locus-tag	class	description
EH206_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EH206_RS00010	COG0592	DNA-directed DNA polymerase activity
EH206_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EH206_RS00030	COG1609	Transcriptional regulator
EH206_RS00040	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EH206_RS00045	COG1447	Phosphotransferase system cellobiose-specific component IIA
EH206_RS00050	COG2723	6-phospho-beta-galactosidase activity
EH206_RS00055	COG0561	phosphatase activity
EH206_RS00065	COG0747	negative chemotaxis
EH206_RS00070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EH206_RS00075	COG1957	nucleoside hydrolase
EH206_RS00085	COG0601	transmembrane transport
EH206_RS00090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH206_RS00105	COG2186	Transcriptional regulator
EH206_RS00110	COG3734	2-keto-3-deoxy-galactonokinase
EH206_RS00115	COG0800	Aldolase
EH206_RS00120	COG4948	Mandelate Racemase Muconate Lactonizing
EH206_RS00125	COG2271	Major facilitator Superfamily
EH206_RS00130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EH206_RS00135	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH206_RS00145	COG4178	(ABC) transporter
EH206_RS00155	COG2217	Heavy metal translocating P-type atpase
EH206_RS00165	COG1937	Protein conserved in bacteria
EH206_RS00175	COG0823	Involved in the tonB-independent uptake of proteins
EH206_RS00200	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EH206_RS00210	COG2186	Transcriptional regulator
EH206_RS00240	COG5645	(Lipo)protein
EH206_RS00245	COG0071	Belongs to the small heat shock protein (HSP20) family
EH206_RS00250	COG0071	Belongs to the small heat shock protein (HSP20) family
EH206_RS00260	COG2985	domain, Protein
EH206_RS00260	COG0569	domain protein
EH206_RS00265	COG0471	metal ion transport
EH206_RS00270	COG3290	protein histidine kinase activity
EH206_RS00275	COG4565	transcriptional regulatory protein
EH206_RS00285	COG3493	citrate carrier protein
EH206_RS00290	COG0747	negative chemotaxis
EH206_RS00295	COG0601	transmembrane transport
EH206_RS00300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH206_RS00305	COG0444	Belongs to the ABC transporter superfamily
EH206_RS00310	COG4608	Belongs to the ABC transporter superfamily
EH206_RS00320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EH206_RS00325	COG4221	oxidoreductase activity
EH206_RS00330	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EH206_RS00340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH206_RS00345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH206_RS00350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH206_RS00355	COG4770	biotin carboxylase activity
EH206_RS00365	COG3665	Urea carboxylase-associated protein
EH206_RS00370	COG1116	anion transmembrane transporter activity
EH206_RS00410	COG3977	Valine--pyruvate aminotransferase
EH206_RS00435	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EH206_RS00440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EH206_RS00445	COG1397	ADP-ribosylglycohydrolase
EH206_RS00455	COG2818	Glycosylase
EH206_RS00460	COG0730	response to heat
EH206_RS00465	COG0752	glycyl-tRNA synthetase alpha subunit
EH206_RS00470	COG0751	glycine-tRNA ligase activity
EH206_RS00485	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EH206_RS00505	COG2213	PTS system mannitol-specific
EH206_RS00505	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH206_RS00510	COG0246	Mannitol dehydrogenase
EH206_RS00515	COG3722	fumarate hydratase activity
EH206_RS00530	COG0840	transmembrane signaling receptor activity
EH206_RS00535	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EH206_RS00540	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EH206_RS00545	COG1012	belongs to the aldehyde dehydrogenase family
EH206_RS00550	COG3274	enterobacterial common antigen metabolic process
EH206_RS00560	COG1070	Carbohydrate kinase
EH206_RS00565	COG2115	Belongs to the xylose isomerase family
EH206_RS00570	COG4213	ABC transporter substrate-binding protein
EH206_RS00575	COG1129	ABC transporter
EH206_RS00580	COG4214	carbohydrate transport
EH206_RS00585	COG2207	Transcriptional regulator
EH206_RS00585	COG1609	Transcriptional regulator
EH206_RS00595	COG0137	argininosuccinate synthase activity
EH206_RS00605	COG5464	transposase or invertase
EH206_RS00620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH206_RS00625	COG0601	transmembrane transport
EH206_RS00630	COG0747	negative chemotaxis
EH206_RS00635	COG0583	DNA-binding transcription factor activity
EH206_RS00650	COG3550	peptidyl-serine autophosphorylation
EH206_RS00675	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
EH206_RS00715	COG1396	sequence-specific DNA binding
EH206_RS00730	COG1561	YicC-like family, N-terminal region
EH206_RS00735	COG0583	DNA-binding transcription factor activity
EH206_RS00740	COG1446	asparaginase
EH206_RS00755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH206_RS00760	COG0601	transmembrane transport
EH206_RS00765	COG0747	negative chemotaxis
EH206_RS00770	COG4172	Belongs to the ABC transporter superfamily
EH206_RS00775	COG4948	Mandelate Racemase Muconate Lactonizing
EH206_RS00785	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EH206_RS00790	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EH206_RS00795	COG1309	transcriptional regulator
EH206_RS00800	COG0756	dUTP diphosphatase activity
EH206_RS00805	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EH206_RS00810	COG2003	Belongs to the UPF0758 family
EH206_RS00820	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EH206_RS00825	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EH206_RS00830	COG0859	PFAM glycosyl transferase family 9
EH206_RS00835	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EH206_RS00840	COG1519	Transferase
EH206_RS00865	COG3550	peptidyl-serine autophosphorylation
EH206_RS00875	COG5499	transcription regulator containing HTH domain
EH206_RS00880	COG4680	protein conserved in bacteria
EH206_RS00885	COG1304	FMN binding
EH206_RS00890	COG1012	belongs to the aldehyde dehydrogenase family
EH206_RS00895	COG2002	toxin-antitoxin pair type II binding
EH206_RS00910	COG4115	mRNA cleavage
EH206_RS00915	COG0463	Glycosyl transferase, family 2
EH206_RS00935	COG0515	serine threonine protein kinase
EH206_RS00940	COG0438	transferase activity, transferring glycosyl groups
EH206_RS00945	COG0859	PFAM glycosyl transferase family 9
EH206_RS00950	COG3307	-O-antigen
EH206_RS00955	COG0859	PFAM glycosyl transferase family 9
EH206_RS00965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EH206_RS00970	COG2861	carbohydrate metabolic process
EH206_RS00975	COG4942	peptidase
EH206_RS00980	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EH206_RS00985	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EH206_RS00990	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EH206_RS00995	COG1045	serine acetyltransferase
EH206_RS01010	COG0583	DNA-binding transcription factor activity
EH206_RS01015	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EH206_RS01020	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
EH206_RS01030	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EH206_RS01040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EH206_RS01045	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EH206_RS01050	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EH206_RS01055	COG0165	Argininosuccinate lyase
EH206_RS01060	COG1322	Protein conserved in bacteria
EH206_RS01065	COG2226	methyltransferase
EH206_RS01075	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EH206_RS01085	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EH206_RS01090	COG0805	protein transport
EH206_RS01095	COG0084	hydrolase, TatD family'
EH206_RS01110	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EH206_RS01120	COG0183	Belongs to the thiolase family
EH206_RS01125	COG1024	Enoyl-CoA hydratase
EH206_RS01125	COG1250	3-hydroxyacyl-CoA dehydrogenase
EH206_RS01130	COG0006	proline dipeptidase activity
EH206_RS01135	COG1739	Uncharacterized protein family UPF0029
EH206_RS01185	COG0583	DNA-binding transcription factor activity
EH206_RS01190	COG3085	chromosome segregation
EH206_RS01195	COG0606	chelatase, subunit chli
EH206_RS01210	COG3978	acetolactate synthase activity
EH206_RS01220	COG0129	dihydroxy-acid dehydratase activity
EH206_RS01235	COG1525	nuclease
EH206_RS01245	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EH206_RS01250	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EH206_RS01255	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EH206_RS01255	COG0506	proline dehydrogenase activity
EH206_RS01255	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EH206_RS01270	COG0248	Ppx GppA phosphatase
EH206_RS01275	COG0513	Belongs to the DEAD box helicase family
EH206_RS01280	COG3118	belongs to the thioredoxin family
EH206_RS01285	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EH206_RS01290	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EH206_RS01300	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EH206_RS01305	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EH206_RS01310	COG1088	dTDP-glucose 4,6-dehydratase activity
EH206_RS01315	COG0456	acetyltransferase
EH206_RS01320	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EH206_RS01325	COG2244	polysaccharide biosynthetic process
EH206_RS01330	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EH206_RS01340	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EH206_RS01380	COG4774	siderophore transport
EH206_RS01390	COG0456	acetyltransferase
EH206_RS01395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH206_RS01400	COG0765	amino acid transport
EH206_RS01405	COG1126	abc transporter atp-binding protein
EH206_RS01410	COG1473	amidohydrolase
EH206_RS01430	COG3071	HemY protein
EH206_RS01435	COG2959	enzyme of heme biosynthesis
EH206_RS01440	COG1587	Uroporphyrinogen-III synthase
EH206_RS01445	COG0181	hydroxymethylbilane synthase activity
EH206_RS01460	COG1965	Belongs to the frataxin family
EH206_RS01470	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EH206_RS01485	COG1011	Hydrolase
EH206_RS01490	COG0210	DNA helicase
EH206_RS01495	COG0598	Magnesium transport protein CorA
EH206_RS01500	COG3180	Ammonia monooxygenase
EH206_RS01515	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
EH206_RS01520	COG0514	ATP-dependent DNA helicase (RecQ)
EH206_RS01525	COG1280	lysine exporter protein (LysE YggA)
EH206_RS01530	COG2267	carboxylic ester hydrolase activity
EH206_RS01535	COG0561	phosphatase activity
EH206_RS01540	COG2271	Major facilitator Superfamily
EH206_RS01545	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EH206_RS01550	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EH206_RS01555	COG0247	lactate metabolic process
EH206_RS01560	COG1741	Belongs to the pirin family
EH206_RS01565	COG1609	Transcriptional regulator
EH206_RS01570	COG3265	gluconokinase activity
EH206_RS01575	COG2610	gluconate transmembrane transporter activity
EH206_RS01580	COG2095	MarC family integral membrane protein
EH206_RS01585	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EH206_RS01600	COG0747	negative chemotaxis
EH206_RS01605	COG0601	transmembrane transport
EH206_RS01620	COG3275	phosphorelay sensor kinase activity
EH206_RS01625	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EH206_RS01630	COG0830	nickel cation binding
EH206_RS01635	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
EH206_RS01640	COG0804	urea catabolic process
EH206_RS01645	COG0832	Belongs to the urease beta subunit family
EH206_RS01650	COG0831	urea catabolic process
EH206_RS01655	COG0829	nickel cation binding
EH206_RS01680	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EH206_RS01685	COG1523	belongs to the glycosyl hydrolase 13 family
EH206_RS01690	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EH206_RS01695	COG0297	glycogen (starch) synthase activity
EH206_RS01700	COG0058	SHG alpha-glucan phosphorylase activity
EH206_RS01705	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
EH206_RS01730	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
EH206_RS01735	COG0437	4 iron, 4 sulfur cluster binding
EH206_RS01745	COG2414	aldehyde ferredoxin oxidoreductase
EH206_RS01750	COG0437	4 iron, 4 sulfur cluster binding
EH206_RS01755	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EH206_RS01800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EH206_RS01820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EH206_RS01825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EH206_RS01830	COG0705	Rhomboid family
EH206_RS01835	COG1349	DNA-binding transcription factor activity
EH206_RS01840	COG0058	SHG alpha-glucan phosphorylase activity
EH206_RS01845	COG1640	4-alpha-glucanotransferase
EH206_RS01850	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EH206_RS01850	COG0316	Belongs to the HesB IscA family
EH206_RS01855	COG1040	competence protein
EH206_RS01860	COG2267	carboxylic ester hydrolase activity
EH206_RS01865	COG1785	Belongs to the alkaline phosphatase family
EH206_RS01885	COG2852	Protein conserved in bacteria
EH206_RS01890	COG2183	response to ionizing radiation
EH206_RS01900	COG0028	Belongs to the TPP enzyme family
EH206_RS01905	COG2011	ABC-type metal ion transport system permease component
EH206_RS01910	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EH206_RS01925	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EH206_RS01940	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EH206_RS01945	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EH206_RS01950	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EH206_RS01955	COG1011	Hydrolase
EH206_RS01965	COG0494	nUDIX hydrolase
EH206_RS01970	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EH206_RS01995	COG4796	Type ii and iii secretion system protein
EH206_RS02000	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EH206_RS02005	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EH206_RS02020	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EH206_RS02025	COG0546	phosphoglycolate phosphatase activity
EH206_RS02030	COG0180	Tryptophanyl-tRNA synthetase
EH206_RS02035	COG1473	amidohydrolase
EH206_RS02060	COG1648	precorrin-2 dehydrogenase activity
EH206_RS02060	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EH206_RS02065	COG4948	Mandelate Racemase Muconate Lactonizing
EH206_RS02070	COG0747	negative chemotaxis
EH206_RS02075	COG0601	transmembrane transport
EH206_RS02080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH206_RS02085	COG0444	Belongs to the ABC transporter superfamily
EH206_RS02090	COG4608	Belongs to the ABC transporter superfamily
EH206_RS02095	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EH206_RS02105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EH206_RS02110	COG1765	OsmC-like protein
EH206_RS02115	COG3954	Phosphoribulokinase
EH206_RS02120	COG3089	Belongs to the UPF0270 family
EH206_RS02130	COG0488	(ABC) transporter
EH206_RS02135	COG2249	NAD(P)H dehydrogenase (quinone) activity
EH206_RS02145	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EH206_RS02150	COG1047	Peptidyl-prolyl cis-trans
EH206_RS02155	COG2900	Belongs to the SlyX family
EH206_RS02160	COG0545	Peptidyl-prolyl cis-trans isomerase
EH206_RS02165	COG2964	Protein conserved in bacteria
EH206_RS02170	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EH206_RS02175	COG2923	Belongs to the DsrF TusC family
EH206_RS02180	COG2168	tRNA wobble position uridine thiolation
EH206_RS02185	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EH206_RS02190	COG0049	tRNA binding
EH206_RS02200	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EH206_RS02215	COG0051	transcription antitermination factor activity, RNA binding
EH206_RS02220	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EH206_RS02225	COG0088	Forms part of the polypeptide exit tunnel
EH206_RS02230	COG0089	rRNA binding
EH206_RS02235	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EH206_RS02240	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EH206_RS02245	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EH206_RS02250	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EH206_RS02255	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EH206_RS02275	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EH206_RS02280	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EH206_RS02285	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EH206_RS02290	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EH206_RS02295	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EH206_RS02305	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EH206_RS02310	COG1841	ribosomal large subunit assembly
EH206_RS02315	COG0200	Binds to the 23S rRNA
EH206_RS02320	COG0201	protein transport
EH206_RS02325	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EH206_RS02330	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EH206_RS02340	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EH206_RS02345	COG0202	RNA polymerase activity
EH206_RS02350	COG0203	ribosomal protein L17
EH206_RS02360	COG3036	rescue of stalled ribosome
EH206_RS02365	COG1970	mechanosensitive ion channel activity
EH206_RS02370	COG0569	domain protein
EH206_RS02375	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EH206_RS02375	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EH206_RS02380	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EH206_RS02385	COG0242	peptide deformylase activity
EH206_RS02390	COG0758	DNA mediated transformation
EH206_RS02395	COG2922	Belongs to the Smg family
EH206_RS02400	COG0551	DNA topoisomerase type I activity
EH206_RS02405	COG0009	L-threonylcarbamoyladenylate synthase
EH206_RS02410	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EH206_RS02420	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EH206_RS02445	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EH206_RS02450	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EH206_RS02460	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
EH206_RS02465	COG1414	Transcriptional regulator
EH206_RS02470	COG1410	methionine synthase
EH206_RS02470	COG0646	methionine synthase
EH206_RS02490	COG1283	sodium-dependent phosphate transmembrane transporter activity
EH206_RS02495	COG0527	aspartate kinase activity
EH206_RS02500	COG0166	Belongs to the GPI family
EH206_RS02515	COG1509	lysine 2,3-aminomutase activity
EH206_RS02525	COG5510	response to toxic substance
EH206_RS02535	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
EH206_RS02540	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
EH206_RS02545	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EH206_RS02550	COG1053	succinate dehydrogenase
EH206_RS02555	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EH206_RS02560	COG1511	domain protein
EH206_RS02560	COG3264	Mechanosensitive ion channel
EH206_RS02565	COG0688	phosphatidylethanolamine metabolic process
