locus-tag	class	description
HAU86_RS00040	COG1215	transferase activity, transferring glycosyl groups
HAU86_RS00060	COG0655	NAD(P)H dehydrogenase (quinone) activity
HAU86_RS00065	COG1741	Belongs to the pirin family
HAU86_RS00070	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS00075	COG0583	DNA-binding transcription factor activity
HAU86_RS00095	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HAU86_RS00105	COG1733	regulation of RNA biosynthetic process
HAU86_RS00110	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS00120	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HAU86_RS00145	COG3474	cytochrome
HAU86_RS00150	COG0277	FAD linked oxidase domain protein
HAU86_RS00155	COG0277	FAD linked oxidase domain protein
HAU86_RS00160	COG0247	lactate metabolic process
HAU86_RS00175	COG4178	(ABC) transporter
HAU86_RS00180	COG1620	l-lactate permease
HAU86_RS00195	COG0459	protein refolding
HAU86_RS00200	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HAU86_RS00215	COG1388	LysM domain
HAU86_RS00215	COG1376	ErfK ybiS ycfS ynhG family protein
HAU86_RS00220	COG3416	Protein conserved in bacteria
HAU86_RS00230	COG0463	Glycosyl transferase, family 2
HAU86_RS00235	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HAU86_RS00240	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HAU86_RS00275	COG0312	modulator of DNA gyrase
HAU86_RS00295	COG1519	Transferase
HAU86_RS00300	COG1663	tetraacyldisaccharide 4'-kinase activity
HAU86_RS00320	COG1570	exodeoxyribonuclease VII activity
HAU86_RS00365	COG0151	Belongs to the GarS family
HAU86_RS00370	COG0596	Alpha beta hydrolase
HAU86_RS00375	COG0590	tRNA wobble adenosine to inosine editing
HAU86_RS00380	COG1187	pseudouridine synthase activity
HAU86_RS00385	COG0742	ribosomal rna small subunit methyltransferase
HAU86_RS00390	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HAU86_RS00425	COG0612	Peptidase, M16
HAU86_RS00430	COG0612	Peptidase, M16
HAU86_RS00440	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HAU86_RS00445	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HAU86_RS00450	COG0196	riboflavin kinase activity
HAU86_RS00455	COG0745	RESPONSE REGULATOR receiver
HAU86_RS00465	COG2771	luxR family
HAU86_RS00465	COG2200	EAL domain
HAU86_RS00480	COG1295	ribonuclease BN
HAU86_RS00490	COG2890	protein-(glutamine-N5) methyltransferase activity
HAU86_RS00495	COG0314	molybdopterin synthase activity
HAU86_RS00505	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HAU86_RS00510	COG0322	excinuclease ABC activity
HAU86_RS00515	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HAU86_RS00520	COG1278	Cold shock
HAU86_RS00525	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HAU86_RS00555	COG0745	RESPONSE REGULATOR receiver
HAU86_RS00560	COG1846	Transcriptional regulator
HAU86_RS00575	COG0124	histidyl-tRNA synthetase
HAU86_RS00580	COG1942	4-Oxalocrotonate Tautomerase
HAU86_RS00595	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HAU86_RS00605	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HAU86_RS00610	COG1181	Belongs to the D-alanine--D-alanine ligase family
HAU86_RS00620	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HAU86_RS00640	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HAU86_RS00655	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HAU86_RS00660	COG0193	aminoacyl-tRNA hydrolase activity
HAU86_RS00665	COG0012	GTP binding
HAU86_RS00675	COG2030	dehydratase
HAU86_RS00725	COG0556	nucleotide-excision repair
HAU86_RS00740	COG0583	DNA-binding transcription factor activity
HAU86_RS00780	COG0667	Aldo Keto reductase
HAU86_RS00805	COG0625	glutathione transferase activity
HAU86_RS00810	COG0436	Aminotransferase
HAU86_RS00820	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HAU86_RS00830	COG0659	secondary active sulfate transmembrane transporter activity
HAU86_RS00835	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HAU86_RS00855	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HAU86_RS00860	COG2223	nitrite transmembrane transporter activity
HAU86_RS00875	COG0625	glutathione transferase activity
HAU86_RS00895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HAU86_RS00900	COG0183	Belongs to the thiolase family
HAU86_RS00915	COG2205	protein histidine kinase activity
HAU86_RS00940	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HAU86_RS00955	COG2301	Belongs to the HpcH HpaI aldolase family
HAU86_RS00985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HAU86_RS00990	COG0583	DNA-binding transcription factor activity
HAU86_RS00995	COG0492	ferredoxin-NADP+ reductase activity
HAU86_RS01000	COG1522	sequence-specific DNA binding
HAU86_RS01005	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HAU86_RS01010	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HAU86_RS01015	COG2814	Major facilitator Superfamily
HAU86_RS01050	COG0505	Belongs to the CarA family
HAU86_RS01065	COG0596	Alpha beta hydrolase
HAU86_RS01070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HAU86_RS01125	COG0640	Transcriptional regulator
HAU86_RS01135	COG1280	lysine exporter protein (LysE YggA)
HAU86_RS01150	COG2105	PFAM AIG2 family protein
HAU86_RS01160	COG0358	DNA primase activity
HAU86_RS01165	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAU86_RS01200	COG1280	lysine exporter protein (LysE YggA)
HAU86_RS01205	COG3706	GGDEF domain
HAU86_RS01220	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAU86_RS01225	COG0564	pseudouridine synthase activity
HAU86_RS01295	COG2814	Major facilitator Superfamily
HAU86_RS01315	COG0583	DNA-binding transcription factor activity
HAU86_RS01360	COG1132	(ABC) transporter
HAU86_RS01380	COG3064	Membrane
HAU86_RS01460	COG1136	(ABC) transporter
HAU86_RS01465	COG0210	DNA helicase
HAU86_RS01485	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HAU86_RS01525	COG1176	ABC-type spermidine putrescine transport system, permease component I
HAU86_RS01530	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HAU86_RS01535	COG3842	ATPase activity
HAU86_RS01550	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HAU86_RS01555	COG3284	Transcriptional regulator
HAU86_RS01570	COG3734	2-keto-3-deoxy-galactonokinase
HAU86_RS01575	COG0800	Aldolase
HAU86_RS01580	COG0028	Belongs to the TPP enzyme family
HAU86_RS01620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HAU86_RS01630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HAU86_RS01645	COG1960	acyl-CoA dehydrogenase activity
HAU86_RS01650	COG1960	acyl-CoA dehydrogenase activity
HAU86_RS01655	COG1024	Enoyl-CoA hydratase
HAU86_RS01660	COG1704	LemA family
HAU86_RS01665	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HAU86_RS01690	COG0625	glutathione transferase activity
HAU86_RS01705	COG0506	proline dehydrogenase activity
HAU86_RS01705	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HAU86_RS01705	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HAU86_RS01715	COG1278	Cold shock
HAU86_RS01740	COG3768	UPF0283 membrane protein
HAU86_RS01745	COG3106	COG3106 Predicted ATPase
HAU86_RS01750	COG1272	protein, Hemolysin III
HAU86_RS01755	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS01765	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS01775	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HAU86_RS01785	COG1960	acyl-CoA dehydrogenase activity
HAU86_RS01790	COG0583	DNA-binding transcription factor activity
HAU86_RS01810	COG0501	Belongs to the peptidase M48B family
HAU86_RS01820	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HAU86_RS01835	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HAU86_RS01845	COG1376	ErfK ybiS ycfS ynhG family protein
HAU86_RS01850	COG0028	Belongs to the TPP enzyme family
HAU86_RS01880	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HAU86_RS01890	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS01925	COG0784	Response regulator, receiver
HAU86_RS01925	COG2198	Histidine kinase
HAU86_RS01925	COG0643	Histidine kinase
HAU86_RS01930	COG0835	chemotaxis
HAU86_RS01935	COG0784	Response regulator, receiver
HAU86_RS01935	COG2198	Histidine kinase
HAU86_RS01935	COG0643	Histidine kinase
HAU86_RS01940	COG2201	protein-glutamate methylesterase activity
HAU86_RS01950	COG0754	glutathionylspermidine amidase activity
HAU86_RS01960	COG3766	membrane
HAU86_RS01980	COG1595	DNA-templated transcription, initiation
HAU86_RS02005	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HAU86_RS02050	COG1309	transcriptional regulator
HAU86_RS02055	COG2080	2 iron, 2 sulfur cluster binding
HAU86_RS02060	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HAU86_RS02065	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HAU86_RS02085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HAU86_RS02095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HAU86_RS02105	COG1126	abc transporter atp-binding protein
HAU86_RS02110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HAU86_RS02115	COG0405	Gamma-glutamyltransferase
HAU86_RS02120	COG1024	Enoyl-CoA hydratase
HAU86_RS02215	COG0683	leucine binding
HAU86_RS02220	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HAU86_RS02235	COG2226	methyltransferase
HAU86_RS02320	COG1129	ABC transporter
HAU86_RS02330	COG1172	Belongs to the binding-protein-dependent transport system permease family
HAU86_RS02335	COG1879	ABC-type sugar transport system periplasmic component
HAU86_RS02340	COG1172	Belongs to the binding-protein-dependent transport system permease family
HAU86_RS02360	COG0366	Alpha amylase catalytic
HAU86_RS02365	COG0438	transferase activity, transferring glycosyl groups
HAU86_RS02420	COG0303	'Molybdopterin
HAU86_RS02430	COG0746	molybdenum cofactor guanylyltransferase activity
HAU86_RS02440	COG1763	Mo-molybdopterin cofactor biosynthetic process
HAU86_RS02460	COG5002	protein histidine kinase activity
HAU86_RS02465	COG2223	nitrite transmembrane transporter activity
HAU86_RS02480	COG3383	formate dehydrogenase (NAD+) activity
HAU86_RS02485	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HAU86_RS02505	COG2084	Dehydrogenase
HAU86_RS02510	COG1414	Transcriptional regulator
HAU86_RS02520	COG1053	succinate dehydrogenase
HAU86_RS02520	COG0431	NADPH-dependent FMN reductase
HAU86_RS02520	COG3976	FMN-binding domain protein
HAU86_RS02545	COG5002	protein histidine kinase activity
HAU86_RS02545	COG5001	Diguanylate cyclase
HAU86_RS02545	COG3447	MASE1 domain protein
HAU86_RS02550	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HAU86_RS02555	COG0583	DNA-binding transcription factor activity
HAU86_RS02560	COG3485	protocatechuate 3,4-dioxygenase
HAU86_RS02565	COG3485	protocatechuate 3,4-dioxygenase
HAU86_RS02600	COG0745	RESPONSE REGULATOR receiver
HAU86_RS02605	COG0643	Histidine kinase
HAU86_RS02605	COG2198	Histidine kinase
HAU86_RS02610	COG0835	chemotaxis
HAU86_RS02615	COG0840	transmembrane signaling receptor activity
HAU86_RS02625	COG0840	transmembrane signaling receptor activity
HAU86_RS02635	COG2201	protein-glutamate methylesterase activity
HAU86_RS02715	COG1596	polysaccharide export
HAU86_RS02730	COG3206	protein involved in exopolysaccharide biosynthesis
HAU86_RS02730	COG0489	protein tyrosine kinase activity
HAU86_RS02740	COG0438	transferase activity, transferring glycosyl groups
HAU86_RS02770	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HAU86_RS02870	COG2801	Transposase and inactivated derivatives
HAU86_RS03045	COG1091	dTDP-4-dehydrorhamnose reductase activity
HAU86_RS03220	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HAU86_RS03240	COG0438	transferase activity, transferring glycosyl groups
HAU86_RS03250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HAU86_RS03270	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HAU86_RS03280	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HAU86_RS03290	COG3206	protein involved in exopolysaccharide biosynthesis
HAU86_RS03290	COG0489	protein tyrosine kinase activity
HAU86_RS03300	COG2755	lipolytic protein G-D-S-L family
HAU86_RS03300	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HAU86_RS03315	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HAU86_RS03440	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HAU86_RS03455	COG0489	protein tyrosine kinase activity
HAU86_RS03465	COG0367	asparagine synthase
HAU86_RS03470	COG1960	acyl-CoA dehydrogenase activity
HAU86_RS03510	COG1216	Glycosyl transferase, family 2
HAU86_RS03520	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HAU86_RS03565	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
HAU86_RS03570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAU86_RS03575	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HAU86_RS03605	COG3300	MHYT domain
HAU86_RS03605	COG5001	Diguanylate cyclase
HAU86_RS03635	COG0181	hydroxymethylbilane synthase activity
HAU86_RS03640	COG4566	intracellular signal transduction
HAU86_RS03645	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HAU86_RS03655	COG2203	Gaf domain
HAU86_RS03655	COG4251	negative regulation of phosphorylation
HAU86_RS03655	COG5001	Diguanylate cyclase
HAU86_RS03655	COG3706	GGDEF domain
HAU86_RS03660	COG2900	Belongs to the SlyX family
HAU86_RS03670	COG0405	Gamma-glutamyltransferase
HAU86_RS03680	COG3237	CsbD-like
HAU86_RS03720	COG3214	Protein conserved in bacteria
HAU86_RS03745	COG1309	transcriptional regulator
HAU86_RS03770	COG1607	acyl-coa hydrolase
HAU86_RS03790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HAU86_RS03795	COG1349	DNA-binding transcription factor activity
HAU86_RS03815	COG3842	ATPase activity
HAU86_RS03820	COG3842	ATPase activity
HAU86_RS03830	COG0395	ABC-type sugar transport system, permease component
HAU86_RS03845	COG1902	pentaerythritol trinitrate reductase activity
HAU86_RS03870	COG0501	Belongs to the peptidase M48B family
HAU86_RS03920	COG0494	nUDIX hydrolase
HAU86_RS03940	COG4771	TonB-dependent receptor
HAU86_RS03965	COG0714	Associated with various cellular activities
HAU86_RS03985	COG0617	tRNA 3'-terminal CCA addition
HAU86_RS04000	COG2943	transferase activity, transferring hexosyl groups
HAU86_RS04005	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
HAU86_RS04025	COG0408	coproporphyrinogen oxidase activity
HAU86_RS04030	COG0602	queuosine metabolic process
HAU86_RS04035	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HAU86_RS04040	COG0723	plastoquinol--plastocyanin reductase activity
HAU86_RS04045	COG2857	Cytochrome c1
HAU86_RS04045	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HAU86_RS04070	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HAU86_RS04095	COG1704	LemA family
HAU86_RS04105	COG1196	nuclear chromosome segregation
HAU86_RS04110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HAU86_RS04120	COG1194	a g-specific adenine glycosylase
HAU86_RS04125	COG3706	GGDEF domain
HAU86_RS04140	COG0625	glutathione transferase activity
HAU86_RS04165	COG4251	negative regulation of phosphorylation
HAU86_RS04170	COG0840	transmembrane signaling receptor activity
HAU86_RS04175	COG0625	glutathione transferase activity
HAU86_RS04180	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HAU86_RS04190	COG2321	neutral zinc metallopeptidase
HAU86_RS04195	COG0521	Mo-molybdopterin cofactor biosynthetic process
HAU86_RS04200	COG1846	Transcriptional regulator
HAU86_RS04200	COG0456	acetyltransferase
HAU86_RS04215	COG0574	Belongs to the PEP-utilizing enzyme family
HAU86_RS04215	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HAU86_RS04225	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HAU86_RS04230	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
HAU86_RS04245	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HAU86_RS04255	COG1573	uracil-dna glycosylase
HAU86_RS04270	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HAU86_RS04280	COG1280	lysine exporter protein (LysE YggA)
HAU86_RS04285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HAU86_RS04295	COG0142	geranyltranstransferase activity
HAU86_RS04305	COG2813	Specifically methylates the guanine in position
HAU86_RS04320	COG0752	glycyl-tRNA synthetase alpha subunit
HAU86_RS04325	COG0751	glycine-tRNA ligase activity
HAU86_RS04340	COG0574	Belongs to the PEP-utilizing enzyme family
HAU86_RS04340	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HAU86_RS04345	COG3773	Cell wall hydrolase
HAU86_RS04345	COG3409	Peptidoglycan-binding domain 1 protein
HAU86_RS04355	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HAU86_RS04360	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HAU86_RS04375	COG0604	alcohol dehydrogenase
HAU86_RS04415	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
HAU86_RS04420	COG0519	Catalyzes the synthesis of GMP from XMP
HAU86_RS04425	COG0354	folic acid binding
HAU86_RS04430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HAU86_RS04435	COG2897	thiosulfate sulfurtransferase activity
HAU86_RS04460	COG2135	peptidase activity
HAU86_RS04475	COG0494	nUDIX hydrolase
HAU86_RS04485	COG0277	FAD linked oxidase domain protein
HAU86_RS04490	COG0009	L-threonylcarbamoyladenylate synthase
HAU86_RS04530	COG2864	formate dehydrogenase
HAU86_RS04535	COG0437	4 iron, 4 sulfur cluster binding
HAU86_RS04540	COG0243	molybdopterin cofactor binding
HAU86_RS04540	COG3383	formate dehydrogenase (NAD+) activity
HAU86_RS04555	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
HAU86_RS04575	COG1309	transcriptional regulator
HAU86_RS04580	COG2814	Major facilitator Superfamily
HAU86_RS04600	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HAU86_RS04620	COG1850	ribulose-bisphosphate carboxylase activity
HAU86_RS04625	COG4451	ribulose bisphosphate carboxylase, small
HAU86_RS04645	COG5001	Diguanylate cyclase
HAU86_RS04645	COG3300	MHYT domain
HAU86_RS04655	COG0589	response to stress
HAU86_RS04685	COG0693	protein deglycase activity
HAU86_RS04745	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS04765	COG3415	Transposase
HAU86_RS04765	COG2801	Transposase and inactivated derivatives
HAU86_RS04795	COG0656	L-ascorbic acid biosynthetic process
HAU86_RS04815	COG3384	dioxygenase
HAU86_RS04820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HAU86_RS04830	COG0475	glutathione-regulated potassium exporter activity
HAU86_RS04830	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HAU86_RS04840	COG1960	acyl-CoA dehydrogenase activity
HAU86_RS04855	COG0318	PFAM AMP-dependent synthetase and ligase
HAU86_RS04870	COG0598	Magnesium transport protein CorA
HAU86_RS04880	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS04885	COG0259	pyridoxamine-phosphate oxidase activity
HAU86_RS04910	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HAU86_RS04920	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HAU86_RS04935	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HAU86_RS04940	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HAU86_RS04970	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HAU86_RS04975	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
