locus-tag	class	description
AWC36_RS00060	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AWC36_RS00080	COG5510	response to toxic substance
AWC36_RS00085	COG0583	DNA-binding transcription factor activity
AWC36_RS00110	COG3711	transcriptional antiterminator
AWC36_RS00115	COG1263	PTS System
AWC36_RS00115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWC36_RS00115	COG2190	(PTS) system
AWC36_RS00120	COG2723	6-phospho-beta-galactosidase activity
AWC36_RS00125	COG2723	6-phospho-beta-galactosidase activity
AWC36_RS00130	COG0204	Acyl-transferase
AWC36_RS00130	COG0318	PFAM AMP-dependent synthetase and ligase
AWC36_RS00135	COG0477	Major facilitator Superfamily
AWC36_RS00140	COG2153	protein acetylation
AWC36_RS00155	COG0318	PFAM AMP-dependent synthetase and ligase
AWC36_RS00165	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AWC36_RS00170	COG0644	oxidoreductase
AWC36_RS00175	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AWC36_RS00180	COG2086	electron transfer activity
AWC36_RS00185	COG1960	acyl-CoA dehydrogenase activity
AWC36_RS00190	COG1960	acyl-CoA dehydrogenase activity
AWC36_RS00195	COG2271	Major facilitator Superfamily
AWC36_RS00210	COG5510	response to toxic substance
AWC36_RS00220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AWC36_RS00225	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AWC36_RS00230	COG1872	DUF167
AWC36_RS00235	COG0762	integral membrane protein
AWC36_RS00240	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AWC36_RS00245	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AWC36_RS00250	COG2805	Type II/IV secretion system protein
AWC36_RS00260	COG1263	PTS System
AWC36_RS00260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWC36_RS00265	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AWC36_RS00280	COG0504	CTP synthase activity
AWC36_RS00340	COG1959	2 iron, 2 sulfur cluster binding
AWC36_RS00345	COG0557	exoribonuclease II activity
AWC36_RS00350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AWC36_RS00355	COG3766	membrane
AWC36_RS00370	COG1073	alpha beta
AWC36_RS00375	COG1414	Transcriptional regulator
AWC36_RS00380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AWC36_RS00385	COG2721	sulfolactate sulfo-lyase activity
AWC36_RS00390	COG2271	Major facilitator Superfamily
AWC36_RS00395	COG0360	Binds together with S18 to 16S ribosomal RNA
AWC36_RS00400	COG2965	DNA replication, synthesis of RNA primer
AWC36_RS00405	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AWC36_RS00410	COG0359	binds to the 23S rRNA
AWC36_RS00415	COG3061	Opacity-associated protein A
AWC36_RS00420	COG0545	Peptidyl-prolyl cis-trans isomerase
AWC36_RS00425	COG3961	Belongs to the TPP enzyme family
AWC36_RS00430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AWC36_RS00450	COG0410	ABC transporter
AWC36_RS00455	COG1137	ATPase activity
AWC36_RS00460	COG4177	L-phenylalanine transmembrane transporter activity
AWC36_RS00480	COG0737	Belongs to the 5'-nucleotidase family
AWC36_RS00485	COG1218	3'(2'),5'-bisphosphate nucleotidase
AWC36_RS00495	COG1253	flavin adenine dinucleotide binding
AWC36_RS00500	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AWC36_RS00505	COG0729	surface antigen
AWC36_RS00515	COG2105	PFAM AIG2 family protein
AWC36_RS00525	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AWC36_RS00530	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AWC36_RS00535	COG1968	undecaprenyl-diphosphatase activity
AWC36_RS00540	COG0617	tRNA 3'-terminal CCA addition
AWC36_RS00545	COG4991	sh3 domain protein
AWC36_RS00550	COG3025	triphosphatase activity
AWC36_RS00555	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AWC36_RS00560	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AWC36_RS00560	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AWC36_RS00565	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AWC36_RS00570	COG3530	Putative quorum-sensing-regulated virulence factor
AWC36_RS00585	COG0840	transmembrane signaling receptor activity
AWC36_RS00595	COG2721	sulfolactate sulfo-lyase activity
AWC36_RS00600	COG2271	Major facilitator Superfamily
AWC36_RS00610	COG2084	Dehydrogenase
AWC36_RS00615	COG1929	Belongs to the glycerate kinase type-1 family
AWC36_RS00620	COG2205	protein histidine kinase activity
AWC36_RS00620	COG3437	response regulator, receiver
AWC36_RS00620	COG3850	Histidine kinase
AWC36_RS00620	COG4999	Histidine kinase
AWC36_RS00625	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AWC36_RS00630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AWC36_RS00635	COG3956	TIGRFAM MazG family protein
AWC36_RS00645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWC36_RS00655	COG1012	belongs to the aldehyde dehydrogenase family
AWC36_RS00660	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AWC36_RS00665	COG3842	ATPase activity
AWC36_RS00670	COG1176	ABC-type spermidine putrescine transport system, permease component I
AWC36_RS00675	COG1177	transmembrane transport
AWC36_RS00680	COG0504	CTP synthase activity
AWC36_RS00690	COG3385	transposase activity
AWC36_RS00705	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AWC36_RS00715	COG0602	queuosine metabolic process
AWC36_RS00720	COG0720	synthase
AWC36_RS00725	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AWC36_RS00730	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AWC36_RS00735	COG0175	sulfate reduction
AWC36_RS00740	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AWC36_RS00740	COG1648	precorrin-2 dehydrogenase activity
AWC36_RS00745	COG0175	sulfate reduction
AWC36_RS00750	COG2895	sulfate adenylyltransferase (ATP) activity
AWC36_RS00755	COG0529	Catalyzes the synthesis of activated sulfate
AWC36_RS00765	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AWC36_RS00770	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AWC36_RS00775	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AWC36_RS00780	COG0585	pseudouridine synthase activity
AWC36_RS00785	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AWC36_RS00790	COG1388	LysM domain
AWC36_RS00790	COG4942	peptidase
AWC36_RS00800	COG0442	prolyl-tRNA aminoacylation
AWC36_RS00805	COG1720	tRNA m6t6A37 methyltransferase activity
AWC36_RS00815	COG1464	Belongs to the NlpA lipoprotein family
AWC36_RS00820	COG2011	ABC-type metal ion transport system permease component
AWC36_RS00825	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AWC36_RS00830	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AWC36_RS00865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AWC36_RS00870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWC36_RS00870	COG1042	CoA-binding domain protein
AWC36_RS00870	COG0045	succinate-CoA ligase (ADP-forming) activity
AWC36_RS00875	COG3148	PFAM DTW domain containing protein
AWC36_RS00880	COG3118	belongs to the thioredoxin family
AWC36_RS00885	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AWC36_RS00895	COG2814	Major facilitator Superfamily
AWC36_RS00900	COG1566	PFAM secretion protein HlyD family protein
AWC36_RS00905	COG1846	Transcriptional regulator
AWC36_RS00910	COG2113	Glycine betaine
AWC36_RS00915	COG4176	ABC-type proline glycine betaine transport system permease component
AWC36_RS00920	COG4175	Glycine betaine
AWC36_RS00940	COG0738	Major facilitator superfamily
AWC36_RS00945	COG0583	DNA-binding transcription factor activity
AWC36_RS00950	COG2271	Major facilitator Superfamily
AWC36_RS00965	COG4670	ketone body catabolic process
AWC36_RS00970	COG1960	acyl-CoA dehydrogenase activity
AWC36_RS00975	COG2207	Transcriptional regulator
AWC36_RS00975	COG1917	Cupin 2, conserved barrel domain protein
AWC36_RS00980	COG2086	electron transfer activity
AWC36_RS00985	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AWC36_RS00990	COG0644	oxidoreductase
AWC36_RS00995	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AWC36_RS01000	COG0318	PFAM AMP-dependent synthetase and ligase
AWC36_RS01010	COG0436	Aminotransferase
AWC36_RS01015	COG0235	Class ii aldolase
AWC36_RS01020	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AWC36_RS01025	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AWC36_RS01030	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AWC36_RS01035	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AWC36_RS01045	COG0488	(ABC) transporter
AWC36_RS01050	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AWC36_RS01055	COG0121	glutamine amidotransferase
AWC36_RS01060	COG3034	peptidoglycan biosynthetic process
AWC36_RS01065	COG2226	methyltransferase
AWC36_RS01070	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AWC36_RS01075	COG2195	Cleaves the N-terminal amino acid of tripeptides
AWC36_RS01085	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AWC36_RS01090	COG1073	alpha beta
AWC36_RS01100	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AWC36_RS01105	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AWC36_RS01115	COG0582	viral genome integration into host DNA
AWC36_RS01155	COG0640	Transcriptional regulator
AWC36_RS01240	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AWC36_RS01275	COG2916	Histone family protein nucleoid-structuring protein H-NS
AWC36_RS01285	COG2165	general secretion pathway protein
AWC36_RS01305	COG2161	toxin-antitoxin pair type II binding
AWC36_RS01365	COG1546	Belongs to the CinA family
AWC36_RS01370	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AWC36_RS01375	COG2137	regulation of response to DNA damage stimulus
AWC36_RS01380	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AWC36_RS01385	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AWC36_RS01415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AWC36_RS01420	COG1238	metal cluster binding
AWC36_RS01425	COG2918	glutathione biosynthetic process
AWC36_RS01430	COG1854	S-ribosylhomocysteine lyase activity
AWC36_RS01435	COG4137	Cytochrome C assembly protein
AWC36_RS01440	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AWC36_RS01445	COG0228	four-way junction DNA binding
AWC36_RS01450	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AWC36_RS01455	COG0336	Belongs to the RNA methyltransferase TrmD family
AWC36_RS01460	COG0335	large ribosomal subunit rRNA binding
AWC36_RS01470	COG3279	Response regulator of the LytR AlgR family
AWC36_RS01475	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AWC36_RS01480	COG0287	Prephenate dehydrogenase
AWC36_RS01480	COG1605	Chorismate mutase
AWC36_RS01485	COG1605	Chorismate mutase
AWC36_RS01485	COG0077	Prephenate dehydratase
AWC36_RS01490	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AWC36_RS01495	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AWC36_RS01505	COG0564	pseudouridine synthase activity
AWC36_RS01510	COG1496	oxidoreductase activity
AWC36_RS01515	COG0542	response to heat
AWC36_RS01550	COG3021	interspecies interaction between organisms
AWC36_RS01560	COG0741	lytic transglycosylase activity
AWC36_RS01560	COG1388	LysM domain
AWC36_RS01565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWC36_RS01570	COG2226	methyltransferase
AWC36_RS01575	COG0328	RNA-DNA hybrid ribonuclease activity
AWC36_RS01580	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AWC36_RS01600	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AWC36_RS01610	COG1780	Probably involved in ribonucleotide reductase function
AWC36_RS01615	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AWC36_RS01620	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AWC36_RS01625	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AWC36_RS01640	COG3842	ATPase activity
AWC36_RS01660	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AWC36_RS01665	COG0288	reversible hydration of carbon dioxide
AWC36_RS01670	COG1131	(ABC) transporter
AWC36_RS01675	COG0842	Transport permease protein
AWC36_RS01680	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AWC36_RS01685	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AWC36_RS01690	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AWC36_RS01695	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AWC36_RS01700	COG0617	tRNA 3'-terminal CCA addition
AWC36_RS01705	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AWC36_RS01715	COG1489	DNA binding
AWC36_RS01720	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AWC36_RS01725	COG1643	Atp-dependent helicase
AWC36_RS01730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AWC36_RS01740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWC36_RS01745	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AWC36_RS01750	COG0316	Belongs to the HesB IscA family
AWC36_RS01760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWC36_RS01765	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AWC36_RS01770	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AWC36_RS01775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWC36_RS01780	COG3835	regulator
AWC36_RS01785	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AWC36_RS01795	COG4208	sulfate ABC transporter
AWC36_RS01800	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AWC36_RS01825	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AWC36_RS01840	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AWC36_RS01845	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
AWC36_RS01855	COG0513	Belongs to the DEAD box helicase family
AWC36_RS01860	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AWC36_RS01865	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AWC36_RS01875	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
AWC36_RS01880	COG3026	antisigma factor binding
AWC36_RS01885	COG3086	response to oxidative stress
AWC36_RS01890	COG0481	GTPase activity
AWC36_RS01900	COG0571	ribonuclease III activity
AWC36_RS01905	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AWC36_RS01910	COG1381	Involved in DNA repair and RecF pathway recombination
AWC36_RS01915	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AWC36_RS01920	COG0736	holo-[acyl-carrier-protein] synthase activity
AWC36_RS01925	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AWC36_RS01930	COG2200	EAL domain
AWC36_RS01955	COG4964	Belongs to the GSP D family
AWC36_RS02005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWC36_RS02015	COG1538	Outer membrane efflux protein
AWC36_RS02040	COG0560	Phosphoserine phosphatase
AWC36_RS02050	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AWC36_RS02055	COG0047	phosphoribosylformylglycinamidine synthase activity
AWC36_RS02055	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AWC36_RS02060	COG2205	protein histidine kinase activity
AWC36_RS02070	COG2204	response regulator
AWC36_RS02075	COG0347	Belongs to the P(II) protein family
AWC36_RS02085	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AWC36_RS02090	COG2814	Major facilitator Superfamily
AWC36_RS02095	COG3683	transport system, periplasmic component
AWC36_RS02100	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AWC36_RS02110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWC36_RS02120	COG0483	inositol monophosphate 1-phosphatase activity
AWC36_RS02125	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AWC36_RS02130	COG1959	2 iron, 2 sulfur cluster binding
AWC36_RS02140	COG0822	iron-sulfur transferase activity
AWC36_RS02145	COG0316	Belongs to the HesB IscA family
AWC36_RS02150	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AWC36_RS02155	COG0443	Heat shock 70 kDa protein
AWC36_RS02160	COG0633	Ferredoxin
AWC36_RS02165	COG2975	iron-sulfur cluster assembly
AWC36_RS02170	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AWC36_RS02180	COG2897	thiosulfate sulfurtransferase activity
AWC36_RS02185	COG0105	UTP biosynthetic process
AWC36_RS02190	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AWC36_RS02200	COG1426	Protein conserved in bacteria
AWC36_RS02205	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AWC36_RS02210	COG0124	histidyl-tRNA synthetase
AWC36_RS02215	COG2976	Protein conserved in bacteria
AWC36_RS02220	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AWC36_RS02225	COG1160	GTP binding
AWC36_RS02235	COG1645	bacterial-type flagellum-dependent swarming motility
AWC36_RS02260	COG1570	exodeoxyribonuclease VII activity
AWC36_RS02265	COG0516	GMP reductase activity
AWC36_RS02265	COG0517	IMP dehydrogenase activity
AWC36_RS02270	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AWC36_RS02270	COG0519	Catalyzes the synthesis of GMP from XMP
AWC36_RS02280	COG3423	Transcriptional regulator
AWC36_RS02310	COG3069	C4-dicarboxylate transmembrane transporter activity
AWC36_RS02330	COG1349	DNA-binding transcription factor activity
AWC36_RS02335	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AWC36_RS02340	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
AWC36_RS02345	COG1309	transcriptional regulator
AWC36_RS02380	COG4977	sequence-specific DNA binding
AWC36_RS02385	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AWC36_RS02390	COG1609	Transcriptional regulator
AWC36_RS02415	COG3833	ABC-type maltose transport systems, permease component
AWC36_RS02425	COG2814	Major facilitator Superfamily
AWC36_RS02430	COG1566	PFAM secretion protein HlyD family protein
AWC36_RS02440	COG0425	Belongs to the sulfur carrier protein TusA family
AWC36_RS02465	COG0583	DNA-binding transcription factor activity
AWC36_RS02485	COG2249	NAD(P)H dehydrogenase (quinone) activity
AWC36_RS02520	COG1609	Transcriptional regulator
AWC36_RS02525	COG0747	negative chemotaxis
AWC36_RS02530	COG0601	transmembrane transport
AWC36_RS02535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWC36_RS02540	COG4608	Belongs to the ABC transporter superfamily
AWC36_RS02545	COG0444	Belongs to the ABC transporter superfamily
AWC36_RS02550	COG0154	amidase activity
AWC36_RS02555	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AWC36_RS02560	COG0351	phosphomethylpyrimidine kinase
AWC36_RS02565	COG1830	Aldolase
AWC36_RS02570	COG3223	Belongs to the PsiE family
AWC36_RS02575	COG1597	lipid kinase activity
AWC36_RS02580	COG0826	peptidase U32
AWC36_RS02585	COG0435	Glutathione S-transferase
AWC36_RS02590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWC36_RS02610	COG0745	RESPONSE REGULATOR receiver
AWC36_RS02615	COG2205	protein histidine kinase activity
AWC36_RS02620	COG0477	Major facilitator Superfamily
AWC36_RS02625	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AWC36_RS02630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AWC36_RS02635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWC36_RS02645	COG3265	gluconokinase activity
AWC36_RS02650	COG1028	Short-chain dehydrogenase reductase Sdr
AWC36_RS02655	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWC36_RS02670	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AWC36_RS02675	COG3048	D-serine ammonia-lyase activity
AWC36_RS02680	COG1609	Transcriptional regulator
AWC36_RS02690	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AWC36_RS02715	COG2239	Acts as a magnesium transporter
AWC36_RS02730	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AWC36_RS02740	COG0581	inorganic phosphate transmembrane transporter activity
AWC36_RS02745	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AWC36_RS02755	COG1760	l-serine dehydratase
AWC36_RS02760	COG0814	amino acid
AWC36_RS02765	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AWC36_RS02770	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AWC36_RS02775	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AWC36_RS02780	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AWC36_RS02790	COG0215	cysteine-tRNA ligase activity
AWC36_RS02795	COG2501	S4 domain
AWC36_RS02800	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AWC36_RS02815	COG1447	Phosphotransferase system cellobiose-specific component IIA
AWC36_RS02825	COG4122	O-methyltransferase activity
AWC36_RS02835	COG3264	Mechanosensitive ion channel
AWC36_RS02835	COG1511	domain protein
AWC36_RS02845	COG4948	Mandelate Racemase Muconate Lactonizing
AWC36_RS02865	COG0436	Aminotransferase
AWC36_RS02870	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AWC36_RS02875	COG0513	Belongs to the DEAD box helicase family
AWC36_RS02880	COG3300	MHYT domain
AWC36_RS02880	COG5001	Diguanylate cyclase
AWC36_RS02885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWC36_RS02895	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AWC36_RS02905	COG0246	Mannitol dehydrogenase
AWC36_RS02910	COG2354	Protein conserved in bacteria
