	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
XH83_RS04380	COG1250	3-hydroxyacyl-CoA dehydrogenase
XH83_RS04390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XH83_RS04395	COG0165	Argininosuccinate lyase
XH83_RS04405	COG0019	diaminopimelate decarboxylase activity
XH83_RS04415	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XH83_RS04430	COG2204	response regulator
XH83_RS04440	COG2884	Cell division ATP-binding protein ftsE
XH83_RS04470	COG0287	Prephenate dehydrogenase
XH83_RS04475	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XH83_RS04485	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XH83_RS04490	COG2813	Specifically methylates the guanine in position
XH83_RS04490	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XH83_RS04510	COG0542	response to heat
XH83_RS04520	COG0739	heme binding
XH83_RS04560	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
XH83_RS04565	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
XH83_RS04575	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XH83_RS04580	COG5285	phytanoyl-CoA dioxygenase
XH83_RS04590	COG1595	DNA-templated transcription, initiation
XH83_RS04595	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XH83_RS04605	COG2267	carboxylic ester hydrolase activity
XH83_RS04615	COG0318	PFAM AMP-dependent synthetase and ligase
XH83_RS04645	COG1960	acyl-CoA dehydrogenase activity
XH83_RS04650	COG1960	acyl-CoA dehydrogenase activity
XH83_RS04655	COG1960	acyl-CoA dehydrogenase activity
XH83_RS04660	COG0778	Nitroreductase
XH83_RS04675	COG0784	Response regulator, receiver
XH83_RS04690	COG0326	Molecular chaperone. Has ATPase activity
XH83_RS04715	COG0318	PFAM AMP-dependent synthetase and ligase
XH83_RS04765	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XH83_RS04795	COG0803	Belongs to the bacterial solute-binding protein 9 family
XH83_RS04800	COG0523	cobalamin synthesis protein
XH83_RS04810	COG1285	pathogenesis
XH83_RS04830	COG0251	oxidation-reduction process
XH83_RS04860	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
XH83_RS04870	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XH83_RS04880	COG0330	HflC and HflK could
XH83_RS04900	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
XH83_RS04900	COG0517	IMP dehydrogenase activity
XH83_RS04915	COG0067	glutamate synthase
XH83_RS04915	COG0070	glutamate synthase
XH83_RS04915	COG0069	glutamate synthase activity
XH83_RS04930	COG0071	Belongs to the small heat shock protein (HSP20) family
XH83_RS04940	COG2010	Cytochrome c
XH83_RS04950	COG1280	lysine exporter protein (LysE YggA)
XH83_RS04965	COG0583	DNA-binding transcription factor activity
XH83_RS05050	COG0840	transmembrane signaling receptor activity
XH83_RS05065	COG2205	protein histidine kinase activity
XH83_RS05070	COG0745	RESPONSE REGULATOR receiver
XH83_RS05080	COG1472	Belongs to the glycosyl hydrolase 3 family
XH83_RS05085	COG0583	DNA-binding transcription factor activity
XH83_RS05090	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XH83_RS05120	COG1012	belongs to the aldehyde dehydrogenase family
XH83_RS05125	COG1902	pentaerythritol trinitrate reductase activity
XH83_RS05150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XH83_RS05165	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
XH83_RS05170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XH83_RS05185	COG0765	amino acid transport
XH83_RS05190	COG0765	amino acid transport
XH83_RS05195	COG1126	abc transporter atp-binding protein
XH83_RS05205	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XH83_RS05220	COG0583	DNA-binding transcription factor activity
XH83_RS05250	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
XH83_RS05260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XH83_RS05265	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
XH83_RS05290	COG1215	transferase activity, transferring glycosyl groups
XH83_RS05310	COG0655	NAD(P)H dehydrogenase (quinone) activity
XH83_RS05315	COG1741	Belongs to the pirin family
XH83_RS05325	COG0583	DNA-binding transcription factor activity
XH83_RS05350	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XH83_RS05365	COG0789	Transcriptional regulator
XH83_RS05370	COG1733	regulation of RNA biosynthetic process
XH83_RS05375	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS05385	COG0257	Belongs to the bacterial ribosomal protein bL36 family
XH83_RS05410	COG3474	cytochrome
XH83_RS05415	COG0277	FAD linked oxidase domain protein
XH83_RS05420	COG0277	FAD linked oxidase domain protein
XH83_RS05425	COG0247	lactate metabolic process
XH83_RS05440	COG4178	(ABC) transporter
XH83_RS05445	COG1620	l-lactate permease
XH83_RS05460	COG0459	protein refolding
XH83_RS05465	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XH83_RS05480	COG1376	ErfK ybiS ycfS ynhG family protein
XH83_RS05480	COG1388	LysM domain
XH83_RS05485	COG3416	Protein conserved in bacteria
XH83_RS05495	COG0463	Glycosyl transferase, family 2
XH83_RS05500	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XH83_RS05505	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
XH83_RS05530	COG0312	modulator of DNA gyrase
XH83_RS05550	COG1519	Transferase
XH83_RS05555	COG1663	tetraacyldisaccharide 4'-kinase activity
XH83_RS05585	COG1570	exodeoxyribonuclease VII activity
XH83_RS05620	COG0194	GDP metabolic process
XH83_RS05630	COG0151	Belongs to the GarS family
XH83_RS05635	COG0596	Alpha beta hydrolase
XH83_RS05640	COG0590	tRNA wobble adenosine to inosine editing
XH83_RS05645	COG1187	pseudouridine synthase activity
XH83_RS05650	COG0742	ribosomal rna small subunit methyltransferase
XH83_RS05655	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XH83_RS05695	COG0612	Peptidase, M16
XH83_RS05700	COG0612	Peptidase, M16
XH83_RS05710	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XH83_RS05715	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
XH83_RS05720	COG0196	riboflavin kinase activity
XH83_RS05725	COG0745	RESPONSE REGULATOR receiver
XH83_RS05735	COG2200	EAL domain
XH83_RS05735	COG2771	luxR family
XH83_RS05740	COG1295	ribonuclease BN
XH83_RS05750	COG2890	protein-(glutamine-N5) methyltransferase activity
XH83_RS05755	COG0314	molybdopterin synthase activity
XH83_RS05765	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XH83_RS05770	COG0322	excinuclease ABC activity
XH83_RS05775	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
XH83_RS05780	COG1278	Cold shock
XH83_RS05785	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XH83_RS05815	COG0745	RESPONSE REGULATOR receiver
XH83_RS05820	COG1846	Transcriptional regulator
XH83_RS05825	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XH83_RS05835	COG0124	histidyl-tRNA synthetase
XH83_RS05840	COG1942	4-Oxalocrotonate Tautomerase
XH83_RS05855	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
XH83_RS05865	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XH83_RS05870	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XH83_RS05880	COG1496	oxidoreductase activity
XH83_RS05890	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XH83_RS05905	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XH83_RS05910	COG0193	aminoacyl-tRNA hydrolase activity
XH83_RS05915	COG0012	GTP binding
XH83_RS05925	COG2030	dehydratase
XH83_RS05980	COG0556	nucleotide-excision repair
XH83_RS05995	COG0583	DNA-binding transcription factor activity
XH83_RS06040	COG0667	Aldo Keto reductase
XH83_RS06065	COG0625	glutathione transferase activity
XH83_RS06070	COG0436	Aminotransferase
XH83_RS06080	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XH83_RS06095	COG0659	secondary active sulfate transmembrane transporter activity
XH83_RS06100	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XH83_RS06110	COG1304	FMN binding
XH83_RS06120	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XH83_RS06125	COG2223	nitrite transmembrane transporter activity
XH83_RS06140	COG0625	glutathione transferase activity
XH83_RS06160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XH83_RS06165	COG0183	Belongs to the thiolase family
XH83_RS06170	COG0840	transmembrane signaling receptor activity
XH83_RS06175	COG2205	protein histidine kinase activity
XH83_RS06200	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
XH83_RS06225	COG2301	Belongs to the HpcH HpaI aldolase family
XH83_RS06255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XH83_RS06260	COG0583	DNA-binding transcription factor activity
XH83_RS06265	COG0492	ferredoxin-NADP+ reductase activity
XH83_RS06270	COG1522	sequence-specific DNA binding
XH83_RS06275	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XH83_RS06280	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XH83_RS06285	COG2814	Major facilitator Superfamily
XH83_RS06315	COG0505	Belongs to the CarA family
XH83_RS06330	COG0596	Alpha beta hydrolase
XH83_RS06335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XH83_RS06340	COG1846	Transcriptional regulator
XH83_RS06375	COG0640	Transcriptional regulator
XH83_RS06385	COG1280	lysine exporter protein (LysE YggA)
XH83_RS06410	COG0358	DNA primase activity
XH83_RS06415	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XH83_RS06465	COG1280	lysine exporter protein (LysE YggA)
XH83_RS06470	COG3706	GGDEF domain
XH83_RS06485	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XH83_RS06490	COG0564	pseudouridine synthase activity
XH83_RS06505	COG4585	Histidine kinase
XH83_RS06525	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XH83_RS06555	COG0840	transmembrane signaling receptor activity
XH83_RS06565	COG0318	PFAM AMP-dependent synthetase and ligase
XH83_RS06570	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
XH83_RS06575	COG3284	Transcriptional regulator
XH83_RS06585	COG1902	pentaerythritol trinitrate reductase activity
XH83_RS06605	COG3734	2-keto-3-deoxy-galactonokinase
XH83_RS06610	COG0800	Aldolase
XH83_RS06615	COG0028	Belongs to the TPP enzyme family
XH83_RS06655	COG2205	protein histidine kinase activity
XH83_RS06665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XH83_RS06670	COG2514	catechol 2,3-dioxygenase activity
XH83_RS06675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XH83_RS06685	COG1960	acyl-CoA dehydrogenase activity
XH83_RS06690	COG1960	acyl-CoA dehydrogenase activity
XH83_RS06695	COG1024	Enoyl-CoA hydratase
XH83_RS06700	COG1704	LemA family
XH83_RS06705	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
XH83_RS06730	COG0625	glutathione transferase activity
XH83_RS06740	COG0506	proline dehydrogenase activity
XH83_RS06740	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
XH83_RS06740	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
XH83_RS06750	COG1278	Cold shock
XH83_RS06775	COG3768	UPF0283 membrane protein
XH83_RS06780	COG3106	COG3106 Predicted ATPase
XH83_RS06785	COG1272	protein, Hemolysin III
XH83_RS06790	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS06800	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS06810	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
XH83_RS06820	COG1960	acyl-CoA dehydrogenase activity
XH83_RS06825	COG0583	DNA-binding transcription factor activity
XH83_RS06845	COG0501	Belongs to the peptidase M48B family
XH83_RS06860	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
XH83_RS06875	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
XH83_RS06880	COG2226	methyltransferase
XH83_RS06890	COG1376	ErfK ybiS ycfS ynhG family protein
XH83_RS06895	COG0028	Belongs to the TPP enzyme family
XH83_RS06920	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XH83_RS06930	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS06970	COG0643	Histidine kinase
XH83_RS06970	COG0784	Response regulator, receiver
XH83_RS06970	COG2198	Histidine kinase
XH83_RS06975	COG0835	chemotaxis
XH83_RS06980	COG0784	Response regulator, receiver
XH83_RS06980	COG0643	Histidine kinase
XH83_RS06980	COG2198	Histidine kinase
XH83_RS06985	COG2201	protein-glutamate methylesterase activity
XH83_RS07000	COG0754	glutathionylspermidine amidase activity
XH83_RS07010	COG3766	membrane
XH83_RS07030	COG1595	DNA-templated transcription, initiation
XH83_RS07050	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XH83_RS07095	COG1309	transcriptional regulator
XH83_RS07100	COG2080	2 iron, 2 sulfur cluster binding
XH83_RS07105	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XH83_RS07110	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XH83_RS07130	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XH83_RS07135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XH83_RS07145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XH83_RS07150	COG0765	amino acid transport
XH83_RS07155	COG1126	abc transporter atp-binding protein
XH83_RS07160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XH83_RS07170	COG0405	Gamma-glutamyltransferase
XH83_RS07175	COG1024	Enoyl-CoA hydratase
XH83_RS07230	COG2226	methyltransferase
XH83_RS07270	COG3220	belongs to the UPF0276 family
XH83_RS07280	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XH83_RS07295	COG1309	transcriptional regulator
XH83_RS07310	COG0697	spore germination
XH83_RS07325	COG3300	MHYT domain
XH83_RS07325	COG5001	Diguanylate cyclase
XH83_RS07340	COG1129	ABC transporter
XH83_RS07350	COG1172	Belongs to the binding-protein-dependent transport system permease family
XH83_RS07355	COG1879	ABC-type sugar transport system periplasmic component
XH83_RS07360	COG1172	Belongs to the binding-protein-dependent transport system permease family
XH83_RS07375	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XH83_RS07390	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
XH83_RS07455	COG0303	'Molybdopterin
XH83_RS07465	COG0746	molybdenum cofactor guanylyltransferase activity
XH83_RS07475	COG1763	Mo-molybdopterin cofactor biosynthetic process
XH83_RS07490	COG2223	nitrite transmembrane transporter activity
XH83_RS07500	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XH83_RS07505	COG3383	formate dehydrogenase (NAD+) activity
XH83_RS07520	COG0431	NADPH-dependent FMN reductase
XH83_RS07520	COG1053	succinate dehydrogenase
XH83_RS07520	COG3976	FMN-binding domain protein
XH83_RS07550	COG5001	Diguanylate cyclase
XH83_RS07550	COG3447	MASE1 domain protein
XH83_RS07550	COG5002	protein histidine kinase activity
XH83_RS07555	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
XH83_RS07560	COG0583	DNA-binding transcription factor activity
XH83_RS07565	COG3485	protocatechuate 3,4-dioxygenase
XH83_RS07570	COG3485	protocatechuate 3,4-dioxygenase
XH83_RS07605	COG0745	RESPONSE REGULATOR receiver
XH83_RS07610	COG2198	Histidine kinase
XH83_RS07610	COG0643	Histidine kinase
XH83_RS07615	COG0835	chemotaxis
XH83_RS07620	COG0840	transmembrane signaling receptor activity
XH83_RS07625	COG0840	transmembrane signaling receptor activity
XH83_RS07635	COG0840	transmembrane signaling receptor activity
XH83_RS07645	COG2201	protein-glutamate methylesterase activity
XH83_RS07675	COG2771	luxR family
XH83_RS07675	COG2200	EAL domain
XH83_RS07750	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XH83_RS07795	COG3206	protein involved in exopolysaccharide biosynthesis
XH83_RS07795	COG0489	protein tyrosine kinase activity
XH83_RS07840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XH83_RS07845	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
XH83_RS07855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XH83_RS07980	COG2345	Transcriptional regulator
XH83_RS07990	COG0745	RESPONSE REGULATOR receiver
XH83_RS08010	COG1278	Cold shock
XH83_RS08060	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XH83_RS08065	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
XH83_RS08075	COG3206	protein involved in exopolysaccharide biosynthesis
XH83_RS08075	COG0489	protein tyrosine kinase activity
XH83_RS08100	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XH83_RS08210	COG5001	Diguanylate cyclase
XH83_RS08210	COG3300	MHYT domain
XH83_RS08235	COG0181	hydroxymethylbilane synthase activity
XH83_RS08240	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XH83_RS08250	COG4251	negative regulation of phosphorylation
XH83_RS08250	COG3706	GGDEF domain
XH83_RS08250	COG2203	Gaf domain
XH83_RS08250	COG5001	Diguanylate cyclase
XH83_RS08255	COG2900	Belongs to the SlyX family
XH83_RS08260	COG1054	Belongs to the UPF0176 family
XH83_RS08265	COG0405	Gamma-glutamyltransferase
XH83_RS08270	COG2080	2 iron, 2 sulfur cluster binding
XH83_RS08275	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XH83_RS08280	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XH83_RS08290	COG3237	CsbD-like
XH83_RS08325	COG4191	Histidine kinase
XH83_RS08325	COG0784	Response regulator, receiver
XH83_RS08340	COG3214	Protein conserved in bacteria
XH83_RS08365	COG1309	transcriptional regulator
XH83_RS08385	COG1024	Enoyl-CoA hydratase
XH83_RS08385	COG1250	3-hydroxyacyl-CoA dehydrogenase
XH83_RS08395	COG1607	acyl-coa hydrolase
XH83_RS08415	COG1349	DNA-binding transcription factor activity
XH83_RS08435	COG3842	ATPase activity
XH83_RS08440	COG3842	ATPase activity
XH83_RS08450	COG0395	ABC-type sugar transport system, permease component
XH83_RS08465	COG1902	pentaerythritol trinitrate reductase activity
XH83_RS08490	COG0501	Belongs to the peptidase M48B family
XH83_RS08540	COG0494	nUDIX hydrolase
XH83_RS08550	COG0463	Glycosyl transferase, family 2
XH83_RS08560	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
XH83_RS08570	COG4771	TonB-dependent receptor
XH83_RS08595	COG0714	Associated with various cellular activities
XH83_RS08615	COG0617	tRNA 3'-terminal CCA addition
XH83_RS08660	COG0408	coproporphyrinogen oxidase activity
XH83_RS08665	COG0602	queuosine metabolic process
XH83_RS08670	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XH83_RS08675	COG0723	plastoquinol--plastocyanin reductase activity
XH83_RS08680	COG2857	Cytochrome c1
XH83_RS08680	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XH83_RS08700	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XH83_RS08725	COG1704	LemA family
XH83_RS08735	COG1196	nuclear chromosome segregation
XH83_RS08740	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XH83_RS08760	COG1194	a g-specific adenine glycosylase
XH83_RS08775	COG0625	glutathione transferase activity
XH83_RS08800	COG4251	negative regulation of phosphorylation
XH83_RS08810	COG0625	glutathione transferase activity
XH83_RS08820	COG2189	Belongs to the N(4) N(6)-methyltransferase family
XH83_RS08825	COG2321	neutral zinc metallopeptidase
XH83_RS08830	COG0521	Mo-molybdopterin cofactor biosynthetic process
XH83_RS08835	COG1846	Transcriptional regulator
XH83_RS08835	COG0456	acetyltransferase
XH83_RS08855	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
XH83_RS08870	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
XH83_RS08880	COG1573	uracil-dna glycosylase
XH83_RS08895	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
XH83_RS08905	COG1280	lysine exporter protein (LysE YggA)
XH83_RS08910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XH83_RS08920	COG0142	geranyltranstransferase activity
XH83_RS08930	COG2813	Specifically methylates the guanine in position
XH83_RS08945	COG0752	glycyl-tRNA synthetase alpha subunit
XH83_RS08950	COG0751	glycine-tRNA ligase activity