HAU86_RS04985	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HAU86_RS04990	COG1722	exodeoxyribonuclease VII activity
HAU86_RS04995	COG0123	including yeast histone deacetylase and acetoin utilization protein
HAU86_RS05000	COG0737	Belongs to the 5'-nucleotidase family
HAU86_RS05000	COG1525	nuclease
HAU86_RS05000	COG4085	toxin activity
HAU86_RS05015	COG1960	acyl-CoA dehydrogenase activity
HAU86_RS05030	COG0071	Belongs to the small heat shock protein (HSP20) family
HAU86_RS05050	COG0346	lactoylglutathione lyase activity
HAU86_RS05055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HAU86_RS05075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HAU86_RS05085	COG1473	amidohydrolase
HAU86_RS05090	COG4948	Mandelate Racemase Muconate Lactonizing
HAU86_RS05120	COG0741	lytic transglycosylase activity
HAU86_RS05155	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HAU86_RS05165	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HAU86_RS05185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HAU86_RS05205	COG1335	isochorismatase
HAU86_RS05215	COG3258	Cytochrome c
HAU86_RS05235	COG0446	pyridine nucleotide-disulphide oxidoreductase
HAU86_RS05240	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HAU86_RS05240	COG2010	Cytochrome c
HAU86_RS05250	COG1032	radical SAM domain protein
HAU86_RS05260	COG2814	Major facilitator Superfamily
HAU86_RS05265	COG0473	3-isopropylmalate dehydrogenase activity
HAU86_RS05320	COG4106	trans-aconitate 2-methyltransferase activity
HAU86_RS05335	COG5001	Diguanylate cyclase
HAU86_RS05335	COG5002	protein histidine kinase activity
HAU86_RS05340	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HAU86_RS05345	COG0438	transferase activity, transferring glycosyl groups
HAU86_RS05350	COG1132	(ABC) transporter
HAU86_RS05370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HAU86_RS05380	COG4566	intracellular signal transduction
HAU86_RS05385	COG4191	Histidine kinase
HAU86_RS05395	COG0516	GMP reductase activity
HAU86_RS05395	COG0517	IMP dehydrogenase activity
HAU86_RS05400	COG3278	Belongs to the heme-copper respiratory oxidase family
HAU86_RS05415	COG2010	Cytochrome c
HAU86_RS05430	COG2217	Heavy metal translocating P-type atpase
HAU86_RS05460	COG0583	DNA-binding transcription factor activity
HAU86_RS05465	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS05475	COG0297	glycogen (starch) synthase activity
HAU86_RS05480	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HAU86_RS05485	COG0747	negative chemotaxis
HAU86_RS05495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HAU86_RS05500	COG0444	Belongs to the ABC transporter superfamily
HAU86_RS05515	COG0473	3-isopropylmalate dehydrogenase activity
HAU86_RS05525	COG1024	Enoyl-CoA hydratase
HAU86_RS05530	COG1396	sequence-specific DNA binding
HAU86_RS05545	COG0785	Cytochrome C biogenesis protein
HAU86_RS05565	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HAU86_RS05565	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HAU86_RS05575	COG3485	protocatechuate 3,4-dioxygenase
HAU86_RS05580	COG0583	DNA-binding transcription factor activity
HAU86_RS05600	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HAU86_RS05605	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HAU86_RS05610	COG1116	anion transmembrane transporter activity
HAU86_RS05615	COG2223	nitrite transmembrane transporter activity
HAU86_RS05620	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HAU86_RS05620	COG1017	nitric oxide dioxygenase activity
HAU86_RS05625	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HAU86_RS05630	COG0243	molybdopterin cofactor binding
HAU86_RS05640	COG0656	L-ascorbic acid biosynthetic process
HAU86_RS05645	COG0697	spore germination
HAU86_RS05650	COG1063	alcohol dehydrogenase
HAU86_RS05655	COG1522	sequence-specific DNA binding
HAU86_RS05660	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HAU86_RS05670	COG3386	PFAM SMP-30 Gluconolaconase
HAU86_RS05675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HAU86_RS05680	COG2020	methyltransferase activity
HAU86_RS05700	COG0457	Tetratricopeptide repeat
HAU86_RS05700	COG3710	Transcriptional regulator
HAU86_RS05715	COG0129	dihydroxy-acid dehydratase activity
HAU86_RS05730	COG1024	Enoyl-CoA hydratase
HAU86_RS05740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HAU86_RS05745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HAU86_RS05755	COG1309	transcriptional regulator
HAU86_RS05760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HAU86_RS05780	COG0673	inositol 2-dehydrogenase activity
HAU86_RS05795	COG2124	cytochrome p450
HAU86_RS05805	COG0028	Belongs to the TPP enzyme family
HAU86_RS05805	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
HAU86_RS05815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAU86_RS05820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAU86_RS05830	COG2204	response regulator
HAU86_RS05835	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HAU86_RS05850	COG0601	transmembrane transport
HAU86_RS05855	COG0747	negative chemotaxis
HAU86_RS05860	COG4608	Belongs to the ABC transporter superfamily
HAU86_RS05865	COG0444	Belongs to the ABC transporter superfamily
HAU86_RS05880	COG4608	Belongs to the ABC transporter superfamily
HAU86_RS05885	COG0444	Belongs to the ABC transporter superfamily
HAU86_RS05900	COG0747	negative chemotaxis
HAU86_RS05920	COG2267	carboxylic ester hydrolase activity
HAU86_RS05925	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HAU86_RS05925	COG2124	cytochrome p450
HAU86_RS05935	COG0596	Alpha beta hydrolase
HAU86_RS05960	COG2733	membrane
HAU86_RS05965	COG0596	Alpha beta hydrolase
HAU86_RS05970	COG3327	negative regulation of DNA-templated transcription, initiation
HAU86_RS05975	COG3396	Phenylacetate-CoA oxygenase
HAU86_RS05980	COG3460	Phenylacetate-CoA oxygenase
HAU86_RS05985	COG3396	Phenylacetate-CoA oxygenase
HAU86_RS05990	COG2151	metal-sulfur cluster biosynthetic enzyme
HAU86_RS05995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HAU86_RS06000	COG2050	protein possibly involved in aromatic compounds catabolism
HAU86_RS06025	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HAU86_RS06030	COG0477	Major facilitator Superfamily
HAU86_RS06055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HAU86_RS06060	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HAU86_RS06070	COG4597	amino acid ABC transporter
HAU86_RS06075	COG0765	amino acid transport
HAU86_RS06085	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS06090	COG0473	3-isopropylmalate dehydrogenase activity
HAU86_RS06095	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HAU86_RS06100	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HAU86_RS06110	COG0583	DNA-binding transcription factor activity
HAU86_RS06115	COG4336	lyase activity
HAU86_RS06125	COG0559	Belongs to the binding-protein-dependent transport system permease family
HAU86_RS06150	COG0235	Class ii aldolase
HAU86_RS06155	COG2084	Dehydrogenase
HAU86_RS06160	COG3622	Belongs to the hyi family
HAU86_RS06165	COG3395	kinase activity
HAU86_RS06170	COG0840	transmembrane signaling receptor activity
HAU86_RS06180	COG0840	transmembrane signaling receptor activity
HAU86_RS06190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAU86_RS06200	COG2070	2-Nitropropane dioxygenase
HAU86_RS06205	COG0625	glutathione transferase activity
HAU86_RS06215	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HAU86_RS06230	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS06235	COG1024	Enoyl-CoA hydratase
HAU86_RS06250	COG1024	Enoyl-CoA hydratase
HAU86_RS06255	COG1960	acyl-CoA dehydrogenase activity
HAU86_RS06270	COG1024	Enoyl-CoA hydratase
HAU86_RS06280	COG1024	Enoyl-CoA hydratase
HAU86_RS06305	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HAU86_RS06310	COG3386	PFAM SMP-30 Gluconolaconase
HAU86_RS06315	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS06345	COG3145	DNA-N1-methyladenine dioxygenase activity
HAU86_RS06355	COG0028	Belongs to the TPP enzyme family
HAU86_RS06360	COG0179	Fumarylacetoacetate (FAA) hydrolase
HAU86_RS06370	COG1012	belongs to the aldehyde dehydrogenase family
HAU86_RS06380	COG3971	2-oxopent-4-enoate hydratase activity
HAU86_RS06385	COG1846	Transcriptional regulator
HAU86_RS06390	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HAU86_RS06400	COG2721	sulfolactate sulfo-lyase activity
HAU86_RS06430	COG1335	isochorismatase
HAU86_RS06435	COG1741	Belongs to the pirin family
HAU86_RS06440	COG0583	DNA-binding transcription factor activity
HAU86_RS06455	COG0395	ABC-type sugar transport system, permease component
HAU86_RS06460	COG1175	transmembrane transport
HAU86_RS06465	COG3842	ATPase activity
HAU86_RS06505	COG2267	carboxylic ester hydrolase activity
HAU86_RS06515	COG4303	Ethanolamine ammonia lyase large subunit
HAU86_RS06525	COG4302	ethanolamine ammonia-lyase activity
HAU86_RS06545	COG1562	ergosterol biosynthetic process
HAU86_RS06550	COG1562	ergosterol biosynthetic process
HAU86_RS06555	COG1233	COG1233 Phytoene dehydrogenase and related
HAU86_RS06560	COG1657	PFAM Prenyltransferase squalene oxidase
HAU86_RS06585	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HAU86_RS06615	COG1595	DNA-templated transcription, initiation
HAU86_RS06640	COG1473	amidohydrolase
HAU86_RS06645	COG0306	phosphate transporter
HAU86_RS06650	COG1573	uracil-dna glycosylase
HAU86_RS06670	COG0587	DNA-directed DNA polymerase activity
HAU86_RS06675	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS06685	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HAU86_RS06715	COG1024	Enoyl-CoA hydratase
HAU86_RS06780	COG1703	isobutyryl-CoA mutase activity
HAU86_RS06825	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HAU86_RS06835	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HAU86_RS06850	COG0433	COG0433 Predicted ATPase
HAU86_RS06880	COG4957	zinc ion binding
HAU86_RS06885	COG2166	iron-sulfur cluster assembly
HAU86_RS06895	COG2205	protein histidine kinase activity
HAU86_RS06950	COG0798	PFAM Bile acid sodium symporter
HAU86_RS07030	COG2983	Belongs to the UPF0260 family
HAU86_RS07035	COG2814	Major facilitator Superfamily
HAU86_RS07045	COG0028	Belongs to the TPP enzyme family
HAU86_RS07070	COG4977	sequence-specific DNA binding
HAU86_RS07070	COG1917	Cupin 2, conserved barrel domain protein
HAU86_RS07095	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HAU86_RS07100	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HAU86_RS07105	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HAU86_RS07120	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HAU86_RS07130	COG0745	RESPONSE REGULATOR receiver
HAU86_RS07150	COG4235	cytochrome complex assembly
HAU86_RS07155	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
HAU86_RS07160	COG1138	Cytochrome C-type biogenesis protein
HAU86_RS07165	COG3088	subunit of a heme lyase
HAU86_RS07180	COG0745	RESPONSE REGULATOR receiver
HAU86_RS07185	COG2205	protein histidine kinase activity
HAU86_RS07190	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HAU86_RS07200	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HAU86_RS07205	COG3383	formate dehydrogenase (NAD+) activity
HAU86_RS07220	COG0583	DNA-binding transcription factor activity
HAU86_RS07225	COG2205	protein histidine kinase activity
HAU86_RS07225	COG2202	Pas domain
HAU86_RS07230	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HAU86_RS07235	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS07235	COG0604	alcohol dehydrogenase
HAU86_RS07235	COG3321	synthase
HAU86_RS07265	COG0179	Fumarylacetoacetate (FAA) hydrolase
HAU86_RS07270	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HAU86_RS07310	COG0443	Heat shock 70 kDa protein
HAU86_RS07335	COG1278	Cold shock
HAU86_RS07355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HAU86_RS07365	COG1802	Transcriptional regulator
HAU86_RS07375	COG1414	Transcriptional regulator
HAU86_RS07400	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HAU86_RS07405	COG3960	tartronate-semialdehyde synthase activity
HAU86_RS07410	COG3622	Belongs to the hyi family
HAU86_RS07415	COG2084	Dehydrogenase
HAU86_RS07440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HAU86_RS07450	COG1247	-acetyltransferase
HAU86_RS07455	COG1982	Orn Lys Arg decarboxylase major
HAU86_RS07460	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HAU86_RS07465	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HAU86_RS07470	COG2080	2 iron, 2 sulfur cluster binding
HAU86_RS07480	COG2072	flavoprotein involved in K transport
HAU86_RS07485	COG1309	transcriptional regulator
HAU86_RS07490	COG0318	PFAM AMP-dependent synthetase and ligase
HAU86_RS07515	COG0410	ABC transporter
HAU86_RS07525	COG2855	membrane
HAU86_RS07535	COG1879	ABC-type sugar transport system periplasmic component
HAU86_RS07540	COG1129	ABC transporter
HAU86_RS07545	COG1172	Belongs to the binding-protein-dependent transport system permease family
HAU86_RS07550	COG1172	Belongs to the binding-protein-dependent transport system permease family
HAU86_RS07570	COG3386	PFAM SMP-30 Gluconolaconase
HAU86_RS07575	COG4213	ABC transporter substrate-binding protein
HAU86_RS07585	COG4214	carbohydrate transport
HAU86_RS07595	COG1845	cytochrome c oxidase, subunit III
HAU86_RS07610	COG3256	nitric oxide reductase
HAU86_RS07615	COG0714	Associated with various cellular activities
HAU86_RS07635	COG0154	amidase activity
HAU86_RS07645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HAU86_RS07655	COG4608	Belongs to the ABC transporter superfamily
HAU86_RS07660	COG0747	negative chemotaxis
HAU86_RS07670	COG0400	carboxylic ester hydrolase activity
HAU86_RS07675	COG0346	lactoylglutathione lyase activity
HAU86_RS07680	COG0583	DNA-binding transcription factor activity
HAU86_RS07690	COG0778	Nitroreductase
HAU86_RS07695	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HAU86_RS07705	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HAU86_RS07715	COG1492	cobalamin metabolic process
HAU86_RS07760	COG2099	Precorrin-6x reductase
HAU86_RS07775	COG2875	Belongs to the precorrin methyltransferase family
HAU86_RS07780	COG1797	cobyrinic acid a,c-diamide synthase activity
HAU86_RS07785	COG1648	precorrin-2 dehydrogenase activity
HAU86_RS07785	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HAU86_RS07800	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HAU86_RS07830	COG2207	Transcriptional regulator
HAU86_RS07855	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HAU86_RS07875	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS07880	COG2072	flavoprotein involved in K transport
HAU86_RS07885	COG0747	negative chemotaxis
HAU86_RS07890	COG0601	transmembrane transport
HAU86_RS07905	COG0747	negative chemotaxis
HAU86_RS07910	COG0601	transmembrane transport
HAU86_RS07915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HAU86_RS07920	COG0444	Belongs to the ABC transporter superfamily
HAU86_RS07925	COG4608	Belongs to the ABC transporter superfamily
HAU86_RS07935	COG1879	ABC-type sugar transport system periplasmic component
HAU86_RS07940	COG1172	Belongs to the binding-protein-dependent transport system permease family
HAU86_RS07945	COG1172	Belongs to the binding-protein-dependent transport system permease family
HAU86_RS07950	COG1129	ABC transporter
HAU86_RS07955	COG0277	FAD linked oxidase domain protein
HAU86_RS07960	COG3485	protocatechuate 3,4-dioxygenase
HAU86_RS07970	COG0402	S-adenosylhomocysteine deaminase activity
HAU86_RS08005	COG0445	tRNA wobble uridine modification
HAU86_RS08035	COG0559	Belongs to the binding-protein-dependent transport system permease family
HAU86_RS08060	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS08075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HAU86_RS08080	COG4566	intracellular signal transduction
HAU86_RS08085	COG4566	intracellular signal transduction
HAU86_RS08100	COG2985	domain, Protein
HAU86_RS08115	COG1982	Orn Lys Arg decarboxylase major
HAU86_RS08150	COG4191	Histidine kinase
HAU86_RS08155	COG3064	Membrane
HAU86_RS08175	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HAU86_RS08195	COG0640	Transcriptional regulator
HAU86_RS08205	COG0785	Cytochrome C biogenesis protein
HAU86_RS08240	COG0737	Belongs to the 5'-nucleotidase family
HAU86_RS08245	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HAU86_RS08270	COG2391	methyltransferase activity
HAU86_RS08275	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS08285	COG1653	transport
HAU86_RS08300	COG1063	alcohol dehydrogenase
HAU86_RS08305	COG3842	ATPase activity
HAU86_RS08310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HAU86_RS08315	COG3684	Belongs to the aldolase LacD family
HAU86_RS08325	COG1116	anion transmembrane transporter activity
HAU86_RS08330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HAU86_RS08335	COG4521	taurine ABC transporter
HAU86_RS08340	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HAU86_RS08355	COG1053	succinate dehydrogenase
HAU86_RS08385	COG3842	ATPase activity
HAU86_RS08410	COG0583	DNA-binding transcription factor activity
HAU86_RS08415	COG0154	amidase activity
HAU86_RS08425	COG2351	hydroxyisourate hydrolase activity
HAU86_RS08435	COG1176	ABC-type spermidine putrescine transport system, permease component I
HAU86_RS08440	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HAU86_RS08445	COG3842	ATPase activity
HAU86_RS08460	COG1802	Transcriptional regulator
HAU86_RS08470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HAU86_RS08475	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HAU86_RS08505	COG2205	protein histidine kinase activity
HAU86_RS08510	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAU86_RS08515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAU86_RS08520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAU86_RS08545	COG3038	cytochrome b561
HAU86_RS08560	COG2140	Oxalate decarboxylase
HAU86_RS08565	COG0243	molybdopterin cofactor binding
HAU86_RS08570	COG4191	Histidine kinase
HAU86_RS08580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAU86_RS08605	COG3052	prosthetic group binding
HAU86_RS08625	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
HAU86_RS08645	COG4566	intracellular signal transduction
HAU86_RS08650	COG4191	Histidine kinase
HAU86_RS08675	COG2205	protein histidine kinase activity
HAU86_RS08675	COG2202	Pas domain
HAU86_RS08680	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HAU86_RS08685	COG2084	Dehydrogenase
HAU86_RS08700	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
HAU86_RS08705	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
HAU86_RS08715	COG0745	RESPONSE REGULATOR receiver
HAU86_RS08720	COG5002	protein histidine kinase activity
HAU86_RS08725	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HAU86_RS08735	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HAU86_RS08745	COG0546	phosphoglycolate phosphatase activity