EH206_RS02570	COG1162	GTPase activity
EH206_RS02575	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EH206_RS02600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EH206_RS02610	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EH206_RS02615	COG0028	Belongs to the TPP enzyme family
EH206_RS02635	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EH206_RS02640	COG1024	Enoyl-CoA hydratase
EH206_RS02645	COG1063	alcohol dehydrogenase
EH206_RS02650	COG0318	PFAM AMP-dependent synthetase and ligase
EH206_RS02710	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EH206_RS02720	COG0583	DNA-binding transcription factor activity
EH206_RS02730	COG1335	isochorismatase
EH206_RS02760	COG2814	Major facilitator Superfamily
EH206_RS02770	COG1566	PFAM secretion protein HlyD family protein
EH206_RS02800	COG1174	glycine betaine transport
EH206_RS02815	COG2986	histidine ammonia-lyase
EH206_RS02830	COG0402	S-adenosylhomocysteine deaminase activity
EH206_RS02835	COG1228	amidohydrolase
EH206_RS02845	COG2188	Transcriptional regulator
EH206_RS02865	COG3634	alkyl hydroperoxide reductase activity
EH206_RS02870	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EH206_RS02875	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EH206_RS02875	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EH206_RS02880	COG0802	atpase or kinase
EH206_RS02885	COG0860	N-Acetylmuramoyl-L-alanine amidase
EH206_RS02890	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EH206_RS02895	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EH206_RS02905	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EH206_RS02910	COG0330	HflC and HflK could
EH206_RS02915	COG0330	HflC and HflK could
EH206_RS02920	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
EH206_RS02925	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EH206_RS02935	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EH206_RS02940	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EH206_RS02945	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EH206_RS02950	COG1678	Uncharacterized ACR, COG1678
EH206_RS02955	COG0189	ligase activity
EH206_RS02960	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EH206_RS02965	COG2356	endonuclease I
EH206_RS02970	COG3091	SprT-like family
EH206_RS02975	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EH206_RS02980	COG1166	arginine decarboxylase activity
EH206_RS02990	COG0501	Belongs to the peptidase M48B family
EH206_RS02995	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EH206_RS03000	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EH206_RS03005	COG0126	phosphoglycerate kinase activity
EH206_RS03025	COG1279	arginine transmembrane transporter activity
EH206_RS03035	COG0583	DNA-binding transcription factor activity
EH206_RS03040	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EH206_RS03045	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EH206_RS03055	COG0604	alcohol dehydrogenase
EH206_RS03060	COG0488	(ABC) transporter
EH206_RS03070	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
EH206_RS03075	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EH206_RS03085	COG2207	Transcriptional regulator
EH206_RS03085	COG3708	Transcriptional regulator
EH206_RS03090	COG3045	CreA protein
EH206_RS03095	COG0745	RESPONSE REGULATOR receiver
EH206_RS03105	COG4172	Belongs to the ABC transporter superfamily
EH206_RS03120	COG0601	transmembrane transport
EH206_RS03125	COG0747	negative chemotaxis
EH206_RS03130	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EH206_RS03145	COG0083	homoserine kinase activity
EH206_RS03160	COG0583	DNA-binding transcription factor activity
EH206_RS03165	COG3181	Tripartite tricarboxylate transporter family receptor
EH206_RS03180	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EH206_RS03185	COG3022	response to hydroperoxide
EH206_RS03190	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EH206_RS03200	COG0521	Mo-molybdopterin cofactor biosynthetic process
EH206_RS03210	COG1584	GPR1 FUN34 yaaH family protein
EH206_RS03215	COG0443	Heat shock 70 kDa protein
EH206_RS03220	COG0484	heat shock protein binding
EH206_RS03225	COG0268	Binds directly to 16S ribosomal RNA
EH206_RS03230	COG0196	riboflavin kinase activity
EH206_RS03235	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EH206_RS03240	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EH206_RS03245	COG1047	Peptidyl-prolyl cis-trans
EH206_RS03250	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EH206_RS03255	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EH206_RS03260	COG0505	Belongs to the CarA family
EH206_RS03270	COG1028	Short-chain dehydrogenase reductase Sdr
EH206_RS03280	COG2966	Psort location CytoplasmicMembrane, score
EH206_RS03285	COG3610	response to peptide
EH206_RS03290	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EH206_RS03295	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EH206_RS03300	COG2967	ApaG domain
EH206_RS03305	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EH206_RS03310	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EH206_RS03315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EH206_RS03320	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EH206_RS03325	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EH206_RS03330	COG0564	pseudouridine synthase activity
EH206_RS03335	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EH206_RS03340	COG0417	DNA replication proofreading
EH206_RS03345	COG3706	GGDEF domain
EH206_RS03365	COG0411	ABC transporter
EH206_RS03375	COG0586	Pfam SNARE associated Golgi protein
EH206_RS03380	COG0440	acetolactate synthase activity
EH206_RS03385	COG0028	Belongs to the TPP enzyme family
EH206_RS03395	COG1012	belongs to the aldehyde dehydrogenase family
EH206_RS03395	COG1454	alcohol dehydrogenase
EH206_RS03400	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
EH206_RS03405	COG1178	ABC-type Fe3 transport system permease component
EH206_RS03410	COG4143	(ABC) transporter
EH206_RS03415	COG4533	DNA binding
EH206_RS03425	COG0066	3-isopropylmalate dehydratase activity
EH206_RS03430	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EH206_RS03435	COG0473	3-isopropylmalate dehydrogenase activity
EH206_RS03440	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EH206_RS03450	COG1022	Amp-dependent synthetase and ligase
EH206_RS03455	COG0028	Belongs to the TPP enzyme family
EH206_RS03465	COG1609	Transcriptional regulator
EH206_RS03475	COG0242	peptide deformylase activity
EH206_RS03490	COG0275	rRNA processing
EH206_RS03495	COG3116	cell division
EH206_RS03500	COG0768	penicillin binding
EH206_RS03505	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EH206_RS03510	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EH206_RS03515	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EH206_RS03520	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EH206_RS03525	COG0772	Belongs to the SEDS family
EH206_RS03530	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EH206_RS03535	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EH206_RS03540	COG1181	Belongs to the D-alanine--D-alanine ligase family
EH206_RS03545	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EH206_RS03550	COG0849	cell division
EH206_RS03555	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EH206_RS03560	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EH206_RS03575	COG0653	protein targeting
EH206_RS03580	COG0494	nUDIX hydrolase
EH206_RS03585	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EH206_RS03590	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
EH206_RS03595	COG0237	dephospho-CoA kinase activity
EH206_RS03605	COG0516	GMP reductase activity
EH206_RS03610	COG1459	type II secretion system
EH206_RS03615	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EH206_RS03620	COG4969	Belongs to the N-Me-Phe pilin family
EH206_RS03640	COG3725	Membrane protein required for beta-lactamase induction
EH206_RS03645	COG1113	amino acid transport
EH206_RS03655	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EH206_RS03660	COG0508	dehydrogenase complex catalyzes the overall conversion of
EH206_RS03665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EH206_RS03685	COG2079	MmgE PrpD family protein
EH206_RS03720	COG2079	MmgE PrpD family protein
EH206_RS03725	COG0765	amino acid transport
EH206_RS03730	COG0765	amino acid transport
EH206_RS03735	COG1126	abc transporter atp-binding protein
EH206_RS03745	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EH206_RS03755	COG1902	pentaerythritol trinitrate reductase activity
EH206_RS03760	COG3112	Uncharacterised protein family (UPF0231)
EH206_RS03770	COG4680	protein conserved in bacteria
EH206_RS03785	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EH206_RS03790	COG1349	DNA-binding transcription factor activity
EH206_RS03795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EH206_RS03800	COG0129	dihydroxy-acid dehydratase activity
EH206_RS03805	COG2610	gluconate transmembrane transporter activity
EH206_RS03810	COG1414	Transcriptional regulator
EH206_RS03820	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EH206_RS03825	COG0432	Pfam Uncharacterised protein family UPF0047
EH206_RS03830	COG0840	transmembrane signaling receptor activity
EH206_RS03835	COG0589	response to stress
EH206_RS03840	COG1448	Aminotransferase
EH206_RS03850	COG1522	sequence-specific DNA binding
EH206_RS03860	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EH206_RS03880	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EH206_RS03890	COG3093	addiction module antidote protein HigA
EH206_RS03900	COG0583	DNA-binding transcription factor activity
EH206_RS03910	COG0640	Transcriptional regulator
EH206_RS03915	COG0583	DNA-binding transcription factor activity
EH206_RS03920	COG0477	Major facilitator Superfamily
EH206_RS03925	COG0318	PFAM AMP-dependent synthetase and ligase
EH206_RS03925	COG0204	Acyl-transferase
EH206_RS03930	COG0477	Major facilitator Superfamily
EH206_RS03935	COG2153	protein acetylation
EH206_RS03960	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EH206_RS03965	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EH206_RS03970	COG1872	DUF167
EH206_RS03975	COG0762	integral membrane protein
EH206_RS03980	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EH206_RS03985	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EH206_RS03990	COG2805	Type II/IV secretion system protein
EH206_RS04000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH206_RS04005	COG0765	amino acid transport
EH206_RS04010	COG0765	amino acid transport
EH206_RS04015	COG1126	abc transporter atp-binding protein
EH206_RS04020	COG0402	S-adenosylhomocysteine deaminase activity
EH206_RS04030	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EH206_RS04045	COG1959	2 iron, 2 sulfur cluster binding
EH206_RS04050	COG0557	exoribonuclease II activity
EH206_RS04055	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EH206_RS04060	COG3766	membrane
EH206_RS04065	COG3650	response to hydrogen peroxide
EH206_RS04070	COG1073	alpha beta
EH206_RS04075	COG0747	negative chemotaxis
EH206_RS04080	COG0601	transmembrane transport
EH206_RS04085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH206_RS04090	COG0444	Belongs to the ABC transporter superfamily
EH206_RS04100	COG0360	Binds together with S18 to 16S ribosomal RNA
EH206_RS04105	COG2965	DNA replication, synthesis of RNA primer
EH206_RS04110	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EH206_RS04115	COG0359	binds to the 23S rRNA
EH206_RS04120	COG3061	Opacity-associated protein A
EH206_RS04125	COG0545	Peptidyl-prolyl cis-trans isomerase
EH206_RS04135	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EH206_RS04155	COG0410	ABC transporter
EH206_RS04160	COG1137	ATPase activity
EH206_RS04165	COG4177	L-phenylalanine transmembrane transporter activity
EH206_RS04175	COG0683	leucine binding
EH206_RS04205	COG1253	flavin adenine dinucleotide binding
EH206_RS04210	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EH206_RS04215	COG0729	surface antigen
EH206_RS04225	COG2105	PFAM AIG2 family protein
EH206_RS04230	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH206_RS04235	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EH206_RS04240	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EH206_RS04245	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EH206_RS04250	COG1968	undecaprenyl-diphosphatase activity
EH206_RS04255	COG0617	tRNA 3'-terminal CCA addition
EH206_RS04260	COG4991	sh3 domain protein
EH206_RS04265	COG3025	triphosphatase activity
EH206_RS04270	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EH206_RS04275	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EH206_RS04275	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EH206_RS04280	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EH206_RS04285	COG3530	Putative quorum-sensing-regulated virulence factor
EH206_RS04300	COG0840	transmembrane signaling receptor activity
EH206_RS04305	COG2721	sulfolactate sulfo-lyase activity
EH206_RS04310	COG2271	Major facilitator Superfamily
EH206_RS04320	COG2084	Dehydrogenase
EH206_RS04325	COG1929	Belongs to the glycerate kinase type-1 family
EH206_RS04330	COG3437	response regulator, receiver
EH206_RS04330	COG3850	Histidine kinase
EH206_RS04330	COG2205	protein histidine kinase activity
EH206_RS04330	COG4999	Histidine kinase
EH206_RS04335	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EH206_RS04340	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EH206_RS04345	COG3956	TIGRFAM MazG family protein
EH206_RS04350	COG0504	CTP synthase activity
EH206_RS04355	COG0148	phosphopyruvate hydratase activity
EH206_RS04365	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EH206_RS04375	COG0602	queuosine metabolic process
EH206_RS04380	COG0720	synthase
EH206_RS04385	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EH206_RS04390	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EH206_RS04395	COG0175	sulfate reduction
EH206_RS04400	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EH206_RS04400	COG1648	precorrin-2 dehydrogenase activity
EH206_RS04405	COG0175	sulfate reduction
EH206_RS04410	COG2895	sulfate adenylyltransferase (ATP) activity
EH206_RS04415	COG0529	Catalyzes the synthesis of activated sulfate
EH206_RS04425	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EH206_RS04430	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EH206_RS04435	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EH206_RS04440	COG0585	pseudouridine synthase activity
EH206_RS04445	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EH206_RS04450	COG4942	peptidase
EH206_RS04450	COG1388	LysM domain
EH206_RS04460	COG0442	prolyl-tRNA aminoacylation
EH206_RS04465	COG1720	tRNA m6t6A37 methyltransferase activity
EH206_RS04475	COG1464	Belongs to the NlpA lipoprotein family
EH206_RS04480	COG2011	ABC-type metal ion transport system permease component
EH206_RS04485	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EH206_RS04490	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EH206_RS04530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EH206_RS04535	COG1042	CoA-binding domain protein
EH206_RS04535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EH206_RS04535	COG0045	succinate-CoA ligase (ADP-forming) activity
EH206_RS04540	COG3148	PFAM DTW domain containing protein
EH206_RS04545	COG3118	belongs to the thioredoxin family
EH206_RS04550	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EH206_RS04560	COG2814	Major facilitator Superfamily
EH206_RS04565	COG1566	PFAM secretion protein HlyD family protein
EH206_RS04570	COG1846	Transcriptional regulator
EH206_RS04580	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EH206_RS04585	COG2113	Glycine betaine
EH206_RS04590	COG4176	ABC-type proline glycine betaine transport system permease component
EH206_RS04595	COG4175	Glycine betaine
EH206_RS04625	COG0765	amino acid transport
EH206_RS04630	COG1126	abc transporter atp-binding protein
EH206_RS04635	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EH206_RS04650	COG0436	Aminotransferase
EH206_RS04655	COG0235	Class ii aldolase
EH206_RS04660	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
EH206_RS04665	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EH206_RS04670	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EH206_RS04680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EH206_RS04695	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EH206_RS04700	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EH206_RS04710	COG1960	acyl-CoA dehydrogenase activity
EH206_RS04715	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EH206_RS04720	COG0121	glutamine amidotransferase
EH206_RS04725	COG3034	peptidoglycan biosynthetic process
EH206_RS04730	COG2226	methyltransferase
EH206_RS04735	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EH206_RS04740	COG2195	Cleaves the N-terminal amino acid of tripeptides
EH206_RS04750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH206_RS04760	COG0747	negative chemotaxis
EH206_RS04770	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EH206_RS04780	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EH206_RS04785	COG1073	alpha beta
EH206_RS04795	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EH206_RS04800	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EH206_RS04835	COG2161	toxin-antitoxin pair type II binding
EH206_RS04865	COG2026	Addiction module toxin, RelE StbE family
EH206_RS04970	COG3829	transcription factor binding
EH206_RS05005	COG3501	Rhs element vgr protein
EH206_RS05035	COG3209	COG3209 Rhs family protein
EH206_RS05080	COG3209	COG3209 Rhs family protein
EH206_RS05140	COG1546	Belongs to the CinA family
EH206_RS05145	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EH206_RS05150	COG2137	regulation of response to DNA damage stimulus
EH206_RS05155	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EH206_RS05160	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EH206_RS05185	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EH206_RS05190	COG1238	metal cluster binding
EH206_RS05195	COG2918	glutathione biosynthetic process
EH206_RS05200	COG1854	S-ribosylhomocysteine lyase activity
EH206_RS05205	COG4137	Cytochrome C assembly protein
EH206_RS05210	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EH206_RS05215	COG0228	four-way junction DNA binding
EH206_RS05220	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EH206_RS05225	COG0336	Belongs to the RNA methyltransferase TrmD family
EH206_RS05240	COG3279	Response regulator of the LytR AlgR family
EH206_RS05245	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EH206_RS05250	COG0287	Prephenate dehydrogenase
EH206_RS05250	COG1605	Chorismate mutase
EH206_RS05255	COG0077	Prephenate dehydratase
EH206_RS05255	COG1605	Chorismate mutase
