locus-tag	class	description
FPS98_RS00020	COG0305	Participates in initiation and elongation during chromosome replication
FPS98_RS00140	COG5518	Phage portal protein
FPS98_RS00150	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FPS98_RS00295	COG1388	LysM domain
FPS98_RS00295	COG0860	N-Acetylmuramoyl-L-alanine amidase
FPS98_RS00300	COG1040	competence protein
FPS98_RS00305	COG0758	DNA mediated transformation
FPS98_RS00335	COG0840	transmembrane signaling receptor activity
FPS98_RS00380	COG0531	amino acid
FPS98_RS00390	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
FPS98_RS00400	COG1595	DNA-templated transcription, initiation
FPS98_RS00420	COG1151	hydroxylamine reductase activity
FPS98_RS00425	COG2223	nitrite transmembrane transporter activity
FPS98_RS00430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FPS98_RS00440	COG0243	molybdopterin cofactor binding
FPS98_RS00495	COG1737	Transcriptional regulator
FPS98_RS00505	COG1175	transmembrane transport
FPS98_RS00510	COG0395	ABC-type sugar transport system, permease component
FPS98_RS00520	COG1472	Belongs to the glycosyl hydrolase 3 family
FPS98_RS00525	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FPS98_RS00555	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FPS98_RS00570	COG2271	Major facilitator Superfamily
FPS98_RS00575	COG1473	amidohydrolase
FPS98_RS00615	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FPS98_RS00625	COG0768	penicillin binding
FPS98_RS00630	COG0768	penicillin binding
FPS98_RS00640	COG0596	Alpha beta hydrolase
FPS98_RS00650	COG5002	protein histidine kinase activity
FPS98_RS00655	COG0745	RESPONSE REGULATOR receiver
FPS98_RS00660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FPS98_RS00670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FPS98_RS00675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPS98_RS00690	COG0697	spore germination
FPS98_RS00695	COG0640	Transcriptional regulator
FPS98_RS00705	COG0739	heme binding
FPS98_RS00710	COG0745	RESPONSE REGULATOR receiver
FPS98_RS00715	COG2205	protein histidine kinase activity
FPS98_RS00720	COG0840	transmembrane signaling receptor activity
FPS98_RS00725	COG0095	Lipoate-protein ligase
FPS98_RS00740	COG0697	spore germination
FPS98_RS00750	COG2207	Transcriptional regulator
FPS98_RS00755	COG0477	Major facilitator Superfamily
FPS98_RS00765	COG1028	Short-chain dehydrogenase reductase Sdr
FPS98_RS00770	COG3135	benzoate transporter
FPS98_RS00775	COG2204	response regulator
FPS98_RS00830	COG1846	Transcriptional regulator
FPS98_RS00845	COG2909	trisaccharide binding
FPS98_RS00860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FPS98_RS00880	COG1309	transcriptional regulator
FPS98_RS00890	COG0747	negative chemotaxis
FPS98_RS00895	COG0601	transmembrane transport
FPS98_RS00905	COG0444	Belongs to the ABC transporter superfamily
FPS98_RS00910	COG4608	Belongs to the ABC transporter superfamily
FPS98_RS00915	COG5583	Uncharacterized small protein (DUF2292)
FPS98_RS00925	COG4166	transmembrane transport
FPS98_RS00935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FPS98_RS00950	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FPS98_RS00965	COG1214	PFAM Peptidase M22, glycoprotease
FPS98_RS00965	COG0456	acetyltransferase
FPS98_RS00970	COG2972	Histidine kinase
FPS98_RS00975	COG4753	response regulator
FPS98_RS00975	COG2207	Transcriptional regulator
FPS98_RS00990	COG1175	transmembrane transport
FPS98_RS00995	COG0395	ABC-type sugar transport system, permease component
FPS98_RS01000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FPS98_RS01010	COG1285	pathogenesis
FPS98_RS01015	COG5002	protein histidine kinase activity
FPS98_RS01020	COG0745	RESPONSE REGULATOR receiver
FPS98_RS01030	COG2309	aminopeptidase activity
FPS98_RS01040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FPS98_RS01045	COG2084	Dehydrogenase
FPS98_RS01050	COG0628	permease
FPS98_RS01070	COG1607	acyl-coa hydrolase
FPS98_RS01080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FPS98_RS01085	COG0860	N-Acetylmuramoyl-L-alanine amidase
FPS98_RS01090	COG1357	PFAM Pentapeptide repeats (8 copies)
FPS98_RS01095	COG1191	sigma factor activity
FPS98_RS01105	COG1271	oxidase subunit
FPS98_RS01110	COG1294	oxidase, subunit
FPS98_RS01115	COG4988	ABC transporter
FPS98_RS01120	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FPS98_RS01130	COG0681	Belongs to the peptidase S26 family
FPS98_RS01135	COG0456	acetyltransferase
FPS98_RS01145	COG2346	COG2346, Truncated hemoglobins
FPS98_RS01170	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FPS98_RS01180	COG0720	synthase
FPS98_RS01185	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FPS98_RS01210	COG0667	Aldo Keto reductase
FPS98_RS01215	COG1733	regulation of RNA biosynthetic process
FPS98_RS01220	COG0656	L-ascorbic acid biosynthetic process
FPS98_RS01230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FPS98_RS01275	COG0006	proline dipeptidase activity
FPS98_RS01280	COG4166	transmembrane transport
FPS98_RS01300	COG0411	ABC transporter
FPS98_RS01315	COG2204	response regulator
FPS98_RS01320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FPS98_RS01325	COG3938	Belongs to the proline racemase family
FPS98_RS01330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FPS98_RS01335	COG1012	belongs to the aldehyde dehydrogenase family
FPS98_RS01340	COG3938	Belongs to the proline racemase family
FPS98_RS01355	COG1737	Transcriptional regulator
FPS98_RS01360	COG0363	glucosamine-6-phosphate deaminase activity
FPS98_RS01365	COG3253	May function as heme-dependent peroxidase
FPS98_RS01375	COG4129	membrane
FPS98_RS01395	COG1215	transferase activity, transferring glycosyl groups
FPS98_RS01445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FPS98_RS01450	COG0765	amino acid transport
FPS98_RS01455	COG1414	Transcriptional regulator
FPS98_RS01475	COG1840	ABC-type Fe3 transport system, periplasmic component
FPS98_RS01480	COG3842	ATPase activity
FPS98_RS01500	COG0165	Argininosuccinate lyase
FPS98_RS01505	COG2971	BadF BadG BcrA BcrD
FPS98_RS01510	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FPS98_RS01515	COG0251	oxidation-reduction process
FPS98_RS01540	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FPS98_RS01540	COG2508	Transcriptional regulator
FPS98_RS01545	COG0666	response to abiotic stimulus
FPS98_RS01555	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FPS98_RS01560	COG1304	FMN binding
FPS98_RS01565	COG1953	Uracil, thiamine, allantoin
FPS98_RS01570	COG0549	Belongs to the carbamate kinase family
FPS98_RS01575	COG0590	tRNA wobble adenosine to inosine editing
FPS98_RS01585	COG4474	Belongs to the UPF0398 family
FPS98_RS01595	COG1794	racemase activity, acting on amino acids and derivatives
FPS98_RS01605	COG1840	ABC-type Fe3 transport system, periplasmic component
FPS98_RS01610	COG3842	ATPase activity
FPS98_RS01620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FPS98_RS01620	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FPS98_RS01625	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FPS98_RS01635	COG1349	DNA-binding transcription factor activity
FPS98_RS01645	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FPS98_RS01655	COG2207	Transcriptional regulator
FPS98_RS01660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPS98_RS01665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPS98_RS01675	COG2070	2-Nitropropane dioxygenase
FPS98_RS01680	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FPS98_RS01715	COG2815	serine threonine protein kinase
FPS98_RS01715	COG0515	serine threonine protein kinase
FPS98_RS01750	COG0631	protein serine/threonine phosphatase activity
FPS98_RS01825	COG3196	Protein conserved in bacteria
FPS98_RS01880	COG2091	lysine biosynthetic process via aminoadipic acid
FPS98_RS01885	COG1021	2,3-dihydroxybenzoate-AMP ligase
FPS98_RS01890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FPS98_RS01890	COG2226	methyltransferase
FPS98_RS01890	COG3433	isochorismatase activity
FPS98_RS01900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FPS98_RS01900	COG1028	Short-chain dehydrogenase reductase Sdr
FPS98_RS01900	COG3321	synthase
FPS98_RS01900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FPS98_RS01900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FPS98_RS01905	COG3433	isochorismatase activity
FPS98_RS01905	COG2226	methyltransferase
FPS98_RS01905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FPS98_RS01915	COG1515	deoxyribonuclease V activity
FPS98_RS01920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FPS98_RS01925	COG1309	transcriptional regulator
FPS98_RS01935	COG0542	response to heat
FPS98_RS01945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FPS98_RS01950	COG0697	spore germination
FPS98_RS01960	COG1176	ABC-type spermidine putrescine transport system, permease component I
FPS98_RS01965	COG1177	transmembrane transport
FPS98_RS02000	COG4549	nuclear export factor GLE1
FPS98_RS02025	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FPS98_RS02050	COG0840	transmembrane signaling receptor activity
FPS98_RS02055	COG0346	lactoylglutathione lyase activity
FPS98_RS02080	COG3279	Response regulator of the LytR AlgR family
FPS98_RS02085	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FPS98_RS02090	COG0745	RESPONSE REGULATOR receiver
FPS98_RS02090	COG2972	Histidine kinase
FPS98_RS02110	COG0531	amino acid
FPS98_RS02115	COG0697	spore germination
FPS98_RS02120	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FPS98_RS02125	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FPS98_RS02140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FPS98_RS02145	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FPS98_RS02165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FPS98_RS02170	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FPS98_RS02185	COG1473	amidohydrolase
FPS98_RS02190	COG0189	ligase activity
FPS98_RS02200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FPS98_RS02215	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FPS98_RS02220	COG1595	DNA-templated transcription, initiation
FPS98_RS02235	COG0826	peptidase U32
FPS98_RS02240	COG2205	protein histidine kinase activity
FPS98_RS02245	COG4166	transmembrane transport
FPS98_RS02260	COG3290	protein histidine kinase activity
FPS98_RS02260	COG0840	transmembrane signaling receptor activity
FPS98_RS02265	COG2357	RelA SpoT domain protein
FPS98_RS02270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FPS98_RS02275	COG1309	transcriptional regulator
FPS98_RS02280	COG2814	Major facilitator Superfamily
FPS98_RS02285	COG1363	Peptidase, m42
FPS98_RS02310	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FPS98_RS02310	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FPS98_RS02325	COG1012	belongs to the aldehyde dehydrogenase family
FPS98_RS02330	COG0840	transmembrane signaling receptor activity
FPS98_RS02350	COG1959	2 iron, 2 sulfur cluster binding
FPS98_RS02355	COG3118	belongs to the thioredoxin family
FPS98_RS02360	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FPS98_RS02375	COG3275	phosphorelay sensor kinase activity
FPS98_RS02390	COG1966	Carbon starvation protein
FPS98_RS02400	COG0483	inositol monophosphate 1-phosphatase activity
FPS98_RS02405	COG3387	PFAM Glycoside hydrolase 15-related
FPS98_RS02420	COG0583	DNA-binding transcription factor activity
FPS98_RS02435	COG0778	Nitroreductase
FPS98_RS02470	COG1126	abc transporter atp-binding protein
FPS98_RS02475	COG0765	amino acid transport
FPS98_RS02480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FPS98_RS02485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FPS98_RS02505	COG0488	(ABC) transporter
FPS98_RS02540	COG0840	transmembrane signaling receptor activity
FPS98_RS02550	COG0446	pyridine nucleotide-disulphide oxidoreductase
FPS98_RS02550	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FPS98_RS02560	COG1349	DNA-binding transcription factor activity
FPS98_RS02565	COG0531	amino acid
FPS98_RS02570	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FPS98_RS02585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FPS98_RS02605	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FPS98_RS02620	COG1131	(ABC) transporter
FPS98_RS02635	COG0667	Aldo Keto reductase
FPS98_RS02660	COG2851	Citrate transporter
FPS98_RS02665	COG3290	protein histidine kinase activity
FPS98_RS02670	COG4565	transcriptional regulatory protein
FPS98_RS02680	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FPS98_RS02690	COG0791	NLP P60 protein
FPS98_RS02705	COG0129	dihydroxy-acid dehydratase activity
FPS98_RS02720	COG0483	inositol monophosphate 1-phosphatase activity
FPS98_RS02745	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FPS98_RS02750	COG0583	DNA-binding transcription factor activity
FPS98_RS02755	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FPS98_RS02765	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FPS98_RS02775	COG1587	Uroporphyrinogen-III synthase
FPS98_RS02775	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FPS98_RS02780	COG0175	sulfate reduction
FPS98_RS02785	COG2046	Belongs to the sulfate adenylyltransferase family
FPS98_RS02790	COG0529	Catalyzes the synthesis of activated sulfate
FPS98_RS02800	COG1674	ftsk spoiiie
FPS98_RS02810	COG5434	Belongs to the glycosyl hydrolase 28 family
FPS98_RS02830	COG1316	TRANSCRIPTIONal
FPS98_RS02840	COG0489	protein tyrosine kinase activity
FPS98_RS02855	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FPS98_RS02875	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FPS98_RS02885	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FPS98_RS02895	COG0151	Belongs to the GarS family
FPS98_RS02900	COG0500	methyltransferase
FPS98_RS02925	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FPS98_RS02930	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FPS98_RS02935	COG3829	transcription factor binding
FPS98_RS02945	COG2207	Transcriptional regulator
FPS98_RS02950	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FPS98_RS02955	COG1228	amidohydrolase
FPS98_RS02985	COG0464	growth
FPS98_RS03070	COG0656	L-ascorbic acid biosynthetic process
FPS98_RS03075	COG1414	Transcriptional regulator
FPS98_RS03090	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FPS98_RS03105	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FPS98_RS03110	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FPS98_RS03115	COG1132	(ABC) transporter
FPS98_RS03120	COG0745	RESPONSE REGULATOR receiver
FPS98_RS03125	COG5002	protein histidine kinase activity
FPS98_RS03130	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FPS98_RS03135	COG0314	molybdopterin synthase activity
FPS98_RS03150	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FPS98_RS03155	COG0315	cyclic pyranopterin monophosphate synthase activity
FPS98_RS03160	COG2814	Major facilitator Superfamily
FPS98_RS03165	COG0436	Aminotransferase
FPS98_RS03175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FPS98_RS03180	COG2267	carboxylic ester hydrolase activity
FPS98_RS03200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FPS98_RS03210	COG1733	regulation of RNA biosynthetic process
FPS98_RS03225	COG1695	Transcriptional regulator
FPS98_RS03250	COG3118	belongs to the thioredoxin family
FPS98_RS03260	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FPS98_RS03260	COG1605	Chorismate mutase
FPS98_RS03275	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FPS98_RS03280	COG0123	including yeast histone deacetylase and acetoin utilization protein
FPS98_RS03285	COG0517	IMP dehydrogenase activity
FPS98_RS03290	COG0454	-acetyltransferase
FPS98_RS03300	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FPS98_RS03315	COG2203	Gaf domain
FPS98_RS03315	COG2199	diguanylate cyclase activity
FPS98_RS03320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPS98_RS03340	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FPS98_RS03350	COG2081	HI0933 family
FPS98_RS03360	COG1363	Peptidase, m42
FPS98_RS03390	COG4326	sporulation control protein
FPS98_RS03395	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FPS98_RS03410	COG0747	negative chemotaxis
FPS98_RS03420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPS98_RS03425	COG0444	Belongs to the ABC transporter superfamily
FPS98_RS03430	COG4608	Belongs to the ABC transporter superfamily
FPS98_RS03435	COG4948	Mandelate Racemase Muconate Lactonizing
FPS98_RS03465	COG4221	oxidoreductase activity
FPS98_RS03475	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
FPS98_RS03490	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FPS98_RS03495	COG1104	cysteine desulfurase activity
FPS98_RS03500	COG0301	tRNA thio-modification
FPS98_RS03505	COG0179	Fumarylacetoacetate (FAA) hydrolase
FPS98_RS03605	COG4191	Histidine kinase
FPS98_RS03610	COG0861	Integral membrane protein TerC family
FPS98_RS03615	COG0726	polysaccharide deacetylase
FPS98_RS03620	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FPS98_RS03635	COG2323	membrane
FPS98_RS03645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FPS98_RS03660	COG3584	3D domain protein
FPS98_RS03660	COG1388	LysM domain
FPS98_RS03670	COG3874	Sporulation protein YtfJ
FPS98_RS03680	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FPS98_RS03695	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FPS98_RS03705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPS98_RS03715	COG0564	pseudouridine synthase activity
FPS98_RS03720	COG0179	Fumarylacetoacetate (FAA) hydrolase
FPS98_RS03725	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FPS98_RS03730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FPS98_RS03745	COG1309	transcriptional regulator
FPS98_RS03750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FPS98_RS03755	COG0024	Methionine aminopeptidase
FPS98_RS03760	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FPS98_RS03780	COG0586	Pfam SNARE associated Golgi protein
FPS98_RS03790	COG3481	metal-dependent phosphohydrolase, HD sub domain
FPS98_RS03810	COG0653	protein targeting
FPS98_RS03815	COG2223	nitrite transmembrane transporter activity
FPS98_RS03825	COG1316	TRANSCRIPTIONal
FPS98_RS03840	COG1902	pentaerythritol trinitrate reductase activity
FPS98_RS03840	COG0446	pyridine nucleotide-disulphide oxidoreductase
FPS98_RS03850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPS98_RS03855	COG2211	Major facilitator Superfamily
FPS98_RS03870	COG0745	RESPONSE REGULATOR receiver
FPS98_RS03875	COG2205	protein histidine kinase activity
FPS98_RS03880	COG1136	(ABC) transporter
FPS98_RS03900	COG1131	(ABC) transporter
FPS98_RS03905	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FPS98_RS03935	COG1595	DNA-templated transcription, initiation
FPS98_RS03945	COG1253	flavin adenine dinucleotide binding
FPS98_RS03960	COG4120	Belongs to the binding-protein-dependent transport system permease family
FPS98_RS03965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FPS98_RS03965	COG1116	anion transmembrane transporter activity
FPS98_RS03970	COG0477	Major facilitator Superfamily
FPS98_RS03970	COG2814	Major facilitator Superfamily
FPS98_RS03975	COG4533	DNA binding
FPS98_RS03985	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FPS98_RS04000	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FPS98_RS04010	COG0835	chemotaxis
FPS98_RS04020	COG0861	Integral membrane protein TerC family
FPS98_RS04045	COG0210	DNA helicase
FPS98_RS04050	COG1253	flavin adenine dinucleotide binding
FPS98_RS04060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPS98_RS04070	COG0613	PHP domain protein
FPS98_RS04090	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FPS98_RS04100	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FPS98_RS04195	COG0250	Participates in transcription elongation, termination and antitermination
FPS98_RS04205	COG2070	2-Nitropropane dioxygenase
FPS98_RS04205	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FPS98_RS04210	COG2267	carboxylic ester hydrolase activity
FPS98_RS04220	COG4221	oxidoreductase activity
FPS98_RS04220	COG3321	synthase
FPS98_RS04220	COG1028	Short-chain dehydrogenase reductase Sdr
FPS98_RS04220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FPS98_RS04225	COG4221	oxidoreductase activity
FPS98_RS04225	COG3321	synthase
FPS98_RS04225	COG1028	Short-chain dehydrogenase reductase Sdr
FPS98_RS04225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FPS98_RS04230	COG4221	oxidoreductase activity
FPS98_RS04230	COG3321	synthase
FPS98_RS04230	COG1028	Short-chain dehydrogenase reductase Sdr
FPS98_RS04230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FPS98_RS04235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FPS98_RS04235	COG1028	Short-chain dehydrogenase reductase Sdr
FPS98_RS04235	COG3321	synthase
FPS98_RS04235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FPS98_RS04235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FPS98_RS04240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FPS98_RS04240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FPS98_RS04240	COG1028	Short-chain dehydrogenase reductase Sdr
FPS98_RS04240	COG3321	synthase
FPS98_RS04240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FPS98_RS04250	COG0367	asparagine synthase
FPS98_RS04270	COG0583	DNA-binding transcription factor activity
FPS98_RS04280	COG0786	glutamate:sodium symporter activity
FPS98_RS04305	COG1595	DNA-templated transcription, initiation
FPS98_RS04315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FPS98_RS04320	COG1231	oxidoreductase activity
FPS98_RS04340	COG1193	negative regulation of DNA recombination
FPS98_RS04345	COG2814	Major facilitator Superfamily
FPS98_RS04350	COG0316	Belongs to the HesB IscA family
FPS98_RS04390	COG0778	Nitroreductase