HAU86_RS08750	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HAU86_RS08790	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HAU86_RS08795	COG0121	glutamine amidotransferase
HAU86_RS08810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HAU86_RS08810	COG1017	nitric oxide dioxygenase activity
HAU86_RS08830	COG0861	Integral membrane protein TerC family
HAU86_RS08850	COG2267	carboxylic ester hydrolase activity
HAU86_RS08855	COG0431	NADPH-dependent FMN reductase
HAU86_RS08865	COG2197	response regulator
HAU86_RS08885	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HAU86_RS08890	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HAU86_RS08910	COG0215	cysteine-tRNA ligase activity
HAU86_RS08920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HAU86_RS08935	COG5265	(ABC) transporter
HAU86_RS08940	COG0688	phosphatidylethanolamine metabolic process
HAU86_RS08945	COG1183	phosphatidylcholine synthase activity
HAU86_RS08960	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HAU86_RS08970	COG3158	transport of potassium into the cell
HAU86_RS08975	COG3158	transport of potassium into the cell
HAU86_RS08985	COG0436	Aminotransferase
HAU86_RS08990	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HAU86_RS09000	COG3710	Transcriptional regulator
HAU86_RS09000	COG0457	Tetratricopeptide repeat
HAU86_RS09010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HAU86_RS09020	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HAU86_RS09025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HAU86_RS09080	COG2010	Cytochrome c
HAU86_RS09080	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HAU86_RS09085	COG2080	2 iron, 2 sulfur cluster binding
HAU86_RS09125	COG1846	Transcriptional regulator
HAU86_RS09155	COG2124	cytochrome p450
HAU86_RS09185	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HAU86_RS09230	COG0318	PFAM AMP-dependent synthetase and ligase
HAU86_RS09235	COG2072	flavoprotein involved in K transport
HAU86_RS09310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAU86_RS09315	COG1309	transcriptional regulator
HAU86_RS09320	COG0154	amidase activity
HAU86_RS09325	COG3415	Transposase
HAU86_RS09325	COG2801	Transposase and inactivated derivatives
HAU86_RS09330	COG2814	Major facilitator Superfamily
HAU86_RS09335	COG1012	belongs to the aldehyde dehydrogenase family
HAU86_RS09340	COG1802	Transcriptional regulator
HAU86_RS09350	COG0477	Major facilitator Superfamily
HAU86_RS09355	COG0402	S-adenosylhomocysteine deaminase activity
HAU86_RS09365	COG0789	Transcriptional regulator
HAU86_RS09375	COG1234	tRNA 3'-trailer cleavage
HAU86_RS09395	COG5507	3-demethylubiquinone-9 3-methyltransferase
HAU86_RS09415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAU86_RS09420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAU86_RS09430	COG4774	siderophore transport
HAU86_RS09435	COG3128	pkhd-type hydroxylase
HAU86_RS09445	COG0848	biopolymer transport protein
HAU86_RS09460	COG1994	Peptidase M50
HAU86_RS09475	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS09485	COG0129	dihydroxy-acid dehydratase activity
HAU86_RS09490	COG1609	Transcriptional regulator
HAU86_RS09495	COG3842	ATPase activity
HAU86_RS09510	COG0395	ABC-type sugar transport system, permease component
HAU86_RS09515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HAU86_RS09520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HAU86_RS09525	COG0800	Aldolase
HAU86_RS09530	COG0183	Belongs to the thiolase family
HAU86_RS09540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HAU86_RS09545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HAU86_RS09565	COG2066	Belongs to the glutaminase family
HAU86_RS09565	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
HAU86_RS09590	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HAU86_RS09605	COG0277	FAD linked oxidase domain protein
HAU86_RS09615	COG2271	Major facilitator Superfamily
HAU86_RS09620	COG0183	Belongs to the thiolase family
HAU86_RS09625	COG1024	Enoyl-CoA hydratase
HAU86_RS09650	COG1960	acyl-CoA dehydrogenase activity
HAU86_RS09675	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS09695	COG1671	Belongs to the UPF0178 family
HAU86_RS09715	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
HAU86_RS09730	COG2130	NADP-dependent
HAU86_RS09760	COG1278	Cold shock
HAU86_RS09770	COG2814	Major facilitator Superfamily
HAU86_RS09785	COG0519	Catalyzes the synthesis of GMP from XMP
HAU86_RS09785	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HAU86_RS09815	COG0640	Transcriptional regulator
HAU86_RS09825	COG0701	Predicted permease
HAU86_RS09830	COG0242	peptide deformylase activity
HAU86_RS09835	COG0583	DNA-binding transcription factor activity
HAU86_RS09845	COG1063	alcohol dehydrogenase
HAU86_RS09910	COG0625	glutathione transferase activity
HAU86_RS09920	COG1393	Belongs to the ArsC family
HAU86_RS09945	COG0559	Belongs to the binding-protein-dependent transport system permease family
HAU86_RS09955	COG1392	Phosphate transport regulator
HAU86_RS09960	COG0306	phosphate transporter
HAU86_RS10000	COG1160	GTP binding
HAU86_RS10020	COG0300	oxidoreductase activity
HAU86_RS10025	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HAU86_RS10030	COG1286	toxin biosynthetic process
HAU86_RS10040	COG1879	ABC-type sugar transport system periplasmic component
HAU86_RS10065	COG0297	glycogen (starch) synthase activity
HAU86_RS10080	COG0708	Exodeoxyribonuclease III
HAU86_RS10090	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HAU86_RS10095	COG0305	Participates in initiation and elongation during chromosome replication
HAU86_RS10105	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HAU86_RS10125	COG0359	binds to the 23S rRNA
HAU86_RS10135	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HAU86_RS10140	COG0360	Binds together with S18 to 16S ribosomal RNA
HAU86_RS10155	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HAU86_RS10165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HAU86_RS10170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HAU86_RS10175	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HAU86_RS10180	COG1561	YicC-like family, N-terminal region
HAU86_RS10185	COG0194	GDP metabolic process
HAU86_RS10205	COG3964	amidohydrolase
HAU86_RS10235	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
HAU86_RS10265	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HAU86_RS10270	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HAU86_RS10280	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HAU86_RS10295	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HAU86_RS10310	COG0488	(ABC) transporter
HAU86_RS10325	COG0105	UTP biosynthetic process
HAU86_RS10330	COG0861	Integral membrane protein TerC family
HAU86_RS10375	COG0248	Ppx GppA phosphatase
HAU86_RS10380	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HAU86_RS10390	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HAU86_RS10395	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HAU86_RS10400	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HAU86_RS10410	COG1278	Cold shock
HAU86_RS10430	COG2153	protein acetylation
HAU86_RS10445	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HAU86_RS10450	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HAU86_RS10465	COG1175	transmembrane transport
HAU86_RS10475	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HAU86_RS10480	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HAU86_RS10490	COG0280	phosphate acetyltransferase
HAU86_RS10490	COG0281	malic enzyme
HAU86_RS10510	COG0386	Belongs to the glutathione peroxidase family
HAU86_RS10520	COG3045	CreA protein
HAU86_RS10555	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HAU86_RS10565	COG3483	tryptophan 2,3-dioxygenase activity
HAU86_RS10600	COG2365	Tyrosine phosphatase family
HAU86_RS10615	COG0174	glutamine synthetase
HAU86_RS10650	COG1278	Cold shock
HAU86_RS10665	COG0488	(ABC) transporter
HAU86_RS10695	COG0778	Nitroreductase
HAU86_RS10720	COG2207	Transcriptional regulator
HAU86_RS10740	COG0840	transmembrane signaling receptor activity
HAU86_RS10760	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
HAU86_RS10785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HAU86_RS10790	COG1309	transcriptional regulator
HAU86_RS10800	COG0850	regulation of cytokinetic process
HAU86_RS10805	COG2894	cell division
HAU86_RS10810	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HAU86_RS10845	COG1376	ErfK ybiS ycfS ynhG family protein
HAU86_RS10905	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HAU86_RS10935	COG2824	Alkylphosphonate utilization operon protein PhnA
HAU86_RS10975	COG4106	trans-aconitate 2-methyltransferase activity
HAU86_RS11000	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HAU86_RS11005	COG0697	spore germination
HAU86_RS11035	COG0784	Response regulator, receiver
HAU86_RS11035	COG4191	Histidine kinase
HAU86_RS11105	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HAU86_RS11110	COG3920	Histidine kinase
HAU86_RS11115	COG0784	Response regulator, receiver
HAU86_RS11120	COG5002	protein histidine kinase activity
HAU86_RS11125	COG0439	Biotin carboxylase
HAU86_RS11130	COG0511	ligase activity, forming carbon-carbon bonds
HAU86_RS11135	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HAU86_RS11155	COG0436	Aminotransferase
HAU86_RS11160	COG1268	BioY protein
HAU86_RS11165	COG1301	dicarboxylic acid transport
HAU86_RS11180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HAU86_RS11185	COG1530	ribonuclease E activity
HAU86_RS11185	COG1530	ribonuclease E activity
HAU86_RS11195	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HAU86_RS11205	COG2084	Dehydrogenase
HAU86_RS11210	COG0697	spore germination
HAU86_RS11220	COG0739	heme binding
HAU86_RS11240	COG2259	Doxx family
HAU86_RS11245	COG2271	Major facilitator Superfamily
HAU86_RS11250	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HAU86_RS11255	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HAU86_RS11260	COG0625	glutathione transferase activity
HAU86_RS11265	COG2945	thiolester hydrolase activity
HAU86_RS11270	COG1104	cysteine desulfurase activity
HAU86_RS11275	COG0719	Fe-S assembly protein
HAU86_RS11280	COG0396	ATPase activity
HAU86_RS11285	COG0719	Fe-S assembly protein
HAU86_RS11290	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HAU86_RS11300	COG0316	Belongs to the HesB IscA family
HAU86_RS11310	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HAU86_RS11320	COG0513	Belongs to the DEAD box helicase family
HAU86_RS11350	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS11365	COG0187	DNA topoisomerase II activity
HAU86_RS11370	COG0586	Pfam SNARE associated Golgi protein
HAU86_RS11385	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HAU86_RS11400	COG3243	poly(R)-hydroxyalkanoic acid synthase
HAU86_RS11410	COG0436	Aminotransferase
HAU86_RS11420	COG1494	fructose-1,6-bisphosphatase
HAU86_RS11445	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HAU86_RS11450	COG1802	Transcriptional regulator
HAU86_RS11455	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HAU86_RS11480	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HAU86_RS11495	COG0840	transmembrane signaling receptor activity
HAU86_RS11500	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HAU86_RS11540	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HAU86_RS11550	COG2354	Protein conserved in bacteria
HAU86_RS11560	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HAU86_RS11580	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HAU86_RS11615	COG0463	Glycosyl transferase, family 2
HAU86_RS11665	COG3077	Addiction module antitoxin, RelB DinJ family
HAU86_RS11695	COG0776	regulation of translation
HAU86_RS11730	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HAU86_RS11785	COG1522	sequence-specific DNA binding
HAU86_RS11795	COG1960	acyl-CoA dehydrogenase activity
HAU86_RS11800	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HAU86_RS11825	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HAU86_RS11885	COG2373	Large extracellular alpha-helical protein
HAU86_RS11890	COG4953	penicillin-binding protein 1C
HAU86_RS11900	COG0671	phosphoesterase, PA-phosphatase related
HAU86_RS11905	COG0463	Glycosyl transferase, family 2
HAU86_RS11915	COG1309	transcriptional regulator
HAU86_RS11925	COG1283	sodium-dependent phosphate transmembrane transporter activity
HAU86_RS11930	COG0626	cystathionine gamma-synthase activity
HAU86_RS11935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HAU86_RS11940	COG4597	amino acid ABC transporter
HAU86_RS11945	COG0765	amino acid transport
HAU86_RS11950	COG1126	abc transporter atp-binding protein
HAU86_RS11990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAU86_RS12055	COG0251	oxidation-reduction process
HAU86_RS12070	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HAU86_RS12085	COG0525	valine-tRNA ligase activity
HAU86_RS12090	COG2094	Belongs to the DNA glycosylase MPG family
HAU86_RS12095	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HAU86_RS12100	COG2867	negative regulation of translational initiation
HAU86_RS12105	COG2863	cytochrome
HAU86_RS12110	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HAU86_RS12130	COG2863	cytochrome
HAU86_RS12135	COG0668	transmembrane transport
HAU86_RS12140	COG1058	Belongs to the CinA family
HAU86_RS12140	COG1546	Belongs to the CinA family
HAU86_RS12145	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HAU86_RS12145	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HAU86_RS12165	COG5000	phosphorelay sensor kinase activity
HAU86_RS12170	COG2204	response regulator
HAU86_RS12175	COG1923	regulation of RNA biosynthetic process
HAU86_RS12180	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HAU86_RS12185	COG3956	TIGRFAM MazG family protein
HAU86_RS12190	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HAU86_RS12210	COG1024	Enoyl-CoA hydratase
HAU86_RS12230	COG4774	siderophore transport
HAU86_RS12245	COG4178	(ABC) transporter
HAU86_RS12270	COG3237	CsbD-like
HAU86_RS12295	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HAU86_RS12300	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HAU86_RS12305	COG0318	PFAM AMP-dependent synthetase and ligase
HAU86_RS12325	COG0321	lipoyl(octanoyl) transferase activity
HAU86_RS12325	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HAU86_RS12330	COG0084	hydrolase, TatD family'
HAU86_RS12350	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HAU86_RS12355	COG1686	Belongs to the peptidase S11 family
HAU86_RS12360	COG2267	carboxylic ester hydrolase activity
HAU86_RS12400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HAU86_RS12420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAU86_RS12430	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
HAU86_RS12485	COG0129	dihydroxy-acid dehydratase activity
HAU86_RS12490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HAU86_RS12495	COG0601	transmembrane transport
HAU86_RS12505	COG0444	Belongs to the ABC transporter superfamily
HAU86_RS12525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HAU86_RS12525	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HAU86_RS12535	COG1335	isochorismatase
HAU86_RS12570	COG1175	transmembrane transport
HAU86_RS12575	COG0395	ABC-type sugar transport system, permease component
HAU86_RS12620	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HAU86_RS12620	COG0473	3-isopropylmalate dehydrogenase activity
HAU86_RS12630	COG1984	allophanate hydrolase subunit 2
HAU86_RS12635	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
HAU86_RS12645	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HAU86_RS12650	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HAU86_RS12655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HAU86_RS12655	COG1116	anion transmembrane transporter activity
HAU86_RS12660	COG3707	response regulator
HAU86_RS12665	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HAU86_RS12670	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HAU86_RS12675	COG0789	Transcriptional regulator
HAU86_RS12690	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HAU86_RS12700	COG1253	flavin adenine dinucleotide binding
HAU86_RS12705	COG1183	phosphatidylcholine synthase activity
HAU86_RS12710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HAU86_RS12715	COG0679	Auxin Efflux Carrier
HAU86_RS12755	COG1278	Cold shock
HAU86_RS12760	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HAU86_RS12775	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HAU86_RS12790	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HAU86_RS12800	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HAU86_RS12860	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HAU86_RS12880	COG0628	permease
HAU86_RS12895	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HAU86_RS12920	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HAU86_RS12965	COG0343	queuine tRNA-ribosyltransferase activity
HAU86_RS12975	COG1309	transcriptional regulator
HAU86_RS12985	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HAU86_RS12990	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HAU86_RS13010	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HAU86_RS13020	COG3158	transport of potassium into the cell
HAU86_RS13025	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HAU86_RS13030	COG0629	single-stranded DNA binding
HAU86_RS13040	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HAU86_RS13060	COG0546	phosphoglycolate phosphatase activity
HAU86_RS13150	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HAU86_RS13160	COG2340	Cysteine-rich secretory protein family
HAU86_RS13180	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HAU86_RS13200	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HAU86_RS13205	COG1862	Preprotein translocase
HAU86_RS13220	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HAU86_RS13230	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HAU86_RS13240	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HAU86_RS13245	COG0805	protein transport
HAU86_RS13250	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HAU86_RS13255	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HAU86_RS13260	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HAU86_RS13265	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HAU86_RS13270	COG1472	Belongs to the glycosyl hydrolase 3 family
HAU86_RS13280	COG0018	arginyl-trna synthetase
HAU86_RS13285	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HAU86_RS13295	COG5002	protein histidine kinase activity
HAU86_RS13295	COG2198	Histidine kinase
HAU86_RS13295	COG0784	Response regulator, receiver
HAU86_RS13300	COG0708	Exodeoxyribonuclease III
HAU86_RS13305	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HAU86_RS13310	COG0129	dihydroxy-acid dehydratase activity