AWC36_RS02925	COG2916	Histone family protein nucleoid-structuring protein H-NS
AWC36_RS02940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWC36_RS02955	COG2116	formate transmembrane transporter activity
AWC36_RS02965	COG0579	oxidoreductase
AWC36_RS02970	COG3691	Protein conserved in bacteria
AWC36_RS03000	COG2062	phosphohistidine phosphatase, SixA
AWC36_RS03005	COG2840	Smr protein MutS2
AWC36_RS03010	COG2890	protein-(glutamine-N5) methyltransferase activity
AWC36_RS03015	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AWC36_RS03020	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AWC36_RS03025	COG0730	response to heat
AWC36_RS03030	COG3101	peptidyl-lysine hydroxylation
AWC36_RS03055	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AWC36_RS03055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWC36_RS03060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AWC36_RS03075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AWC36_RS03080	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AWC36_RS03085	COG0101	tRNA pseudouridine synthase activity
AWC36_RS03090	COG0586	Pfam SNARE associated Golgi protein
AWC36_RS03100	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AWC36_RS03105	COG0285	dihydrofolate synthase activity
AWC36_RS03110	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AWC36_RS03115	COG1286	toxin biosynthetic process
AWC36_RS03120	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AWC36_RS03125	COG0163	prenyltransferase activity
AWC36_RS03130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWC36_RS03140	COG4215	(ABC) transporter
AWC36_RS03145	COG4160	amino acid transport
AWC36_RS03150	COG4598	ABC transporter
AWC36_RS03155	COG1090	epimerase
AWC36_RS03160	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AWC36_RS03165	COG0531	amino acid
AWC36_RS03170	COG4303	Ethanolamine ammonia lyase large subunit
AWC36_RS03175	COG4302	ethanolamine ammonia-lyase activity
AWC36_RS03180	COG0622	Phosphoesterase
AWC36_RS03185	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AWC36_RS03190	COG3037	sugar-specific permease SgaT UlaA
AWC36_RS03200	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWC36_RS03205	COG1609	Transcriptional regulator
AWC36_RS03210	COG0280	phosphate acetyltransferase
AWC36_RS03210	COG0857	belongs to the CobB CobQ family
AWC36_RS03215	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AWC36_RS03220	COG3092	negative regulation of chromosome organization
AWC36_RS03225	COG3013	Belongs to the UPF0304 family
AWC36_RS03230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AWC36_RS03235	COG0471	metal ion transport
AWC36_RS03235	COG0490	domain, Protein
AWC36_RS03240	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AWC36_RS03245	COG0436	Aminotransferase
AWC36_RS03250	COG0583	DNA-binding transcription factor activity
AWC36_RS03260	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWC36_RS03265	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWC36_RS03265	COG0649	NAD binding
AWC36_RS03270	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AWC36_RS03275	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AWC36_RS03285	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AWC36_RS03290	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWC36_RS03295	COG0839	Belongs to the complex I subunit 6 family
AWC36_RS03300	COG0713	ATP synthesis coupled electron transport
AWC36_RS03305	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AWC36_RS03310	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWC36_RS03315	COG1007	ATP synthesis coupled electron transport
AWC36_RS03320	COG4575	ribosome binding
AWC36_RS03325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWC36_RS03330	COG0384	phenazine biosynthesis protein PhzF
AWC36_RS03335	COG0488	(ABC) transporter
AWC36_RS03340	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AWC36_RS03345	COG0437	4 iron, 4 sulfur cluster binding
AWC36_RS03350	COG5557	Pfam Polysulphide reductase, NrfD
AWC36_RS03355	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AWC36_RS03360	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AWC36_RS03365	COG1773	rubredoxin
AWC36_RS03375	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AWC36_RS03380	COG0298	carbon dioxide binding
AWC36_RS03385	COG0409	Hydrogenase expression formation protein
AWC36_RS03390	COG0309	Hydrogenase expression formation protein (HypE)
AWC36_RS03395	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AWC36_RS03435	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AWC36_RS03435	COG0519	Catalyzes the synthesis of GMP from XMP
AWC36_RS03445	COG3383	formate dehydrogenase (NAD+) activity
AWC36_RS03445	COG0243	molybdopterin cofactor binding
AWC36_RS03450	COG0437	4 iron, 4 sulfur cluster binding
AWC36_RS03455	COG2864	formate dehydrogenase
AWC36_RS03460	COG3058	Necessary for formate dehydrogenase activity
AWC36_RS03470	COG2814	Major facilitator Superfamily
AWC36_RS03480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWC36_RS03485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AWC36_RS03500	COG2149	membrane
AWC36_RS03505	COG2999	glutathione oxidoreductase activity
AWC36_RS03515	COG0840	transmembrane signaling receptor activity
AWC36_RS03530	COG4807	Protein conserved in bacteria
AWC36_RS03535	COG0789	Transcriptional regulator
AWC36_RS03540	COG0626	cystathionine gamma-synthase activity
AWC36_RS03565	COG2011	ABC-type metal ion transport system permease component
AWC36_RS03575	COG0457	Tetratricopeptide repeat
AWC36_RS03580	COG0726	polysaccharide deacetylase
AWC36_RS03580	COG1649	PFAM Uncharacterised BCR, COG1649
AWC36_RS03585	COG1215	transferase activity, transferring glycosyl groups
AWC36_RS03595	COG2885	chlorophyll binding
AWC36_RS03600	COG2199	diguanylate cyclase activity
AWC36_RS03620	COG2814	Major facilitator Superfamily
AWC36_RS03625	COG0673	inositol 2-dehydrogenase activity
AWC36_RS03630	COG1082	Xylose isomerase domain protein TIM barrel
AWC36_RS03635	COG0673	inositol 2-dehydrogenase activity
AWC36_RS03655	COG1737	Transcriptional regulator
AWC36_RS03655	COG0837	glucose binding
AWC36_RS03660	COG3718	enzyme involved in inositol metabolism
AWC36_RS03665	COG1012	belongs to the aldehyde dehydrogenase family
AWC36_RS03675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWC36_RS03680	COG0673	inositol 2-dehydrogenase activity
AWC36_RS03685	COG1082	Xylose isomerase domain protein TIM barrel
AWC36_RS03690	COG1802	Transcriptional regulator
AWC36_RS03715	COG1560	Kdo2-lipid A biosynthetic process
AWC36_RS03720	COG3459	Glycosyltransferase 36 associated
AWC36_RS03730	COG4977	sequence-specific DNA binding
AWC36_RS03745	COG2375	cellular response to nickel ion
AWC36_RS03750	COG1695	Transcriptional regulator
AWC36_RS03755	COG3038	cytochrome b561
AWC36_RS03785	COG2144	transferase activity, transferring acyl groups
AWC36_RS03795	COG2072	flavoprotein involved in K transport
AWC36_RS03805	COG0747	negative chemotaxis
AWC36_RS03810	COG0601	transmembrane transport
AWC36_RS03815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWC36_RS03825	COG0154	amidase activity
AWC36_RS03830	COG0157	Belongs to the NadC ModD family
AWC36_RS03845	COG0640	Transcriptional regulator
AWC36_RS03855	COG1473	amidohydrolase
AWC36_RS03870	COG1126	abc transporter atp-binding protein
AWC36_RS03875	COG0765	amino acid transport
AWC36_RS03880	COG0765	amino acid transport
AWC36_RS03885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWC36_RS03910	COG0405	Gamma-glutamyltransferase
AWC36_RS03915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWC36_RS03930	COG2186	Transcriptional regulator
AWC36_RS03935	COG0740	serine-type endopeptidase activity
AWC36_RS03980	COG3675	Pfam Lipase (class 3)
AWC36_RS04135	COG0673	inositol 2-dehydrogenase activity
AWC36_RS04145	COG2814	Major facilitator Superfamily
AWC36_RS04150	COG3962	Belongs to the TPP enzyme family
AWC36_RS04155	COG0673	inositol 2-dehydrogenase activity
AWC36_RS04170	COG2814	Major facilitator Superfamily
AWC36_RS04170	COG0477	Major facilitator Superfamily
AWC36_RS04180	COG0673	inositol 2-dehydrogenase activity
AWC36_RS04185	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AWC36_RS04190	COG3958	Transketolase
AWC36_RS04210	COG1082	Xylose isomerase domain protein TIM barrel
AWC36_RS04220	COG1454	alcohol dehydrogenase
AWC36_RS04230	COG0427	acetyl-CoA hydrolase
AWC36_RS04235	COG1960	acyl-CoA dehydrogenase activity
AWC36_RS04240	COG1960	acyl-CoA dehydrogenase activity
AWC36_RS04245	COG2086	electron transfer activity
AWC36_RS04255	COG0644	oxidoreductase
AWC36_RS04265	COG0183	Belongs to the thiolase family
AWC36_RS04270	COG1250	3-hydroxyacyl-CoA dehydrogenase
AWC36_RS04275	COG1024	Enoyl-CoA hydratase
AWC36_RS04280	COG1309	transcriptional regulator
AWC36_RS04300	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AWC36_RS04300	COG3008	intermembrane lipid transfer
AWC36_RS04305	COG2995	paraquat-inducible protein a
AWC36_RS04315	COG3713	MltA-interacting MipA family protein
AWC36_RS04325	COG0523	cobalamin synthesis protein
AWC36_RS04345	COG2390	Transcriptional regulator
AWC36_RS04350	COG0149	triose-phosphate isomerase activity
AWC36_RS04355	COG2376	Dihydroxyacetone kinase
AWC36_RS04360	COG0698	ribose 5-phosphate isomerase
AWC36_RS04365	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AWC36_RS04370	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AWC36_RS04370	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AWC36_RS04380	COG2271	Major facilitator Superfamily
AWC36_RS04385	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWC36_RS04400	COG3048	D-serine ammonia-lyase activity
AWC36_RS04410	COG3228	Belongs to the MtfA family
AWC36_RS04420	COG0071	Belongs to the small heat shock protein (HSP20) family
AWC36_RS04425	COG0401	homolog of Blt101
AWC36_RS04435	COG3706	GGDEF domain
AWC36_RS04455	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AWC36_RS04460	COG0303	'Molybdopterin
AWC36_RS04465	COG4172	Belongs to the ABC transporter superfamily
AWC36_RS04470	COG0747	negative chemotaxis
AWC36_RS04475	COG0601	transmembrane transport
AWC36_RS04480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWC36_RS04485	COG0281	malic enzyme
AWC36_RS04490	COG0295	cytidine deaminase activity
AWC36_RS04495	COG1346	cytolysis
AWC36_RS04500	COG1380	Effector of murein hydrolase LrgA
AWC36_RS04510	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AWC36_RS04515	COG0156	8-amino-7-oxononanoate synthase activity
AWC36_RS04520	COG2226	methyltransferase
AWC36_RS04525	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AWC36_RS04530	COG0556	nucleotide-excision repair
AWC36_RS04545	COG0318	PFAM AMP-dependent synthetase and ligase
AWC36_RS04560	COG0604	alcohol dehydrogenase
AWC36_RS04570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWC36_RS04575	COG1116	anion transmembrane transporter activity
AWC36_RS04590	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AWC36_RS04595	COG0521	Mo-molybdopterin cofactor biosynthetic process
AWC36_RS04600	COG0315	cyclic pyranopterin monophosphate synthase activity
AWC36_RS04605	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AWC36_RS04610	COG0314	molybdopterin synthase activity
AWC36_RS04615	COG0670	Belongs to the BI1 family
AWC36_RS04625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWC36_RS04640	COG0842	Transport permease protein
AWC36_RS04645	COG0842	Transport permease protein
AWC36_RS04650	COG1131	(ABC) transporter
AWC36_RS04660	COG1309	transcriptional regulator
AWC36_RS04670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWC36_RS04675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWC36_RS04680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWC36_RS04685	COG1120	ATPase activity
AWC36_RS04695	COG0513	Belongs to the DEAD box helicase family
AWC36_RS04720	COG1538	Outer membrane efflux protein
AWC36_RS04730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWC36_RS04740	COG3547	Transposase (IS116 IS110 IS902 family)
AWC36_RS04750	COG2195	Cleaves the N-terminal amino acid of tripeptides
AWC36_RS04755	COG0747	negative chemotaxis
AWC36_RS04760	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AWC36_RS04765	COG2040	homocysteine
AWC36_RS04780	COG1053	succinate dehydrogenase
AWC36_RS04790	COG0431	NADPH-dependent FMN reductase
AWC36_RS04790	COG1053	succinate dehydrogenase
AWC36_RS04790	COG3976	FMN-binding domain protein
AWC36_RS04815	COG1686	Belongs to the peptidase S11 family
AWC36_RS04825	COG1349	DNA-binding transcription factor activity
AWC36_RS04840	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AWC36_RS04870	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AWC36_RS04880	COG1126	abc transporter atp-binding protein
AWC36_RS04885	COG0765	amino acid transport
AWC36_RS04890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWC36_RS04895	COG0783	Belongs to the Dps family
AWC36_RS04910	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AWC36_RS04915	COG0697	spore germination
AWC36_RS04925	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AWC36_RS04930	COG1984	allophanate hydrolase subunit 2
AWC36_RS04935	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AWC36_RS04950	COG0436	Aminotransferase
AWC36_RS04955	COG1176	ABC-type spermidine putrescine transport system, permease component I
AWC36_RS04960	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AWC36_RS04970	COG3842	ATPase activity
AWC36_RS04985	COG4221	oxidoreductase activity
AWC36_RS04990	COG0765	amino acid transport
AWC36_RS04995	COG0765	amino acid transport
AWC36_RS05005	COG0534	Mate efflux family protein
AWC36_RS05200	COG4626	Terminase
AWC36_RS05200	COG1802	Transcriptional regulator
AWC36_RS05205	COG4695	Portal protein
AWC36_RS05320	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AWC36_RS05340	COG3082	Protein of unknown function (DUF1414)
AWC36_RS05345	COG3081	Nucleoid-associated protein
AWC36_RS05360	COG2979	Protein of unknown function (DUF533)
AWC36_RS05365	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AWC36_RS05370	COG1067	ATP-dependent peptidase activity
AWC36_RS05385	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
AWC36_RS05390	COG3070	regulator of competence-specific genes
AWC36_RS05395	COG1289	transmembrane transporter activity
AWC36_RS05400	COG3304	Inner membrane component domain
AWC36_RS05405	COG0210	DNA helicase
AWC36_RS05410	COG1803	Methylglyoxal synthase
AWC36_RS05420	COG1832	CoA-binding protein
AWC36_RS05425	COG3785	DNA binding
AWC36_RS05430	COG1254	Belongs to the acylphosphatase family
AWC36_RS05435	COG2920	part of a sulfur-relay system
AWC36_RS05440	COG0670	Belongs to the BI1 family
AWC36_RS05475	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AWC36_RS05480	COG1683	Conserved Protein
AWC36_RS05515	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AWC36_RS05520	COG2943	transferase activity, transferring hexosyl groups
AWC36_RS05525	COG2814	Major facilitator Superfamily
AWC36_RS05530	COG1560	Kdo2-lipid A biosynthetic process
AWC36_RS05535	COG1902	pentaerythritol trinitrate reductase activity
AWC36_RS05540	COG1054	Belongs to the UPF0176 family
AWC36_RS05545	COG2353	YceI-like domain
AWC36_RS05550	COG3038	cytochrome b561
AWC36_RS05570	COG0418	dihydroorotase activity
AWC36_RS05580	COG1530	ribonuclease E activity
AWC36_RS05585	COG0564	pseudouridine synthase activity
AWC36_RS05590	COG0424	maF-like protein
AWC36_RS05595	COG1399	metal-binding, possibly nucleic acid-binding protein
AWC36_RS05600	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AWC36_RS05605	COG0416	fatty acid biosynthetic process
AWC36_RS05610	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AWC36_RS05625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AWC36_RS05630	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AWC36_RS05635	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AWC36_RS05640	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AWC36_RS05645	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AWC36_RS05650	COG0470	DNA polymerase III
AWC36_RS05655	COG0084	hydrolase, TatD family'
AWC36_RS05660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWC36_RS05660	COG1263	PTS System
AWC36_RS05675	COG0537	adenosine 5'-monophosphoramidase activity
AWC36_RS05680	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
AWC36_RS05690	COG1472	Belongs to the glycosyl hydrolase 3 family
AWC36_RS05695	COG3150	esterase
AWC36_RS05700	COG1252	NADH dehydrogenase
AWC36_RS05705	COG3134	Outer membrane lipoprotein
AWC36_RS05715	COG0443	Heat shock 70 kDa protein
AWC36_RS05725	COG1785	Belongs to the alkaline phosphatase family
AWC36_RS05735	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AWC36_RS05740	COG4591	ABC-type transport system involved in lipoprotein release permease component
AWC36_RS05745	COG1136	(ABC) transporter
AWC36_RS05750	COG4591	ABC-type transport system involved in lipoprotein release permease component
AWC36_RS05755	COG1940	carbohydrate kinase activity
AWC36_RS05770	COG4139	cobalamin transport
AWC36_RS05775	COG0386	Belongs to the glutathione peroxidase family
AWC36_RS05780	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
AWC36_RS05785	COG0791	NLP P60 protein
AWC36_RS05790	COG0095	Lipoate-protein ligase
AWC36_RS05805	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AWC36_RS05810	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AWC36_RS05815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWC36_RS05820	COG4558	Periplasmic binding protein
AWC36_RS05825	COG3720	iron ion transport
AWC36_RS05830	COG1414	Transcriptional regulator
AWC36_RS05835	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AWC36_RS05840	COG0129	dihydroxy-acid dehydratase activity
AWC36_RS05845	COG2610	gluconate transmembrane transporter activity
AWC36_RS05850	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AWC36_RS05855	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AWC36_RS05855	COG0574	Belongs to the PEP-utilizing enzyme family
AWC36_RS05860	COG1477	protein flavinylation
AWC36_RS05870	COG0628	permease
AWC36_RS05875	COG0277	FAD linked oxidase domain protein
AWC36_RS05875	COG0247	lactate metabolic process
AWC36_RS05880	COG2050	protein possibly involved in aromatic compounds catabolism
AWC36_RS05890	COG0316	Belongs to the HesB IscA family
AWC36_RS05895	COG0719	Fe-S assembly protein
AWC36_RS05900	COG0396	ATPase activity
AWC36_RS05905	COG0719	Fe-S assembly protein
AWC36_RS05910	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AWC36_RS05915	COG2166	iron-sulfur cluster assembly
AWC36_RS05920	COG1376	ErfK ybiS ycfS ynhG family protein
AWC36_RS05920	COG1388	LysM domain
AWC36_RS05925	COG4238	major outer membrane lipoprotein
AWC36_RS05970	COG4608	Belongs to the ABC transporter superfamily
AWC36_RS05975	COG0444	Belongs to the ABC transporter superfamily
AWC36_RS05980	COG1028	Short-chain dehydrogenase reductase Sdr
AWC36_RS05985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWC36_RS05995	COG0747	negative chemotaxis
AWC36_RS06005	COG1215	transferase activity, transferring glycosyl groups
AWC36_RS06030	COG0840	transmembrane signaling receptor activity
AWC36_RS06035	COG0318	PFAM AMP-dependent synthetase and ligase
AWC36_RS06040	COG1012	belongs to the aldehyde dehydrogenase family
AWC36_RS06045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWC36_RS06050	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWC36_RS06055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWC36_RS06060	COG1116	anion transmembrane transporter activity
AWC36_RS06065	COG1882	Formate acetyltransferase
AWC36_RS06070	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AWC36_RS06080	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AWC36_RS06085	COG2873	o-acetylhomoserine
AWC36_RS06100	COG4948	Mandelate Racemase Muconate Lactonizing
AWC36_RS06115	COG2271	Major facilitator Superfamily
AWC36_RS06120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWC36_RS06125	COG1942	4-Oxalocrotonate Tautomerase
AWC36_RS06135	COG1414	Transcriptional regulator
AWC36_RS06140	COG3734	2-keto-3-deoxy-galactonokinase
AWC36_RS06145	COG0800	Aldolase
AWC36_RS06180	COG4771	TonB-dependent receptor
AWC36_RS06185	COG1169	isochorismate synthase
AWC36_RS06190	COG1021	2,3-dihydroxybenzoate-AMP ligase
AWC36_RS06195	COG3433	isochorismatase activity
AWC36_RS06195	COG1535	isochorismatase
AWC36_RS06200	COG1028	Short-chain dehydrogenase reductase Sdr