XH83_RS08965	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XH83_RS08965	COG0574	Belongs to the PEP-utilizing enzyme family
XH83_RS08980	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
XH83_RS08985	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
XH83_RS08995	COG0604	alcohol dehydrogenase
XH83_RS09035	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
XH83_RS09040	COG0519	Catalyzes the synthesis of GMP from XMP
XH83_RS09045	COG0354	folic acid binding
XH83_RS09050	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XH83_RS09055	COG2897	thiosulfate sulfurtransferase activity
XH83_RS09060	COG1595	DNA-templated transcription, initiation
XH83_RS09095	COG2135	peptidase activity
XH83_RS09115	COG0456	acetyltransferase
XH83_RS09115	COG0454	-acetyltransferase
XH83_RS09120	COG0277	FAD linked oxidase domain protein
XH83_RS09125	COG0009	L-threonylcarbamoyladenylate synthase
XH83_RS09145	COG0583	DNA-binding transcription factor activity
XH83_RS09150	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XH83_RS09200	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XH83_RS09220	COG1850	ribulose-bisphosphate carboxylase activity
XH83_RS09225	COG4451	ribulose bisphosphate carboxylase, small
XH83_RS09245	COG3300	MHYT domain
XH83_RS09245	COG5001	Diguanylate cyclase
XH83_RS09345	COG0653	protein targeting
XH83_RS09360	COG0671	phosphoesterase, PA-phosphatase related
XH83_RS09365	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS09380	COG0028	Belongs to the TPP enzyme family
XH83_RS09400	COG2814	Major facilitator Superfamily
XH83_RS09420	COG0656	L-ascorbic acid biosynthetic process
XH83_RS09440	COG3384	dioxygenase
XH83_RS09445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XH83_RS09465	COG1960	acyl-CoA dehydrogenase activity
XH83_RS09505	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS09510	COG0259	pyridoxamine-phosphate oxidase activity
XH83_RS09535	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XH83_RS09545	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XH83_RS09555	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
XH83_RS09560	COG1993	acr, cog1993
XH83_RS09565	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XH83_RS09570	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XH83_RS09590	COG1024	Enoyl-CoA hydratase
XH83_RS09620	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH83_RS09635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XH83_RS09640	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XH83_RS09645	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
XH83_RS09655	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XH83_RS09660	COG1722	exodeoxyribonuclease VII activity
XH83_RS09665	COG0123	including yeast histone deacetylase and acetoin utilization protein
XH83_RS09670	COG0737	Belongs to the 5'-nucleotidase family
XH83_RS09670	COG4085	toxin activity
XH83_RS09670	COG1525	nuclease
XH83_RS09690	COG1960	acyl-CoA dehydrogenase activity
XH83_RS09725	COG0318	PFAM AMP-dependent synthetase and ligase
XH83_RS09735	COG1960	acyl-CoA dehydrogenase activity
XH83_RS09740	COG1960	acyl-CoA dehydrogenase activity
XH83_RS09745	COG0183	Belongs to the thiolase family
XH83_RS09755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XH83_RS09765	COG0183	Belongs to the thiolase family
XH83_RS09775	COG0243	molybdopterin cofactor binding
XH83_RS09785	COG1024	Enoyl-CoA hydratase
XH83_RS09810	COG0318	PFAM AMP-dependent synthetase and ligase
XH83_RS09820	COG1902	pentaerythritol trinitrate reductase activity
XH83_RS09830	COG3795	YCII-related domain
XH83_RS09835	COG4941	Belongs to the sigma-70 factor family
XH83_RS09860	COG0179	Fumarylacetoacetate (FAA) hydrolase
XH83_RS09875	COG1522	sequence-specific DNA binding
XH83_RS09880	COG1846	Transcriptional regulator
XH83_RS09885	COG0346	lactoylglutathione lyase activity
XH83_RS09890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XH83_RS09905	COG2217	Heavy metal translocating P-type atpase
XH83_RS09905	COG2608	mercury ion transmembrane transporter activity
XH83_RS09920	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH83_RS09935	COG1473	amidohydrolase
XH83_RS09940	COG4948	Mandelate Racemase Muconate Lactonizing
XH83_RS09985	COG3181	Tripartite tricarboxylate transporter family receptor
XH83_RS09995	COG0741	lytic transglycosylase activity
XH83_RS10000	COG1376	ErfK ybiS ycfS ynhG family protein
XH83_RS10030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XH83_RS10040	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XH83_RS10060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XH83_RS10065	COG1053	succinate dehydrogenase
XH83_RS10085	COG1335	isochorismatase
XH83_RS10095	COG3258	Cytochrome c
XH83_RS10115	COG0446	pyridine nucleotide-disulphide oxidoreductase
XH83_RS10130	COG1032	radical SAM domain protein
XH83_RS10135	COG2814	Major facilitator Superfamily
XH83_RS10140	COG0473	3-isopropylmalate dehydrogenase activity
XH83_RS10185	COG4106	trans-aconitate 2-methyltransferase activity
XH83_RS10200	COG2015	COG2015, Alkyl sulfatase and related hydrolases
XH83_RS10205	COG0438	transferase activity, transferring glycosyl groups
XH83_RS10210	COG1132	(ABC) transporter
XH83_RS10230	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XH83_RS10235	COG0745	RESPONSE REGULATOR receiver
XH83_RS10240	COG4566	intracellular signal transduction
XH83_RS10245	COG4191	Histidine kinase
XH83_RS10255	COG0516	GMP reductase activity
XH83_RS10255	COG0517	IMP dehydrogenase activity
XH83_RS10260	COG3278	Belongs to the heme-copper respiratory oxidase family
XH83_RS10275	COG2010	Cytochrome c
XH83_RS10290	COG2217	Heavy metal translocating P-type atpase
XH83_RS10320	COG0583	DNA-binding transcription factor activity
XH83_RS10325	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS10340	COG0297	glycogen (starch) synthase activity
XH83_RS10350	COG0747	negative chemotaxis
XH83_RS10360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH83_RS10365	COG0444	Belongs to the ABC transporter superfamily
XH83_RS10380	COG0473	3-isopropylmalate dehydrogenase activity
XH83_RS10390	COG1024	Enoyl-CoA hydratase
XH83_RS10395	COG1396	sequence-specific DNA binding
XH83_RS10410	COG0785	Cytochrome C biogenesis protein
XH83_RS10425	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
XH83_RS10425	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
XH83_RS10440	COG3485	protocatechuate 3,4-dioxygenase
XH83_RS10450	COG0702	epimerase
XH83_RS10455	COG2815	serine threonine protein kinase
XH83_RS10455	COG0515	serine threonine protein kinase
XH83_RS10465	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XH83_RS10475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XH83_RS10475	COG1116	anion transmembrane transporter activity
XH83_RS10480	COG2223	nitrite transmembrane transporter activity
XH83_RS10485	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XH83_RS10485	COG1017	nitric oxide dioxygenase activity
XH83_RS10490	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XH83_RS10495	COG0243	molybdopterin cofactor binding
XH83_RS10505	COG0656	L-ascorbic acid biosynthetic process
XH83_RS10510	COG0697	spore germination
XH83_RS10515	COG1063	alcohol dehydrogenase
XH83_RS10520	COG1522	sequence-specific DNA binding
XH83_RS10525	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
XH83_RS10535	COG3386	PFAM SMP-30 Gluconolaconase
XH83_RS10540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XH83_RS10545	COG2020	methyltransferase activity
XH83_RS10565	COG3710	Transcriptional regulator
XH83_RS10565	COG0457	Tetratricopeptide repeat
XH83_RS10580	COG0129	dihydroxy-acid dehydratase activity
XH83_RS10610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XH83_RS10615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XH83_RS10625	COG1309	transcriptional regulator
XH83_RS10630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XH83_RS10650	COG0673	inositol 2-dehydrogenase activity
XH83_RS10665	COG2124	cytochrome p450
XH83_RS10675	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
XH83_RS10675	COG0028	Belongs to the TPP enzyme family
XH83_RS10685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XH83_RS10690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XH83_RS10700	COG2204	response regulator
XH83_RS10715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH83_RS10720	COG0601	transmembrane transport
XH83_RS10730	COG4608	Belongs to the ABC transporter superfamily
XH83_RS10735	COG0444	Belongs to the ABC transporter superfamily
XH83_RS10750	COG4608	Belongs to the ABC transporter superfamily
XH83_RS10755	COG0444	Belongs to the ABC transporter superfamily
XH83_RS10760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH83_RS10770	COG0747	negative chemotaxis
XH83_RS10795	COG2124	cytochrome p450
XH83_RS10795	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XH83_RS10805	COG0596	Alpha beta hydrolase
XH83_RS10820	COG0456	acetyltransferase
XH83_RS10820	COG0454	-acetyltransferase
XH83_RS10835	COG2733	membrane
XH83_RS10840	COG0596	Alpha beta hydrolase
XH83_RS10845	COG3327	negative regulation of DNA-templated transcription, initiation
XH83_RS10850	COG3396	Phenylacetate-CoA oxygenase
XH83_RS10855	COG3460	Phenylacetate-CoA oxygenase
XH83_RS10860	COG3396	Phenylacetate-CoA oxygenase
XH83_RS10865	COG2151	metal-sulfur cluster biosynthetic enzyme
XH83_RS10870	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XH83_RS10875	COG2050	protein possibly involved in aromatic compounds catabolism
XH83_RS10910	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XH83_RS10915	COG0477	Major facilitator Superfamily
XH83_RS10940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XH83_RS10945	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XH83_RS10955	COG4597	amino acid ABC transporter
XH83_RS10960	COG0765	amino acid transport
XH83_RS10970	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS10975	COG0473	3-isopropylmalate dehydrogenase activity
XH83_RS10985	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
XH83_RS10990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XH83_RS11000	COG0583	DNA-binding transcription factor activity
XH83_RS11005	COG4336	lyase activity
XH83_RS11020	COG1079	Belongs to the binding-protein-dependent transport system permease family
XH83_RS11035	COG0235	Class ii aldolase
XH83_RS11040	COG2084	Dehydrogenase
XH83_RS11045	COG3622	Belongs to the hyi family
XH83_RS11050	COG3395	kinase activity
XH83_RS11055	COG0840	transmembrane signaling receptor activity
XH83_RS11060	COG0840	transmembrane signaling receptor activity
XH83_RS11070	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XH83_RS11075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XH83_RS11085	COG2070	2-Nitropropane dioxygenase
XH83_RS11090	COG0625	glutathione transferase activity
XH83_RS11100	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XH83_RS11115	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS11120	COG1024	Enoyl-CoA hydratase
XH83_RS11135	COG1024	Enoyl-CoA hydratase
XH83_RS11140	COG1960	acyl-CoA dehydrogenase activity
XH83_RS11155	COG1024	Enoyl-CoA hydratase
XH83_RS11165	COG1024	Enoyl-CoA hydratase
XH83_RS11195	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XH83_RS11200	COG3386	PFAM SMP-30 Gluconolaconase
XH83_RS11205	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS11235	COG3145	DNA-N1-methyladenine dioxygenase activity
XH83_RS11255	COG3971	2-oxopent-4-enoate hydratase activity
XH83_RS11260	COG1846	Transcriptional regulator
XH83_RS11270	COG2721	sulfolactate sulfo-lyase activity
XH83_RS11310	COG0302	gtp cyclohydrolase
XH83_RS11335	COG0596	Alpha beta hydrolase
XH83_RS11360	COG0840	transmembrane signaling receptor activity
XH83_RS11365	COG4303	Ethanolamine ammonia lyase large subunit
XH83_RS11375	COG4302	ethanolamine ammonia-lyase activity
XH83_RS11400	COG1562	ergosterol biosynthetic process
XH83_RS11405	COG1562	ergosterol biosynthetic process
XH83_RS11410	COG1233	COG1233 Phytoene dehydrogenase and related
XH83_RS11415	COG1657	PFAM Prenyltransferase squalene oxidase
XH83_RS11420	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
XH83_RS11430	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XH83_RS11460	COG1595	DNA-templated transcription, initiation
XH83_RS11485	COG1473	amidohydrolase
XH83_RS11490	COG0306	phosphate transporter
XH83_RS11495	COG1573	uracil-dna glycosylase
XH83_RS11515	COG0587	DNA-directed DNA polymerase activity
XH83_RS11520	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS11530	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH83_RS11545	COG3618	amidohydrolase
XH83_RS11550	COG0563	adenylate kinase activity
XH83_RS11570	COG1024	Enoyl-CoA hydratase
XH83_RS11630	COG1703	isobutyryl-CoA mutase activity
XH83_RS11675	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XH83_RS11680	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XH83_RS11685	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XH83_RS11700	COG0433	COG0433 Predicted ATPase
XH83_RS11725	COG4957	zinc ion binding
XH83_RS11730	COG2166	iron-sulfur cluster assembly
XH83_RS11740	COG2205	protein histidine kinase activity
XH83_RS11800	COG0179	Fumarylacetoacetate (FAA) hydrolase
XH83_RS11805	COG1802	Transcriptional regulator
XH83_RS11840	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XH83_RS11855	COG0798	PFAM Bile acid sodium symporter
XH83_RS11900	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XH83_RS11900	COG1672	PFAM Archaeal ATPase
XH83_RS11930	COG2983	Belongs to the UPF0260 family
XH83_RS11935	COG0477	Major facilitator Superfamily
XH83_RS11940	COG4191	Histidine kinase
XH83_RS11940	COG0784	Response regulator, receiver
XH83_RS11945	COG0028	Belongs to the TPP enzyme family
XH83_RS11960	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XH83_RS11965	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XH83_RS11970	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
XH83_RS11985	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
XH83_RS12015	COG4235	cytochrome complex assembly
XH83_RS12020	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XH83_RS12025	COG1138	Cytochrome C-type biogenesis protein
XH83_RS12030	COG3088	subunit of a heme lyase
XH83_RS12045	COG0745	RESPONSE REGULATOR receiver
XH83_RS12050	COG2205	protein histidine kinase activity
XH83_RS12055	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XH83_RS12065	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XH83_RS12070	COG3383	formate dehydrogenase (NAD+) activity
XH83_RS12085	COG0583	DNA-binding transcription factor activity
XH83_RS12090	COG2205	protein histidine kinase activity
XH83_RS12090	COG2202	Pas domain
XH83_RS12095	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
XH83_RS12100	COG0604	alcohol dehydrogenase
XH83_RS12100	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS12100	COG3321	synthase
XH83_RS12125	COG0179	Fumarylacetoacetate (FAA) hydrolase
XH83_RS12130	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XH83_RS12155	COG0443	Heat shock 70 kDa protein
XH83_RS12170	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH83_RS12180	COG1802	Transcriptional regulator
XH83_RS12215	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
XH83_RS12220	COG3960	tartronate-semialdehyde synthase activity
XH83_RS12225	COG3622	Belongs to the hyi family
XH83_RS12230	COG2084	Dehydrogenase
XH83_RS12255	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XH83_RS12270	COG1522	sequence-specific DNA binding
XH83_RS12275	COG0686	Belongs to the AlaDH PNT family
XH83_RS12280	COG2072	flavoprotein involved in K transport
XH83_RS12285	COG1309	transcriptional regulator
XH83_RS12315	COG0410	ABC transporter
XH83_RS12325	COG2855	membrane
XH83_RS12330	COG1116	anion transmembrane transporter activity
XH83_RS12335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XH83_RS12340	COG4521	taurine ABC transporter
XH83_RS12345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XH83_RS12360	COG1053	succinate dehydrogenase
XH83_RS12380	COG1879	ABC-type sugar transport system periplasmic component
XH83_RS12385	COG1129	ABC transporter
XH83_RS12390	COG1172	Belongs to the binding-protein-dependent transport system permease family
XH83_RS12395	COG1172	Belongs to the binding-protein-dependent transport system permease family
XH83_RS12415	COG3386	PFAM SMP-30 Gluconolaconase
XH83_RS12420	COG4213	ABC transporter substrate-binding protein
XH83_RS12430	COG4214	carbohydrate transport
XH83_RS12440	COG1845	cytochrome c oxidase, subunit III
XH83_RS12455	COG3256	nitric oxide reductase
XH83_RS12460	COG0714	Associated with various cellular activities
XH83_RS12470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XH83_RS12500	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS12520	COG0154	amidase activity
XH83_RS12530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH83_RS12535	COG0444	Belongs to the ABC transporter superfamily
XH83_RS12540	COG4608	Belongs to the ABC transporter superfamily
XH83_RS12545	COG0747	negative chemotaxis
XH83_RS12560	COG1376	ErfK ybiS ycfS ynhG family protein
XH83_RS12565	COG0400	carboxylic ester hydrolase activity
XH83_RS12570	COG0346	lactoylglutathione lyase activity
XH83_RS12575	COG0583	DNA-binding transcription factor activity
XH83_RS12615	COG0778	Nitroreductase
XH83_RS12620	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
XH83_RS12630	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XH83_RS12640	COG1492	cobalamin metabolic process
XH83_RS12685	COG2099	Precorrin-6x reductase
XH83_RS12700	COG2875	Belongs to the precorrin methyltransferase family
XH83_RS12705	COG1797	cobyrinic acid a,c-diamide synthase activity
XH83_RS12710	COG1648	precorrin-2 dehydrogenase activity
XH83_RS12710	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XH83_RS12725	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XH83_RS12745	COG0747	negative chemotaxis
XH83_RS12750	COG0601	transmembrane transport
XH83_RS12755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH83_RS12760	COG0444	Belongs to the ABC transporter superfamily
XH83_RS12765	COG4608	Belongs to the ABC transporter superfamily
XH83_RS12775	COG1879	ABC-type sugar transport system periplasmic component
XH83_RS12780	COG1172	Belongs to the binding-protein-dependent transport system permease family
XH83_RS12785	COG1172	Belongs to the binding-protein-dependent transport system permease family
XH83_RS12790	COG1129	ABC transporter
XH83_RS12795	COG0277	FAD linked oxidase domain protein
XH83_RS12800	COG3485	protocatechuate 3,4-dioxygenase
XH83_RS12810	COG0402	S-adenosylhomocysteine deaminase activity
XH83_RS12830	COG1070	Carbohydrate kinase
XH83_RS12840	COG1172	Belongs to the binding-protein-dependent transport system permease family
XH83_RS12845	COG1879	ABC-type sugar transport system periplasmic component
XH83_RS12870	COG0445	tRNA wobble uridine modification
XH83_RS12880	COG3181	Tripartite tricarboxylate transporter family receptor
XH83_RS12890	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
XH83_RS12920	COG2814	Major facilitator Superfamily
XH83_RS12940	COG0348	domain, Protein
XH83_RS12940	COG3901	Regulator of nitric oxide reductase transcription
XH83_RS12945	COG2010	Cytochrome c
XH83_RS12950	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XH83_RS12980	COG0535	radical SAM domain protein