HAU86_RS13320	COG4206	TonB-dependent receptor
HAU86_RS13330	COG2202	Pas domain
HAU86_RS13330	COG3920	Histidine kinase
HAU86_RS13370	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HAU86_RS13375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HAU86_RS13385	COG0508	dehydrogenase complex catalyzes the overall conversion of
HAU86_RS13400	COG0022	dehydrogenase e1 component
HAU86_RS13400	COG0508	dehydrogenase complex catalyzes the overall conversion of
HAU86_RS13405	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HAU86_RS13415	COG0431	NADPH-dependent FMN reductase
HAU86_RS13430	COG4221	oxidoreductase activity
HAU86_RS13440	COG0148	phosphopyruvate hydratase activity
HAU86_RS13445	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HAU86_RS13450	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
HAU86_RS13450	COG2066	Belongs to the glutaminase family
HAU86_RS13455	COG0477	Major facilitator Superfamily
HAU86_RS13460	COG2877	3-deoxy-8-phosphooctulonate synthase activity
HAU86_RS13470	COG0745	RESPONSE REGULATOR receiver
HAU86_RS13480	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HAU86_RS13485	COG0504	CTP synthase activity
HAU86_RS13495	COG0149	triose-phosphate isomerase activity
HAU86_RS13500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HAU86_RS13505	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HAU86_RS13510	COG0134	indole-3-glycerol-phosphate synthase activity
HAU86_RS13515	COG0315	cyclic pyranopterin monophosphate synthase activity
HAU86_RS13520	COG5001	Diguanylate cyclase
HAU86_RS13520	COG3300	MHYT domain
HAU86_RS13525	COG0793	Belongs to the peptidase S41A family
HAU86_RS13530	COG1304	FMN binding
HAU86_RS13535	COG1011	Hydrolase
HAU86_RS13545	COG0303	'Molybdopterin
HAU86_RS13550	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HAU86_RS13575	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HAU86_RS13580	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HAU86_RS13585	COG0372	Belongs to the citrate synthase family
HAU86_RS13600	COG1175	transmembrane transport
HAU86_RS13605	COG0395	ABC-type sugar transport system, permease component
HAU86_RS13615	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS13640	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HAU86_RS13650	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HAU86_RS13660	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HAU86_RS13665	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HAU86_RS13670	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HAU86_RS13675	COG0750	zinc metalloprotease
HAU86_RS13680	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HAU86_RS13690	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HAU86_RS13695	COG0233	cytoplasmic translational termination
HAU86_RS13700	COG0528	UMP kinase activity
HAU86_RS13705	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HAU86_RS13710	COG0052	Belongs to the universal ribosomal protein uS2 family
HAU86_RS13750	COG2814	Major facilitator Superfamily
HAU86_RS13760	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HAU86_RS13765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HAU86_RS13770	COG0024	Methionine aminopeptidase
HAU86_RS13780	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HAU86_RS13790	COG0604	alcohol dehydrogenase
HAU86_RS13795	COG1136	(ABC) transporter
HAU86_RS13805	COG0442	prolyl-tRNA aminoacylation
HAU86_RS13835	COG4774	siderophore transport
HAU86_RS13855	COG1129	ABC transporter
HAU86_RS13860	COG1172	Belongs to the binding-protein-dependent transport system permease family
HAU86_RS13865	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HAU86_RS13880	COG0346	lactoylglutathione lyase activity
HAU86_RS13890	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HAU86_RS13890	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HAU86_RS13895	COG1007	ATP synthesis coupled electron transport
HAU86_RS13910	COG0713	ATP synthesis coupled electron transport
HAU86_RS13920	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HAU86_RS13925	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HAU86_RS13935	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HAU86_RS13945	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
HAU86_RS13955	COG0649	NAD binding
HAU86_RS13965	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HAU86_RS13975	COG4774	siderophore transport
HAU86_RS13995	COG2195	Cleaves the N-terminal amino acid of tripeptides
HAU86_RS14035	COG2226	methyltransferase
HAU86_RS14050	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HAU86_RS14055	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HAU86_RS14065	COG0740	serine-type endopeptidase activity
HAU86_RS14070	COG0544	peptidyl-prolyl cis-trans isomerase activity
HAU86_RS14085	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HAU86_RS14085	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HAU86_RS14090	COG0347	Belongs to the P(II) protein family
HAU86_RS14095	COG0174	glutamine synthetase
HAU86_RS14135	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HAU86_RS14160	COG3706	GGDEF domain
HAU86_RS14165	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HAU86_RS14170	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HAU86_RS14180	COG1024	Enoyl-CoA hydratase
HAU86_RS14200	COG1612	heme a metabolic process
HAU86_RS14225	COG0297	glycogen (starch) synthase activity
HAU86_RS14240	COG1846	Transcriptional regulator
HAU86_RS14245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HAU86_RS14250	COG3268	Saccharopine dehydrogenase
HAU86_RS14255	COG3268	Saccharopine dehydrogenase
HAU86_RS14335	COG0776	regulation of translation
HAU86_RS14340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HAU86_RS14345	COG0416	fatty acid biosynthetic process
HAU86_RS14375	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
HAU86_RS14380	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HAU86_RS14385	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HAU86_RS14390	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HAU86_RS14400	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HAU86_RS14400	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HAU86_RS14405	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HAU86_RS14410	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HAU86_RS14435	COG0113	porphobilinogen synthase activity
HAU86_RS14445	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
HAU86_RS14470	COG1914	H( )-stimulated, divalent metal cation uptake system
HAU86_RS14495	COG0697	spore germination
HAU86_RS14555	COG0747	negative chemotaxis
HAU86_RS14560	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HAU86_RS14570	COG1381	Involved in DNA repair and RecF pathway recombination
HAU86_RS14580	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HAU86_RS14585	COG0571	ribonuclease III activity
HAU86_RS14590	COG0681	Belongs to the peptidase S26 family
HAU86_RS14595	COG0736	holo-[acyl-carrier-protein] synthase activity
HAU86_RS14600	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HAU86_RS14610	COG1758	RNA polymerase activity
HAU86_RS14630	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HAU86_RS14635	COG1970	mechanosensitive ion channel activity
HAU86_RS14640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HAU86_RS14645	COG0741	lytic transglycosylase activity
HAU86_RS14675	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HAU86_RS14685	COG0154	amidase activity
HAU86_RS14695	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HAU86_RS14700	COG2070	2-Nitropropane dioxygenase
HAU86_RS14710	COG0583	DNA-binding transcription factor activity
HAU86_RS14715	COG3591	Belongs to the peptidase S1B family
HAU86_RS14715	COG1864	DNA RNA non-specific endonuclease
HAU86_RS14725	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HAU86_RS14740	COG1960	acyl-CoA dehydrogenase activity
HAU86_RS14750	COG0540	Belongs to the ATCase OTCase family
HAU86_RS14760	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HAU86_RS14770	COG0154	amidase activity
HAU86_RS14775	COG0758	DNA mediated transformation
HAU86_RS14780	COG1733	regulation of RNA biosynthetic process
HAU86_RS14785	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HAU86_RS14790	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS14805	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HAU86_RS14810	COG0557	exoribonuclease II activity
HAU86_RS14830	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HAU86_RS14870	COG0583	DNA-binding transcription factor activity
HAU86_RS14905	COG0784	Response regulator, receiver
HAU86_RS14915	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HAU86_RS14950	COG0537	adenosine 5'-monophosphoramidase activity
HAU86_RS14955	COG1720	tRNA m6t6A37 methyltransferase activity
HAU86_RS15000	COG1482	cell wall glycoprotein biosynthetic process
HAU86_RS15025	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HAU86_RS15035	COG0840	transmembrane signaling receptor activity
HAU86_RS15040	COG0667	Aldo Keto reductase
HAU86_RS15055	COG2814	Major facilitator Superfamily
HAU86_RS15070	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HAU86_RS15085	COG1686	Belongs to the peptidase S11 family
HAU86_RS15105	COG1192	Involved in chromosome partitioning
HAU86_RS15110	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HAU86_RS15155	COG2239	Acts as a magnesium transporter
HAU86_RS15190	COG4977	sequence-specific DNA binding
HAU86_RS15245	COG0523	cobalamin synthesis protein
HAU86_RS15265	COG0321	lipoyl(octanoyl) transferase activity
HAU86_RS15295	COG1254	Belongs to the acylphosphatase family
HAU86_RS15300	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HAU86_RS15305	COG4770	biotin carboxylase activity
HAU86_RS15315	COG4191	Histidine kinase
HAU86_RS15315	COG0784	Response regulator, receiver
HAU86_RS15335	COG2271	Major facilitator Superfamily
HAU86_RS15345	COG4948	Mandelate Racemase Muconate Lactonizing
HAU86_RS15350	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS15355	COG1063	alcohol dehydrogenase
HAU86_RS15370	COG2197	response regulator
HAU86_RS15385	COG1414	Transcriptional regulator
HAU86_RS15390	COG2124	cytochrome p450
HAU86_RS15400	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HAU86_RS15405	COG0179	Fumarylacetoacetate (FAA) hydrolase
HAU86_RS15440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HAU86_RS15490	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS15535	COG4566	intracellular signal transduction
HAU86_RS15540	COG1566	PFAM secretion protein HlyD family protein
HAU86_RS15545	COG0577	efflux transmembrane transporter activity
HAU86_RS15545	COG1136	(ABC) transporter
HAU86_RS15550	COG0577	efflux transmembrane transporter activity
HAU86_RS15550	COG1136	(ABC) transporter
HAU86_RS15555	COG2197	response regulator
HAU86_RS15575	COG0450	alkyl hydroperoxide reductase
HAU86_RS15580	COG0415	Belongs to the DNA photolyase family
HAU86_RS15625	COG0583	DNA-binding transcription factor activity
HAU86_RS15685	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS15690	COG2030	dehydratase
HAU86_RS15710	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HAU86_RS15710	COG2010	Cytochrome c
HAU86_RS15715	COG2860	membrane
HAU86_RS15780	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HAU86_RS15795	COG3415	Transposase
HAU86_RS15795	COG2801	Transposase and inactivated derivatives
HAU86_RS15810	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HAU86_RS15835	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HAU86_RS15850	COG1733	regulation of RNA biosynthetic process
HAU86_RS15865	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS15870	COG0203	ribosomal protein L17
HAU86_RS15875	COG0202	RNA polymerase activity
HAU86_RS15880	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HAU86_RS15885	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HAU86_RS15890	COG0563	adenylate kinase activity
HAU86_RS15900	COG0200	Binds to the 23S rRNA
HAU86_RS15905	COG1841	ribosomal large subunit assembly
HAU86_RS15910	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HAU86_RS15915	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HAU86_RS15920	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HAU86_RS15925	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HAU86_RS15930	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HAU86_RS15935	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HAU86_RS15940	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HAU86_RS15945	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HAU86_RS15950	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HAU86_RS15955	COG0255	Belongs to the universal ribosomal protein uL29 family
HAU86_RS15960	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HAU86_RS15965	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HAU86_RS15970	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HAU86_RS15975	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HAU86_RS15980	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HAU86_RS15985	COG0089	rRNA binding
HAU86_RS15990	COG0088	Forms part of the polypeptide exit tunnel
HAU86_RS15995	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HAU86_RS16000	COG0051	transcription antitermination factor activity, RNA binding
HAU86_RS16005	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HAU86_RS16010	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HAU86_RS16015	COG0049	tRNA binding
HAU86_RS16020	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HAU86_RS16030	COG1132	(ABC) transporter
HAU86_RS16035	COG1231	oxidoreductase activity
HAU86_RS16040	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAU86_RS16045	COG0085	RNA polymerase activity
HAU86_RS16050	COG0222	ribosome binding
HAU86_RS16055	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HAU86_RS16060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HAU86_RS16065	COG0081	regulation of translation
HAU86_RS16070	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HAU86_RS16080	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HAU86_RS16100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HAU86_RS16105	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HAU86_RS16105	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HAU86_RS16110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HAU86_RS16125	COG3959	Transketolase, thiamine diphosphate binding domain
HAU86_RS16130	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HAU86_RS16155	COG2226	methyltransferase
HAU86_RS16190	COG0673	inositol 2-dehydrogenase activity
HAU86_RS16230	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS16235	COG0406	alpha-ribazole phosphatase activity
HAU86_RS16240	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS16250	COG2827	Endonuclease containing a URI domain
HAU86_RS16260	COG1960	acyl-CoA dehydrogenase activity
HAU86_RS16265	COG1309	transcriptional regulator
HAU86_RS16280	COG3246	L-lysine catabolic process to acetate
HAU86_RS16320	COG0662	Cupin 2, conserved barrel domain protein
HAU86_RS16345	COG0829	nickel cation binding
HAU86_RS16350	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HAU86_RS16355	COG0804	urea catabolic process
HAU86_RS16360	COG0831	urea catabolic process
HAU86_RS16360	COG0832	Belongs to the urease beta subunit family
HAU86_RS16365	COG0830	nickel cation binding
HAU86_RS16370	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
HAU86_RS16440	COG3795	YCII-related domain
HAU86_RS16460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HAU86_RS16480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HAU86_RS16585	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HAU86_RS16610	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HAU86_RS16615	COG0302	gtp cyclohydrolase
HAU86_RS16630	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HAU86_RS16650	COG0477	Major facilitator Superfamily
HAU86_RS16665	COG0531	amino acid
HAU86_RS16685	COG2814	Major facilitator Superfamily
HAU86_RS16690	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HAU86_RS16705	COG5001	Diguanylate cyclase
HAU86_RS16745	COG1752	Esterase of the alpha-beta hydrolase superfamily
HAU86_RS16750	COG0517	IMP dehydrogenase activity
HAU86_RS16790	COG0662	Cupin 2, conserved barrel domain protein
HAU86_RS16805	COG1063	alcohol dehydrogenase
HAU86_RS16840	COG3842	ATPase activity
HAU86_RS16850	COG1176	ABC-type spermidine putrescine transport system, permease component I
HAU86_RS16855	COG3833	ABC-type maltose transport systems, permease component
HAU86_RS16930	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HAU86_RS16945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HAU86_RS16975	COG0463	Glycosyl transferase, family 2
HAU86_RS16985	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HAU86_RS17000	COG0747	negative chemotaxis
HAU86_RS17015	COG0601	transmembrane transport
HAU86_RS17020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HAU86_RS17035	COG1473	amidohydrolase
HAU86_RS17040	COG0154	amidase activity
HAU86_RS17045	COG1024	Enoyl-CoA hydratase
HAU86_RS17050	COG0604	alcohol dehydrogenase
HAU86_RS17050	COG3321	synthase
HAU86_RS17060	COG0625	glutathione transferase activity
HAU86_RS17075	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
HAU86_RS17080	COG1058	Belongs to the CinA family
HAU86_RS17080	COG1546	Belongs to the CinA family
HAU86_RS17085	COG2308	Evidence 4 Homologs of previously reported genes of
HAU86_RS17095	COG1305	Transglutaminase-like
HAU86_RS17110	COG4221	oxidoreductase activity
HAU86_RS17120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HAU86_RS17145	COG5425	PFAM Usg family protein
HAU86_RS17150	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HAU86_RS17155	COG0459	protein refolding
HAU86_RS17160	COG0681	Belongs to the peptidase S26 family
HAU86_RS17175	COG0625	glutathione transferase activity
HAU86_RS17230	COG0384	phenazine biosynthesis protein PhzF
HAU86_RS17240	COG0842	Transport permease protein
HAU86_RS17245	COG1131	(ABC) transporter
HAU86_RS17260	COG0640	Transcriptional regulator
HAU86_RS17295	COG3608	succinylglutamate desuccinylase aspartoacylase
HAU86_RS17295	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HAU86_RS17330	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HAU86_RS17335	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HAU86_RS17340	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HAU86_RS17380	COG2204	response regulator
HAU86_RS17385	COG0784	Response regulator, receiver
HAU86_RS17385	COG4191	Histidine kinase
HAU86_RS17420	COG0515	serine threonine protein kinase
HAU86_RS17420	COG2815	serine threonine protein kinase
HAU86_RS17460	COG1309	transcriptional regulator
HAU86_RS17465	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HAU86_RS17470	COG1473	amidohydrolase