EH206_RS05260	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EH206_RS05265	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EH206_RS05275	COG0564	pseudouridine synthase activity
EH206_RS05285	COG0542	response to heat
EH206_RS05320	COG3021	interspecies interaction between organisms
EH206_RS05325	COG0741	lytic transglycosylase activity
EH206_RS05325	COG1388	LysM domain
EH206_RS05330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EH206_RS05335	COG2226	methyltransferase
EH206_RS05340	COG0328	RNA-DNA hybrid ribonuclease activity
EH206_RS05345	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EH206_RS05375	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EH206_RS05405	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EH206_RS05415	COG1780	Probably involved in ribonucleotide reductase function
EH206_RS05420	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EH206_RS05425	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EH206_RS05430	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EH206_RS05440	COG3842	ATPase activity
EH206_RS05445	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EH206_RS05450	COG0288	reversible hydration of carbon dioxide
EH206_RS05455	COG1131	(ABC) transporter
EH206_RS05460	COG0842	Transport permease protein
EH206_RS05465	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EH206_RS05470	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EH206_RS05475	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EH206_RS05480	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EH206_RS05490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EH206_RS05500	COG1489	DNA binding
EH206_RS05505	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EH206_RS05510	COG1643	Atp-dependent helicase
EH206_RS05515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EH206_RS05520	COG1120	ATPase activity
EH206_RS05525	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EH206_RS05535	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EH206_RS05545	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EH206_RS05550	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EH206_RS05555	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EH206_RS05565	COG3835	regulator
EH206_RS05570	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EH206_RS05580	COG4208	sulfate ABC transporter
EH206_RS05585	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EH206_RS05620	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EH206_RS05625	COG2819	hydrolase of the alpha beta superfamily
EH206_RS05640	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EH206_RS05645	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
EH206_RS05650	COG0513	Belongs to the DEAD box helicase family
EH206_RS05655	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EH206_RS05660	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EH206_RS05675	COG3026	antisigma factor binding
EH206_RS05680	COG3086	response to oxidative stress
EH206_RS05685	COG0481	GTPase activity
EH206_RS05690	COG0681	Belongs to the peptidase S26 family
EH206_RS05695	COG0571	ribonuclease III activity
EH206_RS05705	COG1381	Involved in DNA repair and RecF pathway recombination
EH206_RS05710	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EH206_RS05715	COG0736	holo-[acyl-carrier-protein] synthase activity
EH206_RS05720	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EH206_RS05725	COG2200	EAL domain
EH206_RS05735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EH206_RS05740	COG2274	protein secretion by the type I secretion system
EH206_RS05770	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EH206_RS05775	COG0560	Phosphoserine phosphatase
EH206_RS05795	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EH206_RS05800	COG0047	phosphoribosylformylglycinamidine synthase activity
EH206_RS05800	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EH206_RS05805	COG2205	protein histidine kinase activity
EH206_RS05810	COG3170	Tfp pilus assembly protein FimV
EH206_RS05815	COG2204	response regulator
EH206_RS05820	COG0347	Belongs to the P(II) protein family
EH206_RS05830	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EH206_RS05835	COG2814	Major facilitator Superfamily
EH206_RS05840	COG3683	transport system, periplasmic component
EH206_RS05845	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
EH206_RS05855	COG1120	ATPase activity
EH206_RS05860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EH206_RS05870	COG0483	inositol monophosphate 1-phosphatase activity
EH206_RS05875	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EH206_RS05880	COG1959	2 iron, 2 sulfur cluster binding
EH206_RS05885	COG1104	cysteine desulfurase activity
EH206_RS05890	COG0822	iron-sulfur transferase activity
EH206_RS05895	COG0316	Belongs to the HesB IscA family
EH206_RS05900	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EH206_RS05905	COG0443	Heat shock 70 kDa protein
EH206_RS05910	COG0633	Ferredoxin
EH206_RS05915	COG2975	iron-sulfur cluster assembly
EH206_RS05920	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EH206_RS05935	COG2897	thiosulfate sulfurtransferase activity
EH206_RS05945	COG0105	UTP biosynthetic process
EH206_RS05950	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EH206_RS05960	COG1426	Protein conserved in bacteria
EH206_RS05965	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EH206_RS05970	COG0124	histidyl-tRNA synthetase
EH206_RS05975	COG2976	Protein conserved in bacteria
EH206_RS05980	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EH206_RS05985	COG1160	GTP binding
EH206_RS05995	COG1645	bacterial-type flagellum-dependent swarming motility
EH206_RS06010	COG1570	exodeoxyribonuclease VII activity
EH206_RS06015	COG0517	IMP dehydrogenase activity
EH206_RS06015	COG0516	GMP reductase activity
EH206_RS06020	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EH206_RS06020	COG0519	Catalyzes the synthesis of GMP from XMP
EH206_RS06035	COG1846	Transcriptional regulator
EH206_RS06050	COG1063	alcohol dehydrogenase
EH206_RS06065	COG0411	ABC transporter
EH206_RS06080	COG1012	belongs to the aldehyde dehydrogenase family
EH206_RS06090	COG2207	Transcriptional regulator
EH206_RS06105	COG0698	ribose 5-phosphate isomerase
EH206_RS06110	COG1737	Transcriptional regulator
EH206_RS06115	COG1879	ABC-type sugar transport system periplasmic component
EH206_RS06120	COG1129	ABC transporter
EH206_RS06125	COG1172	Belongs to the binding-protein-dependent transport system permease family
EH206_RS06130	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EH206_RS06135	COG1940	carbohydrate kinase activity
EH206_RS06145	COG0436	Aminotransferase
EH206_RS06150	COG0583	DNA-binding transcription factor activity
EH206_RS06160	COG2391	methyltransferase activity
EH206_RS06165	COG0425	Belongs to the sulfur carrier protein TusA family
EH206_RS06170	COG0583	DNA-binding transcription factor activity
EH206_RS06200	COG1464	Belongs to the NlpA lipoprotein family
EH206_RS06205	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EH206_RS06210	COG2011	ABC-type metal ion transport system permease component
EH206_RS06215	COG1609	Transcriptional regulator
EH206_RS06225	COG0601	transmembrane transport
EH206_RS06230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH206_RS06235	COG4608	Belongs to the ABC transporter superfamily
EH206_RS06240	COG0444	Belongs to the ABC transporter superfamily
EH206_RS06245	COG0154	amidase activity
EH206_RS06250	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EH206_RS06255	COG0351	phosphomethylpyrimidine kinase
EH206_RS06260	COG1830	Aldolase
EH206_RS06265	COG3223	Belongs to the PsiE family
EH206_RS06275	COG1597	lipid kinase activity
EH206_RS06280	COG0826	peptidase U32
EH206_RS06290	COG0435	Glutathione S-transferase
EH206_RS06295	COG0745	RESPONSE REGULATOR receiver
EH206_RS06300	COG2205	protein histidine kinase activity
EH206_RS06305	COG0477	Major facilitator Superfamily
EH206_RS06310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EH206_RS06315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EH206_RS06320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EH206_RS06325	COG3265	gluconokinase activity
EH206_RS06335	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EH206_RS06350	COG1609	Transcriptional regulator
EH206_RS06365	COG2239	Acts as a magnesium transporter
EH206_RS06380	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EH206_RS06395	COG1760	l-serine dehydratase
EH206_RS06400	COG0814	amino acid
EH206_RS06405	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EH206_RS06410	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EH206_RS06415	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EH206_RS06420	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EH206_RS06430	COG0215	cysteine-tRNA ligase activity
EH206_RS06435	COG2501	S4 domain
EH206_RS06440	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EH206_RS06455	COG1447	Phosphotransferase system cellobiose-specific component IIA
EH206_RS06460	COG2186	Transcriptional regulator
EH206_RS06475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH206_RS06480	COG0405	Gamma-glutamyltransferase
EH206_RS06485	COG4172	Belongs to the ABC transporter superfamily
EH206_RS06490	COG0071	Belongs to the small heat shock protein (HSP20) family
EH206_RS06500	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EH206_RS06525	COG3122	Protein conserved in bacteria
EH206_RS06535	COG1196	nuclear chromosome segregation
EH206_RS06535	COG3264	Mechanosensitive ion channel
EH206_RS06545	COG4948	Mandelate Racemase Muconate Lactonizing
EH206_RS06555	COG0436	Aminotransferase
EH206_RS06570	COG0513	Belongs to the DEAD box helicase family
EH206_RS06585	COG2354	Protein conserved in bacteria
EH206_RS06600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH206_RS06675	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EH206_RS06685	COG0582	viral genome integration into host DNA
EH206_RS06695	COG2116	formate transmembrane transporter activity
EH206_RS06705	COG0579	oxidoreductase
EH206_RS06715	COG3691	Protein conserved in bacteria
EH206_RS06725	COG0183	Belongs to the thiolase family
EH206_RS06730	COG1250	3-hydroxyacyl-CoA dehydrogenase
EH206_RS06730	COG1024	Enoyl-CoA hydratase
EH206_RS06735	COG2062	phosphohistidine phosphatase, SixA
EH206_RS06740	COG2840	Smr protein MutS2
EH206_RS06745	COG2890	protein-(glutamine-N5) methyltransferase activity
EH206_RS06750	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EH206_RS06755	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
EH206_RS06760	COG0730	response to heat
EH206_RS06765	COG3101	peptidyl-lysine hydroxylation
EH206_RS06775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EH206_RS06775	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EH206_RS06780	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EH206_RS06790	COG0697	spore germination
EH206_RS06795	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EH206_RS06800	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EH206_RS06805	COG0101	tRNA pseudouridine synthase activity
EH206_RS06810	COG0586	Pfam SNARE associated Golgi protein
EH206_RS06820	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EH206_RS06825	COG0285	dihydrofolate synthase activity
EH206_RS06830	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
EH206_RS06835	COG1286	toxin biosynthetic process
EH206_RS06840	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EH206_RS06845	COG0163	prenyltransferase activity
EH206_RS06855	COG4215	(ABC) transporter
EH206_RS06865	COG4598	ABC transporter
EH206_RS06870	COG1090	epimerase
EH206_RS06875	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EH206_RS06880	COG0625	glutathione transferase activity
EH206_RS06885	COG0531	amino acid
EH206_RS06890	COG4303	Ethanolamine ammonia lyase large subunit
EH206_RS06895	COG4302	ethanolamine ammonia-lyase activity
EH206_RS06900	COG0622	Phosphoesterase
EH206_RS06905	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EH206_RS06920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH206_RS06925	COG1609	Transcriptional regulator
EH206_RS06930	COG0857	belongs to the CobB CobQ family
EH206_RS06930	COG0280	phosphate acetyltransferase
EH206_RS06935	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EH206_RS06940	COG3092	negative regulation of chromosome organization
EH206_RS06945	COG3013	Belongs to the UPF0304 family
EH206_RS06950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EH206_RS06955	COG0471	metal ion transport
EH206_RS06955	COG0490	domain, Protein
EH206_RS06960	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EH206_RS06965	COG0436	Aminotransferase
EH206_RS06970	COG0583	DNA-binding transcription factor activity
EH206_RS06985	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH206_RS06990	COG0649	NAD binding
EH206_RS06990	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH206_RS06995	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EH206_RS07000	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EH206_RS07010	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EH206_RS07015	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH206_RS07020	COG0839	Belongs to the complex I subunit 6 family
EH206_RS07025	COG0713	ATP synthesis coupled electron transport
EH206_RS07030	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EH206_RS07035	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH206_RS07040	COG1007	ATP synthesis coupled electron transport
EH206_RS07045	COG4575	ribosome binding
EH206_RS07055	COG0488	(ABC) transporter
EH206_RS07060	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
EH206_RS07065	COG0437	4 iron, 4 sulfur cluster binding
EH206_RS07070	COG5557	Pfam Polysulphide reductase, NrfD
EH206_RS07075	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
EH206_RS07080	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EH206_RS07085	COG1773	rubredoxin
EH206_RS07095	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EH206_RS07100	COG0298	carbon dioxide binding
EH206_RS07105	COG0409	Hydrogenase expression formation protein
EH206_RS07110	COG0309	Hydrogenase expression formation protein (HypE)
EH206_RS07115	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
EH206_RS07145	COG3383	formate dehydrogenase (NAD+) activity
EH206_RS07145	COG0243	molybdopterin cofactor binding
EH206_RS07150	COG0437	4 iron, 4 sulfur cluster binding
EH206_RS07155	COG2864	formate dehydrogenase
EH206_RS07160	COG3058	Necessary for formate dehydrogenase activity
EH206_RS07165	COG2814	Major facilitator Superfamily
EH206_RS07180	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EH206_RS07190	COG0840	transmembrane signaling receptor activity
EH206_RS07195	COG4807	Protein conserved in bacteria
EH206_RS07200	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EH206_RS07210	COG1129	ABC transporter
EH206_RS07215	COG1172	Belongs to the binding-protein-dependent transport system permease family
EH206_RS07230	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EH206_RS07235	COG1070	Carbohydrate kinase
EH206_RS07240	COG0640	Transcriptional regulator
EH206_RS07245	COG1902	pentaerythritol trinitrate reductase activity
EH206_RS07250	COG0626	cystathionine gamma-synthase activity
EH206_RS07260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EH206_RS07275	COG0765	amino acid transport
EH206_RS07280	COG0765	amino acid transport
EH206_RS07310	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EH206_RS07310	COG3008	intermembrane lipid transfer
EH206_RS07315	COG2995	paraquat-inducible protein a
EH206_RS07320	COG2995	paraquat-inducible protein a
EH206_RS07340	COG4948	Mandelate Racemase Muconate Lactonizing
EH206_RS07365	COG2814	Major facilitator Superfamily
EH206_RS07370	COG1082	Xylose isomerase domain protein TIM barrel
EH206_RS07375	COG3962	Belongs to the TPP enzyme family
EH206_RS07380	COG0837	glucose binding
EH206_RS07380	COG1737	Transcriptional regulator
EH206_RS07385	COG3718	enzyme involved in inositol metabolism
EH206_RS07390	COG1012	belongs to the aldehyde dehydrogenase family
EH206_RS07395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EH206_RS07400	COG0673	inositol 2-dehydrogenase activity
EH206_RS07405	COG1560	Kdo2-lipid A biosynthetic process
EH206_RS07410	COG3459	Glycosyltransferase 36 associated
EH206_RS07415	COG0784	Response regulator, receiver
EH206_RS07415	COG0835	chemotaxis
EH206_RS07420	COG4521	taurine ABC transporter
EH206_RS07425	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EH206_RS07430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH206_RS07435	COG0318	PFAM AMP-dependent synthetase and ligase
EH206_RS07440	COG1012	belongs to the aldehyde dehydrogenase family
EH206_RS07445	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH206_RS07450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH206_RS07455	COG1116	anion transmembrane transporter activity
EH206_RS07460	COG1882	Formate acetyltransferase
EH206_RS07465	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EH206_RS07470	COG2390	Transcriptional regulator
EH206_RS07475	COG0246	Mannitol dehydrogenase
EH206_RS07480	COG1070	Carbohydrate kinase
EH206_RS07485	COG1879	ABC-type sugar transport system periplasmic component
EH206_RS07490	COG1129	ABC transporter
EH206_RS07495	COG1172	Belongs to the binding-protein-dependent transport system permease family
EH206_RS07500	COG0840	transmembrane signaling receptor activity
EH206_RS07505	COG3214	Protein conserved in bacteria
EH206_RS07530	COG3228	Belongs to the MtfA family
EH206_RS07545	COG0401	homolog of Blt101
EH206_RS07555	COG3706	GGDEF domain
EH206_RS07575	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EH206_RS07580	COG0303	'Molybdopterin
EH206_RS07585	COG4172	Belongs to the ABC transporter superfamily
EH206_RS07590	COG0747	negative chemotaxis
EH206_RS07595	COG0601	transmembrane transport
EH206_RS07600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH206_RS07615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH206_RS07635	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EH206_RS07645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH206_RS07655	COG0281	malic enzyme
EH206_RS07660	COG0295	cytidine deaminase activity
EH206_RS07665	COG1346	cytolysis
EH206_RS07670	COG1380	Effector of murein hydrolase LrgA
EH206_RS07680	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EH206_RS07685	COG0156	8-amino-7-oxononanoate synthase activity
EH206_RS07690	COG2226	methyltransferase
EH206_RS07695	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EH206_RS07700	COG0556	nucleotide-excision repair
EH206_RS07710	COG0318	PFAM AMP-dependent synthetase and ligase
EH206_RS07735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH206_RS07740	COG1116	anion transmembrane transporter activity
EH206_RS07755	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EH206_RS07760	COG0521	Mo-molybdopterin cofactor biosynthetic process