AWC36_RS06205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWC36_RS06210	COG3433	isochorismatase activity
AWC36_RS06210	COG1535	isochorismatase
AWC36_RS06215	COG0477	Major facilitator Superfamily
AWC36_RS06225	COG2223	nitrite transmembrane transporter activity
AWC36_RS06240	COG0431	NADPH-dependent FMN reductase
AWC36_RS06245	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AWC36_RS06255	COG4172	Belongs to the ABC transporter superfamily
AWC36_RS06270	COG0747	negative chemotaxis
AWC36_RS06285	COG2072	flavoprotein involved in K transport
AWC36_RS06295	COG1126	abc transporter atp-binding protein
AWC36_RS06300	COG0765	amino acid transport
AWC36_RS06305	COG0765	amino acid transport
AWC36_RS06315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AWC36_RS06330	COG0583	DNA-binding transcription factor activity
AWC36_RS06345	COG1028	Short-chain dehydrogenase reductase Sdr
AWC36_RS06345	COG0604	alcohol dehydrogenase
AWC36_RS06345	COG3321	synthase
AWC36_RS06360	COG0601	transmembrane transport
AWC36_RS06365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWC36_RS06370	COG0444	Belongs to the ABC transporter superfamily
AWC36_RS06375	COG4608	Belongs to the ABC transporter superfamily
AWC36_RS06380	COG0318	PFAM AMP-dependent synthetase and ligase
AWC36_RS06390	COG1473	amidohydrolase
AWC36_RS06395	COG1309	transcriptional regulator
AWC36_RS06400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AWC36_RS06405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWC36_RS06410	COG0300	oxidoreductase activity
AWC36_RS06415	COG4172	Belongs to the ABC transporter superfamily
AWC36_RS06420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWC36_RS06430	COG0747	negative chemotaxis
AWC36_RS06440	COG1464	Belongs to the NlpA lipoprotein family
AWC36_RS06445	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AWC36_RS06450	COG2011	ABC-type metal ion transport system permease component
AWC36_RS06460	COG4166	transmembrane transport
AWC36_RS06465	COG0601	transmembrane transport
AWC36_RS06475	COG0444	Belongs to the ABC transporter superfamily
AWC36_RS06485	COG1695	Transcriptional regulator
AWC36_RS06495	COG2205	protein histidine kinase activity
AWC36_RS06495	COG3437	response regulator, receiver
AWC36_RS06495	COG3850	Histidine kinase
AWC36_RS06495	COG4999	Histidine kinase
AWC36_RS06505	COG0840	transmembrane signaling receptor activity
AWC36_RS06520	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AWC36_RS06570	COG1028	Short-chain dehydrogenase reductase Sdr
AWC36_RS06575	COG1028	Short-chain dehydrogenase reductase Sdr
AWC36_RS06580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWC36_RS06585	COG1301	dicarboxylic acid transport
AWC36_RS06590	COG0477	Major facilitator Superfamily
AWC36_RS06605	COG1429	ligase activity, forming nitrogen-metal bonds
AWC36_RS06610	COG4771	TonB-dependent receptor
AWC36_RS06620	COG0534	Mate efflux family protein
AWC36_RS06625	COG0307	riboflavin synthase, alpha
AWC36_RS06630	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AWC36_RS06635	COG1609	Transcriptional regulator
AWC36_RS06645	COG0791	NLP P60 protein
AWC36_RS06650	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AWC36_RS06655	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AWC36_RS06665	COG3313	Fe-S protein
AWC36_RS06670	COG1846	Transcriptional regulator
AWC36_RS06680	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AWC36_RS06685	COG3895	Periplasmic Protein
AWC36_RS06690	COG0259	pyridoxamine-phosphate oxidase activity
AWC36_RS06695	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AWC36_RS06700	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AWC36_RS06705	COG0625	glutathione transferase activity
AWC36_RS06720	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AWC36_RS06725	COG0671	phosphoesterase, PA-phosphatase related
AWC36_RS06730	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AWC36_RS06735	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AWC36_RS06740	COG0284	orotidine-5'-phosphate decarboxylase activity
AWC36_RS06745	COG0023	Translation Initiation Factor
AWC36_RS06755	COG0235	Class ii aldolase
AWC36_RS06760	COG1966	Carbon starvation protein
AWC36_RS06765	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AWC36_RS06790	COG0243	molybdopterin cofactor binding
AWC36_RS06795	COG1263	PTS System
AWC36_RS06795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWC36_RS06800	COG1486	melibiose metabolic process
AWC36_RS06805	COG2188	Transcriptional regulator
AWC36_RS06810	COG0583	DNA-binding transcription factor activity
AWC36_RS06820	COG2271	Major facilitator Superfamily
AWC36_RS06875	COG2211	Major facilitator Superfamily
AWC36_RS06885	COG0583	DNA-binding transcription factor activity
AWC36_RS06890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AWC36_RS06935	COG1446	asparaginase
AWC36_RS06950	COG1028	Short-chain dehydrogenase reductase Sdr
AWC36_RS06955	COG0601	transmembrane transport
AWC36_RS06960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWC36_RS06965	COG0444	Belongs to the ABC transporter superfamily
AWC36_RS06970	COG4608	Belongs to the ABC transporter superfamily
AWC36_RS07005	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AWC36_RS07010	COG1842	Phage shock protein A
AWC36_RS07020	COG1983	PspC domain protein
AWC36_RS07030	COG3106	COG3106 Predicted ATPase
AWC36_RS07035	COG3768	UPF0283 membrane protein
AWC36_RS07040	COG4977	sequence-specific DNA binding
AWC36_RS07050	COG2211	Major facilitator Superfamily
AWC36_RS07065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWC36_RS07070	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AWC36_RS07075	COG2866	Carboxypeptidase
AWC36_RS07085	COG4166	transmembrane transport
AWC36_RS07090	COG0598	Magnesium transport protein CorA
AWC36_RS07095	COG1126	abc transporter atp-binding protein
AWC36_RS07100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWC36_RS07105	COG0625	glutathione transferase activity
AWC36_RS07115	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AWC36_RS07125	COG0765	amino acid transport
AWC36_RS07130	COG0765	amino acid transport
AWC36_RS07140	COG0037	tRNA processing
AWC36_RS07155	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWC36_RS07160	COG2911	Protein conserved in bacteria
AWC36_RS07170	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AWC36_RS07175	COG1643	Atp-dependent helicase
AWC36_RS07195	COG3591	Belongs to the peptidase S1B family
AWC36_RS07210	COG2223	nitrite transmembrane transporter activity
AWC36_RS07220	COG2205	protein histidine kinase activity
AWC36_RS07225	COG0745	RESPONSE REGULATOR receiver
AWC36_RS07240	COG0659	secondary active sulfate transmembrane transporter activity
AWC36_RS07245	COG0387	Pfam Sodium calcium exchanger
AWC36_RS07250	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AWC36_RS07265	COG2261	transglycosylase associated protein
AWC36_RS07270	COG3842	ATPase activity
AWC36_RS07280	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AWC36_RS07285	COG1012	belongs to the aldehyde dehydrogenase family
AWC36_RS07295	COG1176	ABC-type spermidine putrescine transport system, permease component I
AWC36_RS07310	COG0671	phosphoesterase, PA-phosphatase related
AWC36_RS07315	COG2814	Major facilitator Superfamily
AWC36_RS07325	COG0583	DNA-binding transcription factor activity
AWC36_RS07330	COG2831	hemolysin activation secretion protein
AWC36_RS07335	COG3210	domain, Protein
AWC36_RS07335	COG3210	domain, Protein
AWC36_RS07365	COG3210	domain, Protein
AWC36_RS07380	COG4948	Mandelate Racemase Muconate Lactonizing
AWC36_RS07385	COG1464	Belongs to the NlpA lipoprotein family
AWC36_RS07395	COG0583	DNA-binding transcription factor activity
AWC36_RS07400	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AWC36_RS07460	COG0277	FAD linked oxidase domain protein
AWC36_RS07520	COG2914	Belongs to the UPF0125 (RnfH) family
AWC36_RS07540	COG4656	Part of a membrane complex involved in electron transport
AWC36_RS07550	COG4657	Part of a membrane complex involved in electron transport
AWC36_RS07560	COG2205	protein histidine kinase activity
AWC36_RS07590	COG0583	DNA-binding transcription factor activity
AWC36_RS07595	COG1280	lysine exporter protein (LysE YggA)
AWC36_RS07610	COG0012	GTP binding
AWC36_RS07615	COG0193	aminoacyl-tRNA hydrolase activity
AWC36_RS07630	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AWC36_RS07635	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AWC36_RS07640	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AWC36_RS07645	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AWC36_RS07660	COG2912	Transglutaminase-like superfamily
AWC36_RS07665	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AWC36_RS07675	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AWC36_RS07680	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AWC36_RS07690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWC36_RS07695	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AWC36_RS07725	COG1764	response to oxidative stress
AWC36_RS07745	COG3769	mannosylglycerate metabolic process
AWC36_RS07750	COG1215	transferase activity, transferring glycosyl groups
AWC36_RS07755	COG2378	regulation of single-species biofilm formation
AWC36_RS07770	COG4221	oxidoreductase activity
AWC36_RS07785	COG2814	Major facilitator Superfamily
AWC36_RS07795	COG1940	carbohydrate kinase activity
AWC36_RS07800	COG0583	DNA-binding transcription factor activity
AWC36_RS07805	COG2814	Major facilitator Superfamily
AWC36_RS07820	COG0114	fumarate hydratase activity
AWC36_RS07825	COG1482	cell wall glycoprotein biosynthetic process
AWC36_RS07830	COG5339	Protein conserved in bacteria
AWC36_RS07840	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AWC36_RS07850	COG0385	Bile acid
AWC36_RS07855	COG0673	inositol 2-dehydrogenase activity
AWC36_RS07865	COG1172	Belongs to the binding-protein-dependent transport system permease family
AWC36_RS07870	COG1129	ABC transporter
AWC36_RS07875	COG1879	ABC-type sugar transport system periplasmic component
AWC36_RS07880	COG1069	ribulokinase activity
AWC36_RS07885	COG2160	L-arabinose isomerase activity
AWC36_RS07895	COG4657	Part of a membrane complex involved in electron transport
AWC36_RS07900	COG2878	Part of a membrane complex involved in electron transport
AWC36_RS07905	COG4656	Part of a membrane complex involved in electron transport
AWC36_RS07910	COG4658	electron transport chain
AWC36_RS07915	COG4659	FMN binding
AWC36_RS07925	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AWC36_RS07945	COG0616	signal peptide processing
AWC36_RS07950	COG1028	Short-chain dehydrogenase reductase Sdr
AWC36_RS07960	COG1187	pseudouridine synthase activity
AWC36_RS07975	COG0243	molybdopterin cofactor binding
AWC36_RS07985	COG2146	nitrite reductase [NAD(P)H] activity
AWC36_RS07985	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AWC36_RS07990	COG1116	anion transmembrane transporter activity
AWC36_RS08000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWC36_RS08005	COG3707	response regulator
AWC36_RS08010	COG0009	L-threonylcarbamoyladenylate synthase
AWC36_RS08015	COG0613	PHP domain protein
AWC36_RS08025	COG0512	Glutamine amidotransferase of anthranilate synthase
AWC36_RS08030	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AWC36_RS08040	COG0133	tryptophan synthase activity
AWC36_RS08045	COG0159	tryptophan synthase activity
AWC36_RS08050	COG3047	cAMP biosynthetic process
AWC36_RS08055	COG0727	PFAM Uncharacterised protein family (UPF0153)
AWC36_RS08065	COG2917	probably involved in intracellular septation
AWC36_RS08080	COG2350	Protein conserved in bacteria
AWC36_RS08085	COG0840	transmembrane signaling receptor activity
AWC36_RS08095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AWC36_RS08100	COG3099	Belongs to the UPF0263 family
AWC36_RS08115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWC36_RS08120	COG0601	transmembrane transport
AWC36_RS08135	COG2095	MarC family integral membrane protein
AWC36_RS08145	COG1454	alcohol dehydrogenase
AWC36_RS08145	COG1012	belongs to the aldehyde dehydrogenase family
AWC36_RS08150	COG1435	thymidine kinase activity
AWC36_RS08160	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AWC36_RS08165	COG0745	RESPONSE REGULATOR receiver
AWC36_RS08170	COG1752	Esterase of the alpha-beta hydrolase superfamily
AWC36_RS08175	COG3012	SEC-C Motif Domain Protein
AWC36_RS08180	COG0788	formyltetrahydrofolate deformylase activity
AWC36_RS08195	COG2860	membrane
AWC36_RS08200	COG0708	Exodeoxyribonuclease III
AWC36_RS08215	COG0778	Nitroreductase
AWC36_RS08220	COG0616	signal peptide processing
AWC36_RS08225	COG0252	asparaginase activity
AWC36_RS08230	COG1335	isochorismatase
AWC36_RS08235	COG3139	Protein of unknown function (DUF1315)
AWC36_RS08240	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AWC36_RS08255	COG0656	L-ascorbic acid biosynthetic process
AWC36_RS08260	COG3713	MltA-interacting MipA family protein
AWC36_RS08265	COG2766	serine protein kinase
AWC36_RS08270	COG2718	Belongs to the UPF0229 family
AWC36_RS08280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWC36_RS08285	COG2719	SpoVR family
AWC36_RS08290	COG2186	Transcriptional regulator
AWC36_RS08295	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AWC36_RS08305	COG2983	Belongs to the UPF0260 family
AWC36_RS08310	COG0179	Fumarylacetoacetate (FAA) hydrolase
AWC36_RS08320	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AWC36_RS08330	COG0850	regulation of cytokinetic process
AWC36_RS08335	COG2894	cell division
AWC36_RS08340	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AWC36_RS08345	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AWC36_RS08350	COG0318	PFAM AMP-dependent synthetase and ligase
AWC36_RS08355	COG3065	identical protein binding
AWC36_RS08365	COG1199	ATP-dependent helicase activity
AWC36_RS08370	COG0251	oxidation-reduction process
AWC36_RS08385	COG0494	nUDIX hydrolase
AWC36_RS08390	COG1760	l-serine dehydratase
AWC36_RS08395	COG1253	flavin adenine dinucleotide binding
AWC36_RS08400	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWC36_RS08400	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWC36_RS08405	COG3715	PTS system
AWC36_RS08410	COG3716	PTS system mannose fructose sorbose family IID component
AWC36_RS08415	COG4811	Protein of unknown function (DUF986)
AWC36_RS08420	COG1971	Probably functions as a manganese efflux pump
AWC36_RS08425	COG2226	methyltransferase
AWC36_RS08440	COG0803	Belongs to the bacterial solute-binding protein 9 family
AWC36_RS08445	COG1121	(ABC) transporter
AWC36_RS08450	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AWC36_RS08455	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AWC36_RS08460	COG3001	Fructosamine kinase
AWC36_RS08470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AWC36_RS08475	COG1917	Cupin 2, conserved barrel domain protein
AWC36_RS08480	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AWC36_RS08485	COG1028	Short-chain dehydrogenase reductase Sdr
AWC36_RS08495	COG1175	transmembrane transport
AWC36_RS08500	COG0395	ABC-type sugar transport system, permease component
AWC36_RS08505	COG3842	ATPase activity
AWC36_RS08510	COG1653	transport
AWC36_RS08515	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AWC36_RS08520	COG1988	membrane-bound metal-dependent
AWC36_RS08525	COG1823	symporter activity
AWC36_RS08535	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AWC36_RS08540	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AWC36_RS08550	COG1132	(ABC) transporter
AWC36_RS08555	COG0776	regulation of translation
AWC36_RS08560	COG0072	phenylalanine-tRNA ligase activity
AWC36_RS08560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWC36_RS08565	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AWC36_RS08575	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AWC36_RS08580	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AWC36_RS08585	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AWC36_RS08595	COG4939	FMN-binding domain protein
AWC36_RS08610	COG0823	Involved in the tonB-independent uptake of proteins
AWC36_RS08615	COG0501	Belongs to the peptidase M48B family
AWC36_RS08630	COG1012	belongs to the aldehyde dehydrogenase family
AWC36_RS08650	COG0538	isocitrate dehydrogenase activity
AWC36_RS08665	COG0482	sulfurtransferase activity
AWC36_RS08670	COG2915	High frequency lysogenization protein hflD homolog
AWC36_RS08675	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AWC36_RS08680	COG0745	RESPONSE REGULATOR receiver
AWC36_RS08690	COG2850	peptidyl-arginine hydroxylation
AWC36_RS08695	COG2195	Cleaves the N-terminal amino acid of tripeptides
AWC36_RS08700	COG3842	ATPase activity
AWC36_RS08710	COG1177	transmembrane transport
AWC36_RS08715	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AWC36_RS08745	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
AWC36_RS08750	COG1956	GAF domain-containing protein
AWC36_RS08755	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AWC36_RS08755	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AWC36_RS08770	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AWC36_RS08815	COG2364	Membrane
AWC36_RS08820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWC36_RS08835	COG4669	(LipO)protein
AWC36_RS08855	COG2197	response regulator
AWC36_RS08860	COG4585	Histidine kinase
AWC36_RS08910	COG4794	Type iii secretion
AWC36_RS08920	COG4792	protein secretion
AWC36_RS08940	COG3755	Protein conserved in bacteria
AWC36_RS08950	COG1528	Iron-storage protein
AWC36_RS08960	COG1770	oligopeptidase
AWC36_RS08965	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AWC36_RS08970	COG0800	Aldolase
AWC36_RS08975	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AWC36_RS08980	COG1737	Transcriptional regulator
AWC36_RS08985	COG0469	pyruvate kinase activity
AWC36_RS08990	COG1560	Kdo2-lipid A biosynthetic process
AWC36_RS08995	COG0739	heme binding
AWC36_RS09000	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AWC36_RS09005	COG1121	(ABC) transporter
AWC36_RS09010	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AWC36_RS09015	COG2255	four-way junction helicase activity
AWC36_RS09020	COG0632	four-way junction helicase activity
AWC36_RS09025	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AWC36_RS09030	COG0217	transcriptional regulatory protein
AWC36_RS09035	COG0494	nUDIX hydrolase
AWC36_RS09040	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AWC36_RS09045	COG1801	Protein of unknown function DUF72
AWC36_RS09050	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AWC36_RS09055	COG2226	methyltransferase
AWC36_RS09060	COG0500	methyltransferase
AWC36_RS09075	COG3142	Participates in the control of copper homeostasis
AWC36_RS09080	COG3102	Protein conserved in bacteria
AWC36_RS09085	COG0018	arginyl-trna synthetase
AWC36_RS09090	COG0728	peptidoglycan biosynthetic process
AWC36_RS09100	COG3132	Protein of unknown function, DUF480
AWC36_RS09105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWC36_RS09110	COG0477	Major facilitator Superfamily
AWC36_RS09115	COG2999	glutathione oxidoreductase activity
AWC36_RS09125	COG3381	protein complex oligomerization
AWC36_RS09130	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AWC36_RS09140	COG3130	regulation of translation
AWC36_RS09145	COG3009	Protein conserved in bacteria
AWC36_RS09150	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AWC36_RS09150	COG3008	intermembrane lipid transfer
AWC36_RS09155	COG2995	paraquat-inducible protein a
AWC36_RS09160	COG0488	(ABC) transporter
AWC36_RS09165	COG0116	Belongs to the methyltransferase superfamily
AWC36_RS09165	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AWC36_RS09170	COG3217	Mosc domain protein beta barrel domain protein
AWC36_RS09170	COG0633	Ferredoxin
AWC36_RS09180	COG0167	dihydroorotate dehydrogenase activity
AWC36_RS09190	COG0308	aminopeptidase N
AWC36_RS09195	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AWC36_RS09200	COG0017	Asparaginyl-tRNA synthetase
AWC36_RS09210	COG1448	Aminotransferase
AWC36_RS09220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWC36_RS09225	COG3108	Peptidase M15
AWC36_RS09230	COG2989	Protein conserved in bacteria
AWC36_RS09235	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AWC36_RS09240	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AWC36_RS09245	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