XH83_RS13100	COG4792	protein secretion
XH83_RS13105	COG4791	protein targeting
XH83_RS13110	COG4794	Type iii secretion
XH83_RS13115	COG4790	Type iii secretion
XH83_RS13120	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
XH83_RS13170	COG1450	Type ii and iii secretion system protein
XH83_RS13195	COG4789	Type iii secretion
XH83_RS13235	COG0583	DNA-binding transcription factor activity
XH83_RS13240	COG1301	dicarboxylic acid transport
XH83_RS13245	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
XH83_RS13250	COG3257	ureidoglycine aminohydrolase activity
XH83_RS13265	COG2202	Pas domain
XH83_RS13265	COG2205	protein histidine kinase activity
XH83_RS13270	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
XH83_RS13275	COG2084	Dehydrogenase
XH83_RS13290	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
XH83_RS13295	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
XH83_RS13315	COG0745	RESPONSE REGULATOR receiver
XH83_RS13330	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
XH83_RS13340	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XH83_RS13350	COG0546	phosphoglycolate phosphatase activity
XH83_RS13355	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
XH83_RS13385	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
XH83_RS13410	COG0861	Integral membrane protein TerC family
XH83_RS13430	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XH83_RS13435	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XH83_RS13455	COG0215	cysteine-tRNA ligase activity
XH83_RS13465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XH83_RS13475	COG0583	DNA-binding transcription factor activity
XH83_RS13480	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XH83_RS13490	COG5265	(ABC) transporter
XH83_RS13495	COG0688	phosphatidylethanolamine metabolic process
XH83_RS13500	COG1183	phosphatidylcholine synthase activity
XH83_RS13515	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XH83_RS13525	COG3158	transport of potassium into the cell
XH83_RS13530	COG3158	transport of potassium into the cell
XH83_RS13540	COG0436	Aminotransferase
XH83_RS13545	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
XH83_RS13555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XH83_RS13565	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XH83_RS13570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XH83_RS13615	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
XH83_RS13620	COG1285	pathogenesis
XH83_RS13635	COG2010	Cytochrome c
XH83_RS13635	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XH83_RS13640	COG2080	2 iron, 2 sulfur cluster binding
XH83_RS13680	COG1846	Transcriptional regulator
XH83_RS13705	COG2124	cytochrome p450
XH83_RS13760	COG1301	dicarboxylic acid transport
XH83_RS13765	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
XH83_RS13790	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XH83_RS13810	COG0318	PFAM AMP-dependent synthetase and ligase
XH83_RS13815	COG2072	flavoprotein involved in K transport
XH83_RS13820	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XH83_RS13895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XH83_RS13900	COG1309	transcriptional regulator
XH83_RS13905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XH83_RS13915	COG2814	Major facilitator Superfamily
XH83_RS13920	COG0402	S-adenosylhomocysteine deaminase activity
XH83_RS13930	COG1234	tRNA 3'-trailer cleavage
XH83_RS13940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XH83_RS13945	COG0277	FAD linked oxidase domain protein
XH83_RS13950	COG3395	kinase activity
XH83_RS13955	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XH83_RS13960	COG1454	alcohol dehydrogenase
XH83_RS13975	COG5507	3-demethylubiquinone-9 3-methyltransferase
XH83_RS13995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XH83_RS14000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XH83_RS14010	COG4774	siderophore transport
XH83_RS14015	COG3128	pkhd-type hydroxylase
XH83_RS14025	COG0848	biopolymer transport protein
XH83_RS14040	COG1994	Peptidase M50
XH83_RS14050	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS14055	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS14060	COG0129	dihydroxy-acid dehydratase activity
XH83_RS14065	COG1609	Transcriptional regulator
XH83_RS14070	COG3842	ATPase activity
XH83_RS14085	COG0395	ABC-type sugar transport system, permease component
XH83_RS14090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XH83_RS14095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XH83_RS14100	COG0800	Aldolase
XH83_RS14105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XH83_RS14120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XH83_RS14140	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
XH83_RS14140	COG2066	Belongs to the glutaminase family
XH83_RS14155	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
XH83_RS14165	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XH83_RS14175	COG0277	FAD linked oxidase domain protein
XH83_RS14210	COG2271	Major facilitator Superfamily
XH83_RS14215	COG0183	Belongs to the thiolase family
XH83_RS14220	COG1024	Enoyl-CoA hydratase
XH83_RS14270	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS14275	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
XH83_RS14275	COG0493	'glutamate synthase
XH83_RS14280	COG2814	Major facilitator Superfamily
XH83_RS14295	COG0488	(ABC) transporter
XH83_RS14300	COG1671	Belongs to the UPF0178 family
XH83_RS14320	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XH83_RS14335	COG2130	NADP-dependent
XH83_RS14360	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XH83_RS14360	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XH83_RS14380	COG1090	epimerase
XH83_RS14385	COG0583	DNA-binding transcription factor activity
XH83_RS14400	COG0321	lipoyl(octanoyl) transferase activity
XH83_RS14445	COG0492	ferredoxin-NADP+ reductase activity
XH83_RS14475	COG2239	Acts as a magnesium transporter
XH83_RS14485	COG0656	L-ascorbic acid biosynthetic process
XH83_RS14520	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XH83_RS14525	COG1192	Involved in chromosome partitioning
XH83_RS14545	COG1686	Belongs to the peptidase S11 family
XH83_RS14560	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
XH83_RS14575	COG2814	Major facilitator Superfamily
XH83_RS14585	COG0667	Aldo Keto reductase
XH83_RS14600	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XH83_RS14635	COG1720	tRNA m6t6A37 methyltransferase activity
XH83_RS14640	COG0537	adenosine 5'-monophosphoramidase activity
XH83_RS14675	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XH83_RS14685	COG0784	Response regulator, receiver
XH83_RS14695	COG2207	Transcriptional regulator
XH83_RS14730	COG0267	Belongs to the bacterial ribosomal protein bL33 family
XH83_RS14750	COG0557	exoribonuclease II activity
XH83_RS14755	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XH83_RS14765	COG0655	NAD(P)H dehydrogenase (quinone) activity
XH83_RS14775	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS14785	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XH83_RS14790	COG1733	regulation of RNA biosynthetic process
XH83_RS14795	COG0758	DNA mediated transformation
XH83_RS14800	COG0154	amidase activity
XH83_RS14810	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
XH83_RS14815	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XH83_RS14820	COG0540	Belongs to the ATCase OTCase family
XH83_RS14825	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XH83_RS14830	COG1960	acyl-CoA dehydrogenase activity
XH83_RS14845	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XH83_RS14855	COG0583	DNA-binding transcription factor activity
XH83_RS14860	COG2070	2-Nitropropane dioxygenase
XH83_RS14865	COG2070	2-Nitropropane dioxygenase
XH83_RS14870	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
XH83_RS14880	COG0154	amidase activity
XH83_RS14895	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
XH83_RS14920	COG0741	lytic transglycosylase activity
XH83_RS14925	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XH83_RS14930	COG1970	mechanosensitive ion channel activity
XH83_RS14935	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XH83_RS14955	COG1758	RNA polymerase activity
XH83_RS14965	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XH83_RS14970	COG0736	holo-[acyl-carrier-protein] synthase activity
XH83_RS14975	COG0681	Belongs to the peptidase S26 family
XH83_RS14980	COG0571	ribonuclease III activity
XH83_RS14985	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XH83_RS14995	COG1381	Involved in DNA repair and RecF pathway recombination
XH83_RS15005	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
XH83_RS15035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XH83_RS15060	COG1914	H( )-stimulated, divalent metal cation uptake system
XH83_RS15085	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
XH83_RS15095	COG0113	porphobilinogen synthase activity
XH83_RS15120	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XH83_RS15125	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XH83_RS15130	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XH83_RS15130	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XH83_RS15140	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XH83_RS15145	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XH83_RS15150	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XH83_RS15155	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XH83_RS15165	COG0789	Transcriptional regulator
XH83_RS15215	COG0416	fatty acid biosynthetic process
XH83_RS15220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XH83_RS15225	COG0776	regulation of translation
XH83_RS15390	COG0657	acetylesterase activity
XH83_RS15445	COG3268	Saccharopine dehydrogenase
XH83_RS15450	COG3268	Saccharopine dehydrogenase
XH83_RS15455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XH83_RS15460	COG1846	Transcriptional regulator
XH83_RS15475	COG0438	transferase activity, transferring glycosyl groups
XH83_RS15500	COG1612	heme a metabolic process
XH83_RS15520	COG1024	Enoyl-CoA hydratase
XH83_RS15530	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
XH83_RS15535	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XH83_RS15565	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XH83_RS15590	COG0252	asparaginase activity
XH83_RS15595	COG0174	glutamine synthetase
XH83_RS15600	COG0347	Belongs to the P(II) protein family
XH83_RS15605	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XH83_RS15605	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XH83_RS15620	COG0544	peptidyl-prolyl cis-trans isomerase activity
XH83_RS15625	COG0740	serine-type endopeptidase activity
XH83_RS15630	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XH83_RS15635	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
XH83_RS15660	COG2226	methyltransferase
XH83_RS15665	COG1230	cation diffusion facilitator family transporter
XH83_RS15700	COG2195	Cleaves the N-terminal amino acid of tripeptides
XH83_RS15720	COG2814	Major facilitator Superfamily
XH83_RS15735	COG4774	siderophore transport
XH83_RS15745	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XH83_RS15755	COG0649	NAD binding
XH83_RS15765	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XH83_RS15775	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XH83_RS15785	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XH83_RS15790	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XH83_RS15800	COG0713	ATP synthesis coupled electron transport
XH83_RS15815	COG1007	ATP synthesis coupled electron transport
XH83_RS15820	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
XH83_RS15820	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
XH83_RS15830	COG0346	lactoylglutathione lyase activity
XH83_RS15850	COG0747	negative chemotaxis
XH83_RS15855	COG0601	transmembrane transport
XH83_RS15860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH83_RS15865	COG0444	Belongs to the ABC transporter superfamily
XH83_RS15870	COG4608	Belongs to the ABC transporter superfamily
XH83_RS15880	COG1172	Belongs to the binding-protein-dependent transport system permease family
XH83_RS15885	COG1129	ABC transporter
XH83_RS15905	COG4774	siderophore transport
XH83_RS15935	COG0442	prolyl-tRNA aminoacylation
XH83_RS15945	COG1136	(ABC) transporter
XH83_RS15970	COG0024	Methionine aminopeptidase
XH83_RS15980	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XH83_RS16025	COG0052	Belongs to the universal ribosomal protein uS2 family
XH83_RS16030	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XH83_RS16035	COG0528	UMP kinase activity
XH83_RS16040	COG0233	cytoplasmic translational termination
XH83_RS16045	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XH83_RS16055	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XH83_RS16060	COG0750	zinc metalloprotease
XH83_RS16065	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XH83_RS16070	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XH83_RS16075	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XH83_RS16085	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XH83_RS16095	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XH83_RS16115	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS16125	COG0395	ABC-type sugar transport system, permease component
XH83_RS16130	COG1175	transmembrane transport
XH83_RS16145	COG0372	Belongs to the citrate synthase family
XH83_RS16150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XH83_RS16155	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XH83_RS16180	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XH83_RS16185	COG0303	'Molybdopterin
XH83_RS16195	COG1011	Hydrolase
XH83_RS16200	COG1304	FMN binding
XH83_RS16205	COG0793	Belongs to the peptidase S41A family
XH83_RS16210	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
XH83_RS16215	COG5001	Diguanylate cyclase
XH83_RS16215	COG3300	MHYT domain
XH83_RS16240	COG0315	cyclic pyranopterin monophosphate synthase activity
XH83_RS16245	COG0134	indole-3-glycerol-phosphate synthase activity
XH83_RS16250	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XH83_RS16255	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XH83_RS16260	COG0149	triose-phosphate isomerase activity
XH83_RS16270	COG0504	CTP synthase activity
XH83_RS16275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XH83_RS16280	COG2205	protein histidine kinase activity
XH83_RS16285	COG0745	RESPONSE REGULATOR receiver
XH83_RS16295	COG2877	3-deoxy-8-phosphooctulonate synthase activity
XH83_RS16310	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XH83_RS16320	COG0148	phosphopyruvate hydratase activity
XH83_RS16335	COG0431	NADPH-dependent FMN reductase
XH83_RS16350	COG1012	belongs to the aldehyde dehydrogenase family
XH83_RS16355	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XH83_RS16360	COG0022	dehydrogenase e1 component
XH83_RS16360	COG0508	dehydrogenase complex catalyzes the overall conversion of
XH83_RS16370	COG0590	tRNA wobble adenosine to inosine editing
XH83_RS16375	COG0508	dehydrogenase complex catalyzes the overall conversion of
XH83_RS16385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XH83_RS16390	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
XH83_RS16405	COG4566	intracellular signal transduction
XH83_RS16410	COG4566	intracellular signal transduction
XH83_RS16415	COG4191	Histidine kinase
XH83_RS16455	COG0179	Fumarylacetoacetate (FAA) hydrolase
XH83_RS16465	COG4206	TonB-dependent receptor
XH83_RS16475	COG0129	dihydroxy-acid dehydratase activity
XH83_RS16480	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
XH83_RS16485	COG0708	Exodeoxyribonuclease III
XH83_RS16490	COG2198	Histidine kinase
XH83_RS16490	COG5002	protein histidine kinase activity
XH83_RS16490	COG0784	Response regulator, receiver
XH83_RS16500	COG0232	Belongs to the dGTPase family. Type 2 subfamily
XH83_RS16505	COG0018	arginyl-trna synthetase
XH83_RS16515	COG1472	Belongs to the glycosyl hydrolase 3 family
XH83_RS16520	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XH83_RS16525	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XH83_RS16530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XH83_RS16535	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XH83_RS16540	COG0805	protein transport
XH83_RS16545	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XH83_RS16555	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XH83_RS16565	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XH83_RS16580	COG1862	Preprotein translocase
XH83_RS16585	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XH83_RS16605	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XH83_RS16610	COG1104	cysteine desulfurase activity
XH83_RS16620	COG2340	Cysteine-rich secretory protein family
XH83_RS16630	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
XH83_RS16715	COG0546	phosphoglycolate phosphatase activity
XH83_RS16725	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XH83_RS16735	COG0629	single-stranded DNA binding
XH83_RS16740	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
XH83_RS16745	COG3158	transport of potassium into the cell
XH83_RS16755	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XH83_RS16785	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XH83_RS16790	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XH83_RS16800	COG1309	transcriptional regulator
XH83_RS16810	COG0343	queuine tRNA-ribosyltransferase activity
XH83_RS16855	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XH83_RS16890	COG0628	permease
XH83_RS16915	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XH83_RS16980	COG1285	pathogenesis
XH83_RS16990	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XH83_RS17005	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XH83_RS17025	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XH83_RS17035	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
XH83_RS17040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XH83_RS17070	COG0679	Auxin Efflux Carrier
XH83_RS17075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XH83_RS17080	COG1183	phosphatidylcholine synthase activity
XH83_RS17085	COG1253	flavin adenine dinucleotide binding
XH83_RS17095	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XH83_RS17105	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XH83_RS17110	COG3707	response regulator
XH83_RS17115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XH83_RS17120	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XH83_RS17125	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XH83_RS17135	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
XH83_RS17140	COG1984	allophanate hydrolase subunit 2
XH83_RS17145	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
XH83_RS17150	COG0473	3-isopropylmalate dehydrogenase activity
XH83_RS17150	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XH83_RS17215	COG1175	transmembrane transport
XH83_RS17250	COG1335	isochorismatase
XH83_RS17260	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XH83_RS17260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XH83_RS17285	COG0444	Belongs to the ABC transporter superfamily