HAU86_RS17480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HAU86_RS17485	COG5001	Diguanylate cyclase
HAU86_RS17490	COG0318	PFAM AMP-dependent synthetase and ligase
HAU86_RS17495	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HAU86_RS17530	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HAU86_RS17550	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HAU86_RS17555	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HAU86_RS17560	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HAU86_RS17565	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
HAU86_RS17600	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HAU86_RS17615	COG0047	phosphoribosylformylglycinamidine synthase activity
HAU86_RS17620	COG0598	Magnesium transport protein CorA
HAU86_RS17625	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HAU86_RS17630	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HAU86_RS17640	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
HAU86_RS17645	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HAU86_RS17645	COG1116	anion transmembrane transporter activity
HAU86_RS17650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HAU86_RS17655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HAU86_RS17680	COG1309	transcriptional regulator
HAU86_RS17685	COG2267	carboxylic ester hydrolase activity
HAU86_RS17690	COG2020	methyltransferase activity
HAU86_RS17700	COG0604	alcohol dehydrogenase
HAU86_RS17725	COG0538	isocitrate dehydrogenase activity
HAU86_RS17740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HAU86_RS17745	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HAU86_RS17750	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HAU86_RS17755	COG0509	glycine decarboxylation via glycine cleavage system
HAU86_RS17760	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HAU86_RS17760	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HAU86_RS17770	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HAU86_RS17840	COG4993	Dehydrogenase
HAU86_RS17875	COG0640	Transcriptional regulator
HAU86_RS17880	COG0446	pyridine nucleotide-disulphide oxidoreductase
HAU86_RS17985	COG2917	probably involved in intracellular septation
HAU86_RS18000	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HAU86_RS18000	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HAU86_RS18045	COG1684	flagellar biosynthetic protein fliR
HAU86_RS18050	COG1987	bacterial-type flagellum assembly
HAU86_RS18055	COG1677	Flagellar hook-basal body complex protein FliE
HAU86_RS18060	COG1558	bacterial-type flagellum-dependent cell motility
HAU86_RS18075	COG1338	Plays a role in the flagellum-specific transport system
HAU86_RS18105	COG4786	Flagellar basal body rod
HAU86_RS18110	COG4786	Flagellar basal body rod
HAU86_RS18120	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HAU86_RS18130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HAU86_RS18135	COG1733	regulation of RNA biosynthetic process
HAU86_RS18145	COG2910	NAD(P)H-binding
HAU86_RS18150	COG1733	regulation of RNA biosynthetic process
HAU86_RS18160	COG1706	bacterial-type flagellum-dependent cell motility
HAU86_RS18180	COG5442	Flagellar protein FlaF
HAU86_RS18185	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HAU86_RS18190	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HAU86_RS18195	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HAU86_RS18200	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HAU86_RS18205	COG5443	negative regulation of bacterial-type flagellum assembly
HAU86_RS18240	COG1749	Flagellar hook protein flgE
HAU86_RS18245	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HAU86_RS18250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HAU86_RS18280	COG2267	carboxylic ester hydrolase activity
HAU86_RS18290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HAU86_RS18305	COG3300	MHYT domain
HAU86_RS18305	COG5001	Diguanylate cyclase
HAU86_RS18310	COG0477	Major facilitator Superfamily
HAU86_RS18315	COG3685	Protein conserved in bacteria
HAU86_RS18335	COG0583	DNA-binding transcription factor activity
HAU86_RS18340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HAU86_RS18350	COG1012	belongs to the aldehyde dehydrogenase family
HAU86_RS18355	COG2721	sulfolactate sulfo-lyase activity
HAU86_RS18370	COG0745	RESPONSE REGULATOR receiver
HAU86_RS18375	COG2205	protein histidine kinase activity
HAU86_RS18395	COG0492	ferredoxin-NADP+ reductase activity
HAU86_RS18405	COG0633	Ferredoxin
HAU86_RS18420	COG3218	ABC-type transport auxiliary lipoprotein component
HAU86_RS18420	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HAU86_RS18425	COG1127	ABC transporter
HAU86_RS18430	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HAU86_RS18435	COG4948	Mandelate Racemase Muconate Lactonizing
HAU86_RS18440	COG2814	Major facilitator Superfamily
HAU86_RS18460	COG4154	Belongs to the RbsD FucU family
HAU86_RS18485	COG0351	phosphomethylpyrimidine kinase
HAU86_RS18495	COG2010	Cytochrome c
HAU86_RS18510	COG3909	cytochrome
HAU86_RS18530	COG0728	peptidoglycan biosynthetic process
HAU86_RS18540	COG0673	inositol 2-dehydrogenase activity
HAU86_RS18545	COG0662	Cupin 2, conserved barrel domain protein
HAU86_RS18545	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
HAU86_RS18585	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HAU86_RS18585	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HAU86_RS18595	COG0859	PFAM glycosyl transferase family 9
HAU86_RS18610	COG1132	(ABC) transporter
HAU86_RS18635	COG0583	DNA-binding transcription factor activity
HAU86_RS18640	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS18660	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HAU86_RS18665	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HAU86_RS18680	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HAU86_RS18735	COG4191	Histidine kinase
HAU86_RS18735	COG0784	Response regulator, receiver
HAU86_RS18740	COG3920	Histidine kinase
HAU86_RS18755	COG0318	PFAM AMP-dependent synthetase and ligase
HAU86_RS18780	COG2942	2-epimerase
HAU86_RS18785	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HAU86_RS18795	COG1475	DNA binding
HAU86_RS18840	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HAU86_RS18860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HAU86_RS18885	COG0367	asparagine synthase
HAU86_RS18890	COG0463	Glycosyl transferase, family 2
HAU86_RS18900	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HAU86_RS18930	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HAU86_RS18960	COG1132	(ABC) transporter
HAU86_RS18990	COG0107	imidazoleglycerol-phosphate synthase activity
HAU86_RS19000	COG2089	acid synthase
HAU86_RS19005	COG1083	cytidylyl-transferase
HAU86_RS19025	COG0438	transferase activity, transferring glycosyl groups
HAU86_RS19040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HAU86_RS19075	COG1024	Enoyl-CoA hydratase
HAU86_RS19080	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HAU86_RS19085	COG0277	FAD linked oxidase domain protein
HAU86_RS19085	COG0247	lactate metabolic process
HAU86_RS19095	COG1024	Enoyl-CoA hydratase
HAU86_RS19105	COG0243	molybdopterin cofactor binding
HAU86_RS19110	COG3181	Tripartite tricarboxylate transporter family receptor
HAU86_RS19115	COG2080	2 iron, 2 sulfur cluster binding
HAU86_RS19120	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HAU86_RS19120	COG2010	Cytochrome c
HAU86_RS19145	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HAU86_RS19150	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
HAU86_RS19160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HAU86_RS19165	COG2010	Cytochrome c
HAU86_RS19170	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HAU86_RS19170	COG3218	ABC-type transport auxiliary lipoprotein component
HAU86_RS19175	COG1127	ABC transporter
HAU86_RS19195	COG0045	succinate-CoA ligase (ADP-forming) activity
HAU86_RS19195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HAU86_RS19195	COG1042	CoA-binding domain protein
HAU86_RS19220	COG3243	poly(R)-hydroxyalkanoic acid synthase
HAU86_RS19225	COG0517	IMP dehydrogenase activity
HAU86_RS19225	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HAU86_RS19225	COG0617	tRNA 3'-terminal CCA addition
HAU86_RS19230	COG0251	oxidation-reduction process
HAU86_RS19265	COG1024	Enoyl-CoA hydratase
HAU86_RS19270	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS19280	COG1960	acyl-CoA dehydrogenase activity
HAU86_RS19285	COG0318	PFAM AMP-dependent synthetase and ligase
HAU86_RS19295	COG1250	3-hydroxyacyl-CoA dehydrogenase
HAU86_RS19305	COG4176	ABC-type proline glycine betaine transport system permease component
HAU86_RS19310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HAU86_RS19315	COG1116	anion transmembrane transporter activity
HAU86_RS19320	COG0129	dihydroxy-acid dehydratase activity
HAU86_RS19330	COG2084	Dehydrogenase
HAU86_RS19335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HAU86_RS19375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HAU86_RS19395	COG0454	-acetyltransferase
HAU86_RS19420	COG2200	EAL domain
HAU86_RS19460	COG2197	response regulator
HAU86_RS19480	COG0010	Belongs to the arginase family
HAU86_RS19490	COG5001	Diguanylate cyclase
HAU86_RS19490	COG3300	MHYT domain
HAU86_RS19510	COG2010	Cytochrome c
HAU86_RS19580	COG1301	dicarboxylic acid transport
HAU86_RS19640	COG2080	2 iron, 2 sulfur cluster binding
HAU86_RS19640	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HAU86_RS19680	COG0235	Class ii aldolase
HAU86_RS19685	COG2095	MarC family integral membrane protein
HAU86_RS19705	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HAU86_RS19720	COG0183	Belongs to the thiolase family
HAU86_RS19725	COG2723	6-phospho-beta-galactosidase activity
HAU86_RS19745	COG4771	TonB-dependent receptor
HAU86_RS19755	COG2197	response regulator
HAU86_RS19760	COG3851	Histidine kinase
HAU86_RS19765	COG2197	response regulator
HAU86_RS19770	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HAU86_RS19790	COG1131	(ABC) transporter
HAU86_RS19845	COG1116	anion transmembrane transporter activity
HAU86_RS19920	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HAU86_RS19925	COG3791	Glutathione-dependent formaldehyde-activating
HAU86_RS19945	COG2801	Transposase and inactivated derivatives
HAU86_RS19945	COG3415	Transposase
HAU86_RS19955	COG0723	plastoquinol--plastocyanin reductase activity
HAU86_RS19965	COG1250	3-hydroxyacyl-CoA dehydrogenase
HAU86_RS20050	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HAU86_RS20055	COG2986	histidine ammonia-lyase
HAU86_RS20060	COG1228	amidohydrolase
HAU86_RS20080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HAU86_RS20085	COG1116	anion transmembrane transporter activity
HAU86_RS20095	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HAU86_RS20115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAU86_RS20120	COG1136	(ABC) transporter
HAU86_RS20120	COG0577	efflux transmembrane transporter activity
HAU86_RS20125	COG0745	RESPONSE REGULATOR receiver
HAU86_RS20130	COG2205	protein histidine kinase activity
HAU86_RS20135	COG2223	nitrite transmembrane transporter activity
HAU86_RS20145	COG0656	L-ascorbic acid biosynthetic process
HAU86_RS20155	COG1566	PFAM secretion protein HlyD family protein
HAU86_RS20165	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HAU86_RS20175	COG1764	response to oxidative stress
HAU86_RS20185	COG0596	Alpha beta hydrolase
HAU86_RS20210	COG2267	carboxylic ester hydrolase activity
HAU86_RS20215	COG0596	Alpha beta hydrolase
HAU86_RS20225	COG2169	Transcriptional regulator
HAU86_RS20245	COG3685	Protein conserved in bacteria
HAU86_RS20280	COG5564	TIM-barrel signal transduction protein
HAU86_RS20285	COG2268	Band 7 protein
HAU86_RS20285	COG2268	Band 7 protein
HAU86_RS20330	COG3618	amidohydrolase
HAU86_RS20340	COG3386	PFAM SMP-30 Gluconolaconase
HAU86_RS20345	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HAU86_RS20360	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HAU86_RS20370	COG0531	amino acid
HAU86_RS20375	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS20385	COG0235	Class ii aldolase
HAU86_RS20405	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HAU86_RS20415	COG3842	ATPase activity
HAU86_RS20420	COG1176	ABC-type spermidine putrescine transport system, permease component I
HAU86_RS20430	COG1414	Transcriptional regulator
HAU86_RS20440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAU86_RS20455	COG0577	efflux transmembrane transporter activity
HAU86_RS20455	COG1136	(ABC) transporter
HAU86_RS20480	COG3321	synthase
HAU86_RS20480	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS20480	COG0604	alcohol dehydrogenase
HAU86_RS20500	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HAU86_RS20505	COG1902	pentaerythritol trinitrate reductase activity
HAU86_RS20520	COG1902	pentaerythritol trinitrate reductase activity
HAU86_RS20535	COG1024	Enoyl-CoA hydratase
HAU86_RS20540	COG1960	acyl-CoA dehydrogenase activity
HAU86_RS20550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HAU86_RS20590	COG1024	Enoyl-CoA hydratase
HAU86_RS20605	COG0517	IMP dehydrogenase activity
HAU86_RS20605	COG0516	GMP reductase activity
HAU86_RS20625	COG0778	Nitroreductase
HAU86_RS20650	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HAU86_RS20650	COG0574	Belongs to the PEP-utilizing enzyme family
HAU86_RS20660	COG2723	6-phospho-beta-galactosidase activity
HAU86_RS20665	COG0837	glucose binding
HAU86_RS20690	COG4178	(ABC) transporter
HAU86_RS20695	COG4178	(ABC) transporter
HAU86_RS20710	COG0071	Belongs to the small heat shock protein (HSP20) family
HAU86_RS20750	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HAU86_RS20800	COG0673	inositol 2-dehydrogenase activity
HAU86_RS20805	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HAU86_RS20815	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HAU86_RS20820	COG0297	glycogen (starch) synthase activity
HAU86_RS20825	COG4095	Psort location CytoplasmicMembrane, score
HAU86_RS20830	COG3384	dioxygenase
HAU86_RS20850	COG2072	flavoprotein involved in K transport
HAU86_RS20870	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HAU86_RS20875	COG0281	malic enzyme
HAU86_RS20880	COG0668	transmembrane transport
HAU86_RS20885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HAU86_RS20890	COG2326	polyphosphate kinase activity
HAU86_RS20950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HAU86_RS20960	COG0517	IMP dehydrogenase activity
HAU86_RS20960	COG1125	glycine betaine transport
HAU86_RS20965	COG1174	glycine betaine transport
HAU86_RS20990	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS20995	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HAU86_RS21015	COG0440	acetolactate synthase activity
HAU86_RS21020	COG0028	Belongs to the TPP enzyme family
HAU86_RS21025	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HAU86_RS21045	COG0330	HflC and HflK could
HAU86_RS21050	COG0330	HflC and HflK could
HAU86_RS21065	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HAU86_RS21105	COG0114	fumarate hydratase activity
HAU86_RS21160	COG3258	Cytochrome c
HAU86_RS21175	COG2202	Pas domain
HAU86_RS21175	COG3920	Histidine kinase
HAU86_RS21180	COG4191	Histidine kinase
HAU86_RS21180	COG0784	Response regulator, receiver
HAU86_RS21200	COG2124	cytochrome p450
HAU86_RS21205	COG1309	transcriptional regulator
HAU86_RS21240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HAU86_RS21245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HAU86_RS21250	COG2199	diguanylate cyclase activity
HAU86_RS21250	COG2202	Pas domain
HAU86_RS21250	COG2200	EAL domain
HAU86_RS21255	COG2271	Major facilitator Superfamily
HAU86_RS21260	COG3300	MHYT domain
HAU86_RS21260	COG5001	Diguanylate cyclase
HAU86_RS21270	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HAU86_RS21280	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HAU86_RS21300	COG0277	FAD linked oxidase domain protein
HAU86_RS21310	COG5487	UPF0391 membrane protein
HAU86_RS21315	COG0210	DNA helicase
HAU86_RS21360	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
HAU86_RS21380	COG2267	carboxylic ester hydrolase activity
HAU86_RS21390	COG1131	(ABC) transporter
HAU86_RS21395	COG0842	Transport permease protein
HAU86_RS21415	COG0584	glycerophosphoryl diester phosphodiesterase
HAU86_RS21435	COG2264	protein methyltransferase activity
HAU86_RS21445	COG0006	proline dipeptidase activity
HAU86_RS21445	COG0006	proline dipeptidase activity
HAU86_RS21450	COG2814	Major facilitator Superfamily
HAU86_RS21455	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HAU86_RS21465	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HAU86_RS21475	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HAU86_RS21480	COG0849	cell division
HAU86_RS21485	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HAU86_RS21490	COG1181	Belongs to the D-alanine--D-alanine ligase family
HAU86_RS21495	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HAU86_RS21500	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HAU86_RS21505	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HAU86_RS21520	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HAU86_RS21525	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HAU86_RS21530	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HAU86_RS21535	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HAU86_RS21550	COG0275	rRNA processing
HAU86_RS21555	COG3023	N-Acetylmuramoyl-L-alanine amidase
HAU86_RS21565	COG3795	YCII-related domain
HAU86_RS21580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HAU86_RS21600	COG5265	(ABC) transporter
HAU86_RS21615	COG1309	transcriptional regulator
HAU86_RS21635	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HAU86_RS21640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HAU86_RS21645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HAU86_RS21675	COG0688	phosphatidylethanolamine metabolic process
HAU86_RS21680	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HAU86_RS21700	COG1376	ErfK ybiS ycfS ynhG family protein
HAU86_RS21700	COG1388	LysM domain
HAU86_RS21710	COG2827	Endonuclease containing a URI domain
HAU86_RS21740	COG3842	ATPase activity
HAU86_RS21750	COG1176	ABC-type spermidine putrescine transport system, permease component I
HAU86_RS21775	COG0745	RESPONSE REGULATOR receiver
HAU86_RS21780	COG2205	protein histidine kinase activity
HAU86_RS21805	COG2022	thiamine diphosphate biosynthetic process
HAU86_RS21815	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HAU86_RS21835	COG0625	glutathione transferase activity
HAU86_RS21870	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS21875	COG2204	response regulator
HAU86_RS21900	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HAU86_RS21960	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HAU86_RS21965	COG1376	ErfK ybiS ycfS ynhG family protein