FPS98_RS04395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPS98_RS04400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPS98_RS04405	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FPS98_RS04410	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FPS98_RS04410	COG0456	acetyltransferase
FPS98_RS04425	COG1227	inorganic diphosphatase activity
FPS98_RS04430	COG0789	Transcriptional regulator
FPS98_RS04440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPS98_RS04450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPS98_RS04455	COG1120	ATPase activity
FPS98_RS04460	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
FPS98_RS04475	COG4991	sh3 domain protein
FPS98_RS04475	COG0860	N-Acetylmuramoyl-L-alanine amidase
FPS98_RS04475	COG3103	Sh3 type 3 domain protein
FPS98_RS04500	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FPS98_RS04550	COG2962	Rard protein
FPS98_RS04555	COG0351	phosphomethylpyrimidine kinase
FPS98_RS04560	COG0577	efflux transmembrane transporter activity
FPS98_RS04560	COG1136	(ABC) transporter
FPS98_RS04565	COG0577	efflux transmembrane transporter activity
FPS98_RS04580	COG4106	trans-aconitate 2-methyltransferase activity
FPS98_RS04595	COG2217	Heavy metal translocating P-type atpase
FPS98_RS04605	COG0716	FMN binding
FPS98_RS04610	COG2171	N-acyltransferase activity
FPS98_RS04615	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FPS98_RS04620	COG1473	amidohydrolase
FPS98_RS04635	COG1705	Flagellar rod assembly protein muramidase FlgJ
FPS98_RS04655	COG2267	carboxylic ester hydrolase activity
FPS98_RS04670	COG0167	dihydroorotate dehydrogenase activity
FPS98_RS04675	COG1982	Orn Lys Arg decarboxylase major
FPS98_RS04685	COG4493	Belongs to the UPF0637 family
FPS98_RS04715	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FPS98_RS04725	COG1217	gtp-binding protein TYPA
FPS98_RS04730	COG0386	Belongs to the glutathione peroxidase family
FPS98_RS04760	COG0626	cystathionine gamma-synthase activity
FPS98_RS04765	COG0626	cystathionine gamma-synthase activity
FPS98_RS04775	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FPS98_RS04800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPS98_RS04805	COG2843	Capsule synthesis protein
FPS98_RS04835	COG1393	Belongs to the ArsC family
FPS98_RS04840	COG1024	Enoyl-CoA hydratase
FPS98_RS04850	COG0454	-acetyltransferase
FPS98_RS04855	COG0439	Biotin carboxylase
FPS98_RS04860	COG0511	ligase activity, forming carbon-carbon bonds
FPS98_RS04865	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FPS98_RS04870	COG1024	Enoyl-CoA hydratase
FPS98_RS04875	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FPS98_RS04880	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FPS98_RS04895	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
FPS98_RS04900	COG3266	domain, Protein
FPS98_RS04900	COG2911	Protein conserved in bacteria
FPS98_RS04900	COG1361	Conserved repeat domain
FPS98_RS04910	COG0583	DNA-binding transcription factor activity
FPS98_RS04915	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FPS98_RS04920	COG2001	Belongs to the MraZ family
FPS98_RS04925	COG0275	rRNA processing
FPS98_RS04935	COG0768	penicillin binding
FPS98_RS04940	COG0768	penicillin binding
FPS98_RS04950	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FPS98_RS04955	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FPS98_RS04960	COG0772	Belongs to the SEDS family
FPS98_RS04965	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FPS98_RS04970	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FPS98_RS04975	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FPS98_RS04980	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FPS98_RS04995	COG3856	small basic protein
FPS98_RS05000	COG0849	cell division
FPS98_RS05005	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FPS98_RS05015	COG1191	sigma factor activity
FPS98_RS05020	COG1191	sigma factor activity
FPS98_RS05025	COG1873	PFAM PRC-barrel domain
FPS98_RS05030	COG1496	oxidoreductase activity
FPS98_RS05035	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FPS98_RS05040	COG1799	cell septum assembly
FPS98_RS05045	COG0762	integral membrane protein
FPS98_RS05050	COG2302	S4 RNA-binding domain
FPS98_RS05055	COG3599	regulation of cell shape
FPS98_RS05060	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FPS98_RS05065	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FPS98_RS05070	COG4948	Mandelate Racemase Muconate Lactonizing
FPS98_RS05075	COG2814	Major facilitator Superfamily
FPS98_RS05080	COG0494	nUDIX hydrolase
FPS98_RS05085	COG0492	ferredoxin-NADP+ reductase activity
FPS98_RS05090	COG1316	TRANSCRIPTIONal
FPS98_RS05100	COG3848	Pyruvate phosphate dikinase
FPS98_RS05100	COG0574	Belongs to the PEP-utilizing enzyme family
FPS98_RS05140	COG1657	PFAM Prenyltransferase squalene oxidase
FPS98_RS05155	COG1842	Phage shock protein A
FPS98_RS05190	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FPS98_RS05200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FPS98_RS05205	COG2112	serine threonine protein kinase
FPS98_RS05210	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FPS98_RS05215	COG0564	pseudouridine synthase activity
FPS98_RS05230	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FPS98_RS05240	COG0540	Belongs to the ATCase OTCase family
FPS98_RS05245	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FPS98_RS05255	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FPS98_RS05260	COG0284	orotidine-5'-phosphate decarboxylase activity
FPS98_RS05265	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FPS98_RS05275	COG0640	Transcriptional regulator
FPS98_RS05305	COG1222	aaa ATPase
FPS98_RS05310	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FPS98_RS05315	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FPS98_RS05320	COG0673	inositol 2-dehydrogenase activity
FPS98_RS05325	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FPS98_RS05330	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FPS98_RS05335	COG0460	homoserine dehydrogenase
FPS98_RS05340	COG2843	Capsule synthesis protein
FPS98_RS05350	COG4846	Membrane protein involved in cytochrome C biogenesis
FPS98_RS05370	COG1547	Domain of unknown function (DUF309)
FPS98_RS05400	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FPS98_RS05405	COG1024	Enoyl-CoA hydratase
FPS98_RS05430	COG1293	RNA-binding protein homologous to eukaryotic snRNP
FPS98_RS05435	COG1561	YicC-like family, N-terminal region
FPS98_RS05440	COG2052	Domain of unknown function (DUF370)
FPS98_RS05445	COG0194	GDP metabolic process
FPS98_RS05450	COG1758	RNA polymerase activity
FPS98_RS05455	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FPS98_RS05460	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FPS98_RS05465	COG0242	peptide deformylase activity
FPS98_RS05470	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FPS98_RS05475	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FPS98_RS05475	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FPS98_RS05480	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FPS98_RS05485	COG0631	protein serine/threonine phosphatase activity
FPS98_RS05490	COG0515	serine threonine protein kinase
FPS98_RS05490	COG2815	serine threonine protein kinase
FPS98_RS05495	COG1162	GTPase activity
FPS98_RS05500	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FPS98_RS05510	COG1714	RDD family
FPS98_RS05520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FPS98_RS05525	COG0765	amino acid transport
FPS98_RS05530	COG1126	abc transporter atp-binding protein
FPS98_RS05535	COG3859	Proton-coupled thiamine transporter YuaJ
FPS98_RS05545	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FPS98_RS05550	COG1302	Protein conserved in bacteria
FPS98_RS05555	COG1461	Dihydroxyacetone kinase
FPS98_RS05560	COG1307	EDD domain protein, DegV family
FPS98_RS05570	COG1760	l-serine dehydratase
FPS98_RS05575	COG1760	l-serine dehydratase
FPS98_RS05580	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FPS98_RS05600	COG3708	Transcriptional regulator
FPS98_RS05600	COG2207	Transcriptional regulator
FPS98_RS05605	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FPS98_RS05630	COG1132	(ABC) transporter
FPS98_RS05635	COG0477	Major facilitator Superfamily
FPS98_RS05640	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FPS98_RS05655	COG0583	DNA-binding transcription factor activity
FPS98_RS05660	COG5522	Integral membrane protein (intg_mem_TP0381)
FPS98_RS05670	COG1027	Aspartate ammonia-lyase
FPS98_RS05685	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FPS98_RS05690	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FPS98_RS05695	COG0438	transferase activity, transferring glycosyl groups
FPS98_RS05720	COG0714	Associated with various cellular activities
FPS98_RS05745	COG4632	Exopolysaccharide biosynthesis protein
FPS98_RS05745	COG5434	Belongs to the glycosyl hydrolase 28 family
FPS98_RS05750	COG0405	Gamma-glutamyltransferase
FPS98_RS05760	COG1876	peptidase activity
FPS98_RS05765	COG0681	Belongs to the peptidase S26 family
FPS98_RS05770	COG1846	Transcriptional regulator
FPS98_RS05795	COG1755	Isoprenylcysteine carboxyl methyltransferase
FPS98_RS05800	COG3424	synthase
FPS98_RS05805	COG3706	GGDEF domain
FPS98_RS05815	COG0306	phosphate transporter
FPS98_RS05825	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FPS98_RS05830	COG1793	dna ligase
FPS98_RS05830	COG3285	dna ligase
FPS98_RS05835	COG0697	spore germination
FPS98_RS05855	COG1733	regulation of RNA biosynthetic process
FPS98_RS05860	COG0778	Nitroreductase
FPS98_RS05865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FPS98_RS05880	COG1793	dna ligase
FPS98_RS05890	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FPS98_RS05895	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FPS98_RS05900	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FPS98_RS05910	COG0742	ribosomal rna small subunit methyltransferase
FPS98_RS05915	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FPS98_RS05920	COG3314	Sporulation integral membrane protein YlbJ
FPS98_RS05925	COG1752	Esterase of the alpha-beta hydrolase superfamily
FPS98_RS05930	COG3480	Lon protease (S16) C-terminal proteolytic domain
FPS98_RS05940	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FPS98_RS05945	COG1349	DNA-binding transcription factor activity
FPS98_RS05960	COG4555	ABC transporter
FPS98_RS05965	COG1349	DNA-binding transcription factor activity
FPS98_RS05965	COG2050	protein possibly involved in aromatic compounds catabolism
FPS98_RS05970	COG0416	fatty acid biosynthetic process
FPS98_RS05975	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FPS98_RS05980	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FPS98_RS05985	COG1028	Short-chain dehydrogenase reductase Sdr
FPS98_RS05990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FPS98_RS05995	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FPS98_RS06000	COG0571	ribonuclease III activity
FPS98_RS06005	COG1196	nuclear chromosome segregation
FPS98_RS06010	COG0552	protein localization to endoplasmic reticulum
FPS98_RS06015	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FPS98_RS06020	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FPS98_RS06025	COG0228	four-way junction DNA binding
FPS98_RS06030	COG1837	Belongs to the UPF0109 family
FPS98_RS06040	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FPS98_RS06045	COG0336	Belongs to the RNA methyltransferase TrmD family
FPS98_RS06050	COG0335	large ribosomal subunit rRNA binding
FPS98_RS06055	COG0681	Belongs to the peptidase S26 family
FPS98_RS06065	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FPS98_RS06075	COG2257	FlhB HrpN YscU SpaS Family
FPS98_RS06080	COG0792	nuclease activity
FPS98_RS06090	COG3541	Predicted nucleotidyltransferase
FPS98_RS06110	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FPS98_RS06175	COG0606	chelatase, subunit chli
FPS98_RS06190	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FPS98_RS06200	COG5001	Diguanylate cyclase
FPS98_RS06205	COG0393	Putative heavy-metal-binding
FPS98_RS06225	COG0045	succinate-CoA ligase (ADP-forming) activity
FPS98_RS06230	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FPS98_RS06235	COG0758	DNA mediated transformation
FPS98_RS06240	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FPS98_RS06245	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FPS98_RS06250	COG4974	Belongs to the 'phage' integrase family
FPS98_RS06255	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FPS98_RS06260	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FPS98_RS06265	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FPS98_RS06270	COG1815	bacterial-type flagellum-dependent cell motility
FPS98_RS06275	COG1558	bacterial-type flagellum-dependent cell motility
FPS98_RS06280	COG1677	Flagellar hook-basal body complex protein FliE
FPS98_RS06285	COG1766	The M ring may be actively involved in energy transduction
FPS98_RS06290	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FPS98_RS06300	COG1157	protein secretion by the type III secretion system
FPS98_RS06325	COG4786	Flagellar basal body rod
FPS98_RS06340	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FPS98_RS06345	COG1776	CheC inhibitor of MCP methylation
FPS98_RS06345	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FPS98_RS06350	COG2201	protein-glutamate methylesterase activity
FPS98_RS06355	COG3190	flagellar
FPS98_RS06360	COG1338	Plays a role in the flagellum-specific transport system
FPS98_RS06365	COG1987	bacterial-type flagellum assembly
FPS98_RS06370	COG1684	flagellar biosynthetic protein fliR
FPS98_RS06375	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FPS98_RS06380	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FPS98_RS06385	COG1419	protein localization to endoplasmic reticulum
FPS98_RS06390	COG0455	bacterial-type flagellum organization
FPS98_RS06395	COG2201	protein-glutamate methylesterase activity
FPS98_RS06400	COG2198	Histidine kinase
FPS98_RS06400	COG0643	Histidine kinase
FPS98_RS06405	COG0835	chemotaxis
FPS98_RS06410	COG1776	CheC inhibitor of MCP methylation
FPS98_RS06415	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FPS98_RS06425	COG1191	sigma factor activity
FPS98_RS06450	COG0052	Belongs to the universal ribosomal protein uS2 family
FPS98_RS06455	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FPS98_RS06460	COG0528	UMP kinase activity
FPS98_RS06465	COG0233	cytoplasmic translational termination
FPS98_RS06475	COG4589	Belongs to the CDS family
FPS98_RS06480	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FPS98_RS06485	COG0750	zinc metalloprotease
FPS98_RS06490	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FPS98_RS06495	COG0442	prolyl-tRNA aminoacylation
FPS98_RS06500	COG2176	DNA-directed DNA polymerase activity
FPS98_RS06505	COG0779	Required for maturation of 30S ribosomal subunits
FPS98_RS06510	COG0195	Participates in both transcription termination and antitermination
FPS98_RS06520	COG1358	cellular component organization or biogenesis
FPS98_RS06525	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FPS98_RS06525	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FPS98_RS06535	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FPS98_RS06540	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FPS98_RS06545	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FPS98_RS06550	COG0196	riboflavin kinase activity
FPS98_RS06555	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FPS98_RS06560	COG1185	polyribonucleotide nucleotidyltransferase activity
FPS98_RS06565	COG0726	polysaccharide deacetylase
FPS98_RS06570	COG0612	Peptidase, M16
FPS98_RS06580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FPS98_RS06585	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FPS98_RS06590	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FPS98_RS06595	COG0527	aspartate kinase activity
FPS98_RS06600	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FPS98_RS06605	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FPS98_RS06610	COG0740	serine-type endopeptidase activity
FPS98_RS06620	COG4980	gas vesicle protein
FPS98_RS06620	COG1674	ftsk spoiiie
FPS98_RS06625	COG2188	Transcriptional regulator
FPS98_RS06630	COG1744	ABC transporter substrate-binding protein PnrA-like
FPS98_RS06635	COG3845	ABC transporter
FPS98_RS06640	COG4603	Belongs to the binding-protein-dependent transport system permease family
FPS98_RS06645	COG1079	Belongs to the binding-protein-dependent transport system permease family
FPS98_RS06655	COG0612	Peptidase, M16
FPS98_RS06660	COG0612	Peptidase, M16
FPS98_RS06665	COG0300	oxidoreductase activity
FPS98_RS06680	COG1426	Protein conserved in bacteria
FPS98_RS06685	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FPS98_RS06690	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FPS98_RS06695	COG1546	Belongs to the CinA family
FPS98_RS06695	COG1058	Belongs to the CinA family
FPS98_RS06700	COG0513	Belongs to the DEAD box helicase family
FPS98_RS06705	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FPS98_RS06710	COG2137	regulation of response to DNA damage stimulus
FPS98_RS06720	COG1692	metallophosphoesterase
FPS98_RS06725	COG2359	stage V sporulation protein S
FPS98_RS06735	COG0674	pyruvate-flavodoxin oxidoreductase activity
FPS98_RS06735	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FPS98_RS06740	COG1013	pyruvate-flavodoxin oxidoreductase activity
FPS98_RS06745	COG3949	Membrane
FPS98_RS06750	COG1234	tRNA 3'-trailer cleavage
FPS98_RS06755	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FPS98_RS06765	COG0517	IMP dehydrogenase activity
FPS98_RS06775	COG0095	Lipoate-protein ligase
FPS98_RS06780	COG3693	PFAM glycoside hydrolase, family 10
FPS98_RS06790	COG4550	Control of competence regulator ComK, YlbF/YmcA
FPS98_RS06805	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FPS98_RS06810	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FPS98_RS06820	COG2136	Putative SAM-dependent methyltransferase
FPS98_RS06820	COG2521	methyltransferase
FPS98_RS06825	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FPS98_RS06830	COG1923	regulation of RNA biosynthetic process
FPS98_RS06835	COG2764	glyoxalase bleomycin resistance protein dioxygenase
FPS98_RS06840	COG2814	Major facilitator Superfamily
FPS98_RS06845	COG1846	Transcriptional regulator
FPS98_RS06850	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FPS98_RS06860	COG0464	growth
FPS98_RS06895	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FPS98_RS06900	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FPS98_RS06905	COG0789	Transcriptional regulator
FPS98_RS06910	COG0174	glutamine synthetase
FPS98_RS06915	COG0582	viral genome integration into host DNA
FPS98_RS06995	COG0640	Transcriptional regulator
FPS98_RS07000	COG0346	lactoylglutathione lyase activity
FPS98_RS07005	COG0798	PFAM Bile acid sodium symporter
FPS98_RS07010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FPS98_RS07025	COG3209	COG3209 Rhs family protein
FPS98_RS07055	COG2135	peptidase activity
FPS98_RS07060	COG3209	COG3209 Rhs family protein
FPS98_RS07065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FPS98_RS07115	COG0640	Transcriptional regulator
FPS98_RS07130	COG5566	PFAM Mor transcription activator
FPS98_RS07145	COG3858	chitin binding
FPS98_RS07160	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FPS98_RS07165	COG1388	LysM domain
FPS98_RS07165	COG3942	CHAP domain
FPS98_RS07170	COG4224	UPF0291 protein
FPS98_RS07175	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FPS98_RS07180	COG3973	AAA domain
FPS98_RS07195	COG4166	transmembrane transport
FPS98_RS07215	COG0022	dehydrogenase e1 component
FPS98_RS07220	COG0508	dehydrogenase complex catalyzes the overall conversion of
FPS98_RS07250	COG0488	(ABC) transporter
FPS98_RS07280	COG4848	Belongs to the UPF0354 family
FPS98_RS07305	COG2707	UPF0756 membrane protein
FPS98_RS07325	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FPS98_RS07335	COG1595	DNA-templated transcription, initiation
FPS98_RS07350	COG1131	(ABC) transporter
FPS98_RS07375	COG0187	DNA topoisomerase II activity
FPS98_RS07380	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FPS98_RS07390	COG0778	Nitroreductase
FPS98_RS07395	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FPS98_RS07415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FPS98_RS07430	COG1846	Transcriptional regulator
FPS98_RS07435	COG2814	Major facilitator Superfamily
FPS98_RS07440	COG0464	growth
FPS98_RS07450	COG3835	regulator
FPS98_RS07455	COG1012	belongs to the aldehyde dehydrogenase family
FPS98_RS07460	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FPS98_RS07480	COG1694	Mazg nucleotide pyrophosphohydrolase
FPS98_RS07485	COG1611	Belongs to the LOG family
FPS98_RS07510	COG0493	'glutamate synthase
FPS98_RS07515	COG0167	dihydroorotate dehydrogenase activity
FPS98_RS07515	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FPS98_RS07535	COG0840	transmembrane signaling receptor activity
FPS98_RS07540	COG1953	Uracil, thiamine, allantoin
FPS98_RS07545	COG3290	protein histidine kinase activity
FPS98_RS07550	COG4565	transcriptional regulatory protein
FPS98_RS07585	COG0352	thiamine-phosphate diphosphorylase activity
FPS98_RS07605	COG3852	Histidine kinase
FPS98_RS07615	COG2197	response regulator
FPS98_RS07620	COG4585	Histidine kinase
FPS98_RS07645	COG0785	Cytochrome C biogenesis protein
FPS98_RS07650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FPS98_RS07660	COG3093	addiction module antidote protein HigA
FPS98_RS07750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FPS98_RS07760	COG1475	DNA binding
FPS98_RS07785	COG1309	transcriptional regulator
FPS98_RS07790	COG2814	Major facilitator Superfamily
FPS98_RS07795	COG4989	oxidoreductase activity
FPS98_RS07840	COG1011	Hydrolase
FPS98_RS07845	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FPS98_RS07855	COG3964	amidohydrolase
