locus-tag	class	description
CIT39_RS00030	COG1204	response to ionizing radiation
CIT39_RS00055	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CIT39_RS00060	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CIT39_RS00070	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CIT39_RS00085	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CIT39_RS00090	COG1845	cytochrome c oxidase, subunit III
CIT39_RS00095	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CIT39_RS00100	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CIT39_RS00105	COG0477	Major facilitator Superfamily
CIT39_RS00125	COG1024	Enoyl-CoA hydratase
CIT39_RS00135	COG1024	Enoyl-CoA hydratase
CIT39_RS00140	COG1960	acyl-CoA dehydrogenase activity
CIT39_RS00155	COG2261	transglycosylase associated protein
CIT39_RS00165	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CIT39_RS00185	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CIT39_RS00210	COG2271	Major facilitator Superfamily
CIT39_RS00220	COG3473	Maleate cis-trans isomerase
CIT39_RS00225	COG3964	amidohydrolase
CIT39_RS00235	COG2207	Transcriptional regulator
CIT39_RS00240	COG1960	acyl-CoA dehydrogenase activity
CIT39_RS00245	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS00255	COG2030	dehydratase
CIT39_RS00270	COG0318	PFAM AMP-dependent synthetase and ligase
CIT39_RS00280	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CIT39_RS00285	COG1024	Enoyl-CoA hydratase
CIT39_RS00295	COG0583	DNA-binding transcription factor activity
CIT39_RS00300	COG0492	ferredoxin-NADP+ reductase activity
CIT39_RS00325	COG0625	glutathione transferase activity
CIT39_RS00355	COG2130	NADP-dependent
CIT39_RS00360	COG1301	dicarboxylic acid transport
CIT39_RS00365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CIT39_RS00380	COG0069	glutamate synthase activity
CIT39_RS00390	COG1253	flavin adenine dinucleotide binding
CIT39_RS00400	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CIT39_RS00415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CIT39_RS00425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CIT39_RS00430	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIT39_RS00445	COG2003	Belongs to the UPF0758 family
CIT39_RS00450	COG0024	Methionine aminopeptidase
CIT39_RS00455	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CIT39_RS00455	COG3264	Mechanosensitive ion channel
CIT39_RS00465	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CIT39_RS00470	COG4149	molybdate abc transporter
CIT39_RS00475	COG0725	ABC transporter, periplasmic molybdate-binding protein
CIT39_RS00480	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
CIT39_RS00485	COG5001	Diguanylate cyclase
CIT39_RS00500	COG1960	acyl-CoA dehydrogenase activity
CIT39_RS00510	COG0477	Major facilitator Superfamily
CIT39_RS00525	COG0481	GTPase activity
CIT39_RS00540	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CIT39_RS00540	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CIT39_RS00550	COG2205	protein histidine kinase activity
CIT39_RS00555	COG0745	RESPONSE REGULATOR receiver
CIT39_RS00565	COG0583	DNA-binding transcription factor activity
CIT39_RS00575	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS00585	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CIT39_RS00595	COG0058	SHG alpha-glucan phosphorylase activity
CIT39_RS00600	COG0583	DNA-binding transcription factor activity
CIT39_RS00615	COG0730	response to heat
CIT39_RS00645	COG1960	acyl-CoA dehydrogenase activity
CIT39_RS00650	COG0183	Belongs to the thiolase family
CIT39_RS00655	COG1024	Enoyl-CoA hydratase
CIT39_RS00655	COG1250	3-hydroxyacyl-CoA dehydrogenase
CIT39_RS00690	COG0681	Belongs to the peptidase S26 family
CIT39_RS00695	COG0312	modulator of DNA gyrase
CIT39_RS00705	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CIT39_RS00710	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CIT39_RS00715	COG0109	protoheme IX farnesyltransferase activity
CIT39_RS00725	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CIT39_RS00740	COG3346	SURF1 family
CIT39_RS00765	COG0612	Peptidase, M16
CIT39_RS00770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CIT39_RS00780	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CIT39_RS00785	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CIT39_RS00795	COG0356	it plays a direct role in the translocation of protons across the membrane
CIT39_RS00815	COG0432	Pfam Uncharacterised protein family UPF0047
CIT39_RS00835	COG1764	response to oxidative stress
CIT39_RS00840	COG0596	Alpha beta hydrolase
CIT39_RS00850	COG0300	oxidoreductase activity
CIT39_RS00855	COG2205	protein histidine kinase activity
CIT39_RS00855	COG2198	Histidine kinase
CIT39_RS00855	COG0784	Response regulator, receiver
CIT39_RS00860	COG0156	8-amino-7-oxononanoate synthase activity
CIT39_RS00865	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CIT39_RS00910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CIT39_RS00920	COG0747	negative chemotaxis
CIT39_RS00935	COG0596	Alpha beta hydrolase
CIT39_RS00940	COG1309	transcriptional regulator
CIT39_RS00950	COG2020	methyltransferase activity
CIT39_RS00970	COG4585	Histidine kinase
CIT39_RS01000	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CIT39_RS01035	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CIT39_RS01035	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CIT39_RS01050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CIT39_RS01055	COG1473	amidohydrolase
CIT39_RS01065	COG0601	transmembrane transport
CIT39_RS01070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CIT39_RS01075	COG0444	Belongs to the ABC transporter superfamily
CIT39_RS01080	COG4608	Belongs to the ABC transporter superfamily
CIT39_RS01090	COG3360	Dodecin
CIT39_RS01100	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CIT39_RS01100	COG2273	Hydrolase Family 16
CIT39_RS01125	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CIT39_RS01150	COG2086	electron transfer activity
CIT39_RS01155	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CIT39_RS01160	COG1250	3-hydroxyacyl-CoA dehydrogenase
CIT39_RS01170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CIT39_RS01175	COG0165	Argininosuccinate lyase
CIT39_RS01185	COG0019	diaminopimelate decarboxylase activity
CIT39_RS01195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CIT39_RS01210	COG2204	response regulator
CIT39_RS01220	COG2884	Cell division ATP-binding protein ftsE
CIT39_RS01250	COG0287	Prephenate dehydrogenase
CIT39_RS01255	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CIT39_RS01265	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CIT39_RS01270	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CIT39_RS01270	COG2813	Specifically methylates the guanine in position
CIT39_RS01290	COG0542	response to heat
CIT39_RS01300	COG0739	heme binding
CIT39_RS01335	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CIT39_RS01345	COG5285	phytanoyl-CoA dioxygenase
CIT39_RS01350	COG2186	Transcriptional regulator
CIT39_RS01360	COG2267	carboxylic ester hydrolase activity
CIT39_RS01370	COG0318	PFAM AMP-dependent synthetase and ligase
CIT39_RS01405	COG1960	acyl-CoA dehydrogenase activity
CIT39_RS01410	COG1960	acyl-CoA dehydrogenase activity
CIT39_RS01415	COG1960	acyl-CoA dehydrogenase activity
CIT39_RS01420	COG0778	Nitroreductase
CIT39_RS01435	COG0784	Response regulator, receiver
CIT39_RS01450	COG0326	Molecular chaperone. Has ATPase activity
CIT39_RS01470	COG0318	PFAM AMP-dependent synthetase and ligase
CIT39_RS01520	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CIT39_RS01540	COG1121	(ABC) transporter
CIT39_RS01550	COG0803	Belongs to the bacterial solute-binding protein 9 family
CIT39_RS01555	COG0523	cobalamin synthesis protein
CIT39_RS01580	COG0251	oxidation-reduction process
CIT39_RS01615	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CIT39_RS01625	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CIT39_RS01635	COG0330	HflC and HflK could
CIT39_RS01675	COG0070	glutamate synthase
CIT39_RS01675	COG0069	glutamate synthase activity
CIT39_RS01675	COG0067	glutamate synthase
CIT39_RS01690	COG0071	Belongs to the small heat shock protein (HSP20) family
CIT39_RS01700	COG2010	Cytochrome c
CIT39_RS01710	COG1280	lysine exporter protein (LysE YggA)
CIT39_RS01720	COG0583	DNA-binding transcription factor activity
CIT39_RS01795	COG2205	protein histidine kinase activity
CIT39_RS01800	COG0745	RESPONSE REGULATOR receiver
CIT39_RS01810	COG1472	Belongs to the glycosyl hydrolase 3 family
CIT39_RS01815	COG0747	negative chemotaxis
CIT39_RS01820	COG3546	catalase activity
CIT39_RS01850	COG1012	belongs to the aldehyde dehydrogenase family
CIT39_RS01855	COG1902	pentaerythritol trinitrate reductase activity
CIT39_RS01885	COG0765	amino acid transport
CIT39_RS01890	COG0765	amino acid transport
CIT39_RS01895	COG1126	abc transporter atp-binding protein
CIT39_RS01905	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CIT39_RS01920	COG0583	DNA-binding transcription factor activity
CIT39_RS01955	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CIT39_RS01965	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CIT39_RS01970	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CIT39_RS01990	COG1215	transferase activity, transferring glycosyl groups
CIT39_RS02010	COG0655	NAD(P)H dehydrogenase (quinone) activity
CIT39_RS02015	COG1741	Belongs to the pirin family
CIT39_RS02025	COG0583	DNA-binding transcription factor activity
CIT39_RS02030	COG1943	Transposase
CIT39_RS02050	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CIT39_RS02060	COG1733	regulation of RNA biosynthetic process
CIT39_RS02065	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS02075	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CIT39_RS02105	COG3474	cytochrome
CIT39_RS02110	COG0277	FAD linked oxidase domain protein
CIT39_RS02115	COG0277	FAD linked oxidase domain protein
CIT39_RS02120	COG0247	lactate metabolic process
CIT39_RS02135	COG4178	(ABC) transporter
CIT39_RS02140	COG1620	l-lactate permease
CIT39_RS02155	COG0459	protein refolding
CIT39_RS02160	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CIT39_RS02175	COG1388	LysM domain
CIT39_RS02175	COG1376	ErfK ybiS ycfS ynhG family protein
CIT39_RS02180	COG3416	Protein conserved in bacteria
CIT39_RS02190	COG0463	Glycosyl transferase, family 2
CIT39_RS02195	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CIT39_RS02200	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CIT39_RS02240	COG0312	modulator of DNA gyrase
CIT39_RS02260	COG1519	Transferase
CIT39_RS02265	COG1663	tetraacyldisaccharide 4'-kinase activity
CIT39_RS02285	COG1570	exodeoxyribonuclease VII activity
CIT39_RS02325	COG0151	Belongs to the GarS family
CIT39_RS02330	COG0596	Alpha beta hydrolase
CIT39_RS02335	COG0590	tRNA wobble adenosine to inosine editing
CIT39_RS02340	COG1187	pseudouridine synthase activity
CIT39_RS02345	COG0742	ribosomal rna small subunit methyltransferase
CIT39_RS02350	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CIT39_RS02385	COG0612	Peptidase, M16
CIT39_RS02390	COG0612	Peptidase, M16
CIT39_RS02400	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CIT39_RS02405	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CIT39_RS02410	COG0196	riboflavin kinase activity
CIT39_RS02415	COG0745	RESPONSE REGULATOR receiver
CIT39_RS02440	COG1295	ribonuclease BN
CIT39_RS02450	COG2890	protein-(glutamine-N5) methyltransferase activity
CIT39_RS02455	COG0314	molybdopterin synthase activity
CIT39_RS02465	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CIT39_RS02470	COG0322	excinuclease ABC activity
CIT39_RS02475	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CIT39_RS02480	COG1278	Cold shock
CIT39_RS02485	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CIT39_RS02515	COG0745	RESPONSE REGULATOR receiver
CIT39_RS02520	COG1846	Transcriptional regulator
CIT39_RS02535	COG0124	histidyl-tRNA synthetase
CIT39_RS02540	COG1942	4-Oxalocrotonate Tautomerase
CIT39_RS02555	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CIT39_RS02565	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CIT39_RS02570	COG1181	Belongs to the D-alanine--D-alanine ligase family
CIT39_RS02580	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CIT39_RS02590	COG1496	oxidoreductase activity
CIT39_RS02600	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CIT39_RS02615	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CIT39_RS02620	COG0193	aminoacyl-tRNA hydrolase activity
CIT39_RS02625	COG0012	GTP binding
CIT39_RS02635	COG2030	dehydratase
CIT39_RS02680	COG0556	nucleotide-excision repair
CIT39_RS02695	COG0583	DNA-binding transcription factor activity
CIT39_RS02735	COG0667	Aldo Keto reductase
CIT39_RS02755	COG0625	glutathione transferase activity
CIT39_RS02765	COG0436	Aminotransferase
CIT39_RS02775	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CIT39_RS02785	COG0659	secondary active sulfate transmembrane transporter activity
CIT39_RS02790	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CIT39_RS02810	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CIT39_RS02815	COG2223	nitrite transmembrane transporter activity
CIT39_RS02830	COG0625	glutathione transferase activity
CIT39_RS02850	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CIT39_RS02855	COG0183	Belongs to the thiolase family
CIT39_RS02860	COG0628	permease
CIT39_RS02865	COG2205	protein histidine kinase activity
CIT39_RS02880	COG0464	growth
CIT39_RS02885	COG1404	Belongs to the peptidase S8 family
CIT39_RS02890	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CIT39_RS02900	COG2301	Belongs to the HpcH HpaI aldolase family
CIT39_RS02920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CIT39_RS02925	COG0583	DNA-binding transcription factor activity
CIT39_RS02930	COG0492	ferredoxin-NADP+ reductase activity
CIT39_RS02935	COG1522	sequence-specific DNA binding
CIT39_RS02940	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CIT39_RS02945	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CIT39_RS02950	COG2814	Major facilitator Superfamily
CIT39_RS02980	COG0505	Belongs to the CarA family
CIT39_RS02995	COG0596	Alpha beta hydrolase
CIT39_RS03000	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CIT39_RS03055	COG0640	Transcriptional regulator
CIT39_RS03065	COG1280	lysine exporter protein (LysE YggA)
CIT39_RS03080	COG2105	PFAM AIG2 family protein
CIT39_RS03090	COG0358	DNA primase activity
CIT39_RS03095	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CIT39_RS03135	COG1280	lysine exporter protein (LysE YggA)
CIT39_RS03145	COG3706	GGDEF domain
CIT39_RS03160	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CIT39_RS03165	COG0564	pseudouridine synthase activity
CIT39_RS03230	COG0163	prenyltransferase activity
CIT39_RS03245	COG2814	Major facilitator Superfamily
CIT39_RS03265	COG0583	DNA-binding transcription factor activity
CIT39_RS03300	COG1132	(ABC) transporter
CIT39_RS03320	COG3064	Membrane
CIT39_RS03405	COG1136	(ABC) transporter
CIT39_RS03410	COG0210	DNA helicase
CIT39_RS03470	COG1176	ABC-type spermidine putrescine transport system, permease component I
CIT39_RS03475	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CIT39_RS03480	COG3842	ATPase activity
CIT39_RS03495	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CIT39_RS03500	COG3284	Transcriptional regulator
CIT39_RS03505	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CIT39_RS03515	COG3734	2-keto-3-deoxy-galactonokinase
CIT39_RS03520	COG0800	Aldolase
CIT39_RS03525	COG0028	Belongs to the TPP enzyme family
CIT39_RS03565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CIT39_RS03575	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CIT39_RS03590	COG1960	acyl-CoA dehydrogenase activity
CIT39_RS03595	COG1960	acyl-CoA dehydrogenase activity
CIT39_RS03600	COG1024	Enoyl-CoA hydratase
CIT39_RS03605	COG1704	LemA family
CIT39_RS03615	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CIT39_RS03635	COG0625	glutathione transferase activity
CIT39_RS03660	COG1278	Cold shock
CIT39_RS03685	COG3768	UPF0283 membrane protein
CIT39_RS03690	COG3106	COG3106 Predicted ATPase
CIT39_RS03695	COG1272	protein, Hemolysin III
CIT39_RS03700	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS03715	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS03735	COG1960	acyl-CoA dehydrogenase activity
CIT39_RS03740	COG0583	DNA-binding transcription factor activity
CIT39_RS03765	COG0501	Belongs to the peptidase M48B family
CIT39_RS03775	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CIT39_RS03790	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CIT39_RS03800	COG1376	ErfK ybiS ycfS ynhG family protein
CIT39_RS03805	COG0028	Belongs to the TPP enzyme family
CIT39_RS03835	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CIT39_RS03845	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS03880	COG0784	Response regulator, receiver
CIT39_RS03880	COG2198	Histidine kinase
CIT39_RS03880	COG0643	Histidine kinase
CIT39_RS03885	COG0835	chemotaxis
CIT39_RS03890	COG0643	Histidine kinase
CIT39_RS03890	COG0784	Response regulator, receiver
CIT39_RS03890	COG2198	Histidine kinase
CIT39_RS03895	COG2201	protein-glutamate methylesterase activity
CIT39_RS03905	COG0754	glutathionylspermidine amidase activity
CIT39_RS03935	COG3766	membrane
CIT39_RS03955	COG1595	DNA-templated transcription, initiation
CIT39_RS03990	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CIT39_RS04035	COG1309	transcriptional regulator
CIT39_RS04040	COG2080	2 iron, 2 sulfur cluster binding
CIT39_RS04045	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CIT39_RS04050	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CIT39_RS04060	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CIT39_RS04065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CIT39_RS04075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CIT39_RS04080	COG0765	amino acid transport
CIT39_RS04085	COG1126	abc transporter atp-binding protein
CIT39_RS04090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CIT39_RS04095	COG0405	Gamma-glutamyltransferase
CIT39_RS04100	COG1024	Enoyl-CoA hydratase
CIT39_RS04180	COG0411	ABC transporter
CIT39_RS04190	COG0683	leucine binding
CIT39_RS04195	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CIT39_RS04210	COG2226	methyltransferase
CIT39_RS04295	COG1129	ABC transporter
CIT39_RS04305	COG1172	Belongs to the binding-protein-dependent transport system permease family
CIT39_RS04310	COG1879	ABC-type sugar transport system periplasmic component
CIT39_RS04315	COG1172	Belongs to the binding-protein-dependent transport system permease family
CIT39_RS04330	COG1054	Belongs to the UPF0176 family
CIT39_RS04340	COG0366	Alpha amylase catalytic
CIT39_RS04345	COG0438	transferase activity, transferring glycosyl groups
CIT39_RS04380	COG3093	addiction module antidote protein HigA
CIT39_RS04420	COG0303	'Molybdopterin
CIT39_RS04430	COG0746	molybdenum cofactor guanylyltransferase activity
CIT39_RS04440	COG1763	Mo-molybdopterin cofactor biosynthetic process