EH206_RS07770	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EH206_RS07775	COG0314	molybdopterin synthase activity
EH206_RS07780	COG0670	Belongs to the BI1 family
EH206_RS07805	COG1309	transcriptional regulator
EH206_RS07810	COG0513	Belongs to the DEAD box helicase family
EH206_RS07825	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EH206_RS07830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EH206_RS07835	COG2040	homocysteine
EH206_RS07845	COG1053	succinate dehydrogenase
EH206_RS07850	COG1053	succinate dehydrogenase
EH206_RS07850	COG3976	FMN-binding domain protein
EH206_RS07850	COG0431	NADPH-dependent FMN reductase
EH206_RS07855	COG2267	carboxylic ester hydrolase activity
EH206_RS07875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH206_RS07880	COG0444	Belongs to the ABC transporter superfamily
EH206_RS07885	COG4608	Belongs to the ABC transporter superfamily
EH206_RS07900	COG1280	lysine exporter protein (LysE YggA)
EH206_RS07910	COG1686	Belongs to the peptidase S11 family
EH206_RS07920	COG1349	DNA-binding transcription factor activity
EH206_RS07925	COG1177	transmembrane transport
EH206_RS07930	COG3842	ATPase activity
EH206_RS07955	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EH206_RS07980	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EH206_RS07990	COG1126	abc transporter atp-binding protein
EH206_RS07995	COG0765	amino acid transport
EH206_RS08000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH206_RS08020	COG0783	Belongs to the Dps family
EH206_RS08035	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EH206_RS08045	COG0534	Mate efflux family protein
EH206_RS08080	COG3082	Protein of unknown function (DUF1414)
EH206_RS08085	COG3081	Nucleoid-associated protein
EH206_RS08100	COG2979	Protein of unknown function (DUF533)
EH206_RS08105	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EH206_RS08110	COG1067	ATP-dependent peptidase activity
EH206_RS08125	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
EH206_RS08130	COG3070	regulator of competence-specific genes
EH206_RS08135	COG1289	transmembrane transporter activity
EH206_RS08140	COG3304	Inner membrane component domain
EH206_RS08145	COG0210	DNA helicase
EH206_RS08150	COG1803	Methylglyoxal synthase
EH206_RS08155	COG1832	CoA-binding protein
EH206_RS08160	COG3785	DNA binding
EH206_RS08165	COG1254	Belongs to the acylphosphatase family
EH206_RS08170	COG2920	part of a sulfur-relay system
EH206_RS08180	COG0670	Belongs to the BI1 family
EH206_RS08220	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EH206_RS08240	COG0840	transmembrane signaling receptor activity
EH206_RS08255	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
EH206_RS08260	COG2943	transferase activity, transferring hexosyl groups
EH206_RS08265	COG2814	Major facilitator Superfamily
EH206_RS08270	COG1560	Kdo2-lipid A biosynthetic process
EH206_RS08275	COG1902	pentaerythritol trinitrate reductase activity
EH206_RS08280	COG1054	Belongs to the UPF0176 family
EH206_RS08285	COG2353	YceI-like domain
EH206_RS08290	COG3038	cytochrome b561
EH206_RS08310	COG0418	dihydroorotase activity
EH206_RS08320	COG1530	ribonuclease E activity
EH206_RS08325	COG0564	pseudouridine synthase activity
EH206_RS08330	COG0424	maF-like protein
EH206_RS08335	COG1399	metal-binding, possibly nucleic acid-binding protein
EH206_RS08340	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EH206_RS08345	COG0416	fatty acid biosynthetic process
EH206_RS08350	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EH206_RS08365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EH206_RS08370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EH206_RS08375	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EH206_RS08380	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EH206_RS08385	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EH206_RS08390	COG0470	DNA polymerase III
EH206_RS08395	COG0084	hydrolase, TatD family'
EH206_RS08400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EH206_RS08400	COG1263	PTS System
EH206_RS08405	COG0537	adenosine 5'-monophosphoramidase activity
EH206_RS08410	COG5633	Lipoprotein
EH206_RS08415	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
EH206_RS08425	COG1472	Belongs to the glycosyl hydrolase 3 family
EH206_RS08430	COG3150	esterase
EH206_RS08435	COG1252	NADH dehydrogenase
EH206_RS08440	COG3134	Outer membrane lipoprotein
EH206_RS08450	COG0443	Heat shock 70 kDa protein
EH206_RS08460	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EH206_RS08465	COG4591	ABC-type transport system involved in lipoprotein release permease component
EH206_RS08470	COG1136	(ABC) transporter
EH206_RS08475	COG4591	ABC-type transport system involved in lipoprotein release permease component
EH206_RS08480	COG1940	carbohydrate kinase activity
EH206_RS08495	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EH206_RS08500	COG2011	ABC-type metal ion transport system permease component
EH206_RS08505	COG1464	Belongs to the NlpA lipoprotein family
EH206_RS08520	COG4139	cobalamin transport
EH206_RS08525	COG0386	Belongs to the glutathione peroxidase family
EH206_RS08530	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
EH206_RS08535	COG0791	NLP P60 protein
EH206_RS08540	COG0095	Lipoate-protein ligase
EH206_RS08545	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EH206_RS08550	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EH206_RS08555	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EH206_RS08560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EH206_RS08565	COG4558	Periplasmic binding protein
EH206_RS08570	COG3720	iron ion transport
EH206_RS08575	COG0366	Alpha amylase catalytic
EH206_RS08575	COG0366	Alpha amylase catalytic
EH206_RS08580	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EH206_RS08585	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EH206_RS08585	COG0574	Belongs to the PEP-utilizing enzyme family
EH206_RS08600	COG0628	permease
EH206_RS08605	COG0277	FAD linked oxidase domain protein
EH206_RS08605	COG0247	lactate metabolic process
EH206_RS08610	COG2050	protein possibly involved in aromatic compounds catabolism
EH206_RS08620	COG0316	Belongs to the HesB IscA family
EH206_RS08625	COG0719	Fe-S assembly protein
EH206_RS08630	COG0396	ATPase activity
EH206_RS08635	COG0719	Fe-S assembly protein
EH206_RS08640	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EH206_RS08645	COG2166	iron-sulfur cluster assembly
EH206_RS08650	COG1376	ErfK ybiS ycfS ynhG family protein
EH206_RS08650	COG1388	LysM domain
EH206_RS08655	COG4238	major outer membrane lipoprotein
EH206_RS08675	COG2723	6-phospho-beta-galactosidase activity
EH206_RS08690	COG2188	Transcriptional regulator
EH206_RS08695	COG1301	dicarboxylic acid transport
EH206_RS08700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EH206_RS08710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH206_RS08720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH206_RS08725	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EH206_RS08730	COG0028	Belongs to the TPP enzyme family
EH206_RS08755	COG1053	succinate dehydrogenase
EH206_RS08770	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EH206_RS08775	COG0431	NADPH-dependent FMN reductase
EH206_RS08785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EH206_RS08805	COG2011	ABC-type metal ion transport system permease component
EH206_RS08815	COG0477	Major facilitator Superfamily
EH206_RS08840	COG1172	Belongs to the binding-protein-dependent transport system permease family
EH206_RS08850	COG0411	ABC transporter
EH206_RS08870	COG0583	DNA-binding transcription factor activity
EH206_RS08905	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EH206_RS08910	COG0671	phosphoesterase, PA-phosphatase related
EH206_RS08915	COG1879	ABC-type sugar transport system periplasmic component
EH206_RS08925	COG1129	ABC transporter
EH206_RS08930	COG1172	Belongs to the binding-protein-dependent transport system permease family
EH206_RS08935	COG3959	Transketolase, thiamine diphosphate binding domain
EH206_RS08940	COG3958	Transketolase
EH206_RS08945	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EH206_RS08950	COG1082	Xylose isomerase domain protein TIM barrel
EH206_RS08960	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
EH206_RS08965	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EH206_RS08970	COG0284	orotidine-5'-phosphate decarboxylase activity
EH206_RS08975	COG0023	Translation Initiation Factor
EH206_RS08980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH206_RS09010	COG0235	Class ii aldolase
EH206_RS09015	COG1966	Carbon starvation protein
EH206_RS09020	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
EH206_RS09025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EH206_RS09025	COG1263	PTS System
EH206_RS09030	COG1486	melibiose metabolic process
EH206_RS09035	COG2188	Transcriptional regulator
EH206_RS09055	COG4172	Belongs to the ABC transporter superfamily
EH206_RS09065	COG4171	peptide transport system, permease
EH206_RS09075	COG4166	transmembrane transport
EH206_RS09085	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EH206_RS09105	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EH206_RS09110	COG1842	Phage shock protein A
EH206_RS09120	COG1983	PspC domain protein
EH206_RS09130	COG3106	COG3106 Predicted ATPase
EH206_RS09135	COG3768	UPF0283 membrane protein
EH206_RS09140	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EH206_RS09150	COG1122	ATPase activity
EH206_RS09175	COG0477	Major facilitator Superfamily
EH206_RS09180	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EH206_RS09185	COG2866	Carboxypeptidase
EH206_RS09205	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EH206_RS09210	COG4166	transmembrane transport
EH206_RS09215	COG0598	Magnesium transport protein CorA
EH206_RS09225	COG0037	tRNA processing
EH206_RS09230	COG1487	ribonuclease activity
EH206_RS09250	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EH206_RS09255	COG2911	Protein conserved in bacteria
EH206_RS09265	COG1643	Atp-dependent helicase
EH206_RS09280	COG5001	Diguanylate cyclase
EH206_RS09280	COG3300	MHYT domain
EH206_RS09285	COG3591	Belongs to the peptidase S1B family
EH206_RS09305	COG2223	nitrite transmembrane transporter activity
EH206_RS09320	COG1028	Short-chain dehydrogenase reductase Sdr
EH206_RS09325	COG0659	secondary active sulfate transmembrane transporter activity
EH206_RS09330	COG0387	Pfam Sodium calcium exchanger
EH206_RS09335	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EH206_RS09350	COG2261	transglycosylase associated protein
EH206_RS09360	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EH206_RS09380	COG3842	ATPase activity
EH206_RS09390	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EH206_RS09395	COG1012	belongs to the aldehyde dehydrogenase family
EH206_RS09405	COG1176	ABC-type spermidine putrescine transport system, permease component I
EH206_RS09420	COG1028	Short-chain dehydrogenase reductase Sdr
EH206_RS09430	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EH206_RS09440	COG4792	protein secretion
EH206_RS09450	COG4794	Type iii secretion
EH206_RS09475	COG1157	protein secretion by the type III secretion system
EH206_RS09505	COG2197	response regulator
EH206_RS09525	COG4669	(LipO)protein
EH206_RS09610	COG1802	Transcriptional regulator
EH206_RS09645	COG0270	DNA (cytosine-5-)-methyltransferase activity
EH206_RS09675	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EH206_RS09730	COG1403	HNH endonuclease
EH206_RS09755	COG1724	mRNA binding
EH206_RS09760	COG1598	PFAM Uncharacterised protein family UPF0150
EH206_RS09860	COG4386	tail sheath protein
EH206_RS09880	COG1196	nuclear chromosome segregation
EH206_RS09880	COG0739	heme binding
EH206_RS09880	COG0741	lytic transglycosylase activity
EH206_RS09950	COG2831	hemolysin activation secretion protein
EH206_RS09975	COG3210	domain, Protein
EH206_RS10030	COG3210	domain, Protein
EH206_RS10075	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EH206_RS10090	COG1473	amidohydrolase
EH206_RS10095	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
EH206_RS10120	COG1940	carbohydrate kinase activity
EH206_RS10135	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EH206_RS10135	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EH206_RS10140	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EH206_RS10145	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH206_RS10145	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EH206_RS10145	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EH206_RS10150	COG3711	transcriptional antiterminator
EH206_RS10150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH206_RS10210	COG3501	Rhs element vgr protein
EH206_RS10285	COG2914	Belongs to the UPF0125 (RnfH) family
EH206_RS10295	COG4659	FMN binding
EH206_RS10305	COG4656	Part of a membrane complex involved in electron transport
EH206_RS10315	COG4657	Part of a membrane complex involved in electron transport
EH206_RS10320	COG2205	protein histidine kinase activity
EH206_RS10370	COG2076	Multidrug Resistance protein
EH206_RS10385	COG0583	DNA-binding transcription factor activity
EH206_RS10395	COG4771	TonB-dependent receptor
EH206_RS10400	COG1021	2,3-dihydroxybenzoate-AMP ligase
EH206_RS10420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EH206_RS10420	COG3433	isochorismatase activity
EH206_RS10420	COG2226	methyltransferase
EH206_RS10430	COG1132	(ABC) transporter
EH206_RS10430	COG2375	cellular response to nickel ion
EH206_RS10435	COG1132	(ABC) transporter
EH206_RS10440	COG2814	Major facilitator Superfamily
EH206_RS10445	COG0012	GTP binding
EH206_RS10450	COG0193	aminoacyl-tRNA hydrolase activity
EH206_RS10465	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EH206_RS10470	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EH206_RS10475	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EH206_RS10480	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EH206_RS10485	COG2890	protein-(glutamine-N5) methyltransferase activity
EH206_RS10495	COG2912	Transglutaminase-like superfamily
EH206_RS10500	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EH206_RS10510	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EH206_RS10515	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EH206_RS10570	COG1881	PFAM PEBP family protein
EH206_RS10580	COG1802	Transcriptional regulator
EH206_RS10605	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EH206_RS10625	COG3769	mannosylglycerate metabolic process
EH206_RS10630	COG1215	transferase activity, transferring glycosyl groups
EH206_RS10640	COG4221	oxidoreductase activity
EH206_RS10655	COG0477	Major facilitator Superfamily
EH206_RS10665	COG1940	carbohydrate kinase activity
EH206_RS10670	COG0583	DNA-binding transcription factor activity
EH206_RS10675	COG2814	Major facilitator Superfamily
EH206_RS10685	COG0114	fumarate hydratase activity
EH206_RS10690	COG1482	cell wall glycoprotein biosynthetic process
EH206_RS10695	COG5339	Protein conserved in bacteria
EH206_RS10705	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EH206_RS10710	COG0385	Bile acid
EH206_RS10715	COG0673	inositol 2-dehydrogenase activity
EH206_RS10725	COG1172	Belongs to the binding-protein-dependent transport system permease family
EH206_RS10730	COG1129	ABC transporter
EH206_RS10735	COG1879	ABC-type sugar transport system periplasmic component
EH206_RS10740	COG1069	ribulokinase activity
EH206_RS10745	COG2160	L-arabinose isomerase activity
EH206_RS10750	COG4657	Part of a membrane complex involved in electron transport
EH206_RS10755	COG2878	Part of a membrane complex involved in electron transport
EH206_RS10760	COG4656	Part of a membrane complex involved in electron transport
EH206_RS10765	COG4658	electron transport chain
EH206_RS10770	COG4659	FMN binding
EH206_RS10780	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EH206_RS10800	COG0616	signal peptide processing
EH206_RS10805	COG1028	Short-chain dehydrogenase reductase Sdr
EH206_RS10820	COG1187	pseudouridine synthase activity
EH206_RS10825	COG0243	molybdopterin cofactor binding
EH206_RS10830	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EH206_RS10830	COG2146	nitrite reductase [NAD(P)H] activity
EH206_RS10835	COG1116	anion transmembrane transporter activity
EH206_RS10845	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH206_RS10855	COG3707	response regulator
EH206_RS10860	COG0009	L-threonylcarbamoyladenylate synthase
EH206_RS10865	COG0613	PHP domain protein
EH206_RS10875	COG0512	Glutamine amidotransferase of anthranilate synthase
EH206_RS10880	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EH206_RS10885	COG0134	indole-3-glycerol-phosphate synthase activity
EH206_RS10885	COG0135	phosphoribosylanthranilate isomerase activity
EH206_RS10890	COG0133	tryptophan synthase activity
EH206_RS10895	COG0159	tryptophan synthase activity
EH206_RS10900	COG3047	cAMP biosynthetic process
EH206_RS10915	COG3423	Transcriptional regulator
EH206_RS11005	COG3179	chitinase
EH206_RS11045	COG4383	Mu-like prophage protein gp29
EH206_RS11070	COG4397	Mu-like prophage major head subunit gpT
EH206_RS11095	COG4386	tail sheath protein
EH206_RS11150	COG0727	PFAM Uncharacterised protein family (UPF0153)
EH206_RS11160	COG2917	probably involved in intracellular septation
EH206_RS11175	COG2350	Protein conserved in bacteria
EH206_RS11190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EH206_RS11195	COG3099	Belongs to the UPF0263 family
EH206_RS11200	COG4608	Belongs to the ABC transporter superfamily
EH206_RS11205	COG0444	Belongs to the ABC transporter superfamily
EH206_RS11210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH206_RS11225	COG1012	belongs to the aldehyde dehydrogenase family
EH206_RS11225	COG1454	alcohol dehydrogenase
EH206_RS11230	COG1435	thymidine kinase activity
EH206_RS11240	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EH206_RS11245	COG0745	RESPONSE REGULATOR receiver
EH206_RS11250	COG1752	Esterase of the alpha-beta hydrolase superfamily
EH206_RS11255	COG3012	SEC-C Motif Domain Protein
EH206_RS11260	COG0788	formyltetrahydrofolate deformylase activity
EH206_RS11275	COG2860	membrane
EH206_RS11280	COG0708	Exodeoxyribonuclease III
EH206_RS11295	COG0778	Nitroreductase
EH206_RS11300	COG0616	signal peptide processing
EH206_RS11305	COG1335	isochorismatase
EH206_RS11310	COG3139	Protein of unknown function (DUF1315)
EH206_RS11315	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EH206_RS11330	COG0656	L-ascorbic acid biosynthetic process
EH206_RS11335	COG3713	MltA-interacting MipA family protein
EH206_RS11340	COG2766	serine protein kinase
EH206_RS11345	COG2718	Belongs to the UPF0229 family
EH206_RS11350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EH206_RS11355	COG2719	SpoVR family
EH206_RS11360	COG2186	Transcriptional regulator
EH206_RS11365	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EH206_RS11375	COG2983	Belongs to the UPF0260 family