HAU86_RS21975	COG2897	thiosulfate sulfurtransferase activity
HAU86_RS21980	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HAU86_RS21995	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HAU86_RS22010	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
HAU86_RS22025	COG4948	Mandelate Racemase Muconate Lactonizing
HAU86_RS22055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HAU86_RS22060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HAU86_RS22065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HAU86_RS22070	COG0601	transmembrane transport
HAU86_RS22085	COG4191	Histidine kinase
HAU86_RS22085	COG0784	Response regulator, receiver
HAU86_RS22100	COG2072	flavoprotein involved in K transport
HAU86_RS22130	COG0475	glutathione-regulated potassium exporter activity
HAU86_RS22150	COG4948	Mandelate Racemase Muconate Lactonizing
HAU86_RS22160	COG0386	Belongs to the glutathione peroxidase family
HAU86_RS22165	COG0154	amidase activity
HAU86_RS22180	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HAU86_RS22185	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
HAU86_RS22190	COG0535	radical SAM domain protein
HAU86_RS22195	COG0535	radical SAM domain protein
HAU86_RS22215	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HAU86_RS22215	COG0674	pyruvate-flavodoxin oxidoreductase activity
HAU86_RS22220	COG1013	pyruvate-flavodoxin oxidoreductase activity
HAU86_RS22265	COG2719	SpoVR family
HAU86_RS22270	COG2718	Belongs to the UPF0229 family
HAU86_RS22275	COG2766	serine protein kinase
HAU86_RS22285	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HAU86_RS22290	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
HAU86_RS22295	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HAU86_RS22300	COG0363	glucosamine-6-phosphate deaminase activity
HAU86_RS22305	COG3265	gluconokinase activity
HAU86_RS22315	COG3387	PFAM Glycoside hydrolase 15-related
HAU86_RS22320	COG1640	4-alpha-glucanotransferase
HAU86_RS22325	COG0366	Alpha amylase catalytic
HAU86_RS22330	COG0366	Alpha amylase catalytic
HAU86_RS22335	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HAU86_RS22345	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HAU86_RS22370	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HAU86_RS22380	COG2205	protein histidine kinase activity
HAU86_RS22385	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HAU86_RS22390	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HAU86_RS22395	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HAU86_RS22420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HAU86_RS22470	COG1749	Flagellar hook protein flgE
HAU86_RS22495	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HAU86_RS22500	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HAU86_RS22505	COG1595	DNA-templated transcription, initiation
HAU86_RS22525	COG0427	acetyl-CoA hydrolase
HAU86_RS22545	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
HAU86_RS22550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HAU86_RS22555	COG2030	dehydratase
HAU86_RS22585	COG1414	Transcriptional regulator
HAU86_RS22595	COG1609	Transcriptional regulator
HAU86_RS22605	COG1175	transmembrane transport
HAU86_RS22610	COG0395	ABC-type sugar transport system, permease component
HAU86_RS22615	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS22630	COG0028	Belongs to the TPP enzyme family
HAU86_RS22635	COG1794	racemase activity, acting on amino acids and derivatives
HAU86_RS22660	COG0412	Dienelactone hydrolase
HAU86_RS22700	COG1684	flagellar biosynthetic protein fliR
HAU86_RS22705	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HAU86_RS22710	COG4794	Type iii secretion
HAU86_RS22715	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HAU86_RS22720	COG5443	negative regulation of bacterial-type flagellum assembly
HAU86_RS22740	COG1749	Flagellar hook protein flgE
HAU86_RS22760	COG1360	Flagellar Motor Protein
HAU86_RS22775	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HAU86_RS22780	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HAU86_RS22785	COG1338	Plays a role in the flagellum-specific transport system
HAU86_RS22795	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HAU86_RS22805	COG1706	bacterial-type flagellum-dependent cell motility
HAU86_RS22815	COG4786	Flagellar basal body rod
HAU86_RS22820	COG1677	Flagellar hook-basal body complex protein FliE
HAU86_RS22825	COG1558	bacterial-type flagellum-dependent cell motility
HAU86_RS22830	COG1815	bacterial-type flagellum-dependent cell motility
HAU86_RS22835	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HAU86_RS22840	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HAU86_RS22845	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HAU86_RS22860	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HAU86_RS22870	COG4786	Flagellar basal body rod
HAU86_RS22875	COG1157	protein secretion by the type III secretion system
HAU86_RS22880	COG1846	Transcriptional regulator
HAU86_RS22905	COG0411	ABC transporter
HAU86_RS22910	COG0559	Belongs to the binding-protein-dependent transport system permease family
HAU86_RS22930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HAU86_RS22960	COG1404	Belongs to the peptidase S8 family
HAU86_RS23010	COG0482	sulfurtransferase activity
HAU86_RS23020	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HAU86_RS23030	COG1766	The M ring may be actively involved in energy transduction
HAU86_RS23035	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HAU86_RS23045	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HAU86_RS23050	COG2204	response regulator
HAU86_RS23055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HAU86_RS23065	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HAU86_RS23080	COG1376	ErfK ybiS ycfS ynhG family protein
HAU86_RS23085	COG0745	RESPONSE REGULATOR receiver
HAU86_RS23100	COG2207	Transcriptional regulator
HAU86_RS23135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HAU86_RS23150	COG0243	molybdopterin cofactor binding
HAU86_RS23155	COG3043	anaerobic respiration
HAU86_RS23160	COG3005	denitrification pathway
HAU86_RS23170	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HAU86_RS23185	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HAU86_RS23190	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HAU86_RS23235	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HAU86_RS23240	COG1136	(ABC) transporter
HAU86_RS23245	COG4591	ABC-type transport system involved in lipoprotein release permease component
HAU86_RS23250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAU86_RS23255	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HAU86_RS23280	COG0840	transmembrane signaling receptor activity
HAU86_RS23285	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HAU86_RS23295	COG1175	transmembrane transport
HAU86_RS23300	COG0395	ABC-type sugar transport system, permease component
HAU86_RS23305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HAU86_RS23320	COG0848	biopolymer transport protein
HAU86_RS23330	COG3721	Heme iron utilization protein
HAU86_RS23350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HAU86_RS23355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAU86_RS23360	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
HAU86_RS23370	COG4566	intracellular signal transduction
HAU86_RS23395	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HAU86_RS23435	COG1175	transmembrane transport
HAU86_RS23445	COG1177	transmembrane transport
HAU86_RS23450	COG1176	ABC-type spermidine putrescine transport system, permease component I
HAU86_RS23455	COG3842	ATPase activity
HAU86_RS23465	COG3300	MHYT domain
HAU86_RS23465	COG5001	Diguanylate cyclase
HAU86_RS23470	COG0579	oxidoreductase
HAU86_RS23495	COG3447	MASE1 domain protein
HAU86_RS23495	COG5001	Diguanylate cyclase
HAU86_RS23495	COG5002	protein histidine kinase activity
HAU86_RS23500	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HAU86_RS23505	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HAU86_RS23510	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HAU86_RS23515	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HAU86_RS23535	COG0387	Pfam Sodium calcium exchanger
HAU86_RS23585	COG1164	Oligoendopeptidase f
HAU86_RS23590	COG2204	response regulator
HAU86_RS23595	COG2989	Protein conserved in bacteria
HAU86_RS23610	COG3750	Belongs to the UPF0335 family
HAU86_RS23625	COG0469	pyruvate kinase activity
HAU86_RS23630	COG1309	transcriptional regulator
HAU86_RS23675	COG0463	Glycosyl transferase, family 2
HAU86_RS23680	COG2226	methyltransferase
HAU86_RS23690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HAU86_RS23695	COG0037	tRNA processing
HAU86_RS23705	COG2885	chlorophyll binding
HAU86_RS23715	COG5001	Diguanylate cyclase
HAU86_RS23720	COG0823	Involved in the tonB-independent uptake of proteins
HAU86_RS23740	COG1045	serine acetyltransferase
HAU86_RS23780	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS23805	COG4941	Belongs to the sigma-70 factor family
HAU86_RS23810	COG3795	YCII-related domain
HAU86_RS23820	COG1309	transcriptional regulator
HAU86_RS23825	COG0625	glutathione transferase activity
HAU86_RS23830	COG0840	transmembrane signaling receptor activity
HAU86_RS23865	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HAU86_RS23880	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS23885	COG2233	PERMEase
HAU86_RS23890	COG1301	dicarboxylic acid transport
HAU86_RS23895	COG0488	(ABC) transporter
HAU86_RS23925	COG1177	transmembrane transport
HAU86_RS23930	COG1176	ABC-type spermidine putrescine transport system, permease component I
HAU86_RS23935	COG3842	ATPase activity
HAU86_RS23950	COG0402	S-adenosylhomocysteine deaminase activity
HAU86_RS23970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HAU86_RS23975	COG1126	abc transporter atp-binding protein
HAU86_RS24000	COG0519	Catalyzes the synthesis of GMP from XMP
HAU86_RS24000	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HAU86_RS24010	COG0824	Thioesterase
HAU86_RS24015	COG1408	metallophosphoesterase
HAU86_RS24020	COG2255	four-way junction helicase activity
HAU86_RS24025	COG0632	four-way junction helicase activity
HAU86_RS24030	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HAU86_RS24035	COG0217	transcriptional regulatory protein
HAU86_RS24075	COG1692	metallophosphoesterase
HAU86_RS24110	COG0126	phosphoglycerate kinase activity
HAU86_RS24120	COG3588	fructose-bisphosphate aldolase
HAU86_RS24135	COG0483	inositol monophosphate 1-phosphatase activity
HAU86_RS24140	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HAU86_RS24150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAU86_RS24155	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HAU86_RS24180	COG0659	secondary active sulfate transmembrane transporter activity
HAU86_RS24185	COG1132	(ABC) transporter
HAU86_RS24190	COG0254	rRNA binding
HAU86_RS24205	COG0604	alcohol dehydrogenase
HAU86_RS24205	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS24205	COG3321	synthase
HAU86_RS24220	COG5001	Diguanylate cyclase
HAU86_RS24220	COG2203	Gaf domain
HAU86_RS24220	COG4251	negative regulation of phosphorylation
HAU86_RS24220	COG3706	GGDEF domain
HAU86_RS24225	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HAU86_RS24230	COG2951	lytic endotransglycosylase activity
HAU86_RS24240	COG3237	CsbD-like
HAU86_RS24245	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS24250	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS24260	COG3415	Transposase
HAU86_RS24260	COG2801	Transposase and inactivated derivatives
HAU86_RS24265	COG1678	Uncharacterized ACR, COG1678
HAU86_RS24280	COG0730	response to heat
HAU86_RS24285	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS24300	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HAU86_RS24305	COG4208	sulfate ABC transporter
HAU86_RS24310	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HAU86_RS24315	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HAU86_RS24320	COG0175	sulfate reduction
HAU86_RS24330	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HAU86_RS24340	COG1648	precorrin-2 dehydrogenase activity
HAU86_RS24340	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HAU86_RS24355	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HAU86_RS24375	COG1388	LysM domain
HAU86_RS24375	COG1376	ErfK ybiS ycfS ynhG family protein
HAU86_RS24410	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HAU86_RS24415	COG0830	nickel cation binding
HAU86_RS24435	COG0804	urea catabolic process
HAU86_RS24440	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HAU86_RS24445	COG0832	Belongs to the urease beta subunit family
HAU86_RS24450	COG0831	urea catabolic process
HAU86_RS24455	COG0829	nickel cation binding
HAU86_RS24485	COG0513	Belongs to the DEAD box helicase family
HAU86_RS24490	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HAU86_RS24495	COG1278	Cold shock
HAU86_RS24540	COG4964	Belongs to the GSP D family
HAU86_RS24580	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HAU86_RS24590	COG4172	Belongs to the ABC transporter superfamily
HAU86_RS24595	COG4239	(ABC) transporter, permease
HAU86_RS24600	COG4174	ABC transporter (Permease)
HAU86_RS24605	COG4166	transmembrane transport
HAU86_RS24610	COG4166	transmembrane transport
HAU86_RS24615	COG3474	cytochrome
HAU86_RS24620	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HAU86_RS24625	COG0077	Prephenate dehydratase
HAU86_RS24625	COG1605	Chorismate mutase
HAU86_RS24630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HAU86_RS24665	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HAU86_RS24670	COG2852	Protein conserved in bacteria
HAU86_RS24690	COG3415	Transposase
HAU86_RS24690	COG2801	Transposase and inactivated derivatives
HAU86_RS24700	COG1960	acyl-CoA dehydrogenase activity
HAU86_RS24705	COG0183	Belongs to the thiolase family
HAU86_RS24710	COG0318	PFAM AMP-dependent synthetase and ligase
HAU86_RS24715	COG1024	Enoyl-CoA hydratase
HAU86_RS24715	COG1250	3-hydroxyacyl-CoA dehydrogenase
HAU86_RS24735	COG0559	Belongs to the binding-protein-dependent transport system permease family
HAU86_RS24795	COG0583	DNA-binding transcription factor activity
HAU86_RS24830	COG1024	Enoyl-CoA hydratase
HAU86_RS24835	COG0300	oxidoreductase activity
HAU86_RS24835	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS24835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HAU86_RS24835	COG3321	synthase
HAU86_RS24835	COG0318	PFAM AMP-dependent synthetase and ligase
HAU86_RS24890	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HAU86_RS24905	COG2378	regulation of single-species biofilm formation
HAU86_RS24925	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HAU86_RS24930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HAU86_RS24940	COG0604	alcohol dehydrogenase
HAU86_RS24955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAU86_RS24960	COG0842	Transport permease protein
HAU86_RS24960	COG1129	ABC transporter
HAU86_RS24965	COG0842	Transport permease protein
HAU86_RS24990	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HAU86_RS25015	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS25025	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS25040	COG0179	Fumarylacetoacetate (FAA) hydrolase
HAU86_RS25050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HAU86_RS25055	COG2267	carboxylic ester hydrolase activity
HAU86_RS25070	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HAU86_RS25075	COG1960	acyl-CoA dehydrogenase activity
HAU86_RS25080	COG4221	oxidoreductase activity
HAU86_RS25085	COG1024	Enoyl-CoA hydratase
HAU86_RS25100	COG0583	DNA-binding transcription factor activity
HAU86_RS25125	COG1546	Belongs to the CinA family
HAU86_RS25125	COG1058	Belongs to the CinA family
HAU86_RS25135	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HAU86_RS25140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAU86_RS25145	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
HAU86_RS25155	COG0444	Belongs to the ABC transporter superfamily
HAU86_RS25160	COG0154	amidase activity
HAU86_RS25170	COG4608	Belongs to the ABC transporter superfamily
HAU86_RS25175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HAU86_RS25185	COG0747	negative chemotaxis
HAU86_RS25190	COG0747	negative chemotaxis
HAU86_RS25280	COG2309	aminopeptidase activity
HAU86_RS25285	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HAU86_RS25310	COG2070	2-Nitropropane dioxygenase
HAU86_RS25320	COG0784	Response regulator, receiver
HAU86_RS25320	COG4191	Histidine kinase
HAU86_RS25325	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
HAU86_RS25340	COG1027	Aspartate ammonia-lyase
HAU86_RS25350	COG1238	metal cluster binding
HAU86_RS25355	COG0140	phosphoribosyl-ATP diphosphatase activity
HAU86_RS25370	COG1132	(ABC) transporter
HAU86_RS25375	COG1686	Belongs to the peptidase S11 family
HAU86_RS25380	COG0318	PFAM AMP-dependent synthetase and ligase
HAU86_RS25390	COG0678	peroxiredoxin activity
HAU86_RS25390	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HAU86_RS25395	COG0328	RNA-DNA hybrid ribonuclease activity
HAU86_RS25400	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HAU86_RS25405	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HAU86_RS25415	COG3047	cAMP biosynthetic process
HAU86_RS25450	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS25465	COG2358	TRAP transporter, solute receptor (TAXI family
HAU86_RS25495	COG0667	Aldo Keto reductase
HAU86_RS25510	COG4716	Myosin-crossreactive antigen
HAU86_RS25515	COG1022	Amp-dependent synthetase and ligase
HAU86_RS25520	COG1335	isochorismatase
HAU86_RS25555	COG1595	DNA-templated transcription, initiation
HAU86_RS25560	COG3806	Anti-sigma factor
HAU86_RS25565	COG1595	DNA-templated transcription, initiation
HAU86_RS25595	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HAU86_RS25605	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HAU86_RS25610	COG0424	maF-like protein
HAU86_RS25620	COG5328	Belongs to the UPF0262 family
HAU86_RS25625	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HAU86_RS25655	COG3634	alkyl hydroperoxide reductase activity
HAU86_RS25730	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HAU86_RS25755	COG2132	Multicopper oxidase
HAU86_RS25805	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HAU86_RS25840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HAU86_RS25855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HAU86_RS25870	COG3971	2-oxopent-4-enoate hydratase activity
HAU86_RS25875	COG0179	Fumarylacetoacetate (FAA) hydrolase
HAU86_RS25880	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HAU86_RS25885	COG3181	Tripartite tricarboxylate transporter family receptor
HAU86_RS25905	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS25915	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