CIT39_RS04460	COG5002	protein histidine kinase activity
CIT39_RS04465	COG2223	nitrite transmembrane transporter activity
CIT39_RS04480	COG3383	formate dehydrogenase (NAD+) activity
CIT39_RS04485	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CIT39_RS04505	COG2084	Dehydrogenase
CIT39_RS04510	COG1414	Transcriptional regulator
CIT39_RS04520	COG1053	succinate dehydrogenase
CIT39_RS04520	COG3976	FMN-binding domain protein
CIT39_RS04520	COG0431	NADPH-dependent FMN reductase
CIT39_RS04545	COG5001	Diguanylate cyclase
CIT39_RS04545	COG5002	protein histidine kinase activity
CIT39_RS04545	COG3447	MASE1 domain protein
CIT39_RS04550	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CIT39_RS04555	COG0583	DNA-binding transcription factor activity
CIT39_RS04560	COG3485	protocatechuate 3,4-dioxygenase
CIT39_RS04565	COG3485	protocatechuate 3,4-dioxygenase
CIT39_RS04600	COG0745	RESPONSE REGULATOR receiver
CIT39_RS04605	COG2198	Histidine kinase
CIT39_RS04605	COG0643	Histidine kinase
CIT39_RS04610	COG0835	chemotaxis
CIT39_RS04615	COG0840	transmembrane signaling receptor activity
CIT39_RS04625	COG0840	transmembrane signaling receptor activity
CIT39_RS04635	COG2201	protein-glutamate methylesterase activity
CIT39_RS04680	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CIT39_RS04690	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CIT39_RS04700	COG0489	protein tyrosine kinase activity
CIT39_RS04700	COG3206	protein involved in exopolysaccharide biosynthesis
CIT39_RS04740	COG2755	lipolytic protein G-D-S-L family
CIT39_RS04740	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CIT39_RS04750	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CIT39_RS04760	COG1215	transferase activity, transferring glycosyl groups
CIT39_RS04820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CIT39_RS04825	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CIT39_RS04940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CIT39_RS04975	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CIT39_RS05035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CIT39_RS05095	COG3206	protein involved in exopolysaccharide biosynthesis
CIT39_RS05095	COG0489	protein tyrosine kinase activity
CIT39_RS05165	COG0438	transferase activity, transferring glycosyl groups
CIT39_RS05185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CIT39_RS05230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CIT39_RS05235	COG5001	Diguanylate cyclase
CIT39_RS05235	COG3300	MHYT domain
CIT39_RS05265	COG0181	hydroxymethylbilane synthase activity
CIT39_RS05270	COG4566	intracellular signal transduction
CIT39_RS05275	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CIT39_RS05285	COG5001	Diguanylate cyclase
CIT39_RS05285	COG4251	negative regulation of phosphorylation
CIT39_RS05285	COG3706	GGDEF domain
CIT39_RS05285	COG2203	Gaf domain
CIT39_RS05290	COG2900	Belongs to the SlyX family
CIT39_RS05295	COG1054	Belongs to the UPF0176 family
CIT39_RS05300	COG0405	Gamma-glutamyltransferase
CIT39_RS05310	COG3237	CsbD-like
CIT39_RS05355	COG3214	Protein conserved in bacteria
CIT39_RS05380	COG1309	transcriptional regulator
CIT39_RS05405	COG1607	acyl-coa hydrolase
CIT39_RS05425	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CIT39_RS05430	COG1349	DNA-binding transcription factor activity
CIT39_RS05450	COG3842	ATPase activity
CIT39_RS05455	COG3842	ATPase activity
CIT39_RS05465	COG0395	ABC-type sugar transport system, permease component
CIT39_RS05480	COG1902	pentaerythritol trinitrate reductase activity
CIT39_RS05505	COG0501	Belongs to the peptidase M48B family
CIT39_RS05555	COG0494	nUDIX hydrolase
CIT39_RS05575	COG4771	TonB-dependent receptor
CIT39_RS05600	COG0714	Associated with various cellular activities
CIT39_RS05620	COG0617	tRNA 3'-terminal CCA addition
CIT39_RS05635	COG2943	transferase activity, transferring hexosyl groups
CIT39_RS05640	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CIT39_RS05660	COG0408	coproporphyrinogen oxidase activity
CIT39_RS05665	COG0602	queuosine metabolic process
CIT39_RS05670	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CIT39_RS05675	COG0723	plastoquinol--plastocyanin reductase activity
CIT39_RS05680	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CIT39_RS05680	COG2857	Cytochrome c1
CIT39_RS05705	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CIT39_RS05730	COG1704	LemA family
CIT39_RS05740	COG1196	nuclear chromosome segregation
CIT39_RS05745	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CIT39_RS05755	COG1194	a g-specific adenine glycosylase
CIT39_RS05760	COG3706	GGDEF domain
CIT39_RS05775	COG0625	glutathione transferase activity
CIT39_RS05800	COG4251	negative regulation of phosphorylation
CIT39_RS05805	COG0840	transmembrane signaling receptor activity
CIT39_RS05810	COG0625	glutathione transferase activity
CIT39_RS05815	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CIT39_RS05820	COG2321	neutral zinc metallopeptidase
CIT39_RS05825	COG0521	Mo-molybdopterin cofactor biosynthetic process
CIT39_RS05830	COG0456	acetyltransferase
CIT39_RS05830	COG1846	Transcriptional regulator
CIT39_RS05845	COG0574	Belongs to the PEP-utilizing enzyme family
CIT39_RS05845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CIT39_RS05860	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CIT39_RS05875	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CIT39_RS05885	COG1573	uracil-dna glycosylase
CIT39_RS05900	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CIT39_RS05910	COG1280	lysine exporter protein (LysE YggA)
CIT39_RS05915	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CIT39_RS05925	COG0142	geranyltranstransferase activity
CIT39_RS05935	COG2813	Specifically methylates the guanine in position
CIT39_RS05955	COG0752	glycyl-tRNA synthetase alpha subunit
CIT39_RS05960	COG0751	glycine-tRNA ligase activity
CIT39_RS05975	COG0574	Belongs to the PEP-utilizing enzyme family
CIT39_RS05975	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CIT39_RS05980	COG3409	Peptidoglycan-binding domain 1 protein
CIT39_RS05980	COG3773	Cell wall hydrolase
CIT39_RS05990	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CIT39_RS05995	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CIT39_RS06005	COG0604	alcohol dehydrogenase
CIT39_RS06050	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CIT39_RS06055	COG0519	Catalyzes the synthesis of GMP from XMP
CIT39_RS06060	COG0354	folic acid binding
CIT39_RS06065	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CIT39_RS06070	COG2897	thiosulfate sulfurtransferase activity
CIT39_RS06095	COG2135	peptidase activity
CIT39_RS06110	COG0494	nUDIX hydrolase
CIT39_RS06120	COG0277	FAD linked oxidase domain protein
CIT39_RS06125	COG0009	L-threonylcarbamoyladenylate synthase
CIT39_RS06165	COG1476	TRANSCRIPTIONal
CIT39_RS06255	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
CIT39_RS06265	COG4245	von Willebrand factor, type A
CIT39_RS06350	COG2188	Transcriptional regulator
CIT39_RS06360	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CIT39_RS06370	COG2188	Transcriptional regulator
CIT39_RS06375	COG3842	ATPase activity
CIT39_RS06380	COG0395	ABC-type sugar transport system, permease component
CIT39_RS06385	COG1175	transmembrane transport
CIT39_RS06415	COG0604	alcohol dehydrogenase
CIT39_RS06415	COG4221	oxidoreductase activity
CIT39_RS06415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CIT39_RS06415	COG3321	synthase
CIT39_RS06440	COG2814	Major facilitator Superfamily
CIT39_RS06445	COG0134	indole-3-glycerol-phosphate synthase activity
CIT39_RS06470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CIT39_RS06495	COG2140	Oxalate decarboxylase
CIT39_RS06505	COG4566	intracellular signal transduction
CIT39_RS06510	COG4566	intracellular signal transduction
CIT39_RS06535	COG2205	protein histidine kinase activity
CIT39_RS06535	COG0784	Response regulator, receiver
CIT39_RS06535	COG5002	protein histidine kinase activity
CIT39_RS06580	COG2864	formate dehydrogenase
CIT39_RS06585	COG0437	4 iron, 4 sulfur cluster binding
CIT39_RS06590	COG3383	formate dehydrogenase (NAD+) activity
CIT39_RS06590	COG0243	molybdopterin cofactor binding
CIT39_RS06600	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CIT39_RS06625	COG1309	transcriptional regulator
CIT39_RS06630	COG2814	Major facilitator Superfamily
CIT39_RS06655	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CIT39_RS06675	COG1850	ribulose-bisphosphate carboxylase activity
CIT39_RS06680	COG4451	ribulose bisphosphate carboxylase, small
CIT39_RS06710	COG0589	response to stress
CIT39_RS06745	COG0693	protein deglycase activity
CIT39_RS06810	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS06860	COG0656	L-ascorbic acid biosynthetic process
CIT39_RS06880	COG3384	dioxygenase
CIT39_RS06885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CIT39_RS06895	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CIT39_RS06895	COG0475	glutathione-regulated potassium exporter activity
CIT39_RS06905	COG1960	acyl-CoA dehydrogenase activity
CIT39_RS06920	COG0318	PFAM AMP-dependent synthetase and ligase
CIT39_RS06935	COG0598	Magnesium transport protein CorA
CIT39_RS06950	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS06955	COG0259	pyridoxamine-phosphate oxidase activity
CIT39_RS06980	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CIT39_RS06990	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CIT39_RS07005	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CIT39_RS07010	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CIT39_RS07040	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CIT39_RS07045	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CIT39_RS07055	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CIT39_RS07060	COG1722	exodeoxyribonuclease VII activity
CIT39_RS07065	COG0123	including yeast histone deacetylase and acetoin utilization protein
CIT39_RS07070	COG1525	nuclease
CIT39_RS07070	COG4085	toxin activity
CIT39_RS07070	COG0737	Belongs to the 5'-nucleotidase family
CIT39_RS07085	COG1960	acyl-CoA dehydrogenase activity
CIT39_RS07100	COG0071	Belongs to the small heat shock protein (HSP20) family
CIT39_RS07120	COG0346	lactoylglutathione lyase activity
CIT39_RS07125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CIT39_RS07145	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CIT39_RS07155	COG1473	amidohydrolase
CIT39_RS07160	COG4948	Mandelate Racemase Muconate Lactonizing
CIT39_RS07190	COG0741	lytic transglycosylase activity
CIT39_RS07225	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CIT39_RS07235	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CIT39_RS07255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CIT39_RS07275	COG1335	isochorismatase
CIT39_RS07285	COG3258	Cytochrome c
CIT39_RS07305	COG0446	pyridine nucleotide-disulphide oxidoreductase
CIT39_RS07310	COG2010	Cytochrome c
CIT39_RS07310	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CIT39_RS07320	COG1032	radical SAM domain protein
CIT39_RS07330	COG2814	Major facilitator Superfamily
CIT39_RS07335	COG0473	3-isopropylmalate dehydrogenase activity
CIT39_RS07385	COG4106	trans-aconitate 2-methyltransferase activity
CIT39_RS07400	COG3706	GGDEF domain
CIT39_RS07405	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CIT39_RS07410	COG0438	transferase activity, transferring glycosyl groups
CIT39_RS07415	COG1132	(ABC) transporter
CIT39_RS07435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CIT39_RS07445	COG4566	intracellular signal transduction
CIT39_RS07450	COG4191	Histidine kinase
CIT39_RS07460	COG0517	IMP dehydrogenase activity
CIT39_RS07460	COG0516	GMP reductase activity
CIT39_RS07465	COG3278	Belongs to the heme-copper respiratory oxidase family
CIT39_RS07480	COG2010	Cytochrome c
CIT39_RS07495	COG2217	Heavy metal translocating P-type atpase
CIT39_RS07525	COG0583	DNA-binding transcription factor activity
CIT39_RS07530	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS07540	COG0297	glycogen (starch) synthase activity
CIT39_RS07545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CIT39_RS07550	COG0747	negative chemotaxis
CIT39_RS07560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CIT39_RS07565	COG0444	Belongs to the ABC transporter superfamily
CIT39_RS07580	COG0473	3-isopropylmalate dehydrogenase activity
CIT39_RS07590	COG1024	Enoyl-CoA hydratase
CIT39_RS07595	COG1396	sequence-specific DNA binding
CIT39_RS07615	COG0785	Cytochrome C biogenesis protein
CIT39_RS07630	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CIT39_RS07630	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CIT39_RS07635	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CIT39_RS07635	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CIT39_RS07645	COG3485	protocatechuate 3,4-dioxygenase
CIT39_RS07650	COG0583	DNA-binding transcription factor activity
CIT39_RS07655	COG0702	epimerase
CIT39_RS07660	COG2815	serine threonine protein kinase
CIT39_RS07660	COG0515	serine threonine protein kinase
CIT39_RS07675	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CIT39_RS07680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CIT39_RS07685	COG1116	anion transmembrane transporter activity
CIT39_RS07690	COG2223	nitrite transmembrane transporter activity
CIT39_RS07700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CIT39_RS07705	COG0243	molybdopterin cofactor binding
CIT39_RS07715	COG0656	L-ascorbic acid biosynthetic process
CIT39_RS07720	COG0697	spore germination
CIT39_RS07725	COG1063	alcohol dehydrogenase
CIT39_RS07730	COG1522	sequence-specific DNA binding
CIT39_RS07735	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CIT39_RS07750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CIT39_RS07755	COG2020	methyltransferase activity
CIT39_RS07770	COG3710	Transcriptional regulator
CIT39_RS07770	COG0457	Tetratricopeptide repeat
CIT39_RS07785	COG0129	dihydroxy-acid dehydratase activity
CIT39_RS07800	COG1024	Enoyl-CoA hydratase
CIT39_RS07810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CIT39_RS07815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CIT39_RS07825	COG1309	transcriptional regulator
CIT39_RS07830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CIT39_RS07850	COG0673	inositol 2-dehydrogenase activity
CIT39_RS07865	COG2124	cytochrome p450
CIT39_RS07875	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
CIT39_RS07875	COG0028	Belongs to the TPP enzyme family
CIT39_RS07885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CIT39_RS07890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CIT39_RS07900	COG2204	response regulator
CIT39_RS07905	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CIT39_RS07915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CIT39_RS07920	COG0601	transmembrane transport
CIT39_RS07925	COG0747	negative chemotaxis
CIT39_RS07930	COG4608	Belongs to the ABC transporter superfamily
CIT39_RS07935	COG0444	Belongs to the ABC transporter superfamily
CIT39_RS07950	COG4608	Belongs to the ABC transporter superfamily
CIT39_RS07955	COG0444	Belongs to the ABC transporter superfamily
CIT39_RS07960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CIT39_RS07965	COG0601	transmembrane transport
CIT39_RS07970	COG0747	negative chemotaxis
CIT39_RS07990	COG2267	carboxylic ester hydrolase activity
CIT39_RS07995	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CIT39_RS07995	COG2124	cytochrome p450
CIT39_RS08005	COG0596	Alpha beta hydrolase
CIT39_RS08030	COG2733	membrane
CIT39_RS08035	COG0596	Alpha beta hydrolase
CIT39_RS08040	COG3327	negative regulation of DNA-templated transcription, initiation
CIT39_RS08045	COG3396	Phenylacetate-CoA oxygenase
CIT39_RS08050	COG3460	Phenylacetate-CoA oxygenase
CIT39_RS08055	COG3396	Phenylacetate-CoA oxygenase
CIT39_RS08060	COG2151	metal-sulfur cluster biosynthetic enzyme
CIT39_RS08065	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CIT39_RS08070	COG2050	protein possibly involved in aromatic compounds catabolism
CIT39_RS08095	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CIT39_RS08100	COG0477	Major facilitator Superfamily
CIT39_RS08125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CIT39_RS08130	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CIT39_RS08140	COG4597	amino acid ABC transporter
CIT39_RS08145	COG0765	amino acid transport
CIT39_RS08155	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS08160	COG0473	3-isopropylmalate dehydrogenase activity
CIT39_RS08165	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CIT39_RS08170	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIT39_RS08180	COG0583	DNA-binding transcription factor activity
CIT39_RS08185	COG4336	lyase activity
CIT39_RS08195	COG0559	Belongs to the binding-protein-dependent transport system permease family
CIT39_RS08205	COG1137	ATPase activity
CIT39_RS08215	COG0235	Class ii aldolase
CIT39_RS08220	COG2084	Dehydrogenase
CIT39_RS08225	COG3622	Belongs to the hyi family
CIT39_RS08230	COG3395	kinase activity
CIT39_RS08235	COG0840	transmembrane signaling receptor activity
CIT39_RS08240	COG0840	transmembrane signaling receptor activity
CIT39_RS08245	COG0840	transmembrane signaling receptor activity
CIT39_RS08255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CIT39_RS08270	COG2070	2-Nitropropane dioxygenase
CIT39_RS08275	COG0625	glutathione transferase activity
CIT39_RS08285	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CIT39_RS08300	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS08305	COG1024	Enoyl-CoA hydratase
CIT39_RS08320	COG1024	Enoyl-CoA hydratase
CIT39_RS08325	COG1960	acyl-CoA dehydrogenase activity
CIT39_RS08340	COG1024	Enoyl-CoA hydratase
CIT39_RS08350	COG1024	Enoyl-CoA hydratase
CIT39_RS08375	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CIT39_RS08380	COG3386	PFAM SMP-30 Gluconolaconase
CIT39_RS08385	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS08415	COG3145	DNA-N1-methyladenine dioxygenase activity
CIT39_RS08425	COG0028	Belongs to the TPP enzyme family
CIT39_RS08430	COG0179	Fumarylacetoacetate (FAA) hydrolase
CIT39_RS08440	COG1012	belongs to the aldehyde dehydrogenase family
CIT39_RS08450	COG3971	2-oxopent-4-enoate hydratase activity
CIT39_RS08455	COG1846	Transcriptional regulator
CIT39_RS08460	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CIT39_RS08470	COG2721	sulfolactate sulfo-lyase activity
CIT39_RS08500	COG1335	isochorismatase
CIT39_RS08510	COG0583	DNA-binding transcription factor activity
CIT39_RS08525	COG0395	ABC-type sugar transport system, permease component
CIT39_RS08530	COG1175	transmembrane transport
CIT39_RS08535	COG3842	ATPase activity
CIT39_RS08580	COG2267	carboxylic ester hydrolase activity
CIT39_RS08590	COG4303	Ethanolamine ammonia lyase large subunit
CIT39_RS08600	COG4302	ethanolamine ammonia-lyase activity
CIT39_RS08625	COG1562	ergosterol biosynthetic process
CIT39_RS08630	COG1562	ergosterol biosynthetic process
CIT39_RS08635	COG1233	COG1233 Phytoene dehydrogenase and related