EH206_RS11380	COG0179	Fumarylacetoacetate (FAA) hydrolase
EH206_RS11390	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EH206_RS11395	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EH206_RS11405	COG0850	regulation of cytokinetic process
EH206_RS11410	COG2894	cell division
EH206_RS11415	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EH206_RS11420	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EH206_RS11425	COG0318	PFAM AMP-dependent synthetase and ligase
EH206_RS11430	COG3065	identical protein binding
EH206_RS11440	COG1199	ATP-dependent helicase activity
EH206_RS11445	COG0251	oxidation-reduction process
EH206_RS11460	COG0625	glutathione transferase activity
EH206_RS11465	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EH206_RS11470	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EH206_RS11475	COG0259	pyridoxamine-phosphate oxidase activity
EH206_RS11480	COG3895	Periplasmic Protein
EH206_RS11485	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EH206_RS11495	COG1846	Transcriptional regulator
EH206_RS11500	COG3313	Fe-S protein
EH206_RS11510	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EH206_RS11515	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EH206_RS11520	COG0791	NLP P60 protein
EH206_RS11530	COG1609	Transcriptional regulator
EH206_RS11540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EH206_RS11545	COG0307	riboflavin synthase, alpha
EH206_RS11550	COG0534	Mate efflux family protein
EH206_RS11570	COG2336	PFAM SpoVT AbrB
EH206_RS11590	COG0494	nUDIX hydrolase
EH206_RS11595	COG1760	l-serine dehydratase
EH206_RS11605	COG1253	flavin adenine dinucleotide binding
EH206_RS11610	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH206_RS11610	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EH206_RS11615	COG3715	PTS system
EH206_RS11620	COG3716	PTS system mannose fructose sorbose family IID component
EH206_RS11625	COG4811	Protein of unknown function (DUF986)
EH206_RS11630	COG1971	Probably functions as a manganese efflux pump
EH206_RS11635	COG2226	methyltransferase
EH206_RS11650	COG0803	Belongs to the bacterial solute-binding protein 9 family
EH206_RS11655	COG1121	(ABC) transporter
EH206_RS11660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EH206_RS11665	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EH206_RS11670	COG3001	Fructosamine kinase
EH206_RS11680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EH206_RS11685	COG1917	Cupin 2, conserved barrel domain protein
EH206_RS11690	COG1028	Short-chain dehydrogenase reductase Sdr
EH206_RS11705	COG1175	transmembrane transport
EH206_RS11710	COG0395	ABC-type sugar transport system, permease component
EH206_RS11715	COG3842	ATPase activity
EH206_RS11725	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EH206_RS11730	COG1823	symporter activity
EH206_RS11740	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EH206_RS11745	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EH206_RS11750	COG1132	(ABC) transporter
EH206_RS11760	COG0776	regulation of translation
EH206_RS11765	COG0072	phenylalanine-tRNA ligase activity
EH206_RS11765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EH206_RS11770	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EH206_RS11790	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EH206_RS11795	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EH206_RS11800	COG4939	FMN-binding domain protein
EH206_RS11815	COG0823	Involved in the tonB-independent uptake of proteins
EH206_RS11820	COG0501	Belongs to the peptidase M48B family
EH206_RS11825	COG2223	nitrite transmembrane transporter activity
EH206_RS11830	COG3279	Response regulator of the LytR AlgR family
EH206_RS11845	COG1012	belongs to the aldehyde dehydrogenase family
EH206_RS11860	COG0583	DNA-binding transcription factor activity
EH206_RS11865	COG4608	Belongs to the ABC transporter superfamily
EH206_RS11870	COG0444	Belongs to the ABC transporter superfamily
EH206_RS11875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH206_RS11890	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EH206_RS11895	COG1012	belongs to the aldehyde dehydrogenase family
EH206_RS11900	COG0028	Belongs to the TPP enzyme family
EH206_RS11910	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EH206_RS11910	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EH206_RS11920	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EH206_RS11935	COG4598	ABC transporter
EH206_RS11940	COG4160	amino acid transport
EH206_RS11945	COG4215	(ABC) transporter
EH206_RS11950	COG2988	succinylglutamate desuccinylase activity
EH206_RS11955	COG3724	N-succinylarginine dihydrolase activity
EH206_RS11960	COG1012	belongs to the aldehyde dehydrogenase family
EH206_RS11965	COG3138	arginine N-succinyltransferase
EH206_RS11970	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EH206_RS11975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EH206_RS11980	COG2222	sugar isomerase
EH206_RS11990	COG2186	Transcriptional regulator
EH206_RS11995	COG0538	isocitrate dehydrogenase activity
EH206_RS12000	COG1187	pseudouridine synthase activity
EH206_RS12010	COG0482	sulfurtransferase activity
EH206_RS12015	COG2915	High frequency lysogenization protein hflD homolog
EH206_RS12020	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EH206_RS12035	COG2850	peptidyl-arginine hydroxylation
EH206_RS12040	COG2195	Cleaves the N-terminal amino acid of tripeptides
EH206_RS12045	COG3842	ATPase activity
EH206_RS12055	COG1177	transmembrane transport
EH206_RS12060	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EH206_RS12075	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
EH206_RS12080	COG1956	GAF domain-containing protein
EH206_RS12085	COG2995	paraquat-inducible protein a
EH206_RS12090	COG3008	intermembrane lipid transfer
EH206_RS12105	COG1176	ABC-type spermidine putrescine transport system, permease component I
EH206_RS12130	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EH206_RS12130	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EH206_RS12145	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EH206_RS12150	COG2364	Membrane
EH206_RS12155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EH206_RS12315	COG3566	protein conserved in bacteria
EH206_RS12325	COG3567	Phage-associated protein, HI1409 family
EH206_RS12330	COG5410	chromosome segregation
EH206_RS12345	COG3179	chitinase
EH206_RS12365	COG0582	viral genome integration into host DNA
EH206_RS12370	COG1598	PFAM Uncharacterised protein family UPF0150
EH206_RS12375	COG1724	mRNA binding
EH206_RS12485	COG1528	Iron-storage protein
EH206_RS12495	COG1770	oligopeptidase
EH206_RS12500	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EH206_RS12505	COG0800	Aldolase
EH206_RS12510	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EH206_RS12515	COG1737	Transcriptional regulator
EH206_RS12520	COG0469	pyruvate kinase activity
EH206_RS12525	COG1560	Kdo2-lipid A biosynthetic process
EH206_RS12530	COG0739	heme binding
EH206_RS12535	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EH206_RS12540	COG1121	(ABC) transporter
EH206_RS12545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EH206_RS12550	COG2255	four-way junction helicase activity
EH206_RS12555	COG0632	four-way junction helicase activity
EH206_RS12560	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EH206_RS12565	COG0217	transcriptional regulatory protein
EH206_RS12570	COG0494	nUDIX hydrolase
EH206_RS12575	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EH206_RS12580	COG1801	Protein of unknown function DUF72
EH206_RS12585	COG3788	relative of glutathione S-transferase, MAPEG superfamily
EH206_RS12595	COG0500	methyltransferase
EH206_RS12605	COG3142	Participates in the control of copper homeostasis
EH206_RS12610	COG3102	Protein conserved in bacteria
EH206_RS12615	COG0018	arginyl-trna synthetase
EH206_RS12620	COG0728	peptidoglycan biosynthetic process
EH206_RS12625	COG3132	Protein of unknown function, DUF480
EH206_RS12630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EH206_RS12635	COG0477	Major facilitator Superfamily
EH206_RS12640	COG2999	glutathione oxidoreductase activity
EH206_RS12650	COG3381	protein complex oligomerization
EH206_RS12655	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EH206_RS12665	COG2271	Major facilitator Superfamily
EH206_RS12675	COG0246	Mannitol dehydrogenase
EH206_RS12685	COG2186	Transcriptional regulator
EH206_RS12690	COG3130	regulation of translation
EH206_RS12695	COG3009	Protein conserved in bacteria
EH206_RS12700	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EH206_RS12700	COG3008	intermembrane lipid transfer
EH206_RS12705	COG2995	paraquat-inducible protein a
EH206_RS12710	COG0488	(ABC) transporter
EH206_RS12715	COG0116	Belongs to the methyltransferase superfamily
EH206_RS12715	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EH206_RS12720	COG3217	Mosc domain protein beta barrel domain protein
EH206_RS12720	COG0633	Ferredoxin
EH206_RS12730	COG0167	dihydroorotate dehydrogenase activity
EH206_RS12735	COG0308	aminopeptidase N
EH206_RS12740	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EH206_RS12745	COG0017	Asparaginyl-tRNA synthetase
EH206_RS12755	COG1448	Aminotransferase
EH206_RS12770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EH206_RS12775	COG3108	Peptidase M15
EH206_RS12780	COG2989	Protein conserved in bacteria
EH206_RS12785	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EH206_RS12790	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
EH206_RS12795	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
EH206_RS12800	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EH206_RS12805	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EH206_RS12810	COG3173	Aminoglycoside phosphotransferase
EH206_RS12815	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EH206_RS12820	COG2835	tetraacyldisaccharide 4'-kinase activity
EH206_RS12825	COG1663	tetraacyldisaccharide 4'-kinase activity
EH206_RS12830	COG1132	(ABC) transporter
EH206_RS12835	COG0658	competence protein
EH206_RS12835	COG2333	competence protein COMEC
EH206_RS12840	COG2926	Belongs to the UPF0265 family
EH206_RS12845	COG4604	ABC transporter, ATP-binding protein
EH206_RS12850	COG4605	iron ion homeostasis
EH206_RS12860	COG4607	ABC-type enterochelin transport system periplasmic component
EH206_RS12865	COG2925	Exonuclease
EH206_RS12870	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EH206_RS12875	COG0840	transmembrane signaling receptor activity
EH206_RS12880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EH206_RS12890	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EH206_RS12895	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EH206_RS12900	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EH206_RS12905	COG0131	Imidazoleglycerol-phosphate dehydratase
EH206_RS12905	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EH206_RS12910	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EH206_RS12915	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EH206_RS12920	COG0107	imidazoleglycerol-phosphate synthase activity
EH206_RS12925	COG0140	phosphoribosyl-ATP diphosphatase activity
EH206_RS12925	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EH206_RS12930	COG0776	regulation of translation
EH206_RS12935	COG0539	negative regulation of cytoplasmic translation
EH206_RS12940	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EH206_RS12945	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EH206_RS12950	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EH206_RS12955	COG1944	ATP diphosphatase activity
EH206_RS12960	COG2116	formate transmembrane transporter activity
EH206_RS12965	COG1882	Formate acetyltransferase
EH206_RS12970	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EH206_RS13000	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EH206_RS13005	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EH206_RS13010	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EH206_RS13015	COG1674	ftsk spoiiie
EH206_RS13015	COG3107	peptidoglycan biosynthetic process
EH206_RS13025	COG0492	ferredoxin-NADP+ reductase activity
EH206_RS13030	COG4988	ABC transporter
EH206_RS13035	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EH206_RS13040	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EH206_RS13045	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EH206_RS13050	COG0542	response to heat
EH206_RS13055	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EH206_RS13060	COG1278	Cold shock
EH206_RS13065	COG3593	DNA synthesis involved in DNA repair
EH206_RS13070	COG2431	L-lysine efflux transmembrane transporter activity
EH206_RS13075	COG1151	hydroxylamine reductase activity
EH206_RS13080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EH206_RS13085	COG3023	N-Acetylmuramoyl-L-alanine amidase
EH206_RS13090	COG0393	Putative heavy-metal-binding
EH206_RS13095	COG1126	abc transporter atp-binding protein
EH206_RS13100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH206_RS13105	COG4215	(ABC) transporter
EH206_RS13110	COG4160	amino acid transport
EH206_RS13115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH206_RS13120	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EH206_RS13130	COG1177	transmembrane transport
EH206_RS13135	COG1176	ABC-type spermidine putrescine transport system, permease component I
EH206_RS13140	COG3842	ATPase activity
EH206_RS13145	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EH206_RS13155	COG0189	ligase activity
EH206_RS13175	COG0569	domain protein
EH206_RS13175	COG2985	domain, Protein
EH206_RS13180	COG1686	Belongs to the peptidase S11 family
EH206_RS13185	COG2011	ABC-type metal ion transport system permease component
EH206_RS13190	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EH206_RS13195	COG1464	Belongs to the NlpA lipoprotein family
EH206_RS13200	COG0625	glutathione transferase activity
EH206_RS13205	COG2133	pyrroloquinoline quinone binding
EH206_RS13210	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EH206_RS13215	COG2949	membrane
EH206_RS13220	COG2311	Membrane
EH206_RS13225	COG0302	gtp cyclohydrolase
EH206_RS13230	COG0840	transmembrane signaling receptor activity
EH206_RS13235	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EH206_RS13250	COG0371	Dehydrogenase
EH206_RS13255	COG1129	ABC transporter
EH206_RS13260	COG1172	Belongs to the binding-protein-dependent transport system permease family
EH206_RS13265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EH206_RS13270	COG0833	amino acid
EH206_RS13275	COG0583	DNA-binding transcription factor activity
EH206_RS13280	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EH206_RS13285	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EH206_RS13285	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EH206_RS13285	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EH206_RS13290	COG1105	Belongs to the carbohydrate kinase PfkB family
EH206_RS13295	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH206_RS13295	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH206_RS13310	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EH206_RS13315	COG0523	cobalamin synthesis protein
EH206_RS13320	COG0671	phosphoesterase, PA-phosphatase related
EH206_RS13325	COG0791	NLP P60 protein
EH206_RS13330	COG4166	transmembrane transport
EH206_RS13335	COG4174	ABC transporter (Permease)
EH206_RS13340	COG4239	(ABC) transporter, permease
EH206_RS13345	COG4172	Belongs to the ABC transporter superfamily
EH206_RS13365	COG1061	Type III restriction enzyme res subunit
EH206_RS13370	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EH206_RS13375	COG1702	phosphate starvation-inducible protein PhoH
EH206_RS13385	COG1191	sigma factor activity
EH206_RS13390	COG5464	transposase or invertase
EH206_RS13395	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EH206_RS13425	COG1677	Flagellar hook-basal body complex protein FliE
EH206_RS13430	COG1766	The M ring may be actively involved in energy transduction
EH206_RS13440	COG1317	bacterial-type flagellum organization
EH206_RS13495	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EH206_RS13510	COG1706	bacterial-type flagellum-dependent cell motility
EH206_RS13515	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EH206_RS13530	COG1749	Flagellar hook protein flgE
EH206_RS13535	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EH206_RS13540	COG1558	bacterial-type flagellum-dependent cell motility
EH206_RS13545	COG1815	bacterial-type flagellum-dependent cell motility
EH206_RS13555	COG2747	anti-sigma28 factor FlgM
EH206_RS13560	COG3418	PFAM FlgN family protein
EH206_RS13570	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EH206_RS13575	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EH206_RS13585	COG0745	RESPONSE REGULATOR receiver
EH206_RS13590	COG2201	protein-glutamate methylesterase activity
EH206_RS13595	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EH206_RS13600	COG0840	transmembrane signaling receptor activity
EH206_RS13605	COG0840	transmembrane signaling receptor activity
EH206_RS13610	COG0835	chemotaxis
EH206_RS13615	COG2198	Histidine kinase
EH206_RS13615	COG0643	Histidine kinase
EH206_RS13625	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EH206_RS13650	COG0840	transmembrane signaling receptor activity
EH206_RS13655	COG4249	Peptidase C14 caspase catalytic subunit p20
EH206_RS13815	COG0305	Participates in initiation and elongation during chromosome replication
EH206_RS13855	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EH206_RS13895	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EH206_RS13900	COG0322	excinuclease ABC activity
EH206_RS13905	COG2197	response regulator
EH206_RS13920	COG1113	amino acid transport
EH206_RS13950	COG1335	isochorismatase
EH206_RS13960	COG1902	pentaerythritol trinitrate reductase activity
EH206_RS13965	COG3193	protein, possibly involved in utilization of glycolate and propanediol
EH206_RS13970	COG0697	spore germination
EH206_RS13990	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EH206_RS14005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EH206_RS14010	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EH206_RS14020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH206_RS14025	COG0601	transmembrane transport
EH206_RS14030	COG0747	negative chemotaxis
EH206_RS14095	COG2375	cellular response to nickel ion
EH206_RS14105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EH206_RS14110	COG1629	transport
EH206_RS14110	COG4774	siderophore transport
EH206_RS14115	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EH206_RS14120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EH206_RS14125	COG4592	Periplasmic binding protein