XH83_RS17295	COG0601	transmembrane transport
XH83_RS17300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH83_RS17305	COG0129	dihydroxy-acid dehydratase activity
XH83_RS17325	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XH83_RS17330	COG4566	intracellular signal transduction
XH83_RS17350	COG2985	domain, Protein
XH83_RS17370	COG2985	domain, Protein
XH83_RS17405	COG3064	Membrane
XH83_RS17425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XH83_RS17460	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XH83_RS17465	COG2267	carboxylic ester hydrolase activity
XH83_RS17470	COG1686	Belongs to the peptidase S11 family
XH83_RS17475	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XH83_RS17490	COG0084	hydrolase, TatD family'
XH83_RS17495	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
XH83_RS17495	COG0321	lipoyl(octanoyl) transferase activity
XH83_RS17520	COG0318	PFAM AMP-dependent synthetase and ligase
XH83_RS17525	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
XH83_RS17530	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XH83_RS17550	COG4263	nitrous-oxide reductase activity
XH83_RS17590	COG4774	siderophore transport
XH83_RS17610	COG2011	ABC-type metal ion transport system permease component
XH83_RS17615	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XH83_RS17620	COG0471	metal ion transport
XH83_RS17625	COG1024	Enoyl-CoA hydratase
XH83_RS17650	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
XH83_RS17655	COG3956	TIGRFAM MazG family protein
XH83_RS17660	COG0454	-acetyltransferase
XH83_RS17665	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XH83_RS17670	COG1923	regulation of RNA biosynthetic process
XH83_RS17675	COG2204	response regulator
XH83_RS17680	COG5000	phosphorelay sensor kinase activity
XH83_RS17705	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XH83_RS17705	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
XH83_RS17710	COG1058	Belongs to the CinA family
XH83_RS17710	COG1546	Belongs to the CinA family
XH83_RS17715	COG0668	transmembrane transport
XH83_RS17720	COG2863	cytochrome
XH83_RS17740	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XH83_RS17745	COG2863	cytochrome
XH83_RS17750	COG2867	negative regulation of translational initiation
XH83_RS17755	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XH83_RS17760	COG2094	Belongs to the DNA glycosylase MPG family
XH83_RS17765	COG0525	valine-tRNA ligase activity
XH83_RS17780	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XH83_RS17800	COG2268	Band 7 protein
XH83_RS17845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XH83_RS17880	COG1126	abc transporter atp-binding protein
XH83_RS17885	COG0765	amino acid transport
XH83_RS17890	COG4597	amino acid ABC transporter
XH83_RS17895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XH83_RS17900	COG0626	cystathionine gamma-synthase activity
XH83_RS17905	COG1283	sodium-dependent phosphate transmembrane transporter activity
XH83_RS17915	COG0463	Glycosyl transferase, family 2
XH83_RS17920	COG0671	phosphoesterase, PA-phosphatase related
XH83_RS17930	COG4953	penicillin-binding protein 1C
XH83_RS17935	COG2373	Large extracellular alpha-helical protein
XH83_RS18010	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XH83_RS18035	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
XH83_RS18035	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
XH83_RS18040	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XH83_RS18045	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XH83_RS18055	COG4770	biotin carboxylase activity
XH83_RS18060	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XH83_RS18065	COG1960	acyl-CoA dehydrogenase activity
XH83_RS18080	COG1522	sequence-specific DNA binding
XH83_RS18120	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XH83_RS18165	COG0776	regulation of translation
XH83_RS18220	COG0702	epimerase
XH83_RS18285	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XH83_RS18305	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XH83_RS18315	COG2354	Protein conserved in bacteria
XH83_RS18325	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XH83_RS18355	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS18360	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XH83_RS18365	COG0840	transmembrane signaling receptor activity
XH83_RS18375	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XH83_RS18395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH83_RS18400	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
XH83_RS18405	COG1802	Transcriptional regulator
XH83_RS18410	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XH83_RS18420	COG0583	DNA-binding transcription factor activity
XH83_RS18430	COG1494	fructose-1,6-bisphosphatase
XH83_RS18440	COG0436	Aminotransferase
XH83_RS18450	COG3243	poly(R)-hydroxyalkanoic acid synthase
XH83_RS18460	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
XH83_RS18475	COG0586	Pfam SNARE associated Golgi protein
XH83_RS18480	COG0187	DNA topoisomerase II activity
XH83_RS18495	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS18510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XH83_RS18530	COG0513	Belongs to the DEAD box helicase family
XH83_RS18545	COG0316	Belongs to the HesB IscA family
XH83_RS18550	COG2151	metal-sulfur cluster biosynthetic enzyme
XH83_RS18555	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XH83_RS18560	COG0719	Fe-S assembly protein
XH83_RS18565	COG0396	ATPase activity
XH83_RS18570	COG0719	Fe-S assembly protein
XH83_RS18575	COG1104	cysteine desulfurase activity
XH83_RS18590	COG2945	thiolester hydrolase activity
XH83_RS18600	COG0625	glutathione transferase activity
XH83_RS18605	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
XH83_RS18610	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XH83_RS18620	COG2259	Doxx family
XH83_RS18635	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XH83_RS18640	COG0739	heme binding
XH83_RS18660	COG0438	transferase activity, transferring glycosyl groups
XH83_RS18690	COG2084	Dehydrogenase
XH83_RS18700	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XH83_RS18710	COG1530	ribonuclease E activity
XH83_RS18710	COG1530	ribonuclease E activity
XH83_RS18715	COG0154	amidase activity
XH83_RS18720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XH83_RS18725	COG1301	dicarboxylic acid transport
XH83_RS18730	COG1268	BioY protein
XH83_RS18735	COG0436	Aminotransferase
XH83_RS18755	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XH83_RS18760	COG0511	ligase activity, forming carbon-carbon bonds
XH83_RS18765	COG0439	Biotin carboxylase
XH83_RS18770	COG5002	protein histidine kinase activity
XH83_RS18775	COG0784	Response regulator, receiver
XH83_RS18780	COG4565	transcriptional regulatory protein
XH83_RS18785	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
XH83_RS18795	COG0657	acetylesterase activity
XH83_RS18830	COG0784	Response regulator, receiver
XH83_RS18830	COG4191	Histidine kinase
XH83_RS18835	COG0697	spore germination
XH83_RS18840	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XH83_RS18865	COG0693	protein deglycase activity
XH83_RS18930	COG2824	Alkylphosphonate utilization operon protein PhnA
XH83_RS18970	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XH83_RS18990	COG1309	transcriptional regulator
XH83_RS19030	COG1376	ErfK ybiS ycfS ynhG family protein
XH83_RS19045	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS19065	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XH83_RS19070	COG2894	cell division
XH83_RS19075	COG0850	regulation of cytokinetic process
XH83_RS19085	COG1309	transcriptional regulator
XH83_RS19090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XH83_RS19115	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
XH83_RS19145	COG2207	Transcriptional regulator
XH83_RS19165	COG0840	transmembrane signaling receptor activity
XH83_RS19170	COG0778	Nitroreductase
XH83_RS19175	COG0657	acetylesterase activity
XH83_RS19200	COG0488	(ABC) transporter
XH83_RS19210	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XH83_RS19215	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
XH83_RS19220	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
XH83_RS19225	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XH83_RS19280	COG0174	glutamine synthetase
XH83_RS19295	COG2365	Tyrosine phosphatase family
XH83_RS19300	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS19330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
XH83_RS19340	COG3483	tryptophan 2,3-dioxygenase activity
XH83_RS19350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XH83_RS19385	COG3045	CreA protein
XH83_RS19395	COG0386	Belongs to the glutathione peroxidase family
XH83_RS19415	COG0280	phosphate acetyltransferase
XH83_RS19415	COG0281	malic enzyme
XH83_RS19425	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XH83_RS19430	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
XH83_RS19435	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
XH83_RS19440	COG1175	transmembrane transport
XH83_RS19450	COG1653	transport
XH83_RS19470	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
XH83_RS19475	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XH83_RS19510	COG1278	Cold shock
XH83_RS19515	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XH83_RS19520	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XH83_RS19525	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XH83_RS19535	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XH83_RS19540	COG0248	Ppx GppA phosphatase
XH83_RS19585	COG0861	Integral membrane protein TerC family
XH83_RS19590	COG0105	UTP biosynthetic process
XH83_RS19610	COG0488	(ABC) transporter
XH83_RS19620	COG3493	citrate carrier protein
XH83_RS19625	COG0066	3-isopropylmalate dehydratase activity
XH83_RS19630	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XH83_RS19650	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XH83_RS19655	COG0795	lipopolysaccharide-transporting ATPase activity
XH83_RS19665	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XH83_RS19675	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XH83_RS19680	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XH83_RS19740	COG0194	GDP metabolic process
XH83_RS19745	COG1561	YicC-like family, N-terminal region
XH83_RS19750	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XH83_RS19755	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XH83_RS19760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XH83_RS19770	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XH83_RS19785	COG0360	Binds together with S18 to 16S ribosomal RNA
XH83_RS19790	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
XH83_RS19800	COG0359	binds to the 23S rRNA
XH83_RS19820	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XH83_RS19825	COG0305	Participates in initiation and elongation during chromosome replication
XH83_RS19830	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XH83_RS19840	COG0708	Exodeoxyribonuclease III
XH83_RS19855	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XH83_RS19860	COG0297	glycogen (starch) synthase activity
XH83_RS19885	COG1879	ABC-type sugar transport system periplasmic component
XH83_RS19895	COG1286	toxin biosynthetic process
XH83_RS19900	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
XH83_RS19905	COG0300	oxidoreductase activity
XH83_RS19925	COG1160	GTP binding
XH83_RS19940	COG0318	PFAM AMP-dependent synthetase and ligase
XH83_RS19965	COG0306	phosphate transporter
XH83_RS19970	COG1392	Phosphate transport regulator
XH83_RS20005	COG1393	Belongs to the ArsC family
XH83_RS20010	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XH83_RS20010	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XH83_RS20015	COG1309	transcriptional regulator
XH83_RS20025	COG0625	glutathione transferase activity
XH83_RS20050	COG1690	Belongs to the RtcB family
XH83_RS20090	COG0583	DNA-binding transcription factor activity
XH83_RS20095	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS20120	COG0714	Associated with various cellular activities
XH83_RS20130	COG3552	Protein containing von Willebrand factor type A (VWA) domain
XH83_RS20170	COG0242	peptide deformylase activity
XH83_RS20210	COG1175	transmembrane transport
XH83_RS20215	COG1653	transport
XH83_RS20220	COG3842	ATPase activity
XH83_RS20235	COG1175	transmembrane transport
XH83_RS20240	COG0395	ABC-type sugar transport system, permease component
XH83_RS20245	COG3842	ATPase activity
XH83_RS20250	COG2188	Transcriptional regulator
XH83_RS20260	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XH83_RS20270	COG2188	Transcriptional regulator
XH83_RS20305	COG2197	response regulator
XH83_RS20340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XH83_RS20345	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
XH83_RS20370	COG0463	Glycosyl transferase, family 2
XH83_RS20385	COG0438	transferase activity, transferring glycosyl groups
XH83_RS20390	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XH83_RS20395	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XH83_RS20400	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XH83_RS20410	COG2244	polysaccharide biosynthetic process
XH83_RS20420	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XH83_RS20425	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
XH83_RS20450	COG2274	protein secretion by the type I secretion system
XH83_RS20470	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
XH83_RS20475	COG1091	dTDP-4-dehydrorhamnose reductase activity
XH83_RS20480	COG1088	dTDP-glucose 4,6-dehydratase activity
XH83_RS20485	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
XH83_RS20490	COG3206	protein involved in exopolysaccharide biosynthesis
XH83_RS20490	COG0489	protein tyrosine kinase activity
XH83_RS20580	COG1595	DNA-templated transcription, initiation
XH83_RS20595	COG1024	Enoyl-CoA hydratase
XH83_RS20630	COG0071	Belongs to the small heat shock protein (HSP20) family
XH83_RS20635	COG0071	Belongs to the small heat shock protein (HSP20) family
XH83_RS20645	COG4191	Histidine kinase
XH83_RS20645	COG0784	Response regulator, receiver
XH83_RS20650	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XH83_RS20655	COG2095	MarC family integral membrane protein
XH83_RS20670	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XH83_RS20675	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XH83_RS20685	COG0071	Belongs to the small heat shock protein (HSP20) family
XH83_RS20695	COG0459	protein refolding
XH83_RS20700	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XH83_RS20710	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XH83_RS20715	COG2249	NAD(P)H dehydrogenase (quinone) activity
XH83_RS20720	COG0583	DNA-binding transcription factor activity
XH83_RS20735	COG0071	Belongs to the small heat shock protein (HSP20) family
XH83_RS20750	COG0405	Gamma-glutamyltransferase
XH83_RS20755	COG0154	amidase activity
XH83_RS20760	COG4211	Belongs to the binding-protein-dependent transport system permease family
XH83_RS20775	COG1137	ATPase activity
XH83_RS20785	COG0523	cobalamin synthesis protein
XH83_RS20795	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS20805	COG1012	belongs to the aldehyde dehydrogenase family
XH83_RS20810	COG5441	Belongs to the UPF0261 family
XH83_RS20820	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XH83_RS20840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XH83_RS20845	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS20850	COG3836	Belongs to the HpcH HpaI aldolase family
XH83_RS20855	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS20875	COG0436	Aminotransferase
XH83_RS20910	COG2050	protein possibly involved in aromatic compounds catabolism
XH83_RS20915	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH83_RS20920	COG0546	phosphoglycolate phosphatase activity
XH83_RS20930	COG2814	Major facilitator Superfamily
XH83_RS20940	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS20950	COG1024	Enoyl-CoA hydratase
XH83_RS20960	COG0318	PFAM AMP-dependent synthetase and ligase
XH83_RS20970	COG1309	transcriptional regulator
XH83_RS20975	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH83_RS20985	COG1024	Enoyl-CoA hydratase
XH83_RS21025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XH83_RS21025	COG0519	Catalyzes the synthesis of GMP from XMP
XH83_RS21040	COG1278	Cold shock
XH83_RS21045	COG1254	Belongs to the acylphosphatase family
XH83_RS21050	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
XH83_RS21055	COG4770	biotin carboxylase activity
XH83_RS21075	COG0471	metal ion transport
XH83_RS21075	COG3273	potassium ion transport
XH83_RS21085	COG2271	Major facilitator Superfamily
XH83_RS21095	COG4948	Mandelate Racemase Muconate Lactonizing
XH83_RS21100	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS21105	COG1063	alcohol dehydrogenase
XH83_RS21120	COG2197	response regulator
XH83_RS21125	COG1234	tRNA 3'-trailer cleavage
XH83_RS21135	COG1414	Transcriptional regulator
XH83_RS21140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XH83_RS21145	COG0179	Fumarylacetoacetate (FAA) hydrolase
XH83_RS21165	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH83_RS21205	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS21250	COG4566	intracellular signal transduction
XH83_RS21255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XH83_RS21260	COG0577	efflux transmembrane transporter activity
XH83_RS21260	COG1136	(ABC) transporter
XH83_RS21265	COG1136	(ABC) transporter
XH83_RS21265	COG0577	efflux transmembrane transporter activity
XH83_RS21270	COG2197	response regulator
XH83_RS21285	COG0450	alkyl hydroperoxide reductase
XH83_RS21295	COG0415	Belongs to the DNA photolyase family
XH83_RS21390	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS21395	COG2030	dehydratase
XH83_RS21420	COG2860	membrane
XH83_RS21465	COG0625	glutathione transferase activity
XH83_RS21485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XH83_RS21510	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XH83_RS21535	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XH83_RS21540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XH83_RS21545	COG1733	regulation of RNA biosynthetic process
XH83_RS21565	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS21570	COG3181	Tripartite tricarboxylate transporter family receptor
XH83_RS21575	COG0203	ribosomal protein L17
XH83_RS21580	COG0202	RNA polymerase activity
XH83_RS21585	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
XH83_RS21590	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
XH83_RS21595	COG0563	adenylate kinase activity
XH83_RS21600	COG0201	protein transport
XH83_RS21605	COG0201	protein transport
XH83_RS21610	COG0200	Binds to the 23S rRNA
XH83_RS21615	COG1841	ribosomal large subunit assembly
XH83_RS21620	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
XH83_RS21625	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
XH83_RS21630	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
XH83_RS21635	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
XH83_RS21640	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