FPS98_RS07895	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FPS98_RS07920	COG0745	RESPONSE REGULATOR receiver
FPS98_RS07925	COG2205	protein histidine kinase activity
FPS98_RS07940	COG1136	(ABC) transporter
FPS98_RS07945	COG0577	efflux transmembrane transporter activity
FPS98_RS07965	COG4122	O-methyltransferase activity
FPS98_RS07980	COG0385	Bile acid
FPS98_RS07995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FPS98_RS08010	COG0584	glycerophosphoryl diester phosphodiesterase
FPS98_RS08035	COG0482	sulfurtransferase activity
FPS98_RS08050	COG2819	hydrolase of the alpha beta superfamily
FPS98_RS08055	COG1780	Probably involved in ribonucleotide reductase function
FPS98_RS08060	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FPS98_RS08065	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FPS98_RS08070	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FPS98_RS08075	COG1607	acyl-coa hydrolase
FPS98_RS08085	COG1136	(ABC) transporter
FPS98_RS08090	COG0577	efflux transmembrane transporter activity
FPS98_RS08100	COG0745	RESPONSE REGULATOR receiver
FPS98_RS08105	COG2205	protein histidine kinase activity
FPS98_RS08115	COG2801	Transposase and inactivated derivatives
FPS98_RS08125	COG2843	Capsule synthesis protein
FPS98_RS08135	COG0318	PFAM AMP-dependent synthetase and ligase
FPS98_RS08140	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FPS98_RS08140	COG0456	acetyltransferase
FPS98_RS08180	COG1131	(ABC) transporter
FPS98_RS08240	COG1595	DNA-templated transcription, initiation
FPS98_RS08270	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FPS98_RS08275	COG0583	DNA-binding transcription factor activity
FPS98_RS08285	COG1733	regulation of RNA biosynthetic process
FPS98_RS08325	COG2084	Dehydrogenase
FPS98_RS08330	COG0515	serine threonine protein kinase
FPS98_RS08335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FPS98_RS08340	COG3858	chitin binding
FPS98_RS08340	COG1388	LysM domain
FPS98_RS08350	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FPS98_RS08360	COG2104	thiamine diphosphate biosynthetic process
FPS98_RS08365	COG2022	thiamine diphosphate biosynthetic process
FPS98_RS08370	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FPS98_RS08375	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FPS98_RS08380	COG1116	anion transmembrane transporter activity
FPS98_RS08385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FPS98_RS08390	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FPS98_RS08395	COG2205	protein histidine kinase activity
FPS98_RS08400	COG0745	RESPONSE REGULATOR receiver
FPS98_RS08425	COG2027	D-alanyl-D-alanine carboxypeptidase
FPS98_RS08430	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FPS98_RS08435	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FPS98_RS08445	COG1114	Component of the transport system for branched-chain amino acids
FPS98_RS08450	COG2311	Membrane
FPS98_RS08455	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FPS98_RS08455	COG0069	glutamate synthase activity
FPS98_RS08460	COG3361	conserved protein (COG2071)
FPS98_RS08470	COG0697	spore germination
FPS98_RS08480	COG0242	peptide deformylase activity
FPS98_RS08490	COG2340	Cysteine-rich secretory protein family
FPS98_RS08500	COG1278	Cold shock
FPS98_RS08515	COG0753	catalase activity
FPS98_RS08540	COG0840	transmembrane signaling receptor activity
FPS98_RS08570	COG2249	NAD(P)H dehydrogenase (quinone) activity
FPS98_RS08580	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FPS98_RS08590	COG0697	spore germination
FPS98_RS08595	COG0531	amino acid
FPS98_RS08625	COG0789	Transcriptional regulator
FPS98_RS08665	COG3949	Membrane
FPS98_RS08670	COG3069	C4-dicarboxylate transmembrane transporter activity
FPS98_RS08675	COG0714	Associated with various cellular activities
FPS98_RS08710	COG2357	RelA SpoT domain protein
FPS98_RS08715	COG1686	Belongs to the peptidase S11 family
FPS98_RS08730	COG0813	purine-nucleoside phosphorylase activity
FPS98_RS08755	COG0860	N-Acetylmuramoyl-L-alanine amidase
FPS98_RS08780	COG0384	phenazine biosynthesis protein PhzF
FPS98_RS08790	COG1595	DNA-templated transcription, initiation
FPS98_RS08805	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FPS98_RS08810	COG0477	Major facilitator Superfamily
FPS98_RS08820	COG0789	Transcriptional regulator
FPS98_RS08820	COG4978	Transcriptional regulator
FPS98_RS08835	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FPS98_RS08840	COG4569	acetaldehyde dehydrogenase (acetylating) activity
FPS98_RS08845	COG3971	2-oxopent-4-enoate hydratase activity
FPS98_RS08870	COG2368	4-hydroxyphenylacetate
FPS98_RS08910	COG5002	protein histidine kinase activity
FPS98_RS08915	COG0745	RESPONSE REGULATOR receiver
FPS98_RS08935	COG0393	Putative heavy-metal-binding
FPS98_RS08955	COG2205	protein histidine kinase activity
FPS98_RS08960	COG5646	InterPro IPR014922
FPS98_RS08970	COG0640	Transcriptional regulator
FPS98_RS08975	COG5002	protein histidine kinase activity
FPS98_RS08975	COG3850	Histidine kinase
FPS98_RS08980	COG0745	RESPONSE REGULATOR receiver
FPS98_RS08990	COG1136	(ABC) transporter
FPS98_RS08990	COG0577	efflux transmembrane transporter activity
FPS98_RS09000	COG5002	protein histidine kinase activity
FPS98_RS09000	COG3850	Histidine kinase
FPS98_RS09005	COG0745	RESPONSE REGULATOR receiver
FPS98_RS09015	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FPS98_RS09040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FPS98_RS09045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FPS98_RS09050	COG2195	Cleaves the N-terminal amino acid of tripeptides
FPS98_RS09065	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FPS98_RS09070	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FPS98_RS09075	COG4608	Belongs to the ABC transporter superfamily
FPS98_RS09080	COG0444	Belongs to the ABC transporter superfamily
FPS98_RS09085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPS98_RS09090	COG0601	transmembrane transport
FPS98_RS09095	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FPS98_RS09100	COG0747	negative chemotaxis
FPS98_RS09105	COG1363	Peptidase, m42
FPS98_RS09125	COG1309	transcriptional regulator
FPS98_RS09135	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FPS98_RS09135	COG2755	lipolytic protein G-D-S-L family
FPS98_RS09140	COG2755	lipolytic protein G-D-S-L family
FPS98_RS09140	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FPS98_RS09155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FPS98_RS09160	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FPS98_RS09165	COG0747	negative chemotaxis
FPS98_RS09180	COG1396	sequence-specific DNA binding
FPS98_RS09190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FPS98_RS09200	COG0006	proline dipeptidase activity
FPS98_RS09205	COG4166	transmembrane transport
FPS98_RS09210	COG4608	Belongs to the ABC transporter superfamily
FPS98_RS09215	COG0444	Belongs to the ABC transporter superfamily
FPS98_RS09220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPS98_RS09225	COG0601	transmembrane transport
FPS98_RS09230	COG0730	response to heat
FPS98_RS09235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPS98_RS09250	COG2197	response regulator
FPS98_RS09255	COG4585	Histidine kinase
FPS98_RS09260	COG2814	Major facilitator Superfamily
FPS98_RS09270	COG4191	Histidine kinase
FPS98_RS09275	COG0662	Cupin 2, conserved barrel domain protein
FPS98_RS09285	COG2068	MobA-Related Protein
FPS98_RS09290	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FPS98_RS09295	COG2080	2 iron, 2 sulfur cluster binding
FPS98_RS09310	COG2258	MOSC domain
FPS98_RS09360	COG5002	protein histidine kinase activity
FPS98_RS09365	COG0745	RESPONSE REGULATOR receiver
FPS98_RS09370	COG0791	NLP P60 protein
FPS98_RS09385	COG2362	D-Aminopeptidase
FPS98_RS09390	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FPS98_RS09395	COG1960	acyl-CoA dehydrogenase activity
FPS98_RS09450	COG1132	(ABC) transporter
FPS98_RS09455	COG1132	(ABC) transporter
FPS98_RS09475	COG0628	permease
FPS98_RS09480	COG2814	Major facilitator Superfamily
FPS98_RS09495	COG0789	Transcriptional regulator
FPS98_RS09500	COG2814	Major facilitator Superfamily
FPS98_RS09510	COG0488	(ABC) transporter
FPS98_RS09540	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FPS98_RS09545	COG3832	glyoxalase III activity
FPS98_RS09560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FPS98_RS09565	COG4608	Belongs to the ABC transporter superfamily
FPS98_RS09570	COG0444	Belongs to the ABC transporter superfamily
FPS98_RS09575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPS98_RS09595	COG2404	hydrolase activity, acting on ester bonds
FPS98_RS09605	COG0488	(ABC) transporter
FPS98_RS09615	COG2514	catechol 2,3-dioxygenase activity
FPS98_RS09620	COG0247	lactate metabolic process
FPS98_RS09620	COG2181	nitrate reductase activity
FPS98_RS09625	COG1028	Short-chain dehydrogenase reductase Sdr
FPS98_RS09635	COG1960	acyl-CoA dehydrogenase activity
FPS98_RS09650	COG0318	PFAM AMP-dependent synthetase and ligase
FPS98_RS09665	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FPS98_RS09675	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FPS98_RS09685	COG0318	PFAM AMP-dependent synthetase and ligase
FPS98_RS09690	COG1012	belongs to the aldehyde dehydrogenase family
FPS98_RS09705	COG1024	Enoyl-CoA hydratase
FPS98_RS09715	COG3829	transcription factor binding
FPS98_RS09715	COG3290	protein histidine kinase activity
FPS98_RS09720	COG1388	LysM domain
FPS98_RS09730	COG1733	regulation of RNA biosynthetic process
FPS98_RS09735	COG2249	NAD(P)H dehydrogenase (quinone) activity
FPS98_RS09740	COG0346	lactoylglutathione lyase activity
FPS98_RS09790	COG1653	transport
FPS98_RS09795	COG0673	inositol 2-dehydrogenase activity
FPS98_RS09800	COG1082	Xylose isomerase domain protein TIM barrel
FPS98_RS09825	COG1802	Transcriptional regulator
FPS98_RS09830	COG1309	transcriptional regulator
FPS98_RS09840	COG0784	Response regulator, receiver
FPS98_RS09845	COG4191	Histidine kinase
FPS98_RS09850	COG2066	Belongs to the glutaminase family
FPS98_RS09855	COG1115	amino acid carrier protein
FPS98_RS09860	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FPS98_RS09875	COG1024	Enoyl-CoA hydratase
FPS98_RS09880	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FPS98_RS09885	COG1737	Transcriptional regulator
FPS98_RS09890	COG1070	Carbohydrate kinase
FPS98_RS09900	COG0346	lactoylglutathione lyase activity
FPS98_RS09915	COG0067	glutamate synthase
FPS98_RS09915	COG0069	glutamate synthase activity
FPS98_RS09915	COG0070	glutamate synthase
FPS98_RS09920	COG0583	DNA-binding transcription factor activity
FPS98_RS09935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FPS98_RS09950	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FPS98_RS09960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FPS98_RS09980	COG3552	Protein containing von Willebrand factor type A (VWA) domain
FPS98_RS09990	COG0714	Associated with various cellular activities
FPS98_RS09995	COG3483	tryptophan 2,3-dioxygenase activity
FPS98_RS10015	COG0402	S-adenosylhomocysteine deaminase activity
FPS98_RS10020	COG0586	Pfam SNARE associated Golgi protein
FPS98_RS10035	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FPS98_RS10060	COG0109	protoheme IX farnesyltransferase activity
FPS98_RS10090	COG0439	Biotin carboxylase
FPS98_RS10095	COG0511	ligase activity, forming carbon-carbon bonds
FPS98_RS10100	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FPS98_RS10110	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FPS98_RS10110	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FPS98_RS10115	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FPS98_RS10115	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FPS98_RS10120	COG0511	ligase activity, forming carbon-carbon bonds
FPS98_RS10125	COG1309	transcriptional regulator
FPS98_RS10130	COG1876	peptidase activity
FPS98_RS10140	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FPS98_RS10140	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FPS98_RS10145	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FPS98_RS10160	COG0697	spore germination
FPS98_RS10165	COG4946	Tricorn protease homolog
FPS98_RS10165	COG0823	Involved in the tonB-independent uptake of proteins
FPS98_RS10165	COG1506	peptidase
FPS98_RS10170	COG0823	Involved in the tonB-independent uptake of proteins
FPS98_RS10170	COG1506	peptidase
FPS98_RS10175	COG4166	transmembrane transport
FPS98_RS10180	COG4608	Belongs to the ABC transporter superfamily
FPS98_RS10185	COG0444	Belongs to the ABC transporter superfamily
FPS98_RS10190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPS98_RS10195	COG0601	transmembrane transport
FPS98_RS10210	COG0697	spore germination
FPS98_RS10215	COG2755	lipolytic protein G-D-S-L family
FPS98_RS10215	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FPS98_RS10225	COG2132	Multicopper oxidase
FPS98_RS10230	COG1199	ATP-dependent helicase activity
FPS98_RS10240	COG3695	enzyme binding
FPS98_RS10245	COG1164	Oligoendopeptidase f
FPS98_RS10250	COG2309	aminopeptidase activity
FPS98_RS10265	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FPS98_RS10270	COG1984	allophanate hydrolase subunit 2
FPS98_RS10275	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FPS98_RS10280	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FPS98_RS10290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPS98_RS10300	COG0747	negative chemotaxis
FPS98_RS10305	COG4608	Belongs to the ABC transporter superfamily
FPS98_RS10310	COG0444	Belongs to the ABC transporter superfamily
FPS98_RS10315	COG1414	Transcriptional regulator
FPS98_RS10320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FPS98_RS10335	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FPS98_RS10340	COG5002	protein histidine kinase activity
FPS98_RS10350	COG1132	(ABC) transporter
FPS98_RS10395	COG2814	Major facilitator Superfamily
FPS98_RS10405	COG5002	protein histidine kinase activity
FPS98_RS10410	COG0745	RESPONSE REGULATOR receiver
FPS98_RS10420	COG3708	Transcriptional regulator
FPS98_RS10425	COG2378	regulation of single-species biofilm formation
FPS98_RS10440	COG4302	ethanolamine ammonia-lyase activity
FPS98_RS10455	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FPS98_RS10455	COG2169	Transcriptional regulator
FPS98_RS10465	COG1959	2 iron, 2 sulfur cluster binding
FPS98_RS10475	COG0537	adenosine 5'-monophosphoramidase activity
FPS98_RS10480	COG0492	ferredoxin-NADP+ reductase activity
FPS98_RS10485	COG3858	chitin binding
FPS98_RS10490	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FPS98_RS10495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FPS98_RS10515	COG3546	catalase activity
FPS98_RS10525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FPS98_RS10530	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FPS98_RS10560	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FPS98_RS10565	COG2030	dehydratase
FPS98_RS10570	COG0318	PFAM AMP-dependent synthetase and ligase
FPS98_RS10575	COG1309	transcriptional regulator
FPS98_RS10580	COG0791	NLP P60 protein
FPS98_RS10595	COG2720	vancomycin resistance protein
FPS98_RS10620	COG1388	LysM domain
FPS98_RS10620	COG0791	NLP P60 protein
FPS98_RS10620	COG3103	Sh3 type 3 domain protein
FPS98_RS10620	COG1388	LysM domain
FPS98_RS10620	COG3103	Sh3 type 3 domain protein
FPS98_RS10620	COG0791	NLP P60 protein
FPS98_RS10635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FPS98_RS10640	COG3191	aminopeptidase activity
FPS98_RS10645	COG4684	Psort location CytoplasmicMembrane, score
FPS98_RS10650	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FPS98_RS10660	COG1122	ATPase activity
FPS98_RS10685	COG0456	acetyltransferase
FPS98_RS10690	COG3153	acetyltransferase
FPS98_RS10690	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FPS98_RS10710	COG0488	(ABC) transporter
FPS98_RS10725	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FPS98_RS10730	COG2072	flavoprotein involved in K transport
FPS98_RS10740	COG0756	dUTP diphosphatase activity
FPS98_RS10745	COG1054	Belongs to the UPF0176 family
FPS98_RS10750	COG0154	amidase activity
FPS98_RS10765	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FPS98_RS10775	COG3048	D-serine ammonia-lyase activity
FPS98_RS10785	COG0456	acetyltransferase
FPS98_RS10800	COG0564	pseudouridine synthase activity
FPS98_RS10805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FPS98_RS10820	COG0583	DNA-binding transcription factor activity
FPS98_RS10825	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FPS98_RS10830	COG0066	3-isopropylmalate dehydratase activity
FPS98_RS10840	COG0318	PFAM AMP-dependent synthetase and ligase
FPS98_RS10855	COG1666	GTP binding
FPS98_RS10860	COG1028	Short-chain dehydrogenase reductase Sdr
FPS98_RS10870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FPS98_RS10875	COG1164	Oligoendopeptidase f
FPS98_RS10880	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FPS98_RS10885	COG0438	transferase activity, transferring glycosyl groups
FPS98_RS10890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FPS98_RS10895	COG0463	Glycosyl transferase, family 2
FPS98_RS10915	COG3935	DnaD domain protein
FPS98_RS10920	COG0017	Asparaginyl-tRNA synthetase
FPS98_RS10930	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FPS98_RS10955	COG0402	S-adenosylhomocysteine deaminase activity
FPS98_RS10960	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FPS98_RS10970	COG1199	ATP-dependent helicase activity
FPS98_RS10970	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FPS98_RS10980	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FPS98_RS10985	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FPS98_RS10990	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FPS98_RS11000	COG0617	tRNA 3'-terminal CCA addition
FPS98_RS11005	COG0438	transferase activity, transferring glycosyl groups
FPS98_RS11010	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FPS98_RS11015	COG1803	Methylglyoxal synthase
FPS98_RS11020	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FPS98_RS11025	COG1694	Mazg nucleotide pyrophosphohydrolase
FPS98_RS11030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FPS98_RS11050	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FPS98_RS11085	COG1595	DNA-templated transcription, initiation
FPS98_RS11095	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FPS98_RS11100	COG0287	Prephenate dehydrogenase
FPS98_RS11105	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FPS98_RS11110	COG0159	tryptophan synthase activity
FPS98_RS11115	COG0133	tryptophan synthase activity
FPS98_RS11120	COG0135	phosphoribosylanthranilate isomerase activity
FPS98_RS11125	COG0134	indole-3-glycerol-phosphate synthase activity
FPS98_RS11130	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FPS98_RS11145	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FPS98_RS11150	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FPS98_RS11155	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FPS98_RS11160	COG0105	UTP biosynthetic process
FPS98_RS11170	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FPS98_RS11175	COG0163	prenyltransferase activity
FPS98_RS11180	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FPS98_RS11190	COG0142	geranyltranstransferase activity
FPS98_RS11205	COG0741	lytic transglycosylase activity
FPS98_RS11215	COG0302	gtp cyclohydrolase
FPS98_RS11220	COG0776	regulation of translation
FPS98_RS11225	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FPS98_RS11265	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FPS98_RS11270	COG1160	GTP binding
FPS98_RS11290	COG1304	FMN binding
FPS98_RS11295	COG0539	negative regulation of cytoplasmic translation
FPS98_RS11305	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FPS98_RS11320	COG2959	enzyme of heme biosynthesis
FPS98_RS11330	COG2339	peptidase activity
FPS98_RS11345	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FPS98_RS11350	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FPS98_RS11355	COG4862	establishment of competence for transformation
FPS98_RS11375	COG0514	ATP-dependent DNA helicase (RecQ)
FPS98_RS11390	COG1141	Ferredoxin
FPS98_RS11400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FPS98_RS11405	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FPS98_RS11420	COG5002	protein histidine kinase activity
FPS98_RS11425	COG0745	RESPONSE REGULATOR receiver
FPS98_RS11430	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FPS98_RS11435	COG1333	cytochrome c biogenesis protein
FPS98_RS11440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FPS98_RS11445	COG1187	pseudouridine synthase activity
FPS98_RS11450	COG0700	Nucleoside recognition
FPS98_RS11455	COG2715	membrane protein required for spore maturation
FPS98_RS11460	COG1686	Belongs to the peptidase S11 family
FPS98_RS11465	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FPS98_RS11470	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FPS98_RS11475	COG1994	Peptidase M50
FPS98_RS11480	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FPS98_RS11485	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FPS98_RS11495	COG0697	spore germination
FPS98_RS11510	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FPS98_RS11535	COG2172	sigma factor antagonist activity
FPS98_RS11545	COG1686	Belongs to the peptidase S11 family
FPS98_RS11550	COG0840	transmembrane signaling receptor activity
FPS98_RS11555	COG4608	Belongs to the ABC transporter superfamily
FPS98_RS11560	COG0444	Belongs to the ABC transporter superfamily
FPS98_RS11565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPS98_RS11570	COG0601	transmembrane transport
FPS98_RS11575	COG4166	transmembrane transport
FPS98_RS11580	COG1522	sequence-specific DNA binding