CIT39_RS08640	COG1657	PFAM Prenyltransferase squalene oxidase
CIT39_RS08665	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CIT39_RS08695	COG1595	DNA-templated transcription, initiation
CIT39_RS08720	COG1473	amidohydrolase
CIT39_RS08725	COG0306	phosphate transporter
CIT39_RS08730	COG1573	uracil-dna glycosylase
CIT39_RS08750	COG0587	DNA-directed DNA polymerase activity
CIT39_RS08755	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS08765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CIT39_RS08790	COG1024	Enoyl-CoA hydratase
CIT39_RS08860	COG1703	isobutyryl-CoA mutase activity
CIT39_RS08905	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CIT39_RS08915	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CIT39_RS08930	COG0433	COG0433 Predicted ATPase
CIT39_RS08960	COG4957	zinc ion binding
CIT39_RS08965	COG2166	iron-sulfur cluster assembly
CIT39_RS08975	COG2205	protein histidine kinase activity
CIT39_RS09035	COG0798	PFAM Bile acid sodium symporter
CIT39_RS09115	COG2983	Belongs to the UPF0260 family
CIT39_RS09120	COG2814	Major facilitator Superfamily
CIT39_RS09130	COG0028	Belongs to the TPP enzyme family
CIT39_RS09145	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CIT39_RS09150	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CIT39_RS09155	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CIT39_RS09170	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CIT39_RS09195	COG4235	cytochrome complex assembly
CIT39_RS09200	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CIT39_RS09205	COG1138	Cytochrome C-type biogenesis protein
CIT39_RS09210	COG3088	subunit of a heme lyase
CIT39_RS09225	COG0745	RESPONSE REGULATOR receiver
CIT39_RS09230	COG2205	protein histidine kinase activity
CIT39_RS09235	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CIT39_RS09245	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CIT39_RS09250	COG3383	formate dehydrogenase (NAD+) activity
CIT39_RS09265	COG0583	DNA-binding transcription factor activity
CIT39_RS09270	COG2205	protein histidine kinase activity
CIT39_RS09270	COG2202	Pas domain
CIT39_RS09275	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CIT39_RS09280	COG3321	synthase
CIT39_RS09280	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS09280	COG0604	alcohol dehydrogenase
CIT39_RS09320	COG0179	Fumarylacetoacetate (FAA) hydrolase
CIT39_RS09325	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CIT39_RS09365	COG0443	Heat shock 70 kDa protein
CIT39_RS09385	COG1278	Cold shock
CIT39_RS09405	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CIT39_RS09415	COG1802	Transcriptional regulator
CIT39_RS09425	COG1414	Transcriptional regulator
CIT39_RS09450	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CIT39_RS09455	COG3960	tartronate-semialdehyde synthase activity
CIT39_RS09460	COG3622	Belongs to the hyi family
CIT39_RS09465	COG2084	Dehydrogenase
CIT39_RS09490	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIT39_RS09500	COG1247	-acetyltransferase
CIT39_RS09505	COG1982	Orn Lys Arg decarboxylase major
CIT39_RS09510	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CIT39_RS09515	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CIT39_RS09520	COG2080	2 iron, 2 sulfur cluster binding
CIT39_RS09530	COG2072	flavoprotein involved in K transport
CIT39_RS09535	COG1309	transcriptional regulator
CIT39_RS09540	COG0318	PFAM AMP-dependent synthetase and ligase
CIT39_RS09565	COG0410	ABC transporter
CIT39_RS09575	COG2855	membrane
CIT39_RS09585	COG1879	ABC-type sugar transport system periplasmic component
CIT39_RS09590	COG1129	ABC transporter
CIT39_RS09595	COG1172	Belongs to the binding-protein-dependent transport system permease family
CIT39_RS09600	COG1172	Belongs to the binding-protein-dependent transport system permease family
CIT39_RS09620	COG3386	PFAM SMP-30 Gluconolaconase
CIT39_RS09625	COG4213	ABC transporter substrate-binding protein
CIT39_RS09635	COG4214	carbohydrate transport
CIT39_RS09640	COG1845	cytochrome c oxidase, subunit III
CIT39_RS09655	COG3256	nitric oxide reductase
CIT39_RS09660	COG0714	Associated with various cellular activities
CIT39_RS09680	COG0154	amidase activity
CIT39_RS09690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CIT39_RS09695	COG0444	Belongs to the ABC transporter superfamily
CIT39_RS09700	COG4608	Belongs to the ABC transporter superfamily
CIT39_RS09705	COG0747	negative chemotaxis
CIT39_RS09715	COG0400	carboxylic ester hydrolase activity
CIT39_RS09720	COG0346	lactoylglutathione lyase activity
CIT39_RS09725	COG0583	DNA-binding transcription factor activity
CIT39_RS09735	COG0778	Nitroreductase
CIT39_RS09740	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CIT39_RS09750	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CIT39_RS09760	COG1492	cobalamin metabolic process
CIT39_RS09805	COG2099	Precorrin-6x reductase
CIT39_RS09820	COG2875	Belongs to the precorrin methyltransferase family
CIT39_RS09825	COG1797	cobyrinic acid a,c-diamide synthase activity
CIT39_RS09830	COG1648	precorrin-2 dehydrogenase activity
CIT39_RS09830	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CIT39_RS09845	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CIT39_RS09880	COG2207	Transcriptional regulator
CIT39_RS09895	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CIT39_RS09905	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CIT39_RS09925	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS09930	COG2072	flavoprotein involved in K transport
CIT39_RS09935	COG0747	negative chemotaxis
CIT39_RS09940	COG0601	transmembrane transport
CIT39_RS09945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CIT39_RS09955	COG0747	negative chemotaxis
CIT39_RS09960	COG0601	transmembrane transport
CIT39_RS09965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CIT39_RS09970	COG0444	Belongs to the ABC transporter superfamily
CIT39_RS09975	COG4608	Belongs to the ABC transporter superfamily
CIT39_RS09985	COG1879	ABC-type sugar transport system periplasmic component
CIT39_RS09990	COG1172	Belongs to the binding-protein-dependent transport system permease family
CIT39_RS09995	COG1172	Belongs to the binding-protein-dependent transport system permease family
CIT39_RS10000	COG1129	ABC transporter
CIT39_RS10005	COG0277	FAD linked oxidase domain protein
CIT39_RS10010	COG3485	protocatechuate 3,4-dioxygenase
CIT39_RS10015	COG2084	Dehydrogenase
CIT39_RS10020	COG0402	S-adenosylhomocysteine deaminase activity
CIT39_RS10025	COG1454	alcohol dehydrogenase
CIT39_RS10055	COG0445	tRNA wobble uridine modification
CIT39_RS10085	COG0559	Belongs to the binding-protein-dependent transport system permease family
CIT39_RS10110	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS10125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CIT39_RS10130	COG4566	intracellular signal transduction
CIT39_RS10135	COG4566	intracellular signal transduction
CIT39_RS10150	COG2985	domain, Protein
CIT39_RS10200	COG4191	Histidine kinase
CIT39_RS10205	COG3064	Membrane
CIT39_RS10225	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CIT39_RS10245	COG0640	Transcriptional regulator
CIT39_RS10255	COG0785	Cytochrome C biogenesis protein
CIT39_RS10290	COG0737	Belongs to the 5'-nucleotidase family
CIT39_RS10295	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CIT39_RS10320	COG2391	methyltransferase activity
CIT39_RS10325	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS10335	COG1653	transport
CIT39_RS10350	COG1063	alcohol dehydrogenase
CIT39_RS10355	COG3842	ATPase activity
CIT39_RS10360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CIT39_RS10365	COG3684	Belongs to the aldolase LacD family
CIT39_RS10375	COG1116	anion transmembrane transporter activity
CIT39_RS10380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CIT39_RS10385	COG4521	taurine ABC transporter
CIT39_RS10390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CIT39_RS10405	COG1053	succinate dehydrogenase
CIT39_RS10430	COG0573	inorganic phosphate transmembrane transporter activity
CIT39_RS10435	COG3842	ATPase activity
CIT39_RS10460	COG0583	DNA-binding transcription factor activity
CIT39_RS10465	COG0154	amidase activity
CIT39_RS10475	COG2351	hydroxyisourate hydrolase activity
CIT39_RS10485	COG1176	ABC-type spermidine putrescine transport system, permease component I
CIT39_RS10490	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CIT39_RS10495	COG3842	ATPase activity
CIT39_RS10510	COG1802	Transcriptional regulator
CIT39_RS10520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CIT39_RS10525	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CIT39_RS10555	COG2205	protein histidine kinase activity
CIT39_RS10560	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CIT39_RS10565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CIT39_RS10570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CIT39_RS10595	COG3038	cytochrome b561
CIT39_RS10610	COG2140	Oxalate decarboxylase
CIT39_RS10615	COG0243	molybdopterin cofactor binding
CIT39_RS10620	COG4191	Histidine kinase
CIT39_RS10630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CIT39_RS10660	COG3052	prosthetic group binding
CIT39_RS10680	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CIT39_RS10705	COG4566	intracellular signal transduction
CIT39_RS10710	COG4191	Histidine kinase
CIT39_RS10735	COG2205	protein histidine kinase activity
CIT39_RS10735	COG2202	Pas domain
CIT39_RS10740	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CIT39_RS10745	COG2084	Dehydrogenase
CIT39_RS10760	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CIT39_RS10765	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CIT39_RS10780	COG0745	RESPONSE REGULATOR receiver
CIT39_RS10785	COG5002	protein histidine kinase activity
CIT39_RS10790	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CIT39_RS10800	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CIT39_RS10810	COG0546	phosphoglycolate phosphatase activity
CIT39_RS10815	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CIT39_RS10855	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CIT39_RS10860	COG0121	glutamine amidotransferase
CIT39_RS10875	COG1017	nitric oxide dioxygenase activity
CIT39_RS10875	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CIT39_RS10895	COG0861	Integral membrane protein TerC family
CIT39_RS10915	COG2267	carboxylic ester hydrolase activity
CIT39_RS10920	COG0431	NADPH-dependent FMN reductase
CIT39_RS10930	COG2197	response regulator
CIT39_RS10955	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CIT39_RS10960	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CIT39_RS10980	COG0215	cysteine-tRNA ligase activity
CIT39_RS10990	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CIT39_RS11005	COG5265	(ABC) transporter
CIT39_RS11010	COG0688	phosphatidylethanolamine metabolic process
CIT39_RS11015	COG1183	phosphatidylcholine synthase activity
CIT39_RS11030	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CIT39_RS11040	COG3158	transport of potassium into the cell
CIT39_RS11045	COG3158	transport of potassium into the cell
CIT39_RS11055	COG0436	Aminotransferase
CIT39_RS11060	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CIT39_RS11070	COG3710	Transcriptional regulator
CIT39_RS11070	COG0457	Tetratricopeptide repeat
CIT39_RS11075	COG1560	Kdo2-lipid A biosynthetic process
CIT39_RS11080	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CIT39_RS11090	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CIT39_RS11095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CIT39_RS11120	COG1285	pathogenesis
CIT39_RS11140	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CIT39_RS11140	COG2010	Cytochrome c
CIT39_RS11145	COG2080	2 iron, 2 sulfur cluster binding
CIT39_RS11185	COG1846	Transcriptional regulator
CIT39_RS11250	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CIT39_RS11295	COG0318	PFAM AMP-dependent synthetase and ligase
CIT39_RS11300	COG2072	flavoprotein involved in K transport
CIT39_RS11380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CIT39_RS11385	COG1309	transcriptional regulator
CIT39_RS11400	COG2814	Major facilitator Superfamily
CIT39_RS11405	COG1012	belongs to the aldehyde dehydrogenase family
CIT39_RS11410	COG1802	Transcriptional regulator
CIT39_RS11420	COG0477	Major facilitator Superfamily
CIT39_RS11425	COG0402	S-adenosylhomocysteine deaminase activity
CIT39_RS11435	COG0789	Transcriptional regulator
CIT39_RS11445	COG1234	tRNA 3'-trailer cleavage
CIT39_RS11465	COG5507	3-demethylubiquinone-9 3-methyltransferase
CIT39_RS11485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CIT39_RS11490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CIT39_RS11500	COG4774	siderophore transport
CIT39_RS11505	COG3128	pkhd-type hydroxylase
CIT39_RS11515	COG0848	biopolymer transport protein
CIT39_RS11530	COG1994	Peptidase M50
CIT39_RS11545	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS11555	COG0129	dihydroxy-acid dehydratase activity
CIT39_RS11560	COG1609	Transcriptional regulator
CIT39_RS11565	COG3842	ATPase activity
CIT39_RS11580	COG0395	ABC-type sugar transport system, permease component
CIT39_RS11585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CIT39_RS11590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CIT39_RS11595	COG0800	Aldolase
CIT39_RS11600	COG0183	Belongs to the thiolase family
CIT39_RS11610	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CIT39_RS11615	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CIT39_RS11635	COG2066	Belongs to the glutaminase family
CIT39_RS11635	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CIT39_RS11660	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CIT39_RS11675	COG0277	FAD linked oxidase domain protein
CIT39_RS11700	COG2271	Major facilitator Superfamily
CIT39_RS11705	COG0183	Belongs to the thiolase family
CIT39_RS11710	COG1024	Enoyl-CoA hydratase
CIT39_RS11735	COG1960	acyl-CoA dehydrogenase activity
CIT39_RS11760	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS11765	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CIT39_RS11765	COG0493	'glutamate synthase
CIT39_RS11775	COG0488	(ABC) transporter
CIT39_RS11780	COG1671	Belongs to the UPF0178 family
CIT39_RS11800	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CIT39_RS11815	COG2130	NADP-dependent
CIT39_RS11845	COG1278	Cold shock
CIT39_RS11855	COG2814	Major facilitator Superfamily
CIT39_RS11870	COG0519	Catalyzes the synthesis of GMP from XMP
CIT39_RS11870	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CIT39_RS11905	COG0640	Transcriptional regulator
CIT39_RS11915	COG0701	Predicted permease
CIT39_RS11920	COG0242	peptide deformylase activity
CIT39_RS11925	COG0583	DNA-binding transcription factor activity
CIT39_RS11935	COG1063	alcohol dehydrogenase
CIT39_RS12005	COG0625	glutathione transferase activity
CIT39_RS12015	COG1309	transcriptional regulator
CIT39_RS12020	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CIT39_RS12020	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CIT39_RS12025	COG1393	Belongs to the ArsC family
CIT39_RS12050	COG0559	Belongs to the binding-protein-dependent transport system permease family
CIT39_RS12060	COG1392	Phosphate transport regulator
CIT39_RS12065	COG0306	phosphate transporter
CIT39_RS12090	COG0318	PFAM AMP-dependent synthetase and ligase
CIT39_RS12105	COG1160	GTP binding
CIT39_RS12125	COG0300	oxidoreductase activity
CIT39_RS12130	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CIT39_RS12135	COG1286	toxin biosynthetic process
CIT39_RS12145	COG1879	ABC-type sugar transport system periplasmic component
CIT39_RS12170	COG0297	glycogen (starch) synthase activity
CIT39_RS12175	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CIT39_RS12185	COG0708	Exodeoxyribonuclease III
CIT39_RS12195	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CIT39_RS12200	COG0305	Participates in initiation and elongation during chromosome replication
CIT39_RS12210	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CIT39_RS12230	COG0359	binds to the 23S rRNA
CIT39_RS12240	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CIT39_RS12245	COG0360	Binds together with S18 to 16S ribosomal RNA
CIT39_RS12260	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CIT39_RS12270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CIT39_RS12275	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CIT39_RS12280	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CIT39_RS12285	COG1561	YicC-like family, N-terminal region
CIT39_RS12290	COG0194	GDP metabolic process
CIT39_RS12315	COG3964	amidohydrolase
CIT39_RS12345	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
CIT39_RS12375	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CIT39_RS12380	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CIT39_RS12390	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CIT39_RS12405	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CIT39_RS12420	COG0488	(ABC) transporter
CIT39_RS12430	COG0105	UTP biosynthetic process
CIT39_RS12435	COG0861	Integral membrane protein TerC family
CIT39_RS12480	COG0248	Ppx GppA phosphatase
CIT39_RS12495	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CIT39_RS12500	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CIT39_RS12505	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CIT39_RS12515	COG1278	Cold shock
CIT39_RS12540	COG2153	protein acetylation
CIT39_RS12555	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CIT39_RS12560	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CIT39_RS12575	COG1175	transmembrane transport
CIT39_RS12585	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CIT39_RS12590	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CIT39_RS12600	COG0280	phosphate acetyltransferase
CIT39_RS12600	COG0281	malic enzyme
CIT39_RS12620	COG0386	Belongs to the glutathione peroxidase family
CIT39_RS12630	COG3045	CreA protein
CIT39_RS12660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CIT39_RS12670	COG3483	tryptophan 2,3-dioxygenase activity
CIT39_RS12705	COG2365	Tyrosine phosphatase family
CIT39_RS12725	COG0174	glutamine synthetase
CIT39_RS12760	COG1278	Cold shock
CIT39_RS12780	COG0488	(ABC) transporter
CIT39_RS12805	COG0657	acetylesterase activity
CIT39_RS12810	COG0778	Nitroreductase
CIT39_RS12835	COG2207	Transcriptional regulator
CIT39_RS12855	COG0840	transmembrane signaling receptor activity
CIT39_RS12875	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CIT39_RS12900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CIT39_RS12905	COG1309	transcriptional regulator
CIT39_RS12915	COG0850	regulation of cytokinetic process
CIT39_RS12920	COG2894	cell division
CIT39_RS12925	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CIT39_RS12945	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS12960	COG1376	ErfK ybiS ycfS ynhG family protein
CIT39_RS13020	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CIT39_RS13045	COG2824	Alkylphosphonate utilization operon protein PhnA
CIT39_RS13085	COG4106	trans-aconitate 2-methyltransferase activity