XH83_RS21645	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XH83_RS21650	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XH83_RS21655	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
XH83_RS21660	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XH83_RS21665	COG0255	Belongs to the universal ribosomal protein uL29 family
XH83_RS21670	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XH83_RS21675	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
XH83_RS21680	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
XH83_RS21685	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
XH83_RS21690	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XH83_RS21695	COG0089	rRNA binding
XH83_RS21700	COG0088	Forms part of the polypeptide exit tunnel
XH83_RS21705	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
XH83_RS21710	COG0051	transcription antitermination factor activity, RNA binding
XH83_RS21715	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XH83_RS21720	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XH83_RS21725	COG0049	tRNA binding
XH83_RS21730	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XH83_RS21735	COG1132	(ABC) transporter
XH83_RS21740	COG1231	oxidoreductase activity
XH83_RS21745	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XH83_RS21750	COG0085	RNA polymerase activity
XH83_RS21760	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XH83_RS21765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XH83_RS21770	COG0081	regulation of translation
XH83_RS21775	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XH83_RS21780	COG0250	Participates in transcription elongation, termination and antitermination
XH83_RS21785	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XH83_RS21805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XH83_RS21810	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
XH83_RS21810	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
XH83_RS21815	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XH83_RS21830	COG3959	Transketolase, thiamine diphosphate binding domain
XH83_RS21835	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XH83_RS21860	COG2226	methyltransferase
XH83_RS21885	COG0673	inositol 2-dehydrogenase activity
XH83_RS21920	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS21925	COG0406	alpha-ribazole phosphatase activity
XH83_RS21950	COG1960	acyl-CoA dehydrogenase activity
XH83_RS21955	COG1309	transcriptional regulator
XH83_RS21980	COG3246	L-lysine catabolic process to acetate
XH83_RS22055	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS22060	COG2084	Dehydrogenase
XH83_RS22065	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XH83_RS22075	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS22100	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
XH83_RS22120	COG3386	PFAM SMP-30 Gluconolaconase
XH83_RS22125	COG0667	Aldo Keto reductase
XH83_RS22145	COG1073	alpha beta
XH83_RS22155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XH83_RS22170	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH83_RS22185	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XH83_RS22205	COG1024	Enoyl-CoA hydratase
XH83_RS22210	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XH83_RS22215	COG0288	reversible hydration of carbon dioxide
XH83_RS22220	COG1960	acyl-CoA dehydrogenase activity
XH83_RS22225	COG2814	Major facilitator Superfamily
XH83_RS22230	COG0318	PFAM AMP-dependent synthetase and ligase
XH83_RS22235	COG0318	PFAM AMP-dependent synthetase and ligase
XH83_RS22290	COG0583	DNA-binding transcription factor activity
XH83_RS22330	COG3451	type IV secretory pathway VirB4
XH83_RS22340	COG3838	Conjugal transfer protein Trbc
XH83_RS22345	COG4962	Type ii secretion system protein e
XH83_RS22370	COG1196	nuclear chromosome segregation
XH83_RS22370	COG0741	lytic transglycosylase activity
XH83_RS22370	COG0739	heme binding
XH83_RS22375	COG0681	Belongs to the peptidase S26 family
XH83_RS22405	COG1476	TRANSCRIPTIONal
XH83_RS22410	COG5489	Protein of unknown function (DUF736)
XH83_RS22455	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
XH83_RS22490	COG5002	protein histidine kinase activity
XH83_RS22545	COG4191	Histidine kinase
XH83_RS22545	COG0784	Response regulator, receiver
XH83_RS22565	COG3795	YCII-related domain
XH83_RS22575	COG0210	DNA helicase
XH83_RS22585	COG0402	S-adenosylhomocysteine deaminase activity
XH83_RS22595	COG0477	Major facilitator Superfamily
XH83_RS22615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XH83_RS22705	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XH83_RS22730	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XH83_RS22735	COG0302	gtp cyclohydrolase
XH83_RS22750	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
XH83_RS22765	COG0531	amino acid
XH83_RS22785	COG2814	Major facilitator Superfamily
XH83_RS22790	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XH83_RS22815	COG5001	Diguanylate cyclase
XH83_RS22825	COG0604	alcohol dehydrogenase
XH83_RS22825	COG3321	synthase
XH83_RS22825	COG4221	oxidoreductase activity
XH83_RS22825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XH83_RS22840	COG1752	Esterase of the alpha-beta hydrolase superfamily
XH83_RS22845	COG0517	IMP dehydrogenase activity
XH83_RS22880	COG0513	Belongs to the DEAD box helicase family
XH83_RS22905	COG1063	alcohol dehydrogenase
XH83_RS22925	COG1917	Cupin 2, conserved barrel domain protein
XH83_RS22925	COG4977	sequence-specific DNA binding
XH83_RS22940	COG3842	ATPase activity
XH83_RS22950	COG1176	ABC-type spermidine putrescine transport system, permease component I
XH83_RS22955	COG3833	ABC-type maltose transport systems, permease component
XH83_RS22965	COG3546	catalase activity
XH83_RS23025	COG4191	Histidine kinase
XH83_RS23040	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XH83_RS23055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XH83_RS23090	COG0747	negative chemotaxis
XH83_RS23095	COG0747	negative chemotaxis
XH83_RS23105	COG0601	transmembrane transport
XH83_RS23110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH83_RS23115	COG4172	Belongs to the ABC transporter superfamily
XH83_RS23125	COG1473	amidohydrolase
XH83_RS23130	COG0154	amidase activity
XH83_RS23135	COG1024	Enoyl-CoA hydratase
XH83_RS23140	COG3321	synthase
XH83_RS23140	COG0604	alcohol dehydrogenase
XH83_RS23150	COG0625	glutathione transferase activity
XH83_RS23165	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
XH83_RS23170	COG1058	Belongs to the CinA family
XH83_RS23170	COG1546	Belongs to the CinA family
XH83_RS23175	COG2308	Evidence 4 Homologs of previously reported genes of
XH83_RS23185	COG1305	Transglutaminase-like
XH83_RS23210	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XH83_RS23225	COG5425	PFAM Usg family protein
XH83_RS23230	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XH83_RS23235	COG0459	protein refolding
XH83_RS23245	COG0681	Belongs to the peptidase S26 family
XH83_RS23255	COG1335	isochorismatase
XH83_RS23260	COG0625	glutathione transferase activity
XH83_RS23275	COG0488	(ABC) transporter
XH83_RS23280	COG1126	abc transporter atp-binding protein
XH83_RS23295	COG0559	Belongs to the binding-protein-dependent transport system permease family
XH83_RS23360	COG0384	phenazine biosynthesis protein PhzF
XH83_RS23370	COG0842	Transport permease protein
XH83_RS23375	COG1131	(ABC) transporter
XH83_RS23385	COG1309	transcriptional regulator
XH83_RS23390	COG0640	Transcriptional regulator
XH83_RS23430	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XH83_RS23435	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XH83_RS23435	COG3608	succinylglutamate desuccinylase aspartoacylase
XH83_RS23470	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
XH83_RS23475	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XH83_RS23480	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XH83_RS23520	COG2204	response regulator
XH83_RS23525	COG4191	Histidine kinase
XH83_RS23525	COG0784	Response regulator, receiver
XH83_RS23530	COG3191	aminopeptidase activity
XH83_RS23565	COG0515	serine threonine protein kinase
XH83_RS23565	COG2815	serine threonine protein kinase
XH83_RS23605	COG1309	transcriptional regulator
XH83_RS23610	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
XH83_RS23615	COG1473	amidohydrolase
XH83_RS23620	COG0318	PFAM AMP-dependent synthetase and ligase
XH83_RS23625	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XH83_RS23660	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
XH83_RS23665	COG3668	Plasmid stabilization system
XH83_RS23685	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XH83_RS23690	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XH83_RS23695	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XH83_RS23700	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
XH83_RS23730	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XH83_RS23745	COG3181	Tripartite tricarboxylate transporter family receptor
XH83_RS23750	COG0047	phosphoribosylformylglycinamidine synthase activity
XH83_RS23755	COG0598	Magnesium transport protein CorA
XH83_RS23760	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XH83_RS23765	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XH83_RS23785	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
XH83_RS23790	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XH83_RS23790	COG1116	anion transmembrane transporter activity
XH83_RS23795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XH83_RS23800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XH83_RS23830	COG2020	methyltransferase activity
XH83_RS23845	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
XH83_RS23850	COG0538	isocitrate dehydrogenase activity
XH83_RS23860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XH83_RS23865	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XH83_RS23870	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XH83_RS23875	COG0509	glycine decarboxylation via glycine cleavage system
XH83_RS23880	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XH83_RS23880	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XH83_RS23885	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XH83_RS23970	COG0640	Transcriptional regulator
XH83_RS23975	COG0446	pyridine nucleotide-disulphide oxidoreductase
XH83_RS24045	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XH83_RS24050	COG0737	Belongs to the 5'-nucleotidase family
XH83_RS24085	COG0785	Cytochrome C biogenesis protein
XH83_RS24095	COG0640	Transcriptional regulator
XH83_RS24150	COG2917	probably involved in intracellular septation
XH83_RS24165	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
XH83_RS24165	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
XH83_RS24215	COG1684	flagellar biosynthetic protein fliR
XH83_RS24220	COG1987	bacterial-type flagellum assembly
XH83_RS24225	COG1677	Flagellar hook-basal body complex protein FliE
XH83_RS24230	COG1558	bacterial-type flagellum-dependent cell motility
XH83_RS24245	COG1338	Plays a role in the flagellum-specific transport system
XH83_RS24295	COG4786	Flagellar basal body rod
XH83_RS24300	COG4786	Flagellar basal body rod
XH83_RS24310	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
XH83_RS24315	COG3971	2-oxopent-4-enoate hydratase activity
XH83_RS24330	COG2910	NAD(P)H-binding
XH83_RS24335	COG1733	regulation of RNA biosynthetic process
XH83_RS24345	COG1706	bacterial-type flagellum-dependent cell motility
XH83_RS24365	COG5442	Flagellar protein FlaF
XH83_RS24370	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XH83_RS24375	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XH83_RS24380	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XH83_RS24385	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XH83_RS24390	COG5443	negative regulation of bacterial-type flagellum assembly
XH83_RS24395	COG0076	glutamate decarboxylase activity
XH83_RS24420	COG1256	bacterial-type flagellum assembly
XH83_RS24425	COG1749	Flagellar hook protein flgE
XH83_RS24430	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XH83_RS24435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XH83_RS24460	COG2267	carboxylic ester hydrolase activity
XH83_RS24480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XH83_RS24495	COG5001	Diguanylate cyclase
XH83_RS24495	COG3300	MHYT domain
XH83_RS24505	COG3685	Protein conserved in bacteria
XH83_RS24520	COG2271	Major facilitator Superfamily
XH83_RS24525	COG0583	DNA-binding transcription factor activity
XH83_RS24530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XH83_RS24535	COG4948	Mandelate Racemase Muconate Lactonizing
XH83_RS24540	COG1012	belongs to the aldehyde dehydrogenase family
XH83_RS24545	COG2721	sulfolactate sulfo-lyase activity
XH83_RS24565	COG0492	ferredoxin-NADP+ reductase activity
XH83_RS24575	COG0633	Ferredoxin
XH83_RS24595	COG2198	Histidine kinase
XH83_RS24595	COG0784	Response regulator, receiver
XH83_RS24595	COG2205	protein histidine kinase activity
XH83_RS24610	COG3218	ABC-type transport auxiliary lipoprotein component
XH83_RS24610	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XH83_RS24615	COG1127	ABC transporter
XH83_RS24620	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XH83_RS24625	COG4948	Mandelate Racemase Muconate Lactonizing
XH83_RS24630	COG2814	Major facilitator Superfamily
XH83_RS24675	COG0351	phosphomethylpyrimidine kinase
XH83_RS24680	COG4191	Histidine kinase
XH83_RS24680	COG0784	Response regulator, receiver
XH83_RS24690	COG2010	Cytochrome c
XH83_RS24705	COG3909	cytochrome
XH83_RS24735	COG0673	inositol 2-dehydrogenase activity
XH83_RS24755	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XH83_RS24780	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
XH83_RS24780	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
XH83_RS24790	COG0859	PFAM glycosyl transferase family 9
XH83_RS24815	COG1132	(ABC) transporter
XH83_RS24845	COG2072	flavoprotein involved in K transport
XH83_RS24855	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
XH83_RS24860	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XH83_RS24875	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
XH83_RS24885	COG1137	ATPase activity
XH83_RS24950	COG0318	PFAM AMP-dependent synthetase and ligase
XH83_RS24955	COG0559	Belongs to the binding-protein-dependent transport system permease family
XH83_RS24975	COG2942	2-epimerase
XH83_RS24980	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
XH83_RS25055	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XH83_RS25085	COG2089	acid synthase
XH83_RS25090	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XH83_RS25100	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
XH83_RS25105	COG1086	Polysaccharide biosynthesis protein
XH83_RS25110	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XH83_RS25115	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XH83_RS25120	COG0107	imidazoleglycerol-phosphate synthase activity
XH83_RS25125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XH83_RS25135	COG1045	serine acetyltransferase
XH83_RS25160	COG0110	maltose O-acetyltransferase activity
XH83_RS25170	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XH83_RS25175	COG2755	lipolytic protein G-D-S-L family
XH83_RS25175	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XH83_RS25205	COG1215	transferase activity, transferring glycosyl groups
XH83_RS25230	COG2226	methyltransferase
XH83_RS25235	COG0110	maltose O-acetyltransferase activity
XH83_RS25245	COG0367	asparagine synthase
XH83_RS25255	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
XH83_RS25265	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH83_RS25270	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XH83_RS25295	COG3959	Transketolase, thiamine diphosphate binding domain
XH83_RS25300	COG3958	Transketolase
XH83_RS25305	COG0463	Glycosyl transferase, family 2
XH83_RS25345	COG1024	Enoyl-CoA hydratase
XH83_RS25350	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XH83_RS25355	COG2271	Major facilitator Superfamily
XH83_RS25360	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XH83_RS25370	COG0247	lactate metabolic process
XH83_RS25370	COG0277	FAD linked oxidase domain protein
XH83_RS25380	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
XH83_RS25390	COG0243	molybdopterin cofactor binding
XH83_RS25395	COG3181	Tripartite tricarboxylate transporter family receptor
XH83_RS25400	COG2080	2 iron, 2 sulfur cluster binding
XH83_RS25405	COG2010	Cytochrome c
XH83_RS25405	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XH83_RS25415	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS25430	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XH83_RS25435	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
XH83_RS25445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XH83_RS25450	COG2010	Cytochrome c
XH83_RS25455	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XH83_RS25455	COG3218	ABC-type transport auxiliary lipoprotein component
XH83_RS25460	COG1127	ABC transporter
XH83_RS25480	COG0045	succinate-CoA ligase (ADP-forming) activity
XH83_RS25480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XH83_RS25480	COG1042	CoA-binding domain protein
XH83_RS25505	COG3243	poly(R)-hydroxyalkanoic acid synthase
XH83_RS25510	COG0517	IMP dehydrogenase activity
XH83_RS25510	COG0617	tRNA 3'-terminal CCA addition
XH83_RS25510	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
XH83_RS25515	COG0251	oxidation-reduction process
XH83_RS25550	COG1024	Enoyl-CoA hydratase
XH83_RS25555	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS25570	COG0318	PFAM AMP-dependent synthetase and ligase
XH83_RS25580	COG1250	3-hydroxyacyl-CoA dehydrogenase
XH83_RS25590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XH83_RS25595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XH83_RS25605	COG0129	dihydroxy-acid dehydratase activity
XH83_RS25615	COG2084	Dehydrogenase
XH83_RS25620	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XH83_RS25670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XH83_RS25725	COG2200	EAL domain
XH83_RS25760	COG3920	Histidine kinase
XH83_RS25760	COG2202	Pas domain
XH83_RS25765	COG1914	H( )-stimulated, divalent metal cation uptake system
XH83_RS25780	COG2197	response regulator
XH83_RS25850	COG1793	dna ligase
XH83_RS25870	COG1716	ATPase activity
XH83_RS25870	COG5001	Diguanylate cyclase
XH83_RS25890	COG2010	Cytochrome c
XH83_RS25975	COG3845	ABC transporter
XH83_RS25980	COG4603	Belongs to the binding-protein-dependent transport system permease family
XH83_RS25985	COG1079	Belongs to the binding-protein-dependent transport system permease family
XH83_RS26005	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XH83_RS26005	COG2080	2 iron, 2 sulfur cluster binding
XH83_RS26050	COG0235	Class ii aldolase
XH83_RS26055	COG2095	MarC family integral membrane protein
XH83_RS26075	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
XH83_RS26085	COG0776	regulation of translation
XH83_RS26090	COG0183	Belongs to the thiolase family
XH83_RS26095	COG2723	6-phospho-beta-galactosidase activity
XH83_RS26115	COG4772	TonB-dependent receptor
XH83_RS26120	COG3851	Histidine kinase