FPS98_RS11585	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FPS98_RS11595	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FPS98_RS11600	COG4974	Belongs to the 'phage' integrase family
FPS98_RS11610	COG0735	belongs to the Fur family
FPS98_RS11615	COG1300	Membrane
FPS98_RS11620	COG1379	DNA repair
FPS98_RS11625	COG0494	nUDIX hydrolase
FPS98_RS11640	COG2195	Cleaves the N-terminal amino acid of tripeptides
FPS98_RS11645	COG0346	lactoylglutathione lyase activity
FPS98_RS11655	COG0508	dehydrogenase complex catalyzes the overall conversion of
FPS98_RS11660	COG0022	dehydrogenase e1 component
FPS98_RS11665	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FPS98_RS11670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FPS98_RS11675	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FPS98_RS11680	COG3829	transcription factor binding
FPS98_RS11680	COG3290	protein histidine kinase activity
FPS98_RS11695	COG0463	Glycosyl transferase, family 2
FPS98_RS11725	COG2226	methyltransferase
FPS98_RS11730	COG0583	DNA-binding transcription factor activity
FPS98_RS11735	COG1408	metallophosphoesterase
FPS98_RS11740	COG0288	reversible hydration of carbon dioxide
FPS98_RS11770	COG0750	zinc metalloprotease
FPS98_RS11775	COG0497	DNA recombination
FPS98_RS11780	COG1438	arginine binding
FPS98_RS11785	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FPS98_RS11790	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FPS98_RS11795	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FPS98_RS11805	COG0142	geranyltranstransferase activity
FPS98_RS11815	COG1570	exodeoxyribonuclease VII activity
FPS98_RS11820	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FPS98_RS11825	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FPS98_RS11830	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FPS98_RS11845	COG1302	Protein conserved in bacteria
FPS98_RS11850	COG0439	Biotin carboxylase
FPS98_RS11855	COG0511	ligase activity, forming carbon-carbon bonds
FPS98_RS11895	COG3854	ATPases associated with a variety of cellular activities
FPS98_RS11910	COG1809	phosphosulfolactate synthase activity
FPS98_RS11920	COG2707	UPF0756 membrane protein
FPS98_RS11935	COG1595	DNA-templated transcription, initiation
FPS98_RS11945	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FPS98_RS11950	COG0006	proline dipeptidase activity
FPS98_RS11955	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FPS98_RS11965	COG3872	metal-dependent enzyme
FPS98_RS11975	COG1752	Esterase of the alpha-beta hydrolase superfamily
FPS98_RS11980	COG1321	iron dependent repressor
FPS98_RS11985	COG0431	NADPH-dependent FMN reductase
FPS98_RS11995	COG2234	aminopeptidase activity
FPS98_RS12005	COG0095	Lipoate-protein ligase
FPS98_RS12010	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FPS98_RS12015	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FPS98_RS12020	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FPS98_RS12030	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FPS98_RS12055	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FPS98_RS12065	COG1910	domain protein
FPS98_RS12070	COG0725	ABC transporter, periplasmic molybdate-binding protein
FPS98_RS12075	COG4149	molybdate abc transporter
FPS98_RS12080	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FPS98_RS12085	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FPS98_RS12100	COG3679	Belongs to the UPF0342 family
FPS98_RS12120	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FPS98_RS12135	COG3546	catalase activity
FPS98_RS12170	COG0444	Belongs to the ABC transporter superfamily
FPS98_RS12175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPS98_RS12180	COG0601	transmembrane transport
FPS98_RS12190	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FPS98_RS12205	COG5001	Diguanylate cyclase
FPS98_RS12205	COG3300	MHYT domain
FPS98_RS12215	COG0840	transmembrane signaling receptor activity
FPS98_RS12215	COG5278	phosphoserine phosphatase activity
FPS98_RS12220	COG1525	nuclease
FPS98_RS12225	COG2226	methyltransferase
FPS98_RS12230	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FPS98_RS12240	COG0772	Belongs to the SEDS family
FPS98_RS12250	COG0028	Belongs to the TPP enzyme family
FPS98_RS12270	COG0733	neurotransmitter:sodium symporter activity
FPS98_RS12275	COG4838	Belongs to the UPF0358 family
FPS98_RS12285	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FPS98_RS12290	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FPS98_RS12295	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FPS98_RS12305	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FPS98_RS12310	COG3829	transcription factor binding
FPS98_RS12315	COG0833	amino acid
FPS98_RS12320	COG0477	Major facilitator Superfamily
FPS98_RS12325	COG0583	DNA-binding transcription factor activity
FPS98_RS12330	COG0671	phosphoesterase, PA-phosphatase related
FPS98_RS12335	COG1671	Belongs to the UPF0178 family
FPS98_RS12345	COG1404	Belongs to the peptidase S8 family
FPS98_RS12370	COG1234	tRNA 3'-trailer cleavage
FPS98_RS12375	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FPS98_RS12380	COG1116	anion transmembrane transporter activity
FPS98_RS12385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FPS98_RS12390	COG0346	lactoylglutathione lyase activity
FPS98_RS12440	COG3739	integral membrane protein
FPS98_RS12445	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FPS98_RS12455	COG1396	sequence-specific DNA binding
FPS98_RS12460	COG0006	proline dipeptidase activity
FPS98_RS12465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FPS98_RS12475	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FPS98_RS12480	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FPS98_RS12485	COG0300	oxidoreductase activity
FPS98_RS12500	COG0646	methionine synthase
FPS98_RS12500	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FPS98_RS12520	COG1595	DNA-templated transcription, initiation
FPS98_RS12535	COG0018	arginyl-trna synthetase
FPS98_RS12540	COG0183	Belongs to the thiolase family
FPS98_RS12545	COG1126	abc transporter atp-binding protein
FPS98_RS12550	COG0765	amino acid transport
FPS98_RS12555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FPS98_RS12560	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FPS98_RS12565	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FPS98_RS12580	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FPS98_RS12610	COG4667	esterase of the alpha-beta hydrolase superfamily
FPS98_RS12620	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FPS98_RS12625	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FPS98_RS12630	COG3162	membrane
FPS98_RS12635	COG3279	Response regulator of the LytR AlgR family
FPS98_RS12640	COG3275	phosphorelay sensor kinase activity
FPS98_RS12645	COG0367	asparagine synthase
FPS98_RS12655	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FPS98_RS12660	COG0243	molybdopterin cofactor binding
FPS98_RS12675	COG2373	Large extracellular alpha-helical protein
FPS98_RS12690	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FPS98_RS12705	COG0535	radical SAM domain protein
FPS98_RS12715	COG0477	Major facilitator Superfamily
FPS98_RS12730	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FPS98_RS12760	COG1119	ATPase activity
FPS98_RS12790	COG5001	Diguanylate cyclase
FPS98_RS12790	COG3300	MHYT domain
FPS98_RS12795	COG4294	response to UV
FPS98_RS12815	COG2986	histidine ammonia-lyase
FPS98_RS12820	COG3011	Protein conserved in bacteria
FPS98_RS12830	COG0667	Aldo Keto reductase
FPS98_RS12835	COG1607	acyl-coa hydrolase
FPS98_RS12850	COG2154	pterin-4-alpha-carbinolamine dehydratase
FPS98_RS12870	COG1428	Deoxynucleoside kinase
FPS98_RS12875	COG1428	Deoxynucleoside kinase
FPS98_RS12890	COG1595	DNA-templated transcription, initiation
FPS98_RS12900	COG0351	phosphomethylpyrimidine kinase
FPS98_RS12905	COG3850	Histidine kinase
FPS98_RS12910	COG2197	response regulator
FPS98_RS12930	COG0701	Predicted permease
FPS98_RS12940	COG2072	flavoprotein involved in K transport
FPS98_RS12950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FPS98_RS12955	COG1408	metallophosphoesterase
FPS98_RS12960	COG3835	regulator
FPS98_RS12965	COG3842	ATPase activity
FPS98_RS12970	COG0561	phosphatase activity
FPS98_RS12985	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FPS98_RS13000	COG0745	RESPONSE REGULATOR receiver
FPS98_RS13040	COG1309	transcriptional regulator
FPS98_RS13060	COG3876	Protein conserved in bacteria
FPS98_RS13065	COG0318	PFAM AMP-dependent synthetase and ligase
FPS98_RS13075	COG1012	belongs to the aldehyde dehydrogenase family
FPS98_RS13080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FPS98_RS13085	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FPS98_RS13090	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FPS98_RS13095	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FPS98_RS13105	COG0456	acetyltransferase
FPS98_RS13115	COG0584	glycerophosphoryl diester phosphodiesterase
FPS98_RS13120	COG1242	4 iron, 4 sulfur cluster binding
FPS98_RS13185	COG3409	Peptidoglycan-binding domain 1 protein
FPS98_RS13185	COG0793	Belongs to the peptidase S41A family
FPS98_RS13195	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FPS98_RS13200	COG2384	SAM-dependent methyltransferase
FPS98_RS13210	COG1960	acyl-CoA dehydrogenase activity
FPS98_RS13220	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FPS98_RS13225	COG0358	DNA primase activity
FPS98_RS13230	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FPS98_RS13235	COG0517	IMP dehydrogenase activity
FPS98_RS13240	COG0751	glycine-tRNA ligase activity
FPS98_RS13245	COG0752	glycyl-tRNA synthetase alpha subunit
FPS98_RS13250	COG1381	Involved in DNA repair and RecF pathway recombination
FPS98_RS13260	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FPS98_RS13265	COG0295	cytidine deaminase activity
FPS98_RS13270	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FPS98_RS13275	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FPS98_RS13280	COG1702	phosphate starvation-inducible protein PhoH
FPS98_RS13305	COG4864	UPF0365 protein
FPS98_RS13310	COG1030	water channel activity
FPS98_RS13315	COG1610	YqeY-like protein
FPS98_RS13320	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FPS98_RS13325	COG0537	adenosine 5'-monophosphoramidase activity
FPS98_RS13330	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FPS98_RS13340	COG1082	Xylose isomerase domain protein TIM barrel
FPS98_RS13350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FPS98_RS13375	COG1181	Belongs to the D-alanine--D-alanine ligase family
FPS98_RS13395	COG1283	sodium-dependent phosphate transmembrane transporter activity
FPS98_RS13400	COG1346	cytolysis
FPS98_RS13410	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FPS98_RS13420	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FPS98_RS13425	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FPS98_RS13430	COG2264	protein methyltransferase activity
FPS98_RS13435	COG0484	heat shock protein binding
FPS98_RS13440	COG0443	Heat shock 70 kDa protein
FPS98_RS13450	COG1420	regulation of RNA biosynthetic process
FPS98_RS13455	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FPS98_RS13460	COG0481	GTPase activity
FPS98_RS13465	COG0537	adenosine 5'-monophosphoramidase activity
FPS98_RS13485	COG2226	methyltransferase
FPS98_RS13500	COG2964	Protein conserved in bacteria
FPS98_RS13510	COG1120	ATPase activity
FPS98_RS13515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPS98_RS13525	COG0006	proline dipeptidase activity
FPS98_RS13535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPS98_RS13540	COG0601	transmembrane transport
FPS98_RS13545	COG0747	negative chemotaxis
FPS98_RS13550	COG4608	Belongs to the ABC transporter superfamily
FPS98_RS13555	COG0444	Belongs to the ABC transporter superfamily
FPS98_RS13565	COG0860	N-Acetylmuramoyl-L-alanine amidase
FPS98_RS13575	COG0268	Binds directly to 16S ribosomal RNA
FPS98_RS13580	COG1466	dna polymerase III delta subunit
FPS98_RS13595	COG0658	competence protein
FPS98_RS13595	COG2333	competence protein COMEC
FPS98_RS13600	COG0367	asparagine synthase
FPS98_RS13605	COG1555	photosystem II stabilization
FPS98_RS13605	COG1596	polysaccharide export
FPS98_RS13610	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FPS98_RS13615	COG0495	leucyl-tRNA aminoacylation
FPS98_RS13620	COG2226	methyltransferase
FPS98_RS13625	COG0799	negative regulation of ribosome biogenesis
FPS98_RS13630	COG1713	HD superfamily hydrolase involved in NAD metabolism
FPS98_RS13635	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FPS98_RS13640	COG1534	Rna-binding protein
FPS98_RS13645	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FPS98_RS13650	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FPS98_RS13655	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FPS98_RS13680	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FPS98_RS13685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FPS98_RS13695	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FPS98_RS13700	COG4166	transmembrane transport
FPS98_RS13710	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
FPS98_RS13715	COG1413	lyase activity
FPS98_RS13735	COG1376	ErfK ybiS ycfS ynhG family protein
FPS98_RS13745	COG0488	(ABC) transporter
FPS98_RS13750	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FPS98_RS13760	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FPS98_RS13770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FPS98_RS13775	COG3336	cytochrome c oxidase
FPS98_RS13795	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FPS98_RS13810	COG1329	Transcriptional regulator
FPS98_RS13885	COG0456	acetyltransferase
FPS98_RS13890	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FPS98_RS13945	COG0739	heme binding
FPS98_RS14055	COG0443	Heat shock 70 kDa protein
FPS98_RS14070	COG1280	lysine exporter protein (LysE YggA)
FPS98_RS14075	COG1247	-acetyltransferase
FPS98_RS14090	COG0768	penicillin binding
FPS98_RS14095	COG0572	uridine kinase
FPS98_RS14100	COG4122	O-methyltransferase activity
FPS98_RS14105	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FPS98_RS14110	COG3906	Belongs to the UPF0473 family
FPS98_RS14120	COG4472	Bacterial protein of unknown function (DUF965)
FPS98_RS14125	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FPS98_RS14130	COG0628	permease
FPS98_RS14135	COG0861	Integral membrane protein TerC family
FPS98_RS14155	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FPS98_RS14160	COG0840	transmembrane signaling receptor activity
FPS98_RS14165	COG1104	cysteine desulfurase activity
FPS98_RS14170	COG1959	2 iron, 2 sulfur cluster binding
FPS98_RS14180	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FPS98_RS14190	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FPS98_RS14195	COG0124	histidyl-tRNA synthetase
FPS98_RS14200	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FPS98_RS14205	COG4991	sh3 domain protein
FPS98_RS14205	COG3103	Sh3 type 3 domain protein
FPS98_RS14205	COG0860	N-Acetylmuramoyl-L-alanine amidase
FPS98_RS14210	COG2801	Transposase and inactivated derivatives
FPS98_RS14215	COG2318	DinB family
FPS98_RS14225	COG1490	D-aminoacyl-tRNA deacylase activity
FPS98_RS14230	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FPS98_RS14235	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FPS98_RS14240	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FPS98_RS14240	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FPS98_RS14245	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FPS98_RS14245	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FPS98_RS14250	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FPS98_RS14250	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FPS98_RS14260	COG2244	polysaccharide biosynthetic process
FPS98_RS14265	COG2323	membrane
FPS98_RS14270	COG0598	Magnesium transport protein CorA
FPS98_RS14280	COG1862	Preprotein translocase
FPS98_RS14290	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FPS98_RS14295	COG2385	sporulation resulting in formation of a cellular spore
FPS98_RS14305	COG2255	four-way junction helicase activity
FPS98_RS14310	COG0632	four-way junction helicase activity
FPS98_RS14315	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FPS98_RS14335	COG0737	Belongs to the 5'-nucleotidase family
FPS98_RS14345	COG1388	LysM domain
FPS98_RS14350	COG0077	Prephenate dehydratase
FPS98_RS14360	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FPS98_RS14365	COG0460	homoserine dehydrogenase
FPS98_RS14370	COG4492	Belongs to the UPF0735 family
FPS98_RS14375	COG1252	NADH dehydrogenase
FPS98_RS14390	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FPS98_RS14400	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FPS98_RS14410	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FPS98_RS14415	COG1530	ribonuclease E activity
FPS98_RS14425	COG1994	Peptidase M50
FPS98_RS14435	COG1278	Cold shock
FPS98_RS14440	COG0772	Belongs to the SEDS family
FPS98_RS14445	COG2894	cell division
FPS98_RS14450	COG0850	regulation of cytokinetic process
FPS98_RS14455	COG0768	penicillin binding
FPS98_RS14460	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FPS98_RS14465	COG1792	Involved in formation and maintenance of cell shape
FPS98_RS14470	COG1077	Cell shape determining protein MreB Mrl
FPS98_RS14475	COG2003	Belongs to the UPF0758 family
FPS98_RS14480	COG0424	maF-like protein
FPS98_RS14500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FPS98_RS14505	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FPS98_RS14510	COG0285	dihydrofolate synthase activity
FPS98_RS14515	COG0525	valine-tRNA ligase activity
FPS98_RS14550	COG1388	LysM domain
FPS98_RS14555	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FPS98_RS14560	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FPS98_RS14565	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FPS98_RS14580	COG1695	Transcriptional regulator
FPS98_RS14585	COG0737	Belongs to the 5'-nucleotidase family
FPS98_RS14590	COG2267	carboxylic ester hydrolase activity
FPS98_RS14605	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FPS98_RS14610	COG0113	porphobilinogen synthase activity
FPS98_RS14620	COG0181	hydroxymethylbilane synthase activity
FPS98_RS14625	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FPS98_RS14630	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FPS98_RS14640	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FPS98_RS14640	COG3291	Pkd domain containing protein
FPS98_RS14645	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FPS98_RS14655	COG1067	ATP-dependent peptidase activity
FPS98_RS14655	COG0470	DNA polymerase III
FPS98_RS14660	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FPS98_RS14665	COG0740	serine-type endopeptidase activity
FPS98_RS14670	COG0544	peptidyl-prolyl cis-trans isomerase activity
FPS98_RS14675	COG0622	Phosphoesterase
FPS98_RS14680	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FPS98_RS14685	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FPS98_RS14700	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FPS98_RS14705	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FPS98_RS14720	COG1595	DNA-templated transcription, initiation
FPS98_RS14730	COG0456	acetyltransferase
FPS98_RS14760	COG3209	COG3209 Rhs family protein
FPS98_RS14800	COG3209	COG3209 Rhs family protein
FPS98_RS14810	COG0384	phenazine biosynthesis protein PhzF
FPS98_RS14815	COG0583	DNA-binding transcription factor activity
FPS98_RS14825	COG4608	Belongs to the ABC transporter superfamily
FPS98_RS14830	COG0444	Belongs to the ABC transporter superfamily
FPS98_RS14835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPS98_RS14840	COG0601	transmembrane transport
FPS98_RS14845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FPS98_RS14850	COG3290	protein histidine kinase activity
FPS98_RS14850	COG3829	transcription factor binding
FPS98_RS14855	COG4166	transmembrane transport
FPS98_RS14870	COG0463	Glycosyl transferase, family 2
FPS98_RS14870	COG1216	Glycosyl transferase, family 2
FPS98_RS14875	COG0562	UDP-galactopyranose mutase
FPS98_RS14880	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FPS98_RS14900	COG1442	glycosyl transferase family 8
FPS98_RS14900	COG1216	Glycosyl transferase, family 2
FPS98_RS14905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FPS98_RS14940	COG0662	Cupin 2, conserved barrel domain protein
FPS98_RS14940	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FPS98_RS14950	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FPS98_RS14955	COG1216	Glycosyl transferase, family 2
FPS98_RS14965	COG2340	Cysteine-rich secretory protein family
FPS98_RS14975	COG0463	Glycosyl transferase, family 2
FPS98_RS15010	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FPS98_RS15025	COG1378	Sugar-specific transcriptional regulator TrmB
FPS98_RS15030	COG2814	Major facilitator Superfamily
FPS98_RS15035	COG3290	protein histidine kinase activity
FPS98_RS15040	COG1473	amidohydrolase
FPS98_RS15050	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FPS98_RS15065	COG1940	carbohydrate kinase activity
FPS98_RS15085	COG0673	inositol 2-dehydrogenase activity
FPS98_RS15090	COG0395	ABC-type sugar transport system, permease component
FPS98_RS15095	COG1175	transmembrane transport
FPS98_RS15175	COG2197	response regulator
FPS98_RS15185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPS98_RS15190	COG0601	transmembrane transport
FPS98_RS15210	COG1846	Transcriptional regulator
FPS98_RS15215	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FPS98_RS15220	COG1053	succinate dehydrogenase
FPS98_RS15225	COG2009	succinate dehydrogenase
FPS98_RS15240	COG0322	excinuclease ABC activity
FPS98_RS15270	COG0683	leucine binding
FPS98_RS15275	COG3118	belongs to the thioredoxin family
FPS98_RS15285	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FPS98_RS15290	COG2086	electron transfer activity