CIT39_RS13115	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CIT39_RS13120	COG0697	spore germination
CIT39_RS13150	COG4191	Histidine kinase
CIT39_RS13150	COG0784	Response regulator, receiver
CIT39_RS13200	COG0657	acetylesterase activity
CIT39_RS13210	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CIT39_RS13215	COG3920	Histidine kinase
CIT39_RS13220	COG0784	Response regulator, receiver
CIT39_RS13225	COG5002	protein histidine kinase activity
CIT39_RS13230	COG0439	Biotin carboxylase
CIT39_RS13235	COG0511	ligase activity, forming carbon-carbon bonds
CIT39_RS13240	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CIT39_RS13260	COG0436	Aminotransferase
CIT39_RS13265	COG1268	BioY protein
CIT39_RS13270	COG1301	dicarboxylic acid transport
CIT39_RS13285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CIT39_RS13290	COG1530	ribonuclease E activity
CIT39_RS13290	COG1530	ribonuclease E activity
CIT39_RS13300	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CIT39_RS13310	COG2084	Dehydrogenase
CIT39_RS13325	COG1473	amidohydrolase
CIT39_RS13330	COG0697	spore germination
CIT39_RS13340	COG0739	heme binding
CIT39_RS13360	COG2259	Doxx family
CIT39_RS13365	COG2271	Major facilitator Superfamily
CIT39_RS13370	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CIT39_RS13375	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CIT39_RS13390	COG2945	thiolester hydrolase activity
CIT39_RS13395	COG1104	cysteine desulfurase activity
CIT39_RS13400	COG0719	Fe-S assembly protein
CIT39_RS13405	COG0396	ATPase activity
CIT39_RS13410	COG0719	Fe-S assembly protein
CIT39_RS13415	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CIT39_RS13425	COG0316	Belongs to the HesB IscA family
CIT39_RS13435	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CIT39_RS13445	COG0513	Belongs to the DEAD box helicase family
CIT39_RS13475	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS13490	COG0187	DNA topoisomerase II activity
CIT39_RS13495	COG0586	Pfam SNARE associated Golgi protein
CIT39_RS13510	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CIT39_RS13525	COG3243	poly(R)-hydroxyalkanoic acid synthase
CIT39_RS13535	COG0436	Aminotransferase
CIT39_RS13545	COG1494	fructose-1,6-bisphosphatase
CIT39_RS13570	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CIT39_RS13575	COG1802	Transcriptional regulator
CIT39_RS13580	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CIT39_RS13585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CIT39_RS13605	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CIT39_RS13620	COG0840	transmembrane signaling receptor activity
CIT39_RS13625	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CIT39_RS13665	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CIT39_RS13675	COG2354	Protein conserved in bacteria
CIT39_RS13685	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CIT39_RS13705	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CIT39_RS13785	COG3077	Addiction module antitoxin, RelB DinJ family
CIT39_RS13805	COG0776	regulation of translation
CIT39_RS13830	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CIT39_RS13880	COG1522	sequence-specific DNA binding
CIT39_RS13895	COG1960	acyl-CoA dehydrogenase activity
CIT39_RS13900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CIT39_RS13905	COG4770	biotin carboxylase activity
CIT39_RS13925	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CIT39_RS13980	COG2373	Large extracellular alpha-helical protein
CIT39_RS13985	COG4953	penicillin-binding protein 1C
CIT39_RS13995	COG0671	phosphoesterase, PA-phosphatase related
CIT39_RS14000	COG0463	Glycosyl transferase, family 2
CIT39_RS14010	COG1309	transcriptional regulator
CIT39_RS14020	COG1283	sodium-dependent phosphate transmembrane transporter activity
CIT39_RS14025	COG0626	cystathionine gamma-synthase activity
CIT39_RS14030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CIT39_RS14035	COG4597	amino acid ABC transporter
CIT39_RS14040	COG0765	amino acid transport
CIT39_RS14045	COG1126	abc transporter atp-binding protein
CIT39_RS14090	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CIT39_RS14140	COG1126	abc transporter atp-binding protein
CIT39_RS14155	COG0251	oxidation-reduction process
CIT39_RS14170	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CIT39_RS14185	COG0525	valine-tRNA ligase activity
CIT39_RS14190	COG2094	Belongs to the DNA glycosylase MPG family
CIT39_RS14195	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CIT39_RS14200	COG2867	negative regulation of translational initiation
CIT39_RS14205	COG2863	cytochrome
CIT39_RS14210	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CIT39_RS14220	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CIT39_RS14220	COG2010	Cytochrome c
CIT39_RS14225	COG2863	cytochrome
CIT39_RS14235	COG0668	transmembrane transport
CIT39_RS14240	COG1546	Belongs to the CinA family
CIT39_RS14240	COG1058	Belongs to the CinA family
CIT39_RS14245	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CIT39_RS14245	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CIT39_RS14265	COG5000	phosphorelay sensor kinase activity
CIT39_RS14270	COG2204	response regulator
CIT39_RS14275	COG1923	regulation of RNA biosynthetic process
CIT39_RS14280	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CIT39_RS14285	COG3956	TIGRFAM MazG family protein
CIT39_RS14290	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CIT39_RS14310	COG1024	Enoyl-CoA hydratase
CIT39_RS14330	COG4774	siderophore transport
CIT39_RS14345	COG4178	(ABC) transporter
CIT39_RS14365	COG3237	CsbD-like
CIT39_RS14390	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CIT39_RS14395	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CIT39_RS14400	COG0318	PFAM AMP-dependent synthetase and ligase
CIT39_RS14420	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CIT39_RS14420	COG0321	lipoyl(octanoyl) transferase activity
CIT39_RS14425	COG0084	hydrolase, TatD family'
CIT39_RS14445	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CIT39_RS14450	COG1686	Belongs to the peptidase S11 family
CIT39_RS14455	COG2267	carboxylic ester hydrolase activity
CIT39_RS14500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CIT39_RS14520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CIT39_RS14530	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CIT39_RS14605	COG0129	dihydroxy-acid dehydratase activity
CIT39_RS14610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CIT39_RS14615	COG0601	transmembrane transport
CIT39_RS14625	COG0444	Belongs to the ABC transporter superfamily
CIT39_RS14645	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CIT39_RS14645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CIT39_RS14655	COG1335	isochorismatase
CIT39_RS14685	COG1175	transmembrane transport
CIT39_RS14690	COG0395	ABC-type sugar transport system, permease component
CIT39_RS14735	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CIT39_RS14735	COG0473	3-isopropylmalate dehydrogenase activity
CIT39_RS14745	COG1984	allophanate hydrolase subunit 2
CIT39_RS14750	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CIT39_RS14760	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CIT39_RS14765	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CIT39_RS14770	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CIT39_RS14770	COG1116	anion transmembrane transporter activity
CIT39_RS14775	COG3707	response regulator
CIT39_RS14780	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CIT39_RS14785	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CIT39_RS14790	COG0789	Transcriptional regulator
CIT39_RS14805	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CIT39_RS14815	COG1253	flavin adenine dinucleotide binding
CIT39_RS14820	COG1183	phosphatidylcholine synthase activity
CIT39_RS14825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CIT39_RS14830	COG0679	Auxin Efflux Carrier
CIT39_RS14870	COG1278	Cold shock
CIT39_RS14875	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CIT39_RS14890	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CIT39_RS14905	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CIT39_RS14915	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CIT39_RS14925	COG1285	pathogenesis
CIT39_RS15105	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CIT39_RS15125	COG0628	permease
CIT39_RS15140	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CIT39_RS15170	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CIT39_RS15215	COG0343	queuine tRNA-ribosyltransferase activity
CIT39_RS15225	COG1309	transcriptional regulator
CIT39_RS15235	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CIT39_RS15240	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CIT39_RS15260	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CIT39_RS15270	COG3158	transport of potassium into the cell
CIT39_RS15275	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CIT39_RS15280	COG0629	single-stranded DNA binding
CIT39_RS15290	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CIT39_RS15300	COG0546	phosphoglycolate phosphatase activity
CIT39_RS15395	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CIT39_RS15405	COG2340	Cysteine-rich secretory protein family
CIT39_RS15425	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CIT39_RS15445	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CIT39_RS15450	COG1862	Preprotein translocase
CIT39_RS15465	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CIT39_RS15475	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CIT39_RS15485	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CIT39_RS15495	COG0805	protein transport
CIT39_RS15500	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CIT39_RS15505	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CIT39_RS15510	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CIT39_RS15515	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CIT39_RS15520	COG1472	Belongs to the glycosyl hydrolase 3 family
CIT39_RS15530	COG0018	arginyl-trna synthetase
CIT39_RS15535	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CIT39_RS15615	COG2198	Histidine kinase
CIT39_RS15615	COG0784	Response regulator, receiver
CIT39_RS15615	COG5002	protein histidine kinase activity
CIT39_RS15620	COG0708	Exodeoxyribonuclease III
CIT39_RS15625	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CIT39_RS15650	COG4771	TonB-dependent receptor
CIT39_RS15700	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CIT39_RS15705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CIT39_RS15715	COG0508	dehydrogenase complex catalyzes the overall conversion of
CIT39_RS15730	COG0508	dehydrogenase complex catalyzes the overall conversion of
CIT39_RS15730	COG0022	dehydrogenase e1 component
CIT39_RS15735	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CIT39_RS15745	COG0431	NADPH-dependent FMN reductase
CIT39_RS15755	COG2207	Transcriptional regulator
CIT39_RS15760	COG4221	oxidoreductase activity
CIT39_RS15770	COG0148	phosphopyruvate hydratase activity
CIT39_RS15775	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CIT39_RS15790	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CIT39_RS15800	COG0745	RESPONSE REGULATOR receiver
CIT39_RS15810	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CIT39_RS15815	COG0504	CTP synthase activity
CIT39_RS15825	COG0149	triose-phosphate isomerase activity
CIT39_RS15835	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CIT39_RS15840	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CIT39_RS15845	COG0134	indole-3-glycerol-phosphate synthase activity
CIT39_RS15850	COG0315	cyclic pyranopterin monophosphate synthase activity
CIT39_RS15855	COG3300	MHYT domain
CIT39_RS15855	COG5001	Diguanylate cyclase
CIT39_RS15860	COG0793	Belongs to the peptidase S41A family
CIT39_RS15865	COG1304	FMN binding
CIT39_RS15870	COG1011	Hydrolase
CIT39_RS15880	COG0303	'Molybdopterin
CIT39_RS15885	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CIT39_RS15910	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CIT39_RS15915	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CIT39_RS15920	COG0372	Belongs to the citrate synthase family
CIT39_RS15935	COG1175	transmembrane transport
CIT39_RS15940	COG0395	ABC-type sugar transport system, permease component
CIT39_RS15950	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS15965	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CIT39_RS15975	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CIT39_RS15985	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CIT39_RS15990	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CIT39_RS15995	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CIT39_RS16000	COG0750	zinc metalloprotease
CIT39_RS16005	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CIT39_RS16015	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CIT39_RS16020	COG0233	cytoplasmic translational termination
CIT39_RS16025	COG0528	UMP kinase activity
CIT39_RS16030	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CIT39_RS16035	COG0052	Belongs to the universal ribosomal protein uS2 family
CIT39_RS16075	COG2814	Major facilitator Superfamily
CIT39_RS16085	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CIT39_RS16090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CIT39_RS16095	COG0024	Methionine aminopeptidase
CIT39_RS16110	COG1136	(ABC) transporter
CIT39_RS16120	COG0442	prolyl-tRNA aminoacylation
CIT39_RS16150	COG4774	siderophore transport
CIT39_RS16170	COG1129	ABC transporter
CIT39_RS16175	COG1172	Belongs to the binding-protein-dependent transport system permease family
CIT39_RS16195	COG0346	lactoylglutathione lyase activity
CIT39_RS16205	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CIT39_RS16205	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CIT39_RS16210	COG1007	ATP synthesis coupled electron transport
CIT39_RS16225	COG0713	ATP synthesis coupled electron transport
CIT39_RS16235	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CIT39_RS16240	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CIT39_RS16250	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CIT39_RS16260	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CIT39_RS16270	COG0649	NAD binding
CIT39_RS16280	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CIT39_RS16290	COG4774	siderophore transport
CIT39_RS16310	COG2195	Cleaves the N-terminal amino acid of tripeptides
CIT39_RS16315	COG1960	acyl-CoA dehydrogenase activity
CIT39_RS16355	COG2226	methyltransferase
CIT39_RS16370	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CIT39_RS16375	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CIT39_RS16385	COG0740	serine-type endopeptidase activity
CIT39_RS16390	COG0544	peptidyl-prolyl cis-trans isomerase activity
CIT39_RS16405	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CIT39_RS16405	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CIT39_RS16410	COG0347	Belongs to the P(II) protein family
CIT39_RS16415	COG0174	glutamine synthetase
CIT39_RS16460	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CIT39_RS16490	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CIT39_RS16495	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CIT39_RS16505	COG1024	Enoyl-CoA hydratase
CIT39_RS16525	COG1612	heme a metabolic process
CIT39_RS16550	COG0297	glycogen (starch) synthase activity
CIT39_RS16565	COG1846	Transcriptional regulator
CIT39_RS16570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CIT39_RS16575	COG3268	Saccharopine dehydrogenase
CIT39_RS16580	COG3268	Saccharopine dehydrogenase
CIT39_RS16660	COG0776	regulation of translation
CIT39_RS16665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CIT39_RS16670	COG0416	fatty acid biosynthetic process
CIT39_RS16700	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CIT39_RS16705	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CIT39_RS16710	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CIT39_RS16715	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CIT39_RS16725	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CIT39_RS16725	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CIT39_RS16730	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CIT39_RS16735	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CIT39_RS16760	COG0113	porphobilinogen synthase activity
CIT39_RS16770	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CIT39_RS16795	COG1914	H( )-stimulated, divalent metal cation uptake system
CIT39_RS16830	COG0697	spore germination
CIT39_RS16890	COG0747	negative chemotaxis
CIT39_RS16895	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CIT39_RS16905	COG1381	Involved in DNA repair and RecF pathway recombination
CIT39_RS16915	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CIT39_RS16920	COG0571	ribonuclease III activity
CIT39_RS16925	COG0681	Belongs to the peptidase S26 family
CIT39_RS16930	COG0736	holo-[acyl-carrier-protein] synthase activity
CIT39_RS16935	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CIT39_RS16945	COG1758	RNA polymerase activity
CIT39_RS16965	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CIT39_RS16970	COG1970	mechanosensitive ion channel activity
CIT39_RS16975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CIT39_RS17015	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CIT39_RS17025	COG0154	amidase activity
CIT39_RS17035	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CIT39_RS17040	COG2070	2-Nitropropane dioxygenase
CIT39_RS17050	COG0583	DNA-binding transcription factor activity
CIT39_RS17055	COG1864	DNA RNA non-specific endonuclease
CIT39_RS17055	COG3591	Belongs to the peptidase S1B family
CIT39_RS17065	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CIT39_RS17080	COG1960	acyl-CoA dehydrogenase activity
CIT39_RS17090	COG0540	Belongs to the ATCase OTCase family
CIT39_RS17100	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CIT39_RS17110	COG0154	amidase activity
CIT39_RS17115	COG0758	DNA mediated transformation
CIT39_RS17120	COG1733	regulation of RNA biosynthetic process
CIT39_RS17125	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CIT39_RS17130	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS17145	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CIT39_RS17150	COG0557	exoribonuclease II activity
CIT39_RS17170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CIT39_RS17175	COG4115	mRNA cleavage
CIT39_RS17180	COG2161	toxin-antitoxin pair type II binding
CIT39_RS17185	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CIT39_RS17220	COG0583	DNA-binding transcription factor activity
CIT39_RS17255	COG0784	Response regulator, receiver
CIT39_RS17265	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CIT39_RS17300	COG0537	adenosine 5'-monophosphoramidase activity
CIT39_RS17305	COG1720	tRNA m6t6A37 methyltransferase activity
CIT39_RS17350	COG1482	cell wall glycoprotein biosynthetic process
CIT39_RS17375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CIT39_RS17385	COG0840	transmembrane signaling receptor activity