AWC36_RS09250	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AWC36_RS09255	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AWC36_RS09260	COG3173	Aminoglycoside phosphotransferase
AWC36_RS09265	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AWC36_RS09270	COG2835	tetraacyldisaccharide 4'-kinase activity
AWC36_RS09275	COG1663	tetraacyldisaccharide 4'-kinase activity
AWC36_RS09280	COG1132	(ABC) transporter
AWC36_RS09285	COG0658	competence protein
AWC36_RS09285	COG2333	competence protein COMEC
AWC36_RS09290	COG2926	Belongs to the UPF0265 family
AWC36_RS09295	COG4604	ABC transporter, ATP-binding protein
AWC36_RS09300	COG4605	iron ion homeostasis
AWC36_RS09310	COG4607	ABC-type enterochelin transport system periplasmic component
AWC36_RS09320	COG2925	Exonuclease
AWC36_RS09325	COG0531	amino acid
AWC36_RS09335	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AWC36_RS09340	COG0840	transmembrane signaling receptor activity
AWC36_RS09345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWC36_RS09350	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AWC36_RS09355	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AWC36_RS09360	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AWC36_RS09365	COG0131	Imidazoleglycerol-phosphate dehydratase
AWC36_RS09365	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AWC36_RS09370	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AWC36_RS09375	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AWC36_RS09380	COG0107	imidazoleglycerol-phosphate synthase activity
AWC36_RS09405	COG4126	flavin adenine dinucleotide binding
AWC36_RS09420	COG0776	regulation of translation
AWC36_RS09425	COG0539	negative regulation of cytoplasmic translation
AWC36_RS09430	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AWC36_RS09435	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AWC36_RS09440	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AWC36_RS09445	COG1944	ATP diphosphatase activity
AWC36_RS09450	COG2116	formate transmembrane transporter activity
AWC36_RS09455	COG1882	Formate acetyltransferase
AWC36_RS09460	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AWC36_RS09465	COG0477	Major facilitator Superfamily
AWC36_RS09470	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AWC36_RS09475	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AWC36_RS09480	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AWC36_RS09485	COG1674	ftsk spoiiie
AWC36_RS09485	COG3107	peptidoglycan biosynthetic process
AWC36_RS09500	COG0492	ferredoxin-NADP+ reductase activity
AWC36_RS09505	COG4988	ABC transporter
AWC36_RS09510	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AWC36_RS09515	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AWC36_RS09520	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AWC36_RS09525	COG0542	response to heat
AWC36_RS09530	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AWC36_RS09535	COG1278	Cold shock
AWC36_RS09540	COG3593	DNA synthesis involved in DNA repair
AWC36_RS09545	COG2431	L-lysine efflux transmembrane transporter activity
AWC36_RS09550	COG3023	N-Acetylmuramoyl-L-alanine amidase
AWC36_RS09555	COG0393	Putative heavy-metal-binding
AWC36_RS09560	COG1126	abc transporter atp-binding protein
AWC36_RS09565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWC36_RS09570	COG4215	(ABC) transporter
AWC36_RS09575	COG4160	amino acid transport
AWC36_RS09580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWC36_RS09585	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AWC36_RS09595	COG1177	transmembrane transport
AWC36_RS09600	COG1176	ABC-type spermidine putrescine transport system, permease component I
AWC36_RS09605	COG3842	ATPase activity
AWC36_RS09610	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AWC36_RS09620	COG0189	ligase activity
AWC36_RS09645	COG2985	domain, Protein
AWC36_RS09645	COG0569	domain protein
AWC36_RS09655	COG0738	Major facilitator superfamily
AWC36_RS09660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWC36_RS09665	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AWC36_RS09670	COG1349	DNA-binding transcription factor activity
AWC36_RS09675	COG1686	Belongs to the peptidase S11 family
AWC36_RS09680	COG2011	ABC-type metal ion transport system permease component
AWC36_RS09685	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AWC36_RS09690	COG1464	Belongs to the NlpA lipoprotein family
AWC36_RS09695	COG0625	glutathione transferase activity
AWC36_RS09700	COG2133	pyrroloquinoline quinone binding
AWC36_RS09705	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AWC36_RS09710	COG2949	membrane
AWC36_RS09715	COG2311	Membrane
AWC36_RS09720	COG0302	gtp cyclohydrolase
AWC36_RS09745	COG0371	Dehydrogenase
AWC36_RS09750	COG1129	ABC transporter
AWC36_RS09755	COG1172	Belongs to the binding-protein-dependent transport system permease family
AWC36_RS09760	COG4771	TonB-dependent receptor
AWC36_RS09765	COG0833	amino acid
AWC36_RS09770	COG0583	DNA-binding transcription factor activity
AWC36_RS09775	COG2855	membrane
AWC36_RS09780	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AWC36_RS09785	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AWC36_RS09785	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AWC36_RS09785	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AWC36_RS09790	COG1105	Belongs to the carbohydrate kinase PfkB family
AWC36_RS09795	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWC36_RS09795	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWC36_RS09810	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AWC36_RS09815	COG3539	Fimbrial protein
AWC36_RS09820	COG0523	cobalamin synthesis protein
AWC36_RS09825	COG0671	phosphoesterase, PA-phosphatase related
AWC36_RS09830	COG0791	NLP P60 protein
AWC36_RS09835	COG4166	transmembrane transport
AWC36_RS09840	COG4174	ABC transporter (Permease)
AWC36_RS09845	COG4239	(ABC) transporter, permease
AWC36_RS09850	COG4172	Belongs to the ABC transporter superfamily
AWC36_RS09860	COG2814	Major facilitator Superfamily
AWC36_RS09865	COG1187	pseudouridine synthase activity
AWC36_RS09875	COG1061	Type III restriction enzyme res subunit
AWC36_RS09880	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AWC36_RS09885	COG1702	phosphate starvation-inducible protein PhoH
AWC36_RS09895	COG1191	sigma factor activity
AWC36_RS09900	COG5464	transposase or invertase
AWC36_RS09910	COG0531	amino acid
AWC36_RS09945	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AWC36_RS09960	COG1677	Flagellar hook-basal body complex protein FliE
AWC36_RS09965	COG1766	The M ring may be actively involved in energy transduction
AWC36_RS09975	COG1317	bacterial-type flagellum organization
AWC36_RS10030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AWC36_RS10045	COG1706	bacterial-type flagellum-dependent cell motility
AWC36_RS10050	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AWC36_RS10065	COG1749	Flagellar hook protein flgE
AWC36_RS10070	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AWC36_RS10075	COG1558	bacterial-type flagellum-dependent cell motility
AWC36_RS10080	COG1815	bacterial-type flagellum-dependent cell motility
AWC36_RS10090	COG2747	anti-sigma28 factor FlgM
AWC36_RS10095	COG3418	PFAM FlgN family protein
AWC36_RS10105	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AWC36_RS10110	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AWC36_RS10125	COG2201	protein-glutamate methylesterase activity
AWC36_RS10130	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AWC36_RS10135	COG0840	transmembrane signaling receptor activity
AWC36_RS10140	COG0835	chemotaxis
AWC36_RS10145	COG2198	Histidine kinase
AWC36_RS10145	COG0643	Histidine kinase
AWC36_RS10170	COG0840	transmembrane signaling receptor activity
AWC36_RS10180	COG3706	GGDEF domain
AWC36_RS10185	COG0840	transmembrane signaling receptor activity
AWC36_RS10190	COG4249	Peptidase C14 caspase catalytic subunit p20
AWC36_RS10215	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AWC36_RS10220	COG0322	excinuclease ABC activity
AWC36_RS10225	COG2197	response regulator
AWC36_RS10240	COG1113	amino acid transport
AWC36_RS10260	COG1802	Transcriptional regulator
AWC36_RS10270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWC36_RS10275	COG0601	transmembrane transport
AWC36_RS10305	COG0835	chemotaxis
AWC36_RS10305	COG0784	Response regulator, receiver
AWC36_RS10325	COG0765	amino acid transport
AWC36_RS10330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWC36_RS10345	COG1473	amidohydrolase
AWC36_RS10390	COG1882	Formate acetyltransferase
AWC36_RS10395	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AWC36_RS10400	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AWC36_RS10410	COG1349	DNA-binding transcription factor activity
AWC36_RS10420	COG1053	succinate dehydrogenase
AWC36_RS10420	COG0431	NADPH-dependent FMN reductase
AWC36_RS10420	COG3976	FMN-binding domain protein
AWC36_RS10425	COG0183	Belongs to the thiolase family
AWC36_RS10440	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AWC36_RS10445	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AWC36_RS10450	COG0183	Belongs to the thiolase family
AWC36_RS10455	COG3246	L-lysine catabolic process to acetate
AWC36_RS10465	COG0583	DNA-binding transcription factor activity
AWC36_RS10475	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWC36_RS10485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWC36_RS10495	COG1609	Transcriptional regulator
AWC36_RS10500	COG2207	Transcriptional regulator
AWC36_RS10505	COG1012	belongs to the aldehyde dehydrogenase family
AWC36_RS10510	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AWC36_RS10525	COG0154	amidase activity
AWC36_RS10530	COG4172	Belongs to the ABC transporter superfamily
AWC36_RS10535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWC36_RS10540	COG0601	transmembrane transport
AWC36_RS10545	COG0747	negative chemotaxis
AWC36_RS10555	COG2200	EAL domain
AWC36_RS10560	COG4993	Dehydrogenase
AWC36_RS10575	COG0402	S-adenosylhomocysteine deaminase activity
AWC36_RS10580	COG1126	abc transporter atp-binding protein
AWC36_RS10585	COG0765	amino acid transport
AWC36_RS10590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWC36_RS10600	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AWC36_RS10605	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWC36_RS10610	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AWC36_RS10615	COG4521	taurine ABC transporter
AWC36_RS10620	COG1177	transmembrane transport
AWC36_RS10625	COG1176	ABC-type spermidine putrescine transport system, permease component I
AWC36_RS10630	COG3842	ATPase activity
AWC36_RS10635	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AWC36_RS10650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWC36_RS10665	COG0583	DNA-binding transcription factor activity
AWC36_RS10680	COG0444	Belongs to the ABC transporter superfamily
AWC36_RS10695	COG0747	negative chemotaxis
AWC36_RS10700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWC36_RS10705	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AWC36_RS10715	COG0477	Major facilitator Superfamily
AWC36_RS10720	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AWC36_RS10730	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AWC36_RS10735	COG1012	belongs to the aldehyde dehydrogenase family
AWC36_RS10740	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AWC36_RS10750	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AWC36_RS10770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWC36_RS10780	COG1301	dicarboxylic acid transport
AWC36_RS10790	COG0679	Auxin Efflux Carrier
AWC36_RS10795	COG0697	spore germination
AWC36_RS10805	COG0577	efflux transmembrane transporter activity
AWC36_RS10805	COG1136	(ABC) transporter
AWC36_RS10815	COG1136	(ABC) transporter
AWC36_RS10815	COG0577	efflux transmembrane transporter activity
AWC36_RS10830	COG0672	)-iron permease
AWC36_RS10835	COG0298	carbon dioxide binding
AWC36_RS10845	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AWC36_RS10850	COG0651	ATP synthesis coupled electron transport
AWC36_RS10855	COG0650	Formate hydrogenlyase subunit 4
AWC36_RS10860	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AWC36_RS10865	COG4237	Hydrogenase 4 membrane
AWC36_RS10870	COG0651	ATP synthesis coupled electron transport
AWC36_RS10875	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AWC36_RS10875	COG3261	NADH dehydrogenase
AWC36_RS10880	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWC36_RS10885	COG3260	NADH ubiquinone oxidoreductase 20
AWC36_RS10895	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AWC36_RS10900	COG0840	transmembrane signaling receptor activity
AWC36_RS10905	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AWC36_RS10910	COG3383	formate dehydrogenase (NAD+) activity
AWC36_RS10920	COG1301	dicarboxylic acid transport
AWC36_RS10925	COG0583	DNA-binding transcription factor activity
AWC36_RS10945	COG2271	Major facilitator Superfamily
AWC36_RS10950	COG1840	ABC-type Fe3 transport system, periplasmic component
AWC36_RS10960	COG3842	ATPase activity
AWC36_RS10970	COG0662	Cupin 2, conserved barrel domain protein
AWC36_RS10970	COG2207	Transcriptional regulator
AWC36_RS11000	COG3135	benzoate transporter
AWC36_RS11015	COG0312	modulator of DNA gyrase
AWC36_RS11020	COG0312	modulator of DNA gyrase
AWC36_RS11025	COG3118	belongs to the thioredoxin family
AWC36_RS11030	COG4178	(ABC) transporter
AWC36_RS11045	COG3712	iron ion homeostasis
AWC36_RS11065	COG0583	DNA-binding transcription factor activity
AWC36_RS11080	COG0765	amino acid transport
AWC36_RS11090	COG1012	belongs to the aldehyde dehydrogenase family
AWC36_RS11100	COG4773	Receptor
AWC36_RS11105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWC36_RS11110	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWC36_RS11115	COG1120	ATPase activity
AWC36_RS11120	COG0113	porphobilinogen synthase activity
AWC36_RS11135	COG0531	amino acid
AWC36_RS11140	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AWC36_RS11145	COG0583	DNA-binding transcription factor activity
AWC36_RS11160	COG2814	Major facilitator Superfamily
AWC36_RS11170	COG2223	nitrite transmembrane transporter activity
AWC36_RS11175	COG2223	nitrite transmembrane transporter activity
AWC36_RS11190	COG2814	Major facilitator Superfamily
AWC36_RS11195	COG1378	Sugar-specific transcriptional regulator TrmB
AWC36_RS11200	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AWC36_RS11220	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AWC36_RS11225	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AWC36_RS11230	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AWC36_RS11235	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AWC36_RS11255	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AWC36_RS11270	COG0494	nUDIX hydrolase
AWC36_RS11275	COG1309	transcriptional regulator
AWC36_RS11280	COG0604	alcohol dehydrogenase
AWC36_RS11285	COG1473	amidohydrolase
AWC36_RS11295	COG0583	DNA-binding transcription factor activity
AWC36_RS11310	COG3539	Fimbrial protein
AWC36_RS11355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWC36_RS11355	COG1263	PTS System
AWC36_RS11380	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AWC36_RS11385	COG1053	succinate dehydrogenase
AWC36_RS11390	COG2271	Major facilitator Superfamily
AWC36_RS11400	COG0673	inositol 2-dehydrogenase activity
AWC36_RS11405	COG1028	Short-chain dehydrogenase reductase Sdr
AWC36_RS11425	COG0765	amino acid transport
AWC36_RS11430	COG0765	amino acid transport
AWC36_RS11440	COG0656	L-ascorbic acid biosynthetic process
AWC36_RS11445	COG2814	Major facilitator Superfamily
AWC36_RS11450	COG1013	pyruvate-flavodoxin oxidoreductase activity
AWC36_RS11455	COG0674	pyruvate-flavodoxin oxidoreductase activity
AWC36_RS11480	COG1402	creatininase
AWC36_RS11485	COG0840	transmembrane signaling receptor activity
AWC36_RS11490	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AWC36_RS11510	COG2076	Multidrug Resistance protein
AWC36_RS11515	COG1882	Formate acetyltransferase
AWC36_RS11520	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AWC36_RS11530	COG0628	permease
AWC36_RS11545	COG1280	lysine exporter protein (LysE YggA)
AWC36_RS11570	COG3842	ATPase activity
AWC36_RS11585	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AWC36_RS11595	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AWC36_RS11605	COG1492	cobalamin metabolic process
AWC36_RS11670	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
AWC36_RS11680	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AWC36_RS11690	COG1064	alcohol dehydrogenase
AWC36_RS11695	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AWC36_RS11715	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AWC36_RS11720	COG3842	ATPase activity
AWC36_RS11725	COG1176	ABC-type spermidine putrescine transport system, permease component I
AWC36_RS11730	COG1177	transmembrane transport
AWC36_RS11740	COG3711	transcriptional antiterminator
AWC36_RS11745	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AWC36_RS11770	COG3012	SEC-C Motif Domain Protein
AWC36_RS11775	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AWC36_RS11790	COG0586	Pfam SNARE associated Golgi protein
AWC36_RS11815	COG0438	transferase activity, transferring glycosyl groups
AWC36_RS11855	COG1088	dTDP-glucose 4,6-dehydratase activity
AWC36_RS11885	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AWC36_RS11890	COG1253	flavin adenine dinucleotide binding
AWC36_RS11900	COG5464	transposase or invertase
AWC36_RS11905	COG2982	Protein involved in outer membrane biogenesis
AWC36_RS11910	COG0717	Belongs to the dCTP deaminase family
AWC36_RS11915	COG0572	uridine kinase
AWC36_RS11925	COG0489	protein tyrosine kinase activity
AWC36_RS11930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWC36_RS11930	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWC36_RS11935	COG3383	formate dehydrogenase (NAD+) activity
AWC36_RS11935	COG0243	molybdopterin cofactor binding
AWC36_RS11940	COG0437	4 iron, 4 sulfur cluster binding
AWC36_RS11945	COG2864	formate dehydrogenase
AWC36_RS11960	COG2706	6-phosphogluconolactonase activity
AWC36_RS11965	COG0561	phosphatase activity
AWC36_RS11970	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AWC36_RS11975	COG4149	molybdate abc transporter
AWC36_RS11980	COG0725	ABC transporter, periplasmic molybdate-binding protein
AWC36_RS11990	COG3585	molybdate ion transport
AWC36_RS11990	COG2005	Transcriptional regulator
AWC36_RS11995	COG1119	ATPase activity
AWC36_RS12000	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AWC36_RS12005	COG2017	converts alpha-aldose to the beta-anomer
AWC36_RS12025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWC36_RS12030	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AWC36_RS12035	COG0588	phosphoglycerate mutase activity
AWC36_RS12040	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AWC36_RS12045	COG1230	cation diffusion facilitator family transporter
AWC36_RS12055	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AWC36_RS12065	COG1811	Na channel or pump
AWC36_RS12085	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AWC36_RS12090	COG2885	chlorophyll binding
AWC36_RS12095	COG0823	Involved in the tonB-independent uptake of proteins
AWC36_RS12100	COG3064	Membrane
AWC36_RS12100	COG3064	Membrane
AWC36_RS12105	COG0848	biopolymer transport protein
AWC36_RS12110	COG0811	peptide transport
AWC36_RS12115	COG0824	Thioesterase
AWC36_RS12120	COG3790	cyd operon protein YbgE
AWC36_RS12125	COG4890	Cyd operon protein YbgT
AWC36_RS12130	COG1294	oxidase, subunit
AWC36_RS12135	COG1271	oxidase subunit
AWC36_RS12140	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AWC36_RS12145	COG0045	succinate-CoA ligase (ADP-forming) activity
AWC36_RS12150	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWC36_RS12155	COG0567	Dehydrogenase, E1 component
AWC36_RS12160	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AWC36_RS12165	COG1053	succinate dehydrogenase
AWC36_RS12170	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AWC36_RS12180	COG0372	Belongs to the citrate synthase family
AWC36_RS12185	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AWC36_RS12190	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AWC36_RS12195	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AWC36_RS12200	COG1984	allophanate hydrolase subunit 2