EH206_RS14130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EH206_RS14135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EH206_RS14135	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EH206_RS14140	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EH206_RS14140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EH206_RS14160	COG3708	Transcriptional regulator
EH206_RS14160	COG2207	Transcriptional regulator
EH206_RS14170	COG1132	(ABC) transporter
EH206_RS14180	COG0438	transferase activity, transferring glycosyl groups
EH206_RS14200	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EH206_RS14205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EH206_RS14225	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EH206_RS14230	COG1045	serine acetyltransferase
EH206_RS14235	COG0431	NADPH-dependent FMN reductase
EH206_RS14235	COG1053	succinate dehydrogenase
EH206_RS14235	COG3976	FMN-binding domain protein
EH206_RS14255	COG3976	FMN-binding domain protein
EH206_RS14255	COG1053	succinate dehydrogenase
EH206_RS14260	COG0183	Belongs to the thiolase family
EH206_RS14270	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EH206_RS14275	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EH206_RS14280	COG0183	Belongs to the thiolase family
EH206_RS14285	COG3246	L-lysine catabolic process to acetate
EH206_RS14295	COG0583	DNA-binding transcription factor activity
EH206_RS14300	COG2207	Transcriptional regulator
EH206_RS14310	COG2200	EAL domain
EH206_RS14315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH206_RS14320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH206_RS14325	COG1116	anion transmembrane transporter activity
EH206_RS14335	COG0444	Belongs to the ABC transporter superfamily
EH206_RS14355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH206_RS14360	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EH206_RS14375	COG1396	sequence-specific DNA binding
EH206_RS14380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH206_RS14385	COG4215	(ABC) transporter
EH206_RS14400	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EH206_RS14410	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EH206_RS14415	COG1012	belongs to the aldehyde dehydrogenase family
EH206_RS14420	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EH206_RS14425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EH206_RS14430	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EH206_RS14435	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EH206_RS14440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH206_RS14450	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EH206_RS14455	COG0371	Dehydrogenase
EH206_RS14460	COG1301	dicarboxylic acid transport
EH206_RS14465	COG0583	DNA-binding transcription factor activity
EH206_RS14470	COG0697	spore germination
EH206_RS14480	COG0577	efflux transmembrane transporter activity
EH206_RS14480	COG1136	(ABC) transporter
EH206_RS14490	COG1136	(ABC) transporter
EH206_RS14490	COG0577	efflux transmembrane transporter activity
EH206_RS14505	COG0672	)-iron permease
EH206_RS14510	COG0298	carbon dioxide binding
EH206_RS14515	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EH206_RS14520	COG0651	ATP synthesis coupled electron transport
EH206_RS14525	COG0650	Formate hydrogenlyase subunit 4
EH206_RS14530	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EH206_RS14535	COG4237	Hydrogenase 4 membrane
EH206_RS14540	COG0651	ATP synthesis coupled electron transport
EH206_RS14545	COG3261	NADH dehydrogenase
EH206_RS14545	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
EH206_RS14550	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH206_RS14555	COG3260	NADH ubiquinone oxidoreductase 20
EH206_RS14565	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EH206_RS14570	COG0840	transmembrane signaling receptor activity
EH206_RS14580	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EH206_RS14585	COG3383	formate dehydrogenase (NAD+) activity
EH206_RS14590	COG3604	Transcriptional regulator
EH206_RS14595	COG1301	dicarboxylic acid transport
EH206_RS14600	COG0583	DNA-binding transcription factor activity
EH206_RS14620	COG2271	Major facilitator Superfamily
EH206_RS14625	COG1840	ABC-type Fe3 transport system, periplasmic component
EH206_RS14635	COG3842	ATPase activity
EH206_RS14655	COG1917	Cupin 2, conserved barrel domain protein
EH206_RS14655	COG2169	Transcriptional regulator
EH206_RS14660	COG4977	sequence-specific DNA binding
EH206_RS14660	COG1917	Cupin 2, conserved barrel domain protein
EH206_RS14665	COG1070	Carbohydrate kinase
EH206_RS14675	COG1454	alcohol dehydrogenase
EH206_RS14680	COG2814	Major facilitator Superfamily
EH206_RS14700	COG1309	transcriptional regulator
EH206_RS14710	COG2873	o-acetylhomoserine
EH206_RS14715	COG4773	Receptor
EH206_RS14720	COG2814	Major facilitator Superfamily
EH206_RS14735	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EH206_RS14740	COG1984	allophanate hydrolase subunit 2
EH206_RS14750	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EH206_RS14755	COG4221	oxidoreductase activity
EH206_RS14760	COG0765	amino acid transport
EH206_RS14765	COG0765	amino acid transport
EH206_RS14780	COG0641	radical SAM
EH206_RS14790	COG4176	ABC-type proline glycine betaine transport system permease component
EH206_RS14795	COG4175	Glycine betaine
EH206_RS14800	COG0583	DNA-binding transcription factor activity
EH206_RS14805	COG3119	arylsulfatase activity
EH206_RS14815	COG1013	pyruvate-flavodoxin oxidoreductase activity
EH206_RS14820	COG0674	pyruvate-flavodoxin oxidoreductase activity
EH206_RS14845	COG1402	creatininase
EH206_RS14850	COG4172	Belongs to the ABC transporter superfamily
EH206_RS14855	COG0747	negative chemotaxis
EH206_RS14860	COG0601	transmembrane transport
EH206_RS14870	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EH206_RS14880	COG0444	Belongs to the ABC transporter superfamily
EH206_RS14890	COG0601	transmembrane transport
EH206_RS14895	COG0747	negative chemotaxis
EH206_RS14910	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EH206_RS14950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH206_RS14955	COG0765	amino acid transport
EH206_RS14960	COG0765	amino acid transport
EH206_RS14970	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EH206_RS14990	COG3842	ATPase activity
EH206_RS14995	COG1840	ABC-type Fe3 transport system, periplasmic component
EH206_RS15005	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EH206_RS15025	COG3547	Transposase (IS116 IS110 IS902 family)
EH206_RS15035	COG1492	cobalamin metabolic process
EH206_RS15080	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
EH206_RS15090	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EH206_RS15100	COG1064	alcohol dehydrogenase
EH206_RS15105	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EH206_RS15145	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EH206_RS15205	COG0463	Glycosyl transferase, family 2
EH206_RS15225	COG1088	dTDP-glucose 4,6-dehydratase activity
EH206_RS15255	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EH206_RS15260	COG1253	flavin adenine dinucleotide binding
EH206_RS15270	COG5464	transposase or invertase
EH206_RS15275	COG5464	transposase or invertase
EH206_RS15280	COG2982	Protein involved in outer membrane biogenesis
EH206_RS15285	COG0717	Belongs to the dCTP deaminase family
EH206_RS15290	COG0572	uridine kinase
EH206_RS15295	COG0489	protein tyrosine kinase activity
EH206_RS15300	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EH206_RS15300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EH206_RS15315	COG2706	6-phosphogluconolactonase activity
EH206_RS15320	COG0561	phosphatase activity
EH206_RS15325	COG4804	nuclease activity
EH206_RS15330	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EH206_RS15335	COG4149	molybdate abc transporter
EH206_RS15340	COG0725	ABC transporter, periplasmic molybdate-binding protein
EH206_RS15355	COG2005	Transcriptional regulator
EH206_RS15355	COG3585	molybdate ion transport
EH206_RS15360	COG1119	ATPase activity
EH206_RS15365	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EH206_RS15370	COG2017	converts alpha-aldose to the beta-anomer
EH206_RS15390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EH206_RS15395	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EH206_RS15400	COG0588	phosphoglycerate mutase activity
EH206_RS15405	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EH206_RS15415	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EH206_RS15425	COG1811	Na channel or pump
EH206_RS15445	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
EH206_RS15450	COG2885	chlorophyll binding
EH206_RS15455	COG0823	Involved in the tonB-independent uptake of proteins
EH206_RS15460	COG3064	Membrane
EH206_RS15460	COG3064	Membrane
EH206_RS15465	COG0848	biopolymer transport protein
EH206_RS15470	COG0811	peptide transport
EH206_RS15475	COG0824	Thioesterase
EH206_RS15480	COG3790	cyd operon protein YbgE
EH206_RS15485	COG4890	Cyd operon protein YbgT
EH206_RS15490	COG1294	oxidase, subunit
EH206_RS15495	COG1271	oxidase subunit
EH206_RS15500	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EH206_RS15505	COG0045	succinate-CoA ligase (ADP-forming) activity
EH206_RS15510	COG0508	dehydrogenase complex catalyzes the overall conversion of
EH206_RS15515	COG0567	Dehydrogenase, E1 component
EH206_RS15520	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EH206_RS15525	COG1053	succinate dehydrogenase
EH206_RS15530	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EH206_RS15540	COG0372	Belongs to the citrate synthase family
EH206_RS15545	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EH206_RS15550	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EH206_RS15555	COG1984	allophanate hydrolase subunit 2
EH206_RS15560	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EH206_RS15565	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EH206_RS15590	COG0033	Phosphoglucomutase
EH206_RS15595	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
EH206_RS15600	COG0596	Alpha beta hydrolase
EH206_RS15610	COG0840	transmembrane signaling receptor activity
EH206_RS15615	COG0716	FMN binding
EH206_RS15620	COG0735	belongs to the Fur family
EH206_RS15625	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EH206_RS15630	COG1263	PTS System
EH206_RS15630	COG2190	(PTS) system
EH206_RS15630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EH206_RS15635	COG0363	glucosamine-6-phosphate deaminase activity
EH206_RS15640	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EH206_RS15645	COG1940	carbohydrate kinase activity
EH206_RS15645	COG1846	Transcriptional regulator
EH206_RS15650	COG0367	asparagine synthase
EH206_RS15680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EH206_RS15685	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EH206_RS15690	COG1702	phosphate starvation-inducible protein PhoH
EH206_RS15695	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EH206_RS15700	COG4535	Mg2 and Co2 transporter CorC
EH206_RS15705	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EH206_RS15715	COG0765	amino acid transport
EH206_RS15720	COG0765	amino acid transport
EH206_RS15725	COG1126	abc transporter atp-binding protein
EH206_RS15730	COG2888	peptidyl-tyrosine sulfation
EH206_RS15735	COG0495	leucyl-tRNA aminoacylation
EH206_RS15740	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
EH206_RS15745	COG1466	dna polymerase III delta subunit
EH206_RS15750	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EH206_RS15755	COG0799	negative regulation of ribosome biogenesis
EH206_RS15760	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EH206_RS15765	COG0768	penicillin binding
EH206_RS15770	COG0772	Belongs to the SEDS family
EH206_RS15775	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EH206_RS15780	COG1686	Belongs to the peptidase S11 family
EH206_RS15785	COG2921	Belongs to the UPF0250 family
EH206_RS15790	COG0321	lipoyl(octanoyl) transferase activity
EH206_RS15795	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EH206_RS15800	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EH206_RS15810	COG1794	racemase activity, acting on amino acids and derivatives
EH206_RS15820	COG1393	Belongs to the ArsC family
EH206_RS15825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EH206_RS15830	COG1876	peptidase activity
EH206_RS15850	COG4178	(ABC) transporter
EH206_RS15855	COG4774	siderophore transport
EH206_RS15860	COG1595	DNA-templated transcription, initiation
EH206_RS15885	COG0312	modulator of DNA gyrase
EH206_RS15890	COG0312	modulator of DNA gyrase
EH206_RS15895	COG3118	belongs to the thioredoxin family
EH206_RS15900	COG1444	tRNA N-acetyltransferase activity
EH206_RS15905	COG2707	UPF0756 membrane protein
EH206_RS15930	COG0765	amino acid transport
EH206_RS15935	COG0765	amino acid transport
EH206_RS15945	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EH206_RS15950	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
EH206_RS15960	COG2716	regulation of RNA biosynthetic process
EH206_RS15965	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EH206_RS15980	COG4783	chaperone-mediated protein folding
EH206_RS15985	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EH206_RS16000	COG1609	Transcriptional regulator
EH206_RS16010	COG1172	Belongs to the binding-protein-dependent transport system permease family
EH206_RS16020	COG1028	Short-chain dehydrogenase reductase Sdr
EH206_RS16025	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EH206_RS16030	COG2233	PERMEase
EH206_RS16035	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EH206_RS16040	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EH206_RS16045	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EH206_RS16055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EH206_RS16065	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EH206_RS16070	COG4181	ATPase activity
EH206_RS16075	COG2755	lipolytic protein G-D-S-L family
EH206_RS16080	COG0300	oxidoreductase activity
EH206_RS16085	COG3118	belongs to the thioredoxin family
EH206_RS16120	COG1441	menaquinone biosynthetic process
EH206_RS16125	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EH206_RS16130	COG0596	Alpha beta hydrolase
EH206_RS16135	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EH206_RS16140	COG2223	nitrite transmembrane transporter activity
EH206_RS16145	COG2198	Histidine kinase
EH206_RS16145	COG0642	Histidine kinase
EH206_RS16155	COG2205	protein histidine kinase activity
EH206_RS16155	COG0784	Response regulator, receiver
EH206_RS16165	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EH206_RS16175	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EH206_RS16180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EH206_RS16190	COG0154	amidase activity
EH206_RS16200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH206_RS16205	COG1116	anion transmembrane transporter activity
EH206_RS16210	COG0330	HflC and HflK could
EH206_RS16215	COG1585	Membrane protein implicated in regulation of membrane protease activity
EH206_RS16220	COG0183	Belongs to the thiolase family
EH206_RS16225	COG2031	fatty acid transporter
EH206_RS16230	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EH206_RS16235	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EH206_RS16240	COG2204	response regulator
EH206_RS16245	COG3852	Histidine kinase
EH206_RS16275	COG4396	Host-nuclease inhibitor protein Gam
EH206_RS16285	COG3267	Type II secretory pathway component ExeA
EH206_RS16285	COG3409	Peptidoglycan-binding domain 1 protein
EH206_RS16345	COG0741	lytic transglycosylase activity
EH206_RS16370	COG4373	Mu-like prophage FluMu protein gp28
EH206_RS16380	COG2369	cell adhesion
EH206_RS16500	COG0110	maltose O-acetyltransferase activity
EH206_RS16505	COG3423	Transcriptional regulator
EH206_RS16515	COG3735	TraB family
EH206_RS16525	COG0523	cobalamin synthesis protein
EH206_RS16530	COG2879	small protein
EH206_RS16535	COG1966	Carbon starvation protein
EH206_RS16540	COG0583	DNA-binding transcription factor activity
EH206_RS16550	COG0511	ligase activity, forming carbon-carbon bonds
EH206_RS16565	COG1984	allophanate hydrolase subunit 2
EH206_RS16590	COG0737	Belongs to the 5'-nucleotidase family
EH206_RS16595	COG4651	solute:proton antiporter activity
EH206_RS16595	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EH206_RS16605	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EH206_RS16610	COG0563	adenylate kinase activity
EH206_RS16620	COG0326	Molecular chaperone. Has ATPase activity
EH206_RS16630	COG2190	(PTS) system
EH206_RS16630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EH206_RS16630	COG1263	PTS System
EH206_RS16635	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EH206_RS16640	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EH206_RS16650	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EH206_RS16655	COG2832	Protein of unknown function (DUF454)
EH206_RS16670	COG1309	transcriptional regulator
EH206_RS16675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EH206_RS16680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EH206_RS16685	COG0254	rRNA binding
EH206_RS16690	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EH206_RS16710	COG3695	enzyme binding
EH206_RS16715	COG3126	Type III secretion system lipoprotein chaperone (YscW)
EH206_RS16720	COG1946	Acyl-CoA thioesterase
EH206_RS16725	COG0004	ammonium transporteR
EH206_RS16730	COG0347	Belongs to the P(II) protein family
EH206_RS16735	COG1132	(ABC) transporter
EH206_RS16740	COG1132	(ABC) transporter
EH206_RS16745	COG1522	sequence-specific DNA binding
EH206_RS16755	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EH206_RS16760	COG0824	Thioesterase
EH206_RS16765	COG1555	photosystem II stabilization
EH206_RS16770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EH206_RS16775	COG0776	regulation of translation
EH206_RS16785	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EH206_RS16790	COG0740	serine-type endopeptidase activity
EH206_RS16795	COG0544	peptidyl-prolyl cis-trans isomerase activity
EH206_RS16805	COG0271	Belongs to the BolA IbaG family
EH206_RS16810	COG3056	Lipoprotein
EH206_RS16815	COG2223	nitrite transmembrane transporter activity
EH206_RS16820	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EH206_RS16825	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EH206_RS16830	COG1845	cytochrome c oxidase, subunit III
EH206_RS16835	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EH206_RS16840	COG0109	protoheme IX farnesyltransferase activity
EH206_RS16845	COG2814	Major facilitator Superfamily
EH206_RS16890	COG1666	GTP binding
EH206_RS16895	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EH206_RS16900	COG0693	protein deglycase activity
EH206_RS16910	COG1177	transmembrane transport
EH206_RS16915	COG1176	ABC-type spermidine putrescine transport system, permease component I
EH206_RS16920	COG3842	ATPase activity
EH206_RS16925	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EH206_RS16935	COG0301	tRNA thio-modification