CIT39_RS17390	COG0667	Aldo Keto reductase
CIT39_RS17415	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CIT39_RS17430	COG1686	Belongs to the peptidase S11 family
CIT39_RS17450	COG1192	Involved in chromosome partitioning
CIT39_RS17455	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CIT39_RS17505	COG2239	Acts as a magnesium transporter
CIT39_RS17540	COG4977	sequence-specific DNA binding
CIT39_RS17600	COG0523	cobalamin synthesis protein
CIT39_RS17620	COG0321	lipoyl(octanoyl) transferase activity
CIT39_RS17650	COG1254	Belongs to the acylphosphatase family
CIT39_RS17655	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CIT39_RS17660	COG4770	biotin carboxylase activity
CIT39_RS17690	COG2271	Major facilitator Superfamily
CIT39_RS17700	COG4948	Mandelate Racemase Muconate Lactonizing
CIT39_RS17705	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS17710	COG1063	alcohol dehydrogenase
CIT39_RS17725	COG2197	response regulator
CIT39_RS17730	COG1234	tRNA 3'-trailer cleavage
CIT39_RS17740	COG1414	Transcriptional regulator
CIT39_RS17745	COG2124	cytochrome p450
CIT39_RS17755	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CIT39_RS17760	COG0179	Fumarylacetoacetate (FAA) hydrolase
CIT39_RS17780	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CIT39_RS17830	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS17875	COG4566	intracellular signal transduction
CIT39_RS17880	COG1566	PFAM secretion protein HlyD family protein
CIT39_RS17885	COG1136	(ABC) transporter
CIT39_RS17885	COG0577	efflux transmembrane transporter activity
CIT39_RS17890	COG1136	(ABC) transporter
CIT39_RS17890	COG0577	efflux transmembrane transporter activity
CIT39_RS17895	COG2197	response regulator
CIT39_RS17920	COG0450	alkyl hydroperoxide reductase
CIT39_RS17925	COG0415	Belongs to the DNA photolyase family
CIT39_RS17970	COG0583	DNA-binding transcription factor activity
CIT39_RS18030	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS18035	COG2030	dehydratase
CIT39_RS18055	COG2010	Cytochrome c
CIT39_RS18055	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CIT39_RS18060	COG2860	membrane
CIT39_RS18130	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CIT39_RS18155	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CIT39_RS18180	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CIT39_RS18185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CIT39_RS18195	COG1733	regulation of RNA biosynthetic process
CIT39_RS18210	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS18220	COG0203	ribosomal protein L17
CIT39_RS18225	COG0202	RNA polymerase activity
CIT39_RS18230	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CIT39_RS18235	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CIT39_RS18240	COG0563	adenylate kinase activity
CIT39_RS18250	COG0200	Binds to the 23S rRNA
CIT39_RS18255	COG1841	ribosomal large subunit assembly
CIT39_RS18260	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CIT39_RS18265	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CIT39_RS18270	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CIT39_RS18275	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CIT39_RS18280	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CIT39_RS18285	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CIT39_RS18290	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CIT39_RS18295	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CIT39_RS18300	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CIT39_RS18305	COG0255	Belongs to the universal ribosomal protein uL29 family
CIT39_RS18310	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CIT39_RS18315	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CIT39_RS18320	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CIT39_RS18325	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CIT39_RS18330	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CIT39_RS18335	COG0089	rRNA binding
CIT39_RS18340	COG0088	Forms part of the polypeptide exit tunnel
CIT39_RS18345	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CIT39_RS18350	COG0051	transcription antitermination factor activity, RNA binding
CIT39_RS18355	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CIT39_RS18360	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CIT39_RS18365	COG0049	tRNA binding
CIT39_RS18370	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CIT39_RS18380	COG1132	(ABC) transporter
CIT39_RS18385	COG1231	oxidoreductase activity
CIT39_RS18390	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CIT39_RS18395	COG0085	RNA polymerase activity
CIT39_RS18400	COG0222	ribosome binding
CIT39_RS18405	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CIT39_RS18410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIT39_RS18415	COG0081	regulation of translation
CIT39_RS18420	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CIT39_RS18430	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CIT39_RS18450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CIT39_RS18455	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CIT39_RS18455	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CIT39_RS18460	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CIT39_RS18475	COG3959	Transketolase, thiamine diphosphate binding domain
CIT39_RS18480	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CIT39_RS18505	COG2226	methyltransferase
CIT39_RS18540	COG0673	inositol 2-dehydrogenase activity
CIT39_RS18580	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS18585	COG0406	alpha-ribazole phosphatase activity
CIT39_RS18590	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS18610	COG1960	acyl-CoA dehydrogenase activity
CIT39_RS18615	COG1309	transcriptional regulator
CIT39_RS18630	COG3246	L-lysine catabolic process to acetate
CIT39_RS18665	COG0662	Cupin 2, conserved barrel domain protein
CIT39_RS18685	COG0829	nickel cation binding
CIT39_RS18690	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CIT39_RS18695	COG0804	urea catabolic process
CIT39_RS18700	COG0832	Belongs to the urease beta subunit family
CIT39_RS18700	COG0831	urea catabolic process
CIT39_RS18705	COG0830	nickel cation binding
CIT39_RS18710	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CIT39_RS18780	COG3795	YCII-related domain
CIT39_RS18800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CIT39_RS18820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CIT39_RS18920	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CIT39_RS18945	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CIT39_RS18950	COG0302	gtp cyclohydrolase
CIT39_RS18965	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CIT39_RS18985	COG0477	Major facilitator Superfamily
CIT39_RS19000	COG0531	amino acid
CIT39_RS19020	COG2814	Major facilitator Superfamily
CIT39_RS19025	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CIT39_RS19040	COG5001	Diguanylate cyclase
CIT39_RS19090	COG1752	Esterase of the alpha-beta hydrolase superfamily
CIT39_RS19095	COG0517	IMP dehydrogenase activity
CIT39_RS19150	COG1063	alcohol dehydrogenase
CIT39_RS19185	COG3842	ATPase activity
CIT39_RS19195	COG1176	ABC-type spermidine putrescine transport system, permease component I
CIT39_RS19200	COG3833	ABC-type maltose transport systems, permease component
CIT39_RS19270	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CIT39_RS19285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CIT39_RS19320	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CIT39_RS19335	COG0747	negative chemotaxis
CIT39_RS19350	COG0601	transmembrane transport
CIT39_RS19355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CIT39_RS19360	COG4172	Belongs to the ABC transporter superfamily
CIT39_RS19370	COG1473	amidohydrolase
CIT39_RS19375	COG0154	amidase activity
CIT39_RS19380	COG1024	Enoyl-CoA hydratase
CIT39_RS19385	COG3321	synthase
CIT39_RS19385	COG0604	alcohol dehydrogenase
CIT39_RS19395	COG0625	glutathione transferase activity
CIT39_RS19410	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CIT39_RS19415	COG1546	Belongs to the CinA family
CIT39_RS19415	COG1058	Belongs to the CinA family
CIT39_RS19420	COG2308	Evidence 4 Homologs of previously reported genes of
CIT39_RS19430	COG1305	Transglutaminase-like
CIT39_RS19455	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CIT39_RS19480	COG5425	PFAM Usg family protein
CIT39_RS19485	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CIT39_RS19490	COG0459	protein refolding
CIT39_RS19500	COG0681	Belongs to the peptidase S26 family
CIT39_RS19515	COG0625	glutathione transferase activity
CIT39_RS19570	COG0384	phenazine biosynthesis protein PhzF
CIT39_RS19580	COG0842	Transport permease protein
CIT39_RS19585	COG1131	(ABC) transporter
CIT39_RS19600	COG0640	Transcriptional regulator
CIT39_RS19635	COG3608	succinylglutamate desuccinylase aspartoacylase
CIT39_RS19635	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CIT39_RS19670	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CIT39_RS19675	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CIT39_RS19680	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CIT39_RS19720	COG2204	response regulator
CIT39_RS19725	COG4191	Histidine kinase
CIT39_RS19725	COG0784	Response regulator, receiver
CIT39_RS19760	COG0515	serine threonine protein kinase
CIT39_RS19760	COG2815	serine threonine protein kinase
CIT39_RS19800	COG1309	transcriptional regulator
CIT39_RS19805	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CIT39_RS19810	COG1473	amidohydrolase
CIT39_RS19820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CIT39_RS19825	COG5001	Diguanylate cyclase
CIT39_RS19830	COG0318	PFAM AMP-dependent synthetase and ligase
CIT39_RS19835	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CIT39_RS19870	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CIT39_RS19890	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CIT39_RS19895	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CIT39_RS19900	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CIT39_RS19905	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CIT39_RS19940	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CIT39_RS19955	COG0047	phosphoribosylformylglycinamidine synthase activity
CIT39_RS19960	COG0598	Magnesium transport protein CorA
CIT39_RS19965	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CIT39_RS19970	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CIT39_RS19980	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
CIT39_RS19985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CIT39_RS19985	COG1116	anion transmembrane transporter activity
CIT39_RS19990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CIT39_RS19995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CIT39_RS20015	COG1309	transcriptional regulator
CIT39_RS20020	COG2267	carboxylic ester hydrolase activity
CIT39_RS20025	COG2020	methyltransferase activity
CIT39_RS20035	COG0604	alcohol dehydrogenase
CIT39_RS20055	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CIT39_RS20060	COG0538	isocitrate dehydrogenase activity
CIT39_RS20075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CIT39_RS20080	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CIT39_RS20085	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CIT39_RS20090	COG0509	glycine decarboxylation via glycine cleavage system
CIT39_RS20095	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CIT39_RS20095	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CIT39_RS20100	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CIT39_RS20165	COG4993	Dehydrogenase
CIT39_RS20200	COG0640	Transcriptional regulator
CIT39_RS20205	COG0446	pyridine nucleotide-disulphide oxidoreductase
CIT39_RS20310	COG2917	probably involved in intracellular septation
CIT39_RS20325	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CIT39_RS20325	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CIT39_RS20365	COG1684	flagellar biosynthetic protein fliR
CIT39_RS20370	COG1987	bacterial-type flagellum assembly
CIT39_RS20375	COG1677	Flagellar hook-basal body complex protein FliE
CIT39_RS20380	COG1558	bacterial-type flagellum-dependent cell motility
CIT39_RS20395	COG1338	Plays a role in the flagellum-specific transport system
CIT39_RS20425	COG4786	Flagellar basal body rod
CIT39_RS20430	COG4786	Flagellar basal body rod
CIT39_RS20440	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CIT39_RS20445	COG3971	2-oxopent-4-enoate hydratase activity
CIT39_RS20450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CIT39_RS20455	COG1733	regulation of RNA biosynthetic process
CIT39_RS20465	COG2910	NAD(P)H-binding
CIT39_RS20470	COG1733	regulation of RNA biosynthetic process
CIT39_RS20480	COG1706	bacterial-type flagellum-dependent cell motility
CIT39_RS20500	COG5442	Flagellar protein FlaF
CIT39_RS20505	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CIT39_RS20510	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CIT39_RS20515	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CIT39_RS20520	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CIT39_RS20525	COG5443	negative regulation of bacterial-type flagellum assembly
CIT39_RS20530	COG0076	glutamate decarboxylase activity
CIT39_RS20560	COG1749	Flagellar hook protein flgE
CIT39_RS20565	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CIT39_RS20570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CIT39_RS20605	COG2267	carboxylic ester hydrolase activity
CIT39_RS20620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CIT39_RS20635	COG3300	MHYT domain
CIT39_RS20635	COG5001	Diguanylate cyclase
CIT39_RS20640	COG3685	Protein conserved in bacteria
CIT39_RS20660	COG0583	DNA-binding transcription factor activity
CIT39_RS20665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CIT39_RS20675	COG1012	belongs to the aldehyde dehydrogenase family
CIT39_RS20680	COG2721	sulfolactate sulfo-lyase activity
CIT39_RS20700	COG0492	ferredoxin-NADP+ reductase activity
CIT39_RS20710	COG0633	Ferredoxin
CIT39_RS20740	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CIT39_RS20740	COG3218	ABC-type transport auxiliary lipoprotein component
CIT39_RS20745	COG1127	ABC transporter
CIT39_RS20750	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CIT39_RS20755	COG4948	Mandelate Racemase Muconate Lactonizing
CIT39_RS20760	COG2814	Major facilitator Superfamily
CIT39_RS20780	COG4154	Belongs to the RbsD FucU family
CIT39_RS20805	COG0351	phosphomethylpyrimidine kinase
CIT39_RS20815	COG2010	Cytochrome c
CIT39_RS20830	COG3909	cytochrome
CIT39_RS20860	COG0673	inositol 2-dehydrogenase activity
CIT39_RS20865	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CIT39_RS20865	COG0662	Cupin 2, conserved barrel domain protein
CIT39_RS20880	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CIT39_RS20905	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CIT39_RS20905	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CIT39_RS20915	COG0859	PFAM glycosyl transferase family 9
CIT39_RS20930	COG1132	(ABC) transporter
CIT39_RS20950	COG0583	DNA-binding transcription factor activity
CIT39_RS20955	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS20975	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CIT39_RS20980	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CIT39_RS20995	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CIT39_RS21005	COG1137	ATPase activity
CIT39_RS21050	COG4191	Histidine kinase
CIT39_RS21050	COG0784	Response regulator, receiver
CIT39_RS21055	COG3920	Histidine kinase
CIT39_RS21070	COG0318	PFAM AMP-dependent synthetase and ligase
CIT39_RS21095	COG2942	2-epimerase
CIT39_RS21100	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CIT39_RS21105	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CIT39_RS21105	COG2755	lipolytic protein G-D-S-L family
CIT39_RS21110	COG2192	nodulation
CIT39_RS21120	COG2089	acid synthase
CIT39_RS21125	COG1083	cytidylyl-transferase
CIT39_RS21130	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS21140	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS21145	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS21180	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CIT39_RS21185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CIT39_RS21190	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CIT39_RS21195	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CIT39_RS21200	COG2089	acid synthase
CIT39_RS21210	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CIT39_RS21220	COG1083	cytidylyl-transferase
CIT39_RS21225	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS21255	COG1215	transferase activity, transferring glycosyl groups
CIT39_RS21265	COG0463	Glycosyl transferase, family 2
CIT39_RS21270	COG3958	Transketolase
CIT39_RS21275	COG3959	Transketolase, thiamine diphosphate binding domain
CIT39_RS21300	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CIT39_RS21305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CIT39_RS21325	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CIT39_RS21330	COG2226	methyltransferase
CIT39_RS21350	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CIT39_RS21360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CIT39_RS21365	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CIT39_RS21370	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CIT39_RS21390	COG1024	Enoyl-CoA hydratase
CIT39_RS21395	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CIT39_RS21400	COG0247	lactate metabolic process
CIT39_RS21400	COG0277	FAD linked oxidase domain protein
CIT39_RS21410	COG1024	Enoyl-CoA hydratase
CIT39_RS21420	COG0243	molybdopterin cofactor binding
CIT39_RS21425	COG3181	Tripartite tricarboxylate transporter family receptor
CIT39_RS21430	COG2080	2 iron, 2 sulfur cluster binding
CIT39_RS21435	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CIT39_RS21435	COG2010	Cytochrome c
CIT39_RS21445	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS21460	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CIT39_RS21465	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CIT39_RS21475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CIT39_RS21480	COG2010	Cytochrome c
CIT39_RS21485	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CIT39_RS21485	COG3218	ABC-type transport auxiliary lipoprotein component
CIT39_RS21490	COG1127	ABC transporter
CIT39_RS21510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CIT39_RS21510	COG0045	succinate-CoA ligase (ADP-forming) activity
CIT39_RS21510	COG1042	CoA-binding domain protein
CIT39_RS21535	COG3243	poly(R)-hydroxyalkanoic acid synthase
CIT39_RS21540	COG0517	IMP dehydrogenase activity
CIT39_RS21540	COG0617	tRNA 3'-terminal CCA addition
CIT39_RS21540	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CIT39_RS21545	COG0251	oxidation-reduction process
CIT39_RS21580	COG1024	Enoyl-CoA hydratase
CIT39_RS21585	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS21595	COG1960	acyl-CoA dehydrogenase activity