XH83_RS26125	COG2197	response regulator
XH83_RS26130	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
XH83_RS26150	COG1131	(ABC) transporter
XH83_RS26280	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
XH83_RS26285	COG3791	Glutathione-dependent formaldehyde-activating
XH83_RS26310	COG0723	plastoquinol--plastocyanin reductase activity
XH83_RS26320	COG1250	3-hydroxyacyl-CoA dehydrogenase
XH83_RS26410	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XH83_RS26415	COG2986	histidine ammonia-lyase
XH83_RS26420	COG1228	amidohydrolase
XH83_RS26425	COG1228	amidohydrolase
XH83_RS26440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XH83_RS26445	COG1116	anion transmembrane transporter activity
XH83_RS26455	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XH83_RS26470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XH83_RS26475	COG1136	(ABC) transporter
XH83_RS26475	COG0577	efflux transmembrane transporter activity
XH83_RS26490	COG2223	nitrite transmembrane transporter activity
XH83_RS26500	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XH83_RS26535	COG3685	Protein conserved in bacteria
XH83_RS26540	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS26570	COG5441	Belongs to the UPF0261 family
XH83_RS26575	COG5564	TIM-barrel signal transduction protein
XH83_RS26580	COG2268	Band 7 protein
XH83_RS26580	COG2268	Band 7 protein
XH83_RS26625	COG3618	amidohydrolase
XH83_RS26635	COG3386	PFAM SMP-30 Gluconolaconase
XH83_RS26640	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XH83_RS26650	COG0826	peptidase U32
XH83_RS26655	COG3154	lipid carrier protein
XH83_RS26660	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
XH83_RS26670	COG2151	metal-sulfur cluster biosynthetic enzyme
XH83_RS26690	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
XH83_RS26700	COG1609	Transcriptional regulator
XH83_RS26710	COG0673	inositol 2-dehydrogenase activity
XH83_RS26715	COG0395	ABC-type sugar transport system, permease component
XH83_RS26720	COG1175	transmembrane transport
XH83_RS26735	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XH83_RS26740	COG1126	abc transporter atp-binding protein
XH83_RS26750	COG0765	amino acid transport
XH83_RS26755	COG0765	amino acid transport
XH83_RS26760	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XH83_RS26765	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XH83_RS26770	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH83_RS26775	COG2030	dehydratase
XH83_RS26785	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XH83_RS26820	COG2207	Transcriptional regulator
XH83_RS26830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XH83_RS26835	COG4689	acetoacetate decarboxylase
XH83_RS26855	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS26925	COG3684	Belongs to the aldolase LacD family
XH83_RS26930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XH83_RS26935	COG3842	ATPase activity
XH83_RS26940	COG1063	alcohol dehydrogenase
XH83_RS26955	COG1653	transport
XH83_RS26990	COG0583	DNA-binding transcription factor activity
XH83_RS27000	COG1902	pentaerythritol trinitrate reductase activity
XH83_RS27005	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XH83_RS27010	COG0625	glutathione transferase activity
XH83_RS27015	COG0625	glutathione transferase activity
XH83_RS27105	COG0628	permease
XH83_RS27125	COG3387	PFAM Glycoside hydrolase 15-related
XH83_RS27130	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS27165	COG0028	Belongs to the TPP enzyme family
XH83_RS27175	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XH83_RS27180	COG0243	molybdopterin cofactor binding
XH83_RS27190	COG0437	4 iron, 4 sulfur cluster binding
XH83_RS27225	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XH83_RS27235	COG1845	cytochrome c oxidase, subunit III
XH83_RS27260	COG5487	UPF0391 membrane protein
XH83_RS27285	COG1295	ribonuclease BN
XH83_RS27290	COG4993	Dehydrogenase
XH83_RS27300	COG3842	ATPase activity
XH83_RS27305	COG1175	transmembrane transport
XH83_RS27310	COG0395	ABC-type sugar transport system, permease component
XH83_RS27390	COG3920	Histidine kinase
XH83_RS27415	COG0745	RESPONSE REGULATOR receiver
XH83_RS27445	COG0438	transferase activity, transferring glycosyl groups
XH83_RS27475	COG2943	transferase activity, transferring hexosyl groups
XH83_RS27480	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XH83_RS27490	COG3387	PFAM Glycoside hydrolase 15-related
XH83_RS27495	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS27510	COG4191	Histidine kinase
XH83_RS27510	COG0784	Response regulator, receiver
XH83_RS27515	COG0784	Response regulator, receiver
XH83_RS27520	COG4251	negative regulation of phosphorylation
XH83_RS27530	COG0484	heat shock protein binding
XH83_RS27625	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XH83_RS27655	COG0673	inositol 2-dehydrogenase activity
XH83_RS27660	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XH83_RS27670	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
XH83_RS27675	COG0297	glycogen (starch) synthase activity
XH83_RS27680	COG4095	Psort location CytoplasmicMembrane, score
XH83_RS27685	COG3384	dioxygenase
XH83_RS27705	COG2072	flavoprotein involved in K transport
XH83_RS27725	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XH83_RS27755	COG0281	malic enzyme
XH83_RS27765	COG0668	transmembrane transport
XH83_RS27775	COG2326	polyphosphate kinase activity
XH83_RS27840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XH83_RS27850	COG0517	IMP dehydrogenase activity
XH83_RS27850	COG1125	glycine betaine transport
XH83_RS27855	COG1174	glycine betaine transport
XH83_RS27875	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS27885	COG5001	Diguanylate cyclase
XH83_RS27885	COG3300	MHYT domain
XH83_RS27890	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XH83_RS27910	COG0440	acetolactate synthase activity
XH83_RS27915	COG0028	Belongs to the TPP enzyme family
XH83_RS27920	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XH83_RS27925	COG0560	Phosphoserine phosphatase
XH83_RS27940	COG0330	HflC and HflK could
XH83_RS27945	COG0330	HflC and HflK could
XH83_RS27960	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
XH83_RS28000	COG0114	fumarate hydratase activity
XH83_RS28035	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XH83_RS28040	COG4191	Histidine kinase
XH83_RS28040	COG0784	Response regulator, receiver
XH83_RS28060	COG2124	cytochrome p450
XH83_RS28065	COG1309	transcriptional regulator
XH83_RS28090	COG0828	Belongs to the bacterial ribosomal protein bS21 family
XH83_RS28095	COG1278	Cold shock
XH83_RS28120	COG2200	EAL domain
XH83_RS28120	COG2202	Pas domain
XH83_RS28120	COG2199	diguanylate cyclase activity
XH83_RS28125	COG2271	Major facilitator Superfamily
XH83_RS28130	COG5001	Diguanylate cyclase
XH83_RS28130	COG3300	MHYT domain
XH83_RS28140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XH83_RS28150	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XH83_RS28170	COG0277	FAD linked oxidase domain protein
XH83_RS28180	COG5487	UPF0391 membrane protein
XH83_RS28185	COG0210	DNA helicase
XH83_RS28230	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
XH83_RS28255	COG2267	carboxylic ester hydrolase activity
XH83_RS28265	COG1131	(ABC) transporter
XH83_RS28270	COG0842	Transport permease protein
XH83_RS28285	COG0584	glycerophosphoryl diester phosphodiesterase
XH83_RS28305	COG2264	protein methyltransferase activity
XH83_RS28320	COG0006	proline dipeptidase activity
XH83_RS28325	COG2814	Major facilitator Superfamily
XH83_RS28330	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XH83_RS28340	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XH83_RS28350	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
XH83_RS28355	COG0849	cell division
XH83_RS28360	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XH83_RS28365	COG1181	Belongs to the D-alanine--D-alanine ligase family
XH83_RS28370	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XH83_RS28375	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XH83_RS28380	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XH83_RS28390	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
XH83_RS28395	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XH83_RS28400	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XH83_RS28405	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XH83_RS28420	COG0275	rRNA processing
XH83_RS28425	COG3023	N-Acetylmuramoyl-L-alanine amidase
XH83_RS28430	COG4941	Belongs to the sigma-70 factor family
XH83_RS28435	COG3795	YCII-related domain
XH83_RS28450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XH83_RS28475	COG5265	(ABC) transporter
XH83_RS28490	COG1309	transcriptional regulator
XH83_RS28510	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XH83_RS28515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XH83_RS28520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XH83_RS28550	COG0688	phosphatidylethanolamine metabolic process
XH83_RS28575	COG1376	ErfK ybiS ycfS ynhG family protein
XH83_RS28575	COG1388	LysM domain
XH83_RS28610	COG3842	ATPase activity
XH83_RS28620	COG1176	ABC-type spermidine putrescine transport system, permease component I
XH83_RS28670	COG2022	thiamine diphosphate biosynthetic process
XH83_RS28680	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
XH83_RS28695	COG0625	glutathione transferase activity
XH83_RS28725	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS28730	COG2204	response regulator
XH83_RS28750	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XH83_RS28820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XH83_RS28825	COG1376	ErfK ybiS ycfS ynhG family protein
XH83_RS28835	COG2897	thiosulfate sulfurtransferase activity
XH83_RS28840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XH83_RS28855	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XH83_RS28865	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XH83_RS28880	COG2207	Transcriptional regulator
XH83_RS28880	COG3708	Transcriptional regulator
XH83_RS28885	COG4948	Mandelate Racemase Muconate Lactonizing
XH83_RS28910	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XH83_RS28910	COG1672	PFAM Archaeal ATPase
XH83_RS28925	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XH83_RS28930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XH83_RS28935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH83_RS28940	COG0601	transmembrane transport
XH83_RS28945	COG0747	negative chemotaxis
XH83_RS28970	COG2072	flavoprotein involved in K transport
XH83_RS29010	COG0475	glutathione-regulated potassium exporter activity
XH83_RS29030	COG4948	Mandelate Racemase Muconate Lactonizing
XH83_RS29040	COG0386	Belongs to the glutathione peroxidase family
XH83_RS29045	COG0154	amidase activity
XH83_RS29060	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
XH83_RS29065	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
XH83_RS29070	COG0535	radical SAM domain protein
XH83_RS29075	COG0535	radical SAM domain protein
XH83_RS29095	COG0674	pyruvate-flavodoxin oxidoreductase activity
XH83_RS29095	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
XH83_RS29100	COG1013	pyruvate-flavodoxin oxidoreductase activity
XH83_RS29145	COG2719	SpoVR family
XH83_RS29150	COG2718	Belongs to the UPF0229 family
XH83_RS29155	COG2766	serine protein kinase
XH83_RS29170	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XH83_RS29175	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XH83_RS29180	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XH83_RS29185	COG0363	glucosamine-6-phosphate deaminase activity
XH83_RS29190	COG3265	gluconokinase activity
XH83_RS29200	COG3387	PFAM Glycoside hydrolase 15-related
XH83_RS29205	COG1640	4-alpha-glucanotransferase
XH83_RS29210	COG0366	Alpha amylase catalytic
XH83_RS29215	COG0366	Alpha amylase catalytic
XH83_RS29220	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XH83_RS29230	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XH83_RS29255	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
XH83_RS29260	COG0745	RESPONSE REGULATOR receiver
XH83_RS29265	COG2205	protein histidine kinase activity
XH83_RS29270	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
XH83_RS29275	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XH83_RS29280	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XH83_RS29340	COG1749	Flagellar hook protein flgE
XH83_RS29345	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XH83_RS29365	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
XH83_RS29370	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XH83_RS29375	COG1595	DNA-templated transcription, initiation
XH83_RS29395	COG0427	acetyl-CoA hydrolase
XH83_RS29400	COG0318	PFAM AMP-dependent synthetase and ligase
XH83_RS29420	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
XH83_RS29430	COG2030	dehydratase
XH83_RS29465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XH83_RS29475	COG0071	Belongs to the small heat shock protein (HSP20) family
XH83_RS29485	COG1053	succinate dehydrogenase
XH83_RS29490	COG1414	Transcriptional regulator
XH83_RS29495	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS29505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XH83_RS29510	COG0028	Belongs to the TPP enzyme family
XH83_RS29515	COG1794	racemase activity, acting on amino acids and derivatives
XH83_RS29520	COG2272	Belongs to the type-B carboxylesterase lipase family
XH83_RS29525	COG0477	Major facilitator Superfamily
XH83_RS29530	COG1309	transcriptional regulator
XH83_RS29540	COG1063	alcohol dehydrogenase
XH83_RS29545	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
XH83_RS29555	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XH83_RS29565	COG0246	Mannitol dehydrogenase
XH83_RS29575	COG1234	tRNA 3'-trailer cleavage
XH83_RS29605	COG0412	Dienelactone hydrolase
XH83_RS29645	COG1684	flagellar biosynthetic protein fliR
XH83_RS29650	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XH83_RS29655	COG4794	Type iii secretion
XH83_RS29660	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XH83_RS29665	COG5443	negative regulation of bacterial-type flagellum assembly
XH83_RS29685	COG1749	Flagellar hook protein flgE
XH83_RS29705	COG1360	Flagellar Motor Protein
XH83_RS29720	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XH83_RS29725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XH83_RS29730	COG1338	Plays a role in the flagellum-specific transport system
XH83_RS29740	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
XH83_RS29750	COG1706	bacterial-type flagellum-dependent cell motility
XH83_RS29760	COG4786	Flagellar basal body rod
XH83_RS29765	COG1677	Flagellar hook-basal body complex protein FliE
XH83_RS29770	COG1558	bacterial-type flagellum-dependent cell motility
XH83_RS29775	COG1815	bacterial-type flagellum-dependent cell motility
XH83_RS29780	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XH83_RS29785	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
XH83_RS29790	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
XH83_RS29805	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XH83_RS29815	COG4786	Flagellar basal body rod
XH83_RS29820	COG1157	protein secretion by the type III secretion system
XH83_RS29825	COG1846	Transcriptional regulator
XH83_RS29870	COG4177	L-phenylalanine transmembrane transporter activity
XH83_RS29890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XH83_RS29895	COG1464	Belongs to the NlpA lipoprotein family
XH83_RS29950	COG0482	sulfurtransferase activity
XH83_RS29960	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XH83_RS29970	COG1766	The M ring may be actively involved in energy transduction
XH83_RS29975	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
XH83_RS29985	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
XH83_RS29990	COG2204	response regulator
XH83_RS29995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XH83_RS30005	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XH83_RS30010	COG2124	cytochrome p450
XH83_RS30015	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XH83_RS30020	COG4993	Dehydrogenase
XH83_RS30030	COG3842	ATPase activity
XH83_RS30035	COG1175	transmembrane transport
XH83_RS30040	COG0395	ABC-type sugar transport system, permease component
XH83_RS30045	COG1653	transport
XH83_RS30050	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
XH83_RS30060	COG1063	alcohol dehydrogenase
XH83_RS30070	COG3540	Alkaline phosphatase
XH83_RS30080	COG0395	ABC-type sugar transport system, permease component
XH83_RS30085	COG1175	transmembrane transport
XH83_RS30095	COG1070	Carbohydrate kinase
XH83_RS30105	COG4214	carbohydrate transport
XH83_RS30115	COG4213	ABC transporter substrate-binding protein
XH83_RS30130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XH83_RS30140	COG3005	denitrification pathway
XH83_RS30145	COG3043	anaerobic respiration
XH83_RS30150	COG0348	domain, Protein
XH83_RS30155	COG0437	4 iron, 4 sulfur cluster binding
XH83_RS30175	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XH83_RS30185	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XH83_RS30190	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XH83_RS30235	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XH83_RS30270	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XH83_RS30280	COG1175	transmembrane transport
XH83_RS30285	COG0395	ABC-type sugar transport system, permease component
XH83_RS30300	COG0848	biopolymer transport protein
XH83_RS30320	COG4771	TonB-dependent receptor
XH83_RS30335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XH83_RS30340	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
XH83_RS30350	COG4566	intracellular signal transduction
XH83_RS30375	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XH83_RS30385	COG2847	Copper chaperone PCu(A)C
XH83_RS30420	COG1301	dicarboxylic acid transport
XH83_RS30425	COG2828	Protein conserved in bacteria
XH83_RS30430	COG0583	DNA-binding transcription factor activity
XH83_RS30440	COG1175	transmembrane transport
XH83_RS30455	COG1177	transmembrane transport
XH83_RS30460	COG1176	ABC-type spermidine putrescine transport system, permease component I
XH83_RS30465	COG3842	ATPase activity
XH83_RS30475	COG5001	Diguanylate cyclase
XH83_RS30475	COG3300	MHYT domain
XH83_RS30480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XH83_RS30505	COG5001	Diguanylate cyclase
XH83_RS30505	COG3447	MASE1 domain protein
XH83_RS30505	COG5002	protein histidine kinase activity
XH83_RS30510	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
XH83_RS30515	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
XH83_RS30520	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XH83_RS30525	COG0828	Belongs to the bacterial ribosomal protein bS21 family
XH83_RS30545	COG0387	Pfam Sodium calcium exchanger
XH83_RS30595	COG1164	Oligoendopeptidase f
XH83_RS30600	COG2204	response regulator
XH83_RS30605	COG2989	Protein conserved in bacteria
XH83_RS30620	COG3750	Belongs to the UPF0335 family
XH83_RS30635	COG0469	pyruvate kinase activity
XH83_RS30640	COG1309	transcriptional regulator
XH83_RS30670	COG0463	Glycosyl transferase, family 2
XH83_RS30685	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XH83_RS30690	COG0037	tRNA processing