EH206_RS16935	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EH206_RS16940	COG1722	exodeoxyribonuclease VII activity
EH206_RS16945	COG0142	geranyltranstransferase activity
EH206_RS16950	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EH206_RS16955	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EH206_RS16960	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EH206_RS16965	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EH206_RS16970	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EH206_RS16975	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EH206_RS16975	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EH206_RS16990	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EH206_RS16995	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EH206_RS17000	COG1862	Preprotein translocase
EH206_RS17005	COG0343	queuine tRNA-ribosyltransferase activity
EH206_RS17010	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EH206_RS17015	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
EH206_RS17020	COG0450	alkyl hydroperoxide reductase
EH206_RS17025	COG0668	transmembrane transport
EH206_RS17040	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EH206_RS17055	COG0420	3'-5' exonuclease activity
EH206_RS17060	COG0419	ATPase involved in DNA repair
EH206_RS17065	COG2974	May be involved in recombination
EH206_RS17075	COG3123	guanosine phosphorylase activity
EH206_RS17080	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EH206_RS17115	COG3706	GGDEF domain
EH206_RS17120	COG2951	lytic endotransglycosylase activity
EH206_RS17125	COG2824	Alkylphosphonate utilization operon protein PhnA
EH206_RS17130	COG0747	negative chemotaxis
EH206_RS17135	COG0601	transmembrane transport
EH206_RS17140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH206_RS17145	COG4172	Belongs to the ABC transporter superfamily
EH206_RS17210	COG4974	Belongs to the 'phage' integrase family
EH206_RS17220	COG4974	Belongs to the 'phage' integrase family
EH206_RS17230	COG0582	viral genome integration into host DNA
EH206_RS17235	COG2003	Belongs to the UPF0758 family
EH206_RS17255	COG3423	Transcriptional regulator
EH206_RS17285	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EH206_RS17295	COG0732	type I restriction modification DNA specificity domain
EH206_RS17300	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EH206_RS17320	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EH206_RS17330	COG3436	PFAM IS66 Orf2 family protein
EH206_RS17370	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EH206_RS17375	COG3015	lipoprotein NlpE involved in copper resistance
EH206_RS17380	COG4681	YaeQ
EH206_RS17390	COG4568	rho-dependent transcription termination
EH206_RS17395	COG0037	tRNA processing
EH206_RS17400	COG0346	lactoylglutathione lyase activity
EH206_RS17405	COG0825	malonyl-CoA metabolic process
EH206_RS17415	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EH206_RS17420	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EH206_RS17425	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EH206_RS17430	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EH206_RS17435	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EH206_RS17440	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
EH206_RS17445	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EH206_RS17450	COG0750	zinc metalloprotease
EH206_RS17455	COG0575	Belongs to the CDS family
EH206_RS17460	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EH206_RS17465	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EH206_RS17470	COG0233	cytoplasmic translational termination
EH206_RS17480	COG0528	UMP kinase activity
EH206_RS17490	COG0052	Belongs to the universal ribosomal protein uS2 family
EH206_RS17500	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EH206_RS17505	COG2171	N-acyltransferase activity
EH206_RS17535	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EH206_RS17535	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EH206_RS17540	COG1611	Belongs to the LOG family
EH206_RS17545	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EH206_RS17550	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
EH206_RS17555	COG2363	Small membrane protein
EH206_RS17560	COG0583	DNA-binding transcription factor activity
EH206_RS17570	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EH206_RS17575	COG2166	iron-sulfur cluster assembly
EH206_RS17580	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EH206_RS17600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH206_RS17605	COG4172	Belongs to the ABC transporter superfamily
EH206_RS17610	COG1028	Short-chain dehydrogenase reductase Sdr
EH206_RS17615	COG1473	amidohydrolase
EH206_RS17620	COG1309	transcriptional regulator
EH206_RS17625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EH206_RS17630	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EH206_RS17645	COG0860	N-Acetylmuramoyl-L-alanine amidase
EH206_RS17650	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EH206_RS17650	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EH206_RS17655	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EH206_RS17660	COG1074	ATP-dependent DNA helicase activity
EH206_RS17665	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EH206_RS17670	COG1025	Belongs to the peptidase M16 family
EH206_RS17690	COG2165	general secretion pathway protein
EH206_RS17695	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EH206_RS17700	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EH206_RS17710	COG0494	nUDIX hydrolase
EH206_RS17715	COG3066	DNA modification
EH206_RS17720	COG0861	Integral membrane protein TerC family
EH206_RS17730	COG0667	Aldo Keto reductase
EH206_RS17740	COG3171	Protein conserved in bacteria
EH206_RS17745	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EH206_RS17755	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
EH206_RS17760	COG0741	lytic transglycosylase activity
EH206_RS17775	COG1309	transcriptional regulator
EH206_RS17790	COG1113	amino acid transport
EH206_RS17795	COG1982	Orn Lys Arg decarboxylase major
EH206_RS17810	COG0582	viral genome integration into host DNA
EH206_RS17830	COG3423	Transcriptional regulator
EH206_RS17875	COG0251	oxidation-reduction process
EH206_RS17895	COG0583	DNA-binding transcription factor activity
EH206_RS17900	COG0473	3-isopropylmalate dehydrogenase activity
EH206_RS17910	COG1802	Transcriptional regulator
EH206_RS17915	COG0246	Mannitol dehydrogenase
EH206_RS17920	COG0477	Major facilitator Superfamily
EH206_RS17925	COG1063	alcohol dehydrogenase
EH206_RS17930	COG4948	Mandelate Racemase Muconate Lactonizing
EH206_RS17935	COG0437	4 iron, 4 sulfur cluster binding
EH206_RS17940	COG3301	Polysulphide reductase, NrfD
EH206_RS17945	COG0477	Major facilitator Superfamily
EH206_RS17950	COG3145	DNA-N1-methyladenine dioxygenase activity
EH206_RS17955	COG2169	Transcriptional regulator
EH206_RS17955	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EH206_RS17975	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EH206_RS17975	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EH206_RS17985	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EH206_RS17995	COG0531	amino acid
EH206_RS18000	COG3115	cell septum assembly
EH206_RS18005	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
EH206_RS18015	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH206_RS18025	COG2190	(PTS) system
EH206_RS18030	COG2205	protein histidine kinase activity
EH206_RS18035	COG0745	RESPONSE REGULATOR receiver
EH206_RS18040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EH206_RS18045	COG0577	efflux transmembrane transporter activity
EH206_RS18045	COG1136	(ABC) transporter
EH206_RS18055	COG4208	sulfate ABC transporter
EH206_RS18060	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EH206_RS18065	COG4150	thiosulfate binding
EH206_RS18070	COG2837	iron assimilation
EH206_RS18080	COG0456	acetyltransferase
EH206_RS18085	COG0408	coproporphyrinogen oxidase activity
EH206_RS18090	COG1671	Belongs to the UPF0178 family
EH206_RS18095	COG0280	phosphate acetyltransferase
EH206_RS18095	COG0281	malic enzyme
EH206_RS18100	COG0494	nUDIX hydrolase
EH206_RS18105	COG1914	H( )-stimulated, divalent metal cation uptake system
EH206_RS18110	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EH206_RS18115	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EH206_RS18120	COG0497	DNA recombination
EH206_RS18130	COG2914	Belongs to the UPF0125 (RnfH) family
EH206_RS18135	COG2867	negative regulation of translational initiation
EH206_RS18140	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EH206_RS18155	COG2999	glutathione oxidoreductase activity
EH206_RS18170	COG1053	succinate dehydrogenase
EH206_RS18180	COG1013	pyruvate-flavodoxin oxidoreductase activity
EH206_RS18180	COG0674	pyruvate-flavodoxin oxidoreductase activity
EH206_RS18180	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EH206_RS18180	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH206_RS18185	COG2944	sequence-specific DNA binding
EH206_RS18200	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EH206_RS18210	COG0765	amino acid transport
EH206_RS18220	COG1376	ErfK ybiS ycfS ynhG family protein
EH206_RS18235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EH206_RS18320	COG4964	Belongs to the GSP D family
EH206_RS18340	COG2205	protein histidine kinase activity
EH206_RS18350	COG0025	NhaP-type Na H and K H
EH206_RS18355	COG2252	PERMEase
EH206_RS18360	COG1560	Kdo2-lipid A biosynthetic process
EH206_RS18365	COG1278	Cold shock
EH206_RS18375	COG2200	EAL domain
EH206_RS18380	COG1105	Belongs to the carbohydrate kinase PfkB family
EH206_RS18390	COG0484	heat shock protein binding
EH206_RS18405	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EH206_RS18410	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EH206_RS18420	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EH206_RS18425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EH206_RS18430	COG4974	Belongs to the 'phage' integrase family
EH206_RS18435	COG0477	Major facilitator Superfamily
EH206_RS18440	COG0716	FMN binding
EH206_RS18445	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
EH206_RS18455	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EH206_RS18460	COG0354	folic acid binding
EH206_RS18475	COG1272	protein, Hemolysin III
EH206_RS18495	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EH206_RS18505	COG1175	transmembrane transport
EH206_RS18510	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EH206_RS18510	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EH206_RS18515	COG0509	glycine decarboxylation via glycine cleavage system
EH206_RS18520	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EH206_RS18530	COG4114	ferric iron reductase
EH206_RS18575	COG0656	L-ascorbic acid biosynthetic process
EH206_RS18580	COG2813	Specifically methylates the guanine in position
EH206_RS18585	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
EH206_RS18610	COG0813	purine-nucleoside phosphorylase activity
EH206_RS18615	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EH206_RS18620	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EH206_RS18635	COG2827	Endonuclease containing a URI domain
EH206_RS18640	COG3153	acetyltransferase
EH206_RS18645	COG3154	lipid carrier protein
EH206_RS18650	COG0826	peptidase U32
EH206_RS18655	COG0826	peptidase U32
EH206_RS18675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EH206_RS18680	COG0513	Belongs to the DEAD box helicase family
EH206_RS18695	COG1185	polyribonucleotide nucleotidyltransferase activity
EH206_RS18700	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EH206_RS18705	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EH206_RS18710	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EH206_RS18715	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EH206_RS18720	COG0195	Participates in both transcription termination and antitermination
EH206_RS18725	COG0779	Required for maturation of 30S ribosomal subunits
EH206_RS18760	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EH206_RS18765	COG0435	Glutathione S-transferase
EH206_RS18770	COG4771	TonB-dependent receptor
EH206_RS18775	COG2814	Major facilitator Superfamily
EH206_RS18795	COG0515	serine threonine protein kinase
EH206_RS18800	COG2194	sulfuric ester hydrolase activity
EH206_RS18815	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EH206_RS18820	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EH206_RS18825	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EH206_RS18830	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EH206_RS18835	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EH206_RS18840	COG1534	Rna-binding protein
EH206_RS18850	COG2027	D-alanyl-D-alanine carboxypeptidase
EH206_RS18855	COG1953	Uracil, thiamine, allantoin
EH206_RS18875	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EH206_RS18880	COG0697	spore germination
EH206_RS18890	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EH206_RS18895	COG0142	geranyltranstransferase activity
EH206_RS18910	COG3423	Transcriptional regulator
EH206_RS18915	COG0039	L-malate dehydrogenase activity
EH206_RS18920	COG1438	arginine binding
EH206_RS18925	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EH206_RS18935	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EH206_RS18940	COG0358	DNA primase activity
EH206_RS18950	COG3663	DNA glycosylase
EH206_RS19030	COG3678	ATP-independent chaperone mediated protein folding
EH206_RS19040	COG0446	pyridine nucleotide-disulphide oxidoreductase
EH206_RS19040	COG1902	pentaerythritol trinitrate reductase activity
EH206_RS19045	COG2813	Specifically methylates the guanine in position
EH206_RS19050	COG0861	Integral membrane protein TerC family
EH206_RS19055	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EH206_RS19065	COG0246	Mannitol dehydrogenase
EH206_RS19080	COG0586	Pfam SNARE associated Golgi protein
EH206_RS19095	COG4575	ribosome binding
EH206_RS19100	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
EH206_RS19110	COG2259	Doxx family
EH206_RS19115	COG0435	Glutathione S-transferase
EH206_RS19120	COG0583	DNA-binding transcription factor activity
EH206_RS19125	COG1741	Belongs to the pirin family
EH206_RS19130	COG0735	belongs to the Fur family
EH206_RS19135	COG3237	CsbD-like
EH206_RS19140	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EH206_RS19145	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EH206_RS19150	COG2937	Belongs to the GPAT DAPAT family
EH206_RS19155	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EH206_RS19160	COG3161	chorismate lyase activity
EH206_RS19165	COG0459	protein refolding
EH206_RS19170	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EH206_RS19185	COG1324	tolerance protein
EH206_RS19190	COG4232	protein-disulfide reductase activity
EH206_RS19195	COG1309	transcriptional regulator
EH206_RS19265	COG3423	Transcriptional regulator
EH206_RS19295	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EH206_RS19325	COG4735	regulation of single-species biofilm formation
EH206_RS19330	COG3436	PFAM IS66 Orf2 family protein
EH206_RS19495	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EH206_RS19555	COG0582	viral genome integration into host DNA
EH206_RS19575	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
EH206_RS19580	COG3423	Transcriptional regulator
EH206_RS19620	COG0577	efflux transmembrane transporter activity
EH206_RS19620	COG1136	(ABC) transporter
EH206_RS19700	COG0583	DNA-binding transcription factor activity
EH206_RS19705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EH206_RS19750	COG0604	alcohol dehydrogenase
EH206_RS19765	COG2963	transposase activity
EH206_RS19800	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EH206_RS19805	COG0673	inositol 2-dehydrogenase activity
EH206_RS19820	COG1621	beta-fructofuranosidase activity
EH206_RS19845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EH206_RS19850	COG0084	hydrolase, TatD family'
EH206_RS19860	COG5487	UPF0391 membrane protein
EH206_RS19865	COG2823	Periplasmic or secreted lipoprotein
EH206_RS19870	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EH206_RS19875	COG1028	Short-chain dehydrogenase reductase Sdr
EH206_RS19880	COG3433	isochorismatase activity
EH206_RS19880	COG1535	isochorismatase
EH206_RS19885	COG1021	2,3-dihydroxybenzoate-AMP ligase
EH206_RS19890	COG1169	isochorismate synthase
EH206_RS19895	COG4774	siderophore transport
EH206_RS19900	COG2382	esterase
EH206_RS19915	COG1120	ATPase activity
EH206_RS19920	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EH206_RS19925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EH206_RS19930	COG0477	Major facilitator Superfamily
EH206_RS19935	COG4592	Periplasmic binding protein
EH206_RS19940	COG3726	membrane protein affecting hemolysin expression
EH206_RS19945	COG0560	Phosphoserine phosphatase
EH206_RS19960	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EH206_RS19970	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EH206_RS19975	COG3079	Belongs to the UPF0149 family
EH206_RS19980	COG0006	proline dipeptidase activity
EH206_RS19985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EH206_RS19990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EH206_RS19995	COG2130	NADP-dependent
EH206_RS20005	COG1169	isochorismate synthase
EH206_RS20010	COG3477	response to acidic pH
EH206_RS20015	COG0747	negative chemotaxis
EH206_RS20020	COG0601	transmembrane transport
EH206_RS20025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH206_RS20040	COG3254	rhamnose metabolic process
EH206_RS20050	COG1124	(ABC) transporter
EH206_RS20055	COG0444	Belongs to the ABC transporter superfamily
EH206_RS20065	COG0601	transmembrane transport
EH206_RS20070	COG0747	negative chemotaxis
EH206_RS20075	COG2831	hemolysin activation secretion protein
EH206_RS20080	COG0456	acetyltransferase
EH206_RS20085	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
EH206_RS20090	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EH206_RS20100	COG2731	YhcH YjgK YiaL family protein
EH206_RS20110	COG0540	Belongs to the ATCase OTCase family
EH206_RS20115	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
EH206_RS20125	COG2308	Evidence 4 Homologs of previously reported genes of
EH206_RS20145	COG4172	Belongs to the ABC transporter superfamily
EH206_RS20150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH206_RS20165	COG1328	CTP reductase activity
EH206_RS20170	COG0602	queuosine metabolic process
EH206_RS20175	COG0702	epimerase
EH206_RS20190	COG2814	Major facilitator Superfamily
EH206_RS20200	COG4115	mRNA cleavage
EH206_RS20205	COG2161	toxin-antitoxin pair type II binding
EH206_RS20210	COG1203	CRISPR-associated helicase, Cas3
EH206_RS20245	COG0848	biopolymer transport protein
EH206_RS20250	COG0811	peptide transport
EH206_RS20255	COG0525	valine-tRNA ligase activity
EH206_RS20260	COG2927	DNA polymerase III (CHI subunit)