FPS98_RS15295	COG1024	Enoyl-CoA hydratase
FPS98_RS15300	COG1309	transcriptional regulator
FPS98_RS15305	COG0318	PFAM AMP-dependent synthetase and ligase
FPS98_RS15310	COG1316	TRANSCRIPTIONal
FPS98_RS15315	COG0183	Belongs to the thiolase family
FPS98_RS15320	COG2264	protein methyltransferase activity
FPS98_RS15335	COG2244	polysaccharide biosynthetic process
FPS98_RS15370	COG0438	transferase activity, transferring glycosyl groups
FPS98_RS15375	COG2362	D-Aminopeptidase
FPS98_RS15385	COG1278	Cold shock
FPS98_RS15395	COG1595	DNA-templated transcription, initiation
FPS98_RS15400	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FPS98_RS15405	COG3766	membrane
FPS98_RS15410	COG1193	negative regulation of DNA recombination
FPS98_RS15420	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FPS98_RS15430	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FPS98_RS15440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FPS98_RS15445	COG0569	domain protein
FPS98_RS15455	COG0814	amino acid
FPS98_RS15465	COG0814	amino acid
FPS98_RS15470	COG0697	spore germination
FPS98_RS15475	COG3844	kynureninase activity
FPS98_RS15485	COG0586	Pfam SNARE associated Golgi protein
FPS98_RS15505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FPS98_RS15510	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FPS98_RS15515	COG0473	3-isopropylmalate dehydrogenase activity
FPS98_RS15520	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FPS98_RS15525	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FPS98_RS15530	COG0440	acetolactate synthase activity
FPS98_RS15535	COG0028	Belongs to the TPP enzyme family
FPS98_RS15540	COG2046	Belongs to the sulfate adenylyltransferase family
FPS98_RS15545	COG0175	sulfate reduction
FPS98_RS15560	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FPS98_RS15570	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FPS98_RS15575	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FPS98_RS15580	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FPS98_RS15585	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FPS98_RS15590	COG0840	transmembrane signaling receptor activity
FPS98_RS15595	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FPS98_RS15605	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FPS98_RS15620	COG1960	acyl-CoA dehydrogenase activity
FPS98_RS15625	COG0318	PFAM AMP-dependent synthetase and ligase
FPS98_RS15635	COG3773	Cell wall hydrolase
FPS98_RS15665	COG0477	Major facilitator Superfamily
FPS98_RS15670	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FPS98_RS15675	COG0747	negative chemotaxis
FPS98_RS15680	COG0402	S-adenosylhomocysteine deaminase activity
FPS98_RS15685	COG0747	negative chemotaxis
FPS98_RS15700	COG0747	negative chemotaxis
FPS98_RS15710	COG2186	Transcriptional regulator
FPS98_RS15715	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FPS98_RS15720	COG1028	Short-chain dehydrogenase reductase Sdr
FPS98_RS15725	COG0402	S-adenosylhomocysteine deaminase activity
FPS98_RS15730	COG0402	S-adenosylhomocysteine deaminase activity
FPS98_RS15735	COG0861	Integral membrane protein TerC family
FPS98_RS15760	COG2814	Major facilitator Superfamily
FPS98_RS15765	COG0583	DNA-binding transcription factor activity
FPS98_RS15770	COG0477	Major facilitator Superfamily
FPS98_RS15775	COG0583	DNA-binding transcription factor activity
FPS98_RS15790	COG0577	efflux transmembrane transporter activity
FPS98_RS15790	COG1136	(ABC) transporter
FPS98_RS15805	COG1136	(ABC) transporter
FPS98_RS15810	COG0402	S-adenosylhomocysteine deaminase activity
FPS98_RS15815	COG0402	S-adenosylhomocysteine deaminase activity
FPS98_RS15820	COG0402	S-adenosylhomocysteine deaminase activity
FPS98_RS15825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPS98_RS15830	COG0601	transmembrane transport
FPS98_RS15835	COG0444	Belongs to the ABC transporter superfamily
FPS98_RS15840	COG4608	Belongs to the ABC transporter superfamily
FPS98_RS15845	COG2972	Histidine kinase
FPS98_RS15850	COG1917	Cupin 2, conserved barrel domain protein
FPS98_RS15850	COG4977	sequence-specific DNA binding
FPS98_RS15875	COG0395	ABC-type sugar transport system, permease component
FPS98_RS15880	COG1175	transmembrane transport
FPS98_RS15905	COG1012	belongs to the aldehyde dehydrogenase family
FPS98_RS15920	COG2267	carboxylic ester hydrolase activity
FPS98_RS15935	COG0583	DNA-binding transcription factor activity
FPS98_RS15945	COG1309	transcriptional regulator
FPS98_RS15950	COG0673	inositol 2-dehydrogenase activity
FPS98_RS15975	COG2814	Major facilitator Superfamily
FPS98_RS16025	COG1051	belongs to the nudix hydrolase family
FPS98_RS16050	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FPS98_RS16055	COG0247	lactate metabolic process
FPS98_RS16060	COG0277	FAD linked oxidase domain protein
FPS98_RS16065	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FPS98_RS16070	COG4608	Belongs to the ABC transporter superfamily
FPS98_RS16075	COG0444	Belongs to the ABC transporter superfamily
FPS98_RS16085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPS98_RS16095	COG0747	negative chemotaxis
FPS98_RS16100	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FPS98_RS16125	COG1970	mechanosensitive ion channel activity
FPS98_RS16150	COG0577	efflux transmembrane transporter activity
FPS98_RS16150	COG1136	(ABC) transporter
FPS98_RS16155	COG1136	(ABC) transporter
FPS98_RS16170	COG5002	protein histidine kinase activity
FPS98_RS16175	COG0745	RESPONSE REGULATOR receiver
FPS98_RS16180	COG0778	Nitroreductase
FPS98_RS16195	COG1643	Atp-dependent helicase
FPS98_RS16205	COG4196	transglutaminase domain protein
FPS98_RS16210	COG2323	membrane
FPS98_RS16215	COG0346	lactoylglutathione lyase activity
FPS98_RS16220	COG3428	Bacterial PH domain
FPS98_RS16230	COG0450	alkyl hydroperoxide reductase
FPS98_RS16240	COG0330	HflC and HflK could
FPS98_RS16255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPS98_RS16260	COG2226	methyltransferase
FPS98_RS16265	COG1132	(ABC) transporter
FPS98_RS16270	COG1132	(ABC) transporter
FPS98_RS16290	COG1695	Transcriptional regulator
FPS98_RS16305	COG1595	DNA-templated transcription, initiation
FPS98_RS16310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FPS98_RS16325	COG0217	transcriptional regulatory protein
FPS98_RS16330	COG0803	Belongs to the bacterial solute-binding protein 9 family
FPS98_RS16335	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FPS98_RS16340	COG1121	(ABC) transporter
FPS98_RS16345	COG1113	amino acid transport
FPS98_RS16355	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FPS98_RS16385	COG0326	Molecular chaperone. Has ATPase activity
FPS98_RS16390	COG1733	regulation of RNA biosynthetic process
FPS98_RS16400	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FPS98_RS16420	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FPS98_RS16430	COG1063	alcohol dehydrogenase
FPS98_RS16445	COG1129	ABC transporter
FPS98_RS16480	COG2311	Membrane
FPS98_RS16500	COG1307	EDD domain protein, DegV family
FPS98_RS16505	COG1063	alcohol dehydrogenase
FPS98_RS16525	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FPS98_RS16555	COG2814	Major facilitator Superfamily
FPS98_RS16560	COG2814	Major facilitator Superfamily
FPS98_RS16565	COG1846	Transcriptional regulator
FPS98_RS16590	COG2249	NAD(P)H dehydrogenase (quinone) activity
FPS98_RS16600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FPS98_RS16605	COG2207	Transcriptional regulator
FPS98_RS16605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FPS98_RS16665	COG0477	Major facilitator Superfamily
FPS98_RS16670	COG3275	phosphorelay sensor kinase activity
FPS98_RS16675	COG3279	Response regulator of the LytR AlgR family
FPS98_RS16690	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FPS98_RS16755	COG1484	DNA-dependent DNA replication
FPS98_RS16765	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FPS98_RS16775	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FPS98_RS16785	COG0237	dephospho-CoA kinase activity
FPS98_RS16790	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FPS98_RS16795	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FPS98_RS16795	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FPS98_RS16800	COG2861	carbohydrate metabolic process
FPS98_RS16805	COG0860	N-Acetylmuramoyl-L-alanine amidase
FPS98_RS16815	COG2814	Major facilitator Superfamily
FPS98_RS16820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FPS98_RS16825	COG1566	PFAM secretion protein HlyD family protein
FPS98_RS16830	COG1846	Transcriptional regulator
FPS98_RS16840	COG2720	vancomycin resistance protein
FPS98_RS16850	COG0704	Plays a role in the regulation of phosphate uptake
FPS98_RS16855	COG5002	protein histidine kinase activity
FPS98_RS16860	COG0745	RESPONSE REGULATOR receiver
FPS98_RS16865	COG0039	L-malate dehydrogenase activity
FPS98_RS16870	COG0538	isocitrate dehydrogenase activity
FPS98_RS16875	COG0372	Belongs to the citrate synthase family
FPS98_RS16880	COG0628	permease
FPS98_RS16890	COG0824	Thioesterase
FPS98_RS16900	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FPS98_RS16910	COG0205	6-phosphofructokinase activity
FPS98_RS16915	COG0825	malonyl-CoA metabolic process
FPS98_RS16920	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FPS98_RS16930	COG2186	Transcriptional regulator
FPS98_RS16935	COG0281	malic enzyme
FPS98_RS16940	COG0587	DNA-directed DNA polymerase activity
FPS98_RS16950	COG0640	Transcriptional regulator
FPS98_RS16955	COG2207	Transcriptional regulator
FPS98_RS16965	COG4109	DRTGG domain
FPS98_RS16970	COG4399	Belongs to the UPF0754 family
FPS98_RS16975	COG0189	ligase activity
FPS98_RS16980	COG0189	ligase activity
FPS98_RS16985	COG0189	ligase activity
FPS98_RS16990	COG0189	ligase activity
FPS98_RS17020	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FPS98_RS17030	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FPS98_RS17040	COG0745	RESPONSE REGULATOR receiver
FPS98_RS17045	COG1215	transferase activity, transferring glycosyl groups
FPS98_RS17060	COG0492	ferredoxin-NADP+ reductase activity
FPS98_RS17065	COG0450	alkyl hydroperoxide reductase
FPS98_RS17075	COG0492	ferredoxin-NADP+ reductase activity
FPS98_RS17080	COG1757	Na H antiporter
FPS98_RS17085	COG3706	GGDEF domain
FPS98_RS17095	COG4191	Histidine kinase
FPS98_RS17100	COG2971	BadF BadG BcrA BcrD
FPS98_RS17105	COG0395	ABC-type sugar transport system, permease component
FPS98_RS17110	COG1175	transmembrane transport
FPS98_RS17115	COG2182	Extracellular solute-binding protein
FPS98_RS17120	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FPS98_RS17125	COG1737	Transcriptional regulator
FPS98_RS17130	COG0402	S-adenosylhomocysteine deaminase activity
FPS98_RS17145	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FPS98_RS17165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPS98_RS17170	COG1120	ATPase activity
FPS98_RS17175	COG0748	coenzyme F420 binding
FPS98_RS17230	COG0180	Tryptophanyl-tRNA synthetase
FPS98_RS17240	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FPS98_RS17245	COG1309	transcriptional regulator
FPS98_RS17255	COG0028	Belongs to the TPP enzyme family
FPS98_RS17290	COG0583	DNA-binding transcription factor activity
FPS98_RS17295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FPS98_RS17300	COG1683	Conserved Protein
FPS98_RS17305	COG1072	(Pantothenic acid kinase))
FPS98_RS17310	COG0783	Belongs to the Dps family
FPS98_RS17455	COG1619	proteins homologs of microcin C7 resistance protein MccF
FPS98_RS17460	COG3829	transcription factor binding
FPS98_RS17465	COG4565	transcriptional regulatory protein
FPS98_RS17470	COG3290	protein histidine kinase activity
FPS98_RS17475	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FPS98_RS17480	COG5002	protein histidine kinase activity
FPS98_RS17485	COG0745	RESPONSE REGULATOR receiver
FPS98_RS17495	COG1301	dicarboxylic acid transport
FPS98_RS17505	COG0490	domain, Protein
FPS98_RS17510	COG0475	glutathione-regulated potassium exporter activity
FPS98_RS17515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FPS98_RS17525	COG0456	acetyltransferase
FPS98_RS17530	COG1648	precorrin-2 dehydrogenase activity
FPS98_RS17530	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FPS98_RS17535	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FPS98_RS17540	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FPS98_RS17545	COG1492	cobalamin metabolic process
FPS98_RS17575	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FPS98_RS17600	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FPS98_RS17605	COG0406	alpha-ribazole phosphatase activity
FPS98_RS17610	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FPS98_RS17620	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FPS98_RS17625	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FPS98_RS17635	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FPS98_RS17645	COG2707	UPF0756 membrane protein
FPS98_RS17670	COG0450	alkyl hydroperoxide reductase
FPS98_RS17675	COG0069	glutamate synthase activity
FPS98_RS17705	COG0784	Response regulator, receiver
FPS98_RS17710	COG4191	Histidine kinase
FPS98_RS17715	COG0765	amino acid transport
FPS98_RS17720	COG0765	amino acid transport
FPS98_RS17735	COG1595	DNA-templated transcription, initiation
FPS98_RS17745	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
FPS98_RS17755	COG2814	Major facilitator Superfamily
FPS98_RS17765	COG2814	Major facilitator Superfamily
FPS98_RS17820	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FPS98_RS17825	COG1845	cytochrome c oxidase, subunit III
FPS98_RS17830	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FPS98_RS17845	COG3290	protein histidine kinase activity
FPS98_RS17850	COG4565	transcriptional regulatory protein
FPS98_RS17855	COG0697	spore germination
FPS98_RS17860	COG1522	sequence-specific DNA binding
FPS98_RS17865	COG2226	methyltransferase
FPS98_RS17880	COG3181	Tripartite tricarboxylate transporter family receptor
FPS98_RS17890	COG0583	DNA-binding transcription factor activity
FPS98_RS17895	COG0861	Integral membrane protein TerC family
FPS98_RS17940	COG0840	transmembrane signaling receptor activity
FPS98_RS17945	COG1250	3-hydroxyacyl-CoA dehydrogenase
FPS98_RS17950	COG1028	Short-chain dehydrogenase reductase Sdr
FPS98_RS17955	COG1028	Short-chain dehydrogenase reductase Sdr
FPS98_RS17960	COG2719	SpoVR family
FPS98_RS17970	COG2363	Small membrane protein
FPS98_RS17980	COG3973	AAA domain
FPS98_RS17985	COG2259	Doxx family
FPS98_RS17995	COG2814	Major facilitator Superfamily
FPS98_RS18005	COG1988	membrane-bound metal-dependent
FPS98_RS18015	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FPS98_RS18020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FPS98_RS18030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FPS98_RS18045	COG1763	Mo-molybdopterin cofactor biosynthetic process
FPS98_RS18050	COG0303	'Molybdopterin
FPS98_RS18065	COG2223	nitrite transmembrane transporter activity
FPS98_RS18070	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FPS98_RS18080	COG0746	molybdenum cofactor guanylyltransferase activity
FPS98_RS18145	COG0833	amino acid
FPS98_RS18165	COG0436	Aminotransferase
FPS98_RS18170	COG1522	sequence-specific DNA binding
FPS98_RS18175	COG5002	protein histidine kinase activity
FPS98_RS18180	COG0745	RESPONSE REGULATOR receiver
FPS98_RS18195	COG1335	isochorismatase
FPS98_RS18200	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FPS98_RS18205	COG0697	spore germination
FPS98_RS18210	COG3300	MHYT domain
FPS98_RS18210	COG5001	Diguanylate cyclase
FPS98_RS18250	COG1695	Transcriptional regulator
FPS98_RS18260	COG1126	abc transporter atp-binding protein
FPS98_RS18265	COG0765	amino acid transport
FPS98_RS18270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FPS98_RS18275	COG4912	Dna alkylation repair
FPS98_RS18290	COG0840	transmembrane signaling receptor activity
FPS98_RS18320	COG4682	membrane
FPS98_RS18325	COG2718	Belongs to the UPF0229 family
FPS98_RS18485	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FPS98_RS18495	COG5518	Phage portal protein
FPS98_RS18620	COG0305	Participates in initiation and elongation during chromosome replication
FPS98_RS18630	COG3935	DnaD domain protein
FPS98_RS18635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPS98_RS18725	COG0546	phosphoglycolate phosphatase activity
FPS98_RS18745	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FPS98_RS18750	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FPS98_RS18755	COG0328	RNA-DNA hybrid ribonuclease activity
FPS98_RS18760	COG3382	B3 4 domain protein
FPS98_RS18765	COG2233	PERMEase
FPS98_RS18860	COG3858	chitin binding
FPS98_RS18865	COG0735	belongs to the Fur family
FPS98_RS18870	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FPS98_RS18875	COG0702	epimerase
FPS98_RS18880	COG2096	Adenosyltransferase
FPS98_RS18885	COG2226	methyltransferase
FPS98_RS18890	COG1363	Peptidase, m42
FPS98_RS18895	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FPS98_RS18905	COG0546	phosphoglycolate phosphatase activity
FPS98_RS18910	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FPS98_RS18915	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FPS98_RS18920	COG2801	Transposase and inactivated derivatives
FPS98_RS18935	COG4555	ABC transporter
FPS98_RS18945	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FPS98_RS18950	COG2738	Putative neutral zinc metallopeptidase
FPS98_RS18955	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FPS98_RS18970	COG0655	NAD(P)H dehydrogenase (quinone) activity
FPS98_RS18985	COG1132	(ABC) transporter
FPS98_RS18990	COG3557	Belongs to the UPF0374 family
FPS98_RS18995	COG0456	acetyltransferase
FPS98_RS19000	COG1028	Short-chain dehydrogenase reductase Sdr
FPS98_RS19010	COG0840	transmembrane signaling receptor activity
FPS98_RS19020	COG0561	phosphatase activity
FPS98_RS19035	COG1988	membrane-bound metal-dependent
FPS98_RS19045	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FPS98_RS19050	COG1595	DNA-templated transcription, initiation
FPS98_RS19055	COG3384	dioxygenase
FPS98_RS19060	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FPS98_RS19070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FPS98_RS19075	COG2814	Major facilitator Superfamily
FPS98_RS19080	COG0583	DNA-binding transcription factor activity
FPS98_RS19100	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FPS98_RS19105	COG2197	response regulator
FPS98_RS19110	COG4585	Histidine kinase
FPS98_RS19115	COG4758	membrane
FPS98_RS19120	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FPS98_RS19125	COG1842	Phage shock protein A
FPS98_RS19140	COG0745	RESPONSE REGULATOR receiver
FPS98_RS19145	COG5002	protein histidine kinase activity
FPS98_RS19150	COG2124	cytochrome p450
FPS98_RS19155	COG1268	BioY protein
FPS98_RS19175	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FPS98_RS19215	COG1378	Sugar-specific transcriptional regulator TrmB
FPS98_RS19225	COG1136	(ABC) transporter
FPS98_RS19250	COG0745	RESPONSE REGULATOR receiver
FPS98_RS19260	COG2205	protein histidine kinase activity
FPS98_RS19300	COG2378	regulation of single-species biofilm formation
FPS98_RS19305	COG0673	inositol 2-dehydrogenase activity
FPS98_RS19310	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FPS98_RS19315	COG3842	ATPase activity
FPS98_RS19325	COG1840	ABC-type Fe3 transport system, periplasmic component
FPS98_RS19330	COG5002	protein histidine kinase activity
FPS98_RS19335	COG0745	RESPONSE REGULATOR receiver
FPS98_RS19340	COG2032	superoxide dismutase activity
FPS98_RS19345	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FPS98_RS19350	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FPS98_RS19360	COG0346	lactoylglutathione lyase activity
FPS98_RS19370	COG1278	Cold shock
FPS98_RS19375	COG3192	ethanolamine utilization protein
FPS98_RS19385	COG1742	UPF0060 membrane protein
FPS98_RS19395	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FPS98_RS19405	COG2205	protein histidine kinase activity
FPS98_RS19410	COG0745	RESPONSE REGULATOR receiver
FPS98_RS19440	COG0824	Thioesterase
FPS98_RS19455	COG0697	spore germination
FPS98_RS19460	COG1619	proteins homologs of microcin C7 resistance protein MccF
FPS98_RS19470	COG5002	protein histidine kinase activity
FPS98_RS19470	COG3850	Histidine kinase
FPS98_RS19475	COG0745	RESPONSE REGULATOR receiver
FPS98_RS19480	COG1114	Component of the transport system for branched-chain amino acids
FPS98_RS19485	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FPS98_RS19510	COG2133	pyrroloquinoline quinone binding
FPS98_RS19535	COG4191	Histidine kinase
FPS98_RS19540	COG2996	Protein conserved in bacteria
FPS98_RS19555	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FPS98_RS19560	COG0640	Transcriptional regulator
FPS98_RS19565	COG2814	Major facilitator Superfamily
FPS98_RS19585	COG0004	ammonium transporteR
FPS98_RS19600	COG1247	-acetyltransferase
FPS98_RS19615	COG0442	prolyl-tRNA aminoacylation
FPS98_RS19625	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FPS98_RS19630	COG0494	nUDIX hydrolase
FPS98_RS19645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FPS98_RS19655	COG0166	Belongs to the GPI family
FPS98_RS19660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FPS98_RS19665	COG1136	(ABC) transporter
FPS98_RS19670	COG0577	efflux transmembrane transporter activity
FPS98_RS19705	COG1253	flavin adenine dinucleotide binding
FPS98_RS19715	COG2076	Multidrug Resistance protein
FPS98_RS19720	COG2076	Multidrug Resistance protein
FPS98_RS19725	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FPS98_RS19735	COG1733	regulation of RNA biosynthetic process
FPS98_RS19740	COG1360	Flagellar Motor Protein
FPS98_RS19745	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FPS98_RS19755	COG0242	peptide deformylase activity