XH83_RS30700	COG2885	chlorophyll binding
XH83_RS30710	COG5001	Diguanylate cyclase
XH83_RS30715	COG0823	Involved in the tonB-independent uptake of proteins
XH83_RS30740	COG1045	serine acetyltransferase
XH83_RS30755	COG3179	chitinase
XH83_RS30775	COG3795	YCII-related domain
XH83_RS30790	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS30815	COG4941	Belongs to the sigma-70 factor family
XH83_RS30820	COG3795	YCII-related domain
XH83_RS30825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XH83_RS30835	COG1309	transcriptional regulator
XH83_RS30840	COG0625	glutathione transferase activity
XH83_RS30845	COG0840	transmembrane signaling receptor activity
XH83_RS30875	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XH83_RS30885	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS30895	COG1301	dicarboxylic acid transport
XH83_RS30900	COG0488	(ABC) transporter
XH83_RS30930	COG1177	transmembrane transport
XH83_RS30935	COG1176	ABC-type spermidine putrescine transport system, permease component I
XH83_RS30940	COG3842	ATPase activity
XH83_RS30955	COG0519	Catalyzes the synthesis of GMP from XMP
XH83_RS30965	COG0824	Thioesterase
XH83_RS30980	COG1408	metallophosphoesterase
XH83_RS30985	COG2255	four-way junction helicase activity
XH83_RS30990	COG0632	four-way junction helicase activity
XH83_RS30995	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
XH83_RS31000	COG0217	transcriptional regulatory protein
XH83_RS31015	COG1692	metallophosphoesterase
XH83_RS31050	COG0126	phosphoglycerate kinase activity
XH83_RS31060	COG3588	fructose-bisphosphate aldolase
XH83_RS31075	COG0483	inositol monophosphate 1-phosphatase activity
XH83_RS31080	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XH83_RS31085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XH83_RS31090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XH83_RS31095	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XH83_RS31120	COG1132	(ABC) transporter
XH83_RS31125	COG0254	rRNA binding
XH83_RS31140	COG3321	synthase
XH83_RS31140	COG0604	alcohol dehydrogenase
XH83_RS31140	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS31155	COG2203	Gaf domain
XH83_RS31155	COG5001	Diguanylate cyclase
XH83_RS31155	COG4251	negative regulation of phosphorylation
XH83_RS31155	COG3706	GGDEF domain
XH83_RS31160	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XH83_RS31165	COG2951	lytic endotransglycosylase activity
XH83_RS31175	COG3237	CsbD-like
XH83_RS31180	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS31185	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS31195	COG1678	Uncharacterized ACR, COG1678
XH83_RS31215	COG0730	response to heat
XH83_RS31220	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS31235	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XH83_RS31240	COG4208	sulfate ABC transporter
XH83_RS31245	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XH83_RS31250	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XH83_RS31255	COG0175	sulfate reduction
XH83_RS31265	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XH83_RS31290	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XH83_RS31295	COG3237	CsbD-like
XH83_RS31305	COG0840	transmembrane signaling receptor activity
XH83_RS31315	COG1376	ErfK ybiS ycfS ynhG family protein
XH83_RS31315	COG1388	LysM domain
XH83_RS31350	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
XH83_RS31355	COG0830	nickel cation binding
XH83_RS31360	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
XH83_RS31370	COG0804	urea catabolic process
XH83_RS31375	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XH83_RS31380	COG0832	Belongs to the urease beta subunit family
XH83_RS31385	COG0831	urea catabolic process
XH83_RS31390	COG0829	nickel cation binding
XH83_RS31420	COG0513	Belongs to the DEAD box helicase family
XH83_RS31425	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
XH83_RS31430	COG1278	Cold shock
XH83_RS31475	COG4964	Belongs to the GSP D family
XH83_RS31515	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XH83_RS31520	COG0791	NLP P60 protein
XH83_RS31525	COG4172	Belongs to the ABC transporter superfamily
XH83_RS31530	COG4239	(ABC) transporter, permease
XH83_RS31535	COG4174	ABC transporter (Permease)
XH83_RS31540	COG4166	transmembrane transport
XH83_RS31545	COG4166	transmembrane transport
XH83_RS31550	COG3474	cytochrome
XH83_RS31555	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XH83_RS31560	COG0077	Prephenate dehydratase
XH83_RS31560	COG1605	Chorismate mutase
XH83_RS31570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XH83_RS31590	COG0640	Transcriptional regulator
XH83_RS31595	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XH83_RS31605	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XH83_RS31620	COG1960	acyl-CoA dehydrogenase activity
XH83_RS31625	COG0183	Belongs to the thiolase family
XH83_RS31630	COG0318	PFAM AMP-dependent synthetase and ligase
XH83_RS31710	COG0583	DNA-binding transcription factor activity
XH83_RS31735	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
XH83_RS31745	COG1024	Enoyl-CoA hydratase
XH83_RS31750	COG0300	oxidoreductase activity
XH83_RS31750	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS31750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XH83_RS31750	COG0318	PFAM AMP-dependent synthetase and ligase
XH83_RS31750	COG3321	synthase
XH83_RS31810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XH83_RS31815	COG1024	Enoyl-CoA hydratase
XH83_RS31825	COG2378	regulation of single-species biofilm formation
XH83_RS31845	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XH83_RS31850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XH83_RS31865	COG0604	alcohol dehydrogenase
XH83_RS31875	COG2186	Transcriptional regulator
XH83_RS31885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XH83_RS31890	COG1129	ABC transporter
XH83_RS31890	COG0842	Transport permease protein
XH83_RS31895	COG0842	Transport permease protein
XH83_RS31910	COG1672	PFAM Archaeal ATPase
XH83_RS31910	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XH83_RS31925	COG0596	Alpha beta hydrolase
XH83_RS31945	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS31955	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS31970	COG0179	Fumarylacetoacetate (FAA) hydrolase
XH83_RS31985	COG0596	Alpha beta hydrolase
XH83_RS31995	COG0154	amidase activity
XH83_RS32015	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
XH83_RS32020	COG1960	acyl-CoA dehydrogenase activity
XH83_RS32030	COG1024	Enoyl-CoA hydratase
XH83_RS32045	COG0583	DNA-binding transcription factor activity
XH83_RS32070	COG1058	Belongs to the CinA family
XH83_RS32070	COG1546	Belongs to the CinA family
XH83_RS32080	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
XH83_RS32085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XH83_RS32090	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
XH83_RS32100	COG0444	Belongs to the ABC transporter superfamily
XH83_RS32105	COG0154	amidase activity
XH83_RS32115	COG4608	Belongs to the ABC transporter superfamily
XH83_RS32120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH83_RS32130	COG0747	negative chemotaxis
XH83_RS32135	COG4166	transmembrane transport
XH83_RS32225	COG2309	aminopeptidase activity
XH83_RS32230	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
XH83_RS32255	COG2070	2-Nitropropane dioxygenase
XH83_RS32260	COG0318	PFAM AMP-dependent synthetase and ligase
XH83_RS32275	COG1027	Aspartate ammonia-lyase
XH83_RS32285	COG1238	metal cluster binding
XH83_RS32290	COG0140	phosphoribosyl-ATP diphosphatase activity
XH83_RS32305	COG1132	(ABC) transporter
XH83_RS32310	COG1686	Belongs to the peptidase S11 family
XH83_RS32315	COG0318	PFAM AMP-dependent synthetase and ligase
XH83_RS32325	COG0678	peroxiredoxin activity
XH83_RS32325	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
XH83_RS32335	COG0328	RNA-DNA hybrid ribonuclease activity
XH83_RS32340	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
XH83_RS32345	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XH83_RS32355	COG3047	cAMP biosynthetic process
XH83_RS32380	COG0025	NhaP-type Na H and K H
XH83_RS32390	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS32405	COG2358	TRAP transporter, solute receptor (TAXI family
XH83_RS32435	COG0667	Aldo Keto reductase
XH83_RS32460	COG1022	Amp-dependent synthetase and ligase
XH83_RS32470	COG1335	isochorismatase
XH83_RS32505	COG1595	DNA-templated transcription, initiation
XH83_RS32510	COG3806	Anti-sigma factor
XH83_RS32515	COG1595	DNA-templated transcription, initiation
XH83_RS32545	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XH83_RS32560	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
XH83_RS32565	COG0424	maF-like protein
XH83_RS32570	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XH83_RS32575	COG5328	Belongs to the UPF0262 family
XH83_RS32580	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XH83_RS32590	COG0702	epimerase
XH83_RS32620	COG3634	alkyl hydroperoxide reductase activity
XH83_RS32640	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XH83_RS32655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XH83_RS32670	COG3971	2-oxopent-4-enoate hydratase activity
XH83_RS32675	COG0179	Fumarylacetoacetate (FAA) hydrolase
XH83_RS32680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XH83_RS32685	COG3181	Tripartite tricarboxylate transporter family receptor
XH83_RS32715	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS32725	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
XH83_RS32730	COG3454	Phosphonate metabolism
XH83_RS32735	COG4778	phosphonate C-P lyase system protein PhnL
XH83_RS32740	COG4107	phosphonate C-P lyase system protein PhnK
XH83_RS32745	COG3627	carbon phosphorus lyase activity
XH83_RS32750	COG3626	phosphonate metabolism
XH83_RS32755	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
XH83_RS32760	COG3624	Phosphonate C-P lyase system protein PhnG
XH83_RS32765	COG2188	Transcriptional regulator
XH83_RS32785	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
XH83_RS32795	COG3454	Phosphonate metabolism
XH83_RS32800	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
XH83_RS32815	COG1024	Enoyl-CoA hydratase
XH83_RS32825	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
XH83_RS32830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XH83_RS32845	COG4774	siderophore transport
XH83_RS32850	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XH83_RS32855	COG0277	FAD linked oxidase domain protein
XH83_RS32860	COG1802	Transcriptional regulator
XH83_RS32880	COG1032	radical SAM domain protein
XH83_RS32890	COG1959	2 iron, 2 sulfur cluster binding
XH83_RS32920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XH83_RS32940	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
XH83_RS33015	COG2264	protein methyltransferase activity
XH83_RS33025	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XH83_RS33030	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XH83_RS33055	COG1024	Enoyl-CoA hydratase
XH83_RS33070	COG0720	synthase
XH83_RS33080	COG3852	Histidine kinase
XH83_RS33085	COG0230	Belongs to the bacterial ribosomal protein bL34 family
XH83_RS33090	COG0594	ribonuclease P activity
XH83_RS33095	COG0706	membrane insertase activity
XH83_RS33100	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XH83_RS33110	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XH83_RS33125	COG2171	N-acyltransferase activity
XH83_RS33135	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XH83_RS33140	COG0101	tRNA pseudouridine synthase activity
XH83_RS33145	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XH83_RS33150	COG0242	peptide deformylase activity
XH83_RS33165	COG2223	nitrite transmembrane transporter activity
XH83_RS33175	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
XH83_RS33180	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XH83_RS33185	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
XH83_RS33200	COG0765	amino acid transport
XH83_RS33205	COG1126	abc transporter atp-binding protein
XH83_RS33230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XH83_RS33235	COG1522	sequence-specific DNA binding
XH83_RS33240	COG2205	protein histidine kinase activity
XH83_RS33265	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XH83_RS33280	COG3577	Aspartyl protease
XH83_RS33285	COG1643	Atp-dependent helicase
XH83_RS33290	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
XH83_RS33300	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XH83_RS33300	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XH83_RS33310	COG0641	radical SAM
XH83_RS33320	COG1280	lysine exporter protein (LysE YggA)
XH83_RS33325	COG0625	glutathione transferase activity
XH83_RS33330	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XH83_RS33350	COG1201	RNA secondary structure unwinding
XH83_RS33360	COG0251	oxidation-reduction process
XH83_RS33385	COG1999	signal sequence binding
XH83_RS33395	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
XH83_RS33435	COG0167	dihydroorotate dehydrogenase activity
XH83_RS33445	COG1234	tRNA 3'-trailer cleavage
XH83_RS33490	COG1172	Belongs to the binding-protein-dependent transport system permease family
XH83_RS33495	COG1129	ABC transporter
XH83_RS33500	COG2115	Belongs to the xylose isomerase family
XH83_RS33505	COG1070	Carbohydrate kinase
XH83_RS33525	COG1396	sequence-specific DNA binding
XH83_RS33530	COG2267	carboxylic ester hydrolase activity
XH83_RS33645	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
XH83_RS33650	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
XH83_RS33650	COG2207	Transcriptional regulator
XH83_RS33690	COG4191	Histidine kinase
XH83_RS33695	COG0717	Belongs to the dCTP deaminase family
XH83_RS33720	COG2967	ApaG domain
XH83_RS33730	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XH83_RS33735	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XH83_RS33745	COG0745	RESPONSE REGULATOR receiver
XH83_RS33750	COG0704	Plays a role in the regulation of phosphate uptake
XH83_RS33755	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XH83_RS33760	COG0581	inorganic phosphate transmembrane transporter activity
XH83_RS33765	COG0573	inorganic phosphate transmembrane transporter activity
XH83_RS33770	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XH83_RS33775	COG5002	protein histidine kinase activity
XH83_RS33790	COG0596	Alpha beta hydrolase
XH83_RS33805	COG1360	Flagellar Motor Protein
XH83_RS33840	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XH83_RS33845	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XH83_RS33865	COG4638	Rieske (2fe-2S)
XH83_RS33875	COG4774	siderophore transport
XH83_RS33910	COG3916	Acyl-homoserine-lactone synthase
XH83_RS33915	COG2197	response regulator
XH83_RS33930	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XH83_RS33945	COG4177	L-phenylalanine transmembrane transporter activity
XH83_RS33960	COG0673	inositol 2-dehydrogenase activity
XH83_RS33975	COG1252	NADH dehydrogenase
XH83_RS33990	COG2124	cytochrome p450
XH83_RS34015	COG1802	Transcriptional regulator
XH83_RS34035	COG4172	Belongs to the ABC transporter superfamily
XH83_RS34040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH83_RS34045	COG0601	transmembrane transport
XH83_RS34050	COG0747	negative chemotaxis
XH83_RS34065	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XH83_RS34070	COG4191	Histidine kinase
XH83_RS34070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XH83_RS34075	COG0784	Response regulator, receiver
XH83_RS34075	COG3437	response regulator, receiver
XH83_RS34085	COG1595	DNA-templated transcription, initiation
XH83_RS34110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XH83_RS34115	COG1960	acyl-CoA dehydrogenase activity
XH83_RS34120	COG1960	acyl-CoA dehydrogenase activity
XH83_RS34130	COG2514	catechol 2,3-dioxygenase activity
XH83_RS34140	COG2814	Major facilitator Superfamily
XH83_RS34145	COG1505	serine-type exopeptidase activity
XH83_RS34180	COG0737	Belongs to the 5'-nucleotidase family
XH83_RS34200	COG2271	Major facilitator Superfamily
XH83_RS34210	COG2271	Major facilitator Superfamily
XH83_RS34230	COG3788	relative of glutathione S-transferase, MAPEG superfamily
XH83_RS34240	COG0683	leucine binding
XH83_RS34250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XH83_RS34270	COG0601	transmembrane transport
XH83_RS34275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH83_RS34280	COG0444	Belongs to the ABC transporter superfamily
XH83_RS34285	COG4608	Belongs to the ABC transporter superfamily
XH83_RS34305	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XH83_RS34310	COG3246	L-lysine catabolic process to acetate
XH83_RS34325	COG1960	acyl-CoA dehydrogenase activity
XH83_RS34330	COG1960	acyl-CoA dehydrogenase activity
XH83_RS34370	COG1215	transferase activity, transferring glycosyl groups
XH83_RS34390	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XH83_RS34410	COG1129	ABC transporter
XH83_RS34430	COG0784	Response regulator, receiver
XH83_RS34430	COG5002	protein histidine kinase activity
XH83_RS34430	COG2198	Histidine kinase
XH83_RS34435	COG0745	RESPONSE REGULATOR receiver
XH83_RS34440	COG2072	flavoprotein involved in K transport
XH83_RS34460	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
XH83_RS34465	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XH83_RS34470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XH83_RS34480	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XH83_RS34490	COG3300	MHYT domain
XH83_RS34490	COG5001	Diguanylate cyclase
XH83_RS34510	COG3300	MHYT domain
XH83_RS34510	COG5001	Diguanylate cyclase
XH83_RS34525	COG0333	Belongs to the bacterial ribosomal protein bL32 family
XH83_RS34530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XH83_RS34535	COG0142	geranyltranstransferase activity
XH83_RS34565	COG0025	NhaP-type Na H and K H
XH83_RS34580	COG2175	clavaminate synthase activity
XH83_RS34585	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XH83_RS34595	COG0735	belongs to the Fur family
XH83_RS34605	COG1566	PFAM secretion protein HlyD family protein
XH83_RS34610	COG2814	Major facilitator Superfamily
XH83_RS34620	COG0840	transmembrane signaling receptor activity
XH83_RS34625	COG3485	protocatechuate 3,4-dioxygenase
XH83_RS34630	COG3485	protocatechuate 3,4-dioxygenase
XH83_RS34640	COG0183	Belongs to the thiolase family
XH83_RS34645	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XH83_RS34670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XH83_RS34680	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XH83_RS34720	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XH83_RS34745	COG1131	(ABC) transporter
XH83_RS34755	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XH83_RS34770	COG0366	Alpha amylase catalytic
XH83_RS34780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XH83_RS34785	COG1733	regulation of RNA biosynthetic process
XH83_RS34800	COG0477	Major facilitator Superfamily
XH83_RS34815	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS34825	COG5001	Diguanylate cyclase
XH83_RS34830	COG3829	transcription factor binding
XH83_RS34830	COG3290	protein histidine kinase activity