AWC36_RS12205	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AWC36_RS12210	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AWC36_RS12220	COG3272	Protein of unknown function (DUF1722)
AWC36_RS12230	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AWC36_RS12235	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AWC36_RS12240	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AWC36_RS12245	COG2205	protein histidine kinase activity
AWC36_RS12250	COG0745	RESPONSE REGULATOR receiver
AWC36_RS12260	COG0033	Phosphoglucomutase
AWC36_RS12265	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AWC36_RS12270	COG0596	Alpha beta hydrolase
AWC36_RS12280	COG0840	transmembrane signaling receptor activity
AWC36_RS12290	COG0735	belongs to the Fur family
AWC36_RS12295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AWC36_RS12300	COG1263	PTS System
AWC36_RS12300	COG2190	(PTS) system
AWC36_RS12300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWC36_RS12305	COG0363	glucosamine-6-phosphate deaminase activity
AWC36_RS12310	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AWC36_RS12315	COG1846	Transcriptional regulator
AWC36_RS12315	COG1940	carbohydrate kinase activity
AWC36_RS12320	COG0367	asparagine synthase
AWC36_RS12360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AWC36_RS12365	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AWC36_RS12370	COG1702	phosphate starvation-inducible protein PhoH
AWC36_RS12375	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AWC36_RS12380	COG4535	Mg2 and Co2 transporter CorC
AWC36_RS12385	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AWC36_RS12395	COG0765	amino acid transport
AWC36_RS12400	COG0765	amino acid transport
AWC36_RS12405	COG1126	abc transporter atp-binding protein
AWC36_RS12415	COG3539	Fimbrial protein
AWC36_RS12430	COG3121	Chaperone
AWC36_RS12460	COG2888	peptidyl-tyrosine sulfation
AWC36_RS12465	COG0495	leucyl-tRNA aminoacylation
AWC36_RS12470	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
AWC36_RS12475	COG1466	dna polymerase III delta subunit
AWC36_RS12480	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AWC36_RS12485	COG0799	negative regulation of ribosome biogenesis
AWC36_RS12490	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AWC36_RS12495	COG0768	penicillin binding
AWC36_RS12500	COG0772	Belongs to the SEDS family
AWC36_RS12505	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AWC36_RS12510	COG1686	Belongs to the peptidase S11 family
AWC36_RS12520	COG0321	lipoyl(octanoyl) transferase activity
AWC36_RS12525	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AWC36_RS12530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AWC36_RS12535	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AWC36_RS12545	COG1794	racemase activity, acting on amino acids and derivatives
AWC36_RS12550	COG1393	Belongs to the ArsC family
AWC36_RS12555	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AWC36_RS12560	COG1876	peptidase activity
AWC36_RS12570	COG0400	carboxylic ester hydrolase activity
AWC36_RS12575	COG1444	tRNA N-acetyltransferase activity
AWC36_RS12580	COG2707	UPF0756 membrane protein
AWC36_RS12595	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AWC36_RS12600	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AWC36_RS12610	COG2716	regulation of RNA biosynthetic process
AWC36_RS12615	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AWC36_RS12625	COG4783	chaperone-mediated protein folding
AWC36_RS12630	COG1393	Belongs to the ArsC family
AWC36_RS12635	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AWC36_RS12640	COG2233	PERMEase
AWC36_RS12645	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AWC36_RS12650	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AWC36_RS12655	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AWC36_RS12675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWC36_RS12680	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AWC36_RS12685	COG4181	ATPase activity
AWC36_RS12690	COG2755	lipolytic protein G-D-S-L family
AWC36_RS12695	COG0300	oxidoreductase activity
AWC36_RS12700	COG3118	belongs to the thioredoxin family
AWC36_RS12725	COG1441	menaquinone biosynthetic process
AWC36_RS12730	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AWC36_RS12735	COG0596	Alpha beta hydrolase
AWC36_RS12740	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AWC36_RS12745	COG1169	isochorismate synthase
AWC36_RS12750	COG2223	nitrite transmembrane transporter activity
AWC36_RS12755	COG2198	Histidine kinase
AWC36_RS12755	COG0642	Histidine kinase
AWC36_RS12760	COG2197	response regulator
AWC36_RS12765	COG2205	protein histidine kinase activity
AWC36_RS12765	COG0784	Response regulator, receiver
AWC36_RS12785	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AWC36_RS12790	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AWC36_RS12795	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AWC36_RS12805	COG0154	amidase activity
AWC36_RS12810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWC36_RS12815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWC36_RS12820	COG1116	anion transmembrane transporter activity
AWC36_RS12825	COG0330	HflC and HflK could
AWC36_RS12830	COG1585	Membrane protein implicated in regulation of membrane protease activity
AWC36_RS12835	COG0183	Belongs to the thiolase family
AWC36_RS12840	COG2031	fatty acid transporter
AWC36_RS12845	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AWC36_RS12850	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AWC36_RS12855	COG2204	response regulator
AWC36_RS12860	COG3852	Histidine kinase
AWC36_RS12875	COG2217	Heavy metal translocating P-type atpase
AWC36_RS12880	COG3735	TraB family
AWC36_RS12885	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AWC36_RS12890	COG0523	cobalamin synthesis protein
AWC36_RS12895	COG2879	small protein
AWC36_RS12900	COG1966	Carbon starvation protein
AWC36_RS12915	COG0511	ligase activity, forming carbon-carbon bonds
AWC36_RS12920	COG0439	Biotin carboxylase
AWC36_RS12930	COG1984	allophanate hydrolase subunit 2
AWC36_RS12950	COG0737	Belongs to the 5'-nucleotidase family
AWC36_RS12960	COG4651	solute:proton antiporter activity
AWC36_RS12960	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AWC36_RS12965	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AWC36_RS12980	COG1215	transferase activity, transferring glycosyl groups
AWC36_RS12990	COG0489	protein tyrosine kinase activity
AWC36_RS13000	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AWC36_RS13005	COG0563	adenylate kinase activity
AWC36_RS13010	COG0326	Molecular chaperone. Has ATPase activity
AWC36_RS13015	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AWC36_RS13020	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AWC36_RS13025	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AWC36_RS13030	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AWC36_RS13035	COG2832	Protein of unknown function (DUF454)
AWC36_RS13050	COG1309	transcriptional regulator
AWC36_RS13055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWC36_RS13060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AWC36_RS13065	COG0254	rRNA binding
AWC36_RS13070	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AWC36_RS13090	COG3695	enzyme binding
AWC36_RS13095	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AWC36_RS13100	COG1946	Acyl-CoA thioesterase
AWC36_RS13105	COG0004	ammonium transporteR
AWC36_RS13110	COG0347	Belongs to the P(II) protein family
AWC36_RS13115	COG1132	(ABC) transporter
AWC36_RS13120	COG1132	(ABC) transporter
AWC36_RS13125	COG1522	sequence-specific DNA binding
AWC36_RS13130	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AWC36_RS13135	COG1555	photosystem II stabilization
AWC36_RS13140	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AWC36_RS13145	COG0776	regulation of translation
AWC36_RS13150	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AWC36_RS13155	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AWC36_RS13160	COG0740	serine-type endopeptidase activity
AWC36_RS13165	COG0544	peptidyl-prolyl cis-trans isomerase activity
AWC36_RS13170	COG0271	Belongs to the BolA IbaG family
AWC36_RS13175	COG3056	Lipoprotein
AWC36_RS13180	COG2223	nitrite transmembrane transporter activity
AWC36_RS13185	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AWC36_RS13190	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AWC36_RS13195	COG1845	cytochrome c oxidase, subunit III
AWC36_RS13200	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AWC36_RS13205	COG0109	protoheme IX farnesyltransferase activity
AWC36_RS13210	COG2814	Major facilitator Superfamily
AWC36_RS13215	COG1666	GTP binding
AWC36_RS13220	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AWC36_RS13225	COG0693	protein deglycase activity
AWC36_RS13230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AWC36_RS13230	COG0301	tRNA thio-modification
AWC36_RS13235	COG1722	exodeoxyribonuclease VII activity
AWC36_RS13240	COG0142	geranyltranstransferase activity
AWC36_RS13245	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AWC36_RS13265	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AWC36_RS13270	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AWC36_RS13275	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AWC36_RS13280	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AWC36_RS13285	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AWC36_RS13285	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AWC36_RS13290	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AWC36_RS13300	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AWC36_RS13305	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AWC36_RS13310	COG1862	Preprotein translocase
AWC36_RS13315	COG0343	queuine tRNA-ribosyltransferase activity
AWC36_RS13320	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AWC36_RS13325	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AWC36_RS13330	COG0450	alkyl hydroperoxide reductase
AWC36_RS13335	COG0668	transmembrane transport
AWC36_RS13355	COG5002	protein histidine kinase activity
AWC36_RS13365	COG0420	3'-5' exonuclease activity
AWC36_RS13370	COG0419	ATPase involved in DNA repair
AWC36_RS13375	COG2974	May be involved in recombination
AWC36_RS13385	COG3123	guanosine phosphorylase activity
AWC36_RS13390	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AWC36_RS13400	COG1312	Catalyzes the dehydration of D-mannonate
AWC36_RS13405	COG0246	Mannitol dehydrogenase
AWC36_RS13410	COG2186	Transcriptional regulator
AWC36_RS13440	COG2951	lytic endotransglycosylase activity
AWC36_RS13445	COG2824	Alkylphosphonate utilization operon protein PhnA
AWC36_RS13470	COG2079	MmgE PrpD family protein
AWC36_RS13475	COG4608	Belongs to the ABC transporter superfamily
AWC36_RS13480	COG0444	Belongs to the ABC transporter superfamily
AWC36_RS13485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWC36_RS13490	COG0601	transmembrane transport
AWC36_RS13495	COG0747	negative chemotaxis
AWC36_RS13500	COG1473	amidohydrolase
AWC36_RS13505	COG0583	DNA-binding transcription factor activity
AWC36_RS13580	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AWC36_RS13585	COG3015	lipoprotein NlpE involved in copper resistance
AWC36_RS13600	COG4568	rho-dependent transcription termination
AWC36_RS13605	COG0037	tRNA processing
AWC36_RS13610	COG0346	lactoylglutathione lyase activity
AWC36_RS13615	COG0825	malonyl-CoA metabolic process
AWC36_RS13620	COG0587	DNA-directed DNA polymerase activity
AWC36_RS13625	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AWC36_RS13630	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AWC36_RS13635	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AWC36_RS13640	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AWC36_RS13645	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AWC36_RS13650	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AWC36_RS13655	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AWC36_RS13660	COG0750	zinc metalloprotease
AWC36_RS13665	COG0575	Belongs to the CDS family
AWC36_RS13670	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AWC36_RS13675	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AWC36_RS13680	COG0233	cytoplasmic translational termination
AWC36_RS13685	COG0528	UMP kinase activity
AWC36_RS13690	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AWC36_RS13695	COG0052	Belongs to the universal ribosomal protein uS2 family
AWC36_RS13705	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AWC36_RS13740	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AWC36_RS13740	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AWC36_RS13745	COG1611	Belongs to the LOG family
AWC36_RS13750	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AWC36_RS13755	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AWC36_RS13760	COG2363	Small membrane protein
AWC36_RS13765	COG0583	DNA-binding transcription factor activity
AWC36_RS13780	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AWC36_RS13785	COG2166	iron-sulfur cluster assembly
AWC36_RS13790	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AWC36_RS13800	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AWC36_RS13815	COG0860	N-Acetylmuramoyl-L-alanine amidase
AWC36_RS13820	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AWC36_RS13820	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AWC36_RS13825	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AWC36_RS13830	COG1074	ATP-dependent DNA helicase activity
AWC36_RS13835	COG1025	Belongs to the peptidase M16 family
AWC36_RS13840	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AWC36_RS13855	COG4795	General secretion pathway protein
AWC36_RS13865	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AWC36_RS13870	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AWC36_RS13880	COG0494	nUDIX hydrolase
AWC36_RS13885	COG3066	DNA modification
AWC36_RS13890	COG0861	Integral membrane protein TerC family
AWC36_RS13900	COG0667	Aldo Keto reductase
AWC36_RS13905	COG0471	metal ion transport
AWC36_RS13910	COG2828	Protein conserved in bacteria
AWC36_RS13915	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AWC36_RS13920	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AWC36_RS13925	COG0583	DNA-binding transcription factor activity
AWC36_RS13935	COG3171	Protein conserved in bacteria
AWC36_RS13940	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AWC36_RS13950	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AWC36_RS13955	COG0741	lytic transglycosylase activity
AWC36_RS13970	COG5564	TIM-barrel signal transduction protein
AWC36_RS13975	COG5441	Belongs to the UPF0261 family
AWC36_RS13985	COG1309	transcriptional regulator
AWC36_RS14000	COG1113	amino acid transport
AWC36_RS14005	COG1982	Orn Lys Arg decarboxylase major
AWC36_RS14015	COG0582	viral genome integration into host DNA
AWC36_RS14040	COG2130	NADP-dependent
AWC36_RS14090	COG2076	Multidrug Resistance protein
AWC36_RS14095	COG2076	Multidrug Resistance protein
AWC36_RS14100	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AWC36_RS14105	COG0726	polysaccharide deacetylase
AWC36_RS14115	COG0463	Glycosyl transferase, family 2
AWC36_RS14135	COG5002	protein histidine kinase activity
AWC36_RS14145	COG0642	Histidine kinase
AWC36_RS14150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWC36_RS14160	COG2373	Large extracellular alpha-helical protein
AWC36_RS14175	COG0754	glutathionylspermidine amidase activity
AWC36_RS14180	COG0625	glutathione transferase activity
AWC36_RS14200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWC36_RS14215	COG0625	glutathione transferase activity
AWC36_RS14220	COG2223	nitrite transmembrane transporter activity
AWC36_RS14230	COG1609	Transcriptional regulator
AWC36_RS14235	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AWC36_RS14290	COG1802	Transcriptional regulator
AWC36_RS14295	COG0246	Mannitol dehydrogenase
AWC36_RS14300	COG0477	Major facilitator Superfamily
AWC36_RS14305	COG1063	alcohol dehydrogenase
AWC36_RS14310	COG4948	Mandelate Racemase Muconate Lactonizing
AWC36_RS14315	COG0437	4 iron, 4 sulfur cluster binding
AWC36_RS14320	COG3301	Polysulphide reductase, NrfD
AWC36_RS14325	COG0477	Major facilitator Superfamily
AWC36_RS14330	COG3145	DNA-N1-methyladenine dioxygenase activity
AWC36_RS14335	COG2169	Transcriptional regulator
AWC36_RS14335	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AWC36_RS14355	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AWC36_RS14355	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AWC36_RS14365	COG2188	Transcriptional regulator
AWC36_RS14370	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AWC36_RS14380	COG0601	transmembrane transport
AWC36_RS14385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWC36_RS14390	COG4172	Belongs to the ABC transporter superfamily
AWC36_RS14395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AWC36_RS14405	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AWC36_RS14415	COG0531	amino acid
AWC36_RS14420	COG3115	cell septum assembly
AWC36_RS14425	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AWC36_RS14430	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AWC36_RS14435	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWC36_RS14445	COG2190	(PTS) system
AWC36_RS14450	COG2205	protein histidine kinase activity
AWC36_RS14455	COG0745	RESPONSE REGULATOR receiver
AWC36_RS14460	COG1811	Na channel or pump
AWC36_RS14470	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AWC36_RS14475	COG0583	DNA-binding transcription factor activity
AWC36_RS14485	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AWC36_RS14490	COG0436	Aminotransferase
AWC36_RS14495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWC36_RS14505	COG0765	amino acid transport
AWC36_RS14510	COG1126	abc transporter atp-binding protein
AWC36_RS14515	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AWC36_RS14520	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AWC36_RS14525	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AWC36_RS14530	COG1028	Short-chain dehydrogenase reductase Sdr
AWC36_RS14540	COG2186	Transcriptional regulator
AWC36_RS14545	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AWC36_RS14550	COG2837	iron assimilation
AWC36_RS14570	COG0612	Peptidase, M16
AWC36_RS14575	COG4771	TonB-dependent receptor
AWC36_RS14585	COG0456	acetyltransferase
AWC36_RS14590	COG0408	coproporphyrinogen oxidase activity
AWC36_RS14595	COG1671	Belongs to the UPF0178 family
AWC36_RS14605	COG0494	nUDIX hydrolase
AWC36_RS14610	COG0583	DNA-binding transcription factor activity
AWC36_RS14625	COG1942	4-Oxalocrotonate Tautomerase
AWC36_RS14630	COG1914	H( )-stimulated, divalent metal cation uptake system
AWC36_RS14635	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AWC36_RS14640	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AWC36_RS14645	COG0497	DNA recombination
AWC36_RS14655	COG2914	Belongs to the UPF0125 (RnfH) family
AWC36_RS14660	COG2867	negative regulation of translational initiation
AWC36_RS14665	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AWC36_RS14675	COG0582	viral genome integration into host DNA
AWC36_RS14680	COG3423	Transcriptional regulator
AWC36_RS14690	COG1196	nuclear chromosome segregation
AWC36_RS14705	COG2026	Addiction module toxin, RelE StbE family
AWC36_RS14710	COG0582	viral genome integration into host DNA
AWC36_RS14720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWC36_RS14720	COG4191	Histidine kinase
AWC36_RS14750	COG1028	Short-chain dehydrogenase reductase Sdr
AWC36_RS14770	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AWC36_RS14780	COG0402	S-adenosylhomocysteine deaminase activity
AWC36_RS14785	COG1280	lysine exporter protein (LysE YggA)
AWC36_RS14820	COG0583	DNA-binding transcription factor activity
AWC36_RS14825	COG1013	pyruvate-flavodoxin oxidoreductase activity
AWC36_RS14825	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AWC36_RS14825	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWC36_RS14825	COG0674	pyruvate-flavodoxin oxidoreductase activity
AWC36_RS14855	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AWC36_RS14865	COG0765	amino acid transport
AWC36_RS14870	COG1126	abc transporter atp-binding protein
AWC36_RS14885	COG0765	amino acid transport
AWC36_RS14890	COG0765	amino acid transport