FPS98_RS19765	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FPS98_RS19770	COG0666	response to abiotic stimulus
FPS98_RS19780	COG0840	transmembrane signaling receptor activity
FPS98_RS19795	COG0697	spore germination
FPS98_RS19800	COG1346	cytolysis
FPS98_RS19825	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FPS98_RS19830	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FPS98_RS19835	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FPS98_RS19840	COG2258	MOSC domain
FPS98_RS19845	COG1187	pseudouridine synthase activity
FPS98_RS19850	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FPS98_RS19855	COG1278	Cold shock
FPS98_RS19865	COG2318	DinB family
FPS98_RS19885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FPS98_RS19890	COG0697	spore germination
FPS98_RS19910	COG1132	(ABC) transporter
FPS98_RS19915	COG1132	(ABC) transporter
FPS98_RS19920	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FPS98_RS19930	COG1288	antiporter activity
FPS98_RS19935	COG1473	amidohydrolase
FPS98_RS19950	COG3708	Transcriptional regulator
FPS98_RS19950	COG2207	Transcriptional regulator
FPS98_RS19955	COG1609	Transcriptional regulator
FPS98_RS19970	COG2226	methyltransferase
FPS98_RS19980	COG1473	amidohydrolase
FPS98_RS20000	COG0702	epimerase
FPS98_RS20015	COG4166	transmembrane transport
FPS98_RS20030	COG1823	symporter activity
FPS98_RS20045	COG2261	transglycosylase associated protein
FPS98_RS20050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FPS98_RS20055	COG5002	protein histidine kinase activity
FPS98_RS20060	COG0745	RESPONSE REGULATOR receiver
FPS98_RS20080	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FPS98_RS20085	COG3152	Membrane
FPS98_RS20095	COG0673	inositol 2-dehydrogenase activity
FPS98_RS20105	COG1940	carbohydrate kinase activity
FPS98_RS20110	COG4608	Belongs to the ABC transporter superfamily
FPS98_RS20115	COG0444	Belongs to the ABC transporter superfamily
FPS98_RS20125	COG0601	transmembrane transport
FPS98_RS20130	COG0747	negative chemotaxis
FPS98_RS20135	COG0673	inositol 2-dehydrogenase activity
FPS98_RS20160	COG2807	transmembrane transport
FPS98_RS20170	COG2197	response regulator
FPS98_RS20175	COG4585	Histidine kinase
FPS98_RS20180	COG3239	Fatty acid desaturase
FPS98_RS20185	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FPS98_RS20190	COG1917	Cupin 2, conserved barrel domain protein
FPS98_RS20190	COG4977	sequence-specific DNA binding
FPS98_RS20210	COG1136	(ABC) transporter
FPS98_RS20215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FPS98_RS20220	COG0726	polysaccharide deacetylase
FPS98_RS20240	COG4585	Histidine kinase
FPS98_RS20245	COG2197	response regulator
FPS98_RS20255	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FPS98_RS20265	COG0477	Major facilitator Superfamily
FPS98_RS20275	COG5002	protein histidine kinase activity
FPS98_RS20280	COG0745	RESPONSE REGULATOR receiver
FPS98_RS20285	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FPS98_RS20290	COG1086	Polysaccharide biosynthesis protein
FPS98_RS20305	COG1595	DNA-templated transcription, initiation
FPS98_RS20315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FPS98_RS20325	COG0745	RESPONSE REGULATOR receiver
FPS98_RS20325	COG2972	Histidine kinase
FPS98_RS20335	COG1511	domain protein
FPS98_RS20335	COG0842	Transport permease protein
FPS98_RS20340	COG1131	(ABC) transporter
FPS98_RS20350	COG2197	response regulator
FPS98_RS20360	COG1309	transcriptional regulator
FPS98_RS20365	COG2814	Major facilitator Superfamily
FPS98_RS20385	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FPS98_RS20395	COG0133	tryptophan synthase activity
FPS98_RS20420	COG1819	glycosyl
FPS98_RS20425	COG1442	glycosyl transferase family 8
FPS98_RS20450	COG3773	Cell wall hydrolase
FPS98_RS20530	COG0210	DNA helicase
FPS98_RS20555	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FPS98_RS20560	COG1597	lipid kinase activity
FPS98_RS20565	COG1940	carbohydrate kinase activity
FPS98_RS20570	COG0697	spore germination
FPS98_RS20575	COG1668	transmembrane transport
FPS98_RS20580	COG4555	ABC transporter
FPS98_RS20595	COG1595	DNA-templated transcription, initiation
FPS98_RS20610	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FPS98_RS20615	COG0154	amidase activity
FPS98_RS20620	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FPS98_RS20625	COG0688	phosphatidylethanolamine metabolic process
FPS98_RS20635	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FPS98_RS20640	COG1012	belongs to the aldehyde dehydrogenase family
FPS98_RS20655	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FPS98_RS20660	COG0210	DNA helicase
FPS98_RS20675	COG4211	Belongs to the binding-protein-dependent transport system permease family
FPS98_RS20695	COG2972	Histidine kinase
FPS98_RS20700	COG4753	response regulator
FPS98_RS20700	COG2207	Transcriptional regulator
FPS98_RS20715	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FPS98_RS20730	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
FPS98_RS20735	COG4496	protein, YerC YecD
FPS98_RS20740	COG1470	cell adhesion involved in biofilm formation
FPS98_RS20745	COG0745	RESPONSE REGULATOR receiver
FPS98_RS20750	COG2205	protein histidine kinase activity
FPS98_RS20750	COG2770	Histidine kinase
FPS98_RS20760	COG0516	GMP reductase activity
FPS98_RS20760	COG0517	IMP dehydrogenase activity
FPS98_RS20765	COG0667	Aldo Keto reductase
FPS98_RS20770	COG1191	sigma factor activity
FPS98_RS20880	COG3507	Belongs to the glycosyl hydrolase 43 family
FPS98_RS20915	COG2195	Cleaves the N-terminal amino acid of tripeptides
FPS98_RS20920	COG1177	transmembrane transport
FPS98_RS20925	COG1176	ABC-type spermidine putrescine transport system, permease component I
FPS98_RS20930	COG3842	ATPase activity
FPS98_RS20955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FPS98_RS20975	COG0559	Belongs to the binding-protein-dependent transport system permease family
FPS98_RS20985	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FPS98_RS21000	COG2814	Major facilitator Superfamily
FPS98_RS21015	COG0151	Belongs to the GarS family
FPS98_RS21030	COG3300	MHYT domain
FPS98_RS21030	COG5001	Diguanylate cyclase
FPS98_RS21040	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FPS98_RS21045	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FPS98_RS21050	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FPS98_RS21055	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FPS98_RS21060	COG0047	phosphoribosylformylglycinamidine synthase activity
FPS98_RS21065	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FPS98_RS21070	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FPS98_RS21075	COG1979	alcohol dehydrogenase
FPS98_RS21115	COG1876	peptidase activity
FPS98_RS21120	COG1181	Belongs to the D-alanine--D-alanine ligase family
FPS98_RS21130	COG2378	regulation of single-species biofilm formation
FPS98_RS21150	COG2304	oxidoreductase activity
FPS98_RS21180	COG2304	oxidoreductase activity
FPS98_RS21195	COG1459	type II secretion system
FPS98_RS21225	COG3279	Response regulator of the LytR AlgR family
FPS98_RS21280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FPS98_RS21285	COG2201	protein-glutamate methylesterase activity
FPS98_RS21295	COG1215	transferase activity, transferring glycosyl groups
FPS98_RS21300	COG5298	Protein conserved in bacteria
FPS98_RS21310	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FPS98_RS21315	COG2201	protein-glutamate methylesterase activity
FPS98_RS21350	COG0405	Gamma-glutamyltransferase
FPS98_RS21355	COG2059	Chromate
FPS98_RS21360	COG2059	Chromate
FPS98_RS21365	COG4608	Belongs to the ABC transporter superfamily
FPS98_RS21370	COG0444	Belongs to the ABC transporter superfamily
FPS98_RS21375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPS98_RS21385	COG0747	negative chemotaxis
FPS98_RS21395	COG0590	tRNA wobble adenosine to inosine editing
FPS98_RS21400	COG0577	efflux transmembrane transporter activity
FPS98_RS21405	COG1136	(ABC) transporter
FPS98_RS21410	COG2205	protein histidine kinase activity
FPS98_RS21415	COG0745	RESPONSE REGULATOR receiver
FPS98_RS21425	COG1595	DNA-templated transcription, initiation
FPS98_RS21440	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FPS98_RS21445	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FPS98_RS21450	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FPS98_RS21470	COG2252	PERMEase
FPS98_RS21485	COG1305	Transglutaminase-like
FPS98_RS21495	COG0714	Associated with various cellular activities
FPS98_RS21625	COG0546	phosphoglycolate phosphatase activity
FPS98_RS21635	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FPS98_RS21640	COG2340	Cysteine-rich secretory protein family
FPS98_RS21650	COG0805	protein transport
FPS98_RS21655	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FPS98_RS21665	COG0521	Mo-molybdopterin cofactor biosynthetic process
FPS98_RS21670	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FPS98_RS21675	COG0488	(ABC) transporter
FPS98_RS21690	COG0456	acetyltransferase
FPS98_RS21695	COG1214	PFAM Peptidase M22, glycoprotease
FPS98_RS21700	COG0802	atpase or kinase
FPS98_RS21705	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FPS98_RS21710	COG3091	SprT-like family
FPS98_RS21725	COG2183	response to ionizing radiation
FPS98_RS21730	COG1191	sigma factor activity
FPS98_RS21735	COG2172	sigma factor antagonist activity
FPS98_RS21740	COG1366	Belongs to the anti-sigma-factor antagonist family
FPS98_RS21745	COG2208	phosphoserine phosphatase activity
FPS98_RS21750	COG2172	sigma factor antagonist activity
FPS98_RS21755	COG2337	Toxic component of a toxin-antitoxin (TA) module
FPS98_RS21760	COG0864	Transcriptional regulator
FPS98_RS21765	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FPS98_RS21785	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FPS98_RS21790	COG0736	holo-[acyl-carrier-protein] synthase activity
FPS98_RS21805	COG0640	Transcriptional regulator
FPS98_RS21825	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FPS98_RS21830	COG1028	Short-chain dehydrogenase reductase Sdr
FPS98_RS21835	COG2249	NAD(P)H dehydrogenase (quinone) activity
FPS98_RS21845	COG1733	regulation of RNA biosynthetic process
FPS98_RS21850	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FPS98_RS21860	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FPS98_RS21865	COG0581	inorganic phosphate transmembrane transporter activity
FPS98_RS21870	COG0573	inorganic phosphate transmembrane transporter activity
FPS98_RS21875	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FPS98_RS21880	COG2155	Conserved Protein
FPS98_RS21895	COG0860	N-Acetylmuramoyl-L-alanine amidase
FPS98_RS21895	COG2247	cell wall binding repeat
FPS98_RS21915	COG4166	transmembrane transport
FPS98_RS21920	COG4166	transmembrane transport
FPS98_RS21925	COG4166	transmembrane transport
FPS98_RS21930	COG4166	transmembrane transport
FPS98_RS21945	COG4166	transmembrane transport
FPS98_RS21965	COG1316	TRANSCRIPTIONal
FPS98_RS21970	COG2814	Major facilitator Superfamily
FPS98_RS21980	COG1595	DNA-templated transcription, initiation
FPS98_RS21985	COG1028	Short-chain dehydrogenase reductase Sdr
FPS98_RS21995	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FPS98_RS22010	COG1999	signal sequence binding
FPS98_RS22015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FPS98_RS22035	COG0681	Belongs to the peptidase S26 family
FPS98_RS22065	COG0784	Response regulator, receiver
FPS98_RS22065	COG3437	response regulator, receiver
FPS98_RS22070	COG2197	response regulator
FPS98_RS22095	COG0714	Associated with various cellular activities
FPS98_RS22120	COG4555	ABC transporter
FPS98_RS22140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FPS98_RS22145	COG0477	Major facilitator Superfamily
FPS98_RS22150	COG1309	transcriptional regulator
FPS98_RS22155	COG1902	pentaerythritol trinitrate reductase activity
FPS98_RS22160	COG0372	Belongs to the citrate synthase family
FPS98_RS22165	COG2311	Membrane
FPS98_RS22170	COG0583	DNA-binding transcription factor activity
FPS98_RS22195	COG0840	transmembrane signaling receptor activity
FPS98_RS22195	COG5278	phosphoserine phosphatase activity
FPS98_RS22205	COG0740	serine-type endopeptidase activity
FPS98_RS22220	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FPS98_RS22225	COG1522	sequence-specific DNA binding
FPS98_RS22240	COG0475	glutathione-regulated potassium exporter activity
FPS98_RS22245	COG1929	Belongs to the glycerate kinase type-1 family
FPS98_RS22250	COG0438	transferase activity, transferring glycosyl groups
FPS98_RS22270	COG0523	cobalamin synthesis protein
FPS98_RS22295	COG0745	RESPONSE REGULATOR receiver
FPS98_RS22300	COG5002	protein histidine kinase activity
FPS98_RS22305	COG0778	Nitroreductase
FPS98_RS22310	COG1028	Short-chain dehydrogenase reductase Sdr
FPS98_RS22315	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FPS98_RS22320	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FPS98_RS22330	COG2197	response regulator
FPS98_RS22335	COG4585	Histidine kinase
FPS98_RS22355	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FPS98_RS22360	COG1971	Probably functions as a manganese efflux pump
FPS98_RS22365	COG3226	Transcriptional regulator
FPS98_RS22380	COG1595	DNA-templated transcription, initiation
FPS98_RS22395	COG2205	protein histidine kinase activity
FPS98_RS22405	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FPS98_RS22410	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FPS98_RS22420	COG3300	MHYT domain
FPS98_RS22420	COG5001	Diguanylate cyclase
FPS98_RS22425	COG0840	transmembrane signaling receptor activity
FPS98_RS22430	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FPS98_RS22455	COG4175	Glycine betaine
FPS98_RS22455	COG0517	IMP dehydrogenase activity
FPS98_RS22485	COG2217	Heavy metal translocating P-type atpase
FPS98_RS22495	COG2313	pseudouridylate synthase activity
FPS98_RS22500	COG1522	sequence-specific DNA binding
FPS98_RS22500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FPS98_RS22505	COG1846	Transcriptional regulator
FPS98_RS22510	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FPS98_RS22515	COG2259	Doxx family
FPS98_RS22520	COG1741	Belongs to the pirin family
FPS98_RS22525	COG1271	oxidase subunit
FPS98_RS22530	COG1294	oxidase, subunit
FPS98_RS22535	COG1522	sequence-specific DNA binding
FPS98_RS22540	COG2814	Major facilitator Superfamily
FPS98_RS22545	COG0427	acetyl-CoA hydrolase
FPS98_RS22555	COG3290	protein histidine kinase activity
FPS98_RS22555	COG3829	transcription factor binding
FPS98_RS22560	COG1288	antiporter activity
FPS98_RS22565	COG1473	amidohydrolase
FPS98_RS22570	COG4948	Mandelate Racemase Muconate Lactonizing
FPS98_RS22580	COG4841	protein insertion into membrane
FPS98_RS22585	COG5002	protein histidine kinase activity
FPS98_RS22590	COG0745	RESPONSE REGULATOR receiver
FPS98_RS22610	COG1028	Short-chain dehydrogenase reductase Sdr
FPS98_RS22615	COG2610	gluconate transmembrane transporter activity
FPS98_RS22620	COG3829	transcription factor binding
FPS98_RS22620	COG3290	protein histidine kinase activity
FPS98_RS22635	COG2819	hydrolase of the alpha beta superfamily
FPS98_RS22640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPS98_RS22645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPS98_RS22650	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FPS98_RS22655	COG2207	Transcriptional regulator
FPS98_RS22655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FPS98_RS22670	COG2318	DinB family
FPS98_RS22695	COG2801	Transposase and inactivated derivatives
FPS98_RS22715	COG5002	protein histidine kinase activity
FPS98_RS22715	COG3850	Histidine kinase
FPS98_RS22725	COG0400	carboxylic ester hydrolase activity
FPS98_RS22730	COG0346	lactoylglutathione lyase activity
FPS98_RS22735	COG0778	Nitroreductase
FPS98_RS22740	COG2318	DinB family
FPS98_RS22770	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FPS98_RS22780	COG2169	Transcriptional regulator
FPS98_RS22785	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FPS98_RS22790	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FPS98_RS22810	COG4978	Transcriptional regulator
FPS98_RS22810	COG0789	Transcriptional regulator
FPS98_RS22815	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FPS98_RS22835	COG1253	flavin adenine dinucleotide binding
FPS98_RS22840	COG0708	Exodeoxyribonuclease III
FPS98_RS22845	COG3173	Aminoglycoside phosphotransferase
FPS98_RS22860	COG2322	membrane
FPS98_RS22865	COG1113	amino acid transport
FPS98_RS22870	COG0657	acetylesterase activity
FPS98_RS22880	COG2814	Major facilitator Superfamily
FPS98_RS22885	COG1309	transcriptional regulator
FPS98_RS22900	COG1132	(ABC) transporter
FPS98_RS22910	COG2271	Major facilitator Superfamily
FPS98_RS22915	COG1136	(ABC) transporter
FPS98_RS22915	COG0577	efflux transmembrane transporter activity
FPS98_RS22920	COG0577	efflux transmembrane transporter activity
FPS98_RS22920	COG1136	(ABC) transporter
FPS98_RS22925	COG3850	Histidine kinase
FPS98_RS22925	COG5002	protein histidine kinase activity
FPS98_RS22950	COG5002	protein histidine kinase activity
FPS98_RS22955	COG0745	RESPONSE REGULATOR receiver
FPS98_RS22965	COG2801	Transposase and inactivated derivatives
FPS98_RS22970	COG1794	racemase activity, acting on amino acids and derivatives
FPS98_RS23070	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FPS98_RS23075	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FPS98_RS23085	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FPS98_RS23090	COG5662	AntiSigma factor
FPS98_RS23095	COG1595	DNA-templated transcription, initiation
FPS98_RS23105	COG0010	Belongs to the arginase family
FPS98_RS23195	COG0726	polysaccharide deacetylase
FPS98_RS23200	COG2194	sulfuric ester hydrolase activity
FPS98_RS23210	COG0489	protein tyrosine kinase activity
FPS98_RS23215	COG0860	N-Acetylmuramoyl-L-alanine amidase
FPS98_RS23220	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FPS98_RS23225	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FPS98_RS23230	COG0101	tRNA pseudouridine synthase activity
FPS98_RS23235	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FPS98_RS23240	COG1122	ATPase activity
FPS98_RS23245	COG1122	ATPase activity
FPS98_RS23250	COG0203	ribosomal protein L17
FPS98_RS23255	COG0202	RNA polymerase activity
FPS98_RS23260	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FPS98_RS23265	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FPS98_RS23270	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FPS98_RS23275	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FPS98_RS23280	COG0024	Methionine aminopeptidase
FPS98_RS23285	COG0563	adenylate kinase activity
FPS98_RS23290	COG0201	protein transport
FPS98_RS23295	COG0200	Binds to the 23S rRNA
FPS98_RS23300	COG1841	ribosomal large subunit assembly
FPS98_RS23305	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FPS98_RS23310	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FPS98_RS23315	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FPS98_RS23320	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FPS98_RS23325	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FPS98_RS23330	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FPS98_RS23335	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FPS98_RS23340	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FPS98_RS23345	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FPS98_RS23350	COG0255	Belongs to the universal ribosomal protein uL29 family
FPS98_RS23355	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FPS98_RS23360	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FPS98_RS23365	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FPS98_RS23370	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FPS98_RS23375	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FPS98_RS23380	COG0089	rRNA binding
FPS98_RS23385	COG0088	Forms part of the polypeptide exit tunnel
FPS98_RS23390	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FPS98_RS23395	COG0051	transcription antitermination factor activity, RNA binding
FPS98_RS23405	COG2346	COG2346, Truncated hemoglobins
FPS98_RS23410	COG0697	spore germination
FPS98_RS23415	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FPS98_RS23420	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FPS98_RS23425	COG0049	tRNA binding
FPS98_RS23430	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FPS98_RS23435	COG1358	cellular component organization or biogenesis
FPS98_RS23440	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FPS98_RS23445	COG0085	RNA polymerase activity
FPS98_RS23450	COG2813	Specifically methylates the guanine in position
FPS98_RS23455	COG0222	ribosome binding
FPS98_RS23465	COG0081	regulation of translation
FPS98_RS23470	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FPS98_RS23475	COG0250	Participates in transcription elongation, termination and antitermination
FPS98_RS23485	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FPS98_RS23495	COG3688	RNA-binding protein containing a PIN domain
FPS98_RS23500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FPS98_RS23505	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FPS98_RS23510	COG0215	cysteine-tRNA ligase activity
FPS98_RS23515	COG1045	serine acetyltransferase
FPS98_RS23520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FPS98_RS23525	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FPS98_RS23530	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FPS98_RS23535	COG4956	integral membrane protein (PIN domain superfamily)
FPS98_RS23545	COG1183	phosphatidylcholine synthase activity
FPS98_RS23550	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FPS98_RS23555	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FPS98_RS23560	COG0542	response to heat
FPS98_RS23565	COG3869	Catalyzes the specific phosphorylation of arginine residues in