HAU86_RS25920	COG3454	Phosphonate metabolism
HAU86_RS25925	COG4778	phosphonate C-P lyase system protein PhnL
HAU86_RS25930	COG4107	phosphonate C-P lyase system protein PhnK
HAU86_RS25935	COG3627	carbon phosphorus lyase activity
HAU86_RS25940	COG3626	phosphonate metabolism
HAU86_RS25945	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
HAU86_RS25950	COG3624	Phosphonate C-P lyase system protein PhnG
HAU86_RS25955	COG2188	Transcriptional regulator
HAU86_RS25960	COG3639	organic phosphonate transmembrane transporter activity
HAU86_RS25965	COG3639	organic phosphonate transmembrane transporter activity
HAU86_RS25975	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HAU86_RS25985	COG3454	Phosphonate metabolism
HAU86_RS25990	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
HAU86_RS26005	COG1024	Enoyl-CoA hydratase
HAU86_RS26015	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HAU86_RS26020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HAU86_RS26040	COG4774	siderophore transport
HAU86_RS26045	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HAU86_RS26050	COG0277	FAD linked oxidase domain protein
HAU86_RS26055	COG1802	Transcriptional regulator
HAU86_RS26075	COG1032	radical SAM domain protein
HAU86_RS26085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HAU86_RS26090	COG1116	anion transmembrane transporter activity
HAU86_RS26110	COG1959	2 iron, 2 sulfur cluster binding
HAU86_RS26135	COG0583	DNA-binding transcription factor activity
HAU86_RS26140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HAU86_RS26170	COG0730	response to heat
HAU86_RS26175	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HAU86_RS26180	COG0640	Transcriptional regulator
HAU86_RS26210	COG1376	ErfK ybiS ycfS ynhG family protein
HAU86_RS26210	COG1388	LysM domain
HAU86_RS26235	COG2391	methyltransferase activity
HAU86_RS26250	COG2264	protein methyltransferase activity
HAU86_RS26270	COG0720	synthase
HAU86_RS26280	COG3852	Histidine kinase
HAU86_RS26285	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HAU86_RS26295	COG0706	membrane insertase activity
HAU86_RS26300	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HAU86_RS26310	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HAU86_RS26325	COG2171	N-acyltransferase activity
HAU86_RS26335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HAU86_RS26340	COG0101	tRNA pseudouridine synthase activity
HAU86_RS26345	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HAU86_RS26350	COG0242	peptide deformylase activity
HAU86_RS26360	COG3415	Transposase
HAU86_RS26360	COG2801	Transposase and inactivated derivatives
HAU86_RS26370	COG2223	nitrite transmembrane transporter activity
HAU86_RS26380	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HAU86_RS26385	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HAU86_RS26390	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HAU86_RS26405	COG0765	amino acid transport
HAU86_RS26435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HAU86_RS26440	COG1522	sequence-specific DNA binding
HAU86_RS26445	COG2205	protein histidine kinase activity
HAU86_RS26450	COG0745	RESPONSE REGULATOR receiver
HAU86_RS26470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HAU86_RS26475	COG3577	Aspartyl protease
HAU86_RS26480	COG1643	Atp-dependent helicase
HAU86_RS26485	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HAU86_RS26495	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HAU86_RS26495	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HAU86_RS26500	COG1280	lysine exporter protein (LysE YggA)
HAU86_RS26505	COG3415	Transposase
HAU86_RS26505	COG2801	Transposase and inactivated derivatives
HAU86_RS26510	COG0625	glutathione transferase activity
HAU86_RS26515	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HAU86_RS26540	COG1201	RNA secondary structure unwinding
HAU86_RS26550	COG0251	oxidation-reduction process
HAU86_RS26570	COG1999	signal sequence binding
HAU86_RS26580	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
HAU86_RS26600	COG0167	dihydroorotate dehydrogenase activity
HAU86_RS26610	COG1234	tRNA 3'-trailer cleavage
HAU86_RS26655	COG1172	Belongs to the binding-protein-dependent transport system permease family
HAU86_RS26660	COG1129	ABC transporter
HAU86_RS26665	COG2115	Belongs to the xylose isomerase family
HAU86_RS26670	COG1070	Carbohydrate kinase
HAU86_RS26690	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HAU86_RS26730	COG4191	Histidine kinase
HAU86_RS26735	COG0717	Belongs to the dCTP deaminase family
HAU86_RS26760	COG2967	ApaG domain
HAU86_RS26770	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HAU86_RS26775	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HAU86_RS26785	COG0745	RESPONSE REGULATOR receiver
HAU86_RS26790	COG0704	Plays a role in the regulation of phosphate uptake
HAU86_RS26795	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HAU86_RS26800	COG0581	inorganic phosphate transmembrane transporter activity
HAU86_RS26805	COG0573	inorganic phosphate transmembrane transporter activity
HAU86_RS26810	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HAU86_RS26815	COG5002	protein histidine kinase activity
HAU86_RS26860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HAU86_RS26865	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HAU86_RS26890	COG4651	solute:proton antiporter activity
HAU86_RS26890	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HAU86_RS26895	COG1414	Transcriptional regulator
HAU86_RS26900	COG4638	Rieske (2fe-2S)
HAU86_RS26910	COG0477	Major facilitator Superfamily
HAU86_RS26950	COG3916	Acyl-homoserine-lactone synthase
HAU86_RS26955	COG2197	response regulator
HAU86_RS26970	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
HAU86_RS26975	COG4251	negative regulation of phosphorylation
HAU86_RS26980	COG3920	Histidine kinase
HAU86_RS26990	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HAU86_RS27005	COG1252	NADH dehydrogenase
HAU86_RS27015	COG2124	cytochrome p450
HAU86_RS27025	COG0318	PFAM AMP-dependent synthetase and ligase
HAU86_RS27040	COG1802	Transcriptional regulator
HAU86_RS27060	COG4172	Belongs to the ABC transporter superfamily
HAU86_RS27070	COG0601	transmembrane transport
HAU86_RS27075	COG0747	negative chemotaxis
HAU86_RS27110	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HAU86_RS27115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HAU86_RS27115	COG4191	Histidine kinase
HAU86_RS27120	COG0784	Response regulator, receiver
HAU86_RS27120	COG3437	response regulator, receiver
HAU86_RS27125	COG0745	RESPONSE REGULATOR receiver
HAU86_RS27130	COG1595	DNA-templated transcription, initiation
HAU86_RS27145	COG1271	oxidase subunit
HAU86_RS27150	COG1294	oxidase, subunit
HAU86_RS27170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HAU86_RS27175	COG1960	acyl-CoA dehydrogenase activity
HAU86_RS27180	COG1960	acyl-CoA dehydrogenase activity
HAU86_RS27190	COG2514	catechol 2,3-dioxygenase activity
HAU86_RS27200	COG2814	Major facilitator Superfamily
HAU86_RS27205	COG1505	serine-type exopeptidase activity
HAU86_RS27230	COG3258	Cytochrome c
HAU86_RS27240	COG0737	Belongs to the 5'-nucleotidase family
HAU86_RS27260	COG2271	Major facilitator Superfamily
HAU86_RS27270	COG2271	Major facilitator Superfamily
HAU86_RS27290	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HAU86_RS27295	COG0683	leucine binding
HAU86_RS27305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAU86_RS27325	COG0601	transmembrane transport
HAU86_RS27335	COG0444	Belongs to the ABC transporter superfamily
HAU86_RS27340	COG4608	Belongs to the ABC transporter superfamily
HAU86_RS27355	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HAU86_RS27360	COG3246	L-lysine catabolic process to acetate
HAU86_RS27375	COG1960	acyl-CoA dehydrogenase activity
HAU86_RS27380	COG1960	acyl-CoA dehydrogenase activity
HAU86_RS27420	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HAU86_RS27440	COG1129	ABC transporter
HAU86_RS27460	COG0784	Response regulator, receiver
HAU86_RS27460	COG2198	Histidine kinase
HAU86_RS27460	COG5002	protein histidine kinase activity
HAU86_RS27465	COG0745	RESPONSE REGULATOR receiver
HAU86_RS27485	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HAU86_RS27490	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HAU86_RS27495	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HAU86_RS27505	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HAU86_RS27515	COG5001	Diguanylate cyclase
HAU86_RS27515	COG3300	MHYT domain
HAU86_RS27535	COG5001	Diguanylate cyclase
HAU86_RS27535	COG3300	MHYT domain
HAU86_RS27550	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HAU86_RS27555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HAU86_RS27560	COG0142	geranyltranstransferase activity
HAU86_RS27590	COG0025	NhaP-type Na H and K H
HAU86_RS27610	COG2175	clavaminate synthase activity
HAU86_RS27615	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HAU86_RS27625	COG0735	belongs to the Fur family
HAU86_RS27635	COG1566	PFAM secretion protein HlyD family protein
HAU86_RS27640	COG2814	Major facilitator Superfamily
HAU86_RS27650	COG0840	transmembrane signaling receptor activity
HAU86_RS27655	COG0840	transmembrane signaling receptor activity
HAU86_RS27660	COG3485	protocatechuate 3,4-dioxygenase
HAU86_RS27665	COG3485	protocatechuate 3,4-dioxygenase
HAU86_RS27670	COG0183	Belongs to the thiolase family
HAU86_RS27675	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HAU86_RS27695	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HAU86_RS27725	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HAU86_RS27745	COG1131	(ABC) transporter
HAU86_RS27755	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
HAU86_RS27770	COG0366	Alpha amylase catalytic
HAU86_RS27775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HAU86_RS27780	COG1733	regulation of RNA biosynthetic process
HAU86_RS27810	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS27820	COG5001	Diguanylate cyclase
HAU86_RS27825	COG3829	transcription factor binding
HAU86_RS27825	COG3290	protein histidine kinase activity
HAU86_RS27835	COG0411	ABC transporter
HAU86_RS27855	COG5001	Diguanylate cyclase
HAU86_RS27860	COG3706	GGDEF domain
HAU86_RS27935	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HAU86_RS27950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HAU86_RS28000	COG0596	Alpha beta hydrolase
HAU86_RS28010	COG0412	Dienelactone hydrolase
HAU86_RS28040	COG0268	Binds directly to 16S ribosomal RNA
HAU86_RS28045	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HAU86_RS28055	COG3415	Transposase
HAU86_RS28055	COG2801	Transposase and inactivated derivatives
HAU86_RS28060	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HAU86_RS28075	COG3415	Transposase
HAU86_RS28075	COG2801	Transposase and inactivated derivatives
HAU86_RS28090	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HAU86_RS28095	COG0534	Mate efflux family protein
HAU86_RS28135	COG1741	Belongs to the pirin family
HAU86_RS28140	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HAU86_RS28165	COG0318	PFAM AMP-dependent synthetase and ligase
HAU86_RS28170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HAU86_RS28180	COG0180	Tryptophanyl-tRNA synthetase
HAU86_RS28190	COG3415	Transposase
HAU86_RS28190	COG2801	Transposase and inactivated derivatives
HAU86_RS28200	COG1214	PFAM Peptidase M22, glycoprotease
HAU86_RS28215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HAU86_RS28220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HAU86_RS28225	COG1702	phosphate starvation-inducible protein PhoH
HAU86_RS28230	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HAU86_RS28235	COG1253	flavin adenine dinucleotide binding
HAU86_RS28240	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HAU86_RS28245	COG1396	sequence-specific DNA binding
HAU86_RS28255	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HAU86_RS28265	COG0779	Required for maturation of 30S ribosomal subunits
HAU86_RS28280	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HAU86_RS28285	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HAU86_RS28290	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HAU86_RS28295	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HAU86_RS28300	COG1185	polyribonucleotide nucleotidyltransferase activity
HAU86_RS28310	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
HAU86_RS28330	COG0625	glutathione transferase activity
HAU86_RS28335	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HAU86_RS28345	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HAU86_RS28355	COG3415	Transposase
HAU86_RS28355	COG2801	Transposase and inactivated derivatives
HAU86_RS28375	COG0667	Aldo Keto reductase
HAU86_RS28380	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HAU86_RS28405	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HAU86_RS28410	COG2226	methyltransferase
HAU86_RS28415	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HAU86_RS28420	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HAU86_RS28425	COG0756	dUTP diphosphatase activity
HAU86_RS28430	COG2205	protein histidine kinase activity
HAU86_RS28435	COG3178	'Phosphotransferase
HAU86_RS28445	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HAU86_RS28455	COG1074	ATP-dependent DNA helicase activity
HAU86_RS28465	COG1793	dna ligase
HAU86_RS28475	COG0285	dihydrofolate synthase activity
HAU86_RS28480	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HAU86_RS28485	COG0159	tryptophan synthase activity
HAU86_RS28490	COG0133	tryptophan synthase activity
HAU86_RS28495	COG0135	phosphoribosylanthranilate isomerase activity
HAU86_RS28505	COG0776	regulation of translation
HAU86_RS28510	COG0616	signal peptide processing
HAU86_RS28515	COG0539	negative regulation of cytoplasmic translation
HAU86_RS28520	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HAU86_RS28525	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HAU86_RS28545	COG1846	Transcriptional regulator
HAU86_RS28550	COG1764	response to oxidative stress
HAU86_RS28570	COG0395	ABC-type sugar transport system, permease component
HAU86_RS28575	COG3842	ATPase activity
HAU86_RS28580	COG0071	Belongs to the small heat shock protein (HSP20) family
HAU86_RS28590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HAU86_RS28595	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HAU86_RS28600	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HAU86_RS28605	COG1137	ATPase activity
HAU86_RS28610	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HAU86_RS28625	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HAU86_RS28630	COG2814	Major facilitator Superfamily
HAU86_RS28655	COG0277	FAD linked oxidase domain protein
HAU86_RS28660	COG1968	undecaprenyl-diphosphatase activity
HAU86_RS28670	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HAU86_RS28690	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HAU86_RS28700	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HAU86_RS28705	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HAU86_RS28710	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HAU86_RS28715	COG2852	Protein conserved in bacteria
HAU86_RS28720	COG0072	phenylalanine-tRNA ligase activity
HAU86_RS28720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HAU86_RS28740	COG1937	Protein conserved in bacteria
HAU86_RS28750	COG0864	Transcriptional regulator
HAU86_RS28770	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HAU86_RS28780	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HAU86_RS28785	COG0588	phosphoglycerate mutase activity
HAU86_RS28790	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HAU86_RS28800	COG0284	orotidine-5'-phosphate decarboxylase activity
HAU86_RS28805	COG0431	NADPH-dependent FMN reductase
HAU86_RS28810	COG3963	phosphatidate phosphatase activity
HAU86_RS28815	COG0484	heat shock protein binding
HAU86_RS28820	COG0443	Heat shock 70 kDa protein
HAU86_RS28830	COG1335	isochorismatase
HAU86_RS28835	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HAU86_RS28840	COG1420	regulation of RNA biosynthetic process
HAU86_RS28845	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HAU86_RS28850	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HAU86_RS28855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HAU86_RS28865	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HAU86_RS28870	COG0792	nuclease activity
HAU86_RS28875	COG0189	ligase activity
HAU86_RS28885	COG4964	Belongs to the GSP D family
HAU86_RS28925	COG0628	permease
HAU86_RS28935	COG1072	(Pantothenic acid kinase))
HAU86_RS28940	COG0140	phosphoribosyl-ATP diphosphatase activity
HAU86_RS28945	COG0107	imidazoleglycerol-phosphate synthase activity
HAU86_RS28950	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HAU86_RS28955	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HAU86_RS28965	COG0131	Imidazoleglycerol-phosphate dehydratase
HAU86_RS28970	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HAU86_RS28980	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HAU86_RS28995	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HAU86_RS29005	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
HAU86_RS29010	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HAU86_RS29015	COG0237	dephospho-CoA kinase activity
HAU86_RS29020	COG0424	maF-like protein
HAU86_RS29025	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
HAU86_RS29035	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HAU86_RS29040	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HAU86_RS29045	COG0445	tRNA wobble uridine modification
HAU86_RS29050	COG0357	Ribosomal RNA small subunit methyltransferase G
HAU86_RS29075	COG0495	leucyl-tRNA aminoacylation
HAU86_RS29080	COG3706	GGDEF domain
HAU86_RS29085	COG5001	Diguanylate cyclase
HAU86_RS29085	COG4251	negative regulation of phosphorylation
HAU86_RS29085	COG2203	Gaf domain
HAU86_RS29085	COG3706	GGDEF domain
HAU86_RS29090	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HAU86_RS29105	COG0745	RESPONSE REGULATOR receiver
HAU86_RS29120	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HAU86_RS29125	COG1674	ftsk spoiiie
HAU86_RS29130	COG0436	Aminotransferase
HAU86_RS29140	COG0004	ammonium transporteR
HAU86_RS29145	COG0347	Belongs to the P(II) protein family
HAU86_RS29150	COG0004	ammonium transporteR
HAU86_RS29155	COG0347	Belongs to the P(II) protein family
HAU86_RS29170	COG1946	Acyl-CoA thioesterase
HAU86_RS29175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HAU86_RS29180	COG2835	tetraacyldisaccharide 4'-kinase activity
HAU86_RS29205	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HAU86_RS29210	COG3118	belongs to the thioredoxin family
HAU86_RS29235	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HAU86_RS29245	COG0534	Mate efflux family protein
HAU86_RS29260	COG2814	Major facilitator Superfamily