AWC36_RS14900	COG1126	abc transporter atp-binding protein
AWC36_RS14910	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AWC36_RS14920	COG0165	Argininosuccinate lyase
AWC36_RS14925	COG0840	transmembrane signaling receptor activity
AWC36_RS14930	COG1376	ErfK ybiS ycfS ynhG family protein
AWC36_RS14940	COG1566	PFAM secretion protein HlyD family protein
AWC36_RS14945	COG2814	Major facilitator Superfamily
AWC36_RS14965	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AWC36_RS14970	COG3162	membrane
AWC36_RS14975	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AWC36_RS14980	COG5464	transposase or invertase
AWC36_RS15060	COG4964	Belongs to the GSP D family
AWC36_RS15080	COG5002	protein histidine kinase activity
AWC36_RS15080	COG3850	Histidine kinase
AWC36_RS15090	COG0025	NhaP-type Na H and K H
AWC36_RS15095	COG2252	PERMEase
AWC36_RS15105	COG1560	Kdo2-lipid A biosynthetic process
AWC36_RS15110	COG1278	Cold shock
AWC36_RS15135	COG1105	Belongs to the carbohydrate kinase PfkB family
AWC36_RS15145	COG0484	heat shock protein binding
AWC36_RS15165	COG0395	ABC-type sugar transport system, permease component
AWC36_RS15200	COG3214	Protein conserved in bacteria
AWC36_RS15210	COG4771	TonB-dependent receptor
AWC36_RS15215	COG2819	hydrolase of the alpha beta superfamily
AWC36_RS15220	COG0251	oxidation-reduction process
AWC36_RS15225	COG0436	Aminotransferase
AWC36_RS15230	COG0439	Biotin carboxylase
AWC36_RS15260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWC36_RS15265	COG0601	transmembrane transport
AWC36_RS15270	COG0747	negative chemotaxis
AWC36_RS15275	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AWC36_RS15280	COG1984	allophanate hydrolase subunit 2
AWC36_RS15285	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AWC36_RS15310	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AWC36_RS15320	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AWC36_RS15325	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AWC36_RS15330	COG4974	Belongs to the 'phage' integrase family
AWC36_RS15335	COG0477	Major facilitator Superfamily
AWC36_RS15340	COG0716	FMN binding
AWC36_RS15345	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AWC36_RS15355	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AWC36_RS15360	COG0354	folic acid binding
AWC36_RS15365	COG1272	protein, Hemolysin III
AWC36_RS15375	COG1653	transport
AWC36_RS15380	COG3842	ATPase activity
AWC36_RS15385	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AWC36_RS15400	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AWC36_RS15400	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AWC36_RS15405	COG0509	glycine decarboxylation via glycine cleavage system
AWC36_RS15410	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AWC36_RS15455	COG0583	DNA-binding transcription factor activity
AWC36_RS15460	COG0667	Aldo Keto reductase
AWC36_RS15465	COG2813	Specifically methylates the guanine in position
AWC36_RS15470	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AWC36_RS15480	COG1595	DNA-templated transcription, initiation
AWC36_RS15495	COG4178	(ABC) transporter
AWC36_RS15500	COG0813	purine-nucleoside phosphorylase activity
AWC36_RS15505	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AWC36_RS15510	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AWC36_RS15520	COG1230	cation diffusion facilitator family transporter
AWC36_RS15530	COG2827	Endonuclease containing a URI domain
AWC36_RS15535	COG3153	acetyltransferase
AWC36_RS15540	COG3154	lipid carrier protein
AWC36_RS15545	COG0826	peptidase U32
AWC36_RS15550	COG0826	peptidase U32
AWC36_RS15570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWC36_RS15580	COG1609	Transcriptional regulator
AWC36_RS15585	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWC36_RS15595	COG3716	PTS system mannose fructose sorbose family IID component
AWC36_RS15605	COG0366	Alpha amylase catalytic
AWC36_RS15610	COG2194	sulfuric ester hydrolase activity
AWC36_RS15615	COG0513	Belongs to the DEAD box helicase family
AWC36_RS15625	COG1185	polyribonucleotide nucleotidyltransferase activity
AWC36_RS15630	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AWC36_RS15635	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AWC36_RS15640	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AWC36_RS15645	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AWC36_RS15650	COG0195	Participates in both transcription termination and antitermination
AWC36_RS15655	COG0779	Required for maturation of 30S ribosomal subunits
AWC36_RS15690	COG3706	GGDEF domain
AWC36_RS15705	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AWC36_RS15715	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AWC36_RS15720	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AWC36_RS15725	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWC36_RS15730	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AWC36_RS15735	COG1534	Rna-binding protein
AWC36_RS15745	COG2027	D-alanyl-D-alanine carboxypeptidase
AWC36_RS15750	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AWC36_RS15760	COG0697	spore germination
AWC36_RS15770	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AWC36_RS15775	COG0142	geranyltranstransferase activity
AWC36_RS15790	COG3423	Transcriptional regulator
AWC36_RS15795	COG0039	L-malate dehydrogenase activity
AWC36_RS15800	COG1438	arginine binding
AWC36_RS15805	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AWC36_RS15810	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AWC36_RS15815	COG0358	DNA primase activity
AWC36_RS15825	COG3663	DNA glycosylase
AWC36_RS15865	COG3678	ATP-independent chaperone mediated protein folding
AWC36_RS15875	COG2813	Specifically methylates the guanine in position
AWC36_RS15880	COG0673	inositol 2-dehydrogenase activity
AWC36_RS15885	COG0861	Integral membrane protein TerC family
AWC36_RS15890	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AWC36_RS15900	COG2721	sulfolactate sulfo-lyase activity
AWC36_RS15905	COG0246	Mannitol dehydrogenase
AWC36_RS15910	COG1904	glucuronate isomerase
AWC36_RS15915	COG2271	Major facilitator Superfamily
AWC36_RS15925	COG0586	Pfam SNARE associated Golgi protein
AWC36_RS15940	COG4575	ribosome binding
AWC36_RS15945	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AWC36_RS15955	COG2259	Doxx family
AWC36_RS15960	COG0435	Glutathione S-transferase
AWC36_RS15965	COG0583	DNA-binding transcription factor activity
AWC36_RS15970	COG1741	Belongs to the pirin family
AWC36_RS15975	COG0735	belongs to the Fur family
AWC36_RS15980	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AWC36_RS15985	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AWC36_RS15990	COG2937	Belongs to the GPAT DAPAT family
AWC36_RS15995	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AWC36_RS16000	COG3161	chorismate lyase activity
AWC36_RS16005	COG0459	protein refolding
AWC36_RS16010	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AWC36_RS16025	COG1324	tolerance protein
AWC36_RS16030	COG4232	protein-disulfide reductase activity
AWC36_RS16035	COG1309	transcriptional regulator
AWC36_RS16045	COG0582	viral genome integration into host DNA
AWC36_RS16125	COG2801	Transposase and inactivated derivatives
AWC36_RS16155	COG1566	PFAM secretion protein HlyD family protein
AWC36_RS16160	COG2814	Major facilitator Superfamily
AWC36_RS16210	COG1178	ABC-type Fe3 transport system permease component
AWC36_RS16215	COG1840	ABC-type Fe3 transport system, periplasmic component
AWC36_RS16220	COG3842	ATPase activity
AWC36_RS16235	COG0588	phosphoglycerate mutase activity
AWC36_RS16240	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AWC36_RS16250	COG0395	ABC-type sugar transport system, permease component
AWC36_RS16275	COG1175	transmembrane transport
AWC36_RS16280	COG1653	transport
AWC36_RS16285	COG1472	Belongs to the glycosyl hydrolase 3 family
AWC36_RS16290	COG1621	beta-fructofuranosidase activity
AWC36_RS16315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AWC36_RS16320	COG0084	hydrolase, TatD family'
AWC36_RS16330	COG5487	UPF0391 membrane protein
AWC36_RS16335	COG2823	Periplasmic or secreted lipoprotein
AWC36_RS16340	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AWC36_RS16350	COG3726	membrane protein affecting hemolysin expression
AWC36_RS16355	COG0560	Phosphoserine phosphatase
AWC36_RS16370	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AWC36_RS16380	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AWC36_RS16390	COG0006	proline dipeptidase activity
AWC36_RS16395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AWC36_RS16400	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AWC36_RS16410	COG1169	isochorismate synthase
AWC36_RS16415	COG2130	NADP-dependent
AWC36_RS16420	COG0531	amino acid
AWC36_RS16425	COG3477	response to acidic pH
AWC36_RS16430	COG0747	negative chemotaxis
AWC36_RS16440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWC36_RS16455	COG0444	Belongs to the ABC transporter superfamily
AWC36_RS16465	COG0601	transmembrane transport
AWC36_RS16470	COG0747	negative chemotaxis
AWC36_RS16505	COG3210	domain, Protein
AWC36_RS16510	COG2994	toxin metabolic process
AWC36_RS16515	COG2831	hemolysin activation secretion protein
AWC36_RS16520	COG0840	transmembrane signaling receptor activity
AWC36_RS16525	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AWC36_RS16530	COG0456	acetyltransferase
AWC36_RS16540	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AWC36_RS16545	COG2731	YhcH YjgK YiaL family protein
AWC36_RS16550	COG0540	Belongs to the ATCase OTCase family
AWC36_RS16555	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
AWC36_RS16560	COG0251	oxidation-reduction process
AWC36_RS16565	COG2308	Evidence 4 Homologs of previously reported genes of
AWC36_RS16585	COG4172	Belongs to the ABC transporter superfamily
AWC36_RS16590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWC36_RS16595	COG0601	transmembrane transport
AWC36_RS16605	COG1328	CTP reductase activity
AWC36_RS16610	COG0602	queuosine metabolic process
AWC36_RS16615	COG0702	epimerase
AWC36_RS16620	COG3787	Belongs to the UPF0306 family
AWC36_RS16660	COG0848	biopolymer transport protein
AWC36_RS16665	COG0811	peptide transport
AWC36_RS16670	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AWC36_RS16685	COG0525	valine-tRNA ligase activity
AWC36_RS16690	COG2927	DNA polymerase III (CHI subunit)
AWC36_RS16695	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AWC36_RS16700	COG0795	lipopolysaccharide-transporting ATPase activity
AWC36_RS16705	COG0795	lipopolysaccharide-transporting ATPase activity
AWC36_RS16720	COG0582	viral genome integration into host DNA
AWC36_RS16735	COG3550	peptidyl-serine autophosphorylation
AWC36_RS16785	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AWC36_RS16790	COG2226	methyltransferase
AWC36_RS16805	COG1346	cytolysis
AWC36_RS16820	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AWC36_RS16850	COG0583	DNA-binding transcription factor activity
AWC36_RS16860	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AWC36_RS16870	COG0586	Pfam SNARE associated Golgi protein
AWC36_RS16875	COG0656	L-ascorbic acid biosynthetic process
AWC36_RS16890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWC36_RS16895	COG2132	Multicopper oxidase
AWC36_RS16900	COG0204	Acyl-transferase
AWC36_RS16905	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AWC36_RS16915	COG2249	NAD(P)H dehydrogenase (quinone) activity
AWC36_RS16920	COG0583	DNA-binding transcription factor activity
AWC36_RS16930	COG3150	esterase
AWC36_RS16935	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AWC36_RS16940	COG3151	Protein conserved in bacteria
AWC36_RS16945	COG0494	nUDIX hydrolase
AWC36_RS16950	COG1538	Outer membrane efflux protein
AWC36_RS16955	COG5463	Belongs to the UPF0441 family
AWC36_RS16960	COG0754	glutathionylspermidine amidase activity
AWC36_RS16965	COG3384	dioxygenase
AWC36_RS16975	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AWC36_RS16980	COG3107	peptidoglycan biosynthetic process
AWC36_RS16985	COG0792	nuclease activity
AWC36_RS16990	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AWC36_RS16995	COG2823	Periplasmic or secreted lipoprotein
AWC36_RS17005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AWC36_RS17010	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AWC36_RS17015	COG5002	protein histidine kinase activity
AWC36_RS17015	COG2198	Histidine kinase
AWC36_RS17015	COG0784	Response regulator, receiver
AWC36_RS17020	COG1242	4 iron, 4 sulfur cluster binding
AWC36_RS17025	COG0069	glutamate synthase activity
AWC36_RS17025	COG0067	glutamate synthase
AWC36_RS17025	COG0070	glutamate synthase
AWC36_RS17030	COG0493	'glutamate synthase
AWC36_RS17035	COG2990	Protein conserved in bacteria
AWC36_RS17050	COG2969	positive regulation of protein catabolic process
AWC36_RS17055	COG0625	glutathione transferase activity
AWC36_RS17060	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AWC36_RS17065	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AWC36_RS17070	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AWC36_RS17075	COG3105	Protein conserved in bacteria
AWC36_RS17080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWC36_RS17085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWC36_RS17090	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AWC36_RS17095	COG5007	Belongs to the BolA IbaG family
AWC36_RS17100	COG3113	response to antibiotic
AWC36_RS17105	COG2854	intermembrane phospholipid transfer
AWC36_RS17110	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AWC36_RS17115	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AWC36_RS17120	COG1127	ABC transporter
AWC36_RS17125	COG0530	calcium, potassium:sodium antiporter activity
AWC36_RS17130	COG0517	IMP dehydrogenase activity
AWC36_RS17130	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AWC36_RS17135	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AWC36_RS17140	COG3117	lipopolysaccharide transmembrane transporter activity
AWC36_RS17145	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AWC36_RS17150	COG1137	ATPase activity
AWC36_RS17155	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AWC36_RS17165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWC36_RS17170	COG1660	Displays ATPase and GTPase activities
AWC36_RS17175	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWC36_RS17180	COG0312	modulator of DNA gyrase
AWC36_RS17185	COG3028	Belongs to the UPF0307 family
AWC36_RS17190	COG2202	Pas domain
AWC36_RS17190	COG2199	diguanylate cyclase activity
AWC36_RS17190	COG2200	EAL domain
AWC36_RS17195	COG0840	transmembrane signaling receptor activity
AWC36_RS17200	COG0312	modulator of DNA gyrase
AWC36_RS17205	COG3164	Protein of unknown function
AWC36_RS17210	COG1530	ribonuclease E activity
AWC36_RS17215	COG0424	maF-like protein
AWC36_RS17220	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AWC36_RS17225	COG1792	Involved in formation and maintenance of cell shape
AWC36_RS17230	COG1077	Cell shape determining protein MreB Mrl
AWC36_RS17235	COG2200	EAL domain
AWC36_RS17235	COG2199	diguanylate cyclase activity
AWC36_RS17240	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AWC36_RS17245	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AWC36_RS17250	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AWC36_RS17255	COG0511	ligase activity, forming carbon-carbon bonds
AWC36_RS17260	COG0439	Biotin carboxylase
AWC36_RS17265	COG3924	membrane
AWC36_RS17270	COG4145	pantothenate transmembrane transporter activity
AWC36_RS17275	COG2264	protein methyltransferase activity
AWC36_RS17290	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AWC36_RS17320	COG3730	PTS system glucitol sorbitol-specific
AWC36_RS17335	COG1028	Short-chain dehydrogenase reductase Sdr
AWC36_RS17340	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWC36_RS17345	COG1349	DNA-binding transcription factor activity
AWC36_RS17355	COG1609	Transcriptional regulator
AWC36_RS17370	COG0601	transmembrane transport
AWC36_RS17390	COG0251	oxidation-reduction process
AWC36_RS17395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWC36_RS17400	COG0765	amino acid transport
AWC36_RS17405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWC36_RS17410	COG4597	amino acid ABC transporter
AWC36_RS17415	COG0765	amino acid transport
AWC36_RS17420	COG1126	abc transporter atp-binding protein
AWC36_RS17460	COG0138	bifunctional purine biosynthesis protein purh
AWC36_RS17465	COG0151	Belongs to the GarS family
AWC36_RS17485	COG1515	deoxyribonuclease V activity
AWC36_RS17490	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AWC36_RS17495	COG2816	NAD+ diphosphatase activity
AWC36_RS17500	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AWC36_RS17505	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AWC36_RS17510	COG0352	thiamine-phosphate diphosphorylase activity
AWC36_RS17515	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AWC36_RS17520	COG2104	thiamine diphosphate biosynthetic process
AWC36_RS17525	COG2022	thiamine diphosphate biosynthetic process
AWC36_RS17535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWC36_RS17540	COG5457	Domain of unknown function (DUF1127)
AWC36_RS17545	COG0477	Major facilitator Superfamily
AWC36_RS17550	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AWC36_RS17555	COG0085	RNA polymerase activity
AWC36_RS17560	COG0222	ribosome binding
AWC36_RS17565	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AWC36_RS17580	COG0250	Participates in transcription elongation, termination and antitermination
AWC36_RS17590	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AWC36_RS17620	COG1072	(Pantothenic acid kinase))
AWC36_RS17625	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AWC36_RS17625	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AWC36_RS17630	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AWC36_RS17655	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AWC36_RS17665	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AWC36_RS17675	COG1309	transcriptional regulator
AWC36_RS17680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWC36_RS17700	COG0460	homoserine dehydrogenase
AWC36_RS17700	COG0527	aspartate kinase activity
AWC36_RS17705	COG0626	cystathionine gamma-synthase activity
AWC36_RS17710	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
AWC36_RS17720	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AWC36_RS17725	COG1609	Transcriptional regulator
AWC36_RS17730	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AWC36_RS17735	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AWC36_RS17740	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AWC36_RS17745	COG1575	Belongs to the MenA family. Type 1 subfamily
AWC36_RS17750	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AWC36_RS17755	COG3074	FtsZ-dependent cytokinesis
AWC36_RS17760	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AWC36_RS17775	COG1609	Transcriptional regulator
AWC36_RS17780	COG1494	fructose-1,6-bisphosphatase
AWC36_RS17790	COG3152	Membrane
AWC36_RS17800	COG0149	triose-phosphate isomerase activity
AWC36_RS17805	COG2957	Belongs to the agmatine deiminase family
AWC36_RS17810	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AWC36_RS17825	COG0205	6-phosphofructokinase activity
AWC36_RS17830	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AWC36_RS17835	COG2814	Major facilitator Superfamily
AWC36_RS17845	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AWC36_RS17850	COG0425	Belongs to the sulfur carrier protein TusA family
AWC36_RS17860	COG3714	YhhN family
AWC36_RS17875	COG3776	membrane
AWC36_RS17880	COG0742	ribosomal rna small subunit methyltransferase
AWC36_RS17885	COG0552	protein localization to endoplasmic reticulum
AWC36_RS17885	COG0552	protein localization to endoplasmic reticulum
AWC36_RS17890	COG2884	Cell division ATP-binding protein ftsE
AWC36_RS17895	COG2177	Part of the ABC transporter FtsEX involved in
AWC36_RS17915	COG0456	acetyltransferase
AWC36_RS17925	COG0559	Belongs to the binding-protein-dependent transport system permease family
AWC36_RS17930	COG4177	L-phenylalanine transmembrane transporter activity
AWC36_RS17935	COG0411	ABC transporter
AWC36_RS17940	COG0410	ABC transporter
AWC36_RS17955	COG2271	Major facilitator Superfamily
AWC36_RS17960	COG0235	Class ii aldolase