FPS98_RS23570	COG3880	PFAM UvrB UvrC protein
FPS98_RS23580	COG0546	phosphoglycolate phosphatase activity
FPS98_RS23620	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FPS98_RS23625	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FPS98_RS23630	COG1396	sequence-specific DNA binding
FPS98_RS23635	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FPS98_RS23640	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FPS98_RS23645	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FPS98_RS23650	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FPS98_RS23655	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FPS98_RS23660	COG1785	Belongs to the alkaline phosphatase family
FPS98_RS23665	COG0512	Glutamine amidotransferase of anthranilate synthase
FPS98_RS23670	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FPS98_RS23675	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FPS98_RS23680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FPS98_RS23685	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FPS98_RS23690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FPS98_RS23695	COG4608	Belongs to the ABC transporter superfamily
FPS98_RS23700	COG0791	NLP P60 protein
FPS98_RS23705	COG4948	Mandelate Racemase Muconate Lactonizing
FPS98_RS23710	COG4166	transmembrane transport
FPS98_RS23715	COG0444	Belongs to the ABC transporter superfamily
FPS98_RS23720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPS98_RS23725	COG0601	transmembrane transport
FPS98_RS23835	COG2894	cell division
FPS98_RS23915	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FPS98_RS23925	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FPS98_RS23930	COG0735	belongs to the Fur family
FPS98_RS23935	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FPS98_RS23940	COG1121	(ABC) transporter
FPS98_RS23955	COG1695	Transcriptional regulator
FPS98_RS23960	COG0772	Belongs to the SEDS family
FPS98_RS23970	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FPS98_RS23975	COG0561	phosphatase activity
FPS98_RS23980	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FPS98_RS23985	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FPS98_RS23995	COG3610	response to peptide
FPS98_RS24005	COG0515	serine threonine protein kinase
FPS98_RS24010	COG2304	oxidoreductase activity
FPS98_RS24015	COG2208	phosphoserine phosphatase activity
FPS98_RS24020	COG1098	S1 RNA binding domain
FPS98_RS24045	COG4533	DNA binding
FPS98_RS24060	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FPS98_RS24065	COG3956	TIGRFAM MazG family protein
FPS98_RS24070	COG2244	polysaccharide biosynthetic process
FPS98_RS24075	COG2002	toxin-antitoxin pair type II binding
FPS98_RS24080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FPS98_RS24085	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FPS98_RS24095	COG0193	aminoacyl-tRNA hydrolase activity
FPS98_RS24100	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FPS98_RS24105	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FPS98_RS24110	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FPS98_RS24115	COG0523	cobalamin synthesis protein
FPS98_RS24120	COG2088	sporulation resulting in formation of a cellular spore
FPS98_RS24125	COG0251	oxidation-reduction process
FPS98_RS24130	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FPS98_RS24135	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FPS98_RS24145	COG4466	Protein conserved in bacteria
FPS98_RS24150	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FPS98_RS24160	COG1388	LysM domain
FPS98_RS24160	COG3584	3D domain protein
FPS98_RS24165	COG0084	hydrolase, TatD family'
FPS98_RS24170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FPS98_RS24170	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FPS98_RS24175	COG2002	toxin-antitoxin pair type II binding
FPS98_RS24180	COG2226	methyltransferase
FPS98_RS24185	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FPS98_RS24190	COG2827	Endonuclease containing a URI domain
FPS98_RS24195	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FPS98_RS24200	COG4467	Involved in initiation control of chromosome replication
FPS98_RS24205	COG1774	PSP1 C-terminal conserved region
FPS98_RS24210	COG0470	DNA polymerase III
FPS98_RS24215	COG1728	Protein conserved in bacteria
FPS98_RS24220	COG3870	Protein conserved in bacteria
FPS98_RS24225	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FPS98_RS24230	COG1982	Orn Lys Arg decarboxylase major
FPS98_RS24270	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FPS98_RS24275	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FPS98_RS24280	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FPS98_RS24285	COG3852	Histidine kinase
FPS98_RS24295	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FPS98_RS24295	COG2199	diguanylate cyclase activity
FPS98_RS24305	COG0586	Pfam SNARE associated Golgi protein
FPS98_RS24320	COG2910	NAD(P)H-binding
FPS98_RS24330	COG1937	Protein conserved in bacteria
FPS98_RS24340	COG2210	Belongs to the sulfur carrier protein TusA family
FPS98_RS24345	COG0730	response to heat
FPS98_RS24350	COG0425	Belongs to the sulfur carrier protein TusA family
FPS98_RS24355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FPS98_RS24355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPS98_RS24360	COG0425	Belongs to the sulfur carrier protein TusA family
FPS98_RS24360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FPS98_RS24370	COG0768	penicillin binding
FPS98_RS24375	COG1595	DNA-templated transcription, initiation
FPS98_RS24385	COG1187	pseudouridine synthase activity
FPS98_RS24390	COG0590	tRNA wobble adenosine to inosine editing
FPS98_RS24400	COG3711	transcriptional antiterminator
FPS98_RS24405	COG2190	(PTS) system
FPS98_RS24415	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FPS98_RS24420	COG2190	(PTS) system
FPS98_RS24420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FPS98_RS24420	COG1263	PTS System
FPS98_RS24440	COG1733	regulation of RNA biosynthetic process
FPS98_RS24445	COG2259	Doxx family
FPS98_RS24455	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FPS98_RS24490	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FPS98_RS24495	COG1349	DNA-binding transcription factor activity
FPS98_RS24500	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FPS98_RS24505	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FPS98_RS24525	COG2224	Isocitrate lyase
FPS98_RS24530	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FPS98_RS24540	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FPS98_RS24545	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FPS98_RS24550	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FPS98_RS24560	COG0517	IMP dehydrogenase activity
FPS98_RS24560	COG0516	GMP reductase activity
FPS98_RS24590	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FPS98_RS24595	COG0745	RESPONSE REGULATOR receiver
FPS98_RS24600	COG5002	protein histidine kinase activity
FPS98_RS24600	COG3850	Histidine kinase
FPS98_RS24740	COG0187	DNA topoisomerase II activity
FPS98_RS24750	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FPS98_RS24755	COG2501	S4 domain
FPS98_RS24760	COG0592	DNA-directed DNA polymerase activity
FPS98_RS24765	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FPS98_RS24770	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FPS98_RS24780	COG0594	ribonuclease P activity
FPS98_RS24785	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FPS98_RS24790	COG0706	membrane insertase activity
FPS98_RS24795	COG1847	R3H domain protein
FPS98_RS24800	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FPS98_RS24805	COG0445	tRNA wobble uridine modification
FPS98_RS24810	COG0357	Ribosomal RNA small subunit methyltransferase G
FPS98_RS24825	COG1475	DNA binding
FPS98_RS24830	COG1192	Involved in chromosome partitioning
FPS98_RS24835	COG1475	DNA binding
FPS98_RS24840	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FPS98_RS24850	COG1597	lipid kinase activity
FPS98_RS24865	COG0668	transmembrane transport
FPS98_RS24870	COG4481	Protein conserved in bacteria
FPS98_RS24885	COG1164	Oligoendopeptidase f
FPS98_RS24890	COG0702	epimerase
FPS98_RS24895	COG0012	GTP binding
FPS98_RS24900	COG0360	Binds together with S18 to 16S ribosomal RNA
FPS98_RS24905	COG0629	single-stranded DNA binding
FPS98_RS24910	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FPS98_RS24920	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FPS98_RS24925	COG0359	binds to the 23S rRNA
FPS98_RS24930	COG0305	Participates in initiation and elongation during chromosome replication
FPS98_RS24935	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FPS98_RS24950	COG0741	lytic transglycosylase activity
FPS98_RS24950	COG1196	nuclear chromosome segregation
FPS98_RS24950	COG0739	heme binding
FPS98_RS24955	COG0745	RESPONSE REGULATOR receiver
FPS98_RS24960	COG5002	protein histidine kinase activity
FPS98_RS24970	COG4853	Protein conserved in bacteria
FPS98_RS24975	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FPS98_RS24985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FPS98_RS25000	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FPS98_RS25005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FPS98_RS25005	COG2207	Transcriptional regulator
FPS98_RS25010	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FPS98_RS25015	COG0662	Cupin 2, conserved barrel domain protein
FPS98_RS25025	COG2814	Major facilitator Superfamily
FPS98_RS25030	COG0640	Transcriptional regulator
FPS98_RS25035	COG2378	regulation of single-species biofilm formation
FPS98_RS25095	COG0277	FAD linked oxidase domain protein
FPS98_RS25105	COG0745	RESPONSE REGULATOR receiver
FPS98_RS25105	COG2972	Histidine kinase
FPS98_RS25110	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FPS98_RS25115	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FPS98_RS25135	COG0579	oxidoreductase
FPS98_RS25140	COG1192	Involved in chromosome partitioning
FPS98_RS25150	COG1404	Belongs to the peptidase S8 family
FPS98_RS25175	COG1595	DNA-templated transcription, initiation
FPS98_RS25185	COG2169	Transcriptional regulator
FPS98_RS25185	COG1917	Cupin 2, conserved barrel domain protein
FPS98_RS25200	COG2214	Heat shock protein DnaJ domain protein
FPS98_RS25205	COG0431	NADPH-dependent FMN reductase
FPS98_RS25215	COG0346	lactoylglutathione lyase activity
FPS98_RS25245	COG0693	protein deglycase activity
FPS98_RS25250	COG0583	DNA-binding transcription factor activity
FPS98_RS25255	COG1349	DNA-binding transcription factor activity
FPS98_RS25265	COG2222	sugar isomerase
FPS98_RS25275	COG1940	carbohydrate kinase activity
FPS98_RS25280	COG3250	beta-galactosidase activity
FPS98_RS25285	COG2972	Histidine kinase
FPS98_RS25290	COG4753	response regulator
FPS98_RS25290	COG2207	Transcriptional regulator
FPS98_RS25295	COG2182	Extracellular solute-binding protein
FPS98_RS25300	COG1175	transmembrane transport
FPS98_RS25305	COG0395	ABC-type sugar transport system, permease component
FPS98_RS25310	COG5578	integral membrane protein
FPS98_RS25325	COG1649	PFAM Uncharacterised BCR, COG1649
FPS98_RS25325	COG0726	polysaccharide deacetylase
FPS98_RS25340	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FPS98_RS25355	COG1126	abc transporter atp-binding protein
FPS98_RS25360	COG0765	amino acid transport
FPS98_RS25365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FPS98_RS25385	COG1136	(ABC) transporter
FPS98_RS25390	COG0577	efflux transmembrane transporter activity
FPS98_RS25405	COG2197	response regulator
FPS98_RS25410	COG2824	Alkylphosphonate utilization operon protein PhnA
FPS98_RS25420	COG0457	Tetratricopeptide repeat
FPS98_RS25420	COG0463	Glycosyl transferase, family 2
FPS98_RS25470	COG0463	Glycosyl transferase, family 2
FPS98_RS25470	COG0457	Tetratricopeptide repeat
FPS98_RS25475	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FPS98_RS25480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPS98_RS25485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPS98_RS25495	COG1840	ABC-type Fe3 transport system, periplasmic component
FPS98_RS25500	COG3842	ATPase activity
FPS98_RS25515	COG2076	Multidrug Resistance protein
FPS98_RS25535	COG1846	Transcriptional regulator
FPS98_RS25545	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FPS98_RS25550	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FPS98_RS25555	COG1028	Short-chain dehydrogenase reductase Sdr
FPS98_RS25560	COG3829	transcription factor binding
FPS98_RS25565	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FPS98_RS25570	COG0739	heme binding
FPS98_RS25590	COG2204	response regulator
FPS98_RS25595	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FPS98_RS25600	COG1012	belongs to the aldehyde dehydrogenase family
FPS98_RS25605	COG0726	polysaccharide deacetylase
FPS98_RS25635	COG1968	undecaprenyl-diphosphatase activity
FPS98_RS25650	COG1595	DNA-templated transcription, initiation
FPS98_RS25665	COG2076	Multidrug Resistance protein
FPS98_RS25670	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FPS98_RS25675	COG0672	)-iron permease
FPS98_RS25680	COG2837	iron assimilation
FPS98_RS25685	COG2822	iron ion transport
FPS98_RS25695	COG0584	glycerophosphoryl diester phosphodiesterase
FPS98_RS25700	COG3842	ATPase activity
FPS98_RS25710	COG1175	transmembrane transport
FPS98_RS25715	COG0395	ABC-type sugar transport system, permease component
FPS98_RS25725	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FPS98_RS25730	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FPS98_RS25760	COG1649	PFAM Uncharacterised BCR, COG1649
FPS98_RS25785	COG1280	lysine exporter protein (LysE YggA)
FPS98_RS25835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPS98_RS25850	COG2201	protein-glutamate methylesterase activity
FPS98_RS25865	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPS98_RS25870	COG4605	iron ion homeostasis
FPS98_RS25875	COG4604	ABC transporter, ATP-binding protein
FPS98_RS25880	COG4607	ABC-type enterochelin transport system periplasmic component
FPS98_RS25890	COG1120	ATPase activity
FPS98_RS25905	COG2011	ABC-type metal ion transport system permease component
FPS98_RS25935	COG1176	ABC-type spermidine putrescine transport system, permease component I
FPS98_RS25945	COG3842	ATPase activity
FPS98_RS25950	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FPS98_RS25955	COG3397	chitin binding
FPS98_RS25960	COG0534	Mate efflux family protein
FPS98_RS25965	COG1285	pathogenesis
FPS98_RS26010	COG0514	ATP-dependent DNA helicase (RecQ)
FPS98_RS26040	COG4191	Histidine kinase
FPS98_RS26040	COG0745	RESPONSE REGULATOR receiver
FPS98_RS26040	COG2205	protein histidine kinase activity
FPS98_RS26045	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FPS98_RS26045	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FPS98_RS26060	COG3394	polysaccharide catabolic process
FPS98_RS26065	COG1447	Phosphotransferase system cellobiose-specific component IIA
FPS98_RS26070	COG1486	melibiose metabolic process
FPS98_RS26075	COG0561	phosphatase activity
FPS98_RS26080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FPS98_RS26085	COG2205	protein histidine kinase activity
FPS98_RS26105	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FPS98_RS26120	COG1012	belongs to the aldehyde dehydrogenase family
FPS98_RS26125	COG3284	Transcriptional regulator
FPS98_RS26130	COG0473	3-isopropylmalate dehydrogenase activity
FPS98_RS26135	COG1012	belongs to the aldehyde dehydrogenase family
FPS98_RS26145	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FPS98_RS26150	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FPS98_RS26155	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FPS98_RS26155	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FPS98_RS26160	COG0277	FAD linked oxidase domain protein
FPS98_RS26165	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FPS98_RS26170	COG0840	transmembrane signaling receptor activity
FPS98_RS26180	COG0513	Belongs to the DEAD box helicase family
FPS98_RS26195	COG3711	transcriptional antiterminator
FPS98_RS26200	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FPS98_RS26205	COG0246	Mannitol dehydrogenase
FPS98_RS26220	COG3119	arylsulfatase activity
FPS98_RS26235	COG5002	protein histidine kinase activity
FPS98_RS26240	COG0745	RESPONSE REGULATOR receiver
FPS98_RS26265	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FPS98_RS26270	COG1012	belongs to the aldehyde dehydrogenase family
FPS98_RS26270	COG1454	alcohol dehydrogenase
FPS98_RS26280	COG4869	propanediol catabolic process
FPS98_RS26290	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
FPS98_RS26300	COG1160	GTP binding
FPS98_RS26320	COG4303	Ethanolamine ammonia lyase large subunit
FPS98_RS26325	COG4302	ethanolamine ammonia-lyase activity
FPS98_RS26330	COG0039	L-malate dehydrogenase activity
FPS98_RS26395	COG2309	aminopeptidase activity
FPS98_RS26410	COG2233	PERMEase
FPS98_RS26420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FPS98_RS26425	COG2207	Transcriptional regulator
FPS98_RS26430	COG1765	OsmC-like protein
FPS98_RS26435	COG4187	Peptidase family M20/M25/M40
FPS98_RS26440	COG1414	Transcriptional regulator
FPS98_RS26450	COG0833	amino acid
FPS98_RS26470	COG1846	Transcriptional regulator
FPS98_RS26480	COG0840	transmembrane signaling receptor activity
FPS98_RS26490	COG3845	ABC transporter
FPS98_RS26495	COG4603	Belongs to the binding-protein-dependent transport system permease family
FPS98_RS26500	COG1079	Belongs to the binding-protein-dependent transport system permease family
FPS98_RS26505	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FPS98_RS26510	COG0813	purine-nucleoside phosphorylase activity
FPS98_RS26520	COG0659	secondary active sulfate transmembrane transporter activity
FPS98_RS26530	COG0546	phosphoglycolate phosphatase activity
FPS98_RS26535	COG3842	ATPase activity
FPS98_RS26540	COG1175	transmembrane transport
FPS98_RS26545	COG0395	ABC-type sugar transport system, permease component
FPS98_RS26550	COG1653	transport
FPS98_RS26555	COG0584	glycerophosphoryl diester phosphodiesterase
FPS98_RS26565	COG0405	Gamma-glutamyltransferase
FPS98_RS26575	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FPS98_RS26580	COG0531	amino acid
FPS98_RS26590	COG2807	transmembrane transport
FPS98_RS26595	COG2186	Transcriptional regulator
FPS98_RS26615	COG1122	ATPase activity
FPS98_RS26620	COG1122	ATPase activity
FPS98_RS26630	COG0596	Alpha beta hydrolase
FPS98_RS26650	COG0626	cystathionine gamma-synthase activity
FPS98_RS26655	COG2204	response regulator
FPS98_RS26660	COG2329	Antibiotic biosynthesis monooxygenase
FPS98_RS26675	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FPS98_RS26695	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FPS98_RS26700	COG0116	Belongs to the methyltransferase superfamily
FPS98_RS26725	COG0564	pseudouridine synthase activity
FPS98_RS26735	COG0789	Transcriptional regulator
FPS98_RS26740	COG1664	Polymer-forming cytoskeletal
FPS98_RS26745	COG1309	transcriptional regulator
FPS98_RS26765	COG1078	dGTPase activity
FPS98_RS26770	COG3465	dGTPase activity
FPS98_RS26810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FPS98_RS26815	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FPS98_RS26820	COG0010	Belongs to the arginase family
FPS98_RS26840	COG3829	transcription factor binding
FPS98_RS26845	COG1509	lysine 2,3-aminomutase activity
FPS98_RS26850	COG0247	lactate metabolic process
FPS98_RS26850	COG2181	nitrate reductase activity
FPS98_RS26855	COG1595	DNA-templated transcription, initiation
FPS98_RS26865	COG0183	Belongs to the thiolase family
FPS98_RS26870	COG1250	3-hydroxyacyl-CoA dehydrogenase
FPS98_RS26875	COG1960	acyl-CoA dehydrogenase activity
FPS98_RS26880	COG1960	acyl-CoA dehydrogenase activity
FPS98_RS26885	COG1309	transcriptional regulator
FPS98_RS26890	COG1703	isobutyryl-CoA mutase activity
FPS98_RS26890	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FPS98_RS26890	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FPS98_RS26915	COG3343	RNA polymerase activity
FPS98_RS26920	COG0504	CTP synthase activity
FPS98_RS26930	COG2204	response regulator
FPS98_RS26935	COG0191	fructose-bisphosphate aldolase activity
FPS98_RS26940	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FPS98_RS26945	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FPS98_RS26950	COG1494	fructose-1,6-bisphosphatase
FPS98_RS26955	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FPS98_RS26960	COG0739	heme binding
FPS98_RS26970	COG0254	rRNA binding
FPS98_RS26975	COG0415	Belongs to the DNA photolyase family
FPS98_RS26980	COG1435	thymidine kinase activity
FPS98_RS26990	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FPS98_RS26995	COG2890	protein-(glutamine-N5) methyltransferase activity
FPS98_RS27010	COG0009	L-threonylcarbamoyladenylate synthase
FPS98_RS27015	COG1971	Probably functions as a manganese efflux pump
FPS98_RS27025	COG0698	ribose 5-phosphate isomerase
FPS98_RS27030	COG4475	Protein of unknown function (DUF436)
FPS98_RS27040	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FPS98_RS27045	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FPS98_RS27050	COG1361	Conserved repeat domain
FPS98_RS27055	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FPS98_RS27060	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FPS98_RS27065	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FPS98_RS27070	COG0156	8-amino-7-oxononanoate synthase activity
FPS98_RS27075	COG0596	Alpha beta hydrolase
FPS98_RS27080	COG4106	trans-aconitate 2-methyltransferase activity
FPS98_RS27085	COG2207	Transcriptional regulator
FPS98_RS27085	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FPS98_RS27090	COG0183	Belongs to the thiolase family
FPS98_RS27105	COG0356	it plays a direct role in the translocation of protons across the membrane