XH83_RS34870	COG5001	Diguanylate cyclase
XH83_RS34875	COG3706	GGDEF domain
XH83_RS34895	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XH83_RS34915	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XH83_RS34930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XH83_RS34975	COG0596	Alpha beta hydrolase
XH83_RS34985	COG0412	Dienelactone hydrolase
XH83_RS35000	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XH83_RS35010	COG0268	Binds directly to 16S ribosomal RNA
XH83_RS35020	COG1475	DNA binding
XH83_RS35025	COG1414	Transcriptional regulator
XH83_RS35030	COG0459	protein refolding
XH83_RS35035	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XH83_RS35080	COG2963	transposase activity
XH83_RS35085	COG3436	PFAM IS66 Orf2 family protein
XH83_RS35095	COG3318	Belongs to the UPF0149 family
XH83_RS35135	COG4717	serine-type aminopeptidase activity
XH83_RS35225	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
XH83_RS35230	COG0546	phosphoglycolate phosphatase activity
XH83_RS35285	COG1609	Transcriptional regulator
XH83_RS35330	COG1129	ABC transporter
XH83_RS35335	COG1172	Belongs to the binding-protein-dependent transport system permease family
XH83_RS35345	COG1175	transmembrane transport
XH83_RS35355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XH83_RS35375	COG2204	response regulator
XH83_RS35375	COG5564	TIM-barrel signal transduction protein
XH83_RS35390	COG0546	phosphoglycolate phosphatase activity
XH83_RS35395	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
XH83_RS35415	COG1024	Enoyl-CoA hydratase
XH83_RS35420	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH83_RS35430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XH83_RS35445	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
XH83_RS35470	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XH83_RS35475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XH83_RS35505	COG1172	Belongs to the binding-protein-dependent transport system permease family
XH83_RS35510	COG1129	ABC transporter
XH83_RS35520	COG2963	transposase activity
XH83_RS35525	COG3436	PFAM IS66 Orf2 family protein
XH83_RS35535	COG3436	PFAM IS66 Orf2 family protein
XH83_RS35560	COG5564	TIM-barrel signal transduction protein
XH83_RS35565	COG1053	succinate dehydrogenase
XH83_RS35575	COG5001	Diguanylate cyclase
XH83_RS35590	COG1346	cytolysis
XH83_RS35595	COG1484	DNA-dependent DNA replication
XH83_RS35600	COG4584	PFAM Integrase catalytic
XH83_RS35655	COG4789	Type iii secretion
XH83_RS35695	COG4669	(LipO)protein
XH83_RS35705	COG1317	bacterial-type flagellum organization
XH83_RS35710	COG1157	protein secretion by the type III secretion system
XH83_RS35720	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
XH83_RS35725	COG4790	Type iii secretion
XH83_RS35730	COG4794	Type iii secretion
XH83_RS35735	COG4791	protein targeting
XH83_RS35740	COG4792	protein secretion
XH83_RS35745	COG5461	TIGRFAM pilus (Caulobacter type) biogenesis lipoprotein CpaD
XH83_RS35755	COG0745	RESPONSE REGULATOR receiver
XH83_RS35760	COG4191	Histidine kinase
XH83_RS35765	COG2963	transposase activity
XH83_RS35770	COG3436	PFAM IS66 Orf2 family protein
XH83_RS35820	COG0473	3-isopropylmalate dehydrogenase activity
XH83_RS35820	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XH83_RS35830	COG1414	Transcriptional regulator
XH83_RS35875	COG0517	IMP dehydrogenase activity
XH83_RS35880	COG4974	Belongs to the 'phage' integrase family
XH83_RS35885	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
XH83_RS35890	COG2086	electron transfer activity
XH83_RS35895	COG1053	succinate dehydrogenase
XH83_RS35900	COG4521	taurine ABC transporter
XH83_RS35905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XH83_RS35910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XH83_RS35920	COG2301	Belongs to the HpcH HpaI aldolase family
XH83_RS35925	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH83_RS35930	COG2855	membrane
XH83_RS35935	COG0583	DNA-binding transcription factor activity
XH83_RS35950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XH83_RS35955	COG0765	amino acid transport
XH83_RS35960	COG0765	amino acid transport
XH83_RS35965	COG1126	abc transporter atp-binding protein
XH83_RS35980	COG0436	Aminotransferase
XH83_RS35990	COG3842	ATPase activity
XH83_RS36000	COG1176	ABC-type spermidine putrescine transport system, permease component I
XH83_RS36005	COG1177	transmembrane transport
XH83_RS36015	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
XH83_RS36020	COG1984	allophanate hydrolase subunit 2
XH83_RS36030	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
XH83_RS36035	COG0439	Biotin carboxylase
XH83_RS36040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH83_RS36045	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
XH83_RS36050	COG0583	DNA-binding transcription factor activity
XH83_RS36055	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
XH83_RS36060	COG1012	belongs to the aldehyde dehydrogenase family
XH83_RS36075	COG1116	anion transmembrane transporter activity
XH83_RS36080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XH83_RS36135	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XH83_RS36150	COG1116	anion transmembrane transporter activity
XH83_RS36155	COG1960	acyl-CoA dehydrogenase activity
XH83_RS36160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XH83_RS36165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XH83_RS36190	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS36200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XH83_RS36205	COG2814	Major facilitator Superfamily
XH83_RS36215	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XH83_RS36220	COG0252	asparaginase activity
XH83_RS36235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XH83_RS36240	COG0165	Argininosuccinate lyase
XH83_RS36245	COG0511	ligase activity, forming carbon-carbon bonds
XH83_RS36250	COG0439	Biotin carboxylase
XH83_RS36270	COG0154	amidase activity
XH83_RS36290	COG3842	ATPase activity
XH83_RS36295	COG1176	ABC-type spermidine putrescine transport system, permease component I
XH83_RS36310	COG0436	Aminotransferase
XH83_RS36315	COG2079	MmgE PrpD family protein
XH83_RS36325	COG1984	allophanate hydrolase subunit 2
XH83_RS36330	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
XH83_RS36345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XH83_RS36360	COG2079	MmgE PrpD family protein
XH83_RS36375	COG3012	SEC-C Motif Domain Protein
XH83_RS36540	COG2801	Transposase and inactivated derivatives
XH83_RS36545	COG3551	Protein conserved in bacteria
XH83_RS36660	COG3621	Patatin-like phospholipase
XH83_RS36700	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XH83_RS36740	COG3311	Transcriptional regulator
XH83_RS36750	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XH83_RS36765	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XH83_RS36785	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XH83_RS36790	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
XH83_RS36820	COG0251	oxidation-reduction process
XH83_RS36825	COG2072	flavoprotein involved in K transport
XH83_RS36830	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
XH83_RS36850	COG3318	Belongs to the UPF0149 family
XH83_RS36855	COG2433	Pfam Transposase IS66
XH83_RS36865	COG2963	transposase activity
XH83_RS36885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XH83_RS36895	COG0765	amino acid transport
XH83_RS36910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XH83_RS36910	COG4191	Histidine kinase
XH83_RS36915	COG2204	response regulator
XH83_RS36920	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XH83_RS36920	COG1024	Enoyl-CoA hydratase
XH83_RS36925	COG0309	Hydrogenase expression formation protein (HypE)
XH83_RS36930	COG0409	Hydrogenase expression formation protein
XH83_RS36945	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
XH83_RS36950	COG0375	protein maturation
XH83_RS36955	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
XH83_RS36960	COG1773	rubredoxin
XH83_RS36965	COG1773	rubredoxin
XH83_RS36970	COG1773	rubredoxin
XH83_RS36975	COG3118	belongs to the thioredoxin family
XH83_RS36980	COG0298	carbon dioxide binding
XH83_RS36985	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
XH83_RS36990	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
XH83_RS36995	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
XH83_RS37000	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
XH83_RS37020	COG0840	transmembrane signaling receptor activity
XH83_RS37035	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
XH83_RS37045	COG1175	transmembrane transport
XH83_RS37050	COG0395	ABC-type sugar transport system, permease component
XH83_RS37055	COG3842	ATPase activity
XH83_RS37085	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XH83_RS37090	COG3958	Transketolase
XH83_RS37095	COG3959	Transketolase, thiamine diphosphate binding domain
XH83_RS37100	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS37105	COG0583	DNA-binding transcription factor activity
XH83_RS37110	COG1346	cytolysis
XH83_RS37130	COG1053	succinate dehydrogenase
XH83_RS37135	COG5564	TIM-barrel signal transduction protein
XH83_RS37150	COG2204	response regulator
XH83_RS37150	COG5564	TIM-barrel signal transduction protein
XH83_RS37165	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS37170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XH83_RS37175	COG0395	ABC-type sugar transport system, permease component
XH83_RS37180	COG1175	transmembrane transport
XH83_RS37205	COG4451	ribulose bisphosphate carboxylase, small
XH83_RS37210	COG1850	ribulose-bisphosphate carboxylase activity
XH83_RS37225	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XH83_RS37235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XH83_RS37240	COG1126	abc transporter atp-binding protein
XH83_RS37245	COG0765	amino acid transport
XH83_RS37250	COG0765	amino acid transport
XH83_RS37255	COG4221	oxidoreductase activity
XH83_RS37260	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
XH83_RS37270	COG1984	allophanate hydrolase subunit 2
XH83_RS37275	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
XH83_RS37285	COG0511	ligase activity, forming carbon-carbon bonds
XH83_RS37295	COG0436	Aminotransferase
XH83_RS37300	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XH83_RS37315	COG2124	cytochrome p450
XH83_RS37320	COG1846	Transcriptional regulator
XH83_RS37335	COG0375	protein maturation
XH83_RS37420	COG2204	response regulator
XH83_RS37425	COG5001	Diguanylate cyclase
XH83_RS37430	COG2124	cytochrome p450
XH83_RS37450	COG2267	carboxylic ester hydrolase activity
XH83_RS37460	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XH83_RS37525	COG0583	DNA-binding transcription factor activity
XH83_RS37530	COG2188	Transcriptional regulator
XH83_RS37545	COG1012	belongs to the aldehyde dehydrogenase family
XH83_RS37550	COG0028	Belongs to the TPP enzyme family
XH83_RS37555	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
XH83_RS37570	COG1450	Type ii and iii secretion system protein
XH83_RS37600	COG3156	type II secretion system protein K
XH83_RS37625	COG1459	type II secretion system
XH83_RS37630	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XH83_RS37635	COG0583	DNA-binding transcription factor activity
XH83_RS37685	COG2271	Major facilitator Superfamily
XH83_RS37690	COG0583	DNA-binding transcription factor activity
XH83_RS37710	COG1414	Transcriptional regulator
XH83_RS37715	COG4948	Mandelate Racemase Muconate Lactonizing
XH83_RS37720	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XH83_RS37730	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XH83_RS37740	COG0765	amino acid transport
XH83_RS37745	COG0765	amino acid transport
XH83_RS37760	COG0667	Aldo Keto reductase
XH83_RS37780	COG3493	citrate carrier protein
XH83_RS37785	COG0066	3-isopropylmalate dehydratase activity
XH83_RS37800	COG0583	DNA-binding transcription factor activity
XH83_RS37810	COG0702	epimerase
XH83_RS37815	COG0318	PFAM AMP-dependent synthetase and ligase
XH83_RS37820	COG0683	leucine binding
XH83_RS37835	COG1129	ABC transporter
XH83_RS37860	COG3384	dioxygenase
XH83_RS37865	COG2159	amidohydrolase
XH83_RS37880	COG0473	3-isopropylmalate dehydrogenase activity
XH83_RS37880	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XH83_RS37885	COG3706	GGDEF domain
XH83_RS37950	COG0179	Fumarylacetoacetate (FAA) hydrolase
XH83_RS37980	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS37995	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
XH83_RS38015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XH83_RS38020	COG0179	Fumarylacetoacetate (FAA) hydrolase
XH83_RS38030	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XH83_RS38035	COG0066	3-isopropylmalate dehydratase activity
XH83_RS38045	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
XH83_RS38050	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS38055	COG0410	ABC transporter
XH83_RS38075	COG0683	leucine binding
XH83_RS38080	COG0583	DNA-binding transcription factor activity
XH83_RS38095	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XH83_RS38170	COG0464	growth
XH83_RS38185	COG4251	negative regulation of phosphorylation
XH83_RS38185	COG5001	Diguanylate cyclase
XH83_RS38185	COG3706	GGDEF domain
XH83_RS38185	COG2203	Gaf domain
XH83_RS38195	COG1448	Aminotransferase
XH83_RS38200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XH83_RS38205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XH83_RS38220	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XH83_RS38225	COG3483	tryptophan 2,3-dioxygenase activity
XH83_RS38235	COG5001	Diguanylate cyclase
XH83_RS38235	COG3300	MHYT domain
XH83_RS38245	COG2963	transposase activity
XH83_RS38255	COG2433	Pfam Transposase IS66
XH83_RS38260	COG3318	Belongs to the UPF0149 family
XH83_RS38280	COG3620	sequence-specific DNA binding
XH83_RS38285	COG3550	peptidyl-serine autophosphorylation
XH83_RS38325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XH83_RS38340	COG0758	DNA mediated transformation
XH83_RS38345	COG0546	phosphoglycolate phosphatase activity
XH83_RS38360	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XH83_RS38365	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XH83_RS38375	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
XH83_RS38380	COG0644	oxidoreductase
XH83_RS38385	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
XH83_RS38390	COG2086	electron transfer activity
XH83_RS38410	COG5554	nitrogen fixation
XH83_RS38415	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XH83_RS38420	COG0535	radical SAM domain protein
XH83_RS38435	COG5554	nitrogen fixation
XH83_RS38440	COG0316	Belongs to the HesB IscA family
XH83_RS38445	COG3383	formate dehydrogenase (NAD+) activity
XH83_RS38465	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
XH83_RS38470	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
XH83_RS38475	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
XH83_RS38485	COG1028	Short-chain dehydrogenase reductase Sdr
XH83_RS38505	COG4677	pectinesterase activity
XH83_RS38520	COG3604	Transcriptional regulator
XH83_RS38540	COG2192	nodulation
XH83_RS38555	COG2192	nodulation
XH83_RS38560	COG0500	methyltransferase
XH83_RS38570	COG0726	polysaccharide deacetylase
XH83_RS38575	COG3153	acetyltransferase
XH83_RS38585	COG0789	Transcriptional regulator
XH83_RS38605	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XH83_RS38610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XH83_RS38640	COG0275	rRNA processing
XH83_RS38645	COG1301	dicarboxylic acid transport
XH83_RS38650	COG3594	Acyltransferase
XH83_RS38660	COG2771	luxR family
XH83_RS38690	COG4566	intracellular signal transduction
XH83_RS38695	COG4566	intracellular signal transduction
XH83_RS38705	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XH83_RS38730	COG4584	PFAM Integrase catalytic
XH83_RS38735	COG1484	DNA-dependent DNA replication
XH83_RS38740	COG1278	Cold shock
XH83_RS38755	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
XH83_RS38765	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
XH83_RS38790	COG4584	PFAM Integrase catalytic
XH83_RS38830	COG0534	Mate efflux family protein
XH83_RS38835	COG0318	PFAM AMP-dependent synthetase and ligase
XH83_RS38840	COG0604	alcohol dehydrogenase
XH83_RS38855	COG4974	Belongs to the 'phage' integrase family
XH83_RS38865	COG4974	Belongs to the 'phage' integrase family
XH83_RS38875	COG3436	PFAM IS66 Orf2 family protein
XH83_RS38880	COG1484	DNA-dependent DNA replication
XH83_RS38885	COG2390	Transcriptional regulator
XH83_RS38885	COG4584	PFAM Integrase catalytic
XH83_RS38915	COG2801	Transposase and inactivated derivatives
XH83_RS38935	COG4974	Belongs to the 'phage' integrase family
XH83_RS38940	COG0517	IMP dehydrogenase activity
XH83_RS38950	COG4584	PFAM Integrase catalytic
XH83_RS38960	COG3436	PFAM IS66 Orf2 family protein
XH83_RS39010	COG2963	transposase activity
XH83_RS39015	COG3436	PFAM IS66 Orf2 family protein
XH83_RS39025	COG3318	Belongs to the UPF0149 family
XH83_RS39035	COG2801	Transposase and inactivated derivatives
XH83_RS39050	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XH83_RS39055	COG1012	belongs to the aldehyde dehydrogenase family
XH83_RS39060	COG1522	sequence-specific DNA binding
XH83_RS39065	COG0686	Belongs to the AlaDH PNT family
XH83_RS39075	COG1473	amidohydrolase
XH83_RS39080	COG4584	PFAM Integrase catalytic
XH83_RS39110	COG4584	PFAM Integrase catalytic
XH83_RS39115	COG1484	DNA-dependent DNA replication
XH83_RS39140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XH83_RS39150	COG0747	negative chemotaxis
XH83_RS39155	COG2433	Pfam Transposase IS66
XH83_RS39160	COG2433	Pfam Transposase IS66
XH83_RS39165	COG3318	Belongs to the UPF0149 family
XH83_RS39180	COG2843	Capsule synthesis protein
XH83_RS39185	COG1335	isochorismatase
XH83_RS39190	COG2186	Transcriptional regulator
XH83_RS39195	COG0154	amidase activity
XH83_RS39200	COG0318	PFAM AMP-dependent synthetase and ligase
XH83_RS39250	COG4974	Belongs to the 'phage' integrase family
XH83_RS39255	COG0517	IMP dehydrogenase activity
XH83_RS39270	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XH83_RS39305	COG1250	3-hydroxyacyl-CoA dehydrogenase
XH83_RS39310	COG0154	amidase activity
XH83_RS39315	COG2771	luxR family
XH83_RS39335	COG2948	multi-organism process
XH83_RS39350	COG3846	protein secretion by the type IV secretion system
XH83_RS39365	COG3451	type IV secretory pathway VirB4
XH83_RS39375	COG3838	Conjugal transfer protein Trbc
XH83_RS39380	COG4962	Type ii secretion system protein e
XH83_RS39400	COG0739	heme binding
XH83_RS39400	COG0741	lytic transglycosylase activity
XH83_RS39400	COG1196	nuclear chromosome segregation
XH83_RS39405	COG0681	Belongs to the peptidase S26 family
XH83_RS39440	COG1476	TRANSCRIPTIONal
XH83_RS39450	COG5489	Protein of unknown function (DUF736)
XH83_RS39460	COG5489	Protein of unknown function (DUF736)
XH83_RS39485	COG0070	glutamate synthase
XH83_RS39485	COG0069	glutamate synthase activity
XH83_RS39485	COG0067	glutamate synthase
XH83_RS39495	COG0347	Belongs to the P(II) protein family
XH83_RS39500	COG2835	tetraacyldisaccharide 4'-kinase activity
XH83_RS39505	COG3328	transposase activity