CIT39_RS21600	COG0318	PFAM AMP-dependent synthetase and ligase
CIT39_RS21610	COG1250	3-hydroxyacyl-CoA dehydrogenase
CIT39_RS21620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CIT39_RS21625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CIT39_RS21635	COG0129	dihydroxy-acid dehydratase activity
CIT39_RS21645	COG2084	Dehydrogenase
CIT39_RS21650	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CIT39_RS21700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CIT39_RS21720	COG0454	-acetyltransferase
CIT39_RS21745	COG2200	EAL domain
CIT39_RS21775	COG2197	response regulator
CIT39_RS21795	COG0010	Belongs to the arginase family
CIT39_RS21805	COG5001	Diguanylate cyclase
CIT39_RS21805	COG3300	MHYT domain
CIT39_RS21825	COG2010	Cytochrome c
CIT39_RS21895	COG1301	dicarboxylic acid transport
CIT39_RS21920	COG3845	ABC transporter
CIT39_RS21925	COG4603	Belongs to the binding-protein-dependent transport system permease family
CIT39_RS21930	COG1079	Belongs to the binding-protein-dependent transport system permease family
CIT39_RS21950	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CIT39_RS21950	COG2080	2 iron, 2 sulfur cluster binding
CIT39_RS21995	COG0235	Class ii aldolase
CIT39_RS22000	COG2095	MarC family integral membrane protein
CIT39_RS22020	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CIT39_RS22030	COG0183	Belongs to the thiolase family
CIT39_RS22035	COG2723	6-phospho-beta-galactosidase activity
CIT39_RS22050	COG4771	TonB-dependent receptor
CIT39_RS22060	COG2197	response regulator
CIT39_RS22065	COG3851	Histidine kinase
CIT39_RS22070	COG2197	response regulator
CIT39_RS22075	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CIT39_RS22095	COG1131	(ABC) transporter
CIT39_RS22150	COG1116	anion transmembrane transporter activity
CIT39_RS22215	COG3119	arylsulfatase activity
CIT39_RS22245	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CIT39_RS22250	COG3791	Glutathione-dependent formaldehyde-activating
CIT39_RS22275	COG0723	plastoquinol--plastocyanin reductase activity
CIT39_RS22285	COG1250	3-hydroxyacyl-CoA dehydrogenase
CIT39_RS22370	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CIT39_RS22375	COG2986	histidine ammonia-lyase
CIT39_RS22380	COG1228	amidohydrolase
CIT39_RS22400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CIT39_RS22405	COG1116	anion transmembrane transporter activity
CIT39_RS22415	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CIT39_RS22435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CIT39_RS22440	COG1136	(ABC) transporter
CIT39_RS22440	COG0577	efflux transmembrane transporter activity
CIT39_RS22455	COG2223	nitrite transmembrane transporter activity
CIT39_RS22465	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CIT39_RS22475	COG1764	response to oxidative stress
CIT39_RS22485	COG0596	Alpha beta hydrolase
CIT39_RS22510	COG2267	carboxylic ester hydrolase activity
CIT39_RS22515	COG0596	Alpha beta hydrolase
CIT39_RS22525	COG2169	Transcriptional regulator
CIT39_RS22540	COG3685	Protein conserved in bacteria
CIT39_RS22580	COG5564	TIM-barrel signal transduction protein
CIT39_RS22585	COG2268	Band 7 protein
CIT39_RS22585	COG2268	Band 7 protein
CIT39_RS22630	COG3618	amidohydrolase
CIT39_RS22640	COG3386	PFAM SMP-30 Gluconolaconase
CIT39_RS22645	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CIT39_RS22660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CIT39_RS22670	COG0531	amino acid
CIT39_RS22675	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS22685	COG0235	Class ii aldolase
CIT39_RS22705	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CIT39_RS22715	COG3842	ATPase activity
CIT39_RS22720	COG1176	ABC-type spermidine putrescine transport system, permease component I
CIT39_RS22730	COG1414	Transcriptional regulator
CIT39_RS22740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CIT39_RS22745	COG1136	(ABC) transporter
CIT39_RS22755	COG0577	efflux transmembrane transporter activity
CIT39_RS22755	COG1136	(ABC) transporter
CIT39_RS22780	COG0604	alcohol dehydrogenase
CIT39_RS22780	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS22780	COG3321	synthase
CIT39_RS22800	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CIT39_RS22805	COG1902	pentaerythritol trinitrate reductase activity
CIT39_RS22820	COG1902	pentaerythritol trinitrate reductase activity
CIT39_RS22835	COG1024	Enoyl-CoA hydratase
CIT39_RS22840	COG1960	acyl-CoA dehydrogenase activity
CIT39_RS22850	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CIT39_RS22890	COG1024	Enoyl-CoA hydratase
CIT39_RS22930	COG0778	Nitroreductase
CIT39_RS22955	COG0574	Belongs to the PEP-utilizing enzyme family
CIT39_RS22955	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CIT39_RS22965	COG2723	6-phospho-beta-galactosidase activity
CIT39_RS22970	COG0837	glucose binding
CIT39_RS23000	COG4178	(ABC) transporter
CIT39_RS23005	COG4178	(ABC) transporter
CIT39_RS23020	COG0071	Belongs to the small heat shock protein (HSP20) family
CIT39_RS23065	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CIT39_RS23120	COG0673	inositol 2-dehydrogenase activity
CIT39_RS23125	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CIT39_RS23135	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CIT39_RS23140	COG0297	glycogen (starch) synthase activity
CIT39_RS23145	COG4095	Psort location CytoplasmicMembrane, score
CIT39_RS23150	COG3384	dioxygenase
CIT39_RS23170	COG2072	flavoprotein involved in K transport
CIT39_RS23185	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CIT39_RS23190	COG0281	malic enzyme
CIT39_RS23195	COG0668	transmembrane transport
CIT39_RS23205	COG2326	polyphosphate kinase activity
CIT39_RS23265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CIT39_RS23275	COG0517	IMP dehydrogenase activity
CIT39_RS23275	COG1125	glycine betaine transport
CIT39_RS23280	COG1174	glycine betaine transport
CIT39_RS23305	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS23310	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CIT39_RS23330	COG0440	acetolactate synthase activity
CIT39_RS23335	COG0028	Belongs to the TPP enzyme family
CIT39_RS23340	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CIT39_RS23360	COG0330	HflC and HflK could
CIT39_RS23365	COG0330	HflC and HflK could
CIT39_RS23380	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CIT39_RS23420	COG0114	fumarate hydratase activity
CIT39_RS23475	COG3258	Cytochrome c
CIT39_RS23490	COG2202	Pas domain
CIT39_RS23490	COG3920	Histidine kinase
CIT39_RS23495	COG4191	Histidine kinase
CIT39_RS23495	COG0784	Response regulator, receiver
CIT39_RS23515	COG2124	cytochrome p450
CIT39_RS23520	COG1309	transcriptional regulator
CIT39_RS23555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CIT39_RS23560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CIT39_RS23565	COG2202	Pas domain
CIT39_RS23565	COG2200	EAL domain
CIT39_RS23565	COG2199	diguanylate cyclase activity
CIT39_RS23570	COG2271	Major facilitator Superfamily
CIT39_RS23575	COG3300	MHYT domain
CIT39_RS23575	COG5001	Diguanylate cyclase
CIT39_RS23585	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CIT39_RS23595	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CIT39_RS23615	COG0277	FAD linked oxidase domain protein
CIT39_RS23625	COG5487	UPF0391 membrane protein
CIT39_RS23630	COG0210	DNA helicase
CIT39_RS23670	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CIT39_RS23700	COG1131	(ABC) transporter
CIT39_RS23705	COG0842	Transport permease protein
CIT39_RS23730	COG0584	glycerophosphoryl diester phosphodiesterase
CIT39_RS23750	COG2264	protein methyltransferase activity
CIT39_RS23760	COG0006	proline dipeptidase activity
CIT39_RS23760	COG0006	proline dipeptidase activity
CIT39_RS23765	COG2814	Major facilitator Superfamily
CIT39_RS23770	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CIT39_RS23780	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CIT39_RS23790	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CIT39_RS23795	COG0849	cell division
CIT39_RS23800	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CIT39_RS23805	COG1181	Belongs to the D-alanine--D-alanine ligase family
CIT39_RS23810	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CIT39_RS23815	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CIT39_RS23820	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CIT39_RS23835	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CIT39_RS23840	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CIT39_RS23845	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CIT39_RS23850	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CIT39_RS23865	COG0275	rRNA processing
CIT39_RS23870	COG3023	N-Acetylmuramoyl-L-alanine amidase
CIT39_RS23875	COG4941	Belongs to the sigma-70 factor family
CIT39_RS23880	COG3795	YCII-related domain
CIT39_RS23895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CIT39_RS23915	COG5265	(ABC) transporter
CIT39_RS23935	COG1309	transcriptional regulator
CIT39_RS23955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CIT39_RS23960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CIT39_RS23965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CIT39_RS23995	COG0688	phosphatidylethanolamine metabolic process
CIT39_RS24020	COG1376	ErfK ybiS ycfS ynhG family protein
CIT39_RS24020	COG1388	LysM domain
CIT39_RS24055	COG3842	ATPase activity
CIT39_RS24065	COG1176	ABC-type spermidine putrescine transport system, permease component I
CIT39_RS24120	COG2022	thiamine diphosphate biosynthetic process
CIT39_RS24130	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CIT39_RS24135	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CIT39_RS24150	COG0625	glutathione transferase activity
CIT39_RS24185	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS24190	COG2204	response regulator
CIT39_RS24215	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CIT39_RS24280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CIT39_RS24285	COG1376	ErfK ybiS ycfS ynhG family protein
CIT39_RS24295	COG2897	thiosulfate sulfurtransferase activity
CIT39_RS24300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CIT39_RS24315	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CIT39_RS24340	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CIT39_RS24355	COG4948	Mandelate Racemase Muconate Lactonizing
CIT39_RS24385	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CIT39_RS24390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CIT39_RS24395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CIT39_RS24400	COG0601	transmembrane transport
CIT39_RS24405	COG0747	negative chemotaxis
CIT39_RS24415	COG0784	Response regulator, receiver
CIT39_RS24415	COG4191	Histidine kinase
CIT39_RS24430	COG2072	flavoprotein involved in K transport
CIT39_RS24460	COG0475	glutathione-regulated potassium exporter activity
CIT39_RS24480	COG4948	Mandelate Racemase Muconate Lactonizing
CIT39_RS24490	COG0386	Belongs to the glutathione peroxidase family
CIT39_RS24495	COG0154	amidase activity
CIT39_RS24510	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CIT39_RS24515	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
CIT39_RS24520	COG0535	radical SAM domain protein
CIT39_RS24525	COG0535	radical SAM domain protein
CIT39_RS24545	COG0674	pyruvate-flavodoxin oxidoreductase activity
CIT39_RS24545	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CIT39_RS24550	COG1013	pyruvate-flavodoxin oxidoreductase activity
CIT39_RS24595	COG2719	SpoVR family
CIT39_RS24600	COG2718	Belongs to the UPF0229 family
CIT39_RS24605	COG2766	serine protein kinase
CIT39_RS24615	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CIT39_RS24620	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CIT39_RS24625	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CIT39_RS24630	COG0363	glucosamine-6-phosphate deaminase activity
CIT39_RS24635	COG3265	gluconokinase activity
CIT39_RS24645	COG3387	PFAM Glycoside hydrolase 15-related
CIT39_RS24650	COG1640	4-alpha-glucanotransferase
CIT39_RS24655	COG0366	Alpha amylase catalytic
CIT39_RS24660	COG0366	Alpha amylase catalytic
CIT39_RS24665	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CIT39_RS24675	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CIT39_RS24700	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CIT39_RS24705	COG0745	RESPONSE REGULATOR receiver
CIT39_RS24710	COG2205	protein histidine kinase activity
CIT39_RS24715	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CIT39_RS24720	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CIT39_RS24725	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CIT39_RS24750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CIT39_RS24800	COG1749	Flagellar hook protein flgE
CIT39_RS24820	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CIT39_RS24825	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CIT39_RS24830	COG1595	DNA-templated transcription, initiation
CIT39_RS24855	COG0427	acetyl-CoA hydrolase
CIT39_RS24875	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CIT39_RS24885	COG2030	dehydratase
CIT39_RS24910	COG1053	succinate dehydrogenase
CIT39_RS24915	COG1414	Transcriptional regulator
CIT39_RS24920	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS24930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CIT39_RS24935	COG0028	Belongs to the TPP enzyme family
CIT39_RS24940	COG1794	racemase activity, acting on amino acids and derivatives
CIT39_RS24965	COG0412	Dienelactone hydrolase
CIT39_RS25015	COG1684	flagellar biosynthetic protein fliR
CIT39_RS25020	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CIT39_RS25025	COG4794	Type iii secretion
CIT39_RS25030	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CIT39_RS25035	COG5443	negative regulation of bacterial-type flagellum assembly
CIT39_RS25055	COG1749	Flagellar hook protein flgE
CIT39_RS25075	COG1360	Flagellar Motor Protein
CIT39_RS25090	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CIT39_RS25095	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CIT39_RS25100	COG1338	Plays a role in the flagellum-specific transport system
CIT39_RS25110	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CIT39_RS25120	COG1706	bacterial-type flagellum-dependent cell motility
CIT39_RS25130	COG4786	Flagellar basal body rod
CIT39_RS25135	COG1677	Flagellar hook-basal body complex protein FliE
CIT39_RS25140	COG1558	bacterial-type flagellum-dependent cell motility
CIT39_RS25145	COG1815	bacterial-type flagellum-dependent cell motility
CIT39_RS25150	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CIT39_RS25155	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CIT39_RS25160	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CIT39_RS25175	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CIT39_RS25185	COG4786	Flagellar basal body rod
CIT39_RS25190	COG1157	protein secretion by the type III secretion system
CIT39_RS25195	COG1846	Transcriptional regulator
CIT39_RS25220	COG0411	ABC transporter
CIT39_RS25225	COG0559	Belongs to the binding-protein-dependent transport system permease family
CIT39_RS25245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CIT39_RS25275	COG1404	Belongs to the peptidase S8 family
CIT39_RS25325	COG0482	sulfurtransferase activity
CIT39_RS25335	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CIT39_RS25345	COG1766	The M ring may be actively involved in energy transduction
CIT39_RS25350	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CIT39_RS25360	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CIT39_RS25365	COG2204	response regulator
CIT39_RS25370	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CIT39_RS25375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CIT39_RS25390	COG1376	ErfK ybiS ycfS ynhG family protein
CIT39_RS25395	COG0745	RESPONSE REGULATOR receiver
CIT39_RS25410	COG2207	Transcriptional regulator
CIT39_RS25445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CIT39_RS25460	COG0243	molybdopterin cofactor binding
CIT39_RS25465	COG3043	anaerobic respiration
CIT39_RS25470	COG3005	denitrification pathway
CIT39_RS25480	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CIT39_RS25495	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CIT39_RS25500	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CIT39_RS25550	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CIT39_RS25555	COG1136	(ABC) transporter
CIT39_RS25560	COG4591	ABC-type transport system involved in lipoprotein release permease component
CIT39_RS25565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CIT39_RS25570	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CIT39_RS25595	COG0840	transmembrane signaling receptor activity
CIT39_RS25600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIT39_RS25610	COG1175	transmembrane transport
CIT39_RS25615	COG0395	ABC-type sugar transport system, permease component
CIT39_RS25620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CIT39_RS25635	COG0848	biopolymer transport protein
CIT39_RS25665	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CIT39_RS25670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CIT39_RS25675	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CIT39_RS25685	COG4566	intracellular signal transduction
CIT39_RS25710	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CIT39_RS25760	COG1175	transmembrane transport
CIT39_RS25770	COG1177	transmembrane transport
CIT39_RS25775	COG1176	ABC-type spermidine putrescine transport system, permease component I
CIT39_RS25780	COG3842	ATPase activity
CIT39_RS25790	COG5001	Diguanylate cyclase
CIT39_RS25790	COG3300	MHYT domain
CIT39_RS25795	COG0579	oxidoreductase
CIT39_RS25820	COG5001	Diguanylate cyclase
CIT39_RS25820	COG3447	MASE1 domain protein
CIT39_RS25820	COG5002	protein histidine kinase activity
CIT39_RS25825	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CIT39_RS25830	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CIT39_RS25835	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CIT39_RS25840	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CIT39_RS25860	COG0387	Pfam Sodium calcium exchanger
CIT39_RS25905	COG1164	Oligoendopeptidase f
CIT39_RS25910	COG2204	response regulator
CIT39_RS25915	COG2989	Protein conserved in bacteria
CIT39_RS25930	COG3750	Belongs to the UPF0335 family
CIT39_RS25945	COG0469	pyruvate kinase activity
CIT39_RS25950	COG1309	transcriptional regulator
CIT39_RS26000	COG0463	Glycosyl transferase, family 2
CIT39_RS26005	COG2226	methyltransferase
CIT39_RS26015	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CIT39_RS26020	COG0037	tRNA processing
CIT39_RS26030	COG2885	chlorophyll binding
CIT39_RS26040	COG5001	Diguanylate cyclase
CIT39_RS26045	COG0823	Involved in the tonB-independent uptake of proteins
CIT39_RS26065	COG1045	serine acetyltransferase
CIT39_RS26105	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS26130	COG4941	Belongs to the sigma-70 factor family
CIT39_RS26135	COG3795	YCII-related domain