FPS98_RS27115	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FPS98_RS27120	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FPS98_RS27125	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FPS98_RS27130	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FPS98_RS27135	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FPS98_RS27140	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FPS98_RS27150	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FPS98_RS27155	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FPS98_RS27160	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FPS98_RS27165	COG0649	NAD binding
FPS98_RS27170	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FPS98_RS27175	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FPS98_RS27185	COG0713	ATP synthesis coupled electron transport
FPS98_RS27190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FPS98_RS27195	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FPS98_RS27200	COG1007	ATP synthesis coupled electron transport
FPS98_RS27215	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FPS98_RS27220	COG2385	sporulation resulting in formation of a cellular spore
FPS98_RS27225	COG0739	heme binding
FPS98_RS27230	COG1609	Transcriptional regulator
FPS98_RS27240	COG4786	Flagellar basal body rod
FPS98_RS27260	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FPS98_RS27265	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FPS98_RS27270	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FPS98_RS27280	COG1739	Uncharacterized protein family UPF0029
FPS98_RS27290	COG2373	Large extracellular alpha-helical protein
FPS98_RS27295	COG0544	peptidyl-prolyl cis-trans isomerase activity
FPS98_RS27325	COG1404	Belongs to the peptidase S8 family
FPS98_RS27330	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FPS98_RS27335	COG0726	polysaccharide deacetylase
FPS98_RS27335	COG1649	PFAM Uncharacterised BCR, COG1649
FPS98_RS27345	COG2197	response regulator
FPS98_RS27355	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FPS98_RS27380	COG4786	Flagellar basal body rod
FPS98_RS27380	COG1256	bacterial-type flagellum assembly
FPS98_RS27385	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FPS98_RS27395	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
FPS98_RS27400	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FPS98_RS27405	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FPS98_RS27410	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FPS98_RS27420	COG1334	flagellar protein FlaG
FPS98_RS27425	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FPS98_RS27430	COG1516	flagellar protein fliS
FPS98_RS27460	COG0765	amino acid transport
FPS98_RS27470	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FPS98_RS27475	COG0653	protein targeting
FPS98_RS27490	COG5002	protein histidine kinase activity
FPS98_RS27505	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FPS98_RS27510	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FPS98_RS27515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FPS98_RS27520	COG0505	Belongs to the CarA family
FPS98_RS27530	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FPS98_RS27540	COG2199	diguanylate cyclase activity
FPS98_RS27540	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FPS98_RS27550	COG0137	argininosuccinate synthase activity
FPS98_RS27555	COG0165	Argininosuccinate lyase
FPS98_RS27565	COG0531	amino acid
FPS98_RS27575	COG1979	alcohol dehydrogenase
FPS98_RS27580	COG2884	Cell division ATP-binding protein ftsE
FPS98_RS27585	COG2177	Part of the ABC transporter FtsEX involved in
FPS98_RS27590	COG0739	heme binding
FPS98_RS27595	COG0793	Belongs to the peptidase S41A family
FPS98_RS27595	COG3409	Peptidoglycan-binding domain 1 protein
FPS98_RS27615	COG0556	nucleotide-excision repair
FPS98_RS27620	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FPS98_RS27625	COG1418	mRNA catabolic process
FPS98_RS27630	COG1950	PFAM Membrane protein of
FPS98_RS27635	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FPS98_RS27640	COG0110	maltose O-acetyltransferase activity
FPS98_RS27645	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FPS98_RS27650	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FPS98_RS27655	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FPS98_RS27660	COG0131	Imidazoleglycerol-phosphate dehydratase
FPS98_RS27665	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FPS98_RS27670	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FPS98_RS27675	COG0107	imidazoleglycerol-phosphate synthase activity
FPS98_RS27680	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FPS98_RS27680	COG0140	phosphoribosyl-ATP diphosphatase activity
FPS98_RS27685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FPS98_RS27730	COG0492	ferredoxin-NADP+ reductase activity
FPS98_RS27735	COG1660	Displays ATPase and GTPase activities
FPS98_RS27740	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FPS98_RS27745	COG1481	regulation of sporulation
FPS98_RS27750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FPS98_RS27790	COG4191	Histidine kinase
FPS98_RS27795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FPS98_RS27800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPS98_RS27805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPS98_RS27825	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FPS98_RS27840	COG1757	Na H antiporter
FPS98_RS27845	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FPS98_RS27850	COG0126	phosphoglycerate kinase activity
FPS98_RS27855	COG0149	triose-phosphate isomerase activity
FPS98_RS27865	COG0148	phosphopyruvate hydratase activity
FPS98_RS27870	COG1120	ATPase activity
FPS98_RS27875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPS98_RS27880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPS98_RS27885	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FPS98_RS27900	COG0390	transport system, permease component
FPS98_RS27905	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FPS98_RS27915	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FPS98_RS27920	COG0557	exoribonuclease II activity
FPS98_RS27925	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FPS98_RS27935	COG0653	protein targeting
FPS98_RS27950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPS98_RS27955	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FPS98_RS27955	COG2070	2-Nitropropane dioxygenase
FPS98_RS27960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FPS98_RS27960	COG3321	synthase
FPS98_RS27960	COG1028	Short-chain dehydrogenase reductase Sdr
FPS98_RS27960	COG4221	oxidoreductase activity
FPS98_RS27965	COG4221	oxidoreductase activity
FPS98_RS27965	COG3321	synthase
FPS98_RS27965	COG1028	Short-chain dehydrogenase reductase Sdr
FPS98_RS27965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FPS98_RS27970	COG3321	synthase
FPS98_RS27970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FPS98_RS27970	COG4221	oxidoreductase activity
FPS98_RS27970	COG0300	oxidoreductase activity
FPS98_RS27975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FPS98_RS27975	COG1028	Short-chain dehydrogenase reductase Sdr
FPS98_RS27975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FPS98_RS27975	COG3321	synthase
FPS98_RS27975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FPS98_RS27980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FPS98_RS27980	COG3321	synthase
FPS98_RS27980	COG4221	oxidoreductase activity
FPS98_RS27980	COG1028	Short-chain dehydrogenase reductase Sdr
FPS98_RS27985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FPS98_RS27985	COG1028	Short-chain dehydrogenase reductase Sdr
FPS98_RS27985	COG4221	oxidoreductase activity
FPS98_RS27985	COG3321	synthase
FPS98_RS27990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FPS98_RS27995	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FPS98_RS28000	COG3425	synthase
FPS98_RS28005	COG1024	Enoyl-CoA hydratase
FPS98_RS28010	COG1024	Enoyl-CoA hydratase
FPS98_RS28015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FPS98_RS28015	COG3321	synthase
FPS98_RS28015	COG4221	oxidoreductase activity
FPS98_RS28015	COG1028	Short-chain dehydrogenase reductase Sdr
FPS98_RS28020	COG0300	oxidoreductase activity
FPS98_RS28020	COG3321	synthase
FPS98_RS28020	COG4221	oxidoreductase activity
FPS98_RS28020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FPS98_RS28025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FPS98_RS28025	COG1028	Short-chain dehydrogenase reductase Sdr
FPS98_RS28025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FPS98_RS28025	COG3321	synthase
FPS98_RS28025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FPS98_RS28045	COG1114	Component of the transport system for branched-chain amino acids
FPS98_RS28065	COG3706	GGDEF domain
FPS98_RS28090	COG0745	RESPONSE REGULATOR receiver
FPS98_RS28095	COG5002	protein histidine kinase activity
FPS98_RS28105	COG0544	peptidyl-prolyl cis-trans isomerase activity
FPS98_RS28120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FPS98_RS28140	COG0165	Argininosuccinate lyase
FPS98_RS28145	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FPS98_RS28165	COG0601	transmembrane transport
FPS98_RS28170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPS98_RS28175	COG0444	Belongs to the ABC transporter superfamily
FPS98_RS28180	COG4608	Belongs to the ABC transporter superfamily
FPS98_RS28205	COG0477	Major facilitator Superfamily
FPS98_RS28210	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FPS98_RS28215	COG1982	Orn Lys Arg decarboxylase major
FPS98_RS28220	COG2313	pseudouridylate synthase activity
FPS98_RS28235	COG0697	spore germination
FPS98_RS28240	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FPS98_RS28245	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FPS98_RS28255	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FPS98_RS28260	COG0109	protoheme IX farnesyltransferase activity
FPS98_RS28270	COG1999	signal sequence binding
FPS98_RS28280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FPS98_RS28305	COG0778	Nitroreductase
FPS98_RS28310	COG1733	regulation of RNA biosynthetic process
FPS98_RS28365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FPS98_RS28370	COG0601	transmembrane transport
FPS98_RS28375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPS98_RS28380	COG0444	Belongs to the ABC transporter superfamily
FPS98_RS28385	COG4608	Belongs to the ABC transporter superfamily
FPS98_RS28405	COG0747	negative chemotaxis
FPS98_RS28410	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FPS98_RS28465	COG4166	transmembrane transport
FPS98_RS28475	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FPS98_RS28495	COG5492	domain, Protein
FPS98_RS28505	COG1252	NADH dehydrogenase
FPS98_RS28525	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FPS98_RS28530	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FPS98_RS28535	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FPS98_RS28535	COG1918	ferrous iron import across plasma membrane
FPS98_RS28545	COG1414	Transcriptional regulator
FPS98_RS28550	COG2801	Transposase and inactivated derivatives
FPS98_RS28565	COG1595	DNA-templated transcription, initiation
FPS98_RS28575	COG2323	membrane
FPS98_RS28580	COG3852	Histidine kinase
FPS98_RS28590	COG1129	ABC transporter
FPS98_RS28595	COG4214	carbohydrate transport
FPS98_RS28600	COG1929	Belongs to the glycerate kinase type-1 family
FPS98_RS28610	COG0745	RESPONSE REGULATOR receiver
FPS98_RS28615	COG3850	Histidine kinase
FPS98_RS28615	COG5002	protein histidine kinase activity
FPS98_RS28640	COG0024	Methionine aminopeptidase
FPS98_RS28645	COG0519	Catalyzes the synthesis of GMP from XMP
FPS98_RS28765	COG5632	N-Acetylmuramoyl-L-alanine amidase
FPS98_RS28765	COG3409	Peptidoglycan-binding domain 1 protein
FPS98_RS28785	COG0457	Tetratricopeptide repeat
FPS98_RS28785	COG0463	Glycosyl transferase, family 2
FPS98_RS28790	COG0463	Glycosyl transferase, family 2
FPS98_RS28790	COG0457	Tetratricopeptide repeat
FPS98_RS28800	COG5002	protein histidine kinase activity
FPS98_RS28820	COG5002	protein histidine kinase activity
FPS98_RS28825	COG0745	RESPONSE REGULATOR receiver
FPS98_RS28840	COG4895	conserved protein (DUF2196)
FPS98_RS28855	COG1510	regulation of RNA biosynthetic process
FPS98_RS28860	COG0517	IMP dehydrogenase activity
FPS98_RS28860	COG4175	Glycine betaine
FPS98_RS28870	COG2113	Glycine betaine
FPS98_RS28880	COG0154	amidase activity
FPS98_RS28885	COG2207	Transcriptional regulator
FPS98_RS28890	COG0586	Pfam SNARE associated Golgi protein
FPS98_RS28895	COG2304	oxidoreductase activity
FPS98_RS28930	COG2814	Major facilitator Superfamily
FPS98_RS28935	COG2140	Oxalate decarboxylase
FPS98_RS28950	COG3226	Transcriptional regulator
FPS98_RS28955	COG3842	ATPase activity
FPS98_RS28965	COG1175	transmembrane transport
FPS98_RS28980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FPS98_RS28990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FPS98_RS29015	COG1111	helicase
FPS98_RS29015	COG1205	dead DEAH box helicase
FPS98_RS29020	COG3359	exonuclease
FPS98_RS29030	COG0596	Alpha beta hydrolase
FPS98_RS29080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FPS98_RS29085	COG1309	transcriptional regulator
FPS98_RS29090	COG2076	Multidrug Resistance protein
FPS98_RS29100	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FPS98_RS29105	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FPS98_RS29110	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FPS98_RS29115	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FPS98_RS29135	COG1131	(ABC) transporter
FPS98_RS29150	COG0714	Associated with various cellular activities
FPS98_RS29180	COG0840	transmembrane signaling receptor activity
FPS98_RS29190	COG1131	(ABC) transporter
FPS98_RS29200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FPS98_RS29205	COG0697	spore germination
FPS98_RS29225	COG1028	Short-chain dehydrogenase reductase Sdr
FPS98_RS29230	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FPS98_RS29230	COG2010	Cytochrome c
FPS98_RS29245	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FPS98_RS29260	COG2050	protein possibly involved in aromatic compounds catabolism
FPS98_RS29265	COG2050	protein possibly involved in aromatic compounds catabolism
FPS98_RS29270	COG1024	Enoyl-CoA hydratase
FPS98_RS29275	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FPS98_RS29285	COG1024	Enoyl-CoA hydratase
FPS98_RS29290	COG1250	3-hydroxyacyl-CoA dehydrogenase
FPS98_RS29295	COG1250	3-hydroxyacyl-CoA dehydrogenase
FPS98_RS29300	COG0183	Belongs to the thiolase family
FPS98_RS29305	COG0183	Belongs to the thiolase family
FPS98_RS29335	COG0410	ABC transporter
FPS98_RS29345	COG0840	transmembrane signaling receptor activity
FPS98_RS29350	COG3396	Phenylacetate-CoA oxygenase
FPS98_RS29365	COG2151	metal-sulfur cluster biosynthetic enzyme
FPS98_RS29370	COG1012	belongs to the aldehyde dehydrogenase family
FPS98_RS29380	COG3336	cytochrome c oxidase
FPS98_RS29390	COG0109	protoheme IX farnesyltransferase activity
FPS98_RS29395	COG1612	heme a metabolic process
FPS98_RS29405	COG0420	3'-5' exonuclease activity
FPS98_RS29410	COG0419	ATPase involved in DNA repair
FPS98_RS29415	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FPS98_RS29430	COG2318	DinB family
FPS98_RS29435	COG0531	amino acid
FPS98_RS29450	COG0477	Major facilitator Superfamily
FPS98_RS29460	COG0789	Transcriptional regulator
FPS98_RS29465	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FPS98_RS29465	COG0551	DNA topoisomerase type I activity
FPS98_RS29470	COG0346	lactoylglutathione lyase activity
FPS98_RS29475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FPS98_RS29480	COG1131	(ABC) transporter
FPS98_RS29485	COG0842	Transport permease protein
FPS98_RS29490	COG1309	transcriptional regulator
FPS98_RS29495	COG0788	formyltetrahydrofolate deformylase activity
FPS98_RS29520	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FPS98_RS29540	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FPS98_RS29545	COG1098	S1 RNA binding domain
FPS98_RS29555	COG0583	DNA-binding transcription factor activity
FPS98_RS29560	COG1506	peptidase
FPS98_RS29565	COG4191	Histidine kinase
FPS98_RS29570	COG1744	ABC transporter substrate-binding protein PnrA-like
FPS98_RS29580	COG2201	protein-glutamate methylesterase activity
FPS98_RS29590	COG0477	Major facilitator Superfamily
FPS98_RS29600	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FPS98_RS29600	COG2508	Transcriptional regulator
FPS98_RS29605	COG0686	Belongs to the AlaDH PNT family
FPS98_RS29625	COG0167	dihydroorotate dehydrogenase activity
FPS98_RS29630	COG0310	cobalt ion transport
FPS98_RS29635	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
FPS98_RS29645	COG1122	ATPase activity
FPS98_RS29665	COG2207	Transcriptional regulator
FPS98_RS29670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPS98_RS29675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPS98_RS29680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FPS98_RS29695	COG1376	ErfK ybiS ycfS ynhG family protein
FPS98_RS29705	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FPS98_RS29710	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FPS98_RS29755	COG0306	phosphate transporter
FPS98_RS29760	COG1392	Phosphate transport regulator
FPS98_RS29765	COG1279	arginine transmembrane transporter activity
FPS98_RS29770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FPS98_RS29775	COG5577	PFAM Coat F domain
FPS98_RS29790	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FPS98_RS29815	COG1131	(ABC) transporter
FPS98_RS29830	COG1024	Enoyl-CoA hydratase
FPS98_RS29830	COG1250	3-hydroxyacyl-CoA dehydrogenase
FPS98_RS29835	COG0183	Belongs to the thiolase family
FPS98_RS29840	COG1960	acyl-CoA dehydrogenase activity
FPS98_RS29860	COG0697	spore germination
FPS98_RS29875	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FPS98_RS29880	COG0235	Class ii aldolase
FPS98_RS29885	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
FPS98_RS29890	COG1850	ribulose-bisphosphate carboxylase activity
FPS98_RS29895	COG1595	DNA-templated transcription, initiation
FPS98_RS29905	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FPS98_RS29910	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FPS98_RS29915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FPS98_RS29920	COG1132	(ABC) transporter
FPS98_RS29925	COG1132	(ABC) transporter
FPS98_RS29930	COG0477	Major facilitator Superfamily
FPS98_RS29935	COG2340	Cysteine-rich secretory protein family
FPS98_RS29945	COG0616	signal peptide processing
FPS98_RS29950	COG1126	abc transporter atp-binding protein
FPS98_RS29965	COG1393	Belongs to the ArsC family
FPS98_RS29970	COG0436	Aminotransferase
FPS98_RS29975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FPS98_RS29980	COG0509	glycine decarboxylation via glycine cleavage system
FPS98_RS29985	COG0840	transmembrane signaling receptor activity
FPS98_RS30010	COG1473	amidohydrolase
FPS98_RS30015	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FPS98_RS30025	COG0396	ATPase activity
FPS98_RS30030	COG0719	Fe-S assembly protein
FPS98_RS30035	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FPS98_RS30040	COG0822	iron-sulfur transferase activity
FPS98_RS30045	COG0719	Fe-S assembly protein
FPS98_RS30100	COG2268	Band 7 protein
FPS98_RS30110	COG0527	aspartate kinase activity
FPS98_RS30120	COG1801	Protein of unknown function DUF72
FPS98_RS30125	COG0730	response to heat
FPS98_RS30130	COG0737	Belongs to the 5'-nucleotidase family
FPS98_RS30140	COG3377	Domain of unknown function (DUF1805)
FPS98_RS30155	COG0598	Magnesium transport protein CorA
FPS98_RS30160	COG0702	epimerase
FPS98_RS30170	COG0840	transmembrane signaling receptor activity
FPS98_RS30195	COG3852	Histidine kinase
FPS98_RS30200	COG2204	response regulator
FPS98_RS30205	COG3258	Cytochrome c
FPS98_RS30225	COG1011	Hydrolase
FPS98_RS30230	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FPS98_RS30230	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FPS98_RS30240	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FPS98_RS30240	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FPS98_RS30245	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FPS98_RS30275	COG0739	heme binding
FPS98_RS30280	COG0693	protein deglycase activity
FPS98_RS30285	COG0420	3'-5' exonuclease activity
FPS98_RS30295	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FPS98_RS30305	COG4470	Protein conserved in bacteria
FPS98_RS30320	COG1494	fructose-1,6-bisphosphatase
FPS98_RS30330	COG2445	Protein of unknown function DUF86
FPS98_RS30350	COG0647	UMP catabolic process
FPS98_RS30355	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FPS98_RS30365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FPS98_RS30375	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FPS98_RS30380	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FPS98_RS30385	COG0626	cystathionine gamma-synthase activity
FPS98_RS30390	COG4837	Protein of unknown function (DUF1462)
FPS98_RS30415	COG1252	NADH dehydrogenase
FPS98_RS30425	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FPS98_RS30435	COG0316	Belongs to the HesB IscA family
FPS98_RS30465	COG1408	metallophosphoesterase
FPS98_RS30495	COG1252	NADH dehydrogenase
FPS98_RS30515	COG3584	3D domain protein
FPS98_RS30525	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FPS98_RS30535	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FPS98_RS30540	COG1832	CoA-binding protein
FPS98_RS30545	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FPS98_RS30555	COG0840	transmembrane signaling receptor activity
FPS98_RS30605	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FPS98_RS30630	COG1396	sequence-specific DNA binding
FPS98_RS30635	COG1476	TRANSCRIPTIONal