AWC36_RS17965	COG3395	kinase activity
AWC36_RS17970	COG1349	DNA-binding transcription factor activity
AWC36_RS17980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWC36_RS17985	COG0840	transmembrane signaling receptor activity
AWC36_RS17990	COG1653	transport
AWC36_RS17995	COG1175	transmembrane transport
AWC36_RS18000	COG0395	ABC-type sugar transport system, permease component
AWC36_RS18005	COG3842	ATPase activity
AWC36_RS18010	COG0584	glycerophosphoryl diester phosphodiesterase
AWC36_RS18025	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AWC36_RS18040	COG2205	protein histidine kinase activity
AWC36_RS18045	COG0745	RESPONSE REGULATOR receiver
AWC36_RS18050	COG3678	ATP-independent chaperone mediated protein folding
AWC36_RS18055	COG1598	PFAM Uncharacterised protein family UPF0150
AWC36_RS18065	COG1414	Transcriptional regulator
AWC36_RS18075	COG2731	YhcH YjgK YiaL family protein
AWC36_RS18090	COG1070	Carbohydrate kinase
AWC36_RS18095	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AWC36_RS18100	COG3623	hexulose-6-phosphate isomerase
AWC36_RS18105	COG0235	Class ii aldolase
AWC36_RS18110	COG1053	succinate dehydrogenase
AWC36_RS18115	COG0477	Major facilitator Superfamily
AWC36_RS18120	COG1295	ribonuclease BN
AWC36_RS18125	COG1942	4-Oxalocrotonate Tautomerase
AWC36_RS18130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWC36_RS18160	COG0612	Peptidase, M16
AWC36_RS18165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AWC36_RS18170	COG4172	Belongs to the ABC transporter superfamily
AWC36_RS18180	COG0601	transmembrane transport
AWC36_RS18185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWC36_RS18190	COG1301	dicarboxylic acid transport
AWC36_RS18195	COG2199	diguanylate cyclase activity
AWC36_RS18195	COG2200	EAL domain
AWC36_RS18225	COG1215	transferase activity, transferring glycosyl groups
AWC36_RS18230	COG1215	transferase activity, transferring glycosyl groups
AWC36_RS18235	COG0457	Tetratricopeptide repeat
AWC36_RS18235	COG3118	belongs to the thioredoxin family
AWC36_RS18240	COG2831	hemolysin activation secretion protein
AWC36_RS18270	COG1598	PFAM Uncharacterised protein family UPF0150
AWC36_RS18280	COG4608	Belongs to the ABC transporter superfamily
AWC36_RS18285	COG0444	Belongs to the ABC transporter superfamily
AWC36_RS18290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWC36_RS18295	COG0601	transmembrane transport
AWC36_RS18300	COG0747	negative chemotaxis
AWC36_RS18305	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AWC36_RS18335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWC36_RS18340	COG0765	amino acid transport
AWC36_RS18345	COG0765	amino acid transport
AWC36_RS18350	COG4598	ABC transporter
AWC36_RS18380	COG3845	ABC transporter
AWC36_RS18385	COG4603	Belongs to the binding-protein-dependent transport system permease family
AWC36_RS18390	COG1079	Belongs to the binding-protein-dependent transport system permease family
AWC36_RS18405	COG0697	spore germination
AWC36_RS18415	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AWC36_RS18420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWC36_RS18425	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AWC36_RS18435	COG2214	Heat shock protein DnaJ domain protein
AWC36_RS18440	COG0443	Heat shock 70 kDa protein
AWC36_RS18445	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AWC36_RS18455	COG0742	ribosomal rna small subunit methyltransferase
AWC36_RS18460	COG0589	response to stress
AWC36_RS18470	COG0306	phosphate transporter
AWC36_RS18475	COG2081	HI0933 family
AWC36_RS18480	COG2200	EAL domain
AWC36_RS18495	COG2197	response regulator
AWC36_RS18505	COG2271	Major facilitator Superfamily
AWC36_RS18510	COG2271	Major facilitator Superfamily
AWC36_RS18515	COG2194	sulfuric ester hydrolase activity
AWC36_RS18520	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AWC36_RS18530	COG0194	GDP metabolic process
AWC36_RS18535	COG1758	RNA polymerase activity
AWC36_RS18540	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AWC36_RS18545	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AWC36_RS18550	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AWC36_RS18555	COG2233	PERMEase
AWC36_RS18560	COG2982	Protein involved in outer membrane biogenesis
AWC36_RS18565	COG0456	acetyltransferase
AWC36_RS18570	COG1490	D-aminoacyl-tRNA deacylase activity
AWC36_RS18575	COG1011	Hydrolase
AWC36_RS18590	COG0174	glutamine synthetase
AWC36_RS18595	COG3852	Histidine kinase
AWC36_RS18610	COG3078	GTPase activator activity
AWC36_RS18620	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AWC36_RS18625	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AWC36_RS18625	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AWC36_RS18635	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AWC36_RS18640	COG3084	Protein conserved in bacteria
AWC36_RS18645	COG0746	molybdenum cofactor guanylyltransferase activity
AWC36_RS18650	COG1763	Mo-molybdopterin cofactor biosynthetic process
AWC36_RS18675	COG1609	Transcriptional regulator
AWC36_RS18680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWC36_RS18690	COG1172	Belongs to the binding-protein-dependent transport system permease family
AWC36_RS18695	COG1129	ABC transporter
AWC36_RS18700	COG1869	D-ribose catabolic process
AWC36_RS18705	COG3111	PFAM Bacterial OB fold (BOF) protein
AWC36_RS18720	COG3158	transport of potassium into the cell
AWC36_RS18725	COG0714	Associated with various cellular activities
AWC36_RS18730	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AWC36_RS18735	COG1522	sequence-specific DNA binding
AWC36_RS18740	COG0716	FMN binding
AWC36_RS18745	COG0445	tRNA wobble uridine modification
AWC36_RS18750	COG0357	Ribosomal RNA small subunit methyltransferase G
AWC36_RS18755	COG3312	ion transport
AWC36_RS18760	COG0356	it plays a direct role in the translocation of protons across the membrane
AWC36_RS18770	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AWC36_RS18775	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AWC36_RS18780	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AWC36_RS18785	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AWC36_RS18790	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AWC36_RS18795	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AWC36_RS18800	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AWC36_RS18805	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AWC36_RS18820	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AWC36_RS18825	COG0573	inorganic phosphate transmembrane transporter activity
AWC36_RS18830	COG0581	inorganic phosphate transmembrane transporter activity
AWC36_RS18835	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AWC36_RS18845	COG0747	negative chemotaxis
AWC36_RS18850	COG0601	transmembrane transport
AWC36_RS18855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWC36_RS18860	COG0444	Belongs to the ABC transporter superfamily
AWC36_RS18875	COG0583	DNA-binding transcription factor activity
AWC36_RS18885	COG1522	sequence-specific DNA binding
AWC36_RS18900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWC36_RS18905	COG0765	amino acid transport
AWC36_RS18910	COG0765	amino acid transport
AWC36_RS18915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AWC36_RS18960	COG2252	PERMEase
AWC36_RS18965	COG2091	lysine biosynthetic process via aminoadipic acid
AWC36_RS18975	COG1733	regulation of RNA biosynthetic process
AWC36_RS19000	COG1733	regulation of RNA biosynthetic process
AWC36_RS19005	COG0702	epimerase
AWC36_RS19010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWC36_RS19015	COG2222	sugar isomerase
AWC36_RS19025	COG2188	Transcriptional regulator
AWC36_RS19040	COG2423	ornithine cyclodeaminase activity
AWC36_RS19045	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AWC36_RS19045	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AWC36_RS19070	COG0789	Transcriptional regulator
AWC36_RS19075	COG1028	Short-chain dehydrogenase reductase Sdr
AWC36_RS19080	COG0583	DNA-binding transcription factor activity
AWC36_RS19085	COG0251	oxidation-reduction process
AWC36_RS19090	COG1028	Short-chain dehydrogenase reductase Sdr
AWC36_RS19095	COG0583	DNA-binding transcription factor activity
AWC36_RS19110	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AWC36_RS19115	COG0706	membrane insertase activity
AWC36_RS19125	COG0594	ribonuclease P activity
AWC36_RS19130	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AWC36_RS19140	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AWC36_RS19145	COG0592	DNA-directed DNA polymerase activity
AWC36_RS19150	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AWC36_RS19155	COG0187	DNA topoisomerase II activity
AWC36_RS19170	COG1609	Transcriptional regulator
AWC36_RS19180	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWC36_RS19185	COG1447	Phosphotransferase system cellobiose-specific component IIA
AWC36_RS19190	COG2723	6-phospho-beta-galactosidase activity
AWC36_RS19195	COG0561	phosphatase activity
AWC36_RS19210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AWC36_RS19225	COG0601	transmembrane transport
AWC36_RS19230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWC36_RS19240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWC36_RS19245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWC36_RS19250	COG2186	Transcriptional regulator
AWC36_RS19255	COG3734	2-keto-3-deoxy-galactonokinase
AWC36_RS19260	COG0800	Aldolase
AWC36_RS19265	COG4948	Mandelate Racemase Muconate Lactonizing
AWC36_RS19275	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWC36_RS19285	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AWC36_RS19290	COG1070	Carbohydrate kinase
AWC36_RS19295	COG1028	Short-chain dehydrogenase reductase Sdr
AWC36_RS19300	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWC36_RS19305	COG3775	system Galactitol-specific IIC component
AWC36_RS19315	COG0823	Involved in the tonB-independent uptake of proteins
AWC36_RS19320	COG5645	(Lipo)protein
AWC36_RS19325	COG0071	Belongs to the small heat shock protein (HSP20) family
AWC36_RS19330	COG0071	Belongs to the small heat shock protein (HSP20) family
AWC36_RS19335	COG0569	domain protein
AWC36_RS19335	COG2985	domain, Protein
AWC36_RS19340	COG0471	metal ion transport
AWC36_RS19345	COG3290	protein histidine kinase activity
AWC36_RS19350	COG4565	transcriptional regulatory protein
AWC36_RS19355	COG0837	glucose binding
AWC36_RS19360	COG3493	citrate carrier protein
AWC36_RS19365	COG0747	negative chemotaxis
AWC36_RS19370	COG0601	transmembrane transport
AWC36_RS19375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWC36_RS19380	COG0444	Belongs to the ABC transporter superfamily
AWC36_RS19385	COG4608	Belongs to the ABC transporter superfamily
AWC36_RS19390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWC36_RS19395	COG4221	oxidoreductase activity
AWC36_RS19400	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AWC36_RS19410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWC36_RS19415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWC36_RS19420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWC36_RS19430	COG0439	Biotin carboxylase
AWC36_RS19435	COG3665	Urea carboxylase-associated protein
AWC36_RS19445	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AWC36_RS19505	COG0165	Argininosuccinate lyase
AWC36_RS19515	COG0137	argininosuccinate synthase activity
AWC36_RS19525	COG3977	Valine--pyruvate aminotransferase
AWC36_RS19540	COG1609	Transcriptional regulator
AWC36_RS19555	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AWC36_RS19560	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWC36_RS19565	COG1397	ADP-ribosylglycohydrolase
AWC36_RS19570	COG0456	acetyltransferase
AWC36_RS19575	COG2818	Glycosylase
AWC36_RS19580	COG0730	response to heat
AWC36_RS19620	COG0751	glycine-tRNA ligase activity
AWC36_RS19635	COG2213	PTS system mannitol-specific
AWC36_RS19635	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWC36_RS19640	COG0246	Mannitol dehydrogenase
AWC36_RS19645	COG3722	fumarate hydratase activity
AWC36_RS19655	COG0840	transmembrane signaling receptor activity
AWC36_RS19660	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AWC36_RS19665	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AWC36_RS19670	COG1012	belongs to the aldehyde dehydrogenase family
AWC36_RS19675	COG3274	enterobacterial common antigen metabolic process
AWC36_RS19680	COG1070	Carbohydrate kinase
AWC36_RS19685	COG2115	Belongs to the xylose isomerase family
AWC36_RS19690	COG4213	ABC transporter substrate-binding protein
AWC36_RS19695	COG1129	ABC transporter
AWC36_RS19700	COG4214	carbohydrate transport
AWC36_RS19705	COG1609	Transcriptional regulator
AWC36_RS19705	COG2207	Transcriptional regulator
AWC36_RS19710	COG0693	protein deglycase activity
AWC36_RS19715	COG0137	argininosuccinate synthase activity
AWC36_RS19735	COG0601	transmembrane transport
AWC36_RS19740	COG0747	negative chemotaxis
AWC36_RS19745	COG0583	DNA-binding transcription factor activity
AWC36_RS19750	COG1126	abc transporter atp-binding protein
AWC36_RS19755	COG0165	Argininosuccinate lyase
AWC36_RS19760	COG0765	amino acid transport
AWC36_RS19765	COG0765	amino acid transport
AWC36_RS19770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWC36_RS19775	COG0583	DNA-binding transcription factor activity
AWC36_RS19785	COG1538	Outer membrane efflux protein
AWC36_RS19790	COG1566	PFAM secretion protein HlyD family protein
AWC36_RS19795	COG2814	Major facilitator Superfamily
AWC36_RS19840	COG3423	Transcriptional regulator
AWC36_RS19860	COG1561	YicC-like family, N-terminal region
AWC36_RS19865	COG0583	DNA-binding transcription factor activity
AWC36_RS19875	COG0747	negative chemotaxis
AWC36_RS19880	COG0601	transmembrane transport
AWC36_RS19885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWC36_RS19890	COG0444	Belongs to the ABC transporter superfamily
AWC36_RS19895	COG4608	Belongs to the ABC transporter superfamily
AWC36_RS19905	COG5464	transposase or invertase
AWC36_RS19910	COG1446	asparaginase
AWC36_RS19925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWC36_RS19930	COG0601	transmembrane transport
AWC36_RS19940	COG4172	Belongs to the ABC transporter superfamily
AWC36_RS19945	COG4948	Mandelate Racemase Muconate Lactonizing
AWC36_RS19950	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AWC36_RS19955	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AWC36_RS19960	COG1309	transcriptional regulator
AWC36_RS19965	COG0756	dUTP diphosphatase activity
AWC36_RS19970	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AWC36_RS19975	COG2003	Belongs to the UPF0758 family
AWC36_RS19980	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AWC36_RS19985	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AWC36_RS19990	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AWC36_RS19995	COG0859	PFAM glycosyl transferase family 9
AWC36_RS20000	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AWC36_RS20015	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AWC36_RS20020	COG1519	Transferase
AWC36_RS20025	COG1215	transferase activity, transferring glycosyl groups
AWC36_RS20045	COG0438	transferase activity, transferring glycosyl groups
AWC36_RS20050	COG0515	serine threonine protein kinase
AWC36_RS20055	COG0438	transferase activity, transferring glycosyl groups
AWC36_RS20060	COG0859	PFAM glycosyl transferase family 9
AWC36_RS20070	COG0859	PFAM glycosyl transferase family 9
AWC36_RS20080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWC36_RS20085	COG2861	carbohydrate metabolic process
AWC36_RS20090	COG4942	peptidase
AWC36_RS20095	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AWC36_RS20100	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AWC36_RS20105	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AWC36_RS20110	COG1045	serine acetyltransferase
AWC36_RS20125	COG0583	DNA-binding transcription factor activity
AWC36_RS20130	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AWC36_RS20135	COG0412	Dienelactone hydrolase
AWC36_RS20150	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AWC36_RS20155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AWC36_RS20165	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AWC36_RS20170	COG0165	Argininosuccinate lyase
AWC36_RS20175	COG1322	Protein conserved in bacteria
AWC36_RS20180	COG2226	methyltransferase
AWC36_RS20190	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AWC36_RS20195	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AWC36_RS20200	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AWC36_RS20205	COG0805	protein transport
AWC36_RS20210	COG0084	hydrolase, TatD family'
AWC36_RS20220	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AWC36_RS20230	COG0006	proline dipeptidase activity
AWC36_RS20235	COG1739	Uncharacterized protein family UPF0029
AWC36_RS20285	COG0583	DNA-binding transcription factor activity
AWC36_RS20290	COG3085	chromosome segregation
AWC36_RS20320	COG0129	dihydroxy-acid dehydratase activity
AWC36_RS20335	COG1525	nuclease
AWC36_RS20345	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AWC36_RS20350	COG0473	3-isopropylmalate dehydrogenase activity
AWC36_RS20355	COG0583	DNA-binding transcription factor activity
AWC36_RS20375	COG1126	abc transporter atp-binding protein
AWC36_RS20380	COG0765	amino acid transport
AWC36_RS20385	COG0765	amino acid transport
AWC36_RS20390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWC36_RS20400	COG0626	cystathionine gamma-synthase activity
AWC36_RS20405	COG2843	Capsule synthesis protein
AWC36_RS20420	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AWC36_RS20425	COG0210	DNA helicase
AWC36_RS20435	COG0248	Ppx GppA phosphatase
AWC36_RS20440	COG0513	Belongs to the DEAD box helicase family
AWC36_RS20445	COG3118	belongs to the thioredoxin family
AWC36_RS20455	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AWC36_RS20465	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AWC36_RS20470	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AWC36_RS20475	COG1088	dTDP-glucose 4,6-dehydratase activity
AWC36_RS20480	COG0456	acetyltransferase
AWC36_RS20485	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AWC36_RS20490	COG2244	polysaccharide biosynthetic process
AWC36_RS20495	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AWC36_RS20505	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AWC36_RS20535	COG1473	amidohydrolase
AWC36_RS20540	COG1126	abc transporter atp-binding protein
AWC36_RS20545	COG0765	amino acid transport
AWC36_RS20550	COG4597	amino acid ABC transporter
AWC36_RS20555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWC36_RS20575	COG1802	Transcriptional regulator
AWC36_RS20580	COG3071	HemY protein
AWC36_RS20585	COG2959	enzyme of heme biosynthesis
AWC36_RS20590	COG1587	Uroporphyrinogen-III synthase
AWC36_RS20595	COG0181	hydroxymethylbilane synthase activity
AWC36_RS20610	COG1965	Belongs to the frataxin family
AWC36_RS20620	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AWC36_RS20635	COG1011	Hydrolase
AWC36_RS20640	COG0210	DNA helicase
AWC36_RS20660	COG0598	Magnesium transport protein CorA
AWC36_RS20665	COG3180	Ammonia monooxygenase
AWC36_RS20675	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
AWC36_RS20680	COG0514	ATP-dependent DNA helicase (RecQ)
AWC36_RS20685	COG1280	lysine exporter protein (LysE YggA)
AWC36_RS20690	COG2267	carboxylic ester hydrolase activity
AWC36_RS20695	COG0561	phosphatase activity
AWC36_RS20700	COG2271	Major facilitator Superfamily
AWC36_RS20705	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AWC36_RS20710	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
AWC36_RS20715	COG0247	lactate metabolic process
AWC36_RS20720	COG1609	Transcriptional regulator
AWC36_RS20725	COG3265	gluconokinase activity
AWC36_RS20730	COG2610	gluconate transmembrane transporter activity
AWC36_RS20735	COG2095	MarC family integral membrane protein
AWC36_RS20745	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AWC36_RS20755	COG1073	alpha beta
AWC36_RS20755	COG2226	methyltransferase
AWC36_RS20760	COG0747	negative chemotaxis
AWC36_RS20765	COG0601	transmembrane transport
AWC36_RS20785	COG3275	phosphorelay sensor kinase activity
AWC36_RS20790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWC36_RS20800	COG4160	amino acid transport
AWC36_RS20815	COG0477	Major facilitator Superfamily