CIT39_RS26145	COG1309	transcriptional regulator
CIT39_RS26150	COG0625	glutathione transferase activity
CIT39_RS26155	COG0840	transmembrane signaling receptor activity
CIT39_RS26190	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CIT39_RS26210	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS26220	COG1301	dicarboxylic acid transport
CIT39_RS26225	COG0488	(ABC) transporter
CIT39_RS26255	COG1177	transmembrane transport
CIT39_RS26260	COG1176	ABC-type spermidine putrescine transport system, permease component I
CIT39_RS26265	COG3842	ATPase activity
CIT39_RS26285	COG0402	S-adenosylhomocysteine deaminase activity
CIT39_RS26305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CIT39_RS26335	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CIT39_RS26335	COG0519	Catalyzes the synthesis of GMP from XMP
CIT39_RS26345	COG0824	Thioesterase
CIT39_RS26350	COG1408	metallophosphoesterase
CIT39_RS26355	COG2255	four-way junction helicase activity
CIT39_RS26360	COG0632	four-way junction helicase activity
CIT39_RS26365	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CIT39_RS26370	COG0217	transcriptional regulatory protein
CIT39_RS26380	COG0840	transmembrane signaling receptor activity
CIT39_RS26410	COG1692	metallophosphoesterase
CIT39_RS26445	COG0126	phosphoglycerate kinase activity
CIT39_RS26455	COG3588	fructose-bisphosphate aldolase
CIT39_RS26470	COG0483	inositol monophosphate 1-phosphatase activity
CIT39_RS26475	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CIT39_RS26485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CIT39_RS26490	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CIT39_RS26515	COG0659	secondary active sulfate transmembrane transporter activity
CIT39_RS26520	COG1132	(ABC) transporter
CIT39_RS26525	COG0254	rRNA binding
CIT39_RS26545	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS26545	COG3321	synthase
CIT39_RS26545	COG0604	alcohol dehydrogenase
CIT39_RS26560	COG5001	Diguanylate cyclase
CIT39_RS26560	COG4251	negative regulation of phosphorylation
CIT39_RS26560	COG2203	Gaf domain
CIT39_RS26560	COG3706	GGDEF domain
CIT39_RS26570	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CIT39_RS26575	COG2951	lytic endotransglycosylase activity
CIT39_RS26585	COG3237	CsbD-like
CIT39_RS26590	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS26595	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS26605	COG1678	Uncharacterized ACR, COG1678
CIT39_RS26620	COG0730	response to heat
CIT39_RS26630	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS26645	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CIT39_RS26650	COG4208	sulfate ABC transporter
CIT39_RS26655	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CIT39_RS26660	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CIT39_RS26665	COG0175	sulfate reduction
CIT39_RS26675	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CIT39_RS26685	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CIT39_RS26685	COG1648	precorrin-2 dehydrogenase activity
CIT39_RS26700	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CIT39_RS26715	COG1388	LysM domain
CIT39_RS26715	COG1376	ErfK ybiS ycfS ynhG family protein
CIT39_RS26745	COG4774	siderophore transport
CIT39_RS26765	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CIT39_RS26770	COG0830	nickel cation binding
CIT39_RS26790	COG0804	urea catabolic process
CIT39_RS26795	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CIT39_RS26800	COG0832	Belongs to the urease beta subunit family
CIT39_RS26805	COG0831	urea catabolic process
CIT39_RS26810	COG0829	nickel cation binding
CIT39_RS26840	COG0513	Belongs to the DEAD box helicase family
CIT39_RS26845	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CIT39_RS26850	COG1278	Cold shock
CIT39_RS26890	COG4964	Belongs to the GSP D family
CIT39_RS26930	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CIT39_RS26935	COG0791	NLP P60 protein
CIT39_RS26940	COG4172	Belongs to the ABC transporter superfamily
CIT39_RS26945	COG4239	(ABC) transporter, permease
CIT39_RS26950	COG4174	ABC transporter (Permease)
CIT39_RS26955	COG4166	transmembrane transport
CIT39_RS26960	COG4166	transmembrane transport
CIT39_RS26965	COG3474	cytochrome
CIT39_RS26970	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CIT39_RS26975	COG0077	Prephenate dehydratase
CIT39_RS26975	COG1605	Chorismate mutase
CIT39_RS26980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CIT39_RS27020	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CIT39_RS27025	COG2852	Protein conserved in bacteria
CIT39_RS27030	COG1696	Membrane protein involved in D-alanine export
CIT39_RS27050	COG1960	acyl-CoA dehydrogenase activity
CIT39_RS27055	COG0183	Belongs to the thiolase family
CIT39_RS27060	COG0318	PFAM AMP-dependent synthetase and ligase
CIT39_RS27085	COG0559	Belongs to the binding-protein-dependent transport system permease family
CIT39_RS27145	COG0583	DNA-binding transcription factor activity
CIT39_RS27170	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CIT39_RS27190	COG1024	Enoyl-CoA hydratase
CIT39_RS27195	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS27195	COG0300	oxidoreductase activity
CIT39_RS27195	COG3321	synthase
CIT39_RS27195	COG0318	PFAM AMP-dependent synthetase and ligase
CIT39_RS27195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CIT39_RS27255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CIT39_RS27270	COG2378	regulation of single-species biofilm formation
CIT39_RS27290	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CIT39_RS27295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CIT39_RS27305	COG0604	alcohol dehydrogenase
CIT39_RS27320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CIT39_RS27325	COG0842	Transport permease protein
CIT39_RS27325	COG1129	ABC transporter
CIT39_RS27330	COG0842	Transport permease protein
CIT39_RS27355	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CIT39_RS27375	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS27385	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS27400	COG0179	Fumarylacetoacetate (FAA) hydrolase
CIT39_RS27415	COG2267	carboxylic ester hydrolase activity
CIT39_RS27425	COG0154	amidase activity
CIT39_RS27435	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CIT39_RS27440	COG1960	acyl-CoA dehydrogenase activity
CIT39_RS27445	COG4221	oxidoreductase activity
CIT39_RS27450	COG1024	Enoyl-CoA hydratase
CIT39_RS27465	COG0583	DNA-binding transcription factor activity
CIT39_RS27490	COG1058	Belongs to the CinA family
CIT39_RS27490	COG1546	Belongs to the CinA family
CIT39_RS27500	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CIT39_RS27505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CIT39_RS27510	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CIT39_RS27520	COG0444	Belongs to the ABC transporter superfamily
CIT39_RS27525	COG0154	amidase activity
CIT39_RS27535	COG4608	Belongs to the ABC transporter superfamily
CIT39_RS27540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CIT39_RS27555	COG0747	negative chemotaxis
CIT39_RS27560	COG0747	negative chemotaxis
CIT39_RS27650	COG2309	aminopeptidase activity
CIT39_RS27655	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CIT39_RS27680	COG2070	2-Nitropropane dioxygenase
CIT39_RS27685	COG0318	PFAM AMP-dependent synthetase and ligase
CIT39_RS27695	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CIT39_RS27710	COG1027	Aspartate ammonia-lyase
CIT39_RS27720	COG1238	metal cluster binding
CIT39_RS27725	COG0140	phosphoribosyl-ATP diphosphatase activity
CIT39_RS27740	COG1132	(ABC) transporter
CIT39_RS27745	COG1686	Belongs to the peptidase S11 family
CIT39_RS27750	COG0318	PFAM AMP-dependent synthetase and ligase
CIT39_RS27760	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CIT39_RS27760	COG0678	peroxiredoxin activity
CIT39_RS27770	COG0328	RNA-DNA hybrid ribonuclease activity
CIT39_RS27775	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CIT39_RS27780	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CIT39_RS27790	COG3047	cAMP biosynthetic process
CIT39_RS27825	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS27840	COG2358	TRAP transporter, solute receptor (TAXI family
CIT39_RS27870	COG0667	Aldo Keto reductase
CIT39_RS27885	COG4716	Myosin-crossreactive antigen
CIT39_RS27890	COG1022	Amp-dependent synthetase and ligase
CIT39_RS27895	COG1335	isochorismatase
CIT39_RS27930	COG1595	DNA-templated transcription, initiation
CIT39_RS27935	COG3806	Anti-sigma factor
CIT39_RS27940	COG1595	DNA-templated transcription, initiation
CIT39_RS27970	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CIT39_RS27975	COG0583	DNA-binding transcription factor activity
CIT39_RS27985	COG1116	anion transmembrane transporter activity
CIT39_RS27990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CIT39_RS27995	COG0243	molybdopterin cofactor binding
CIT39_RS28005	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CIT39_RS28010	COG0424	maF-like protein
CIT39_RS28020	COG5328	Belongs to the UPF0262 family
CIT39_RS28025	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CIT39_RS28055	COG3634	alkyl hydroperoxide reductase activity
CIT39_RS28075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CIT39_RS28090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CIT39_RS28105	COG3971	2-oxopent-4-enoate hydratase activity
CIT39_RS28110	COG0179	Fumarylacetoacetate (FAA) hydrolase
CIT39_RS28115	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CIT39_RS28120	COG3181	Tripartite tricarboxylate transporter family receptor
CIT39_RS28135	COG2267	carboxylic ester hydrolase activity
CIT39_RS28140	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS28155	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CIT39_RS28160	COG3454	Phosphonate metabolism
CIT39_RS28165	COG4778	phosphonate C-P lyase system protein PhnL
CIT39_RS28170	COG4107	phosphonate C-P lyase system protein PhnK
CIT39_RS28175	COG3627	carbon phosphorus lyase activity
CIT39_RS28180	COG3626	phosphonate metabolism
CIT39_RS28185	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CIT39_RS28190	COG3624	Phosphonate C-P lyase system protein PhnG
CIT39_RS28195	COG2188	Transcriptional regulator
CIT39_RS28205	COG3639	organic phosphonate transmembrane transporter activity
CIT39_RS28210	COG3639	organic phosphonate transmembrane transporter activity
CIT39_RS28220	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CIT39_RS28230	COG3454	Phosphonate metabolism
CIT39_RS28235	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CIT39_RS28250	COG1024	Enoyl-CoA hydratase
CIT39_RS28260	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CIT39_RS28270	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CIT39_RS28290	COG4774	siderophore transport
CIT39_RS28295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CIT39_RS28300	COG0277	FAD linked oxidase domain protein
CIT39_RS28305	COG1802	Transcriptional regulator
CIT39_RS28325	COG1032	radical SAM domain protein
CIT39_RS28335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CIT39_RS28340	COG1116	anion transmembrane transporter activity
CIT39_RS28360	COG1959	2 iron, 2 sulfur cluster binding
CIT39_RS28385	COG0583	DNA-binding transcription factor activity
CIT39_RS28390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CIT39_RS28455	COG0730	response to heat
CIT39_RS28460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CIT39_RS28465	COG0640	Transcriptional regulator
CIT39_RS28485	COG4232	protein-disulfide reductase activity
CIT39_RS28495	COG1388	LysM domain
CIT39_RS28495	COG1376	ErfK ybiS ycfS ynhG family protein
CIT39_RS28520	COG2391	methyltransferase activity
CIT39_RS28525	COG1376	ErfK ybiS ycfS ynhG family protein
CIT39_RS28525	COG1388	LysM domain
CIT39_RS28535	COG2264	protein methyltransferase activity
CIT39_RS28555	COG0720	synthase
CIT39_RS28565	COG3852	Histidine kinase
CIT39_RS28570	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CIT39_RS28580	COG0706	membrane insertase activity
CIT39_RS28585	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CIT39_RS28595	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CIT39_RS28610	COG2171	N-acyltransferase activity
CIT39_RS28620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CIT39_RS28625	COG0101	tRNA pseudouridine synthase activity
CIT39_RS28630	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CIT39_RS28635	COG0242	peptide deformylase activity
CIT39_RS28650	COG2223	nitrite transmembrane transporter activity
CIT39_RS28660	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CIT39_RS28665	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CIT39_RS28670	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CIT39_RS28685	COG0765	amino acid transport
CIT39_RS28715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CIT39_RS28720	COG1522	sequence-specific DNA binding
CIT39_RS28725	COG2205	protein histidine kinase activity
CIT39_RS28750	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CIT39_RS28755	COG3577	Aspartyl protease
CIT39_RS28760	COG1643	Atp-dependent helicase
CIT39_RS28765	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CIT39_RS28775	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CIT39_RS28775	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CIT39_RS28780	COG1280	lysine exporter protein (LysE YggA)
CIT39_RS28785	COG0625	glutathione transferase activity
CIT39_RS28790	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CIT39_RS28810	COG1201	RNA secondary structure unwinding
CIT39_RS28820	COG0251	oxidation-reduction process
CIT39_RS28840	COG1999	signal sequence binding
CIT39_RS28850	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
CIT39_RS28870	COG0167	dihydroorotate dehydrogenase activity
CIT39_RS28880	COG1234	tRNA 3'-trailer cleavage
CIT39_RS28890	COG1793	dna ligase
CIT39_RS28925	COG1172	Belongs to the binding-protein-dependent transport system permease family
CIT39_RS28930	COG1129	ABC transporter
CIT39_RS28935	COG2115	Belongs to the xylose isomerase family
CIT39_RS28940	COG1070	Carbohydrate kinase
CIT39_RS28945	COG1609	Transcriptional regulator
CIT39_RS28965	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CIT39_RS29005	COG4191	Histidine kinase
CIT39_RS29010	COG0717	Belongs to the dCTP deaminase family
CIT39_RS29035	COG2967	ApaG domain
CIT39_RS29050	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CIT39_RS29055	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CIT39_RS29065	COG0745	RESPONSE REGULATOR receiver
CIT39_RS29070	COG0704	Plays a role in the regulation of phosphate uptake
CIT39_RS29075	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CIT39_RS29080	COG0581	inorganic phosphate transmembrane transporter activity
CIT39_RS29085	COG0573	inorganic phosphate transmembrane transporter activity
CIT39_RS29090	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CIT39_RS29095	COG5002	protein histidine kinase activity
CIT39_RS29155	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CIT39_RS29160	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CIT39_RS29185	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CIT39_RS29185	COG4651	solute:proton antiporter activity
CIT39_RS29190	COG1414	Transcriptional regulator
CIT39_RS29195	COG4638	Rieske (2fe-2S)
CIT39_RS29205	COG0477	Major facilitator Superfamily
CIT39_RS29245	COG3916	Acyl-homoserine-lactone synthase
CIT39_RS29250	COG2197	response regulator
CIT39_RS29265	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CIT39_RS29270	COG4251	negative regulation of phosphorylation
CIT39_RS29275	COG3920	Histidine kinase
CIT39_RS29285	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CIT39_RS29300	COG1252	NADH dehydrogenase
CIT39_RS29310	COG2124	cytochrome p450
CIT39_RS29320	COG0318	PFAM AMP-dependent synthetase and ligase
CIT39_RS29335	COG1802	Transcriptional regulator
CIT39_RS29355	COG4172	Belongs to the ABC transporter superfamily
CIT39_RS29360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CIT39_RS29365	COG0601	transmembrane transport
CIT39_RS29370	COG0747	negative chemotaxis
CIT39_RS29385	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CIT39_RS29390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CIT39_RS29390	COG4191	Histidine kinase
CIT39_RS29395	COG0784	Response regulator, receiver
CIT39_RS29395	COG3437	response regulator, receiver
CIT39_RS29405	COG1595	DNA-templated transcription, initiation
CIT39_RS29420	COG1271	oxidase subunit
CIT39_RS29425	COG1294	oxidase, subunit
CIT39_RS29450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CIT39_RS29455	COG1960	acyl-CoA dehydrogenase activity
CIT39_RS29460	COG1960	acyl-CoA dehydrogenase activity
CIT39_RS29470	COG2514	catechol 2,3-dioxygenase activity
CIT39_RS29480	COG2814	Major facilitator Superfamily
CIT39_RS29485	COG1505	serine-type exopeptidase activity
CIT39_RS29510	COG3258	Cytochrome c
CIT39_RS29520	COG0737	Belongs to the 5'-nucleotidase family
CIT39_RS29540	COG2271	Major facilitator Superfamily
CIT39_RS29550	COG2271	Major facilitator Superfamily
CIT39_RS29570	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CIT39_RS29575	COG0683	leucine binding
CIT39_RS29585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CIT39_RS29605	COG0601	transmembrane transport
CIT39_RS29610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CIT39_RS29615	COG0444	Belongs to the ABC transporter superfamily
CIT39_RS29620	COG4608	Belongs to the ABC transporter superfamily
CIT39_RS29635	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CIT39_RS29640	COG3246	L-lysine catabolic process to acetate
CIT39_RS29655	COG1960	acyl-CoA dehydrogenase activity
CIT39_RS29660	COG1960	acyl-CoA dehydrogenase activity
CIT39_RS29705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CIT39_RS29725	COG1129	ABC transporter
CIT39_RS29745	COG5002	protein histidine kinase activity
CIT39_RS29745	COG0784	Response regulator, receiver
CIT39_RS29745	COG2198	Histidine kinase
CIT39_RS29750	COG0745	RESPONSE REGULATOR receiver
CIT39_RS29755	COG2072	flavoprotein involved in K transport
CIT39_RS29770	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CIT39_RS29775	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CIT39_RS29780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CIT39_RS29790	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CIT39_RS29800	COG5001	Diguanylate cyclase
CIT39_RS29820	COG5001	Diguanylate cyclase
CIT39_RS29820	COG3300	MHYT domain
CIT39_RS29835	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CIT39_RS29840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CIT39_RS29845	COG0142	geranyltranstransferase activity
CIT39_RS29875	COG0025	NhaP-type Na H and K H
CIT39_RS29895	COG2175	clavaminate synthase activity
CIT39_RS29900	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CIT39_RS29910	COG0735	belongs to the Fur family
CIT39_RS29920	COG1566	PFAM secretion protein HlyD family protein
CIT39_RS29925	COG2814	Major facilitator Superfamily
CIT39_RS29935	COG0840	transmembrane signaling receptor activity
CIT39_RS29940	COG0840	transmembrane signaling receptor activity