HAU86_RS29265	COG0405	Gamma-glutamyltransferase
HAU86_RS29275	COG0138	bifunctional purine biosynthesis protein purh
HAU86_RS29300	COG1376	ErfK ybiS ycfS ynhG family protein
HAU86_RS29305	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HAU86_RS29320	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HAU86_RS29325	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HAU86_RS29360	COG0726	polysaccharide deacetylase
HAU86_RS29375	COG2814	Major facilitator Superfamily
HAU86_RS29400	COG4221	oxidoreductase activity
HAU86_RS29405	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HAU86_RS29410	COG1024	Enoyl-CoA hydratase
HAU86_RS29430	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HAU86_RS29435	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HAU86_RS29440	COG1247	-acetyltransferase
HAU86_RS29450	COG3011	Protein conserved in bacteria
HAU86_RS29485	COG0784	Response regulator, receiver
HAU86_RS29500	COG2154	pterin-4-alpha-carbinolamine dehydratase
HAU86_RS29515	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS29525	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HAU86_RS29535	COG0671	phosphoesterase, PA-phosphatase related
HAU86_RS29540	COG0137	argininosuccinate synthase activity
HAU86_RS29610	COG0730	response to heat
HAU86_RS29620	COG0318	PFAM AMP-dependent synthetase and ligase
HAU86_RS29625	COG4221	oxidoreductase activity
HAU86_RS29630	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
HAU86_RS29635	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HAU86_RS29640	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HAU86_RS29650	COG0473	3-isopropylmalate dehydrogenase activity
HAU86_RS29670	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HAU86_RS29675	COG0288	reversible hydration of carbon dioxide
HAU86_RS29680	COG2301	Belongs to the HpcH HpaI aldolase family
HAU86_RS29685	COG4977	sequence-specific DNA binding
HAU86_RS29715	COG0066	3-isopropylmalate dehydratase activity
HAU86_RS29745	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HAU86_RS29750	COG0335	large ribosomal subunit rRNA binding
HAU86_RS29755	COG0336	Belongs to the RNA methyltransferase TrmD family
HAU86_RS29760	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HAU86_RS29765	COG0228	four-way junction DNA binding
HAU86_RS29770	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HAU86_RS29790	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HAU86_RS29795	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HAU86_RS29805	COG0564	pseudouridine synthase activity
HAU86_RS29810	COG0552	protein localization to endoplasmic reticulum
HAU86_RS29815	COG2917	probably involved in intracellular septation
HAU86_RS29820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HAU86_RS29830	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HAU86_RS29835	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HAU86_RS29840	COG4133	protoheme IX ABC transporter activity
HAU86_RS29845	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HAU86_RS29865	COG0670	Belongs to the BI1 family
HAU86_RS29870	COG0577	efflux transmembrane transporter activity
HAU86_RS29870	COG1136	(ABC) transporter
HAU86_RS29875	COG1136	(ABC) transporter
HAU86_RS29880	COG2755	lipolytic protein G-D-S-L family
HAU86_RS29885	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HAU86_RS29890	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HAU86_RS29895	COG0039	L-malate dehydrogenase activity
HAU86_RS29900	COG0045	succinate-CoA ligase (ADP-forming) activity
HAU86_RS29910	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HAU86_RS29920	COG0508	dehydrogenase complex catalyzes the overall conversion of
HAU86_RS29925	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS29930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HAU86_RS29945	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HAU86_RS29955	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HAU86_RS29960	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HAU86_RS29965	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HAU86_RS29970	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HAU86_RS29975	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HAU86_RS29980	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HAU86_RS29990	COG0494	nUDIX hydrolase
HAU86_RS29995	COG1051	belongs to the nudix hydrolase family
HAU86_RS30005	COG0793	Belongs to the peptidase S41A family
HAU86_RS30015	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HAU86_RS30020	COG0799	negative regulation of ribosome biogenesis
HAU86_RS30025	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HAU86_RS30030	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HAU86_RS30035	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HAU86_RS30045	COG4106	trans-aconitate 2-methyltransferase activity
HAU86_RS30065	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HAU86_RS30080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HAU86_RS30085	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HAU86_RS30090	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HAU86_RS30115	COG0697	spore germination
HAU86_RS30120	COG5001	Diguanylate cyclase
HAU86_RS30120	COG4251	negative regulation of phosphorylation
HAU86_RS30120	COG3706	GGDEF domain
HAU86_RS30120	COG2203	Gaf domain
HAU86_RS30165	COG0784	Response regulator, receiver
HAU86_RS30165	COG2198	Histidine kinase
HAU86_RS30165	COG0643	Histidine kinase
HAU86_RS30170	COG0835	chemotaxis
HAU86_RS30175	COG0745	RESPONSE REGULATOR receiver
HAU86_RS30190	COG2201	protein-glutamate methylesterase activity
HAU86_RS30200	COG4566	intracellular signal transduction
HAU86_RS30205	COG0784	Response regulator, receiver
HAU86_RS30205	COG4191	Histidine kinase
HAU86_RS30210	COG2204	response regulator
HAU86_RS30220	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HAU86_RS30235	COG1696	Membrane protein involved in D-alanine export
HAU86_RS30245	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HAU86_RS30275	COG2706	6-phosphogluconolactonase activity
HAU86_RS30290	COG5001	Diguanylate cyclase
HAU86_RS30310	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HAU86_RS30315	COG0179	Fumarylacetoacetate (FAA) hydrolase
HAU86_RS30325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HAU86_RS30345	COG1802	Transcriptional regulator
HAU86_RS30365	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HAU86_RS30400	COG1846	Transcriptional regulator
HAU86_RS30405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HAU86_RS30420	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
HAU86_RS30430	COG3813	Protein conserved in bacteria
HAU86_RS30435	COG1522	sequence-specific DNA binding
HAU86_RS30445	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HAU86_RS30475	COG0477	Major facilitator Superfamily
HAU86_RS30480	COG1877	trehalose-phosphatase activity
HAU86_RS30485	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
HAU86_RS30500	COG0583	DNA-binding transcription factor activity
HAU86_RS30505	COG2814	Major facilitator Superfamily
HAU86_RS30510	COG0154	amidase activity
HAU86_RS30515	COG2873	o-acetylhomoserine
HAU86_RS30530	COG0514	ATP-dependent DNA helicase (RecQ)
HAU86_RS30535	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HAU86_RS30540	COG1522	sequence-specific DNA binding
HAU86_RS30580	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
HAU86_RS30595	COG0697	spore germination
HAU86_RS30605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HAU86_RS30620	COG2890	protein-(glutamine-N5) methyltransferase activity
HAU86_RS30660	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HAU86_RS30665	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
HAU86_RS30670	COG0527	aspartate kinase activity
HAU86_RS30680	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HAU86_RS30695	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HAU86_RS30705	COG1040	competence protein
HAU86_RS30725	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HAU86_RS30730	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HAU86_RS30735	COG0653	protein targeting
HAU86_RS30770	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HAU86_RS30785	COG3034	peptidoglycan biosynthetic process
HAU86_RS30790	COG0825	malonyl-CoA metabolic process
HAU86_RS30795	COG4974	Belongs to the 'phage' integrase family
HAU86_RS30805	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HAU86_RS30810	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HAU86_RS30815	COG1253	flavin adenine dinucleotide binding
HAU86_RS30830	COG0372	Belongs to the citrate synthase family
HAU86_RS30835	COG0372	Belongs to the citrate synthase family
HAU86_RS30855	COG0586	Pfam SNARE associated Golgi protein
HAU86_RS30875	COG1902	pentaerythritol trinitrate reductase activity
HAU86_RS30930	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HAU86_RS30945	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HAU86_RS30950	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HAU86_RS30960	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
HAU86_RS30975	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HAU86_RS30980	COG1845	cytochrome c oxidase, subunit III
HAU86_RS30985	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HAU86_RS30990	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HAU86_RS30995	COG0477	Major facilitator Superfamily
HAU86_RS31015	COG1024	Enoyl-CoA hydratase
HAU86_RS31025	COG1024	Enoyl-CoA hydratase
HAU86_RS31030	COG1960	acyl-CoA dehydrogenase activity
HAU86_RS31045	COG2801	Transposase and inactivated derivatives
HAU86_RS31045	COG3415	Transposase
HAU86_RS31050	COG2261	transglycosylase associated protein
HAU86_RS31060	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HAU86_RS31080	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HAU86_RS31130	COG3964	amidohydrolase
HAU86_RS31140	COG2207	Transcriptional regulator
HAU86_RS31145	COG1960	acyl-CoA dehydrogenase activity
HAU86_RS31150	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS31160	COG2030	dehydratase
HAU86_RS31175	COG0318	PFAM AMP-dependent synthetase and ligase
HAU86_RS31185	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HAU86_RS31190	COG1024	Enoyl-CoA hydratase
HAU86_RS31200	COG0583	DNA-binding transcription factor activity
HAU86_RS31205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HAU86_RS31230	COG0625	glutathione transferase activity
HAU86_RS31260	COG2130	NADP-dependent
HAU86_RS31265	COG1301	dicarboxylic acid transport
HAU86_RS31270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HAU86_RS31285	COG0069	glutamate synthase activity
HAU86_RS31295	COG1253	flavin adenine dinucleotide binding
HAU86_RS31300	COG0840	transmembrane signaling receptor activity
HAU86_RS31305	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HAU86_RS31320	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HAU86_RS31330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HAU86_RS31335	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HAU86_RS31350	COG2003	Belongs to the UPF0758 family
HAU86_RS31355	COG0024	Methionine aminopeptidase
HAU86_RS31360	COG3264	Mechanosensitive ion channel
HAU86_RS31360	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
HAU86_RS31370	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HAU86_RS31375	COG4149	molybdate abc transporter
HAU86_RS31380	COG0725	ABC transporter, periplasmic molybdate-binding protein
HAU86_RS31385	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
HAU86_RS31390	COG5001	Diguanylate cyclase
HAU86_RS31400	COG1960	acyl-CoA dehydrogenase activity
HAU86_RS31420	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HAU86_RS31430	COG0481	GTPase activity
HAU86_RS31445	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HAU86_RS31445	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HAU86_RS31450	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HAU86_RS31455	COG2205	protein histidine kinase activity
HAU86_RS31460	COG0745	RESPONSE REGULATOR receiver
HAU86_RS31470	COG0583	DNA-binding transcription factor activity
HAU86_RS31480	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS31490	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HAU86_RS31505	COG0058	SHG alpha-glucan phosphorylase activity
HAU86_RS31510	COG0583	DNA-binding transcription factor activity
HAU86_RS31525	COG0730	response to heat
HAU86_RS31555	COG1960	acyl-CoA dehydrogenase activity
HAU86_RS31560	COG0183	Belongs to the thiolase family
HAU86_RS31565	COG1250	3-hydroxyacyl-CoA dehydrogenase
HAU86_RS31565	COG1024	Enoyl-CoA hydratase
HAU86_RS31575	COG0625	glutathione transferase activity
HAU86_RS31600	COG0681	Belongs to the peptidase S26 family
HAU86_RS31605	COG0312	modulator of DNA gyrase
HAU86_RS31615	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HAU86_RS31620	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HAU86_RS31625	COG0109	protoheme IX farnesyltransferase activity
HAU86_RS31635	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
HAU86_RS31650	COG3346	SURF1 family
HAU86_RS31675	COG0612	Peptidase, M16
HAU86_RS31680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HAU86_RS31690	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HAU86_RS31695	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HAU86_RS31705	COG0356	it plays a direct role in the translocation of protons across the membrane
HAU86_RS31720	COG0432	Pfam Uncharacterised protein family UPF0047
HAU86_RS31740	COG1764	response to oxidative stress
HAU86_RS31745	COG0596	Alpha beta hydrolase
HAU86_RS31755	COG0300	oxidoreductase activity
HAU86_RS31760	COG0784	Response regulator, receiver
HAU86_RS31760	COG2198	Histidine kinase
HAU86_RS31760	COG2205	protein histidine kinase activity
HAU86_RS31765	COG0156	8-amino-7-oxononanoate synthase activity
HAU86_RS31770	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HAU86_RS31775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HAU86_RS31815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HAU86_RS31825	COG0747	negative chemotaxis
HAU86_RS31840	COG0596	Alpha beta hydrolase
HAU86_RS31845	COG1309	transcriptional regulator
HAU86_RS31855	COG2020	methyltransferase activity
HAU86_RS31875	COG4585	Histidine kinase
HAU86_RS31905	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HAU86_RS31940	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HAU86_RS31940	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HAU86_RS31955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HAU86_RS31960	COG1473	amidohydrolase
HAU86_RS31970	COG0601	transmembrane transport
HAU86_RS31975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HAU86_RS31980	COG0444	Belongs to the ABC transporter superfamily
HAU86_RS31985	COG4608	Belongs to the ABC transporter superfamily
HAU86_RS31995	COG3360	Dodecin
HAU86_RS32005	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
HAU86_RS32005	COG2273	Hydrolase Family 16
HAU86_RS32035	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HAU86_RS32060	COG2086	electron transfer activity
HAU86_RS32065	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HAU86_RS32070	COG1250	3-hydroxyacyl-CoA dehydrogenase
HAU86_RS32080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HAU86_RS32085	COG0165	Argininosuccinate lyase
HAU86_RS32105	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HAU86_RS32120	COG2204	response regulator
HAU86_RS32130	COG2884	Cell division ATP-binding protein ftsE
HAU86_RS32160	COG0287	Prephenate dehydrogenase
HAU86_RS32165	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HAU86_RS32175	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HAU86_RS32180	COG2813	Specifically methylates the guanine in position
HAU86_RS32180	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HAU86_RS32200	COG0542	response to heat
HAU86_RS32210	COG0739	heme binding
HAU86_RS32245	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
HAU86_RS32255	COG5285	phytanoyl-CoA dioxygenase
HAU86_RS32260	COG2186	Transcriptional regulator
HAU86_RS32270	COG2267	carboxylic ester hydrolase activity
HAU86_RS32280	COG0318	PFAM AMP-dependent synthetase and ligase
HAU86_RS32310	COG1960	acyl-CoA dehydrogenase activity
HAU86_RS32315	COG1960	acyl-CoA dehydrogenase activity
HAU86_RS32320	COG1960	acyl-CoA dehydrogenase activity
HAU86_RS32325	COG0778	Nitroreductase
HAU86_RS32340	COG0784	Response regulator, receiver
HAU86_RS32355	COG0326	Molecular chaperone. Has ATPase activity
HAU86_RS32375	COG0318	PFAM AMP-dependent synthetase and ligase
HAU86_RS32425	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HAU86_RS32445	COG1121	(ABC) transporter
HAU86_RS32455	COG0803	Belongs to the bacterial solute-binding protein 9 family
HAU86_RS32460	COG0523	cobalamin synthesis protein
HAU86_RS32505	COG0339	signal peptide processing
HAU86_RS32515	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HAU86_RS32525	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HAU86_RS32535	COG0330	HflC and HflK could
HAU86_RS32570	COG3415	Transposase
HAU86_RS32570	COG2801	Transposase and inactivated derivatives
HAU86_RS32580	COG0069	glutamate synthase activity
HAU86_RS32580	COG0070	glutamate synthase
HAU86_RS32580	COG0067	glutamate synthase
HAU86_RS32595	COG0071	Belongs to the small heat shock protein (HSP20) family
HAU86_RS32605	COG2010	Cytochrome c
HAU86_RS32615	COG1280	lysine exporter protein (LysE YggA)
HAU86_RS32625	COG0583	DNA-binding transcription factor activity
HAU86_RS32700	COG2205	protein histidine kinase activity
HAU86_RS32705	COG0745	RESPONSE REGULATOR receiver
HAU86_RS32715	COG1472	Belongs to the glycosyl hydrolase 3 family
HAU86_RS32720	COG0747	negative chemotaxis
HAU86_RS32725	COG3546	catalase activity
HAU86_RS32755	COG1012	belongs to the aldehyde dehydrogenase family
HAU86_RS32760	COG1902	pentaerythritol trinitrate reductase activity
HAU86_RS32790	COG0765	amino acid transport
HAU86_RS32795	COG0765	amino acid transport
HAU86_RS32800	COG1126	abc transporter atp-binding protein
HAU86_RS32810	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HAU86_RS32825	COG0583	DNA-binding transcription factor activity
HAU86_RS32860	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HAU86_RS32870	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HAU86_RS32875	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
HAU86_RS32895	COG1215	transferase activity, transferring glycosyl groups
HAU86_RS32915	COG0655	NAD(P)H dehydrogenase (quinone) activity
HAU86_RS32920	COG1741	Belongs to the pirin family
HAU86_RS32925	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS32930	COG0583	DNA-binding transcription factor activity
HAU86_RS32950	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HAU86_RS32960	COG1733	regulation of RNA biosynthetic process
HAU86_RS32965	COG1028	Short-chain dehydrogenase reductase Sdr
HAU86_RS32975	COG0257	Belongs to the bacterial ribosomal protein bL36 family