EH206_RS20265	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EH206_RS20270	COG0795	lipopolysaccharide-transporting ATPase activity
EH206_RS20275	COG0795	lipopolysaccharide-transporting ATPase activity
EH206_RS20285	COG0582	viral genome integration into host DNA
EH206_RS20290	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EH206_RS20360	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EH206_RS20365	COG0514	ATP-dependent DNA helicase (RecQ)
EH206_RS20400	COG0720	synthase
EH206_RS20420	COG0582	viral genome integration into host DNA
EH206_RS20455	COG1070	Carbohydrate kinase
EH206_RS20460	COG1028	Short-chain dehydrogenase reductase Sdr
EH206_RS20465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EH206_RS20470	COG3775	system Galactitol-specific IIC component
EH206_RS20480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EH206_RS20480	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
EH206_RS20490	COG0583	DNA-binding transcription factor activity
EH206_RS20500	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EH206_RS20505	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EH206_RS20525	COG0656	L-ascorbic acid biosynthetic process
EH206_RS20540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EH206_RS20545	COG2132	Multicopper oxidase
EH206_RS20550	COG0204	Acyl-transferase
EH206_RS20555	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EH206_RS20565	COG0318	PFAM AMP-dependent synthetase and ligase
EH206_RS20570	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EH206_RS20585	COG4521	taurine ABC transporter
EH206_RS20590	COG1116	anion transmembrane transporter activity
EH206_RS20595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH206_RS20600	COG0187	DNA topoisomerase II activity
EH206_RS20605	COG3150	esterase
EH206_RS20610	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EH206_RS20615	COG3151	Protein conserved in bacteria
EH206_RS20620	COG0494	nUDIX hydrolase
EH206_RS20625	COG1538	Outer membrane efflux protein
EH206_RS20630	COG5463	Belongs to the UPF0441 family
EH206_RS20635	COG0754	glutathionylspermidine amidase activity
EH206_RS20640	COG3384	dioxygenase
EH206_RS20650	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EH206_RS20655	COG3107	peptidoglycan biosynthetic process
EH206_RS20660	COG0792	nuclease activity
EH206_RS20665	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EH206_RS20670	COG2823	Periplasmic or secreted lipoprotein
EH206_RS20675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EH206_RS20680	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EH206_RS20685	COG0784	Response regulator, receiver
EH206_RS20685	COG2198	Histidine kinase
EH206_RS20685	COG5002	protein histidine kinase activity
EH206_RS20690	COG1242	4 iron, 4 sulfur cluster binding
EH206_RS20695	COG0067	glutamate synthase
EH206_RS20695	COG0070	glutamate synthase
EH206_RS20695	COG0069	glutamate synthase activity
EH206_RS20700	COG0493	'glutamate synthase
EH206_RS20720	COG2271	Major facilitator Superfamily
EH206_RS20725	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EH206_RS20735	COG2969	positive regulation of protein catabolic process
EH206_RS20740	COG0625	glutathione transferase activity
EH206_RS20745	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EH206_RS20750	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EH206_RS20760	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EH206_RS20765	COG3105	Protein conserved in bacteria
EH206_RS20770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EH206_RS20775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EH206_RS20780	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EH206_RS20785	COG5007	Belongs to the BolA IbaG family
EH206_RS20790	COG3113	response to antibiotic
EH206_RS20795	COG2854	intermembrane phospholipid transfer
EH206_RS20800	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EH206_RS20805	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EH206_RS20810	COG1127	ABC transporter
EH206_RS20815	COG0530	calcium, potassium:sodium antiporter activity
EH206_RS20820	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EH206_RS20820	COG0517	IMP dehydrogenase activity
EH206_RS20825	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EH206_RS20830	COG3117	lipopolysaccharide transmembrane transporter activity
EH206_RS20835	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EH206_RS20840	COG1137	ATPase activity
EH206_RS20845	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EH206_RS20850	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EH206_RS20855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH206_RS20860	COG1660	Displays ATPase and GTPase activities
EH206_RS20865	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH206_RS20870	COG0312	modulator of DNA gyrase
EH206_RS20885	COG3028	Belongs to the UPF0307 family
EH206_RS20890	COG0312	modulator of DNA gyrase
EH206_RS20895	COG3164	Protein of unknown function
EH206_RS20900	COG1530	ribonuclease E activity
EH206_RS20905	COG0424	maF-like protein
EH206_RS20910	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EH206_RS20915	COG1792	Involved in formation and maintenance of cell shape
EH206_RS20920	COG1077	Cell shape determining protein MreB Mrl
EH206_RS20925	COG2199	diguanylate cyclase activity
EH206_RS20925	COG2200	EAL domain
EH206_RS20930	COG0604	alcohol dehydrogenase
EH206_RS20935	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EH206_RS20940	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
EH206_RS20945	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EH206_RS20950	COG0511	ligase activity, forming carbon-carbon bonds
EH206_RS20955	COG0439	Biotin carboxylase
EH206_RS20960	COG3924	membrane
EH206_RS20965	COG4145	pantothenate transmembrane transporter activity
EH206_RS20970	COG2264	protein methyltransferase activity
EH206_RS20980	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EH206_RS20985	COG4771	TonB-dependent receptor
EH206_RS20990	COG2205	protein histidine kinase activity
EH206_RS21000	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EH206_RS21005	COG3730	PTS system glucitol sorbitol-specific
EH206_RS21020	COG1028	Short-chain dehydrogenase reductase Sdr
EH206_RS21030	COG1349	DNA-binding transcription factor activity
EH206_RS21035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH206_RS21040	COG0765	amino acid transport
EH206_RS21075	COG0138	bifunctional purine biosynthesis protein purh
EH206_RS21080	COG0151	Belongs to the GarS family
EH206_RS21100	COG1515	deoxyribonuclease V activity
EH206_RS21105	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EH206_RS21110	COG2816	NAD+ diphosphatase activity
EH206_RS21115	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
EH206_RS21120	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EH206_RS21125	COG0352	thiamine-phosphate diphosphorylase activity
EH206_RS21130	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EH206_RS21135	COG2104	thiamine diphosphate biosynthetic process
EH206_RS21140	COG2022	thiamine diphosphate biosynthetic process
EH206_RS21150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EH206_RS21155	COG5457	Domain of unknown function (DUF1127)
EH206_RS21160	COG0477	Major facilitator Superfamily
EH206_RS21165	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EH206_RS21170	COG0085	RNA polymerase activity
EH206_RS21180	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EH206_RS21185	COG0081	regulation of translation
EH206_RS21190	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EH206_RS21195	COG0250	Participates in transcription elongation, termination and antitermination
EH206_RS21240	COG1072	(Pantothenic acid kinase))
EH206_RS21245	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EH206_RS21245	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EH206_RS21250	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EH206_RS21275	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EH206_RS21285	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EH206_RS21300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EH206_RS21320	COG0527	aspartate kinase activity
EH206_RS21320	COG0460	homoserine dehydrogenase
EH206_RS21325	COG0626	cystathionine gamma-synthase activity
EH206_RS21330	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
EH206_RS21335	COG0254	rRNA binding
EH206_RS21340	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EH206_RS21345	COG1609	Transcriptional regulator
EH206_RS21350	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EH206_RS21355	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EH206_RS21360	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EH206_RS21365	COG1575	Belongs to the MenA family. Type 1 subfamily
EH206_RS21370	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EH206_RS21375	COG3074	FtsZ-dependent cytokinesis
EH206_RS21380	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EH206_RS21385	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EH206_RS21400	COG1494	fructose-1,6-bisphosphatase
EH206_RS21410	COG3152	Membrane
EH206_RS21420	COG0149	triose-phosphate isomerase activity
EH206_RS21425	COG2957	Belongs to the agmatine deiminase family
EH206_RS21445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH206_RS21485	COG0583	DNA-binding transcription factor activity
EH206_RS21490	COG0205	6-phosphofructokinase activity
EH206_RS21495	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EH206_RS21500	COG2814	Major facilitator Superfamily
EH206_RS21510	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EH206_RS21515	COG0425	Belongs to the sulfur carrier protein TusA family
EH206_RS21525	COG3714	YhhN family
EH206_RS21535	COG3776	membrane
EH206_RS21540	COG0742	ribosomal rna small subunit methyltransferase
EH206_RS21545	COG0552	protein localization to endoplasmic reticulum
EH206_RS21545	COG0552	protein localization to endoplasmic reticulum
EH206_RS21550	COG2884	Cell division ATP-binding protein ftsE
EH206_RS21555	COG2177	Part of the ABC transporter FtsEX involved in
EH206_RS21565	COG0456	acetyltransferase
EH206_RS21580	COG0559	Belongs to the binding-protein-dependent transport system permease family
EH206_RS21585	COG4177	L-phenylalanine transmembrane transporter activity
EH206_RS21590	COG0411	ABC transporter
EH206_RS21600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EH206_RS21605	COG0840	transmembrane signaling receptor activity
EH206_RS21610	COG2610	gluconate transmembrane transporter activity
EH206_RS21615	COG3622	Belongs to the hyi family
EH206_RS21620	COG0235	Class ii aldolase
EH206_RS21625	COG3395	kinase activity
EH206_RS21630	COG2084	Dehydrogenase
EH206_RS21635	COG1349	DNA-binding transcription factor activity
EH206_RS21650	COG3311	Transcriptional regulator
EH206_RS21655	COG1653	transport
EH206_RS21660	COG1175	transmembrane transport
EH206_RS21665	COG0395	ABC-type sugar transport system, permease component
EH206_RS21670	COG3842	ATPase activity
EH206_RS21675	COG0584	glycerophosphoryl diester phosphodiesterase
EH206_RS21690	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EH206_RS21695	COG2205	protein histidine kinase activity
EH206_RS21700	COG0745	RESPONSE REGULATOR receiver
EH206_RS21705	COG3678	ATP-independent chaperone mediated protein folding
EH206_RS21755	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EH206_RS21800	COG4695	Portal protein
EH206_RS21950	COG1053	succinate dehydrogenase
EH206_RS21955	COG1295	ribonuclease BN
EH206_RS21960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EH206_RS21965	COG0612	Peptidase, M16
EH206_RS21970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EH206_RS21975	COG1301	dicarboxylic acid transport
EH206_RS21980	COG2200	EAL domain
EH206_RS21980	COG2199	diguanylate cyclase activity
EH206_RS21985	COG4608	Belongs to the ABC transporter superfamily
EH206_RS21990	COG0444	Belongs to the ABC transporter superfamily
EH206_RS21995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH206_RS22000	COG0601	transmembrane transport
EH206_RS22005	COG0747	negative chemotaxis
EH206_RS22010	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
EH206_RS22020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH206_RS22025	COG0765	amino acid transport
EH206_RS22030	COG0765	amino acid transport
EH206_RS22040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EH206_RS22060	COG3845	ABC transporter
EH206_RS22065	COG4603	Belongs to the binding-protein-dependent transport system permease family
EH206_RS22070	COG1079	Belongs to the binding-protein-dependent transport system permease family
EH206_RS22085	COG2271	Major facilitator Superfamily
EH206_RS22090	COG4948	Mandelate Racemase Muconate Lactonizing
EH206_RS22095	COG1802	Transcriptional regulator
EH206_RS22100	COG1063	alcohol dehydrogenase
EH206_RS22120	COG0747	negative chemotaxis
EH206_RS22130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH206_RS22135	COG4172	Belongs to the ABC transporter superfamily
EH206_RS22140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EH206_RS22150	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EH206_RS22165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EH206_RS22170	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EH206_RS22180	COG0742	ribosomal rna small subunit methyltransferase
EH206_RS22190	COG0589	response to stress
EH206_RS22200	COG0306	phosphate transporter
EH206_RS22205	COG2081	HI0933 family
EH206_RS22225	COG2194	sulfuric ester hydrolase activity
EH206_RS22230	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EH206_RS22235	COG0194	GDP metabolic process
EH206_RS22240	COG1758	RNA polymerase activity
EH206_RS22245	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EH206_RS22250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EH206_RS22255	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EH206_RS22260	COG2233	PERMEase
EH206_RS22265	COG2982	Protein involved in outer membrane biogenesis
EH206_RS22270	COG0456	acetyltransferase
EH206_RS22275	COG1490	D-aminoacyl-tRNA deacylase activity
EH206_RS22280	COG1011	Hydrolase
EH206_RS22290	COG0174	glutamine synthetase
EH206_RS22295	COG3852	Histidine kinase
EH206_RS22320	COG3078	GTPase activator activity
EH206_RS22325	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EH206_RS22330	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EH206_RS22330	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EH206_RS22340	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EH206_RS22345	COG3084	Protein conserved in bacteria
EH206_RS22350	COG0746	molybdenum cofactor guanylyltransferase activity
EH206_RS22355	COG1763	Mo-molybdopterin cofactor biosynthetic process
EH206_RS22380	COG1609	Transcriptional regulator
EH206_RS22385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EH206_RS22395	COG1172	Belongs to the binding-protein-dependent transport system permease family
EH206_RS22400	COG1129	ABC transporter
EH206_RS22405	COG1869	D-ribose catabolic process
EH206_RS22410	COG3111	PFAM Bacterial OB fold (BOF) protein
EH206_RS22425	COG3158	transport of potassium into the cell
EH206_RS22430	COG0714	Associated with various cellular activities
EH206_RS22440	COG1522	sequence-specific DNA binding
EH206_RS22445	COG0716	FMN binding
EH206_RS22450	COG0445	tRNA wobble uridine modification
EH206_RS22455	COG0357	Ribosomal RNA small subunit methyltransferase G
EH206_RS22460	COG3312	ion transport
EH206_RS22465	COG0356	it plays a direct role in the translocation of protons across the membrane
EH206_RS22475	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EH206_RS22480	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EH206_RS22485	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EH206_RS22490	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EH206_RS22495	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EH206_RS22500	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EH206_RS22505	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EH206_RS22510	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EH206_RS22540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EH206_RS22550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EH206_RS22585	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EH206_RS22595	COG1028	Short-chain dehydrogenase reductase Sdr
EH206_RS22605	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EH206_RS22610	COG0573	inorganic phosphate transmembrane transporter activity
EH206_RS22615	COG0581	inorganic phosphate transmembrane transporter activity
EH206_RS22620	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EH206_RS22640	COG0747	negative chemotaxis
EH206_RS22645	COG0601	transmembrane transport
EH206_RS22650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH206_RS22655	COG0444	Belongs to the ABC transporter superfamily
EH206_RS22680	COG1522	sequence-specific DNA binding
EH206_RS22700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH206_RS22710	COG0765	amino acid transport
EH206_RS22715	COG2252	PERMEase
EH206_RS22720	COG2091	lysine biosynthetic process via aminoadipic acid
EH206_RS22725	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EH206_RS22730	COG0493	'glutamate synthase
EH206_RS22730	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EH206_RS22735	COG1764	response to oxidative stress
EH206_RS22740	COG1733	regulation of RNA biosynthetic process
EH206_RS22745	COG0702	epimerase
EH206_RS22750	COG2233	PERMEase
EH206_RS22755	COG2351	hydroxyisourate hydrolase activity
EH206_RS22765	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EH206_RS22775	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EH206_RS22785	COG0402	S-adenosylhomocysteine deaminase activity
EH206_RS22795	COG0765	amino acid transport
EH206_RS22800	COG0765	amino acid transport
EH206_RS22845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EH206_RS22865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH206_RS22870	COG1116	anion transmembrane transporter activity
EH206_RS22875	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH206_RS22880	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EH206_RS22890	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EH206_RS22900	COG2068	MobA-Related Protein
EH206_RS22905	COG3829	transcription factor binding
EH206_RS22910	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EH206_RS22920	COG3608	succinylglutamate desuccinylase aspartoacylase
EH206_RS22920	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EH206_RS22925	COG0493	'glutamate synthase
EH206_RS22925	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EH206_RS22930	COG0402	S-adenosylhomocysteine deaminase activity
EH206_RS22940	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EH206_RS22960	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EH206_RS22965	COG0706	membrane insertase activity
EH206_RS22975	COG0594	ribonuclease P activity
EH206_RS22980	COG0230	Belongs to the bacterial ribosomal protein bL34 family