CIT39_RS29945	COG3485	protocatechuate 3,4-dioxygenase
CIT39_RS29950	COG3485	protocatechuate 3,4-dioxygenase
CIT39_RS29955	COG0183	Belongs to the thiolase family
CIT39_RS29960	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CIT39_RS29980	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CIT39_RS30010	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CIT39_RS30030	COG1131	(ABC) transporter
CIT39_RS30040	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CIT39_RS30055	COG0366	Alpha amylase catalytic
CIT39_RS30060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CIT39_RS30065	COG1733	regulation of RNA biosynthetic process
CIT39_RS30095	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS30105	COG5001	Diguanylate cyclase
CIT39_RS30110	COG3829	transcription factor binding
CIT39_RS30110	COG3290	protein histidine kinase activity
CIT39_RS30140	COG5001	Diguanylate cyclase
CIT39_RS30145	COG2199	diguanylate cyclase activity
CIT39_RS30160	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CIT39_RS30210	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CIT39_RS30225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CIT39_RS30280	COG0596	Alpha beta hydrolase
CIT39_RS30290	COG0412	Dienelactone hydrolase
CIT39_RS30310	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CIT39_RS30320	COG0268	Binds directly to 16S ribosomal RNA
CIT39_RS30330	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CIT39_RS30340	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CIT39_RS30365	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CIT39_RS30375	COG0534	Mate efflux family protein
CIT39_RS30410	COG1741	Belongs to the pirin family
CIT39_RS30415	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CIT39_RS30440	COG0318	PFAM AMP-dependent synthetase and ligase
CIT39_RS30445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CIT39_RS30455	COG0180	Tryptophanyl-tRNA synthetase
CIT39_RS30485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CIT39_RS30490	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CIT39_RS30495	COG1702	phosphate starvation-inducible protein PhoH
CIT39_RS30500	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CIT39_RS30505	COG1253	flavin adenine dinucleotide binding
CIT39_RS30510	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CIT39_RS30515	COG1396	sequence-specific DNA binding
CIT39_RS30525	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CIT39_RS30535	COG0779	Required for maturation of 30S ribosomal subunits
CIT39_RS30550	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CIT39_RS30555	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CIT39_RS30560	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CIT39_RS30565	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CIT39_RS30570	COG1185	polyribonucleotide nucleotidyltransferase activity
CIT39_RS30580	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CIT39_RS30600	COG0625	glutathione transferase activity
CIT39_RS30605	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CIT39_RS30615	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CIT39_RS30640	COG0667	Aldo Keto reductase
CIT39_RS30645	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CIT39_RS30670	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CIT39_RS30675	COG2226	methyltransferase
CIT39_RS30680	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CIT39_RS30685	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CIT39_RS30690	COG0756	dUTP diphosphatase activity
CIT39_RS30695	COG2205	protein histidine kinase activity
CIT39_RS30700	COG3178	'Phosphotransferase
CIT39_RS30710	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CIT39_RS30730	COG1793	dna ligase
CIT39_RS30740	COG0285	dihydrofolate synthase activity
CIT39_RS30745	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CIT39_RS30750	COG0159	tryptophan synthase activity
CIT39_RS30755	COG0133	tryptophan synthase activity
CIT39_RS30760	COG0135	phosphoribosylanthranilate isomerase activity
CIT39_RS30770	COG0776	regulation of translation
CIT39_RS30775	COG0616	signal peptide processing
CIT39_RS30780	COG0539	negative regulation of cytoplasmic translation
CIT39_RS30785	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CIT39_RS30790	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CIT39_RS30810	COG1846	Transcriptional regulator
CIT39_RS30815	COG1764	response to oxidative stress
CIT39_RS30835	COG0395	ABC-type sugar transport system, permease component
CIT39_RS30840	COG3842	ATPase activity
CIT39_RS30845	COG0071	Belongs to the small heat shock protein (HSP20) family
CIT39_RS30855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CIT39_RS30860	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CIT39_RS30865	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CIT39_RS30870	COG1137	ATPase activity
CIT39_RS30875	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CIT39_RS30890	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CIT39_RS30895	COG2814	Major facilitator Superfamily
CIT39_RS30920	COG0277	FAD linked oxidase domain protein
CIT39_RS30925	COG1968	undecaprenyl-diphosphatase activity
CIT39_RS30935	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CIT39_RS30955	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CIT39_RS30965	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CIT39_RS30970	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CIT39_RS30975	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CIT39_RS30980	COG0072	phenylalanine-tRNA ligase activity
CIT39_RS30980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CIT39_RS31000	COG1937	Protein conserved in bacteria
CIT39_RS31010	COG0864	Transcriptional regulator
CIT39_RS31030	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CIT39_RS31040	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CIT39_RS31045	COG0588	phosphoglycerate mutase activity
CIT39_RS31050	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CIT39_RS31060	COG0284	orotidine-5'-phosphate decarboxylase activity
CIT39_RS31065	COG0431	NADPH-dependent FMN reductase
CIT39_RS31070	COG3963	phosphatidate phosphatase activity
CIT39_RS31075	COG0484	heat shock protein binding
CIT39_RS31085	COG0443	Heat shock 70 kDa protein
CIT39_RS31095	COG1335	isochorismatase
CIT39_RS31100	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CIT39_RS31105	COG1420	regulation of RNA biosynthetic process
CIT39_RS31110	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CIT39_RS31115	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CIT39_RS31120	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CIT39_RS31135	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CIT39_RS31140	COG0792	nuclease activity
CIT39_RS31145	COG0189	ligase activity
CIT39_RS31155	COG4964	Belongs to the GSP D family
CIT39_RS31190	COG0784	Response regulator, receiver
CIT39_RS31190	COG5002	protein histidine kinase activity
CIT39_RS31190	COG2205	protein histidine kinase activity
CIT39_RS31200	COG0628	permease
CIT39_RS31210	COG1072	(Pantothenic acid kinase))
CIT39_RS31215	COG0140	phosphoribosyl-ATP diphosphatase activity
CIT39_RS31220	COG0107	imidazoleglycerol-phosphate synthase activity
CIT39_RS31225	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CIT39_RS31230	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CIT39_RS31240	COG0131	Imidazoleglycerol-phosphate dehydratase
CIT39_RS31245	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CIT39_RS31260	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CIT39_RS31275	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CIT39_RS31285	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CIT39_RS31290	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CIT39_RS31295	COG0237	dephospho-CoA kinase activity
CIT39_RS31300	COG0424	maF-like protein
CIT39_RS31305	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CIT39_RS31315	COG1981	membrane
CIT39_RS31320	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CIT39_RS31325	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CIT39_RS31330	COG0445	tRNA wobble uridine modification
CIT39_RS31335	COG0357	Ribosomal RNA small subunit methyltransferase G
CIT39_RS31360	COG0495	leucyl-tRNA aminoacylation
CIT39_RS31365	COG3706	GGDEF domain
CIT39_RS31370	COG2203	Gaf domain
CIT39_RS31370	COG5001	Diguanylate cyclase
CIT39_RS31370	COG4251	negative regulation of phosphorylation
CIT39_RS31370	COG3706	GGDEF domain
CIT39_RS31375	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CIT39_RS31390	COG0745	RESPONSE REGULATOR receiver
CIT39_RS31405	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CIT39_RS31410	COG1674	ftsk spoiiie
CIT39_RS31415	COG0436	Aminotransferase
CIT39_RS31425	COG0004	ammonium transporteR
CIT39_RS31430	COG0347	Belongs to the P(II) protein family
CIT39_RS31435	COG0004	ammonium transporteR
CIT39_RS31440	COG0347	Belongs to the P(II) protein family
CIT39_RS31455	COG1946	Acyl-CoA thioesterase
CIT39_RS31460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CIT39_RS31465	COG2835	tetraacyldisaccharide 4'-kinase activity
CIT39_RS31490	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CIT39_RS31495	COG3118	belongs to the thioredoxin family
CIT39_RS31505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CIT39_RS31525	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CIT39_RS31535	COG0534	Mate efflux family protein
CIT39_RS31550	COG2814	Major facilitator Superfamily
CIT39_RS31555	COG0405	Gamma-glutamyltransferase
CIT39_RS31565	COG0138	bifunctional purine biosynthesis protein purh
CIT39_RS31590	COG1376	ErfK ybiS ycfS ynhG family protein
CIT39_RS31595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CIT39_RS31610	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CIT39_RS31615	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CIT39_RS31650	COG0726	polysaccharide deacetylase
CIT39_RS31665	COG2814	Major facilitator Superfamily
CIT39_RS31690	COG4221	oxidoreductase activity
CIT39_RS31695	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CIT39_RS31700	COG1024	Enoyl-CoA hydratase
CIT39_RS31720	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CIT39_RS31725	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CIT39_RS31730	COG1247	-acetyltransferase
CIT39_RS31740	COG3011	Protein conserved in bacteria
CIT39_RS31750	COG1217	gtp-binding protein TYPA
CIT39_RS31775	COG0784	Response regulator, receiver
CIT39_RS31790	COG2154	pterin-4-alpha-carbinolamine dehydratase
CIT39_RS31805	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS31815	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CIT39_RS31825	COG0671	phosphoesterase, PA-phosphatase related
CIT39_RS31830	COG0137	argininosuccinate synthase activity
CIT39_RS31835	COG1785	Belongs to the alkaline phosphatase family
CIT39_RS31900	COG0730	response to heat
CIT39_RS31910	COG0318	PFAM AMP-dependent synthetase and ligase
CIT39_RS31915	COG4221	oxidoreductase activity
CIT39_RS31920	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CIT39_RS31925	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
CIT39_RS31930	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CIT39_RS31940	COG0473	3-isopropylmalate dehydrogenase activity
CIT39_RS31960	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CIT39_RS31965	COG0288	reversible hydration of carbon dioxide
CIT39_RS31970	COG2301	Belongs to the HpcH HpaI aldolase family
CIT39_RS31980	COG4977	sequence-specific DNA binding
CIT39_RS31990	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS31995	COG2207	Transcriptional regulator
CIT39_RS32015	COG0066	3-isopropylmalate dehydratase activity
CIT39_RS32045	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CIT39_RS32050	COG0335	large ribosomal subunit rRNA binding
CIT39_RS32055	COG0336	Belongs to the RNA methyltransferase TrmD family
CIT39_RS32060	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CIT39_RS32065	COG0228	four-way junction DNA binding
CIT39_RS32070	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CIT39_RS32090	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CIT39_RS32095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CIT39_RS32105	COG0564	pseudouridine synthase activity
CIT39_RS32110	COG0552	protein localization to endoplasmic reticulum
CIT39_RS32115	COG2917	probably involved in intracellular septation
CIT39_RS32120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CIT39_RS32130	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CIT39_RS32135	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CIT39_RS32140	COG4133	protoheme IX ABC transporter activity
CIT39_RS32145	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CIT39_RS32165	COG0670	Belongs to the BI1 family
CIT39_RS32170	COG1136	(ABC) transporter
CIT39_RS32170	COG0577	efflux transmembrane transporter activity
CIT39_RS32175	COG1136	(ABC) transporter
CIT39_RS32180	COG2755	lipolytic protein G-D-S-L family
CIT39_RS32185	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CIT39_RS32190	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CIT39_RS32195	COG0039	L-malate dehydrogenase activity
CIT39_RS32200	COG0045	succinate-CoA ligase (ADP-forming) activity
CIT39_RS32210	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CIT39_RS32220	COG0508	dehydrogenase complex catalyzes the overall conversion of
CIT39_RS32225	COG1028	Short-chain dehydrogenase reductase Sdr
CIT39_RS32230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CIT39_RS32245	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CIT39_RS32255	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CIT39_RS32260	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CIT39_RS32265	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CIT39_RS32270	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CIT39_RS32275	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CIT39_RS32280	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CIT39_RS32290	COG0494	nUDIX hydrolase
CIT39_RS32295	COG1051	belongs to the nudix hydrolase family
CIT39_RS32305	COG0793	Belongs to the peptidase S41A family
CIT39_RS32315	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CIT39_RS32320	COG0799	negative regulation of ribosome biogenesis
CIT39_RS32325	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CIT39_RS32330	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CIT39_RS32335	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CIT39_RS32345	COG4106	trans-aconitate 2-methyltransferase activity
CIT39_RS32365	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CIT39_RS32380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CIT39_RS32385	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CIT39_RS32390	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CIT39_RS32405	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CIT39_RS32420	COG0697	spore germination
CIT39_RS32425	COG3706	GGDEF domain
CIT39_RS32425	COG5001	Diguanylate cyclase
CIT39_RS32425	COG2203	Gaf domain
CIT39_RS32425	COG4251	negative regulation of phosphorylation
CIT39_RS32465	COG0643	Histidine kinase
CIT39_RS32465	COG2198	Histidine kinase
CIT39_RS32465	COG0784	Response regulator, receiver
CIT39_RS32470	COG0835	chemotaxis
CIT39_RS32475	COG0745	RESPONSE REGULATOR receiver
CIT39_RS32490	COG2201	protein-glutamate methylesterase activity
CIT39_RS32500	COG4566	intracellular signal transduction
CIT39_RS32505	COG4191	Histidine kinase
CIT39_RS32505	COG0784	Response regulator, receiver
CIT39_RS32510	COG2204	response regulator
CIT39_RS32520	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CIT39_RS32535	COG1696	Membrane protein involved in D-alanine export
CIT39_RS32545	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CIT39_RS32575	COG2706	6-phosphogluconolactonase activity
CIT39_RS32585	COG5001	Diguanylate cyclase
CIT39_RS32605	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CIT39_RS32610	COG0179	Fumarylacetoacetate (FAA) hydrolase
CIT39_RS32620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CIT39_RS32640	COG1802	Transcriptional regulator
CIT39_RS32660	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CIT39_RS32695	COG1846	Transcriptional regulator
CIT39_RS32700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CIT39_RS32715	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CIT39_RS32725	COG3813	Protein conserved in bacteria
CIT39_RS32730	COG1522	sequence-specific DNA binding
CIT39_RS32740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CIT39_RS32770	COG0477	Major facilitator Superfamily
CIT39_RS32775	COG1877	trehalose-phosphatase activity
CIT39_RS32780	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CIT39_RS32795	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CIT39_RS32805	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CIT39_RS32820	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CIT39_RS32855	COG1111	helicase
CIT39_RS32855	COG1205	dead DEAH box helicase
CIT39_RS32930	COG1672	PFAM Archaeal ATPase
CIT39_RS32930	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CIT39_RS32945	COG0583	DNA-binding transcription factor activity
CIT39_RS32950	COG2814	Major facilitator Superfamily
CIT39_RS32955	COG0154	amidase activity
CIT39_RS32960	COG2873	o-acetylhomoserine
CIT39_RS32975	COG0514	ATP-dependent DNA helicase (RecQ)
CIT39_RS32980	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CIT39_RS32985	COG1522	sequence-specific DNA binding
CIT39_RS33030	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CIT39_RS33045	COG0697	spore germination
CIT39_RS33055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CIT39_RS33070	COG2890	protein-(glutamine-N5) methyltransferase activity
CIT39_RS33110	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CIT39_RS33115	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CIT39_RS33120	COG0527	aspartate kinase activity
CIT39_RS33130	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CIT39_RS33145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CIT39_RS33155	COG1040	competence protein
CIT39_RS33175	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CIT39_RS33180	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CIT39_RS33185	COG0653	protein targeting
CIT39_RS33220	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CIT39_RS33240	COG3034	peptidoglycan biosynthetic process
CIT39_RS33245	COG0825	malonyl-CoA metabolic process
CIT39_RS33250	COG4974	Belongs to the 'phage' integrase family
CIT39_RS33260	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CIT39_RS33265	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CIT39_RS33270	COG1253	flavin adenine dinucleotide binding
CIT39_RS33290	COG0372	Belongs to the citrate synthase family
CIT39_RS33295	COG0372	Belongs to the citrate synthase family
CIT39_RS33315	COG0586	Pfam SNARE associated Golgi protein
CIT39_RS33335	COG1902	pentaerythritol trinitrate reductase activity
CIT39_RS33375	COG1204	response to ionizing radiation
CIT39_RS33380	COG0227	Belongs to the bacterial ribosomal protein bL28 family