AWC36_RS20820	COG0583	DNA-binding transcription factor activity
AWC36_RS20825	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AWC36_RS20830	COG0830	nickel cation binding
AWC36_RS20835	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AWC36_RS20840	COG0804	urea catabolic process
AWC36_RS20855	COG0829	nickel cation binding
AWC36_RS20860	COG1126	abc transporter atp-binding protein
AWC36_RS20885	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AWC36_RS20890	COG1523	belongs to the glycosyl hydrolase 13 family
AWC36_RS20895	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AWC36_RS20900	COG0297	glycogen (starch) synthase activity
AWC36_RS20905	COG0058	SHG alpha-glucan phosphorylase activity
AWC36_RS20915	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AWC36_RS20920	COG0437	4 iron, 4 sulfur cluster binding
AWC36_RS20930	COG2414	aldehyde ferredoxin oxidoreductase
AWC36_RS20935	COG0437	4 iron, 4 sulfur cluster binding
AWC36_RS20940	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AWC36_RS20960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWC36_RS20985	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AWC36_RS20990	COG0705	Rhomboid family
AWC36_RS20995	COG1349	DNA-binding transcription factor activity
AWC36_RS21000	COG0058	SHG alpha-glucan phosphorylase activity
AWC36_RS21005	COG1640	4-alpha-glucanotransferase
AWC36_RS21010	COG1289	transmembrane transporter activity
AWC36_RS21015	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AWC36_RS21015	COG0316	Belongs to the HesB IscA family
AWC36_RS21020	COG1040	competence protein
AWC36_RS21025	COG2267	carboxylic ester hydrolase activity
AWC36_RS21030	COG1785	Belongs to the alkaline phosphatase family
AWC36_RS21060	COG2183	response to ionizing radiation
AWC36_RS21070	COG0028	Belongs to the TPP enzyme family
AWC36_RS21080	COG1854	S-ribosylhomocysteine lyase activity
AWC36_RS21085	COG2011	ABC-type metal ion transport system permease component
AWC36_RS21100	COG0436	Aminotransferase
AWC36_RS21110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AWC36_RS21115	COG0506	proline dehydrogenase activity
AWC36_RS21115	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AWC36_RS21115	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AWC36_RS21130	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AWC36_RS21135	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AWC36_RS21140	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AWC36_RS21145	COG1011	Hydrolase
AWC36_RS21155	COG0494	nUDIX hydrolase
AWC36_RS21160	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AWC36_RS21185	COG4796	Type ii and iii secretion system protein
AWC36_RS21190	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AWC36_RS21195	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AWC36_RS21210	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AWC36_RS21215	COG0546	phosphoglycolate phosphatase activity
AWC36_RS21225	COG1473	amidohydrolase
AWC36_RS21250	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AWC36_RS21250	COG1648	precorrin-2 dehydrogenase activity
AWC36_RS21255	COG4948	Mandelate Racemase Muconate Lactonizing
AWC36_RS21260	COG0747	negative chemotaxis
AWC36_RS21265	COG0601	transmembrane transport
AWC36_RS21270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWC36_RS21275	COG0444	Belongs to the ABC transporter superfamily
AWC36_RS21280	COG4608	Belongs to the ABC transporter superfamily
AWC36_RS21285	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AWC36_RS21290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWC36_RS21295	COG1765	OsmC-like protein
AWC36_RS21305	COG3954	Phosphoribulokinase
AWC36_RS21310	COG3089	Belongs to the UPF0270 family
AWC36_RS21315	COG0429	hydrolase of the alpha beta-hydrolase fold
AWC36_RS21325	COG0488	(ABC) transporter
AWC36_RS21330	COG2249	NAD(P)H dehydrogenase (quinone) activity
AWC36_RS21335	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AWC36_RS21335	COG0475	glutathione-regulated potassium exporter activity
AWC36_RS21340	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AWC36_RS21345	COG1047	Peptidyl-prolyl cis-trans
AWC36_RS21350	COG2900	Belongs to the SlyX family
AWC36_RS21355	COG0545	Peptidyl-prolyl cis-trans isomerase
AWC36_RS21360	COG2964	Protein conserved in bacteria
AWC36_RS21365	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AWC36_RS21370	COG2923	Belongs to the DsrF TusC family
AWC36_RS21375	COG2168	tRNA wobble position uridine thiolation
AWC36_RS21380	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AWC36_RS21385	COG0049	tRNA binding
AWC36_RS21395	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AWC36_RS21410	COG0051	transcription antitermination factor activity, RNA binding
AWC36_RS21415	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AWC36_RS21420	COG0088	Forms part of the polypeptide exit tunnel
AWC36_RS21425	COG0089	rRNA binding
AWC36_RS21430	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AWC36_RS21435	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AWC36_RS21445	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AWC36_RS21450	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AWC36_RS21460	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AWC36_RS21470	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AWC36_RS21475	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AWC36_RS21480	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AWC36_RS21485	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AWC36_RS21490	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AWC36_RS21500	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AWC36_RS21505	COG1841	ribosomal large subunit assembly
AWC36_RS21510	COG0200	Binds to the 23S rRNA
AWC36_RS21515	COG0201	protein transport
AWC36_RS21520	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AWC36_RS21525	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AWC36_RS21535	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AWC36_RS21540	COG0202	RNA polymerase activity
AWC36_RS21545	COG0203	ribosomal protein L17
AWC36_RS21555	COG3036	rescue of stalled ribosome
AWC36_RS21560	COG1970	mechanosensitive ion channel activity
AWC36_RS21565	COG0569	domain protein
AWC36_RS21570	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AWC36_RS21570	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AWC36_RS21575	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AWC36_RS21580	COG0242	peptide deformylase activity
AWC36_RS21585	COG0758	DNA mediated transformation
AWC36_RS21590	COG2922	Belongs to the Smg family
AWC36_RS21595	COG0551	DNA topoisomerase type I activity
AWC36_RS21600	COG0009	L-threonylcarbamoyladenylate synthase
AWC36_RS21605	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AWC36_RS21615	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AWC36_RS21650	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AWC36_RS21655	COG1410	methionine synthase
AWC36_RS21655	COG0646	methionine synthase
AWC36_RS21660	COG2207	Transcriptional regulator
AWC36_RS21670	COG0471	metal ion transport
AWC36_RS21695	COG1070	Carbohydrate kinase
AWC36_RS21710	COG0527	aspartate kinase activity
AWC36_RS21715	COG0166	Belongs to the GPI family
AWC36_RS21745	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AWC36_RS21750	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AWC36_RS21755	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AWC36_RS21760	COG1053	succinate dehydrogenase
AWC36_RS21765	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AWC36_RS21770	COG1511	domain protein
AWC36_RS21770	COG3264	Mechanosensitive ion channel
AWC36_RS21775	COG0688	phosphatidylethanolamine metabolic process
AWC36_RS21780	COG1162	GTPase activity
AWC36_RS21785	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AWC36_RS21795	COG0582	viral genome integration into host DNA
AWC36_RS21810	COG3423	Transcriptional regulator
AWC36_RS21825	COG0582	viral genome integration into host DNA
AWC36_RS21840	COG3423	Transcriptional regulator
AWC36_RS21875	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AWC36_RS21880	COG0149	triose-phosphate isomerase activity
AWC36_RS21890	COG1028	Short-chain dehydrogenase reductase Sdr
AWC36_RS21900	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AWC36_RS21910	COG0066	3-isopropylmalate dehydratase activity
AWC36_RS21920	COG0473	3-isopropylmalate dehydrogenase activity
AWC36_RS21940	COG3668	Plasmid stabilization system
AWC36_RS22005	COG0454	-acetyltransferase
AWC36_RS22020	COG0582	viral genome integration into host DNA
AWC36_RS22030	COG3433	isochorismatase activity
AWC36_RS22030	COG1535	isochorismatase
AWC36_RS22045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWC36_RS22045	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AWC36_RS22055	COG2994	toxin metabolic process
AWC36_RS22090	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AWC36_RS22095	COG0028	Belongs to the TPP enzyme family
AWC36_RS22100	COG1609	Transcriptional regulator
AWC36_RS22105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWC36_RS22105	COG1263	PTS System
AWC36_RS22110	COG2723	6-phospho-beta-galactosidase activity
AWC36_RS22120	COG0640	Transcriptional regulator
AWC36_RS22130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AWC36_RS22145	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWC36_RS22165	COG0205	6-phosphofructokinase activity
AWC36_RS22180	COG0366	Alpha amylase catalytic
AWC36_RS22185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AWC36_RS22195	COG1021	2,3-dihydroxybenzoate-AMP ligase
AWC36_RS22215	COG3433	isochorismatase activity
AWC36_RS22215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWC36_RS22215	COG2226	methyltransferase
AWC36_RS22250	COG2814	Major facilitator Superfamily
AWC36_RS22255	COG2375	cellular response to nickel ion
AWC36_RS22255	COG1132	(ABC) transporter
AWC36_RS22265	COG4771	TonB-dependent receptor
AWC36_RS22275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWC36_RS22280	COG3122	Protein conserved in bacteria
AWC36_RS22290	COG0697	spore germination
AWC36_RS22315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AWC36_RS22320	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AWC36_RS22335	COG0583	DNA-binding transcription factor activity
AWC36_RS22345	COG3634	alkyl hydroperoxide reductase activity
AWC36_RS22350	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AWC36_RS22355	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AWC36_RS22355	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AWC36_RS22360	COG0802	atpase or kinase
AWC36_RS22370	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AWC36_RS22375	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AWC36_RS22385	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AWC36_RS22390	COG0330	HflC and HflK could
AWC36_RS22395	COG0330	HflC and HflK could
AWC36_RS22400	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AWC36_RS22405	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AWC36_RS22410	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AWC36_RS22415	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AWC36_RS22420	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AWC36_RS22425	COG1678	Uncharacterized ACR, COG1678
AWC36_RS22430	COG0189	ligase activity
AWC36_RS22435	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AWC36_RS22440	COG2356	endonuclease I
AWC36_RS22445	COG3091	SprT-like family
AWC36_RS22450	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AWC36_RS22455	COG1166	arginine decarboxylase activity
AWC36_RS22465	COG0501	Belongs to the peptidase M48B family
AWC36_RS22470	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AWC36_RS22485	COG3842	ATPase activity
AWC36_RS22490	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AWC36_RS22495	COG0126	phosphoglycerate kinase activity
AWC36_RS22510	COG1279	arginine transmembrane transporter activity
AWC36_RS22520	COG0583	DNA-binding transcription factor activity
AWC36_RS22530	COG5301	cellulose 1,4-beta-cellobiosidase activity
AWC36_RS22535	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AWC36_RS22540	COG5301	cellulose 1,4-beta-cellobiosidase activity
AWC36_RS22550	COG3299	homolog of phage Mu protein gp47
AWC36_RS22560	COG4384	Bacteriophage Mu Gp45 protein
AWC36_RS22580	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
AWC36_RS22590	COG4386	tail sheath protein
AWC36_RS22620	COG4397	Mu-like prophage major head subunit gpT
AWC36_RS22650	COG4373	Mu-like prophage FluMu protein gp28
AWC36_RS22660	COG0640	Transcriptional regulator
AWC36_RS22740	COG2842	Transposition protein
AWC36_RS22745	COG2801	Transposase and inactivated derivatives
AWC36_RS22750	COG3423	Transcriptional regulator
AWC36_RS22760	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AWC36_RS22765	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AWC36_RS22770	COG0604	alcohol dehydrogenase
AWC36_RS22775	COG0488	(ABC) transporter
AWC36_RS22780	COG0741	lytic transglycosylase activity
AWC36_RS22785	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
AWC36_RS22790	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AWC36_RS22800	COG2207	Transcriptional regulator
AWC36_RS22800	COG3708	Transcriptional regulator
AWC36_RS22805	COG3045	CreA protein
AWC36_RS22810	COG0745	RESPONSE REGULATOR receiver
AWC36_RS22815	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AWC36_RS22830	COG0083	homoserine kinase activity
AWC36_RS22840	COG3022	response to hydroperoxide
AWC36_RS22845	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AWC36_RS22850	COG3706	GGDEF domain
AWC36_RS22855	COG0521	Mo-molybdopterin cofactor biosynthetic process
AWC36_RS22865	COG1584	GPR1 FUN34 yaaH family protein
AWC36_RS22870	COG0443	Heat shock 70 kDa protein
AWC36_RS22875	COG0484	heat shock protein binding
AWC36_RS22880	COG0268	Binds directly to 16S ribosomal RNA
AWC36_RS22885	COG0196	riboflavin kinase activity
AWC36_RS22890	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AWC36_RS22895	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AWC36_RS22900	COG1047	Peptidyl-prolyl cis-trans
AWC36_RS22905	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AWC36_RS22910	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AWC36_RS22915	COG0505	Belongs to the CarA family
AWC36_RS22925	COG1028	Short-chain dehydrogenase reductase Sdr
AWC36_RS22935	COG2966	Psort location CytoplasmicMembrane, score
AWC36_RS22940	COG3610	response to peptide
AWC36_RS22950	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AWC36_RS22955	COG2967	ApaG domain
AWC36_RS22960	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AWC36_RS22965	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AWC36_RS22970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AWC36_RS22975	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AWC36_RS22980	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AWC36_RS22985	COG0564	pseudouridine synthase activity
AWC36_RS22990	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AWC36_RS22995	COG0417	DNA replication proofreading
AWC36_RS23030	COG0586	Pfam SNARE associated Golgi protein
AWC36_RS23040	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AWC36_RS23045	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AWC36_RS23050	COG2986	histidine ammonia-lyase
AWC36_RS23075	COG1228	amidohydrolase
AWC36_RS23080	COG0440	acetolactate synthase activity
AWC36_RS23085	COG0028	Belongs to the TPP enzyme family
AWC36_RS23105	COG1053	succinate dehydrogenase
AWC36_RS23110	COG2009	succinate dehydrogenase
AWC36_RS23130	COG1454	alcohol dehydrogenase
AWC36_RS23130	COG1012	belongs to the aldehyde dehydrogenase family
AWC36_RS23135	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AWC36_RS23140	COG1178	ABC-type Fe3 transport system permease component
AWC36_RS23145	COG4143	(ABC) transporter
AWC36_RS23150	COG4533	DNA binding
AWC36_RS23165	COG3639	organic phosphonate transmembrane transporter activity
AWC36_RS23170	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AWC36_RS23185	COG0066	3-isopropylmalate dehydratase activity
AWC36_RS23190	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AWC36_RS23195	COG0473	3-isopropylmalate dehydrogenase activity
AWC36_RS23200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AWC36_RS23205	COG0028	Belongs to the TPP enzyme family
AWC36_RS23220	COG1609	Transcriptional regulator
AWC36_RS23230	COG0242	peptide deformylase activity
AWC36_RS23245	COG0275	rRNA processing
AWC36_RS23250	COG3116	cell division
AWC36_RS23255	COG0768	penicillin binding
AWC36_RS23260	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AWC36_RS23265	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AWC36_RS23270	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AWC36_RS23275	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AWC36_RS23280	COG0772	Belongs to the SEDS family
AWC36_RS23285	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AWC36_RS23290	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AWC36_RS23295	COG1181	Belongs to the D-alanine--D-alanine ligase family
AWC36_RS23300	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AWC36_RS23305	COG0849	cell division
AWC36_RS23310	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AWC36_RS23315	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AWC36_RS23330	COG0653	protein targeting
AWC36_RS23335	COG0494	nUDIX hydrolase
AWC36_RS23340	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AWC36_RS23345	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AWC36_RS23350	COG0237	dephospho-CoA kinase activity
AWC36_RS23360	COG0516	GMP reductase activity
AWC36_RS23365	COG1459	type II secretion system
AWC36_RS23370	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AWC36_RS23375	COG4969	Belongs to the N-Me-Phe pilin family
AWC36_RS23385	COG3023	N-Acetylmuramoyl-L-alanine amidase
AWC36_RS23390	COG3725	Membrane protein required for beta-lactamase induction
AWC36_RS23420	COG1113	amino acid transport
AWC36_RS23435	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AWC36_RS23440	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWC36_RS23445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWC36_RS23460	COG4771	TonB-dependent receptor
AWC36_RS23470	COG0840	transmembrane signaling receptor activity
AWC36_RS23480	COG1902	pentaerythritol trinitrate reductase activity
AWC36_RS23485	COG1120	ATPase activity
AWC36_RS23490	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWC36_RS23495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWC36_RS23500	COG4592	Periplasmic binding protein
AWC36_RS23505	COG5464	transposase or invertase
AWC36_RS23515	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AWC36_RS23520	COG0022	dehydrogenase e1 component
AWC36_RS23525	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWC36_RS23530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWC36_RS23535	COG3112	Uncharacterised protein family (UPF0231)
AWC36_RS23540	COG2271	Major facilitator Superfamily
AWC36_RS23545	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWC36_RS23550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AWC36_RS23555	COG1454	alcohol dehydrogenase
AWC36_RS23560	COG3395	kinase activity
AWC36_RS23565	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AWC36_RS23570	COG1349	DNA-binding transcription factor activity
AWC36_RS23575	COG0803	Belongs to the bacterial solute-binding protein 9 family
AWC36_RS23580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AWC36_RS23585	COG1121	(ABC) transporter
AWC36_RS23600	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AWC36_RS23605	COG0432	Pfam Uncharacterised protein family UPF0047
AWC36_RS23610	COG0840	transmembrane signaling receptor activity
AWC36_RS23615	COG3265	gluconokinase activity
AWC36_RS23620	COG2610	gluconate transmembrane transporter activity
AWC36_RS23625	COG0129	dihydroxy-acid dehydratase activity
AWC36_RS23630	COG1448	Aminotransferase
AWC36_RS23640	COG1522	sequence-specific DNA binding
AWC36_RS23645	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AWC36_RS23670	COG1280	lysine exporter protein (LysE YggA)
AWC36_RS23680	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AWC36_RS23780	COG1403	HNH endonuclease
AWC36_RS23795	COG3093	addiction module antidote protein HigA
AWC36_RS23835	COG4626	Terminase
AWC36_RS23835	COG1802	Transcriptional regulator
AWC36_RS23845	COG4695	Portal protein